OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Metabolism is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
GLP-1 receptor agonists in the treatment of type 2 diabetes – state-of-the-art	522
Metabolic dysfunction in polycystic ovary syndrome: Pathogenic role of androgen excess and potential therapeutic strategies	211
Diabetes, infection risk and COVID-19	203
Dysregulated lipid metabolism links NAFLD to cardiovascular disease	197
Metabolic-associated fatty liver disease and lipoprotein metabolism	193
Glucagon-like peptide-1 receptor co-agonists for treating metabolic disease	148
Compartmentalised acyl-CoA metabolism and roles in chromatin regulation	143
A guide to understanding endoplasmic reticulum stress in metabolic disorders	137
Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans	135
Mechanisms of insulin resistance related to white, beige, and brown adipocytes	128
Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street	121
GLP-1 physiology informs the pharmacotherapy of obesity	120
The melanocortin pathway and energy homeostasis: From discovery to obesity therapy	114
Role of NAD+ in regulating cellular and metabolic signaling pathways	108
Insulin action at a molecular level – 100 years of progress	103
Hepatic lipid droplets: A balancing act between energy storage and metabolic dysfunction in NAFLD	100
A non-proliferative role of pyrimidine metabolism in cancer	100
Hepatokines and metabolism: Deciphering communication from the liver	97
Insulin-like growth factors: Ligands, binding proteins, and receptors	95
Metabolic drivers of non-alcoholic fatty liver disease	93
Imaging biomarkers of NAFLD, NASH, and fibrosis	85
The brain as an insulin-sensitive metabolic organ	84
Phosphoenolpyruvate carboxykinase in cell metabolism: Roles and mechanisms beyond gluconeogenesis	73
Genetic and epigenetic factors determining NAFLD risk	72
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis	66

Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2D	64
Targeting the GIPR for obesity: To agonize or antagonize? Potential mechanisms	62
CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing	60
Overexpression of the vitamin D receptor (VDR) induces skeletal muscle hypertrophy	60
Understanding insulin and its receptor from their three-dimensional structures	59
Beta cell identity changes with mild hyperglycemia: Implications for function, growth, and vulnerability	58
GLP-1 improves the supportive ability of astrocytes to neurons by promoting aerobic glycolysis in Alzheimer's disease	58
Ferroptosis and ferritinophagy in diabetes complications	56
Two genomes, one cell: Mitochondrial-nuclear coordination via epigenetic pathways	55
Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation	54
Sodium-glucose co-transporter2 expression and inflammatory activity in diabetic atherosclerotic plaques: Effects of sodium-glucose co-transporter2 inhibitor treatment	54
Mitochondrial oxidative function in NAFLD: Friend or foe?	52
Wnt/β-catenin signaling regulates adipose tissue lipogenesis and adipocyte-specific loss is rigorously defended by neighboring stromal-vascular cells	52
Irisin: Still chasing shadows	52
Infusion of donor feces affects the gut–brain axis in humans with metabolic syndrome	51
Exploring the therapeutic potential of mitochondrial uncouplers in cancer	50
Interactions between metabolism and chromatin in plant models	48
Partial leptin deficiency confers resistance to diet-induced obesity in mice	48
PPARγ and PPARα synergize to induce robust browning of white fat in vivo	47
Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload	46
Cross-omics analysis revealed gut microbiome-related metabolic pathways underlying atherosclerosis development after antibiotics treatment	45
Suppressing adipocyte inflammation promotes insulin resistance in mice	45
Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice	45