OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Bone Oncology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
#15. Single-cell discovery and multi-omic characterization of therapeutic targets in multiple myeloma	94
From bimodal to unimodal: The transformed incidence of osteosarcoma in the United States	50
Postoperative outcomes of subaxial cervical spine metastasis: Comparison among the anterior, posterior, and combined approaches	45
Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma	43
Chinese expert consensus on the diagnosis and clinical management of medication-related osteonecrosis of the jaw	39
MAT2A inhibits the ferroptosis in osteosarcoma progression regulated by miR-26b-5p	36
Senescence in the bone marrow microenvironment: A driver in development of therapy-related myeloid neoplasms	34
Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets	27
Macrophage heterogeneity in bone metastasis	25
State-of-the-art of minimally invasive treatments of bone metastases	21
Adoption of adjuvant bisphosphonates for early breast cancer into standard clinical practice: Challenges and lessons learnt from comparison of the UK and Australian experience	20
#41. Discovery of novel tubulin code in bone metastasis of breast cancer	20
Frequency and reason for reoperation following non-invasive expandable endoprostheses: A systematic review	20
Radiomics model based on MRI to differentiate spinal multiple myeloma from metastases: A two-center study	20
#1. Acid ceramidase (ASAH1) is a key mediator of drug resistance in relapsed/refractory multiple myeloma	20
Targeting the IGF/PI3K/mTOR pathway and AXL/YAP1/TAZ pathways in primary bone cancer	18
A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors	18
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response	18
Preoperative prediction of high-grade osteosarcoma response to neoadjuvant therapy based on a plain CT radiomics model: A dual-center study	17
Association of androgen receptor and tumour-infiltrating lymphocytes with bone recurrence in triple-negative breast cancer	17
#6. Mechanical loading of breast cancer laden bones alters osteocyte mediated bone loss in vivo	15
#49. Complete estrogen-deprived athymic nude mice are susceptible to changes in metabolism and musculoskeletal function mediated by a high-fat diet	15
#2. Homing of intestinal NK and Th1 cells to the tumor site restrains melanoma bone growth in a gut microbiome dependent manner	14
#31. A Phase I/II trial of ATI-2231 with Phase Ia in advanced soild tumor malignancies followed by Phase Ib/II in combination with capecitabine in patients with hormone receptor-positive (HR+) and HER	14
#23. Elucidating the role of bone marrow stiffness in estrogen signaling in metastatic breast cancer to the bone	14

Periacetabular reconstruction following limb-salvage surgery for pelvic sarcomas	13
Using a combination of gangliosides and cell surface vimentin as surface biomarkers for isolating osteosarcoma cells in microfluidic devices	13
Zoledronic acid in metastatic castrate-sensitive prostate cancer: A state-of-the-art review	13
The perplexing role of immuno-oncology drugs in osteosarcoma	13
Intraosseous conventional central chondrosarcoma does not metastasise irrespective of grade in pelvis, scapula and in long bone locations	13
Molecular imaging of bone metastasis	12
Targeting stromal p38MAPKalpha triggers innate-adaptive anti-tumor immunity and sensitizes metastatic breast cancer to immunotherapy	12
Clinical and dosimetric risk factors for vertebral compression fracture after single-fraction stereotactic body radiation therapy for spine metastases	12
LncRNA SATB2-AS1 promotes tumor growth and metastasis and affects the tumor immune microenvironment in osteosarcoma by regulating SATB2	12
FemurTumorNet: Bone tumor classification in the proximal femur using DenseNet model based on radiographs	12
#14. Determining how prostate cancer cell heterogeneity promotes bone metastasis using fluid-walled microfluidics	12
Reprogramming of glucose metabolism: Metabolic alterations in the progression of osteosarcoma	11
Impact of myosteatosis on prognosis in multiple myeloma patients: A subgroup analysis of 182 cases and development of a nomogram	11
Immune checkpoint inhibitors in bone metastasis: Clinical challenges, toxicities, and mechanisms	11
Incidence and radiotherapy treatment patterns of complicated bone metastases	11
The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties	11
#8. Radium-223 treated primary patient bone biopsy analysis: Macro to microscale analyses and dosimetry	10
Multicenter study on atypical femoral fractures in patients with bone metastases taking bone- modifying agents	10
#50. Investigating the role of EphA2 in breast cancer bone metastasis	10
#51. High dimensional profiling of human prostate metastatic bone marrow microenvironment using mass cytometry	10
The roles of the FL/FLT3 axis in the development of cancer-induced bone pain mediated by prostate cancer	10
#45. Fatty acid binding proteins may modulate myeloma in Fabp4/5 double knockout mouse	9
YBX1-interacting small RNAs and RUNX2 can be blocked in primary bone cancer using CADD522	9
Does liquid nitrogen recycled autograft for treatment of bone sarcoma impact local recurrence rate? A systematic review	9
Mixed reality infrastructure based on deep learning medical image segmentation and 3D visualization for bone tumors using DCU-Net	9
#7. Downstream effects of Gli2 targeting on tumor-immune cell crosstalk in bone metastatic breast cancer	9
Molecular pathological insights into tumorigenesis and progression of giant cell tumor of bone	9
Identification of GPC3 mutation and upregulation in a multidrug resistant osteosarcoma and its spheroids as therapeutic target	9
Giant cell tumor of bone: A single center study of 115 cases	9
Automatic classification of spinal osteosarcoma and giant cell tumor of bone using optimized DenseNet	9
Bones and guts – Why the microbiome matters	9
Latest developments in the pathobiology of Ewing sarcoma	9
Use of FVB Myc-CaP cells as an immune competent, androgen receptor positive, mouse model of prostate cancer bone metastasis	8
Prediction of vertebral fractures in cancer patients undergoing hormone deprivation therapies: Reliability of WHO fracture risk assessment tool (FRAX) and bone mineral density in real-life clinical pr	8
Non-POEMS osteosclerotic multiple myeloma: Clinical characteristics and differential diagnosis	8
Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway	8
Current strategies for the treatment of solitary and aneurysmal bone cysts: A review of the literature	8
Circ_0051079 silencing inhibits the malignant phenotypes of osteosarcoma cells by the TRIM66/Wnt/β-catenin pathway in a miR-625-5p-dependent manner	8
A novel adjunctive diagnostic method for bone cancer: Osteosarcoma cell segmentation based on Twin Swin Transformer with multi-scale feature fusion	8
Luteolin attenuates the chemoresistance of osteosarcoma through inhibiting the PTN/β-catenin/MDR1 signaling axis by upregulating miR-384	8
Deep hashing and attention mechanism-based image retrieval of osteosarcoma scans for diagnosis of bone cancer	7
Cav3.2 T-Type calcium channels downregulation attenuates bone cancer pain induced by inhibiting IGF-1/HIF-1α signaling pathway in the rat spinal cord	7
Auxiliary diagnosis of primary bone tumors based on Machine learning model	7
Concurrent capecitabine with external beam radiotherapy versus radiotherapy alone in painful bone metastasis of breast cancer origin	7
Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations	7
Diagnostic value of H3F3A mutation and clinicopathological features of giant cell tumours in non-long bones	7
The role of IL-1B in breast cancer bone metastasis	7
Determinants of tumor necrosis and its impact on outcome in patients with Localized osteosarcoma uniformly treated with a response adapted regimen without high dose Methotrexate– A retrospective insti	7
Groenlandicine enhances cisplatin sensitivity in cisplatin-resistant osteosarcoma cells through the BAX/Bcl-2/Caspase-9/Caspase-3 pathway	7
Real-world patient-reported outcomes of breast cancer or prostate cancer patients receiving antiresorptive therapy for bone metastases: Final results of the PROBone registry study	7

Let-7a suppresses Ewing sarcoma CSCs’ malignant phenotype via forming a positive feedback circuit with STAT3 and lin28	7
The 100 most cited papers on bone metastasis: A bibliometric analysis	7