OOIR: Observatory of International Research

Papers

(The H4-Index of Redox Biology is 82. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement	532
Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications	406
Lactate as a fulcrum of metabolism	297
Micro- and nano-plastics activation of oxidative and inflammatory adverse outcome pathways	260
Physical activity and exercise: Strategies to manage frailty	258
NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's diseases	258
The aryl hydrocarbon receptor as a target of environmental stressors – Implications for pollution mediated stress and inflammatory responses	217
Oxidative stress-based therapeutics in COPD	214
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy	197
Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis	195
Complex interplay between autophagy and oxidative stress in the development of pulmonary disease	192
The diverse functionality of NQO1 and its roles in redox control	181
NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy	176
Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway	173
Interrelation between ROS and Ca2+ in aging and age-related diseases	170
HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury	169
Iron dyshomeostasis, lipid peroxidation and perturbed expression of cystine/glutamate antiporter in Alzheimer’s disease: Evidence of ferroptosis	164
Oxidative stress pathways of air pollution mediated toxicity: Recent insights	163
Oxidative eustress: On constant alert for redox homeostasis	154
ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes	152
Dietary patterns and biomarkers of oxidative stress and inflammation: A systematic review of observational and intervention studies	152
PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer	150
Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis	142
Meteorin-like protein attenuates doxorubicin-induced cardiotoxicity via activating cAMP/PKA/SIRT1 pathway	136
Mitigation of the replication of SARS-CoV-2 by nitric oxide in vitro	135

FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells	132
Prediction of survival odds in COVID-19 by zinc, age and selenoprotein P as composite biomarker	131
Identification of Frataxin as a regulator of ferroptosis	131
Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics	130
ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury	128
Innate-adaptive immunity interplay and redox regulation in immune response	128
HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration	127
The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function	126
Plant catalases as NO and H2S targets	125
N6-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cells	122
Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury	122
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer	121
Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy	121
Selenium and selenoproteins in viral infection with potential relevance to COVID-19	121
Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis	117
Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis	113
Epigenetic reprogramming of epithelial-mesenchymal transition promotes ferroptosis of head and neck cancer	113
Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction	112
Antioxidant supplements and endurance exercise: Current evidence and mechanistic insights	111
Nox2 activation in Covid-19	111
Mitochondrial iron–sulfur clusters: Structure, function, and an emerging role in vascular biology	110
Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis	109
Xanthine oxidoreductase: One enzyme for multiple physiological tasks	108
Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia	107
Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence	107
Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-κB and STAT3	106
Breaking the vicious loop between inflammation, oxidative stress and coagulation, a novel anti-thrombus insight of nattokinase by inhibiting LPS-induced inflammation and oxidative stress	105
A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation	105
Protein oxidation - Formation mechanisms, detection and relevance as biomarkers in human diseases	105
Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function	102
Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis	102
Nitric oxide in cellular adaptation and disease	101
Redox toxicology of environmental chemicals causing oxidative stress	101
Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy	101
The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells	100
Expression profiling meta-analysis of ACE2 and TMPRSS2, the putative anti-inflammatory receptor and priming protease of SARS-CoV-2 in human cells, and identification of putative modulators	100
Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway	97
Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway	95
Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions	93
Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes	93
FUNDC1-dependent mitophagy induced by tPA protects neurons against cerebral ischemia-reperfusion injury	93
Short-chain fatty acids as modulators of redox signaling in health and disease	92
Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism	92
The role of selenium in type-2 diabetes mellitus and its metabolic comorbidities	91
XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury	91
Phosphoglycerate mutase 5 exacerbates cardiac ischemia-reperfusion injury through disrupting mitochondrial quality control	91
Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction	89
Iron overload in the motor cortex induces neuronal ferroptosis following spinal cord injury	89
Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation	88
The PINK1/PARK2/optineurin pathway of mitophagy is activated for protection in septic acute kidney injury	87

Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injur	87
Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II–induced hypertension	86
Ergothioneine, recent developments	85
SOD1 suppresses pro-inflammatory immune responses by protecting against oxidative stress in colitis	85
Extracellular superoxide dismutase, a molecular transducer of health benefits of exercise	83
The role of nitric oxide in brain disorders: Autism spectrum disorder and other psychiatric, neurological, and neurodegenerative disorders	82
The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia	82