OOIR: Observatory of International Research

Papers

(The H4-Index of Redox Biology is 83. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Type 2 Diabetes mellitus alters the cargo of (poly)phenol metabolome and the oxidative status in circulating lipoproteins	354
Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins	322
Microglial Nrf2-mediated lipid and iron metabolism reprogramming promotes remyelination during white matter ischemia	281
Synergistic induction of ferroptosis by targeting HERC1-NCOA4 axis to enhance the photodynamic sensitivity of osteosarcoma	260
Factors driving the inter-individual variability in the metabolism and bioavailability of (poly)phenolic metabolites: A systematic review of human studies	237
The antioxidant and oxidant properties of hydropersulfides (RSSH) and polysulfide species	224
Autophagy activation is required for N6-methyladenosine modification to regulate ferroptosis in hepatocellular carcinoma	208
TRPM7 channel inhibition attenuates rheumatoid arthritis articular chondrocyte ferroptosis by suppression of the PKCα-NOX4 axis	206
Decreased expression of mitochondrial aminoacyl-tRNA synthetases causes downregulation of OXPHOS subunits in type 2 diabetic muscle	194
Corrigendum to “N-butylphthalide (NBP) and ligustrazine (TMP) triazole hybrids target the KEAP1-NRF2 pathway to inhibit ferroptosis and exert brain neuroprotectivity” [Redox Biol. 86, (2025), 103835]	185
A quantitative proteomic approach to evaluate the efficacy of carnosine in a murine model of chronic obstructive pulmonary disease (COPD)	183
Cell cycle induction in human cardiomyocytes is dependent on biosynthetic pathway activation	177
Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer	173
Glutathione peroxidase 3 is essential for countering senescence in adipose remodelling by maintaining mitochondrial homeostasis	171
Human ultrarare genetic disorders of sulfur metabolism demonstrate redundancies in H2S homeostasis	171
Loss of selenoprotein W in murine macrophages alters the hierarchy of selenoprotein expression, redox tone, and mitochondrial functions during inflammation	170
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation	168
Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing	168
Mitochondria spatially and temporally modulate VSMC phenotypes via interacting with cytoskeleton in cardiovascular diseases	162
An inducible long noncoding RNA, LncZFHX2, facilitates DNA repair to mediate osteoarthritis pathology	161
Mechano-activated connexin hemichannels and glutathione transport protect lens fiber cells against oxidative insults	158
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress	156
Organic Selenium induces ferroptosis in pancreatic cancer cells	148
Thioredoxin-interacting protein as a crucial regulator in asthma exacerbation induced by copper oxide nanoparticles in a mouse model	145
Small extracellular vesicles orchestrated pathological communications between breast cancer cells and cardiomyocytes as a novel mechanism exacerbating anthracycline cardiotoxicity by fueling ferroptos	145

Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress	144
Artemether confers neuroprotection on cerebral ischemic injury through stimulation of the Erk1/2-P90rsk-CREB signaling pathway	142
SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc	142
CypD induced ROS output promotes intracranial aneurysm formation and rupture by 8-OHdG/NLRP3/MMP9 pathway	142
Integrated regulation of stress responses, autophagy and survival by altered intracellular iron stores	140
The influence of vitamin D supplementation and strength training on health biomarkers and chromosomal damage in community-dwelling older adults	136
NADPH oxidase 1: A target in the capacity of dimeric ECG and EGCG procyanidins to inhibit colorectal cancer cell invasion	133
FTO ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via P53–P21/Nrf2 activation in a HuR-dependent m6A manner	131
SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential	129
Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice	127
Thioredoxin (Trx): A redox target and modulator of cellular senescence and aging-related diseases	124
Peroxiredoxin 3 deficiency induces cardiac hypertrophy and dysfunction by impaired mitochondrial quality control	122
ROS promote hyper-methylation of NDRG2 promoters in a DNMTS-dependent manner: Contributes to the progression of renal fibrosis	120
GAPDH inhibition mediated by thiol oxidation in human airway epithelial cells exposed to an environmental peroxide	120
Apolipoprotein E is required for brain iron homeostasis in mice	117
Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease	115
Fullerol rescues the light-induced retinal damage by modulating Müller glia cell fate	109
The mammalian peroxisomal membrane is permeable to both GSH and GSSG – Implications for intraperoxisomal redox homeostasis	109
Coronin 1a-mediated F-actin disassembly controls effector function in murine neutrophils	107
OXPHOS inhibition overcomes chemoresistance in triple negative breast cancer	105
Oxidative stress response and NRF2 signaling pathway in autism spectrum disorder	104
Inhibition of spinal ferroptosis-like cell death alleviates hyperalgesia and spontaneous pain in a mouse model of bone cancer pain	104
Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage	104
The protective role of GPX4 in naïve ESCs is highlighted by induced ferroptosis resistance through GPX4 expression	103
PM2.5-induced iron homeostasis imbalance triggers cardiac hypertrophy through ferroptosis in a selective autophagy crosstalk manner	101
A promising drug repurposing approach for Alzheimer's treatment: Givinostat improves cognitive behavior and pathological features in APP/PS1 mice	101
Dimethyl fumarate ameliorates erectile dysfunction in bilateral cavernous nerve injury rats by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis of nerve via activation of Nrf2/HO	101
Oxidative stress following acute kidney injury causes disruption of lung cell cilia and their release into the bronchoaveolar lavage fluid and lung injury, which are exacerbated by Idh2 deletion	100
Development of nitroalkene-based inhibitors to target STING-dependent inflammation	99
A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation	99
REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2	99
Fatty acid nitroalkene reversal of established lung fibrosis	96
A model of mitochondrial superoxide production during ischaemia-reperfusion injury for therapeutic development and mechanistic understanding	94
Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation	94
Role of DDX1 in the oxidative response of ataxia telangiectasia patient-derived fibroblasts	94
Redox shuttle of cytosolic Thioredoxin to mitochondria protects against hyperoxia-mediated alteration of mitochondrial structure and dysfunction	93
Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction	92
Recovery of reduced thiol groups by superoxide-mediated denitrosation of nitrosothiols	92
Nutrigenomics and redox regulation: Concepts relating to the Special Issue on nutrigenomics	91
Inhibition of mitochondrial complex I leading to NAD+/NADH imbalance in type 2 diabetic patients who developed late stent thrombosis: Evidence from an integrative analysis of platelet bioenergetics an	90
Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus	89
Transfer of H2O2 from Mitochondria to the endoplasmic reticulum via Aquaporin-11	89
Selenium deficiency impedes maturation of parvalbumin interneurons, perineuronal nets, and neural network activity	88
Myeloid ACE2 protects against septic hypotension and vascular dysfunction through Ang-(1–7)-Mas-mediated macrophage polarization	88
ALDH2 deficiency increases susceptibility to binge alcohol-induced gut leakiness, endotoxemia, and acute liver injury in mice through the gut-liver axis	88
Corrigendum to “Natural mutations of human XDH promote the nitrite (NO2−)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?” [Redox Biol. 4 (67) (2023) 102864]	88
Acute stimulation of glucose metabolism by H2O2 sustains the NADPH steady-state under oxidative stress	88
Cytoglobin scavenges intracellular hydrogen peroxide and regulates redox signals in the vasculature	87
Supplement-driven iron overload accelerates phenotypic aging via inflammatory biomarkers: Potential counteraction through anti-inflammatory or antioxidant diets	87
Retraction notice to “Autophagy regulates turnover of lipid droplets via ROS-dependent Rab25 activation in hepatic stellate cell” [Redox Biol. 11 (2017) 322–334]	87

Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death	87
The positive feedback loop of the NAT10/Mybbp1a/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I/R injury	86
Dietary sulfur amino acid restriction in humans with overweight and obesity: Evidence of an altered plasma and urine sulfurome, and a novel metabolic signature that correlates with loss of fat mass an	86
Accumulation of acetaldehyde in aldh2.1 zebrafish causes increased retinal angiogenesis and impaired glucose metabolism	86
Mitochondrial cholesterol: Metabolism and impact on redox biology and disease	86
New insights into extracellular and intracellular redox status in COVID-19 patients	85
DRD4 alleviates acute kidney injury by suppressing ISG15/NOX4 axis-associated oxidative stress	83
CircSV2b participates in oxidative stress regulation through miR-5107-5p-Foxk1-Akt1 axis in Parkinson's disease	83