OOIR: Observatory of International Research

Papers

(The H4-Index of Redox Biology is 80. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Basal oxidation of conserved cysteines modulates cardiac titin stiffness and dynamics	407
Special issue on ‘Biomarkers of Oxidative Stress, Aging and Nutrition in Human Studies’	320
Healthspan improvement and anti-aggregation effects induced by a marine-derived structural proteasome activator	287
Discovery and properties of a monoclonal antibody targeting 8-oxoA, an oxidized adenine lesion in DNA and RNA	270
Small extracellular vesicles from senescent stem cells trigger adaptive mechanisms in young stem cells by increasing antioxidant enzyme expression	260
A hydrolysate of poly-trans-[(2-carboxyethyl)germasesquioxane] (Ge-132) suppresses Cav3.2-dependent pain by sequestering exogenous and endogenous sulfide	257
Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases	222
Vitamin D: A master example of nutrigenomics	217
NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression	210
NOX family NADPH oxidases in mammals: Evolutionary conservation and isoform-defining sequences	208
Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4	202
Gut microbiome, short-chain fatty acids, alpha-synuclein, neuroinflammation, and ROS/RNS: Relevance to Parkinson's disease and therapeutic implications	197
Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease	196
The sex steroid precursor dehydroepiandrosterone prevents nonalcoholic steatohepatitis by activating the AMPK pathway mediated by GPR30	182
Nanoparticle endothelial delivery of PGC-1α attenuates hypoxia-induced pulmonary hypertension by attenuating EndoMT-caused vascular wall remodeling	181
BPTF inhibition antagonizes colorectal cancer progression by transcriptionally inactivating Cdc25A	176
An inducible long noncoding RNA, LncZFHX2, facilitates DNA repair to mediate osteoarthritis pathology	176
FTO ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via P53–P21/Nrf2 activation in a HuR-dependent m6A manner	169
Capsaicin ameliorates diabetic retinopathy by inhibiting poldip2-induced oxidative stress	167
Unbalanced redox status network as an early pathological event in congenital cataracts	166
Drug repurposing on Alzheimer's disease through modulation of NRF2 neighborhood	162
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress	153
Corrigendum to “Endothelial Gata6 deletion reduces monocyte recruitment and proinflammatory macrophage formation and attenuates atherosclerosis through Cmpk2-Nlrp3 pathways” [Redox Biol. 64 (2023) 102	145
Adverse bioenergetic effects of N-acyl amino acids in human adipocytes overshadow beneficial mitochondrial uncoupling	144
Glucosinolate-rich broccoli sprouts protect against oxidative stress and improve adaptations to intense exercise training	140

YTHDF1 mitigates acute kidney injury via safeguarding m6A-methylated mRNAs in stress granules of renal tubules	140
Oxidative/nitrosative stress increased the risk of recurrent pregnancy loss–Taiwan Recurrent Pregnancy Loss and Environmental Study (TREPLES)	136
Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response	135
Therapeutic effects of long-term HBOT on Alzheimer's disease neuropathologies and cognitive impairment in APP/PS1 mice	135
Constructing “smart” chelators by using an activatable prochelator strategy for the treatment of Wilson's disease	134
Vascular dysfunction and arterial hypertension in experimental celiac disease are mediated by gut-derived inflammation and oxidative stress	134
SKN-1 is indispensable for protection against Aβ-induced proteotoxicity by a selenopeptide derived from Cordyceps militaris	132
Enteric coronavirus PDCoV evokes a non-Warburg effect by hijacking pyruvic acid as a metabolic hub	127
FBXL4 protects against HFpEF through Drp1-Mediated regulation of mitochondrial dynamics and the downstream SERCA2a	127
SAH is a major metabolic sensor mediating worsening metabolic crosstalk in metabolic syndrome	126
Exogenous APN protects normal tissues from radiation-induced oxidative damage and fibrosis in mice and prostate cancer patients with higher levels of APN have less radiation-induced toxicities	125
JWA binding to NCOA4 alleviates degeneration in dopaminergic neurons through suppression of ferritinophagy in Parkinson's disease	123
A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression	121
S-nitrosoglutathione reductase alleviates morphine analgesic tolerance by restricting PKCα S-nitrosation	120
Pyrogallol intermediates elicit beta-amyloid secretion via radical formation and alterations in intracellular trafficking, distinct from pyrogallol-generated superoxide	118
The absence of the ribosomal protein Rpl2702 elicits the MAPK-mTOR signaling to modulate mitochondrial morphology and functions	117
Therapy-induced senescence through the redox lens	116
Predicting DNA damage response in non-small cell lung cancer organoids via simultaneous label-free autofluorescence multiharmonic microscopy	114
Sustained IKKβ phosphorylation and NF-κB activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56γ3 and PP2A inactivation	114
Mechano-activated connexin hemichannels and glutathione transport protect lens fiber cells against oxidative insults	114
Intracellular peroxynitrite perturbs redox balance, bioenergetics, and Fe–S cluster homeostasis in Mycobacterium tuberculosis	111
Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models	109
Glutathione peroxidase 3 is essential for countering senescence in adipose remodelling by maintaining mitochondrial homeostasis	108
A quantitative proteomic approach to evaluate the efficacy of carnosine in a murine model of chronic obstructive pulmonary disease (COPD)	105
Synergistic induction of ferroptosis by targeting HERC1-NCOA4 axis to enhance the photodynamic sensitivity of osteosarcoma	105
Inhibition of MMP2 activity mitigates N-omega-nitro-l-arginine-methyl ester (l-NAME)-induced right heart failure	102
Overexpression of NUDT16L1 sustains proper function of mitochondria and leads to ferroptosis insensitivity in colorectal cancer	102
Effect of alternative oxidase (AOX) expression on mouse cerebral mitochondria bioenergetics	102
Activation of receptor-independent fluid-phase pinocytosis promotes foamy monocyte formation in atherosclerotic mice	101
Mitochondrial metabolism and redox signaling	99
Cardiac secreted HSP90α exacerbates pressure overload myocardial hypertrophy and heart failure	99
Non-thermal atmospheric pressure plasma-irradiated cysteine protects cardiac ischemia/reperfusion injury by preserving supersulfides	99
Little strokes fell big oaks: The use of weak magnetic fields and reactive oxygen species to fight cancer	98
Nox1/PAK1 is required for angiotensin II-induced vascular inflammation and abdominal aortic aneurysm formation	97
Formation of protein cross-links by singlet oxygen-mediated disulfide oxidation	96
Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour	95
bFGF alleviates diabetes-associated endothelial impairment by downregulating inflammation via S-nitrosylation pathway	95
Editorial	93
Network analysis of nitrate-sensitive oral microbiome reveals interactions with cognitive function and cardiovascular health across dietary interventions	93
Bi-allelic mutation in Fsip1 impairs acrosome vesicle formation and attenuates flagellogenesis in mice	91
Oxidative damage to hyaluronan–CD44 interactions as an underlying mechanism of action of oxidative stress-inducing cancer therapy	91
Induction of reactive oxygen species by mechanical stretch drives endothelin production in neonatal pig renal epithelial cells	90
Increased glycolysis is an early consequence of palmitate lipotoxicity mediated by redox signaling	90
Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure	90
Rhodaneses minimize the accumulation of cellular sulfane sulfur to avoid disulfide stress during sulfide oxidation in bacteria	88
Integrated regulation of stress responses, autophagy and survival by altered intracellular iron stores	87
Vitamin A aldehyde-taurine adducts function in photoreceptor cells	87
Diagnostic and predictive values of circulating tetrahydrobiopterin levels as a novel biomarker in patients with thoracic and abdominal aortic aneurysms	86
Differential endothelial hydrogen peroxide signaling via Nox isoforms: Critical roles for Rac1 and modulation by statins	84
ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA	84

Hindering NAT8L expression in hepatocellular carcinoma increases cytosolic aspartate delivery that fosters pentose phosphate pathway and purine biosynthesis promoting cell proliferation	82
Type 2 Diabetes mellitus alters the cargo of (poly)phenol metabolome and the oxidative status in circulating lipoproteins	82
TXNIP contributes to induction of pro-inflammatory phenotype and caspase-3 activation in astrocytes during Alzheimer’s diseases	81
Genetic hyperactivation of Nrf2 causes larval lethality in Keap1a and Keap1b-double-knockout zebrafish	81
Cysteine hydropersulfide reduces lipid peroxidation and protects against myocardial ischaemia-reperfusion injury - Are endogenous persulfides mediators of ischaemic preconditioning?	81
Loss of glyoxalase 2 alters the glucose metabolism in zebrafish	80