Journal of Orthopaedic Translation

Papers
(The median citation count of Journal of Orthopaedic Translation is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Near-infrared smart responsive orthopedic implants with synergistic antimicrobial and bone integration-promoting properties288
Epidemiological profiles and intervention strategies of limb deformities in China: A nationwide study based on the largest orthopedic database in China122
Metformin prevents mandibular bone loss in a mouse model of accelerated aging by correcting dysregulated AMPK-mTOR signaling and osteoclast differentiation120
From polarity to pathology: Decoding the role of cell orientation in osteoarthritis98
Targeting Piezo1 channel to alleviate intervertebral disc degeneration64
Histone modifications: Unveiling the epigenetic enigma of degenerative skeletal diseases64
Commentary: “Evolutionary course of the femoral head osteonecrosis: Histopathological - radiologic characteristics and clinical staging systems”60
Several concerns on grading lumbar disc degeneration on MR image with Pfirrmann criteria60
Regulation of mitochondrial dynamic equilibrium by physical exercise in sarcopenia: A systematic review53
Treatment of tibial plateau fractures: A comparison of two different operation strategies with medium-term follow up53
Capability of auxetic femoral stems to reduce stress shielding after total hip arthroplasty51
Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study51
Biomimicking design of artificial periosteum for promoting bone healing48
Forkhead box O3 attenuates osteoarthritis by suppressing ferroptosis through inactivation of NF-κB/MAPK signaling46
Clinical and omics biomarkers in osteoarthritis diagnosis and treatment45
Internal fixation with biodegradable high purity magnesium screws in the treatment of ankle fracture44
A perspective on reoperations after surgical treatments of degenerative lumbar diseases43
RO5126766 attenuates osteoarthritis by inhibiting osteoclastogenesis and protecting chondrocytes through mediating the ERK pathway43
Targeting MAT2A synergistically induces DNA damage in osteosarcoma cells through EZH2-mediated H3K27me3 modification42
Exosomes from umbilical cord mesenchymal stem cells ameliorate intervertebral disc degeneration via repairing mitochondrial dysfunction41
Specific microRNAs are associated with fracture healing phases, patient age and multi-trauma40
Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice39
Mussel-inspired extracellular matrix-mimicking hydrogel scaffold with high cell affinity and immunomodulation ability for growth factor-free cartilage regeneration34
Advances in experimental models of osteonecrosis of the femoral head34
2023 January issue Journal of Orthopaedic Translation33
Triptolide attenuates inhibition of ankylosing spondylitis-derived mesenchymal stem cells on the osteoclastogenesis through modulating exosomal transfer of circ-011063432
Addressing musculoskeletal diseases by exploring the potentials of stem cells and plant-derived chemicals32
Comparison of Kindlin-2 deficiency-stimulated osteoarthritis-like lesions induced by Prg4 versus Aggrecan transgene in mice31
Does the regulation of skeletal muscle influence cognitive function? A scoping review of pre-clinical evidence31
Corrigendum to ‘JD-312 – A novel small molecule that facilitates cartilage repair and alleviates osteoarthritis progression’[Journal of Orthopaedic Translation 44 (2024) 60–71]29
Artificial ligaments in anterior cruciate ligament reconstruction: Coating strategies for PET-based materials29
Development of a standardized and reproducible murine femoral distraction osteogenesis model29
Evaluation of biological performance of 3D printed trabecular porous tantalum spine fusion cage in large animal models28
Gut-bone axis perturbation: Mechanisms and interventions via gut microbiota as a primary driver of osteoporosis28
Epigenetic reprogramming via EZH2 inhibition rescues fibroadipose pathogenesis in secondary lymphedema through activating PPARγ signaling28
Corrigendum to ‘Guideline for adolescent scoliosis screening in China (Public Version 2024)’ [J Orthop Translation, Volume 50, January 2025, Pages 364-372]28
Porous metal materials for applications in orthopedic field: A review on mechanisms in bone healing28
From scientific discovery to orthopaedic clinical innovation28
Regulating inflammation microenvironment and tenogenic differentiation as sequential therapy promotes tendon healing in diabetic rats27
Association between hypertension and osteoarthritis: A systematic review and meta-analysis of observational studies27
Osteocyte β1 integrin loss causes low bone mass and impairs bone mechanotransduction in mice27
Stem cell-based therapeutic strategies for rotator cuff tendinopathy25
Stress stimulation maintaining by genipin crosslinked hydrogel promotes annulus fibrosus healing25
The Revolution of exosomes: From biological functions to therapeutic applications in skeletal muscle diseases25
Molecular signaling in temporomandibular joint osteoarthritis25
Bone microarchitecture assessed by 3D high-resolution peripheral quantitative computed tomography (HR-pQCT) as predictor of fracture risk in patients with glucocorticoid-induced osteoporosis24
The novel magnesium–titanium hybrid cannulated screws for the treatment of vertical femoral neck fractures: Biomechanical evaluation24
Moderate static magnetic field regulates iron metabolism and salvage bone loss caused by iron accumulation24
An innovative self-stabilised 3D-printed artificial vertebral body designed for clinical application and comparison with the conventional implants23
Letter to the editor regarding “Promotion of bone-tendon healing after ACL reconstruction using scaffold-free constructs comprising ADSCs produced by a bio-3D printer in rabbit models”23
GPX4 activator enhances neuroprotection and functional recovery in spinal cord injury23
Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling23
Daily low-intensity pulsed ultrasound stimulation mitigates joint degradation and pain in a post-traumatic osteoarthritis rat model22
Narirutin mitigates inflammatory arthritis and osteoporosis through modulating macrophage phenotype and osteoclastogenesis22
Eurycomanone stimulates bone mineralization in zebrafish larvae and promotes osteogenic differentiation of mesenchymal stem cells by upregulating AKT/GSK-3β/β-catenin signaling22
Establishment and characterization of an inflammatory cartilaginous organoids model for organoid transplantation study22
Scoliosis assessment tools to reduce follow-up X-rays22
Commentary: “Baicalein mediates the anti-tumor activity in Osteosarcoma through lncRNA-NEF driven Wnt/β-catenin signaling regulatory axis”22
Salivary nitrate prevents osteoporosis via regulating bone marrow mesenchymal stem cells proliferation and differentiation21
Mitochondrial Transplantation/Transfer: Promising Therapeutic Strategies for Spinal Cord Injury21
Establishment of a clinically relevant beagle model for periprosthetic joint infection with 3D-printed prostheses and multimodal evaluation21
Regenerative strategies for intervertebral disc degeneration21
Osteoarthritis: A complicated joint disease requiring extensive studies with multiple approaches21
Ubiquitination and deubiquitination: Implications for the pathogenesis and treatment of osteoarthritis21
Cerebrospinal fluid-derived extracellular vesicles after spinal cord injury promote vascular regeneration via PI3K/AKT signaling pathway21
Relieving oxidative stress microenvironment and promoting vascularized bone formation to treat femoral head necrosis using 3D-printed scaffold with ultralong-term multienzyme-like activity21
PINK1-mediated mitophagy contributes to glucocorticoid-induced cathepsin K production in osteocytes20
Sustained BMP-2 delivery via alginate microbeads and polydopamine-coated 3D-Printed PCL/β-TCP scaffold enhances bone regeneration in long bone segmental defects20
Melatonin suppresses bone marrow adiposity in ovariectomized rats by rescuing the imbalance between osteogenesis and adipogenesis through SIRT1 activation20
Tibial cortex transverse transport regulates Orai1/STIM1-mediated NO release and improve the migration and proliferation of vessels via increasing osteopontin expression20
The transplantation of particulated juvenile allograft cartilage and synovium for the repair of meniscal defect in a lapine model20
Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicity in vitro and pro-inflammatory cytokines in vivo20
COVID-19 hip fracture outcomes: The role of Ct values and D-dimer levels?20
Gli1 depletion induces oxidative stress and apoptosis of nucleus pulposus cells via Fos in intervertebral disc degeneration20
Controlled growth factor delivery system with osteogenic-angiogenic coupling effect for bone regeneration20
Dynamic finite element analyses to compare the influences of customised total talar replacement and total ankle arthroplasty on foot biomechanics during gait20
Fibrocartilage hyalinization: A potential therapeutic strategy for articular fibrocartilage19
Role of oxidative stress in mitochondrial dysfunction and their implications in intervertebral disc degeneration: Mechanisms and therapeutic strategies19
Zhuangyao Jianshen Wan ameliorates senile osteoporosis in SAMP6 mice through Modulation of the GCN5L1-mediated PI3K/Akt/wnt signaling pathway19
Electric currents in disc health: The role of ion channels in intervertebral disc pathophysiology19
A novel device for treatment of osteonecrosis of femoral head: Feasibility and preliminary efficacy of animal study19
Bone marrow-derived myeloid cells drive neuroinflammation in Alzheimer's disease: Insights from the FAD4T mouse model19
Addressing musculoskeletal disorders through new treatment strategies19
From “academic success” to “commercial success” —The model of medical device translation driven by SCI articles19
The role of Piezo1 in bone marrow stem cells in response to elevated intraosseous pressure on regulating osteogenesis and angiogenesis of steroid-induced osteonecrosis of the femoral head19
Naringin inhibits the osteoblast-osteoclast pyroptosis cascade reaction mediated by accumulated bone marrow adipose tissue in the treatment of postmenopausal osteoporosis18
Hype or hope of hyaluronic acid for osteoarthritis: Integrated clinical evidence synthesis with multi-organ transcriptomics18
Targeting ANT1 to regulate PINK1/Parkin-mediated mitophagy is an effective treatment of trauma-induced tendon heterotopic ossification18
Randomized control trial of mesenchymal stem cells versus hyaluronic acid in patients with knee osteoarthritis – A Hong Kong pilot study18
General recommendation for assessment and management on the risk of glucocorticoid-induced osteonecrosis in patients with COVID-1918
Kindlin-2 deletion in osteoprogenitors causes severe chondrodysplasia and low-turnover osteopenia in mice18
Correlations between paraspinal extensor muscle endurance and clinical outcomes in preoperative LSS patients and clinical value of an endurance classification17
Endocytosis-associated patterns in nerve regeneration after peripheral nerve injury17
A static magnetic field enhances the repair of osteoarthritic cartilage by promoting the migration of stem cells and chondrogenesis17
Three-dimensional distribution of subchondral fracture lines in osteonecrosis of the femoral head17
Implants coating strategies for antibacterial treatment in fracture and defect models: A systematic review of animal studies17
Pyroptosis-related crosstalk in osteoarthritis: Macrophages, fibroblast-like synoviocytes and chondrocytes16
Bridging basic science and clinical practice in orthopaedic translational research16
Autologous osteoperiosteal transplantation achieves comparable repair effect and superior interface integration to autologous osteochondral transplantation in porcine osteochondral defects16
Design of internal fixation implants for fracture: A review16
Four-year comparative analysis of return to sport and psychological recovery following ACL revision: Artificial ligament vs. anterior tibial tendon allograft15
Dihydroartemisinin ameliorates hemarthrosis-induced cartilage degeneration by suppressing chondrocyte senescence via activation of Keap1-Nrf2 signaling pathway15
Risk-stratified lifetime risk and incidence of hip fracture and falls in middle-aged and elderly Chinese population: The China health and retirement longitudinal study15
Ferroptosis-mediated immune responses in osteoporosis15
Harnessing the potential of hyaluronic acid methacrylate (HAMA) hydrogel for clinical applications in orthopaedic diseases15
Inhibition of ERK1/2 mediated activation of Drp1 alleviates intervertebral disc degeneration via suppressing pyroptosis and apoptosis in nucleus pulposus cells14
Sargassum polysaccharide attenuates osteoarthritis in rats and is associated with the up-regulation of the ITGβ1-PI3K-AKT signaling pathway14
Evolutionary course of the femoral head osteonecrosis: Histopathological - radiologic characteristics and clinical staging systems14
Augmenting osteoporotic osseointegration through a temporal release nanocoating-based reversing dysregulated osteogenic microenvironment14
T cell related osteoimmunology in fracture healing: Potential targets for augmenting bone regeneration14
AMPK activator decelerates osteoarthritis development by inhibition of β-catenin signaling in chondrocytes14
Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-κB pathway14
The involvement of signaling pathways in the pathogenesis of osteoarthritis: An update13
1–2 ​T static magnetic field combined with Ferumoxytol prevent unloading-induced bone loss by regulating iron metabolism in osteoclastogenesis13
Immunoporosis: The hidden link between aging immune cells and bone fragility13
Advancing medical device regulatory reforms for innovation, translation and industry development in China13
Chronic pain after spine surgery: Insights into pathogenesis, new treatment, and preventive therapy13
Targeting the GLP-1/GLP-1R axis to treat osteoarthritis: A new opportunity?13
Promotion of bone-tendon healing after ACL reconstruction using scaffold-free constructs comprising ADSCs produced by a bio-3D printer in rabbit models13
Irisin reduces bone fracture by facilitating osteogenesis and antagonizing TGF-β/Smad signaling in a growing mouse model of osteogenesis imperfecta13
SPARCL1 promotes chondrocytes extracellular matrix degradation and inflammation in osteoarthritis via TNF/NF-κB pathway13
Evaluation of interbody fusion efficacy and biocompatibility of a polyetheretherketone/calcium silicate/porous tantalum cage in a goat model13
Corrigendum to ‘N6-methyladenosine and intervertebral disc degeneration: Advances in detection and pathological insights’ [J Orthop Translat 53 (2025) 38–51/JOT 941]13
PLGA/β-TCP composite scaffold incorporating cucurbitacin B promotes bone regeneration by inducing angiogenesis13
Phillygenin inhibits neuroinflammation and promotes functional recovery after spinal cord injury via TLR4 inhibition of the NF-κB signaling pathway12
Response to the letter to editor regarding “finite element analysis of subtalar joint arthroereisis on adult acquired flexible flatfoot deformity using customized sinus tarsi implant”12
The effect of local sympatholysis on bone-tendon interface healing in a murine rotator cuff repair model12
Current progress and trends in musculoskeletal research: Highlights of NSFC-CUHK academic symposium on bone and joint degeneration and regeneration12
Hydrogel adhesives with a hydrodynamically induced liquid–solid transition for annular fissure sealing and inflammation modulation following microdiscectomy12
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate muscle atrophy via the miR-132-3p/FoxO3 axis12
Radiomics signature of osteoarthritis: Current status and perspective12
Comparative biomechanical analyses of lower cervical spine post anterior fusion versus intervertebral disc arthroplasty: A geometrically patient-specific poroelastic finite element investigation12
Gallic acid mediates tumor-suppressive effects on osteosarcoma through the H19-Wnt/β-catenin regulatory axis12
LRP1 mitigates intervertebral disc degeneration by inhibiting endoplasmic reticulum stress through stabilizing the PPARγ12
Hip joint-preserving strategies for treating osteonecrosis of the femoral head: From nonoperative to operative procedures12
Cycloastragenol prevents bone loss via inhibiting osteoclast activity in glucocorticoid-induced osteonecrosis of the femoral head: An in vivo study12
Silence of HOTAIR promotes osteogenic differentiation and accelerates distraction osteogenesis by mediating FTO ubiquitination11
Solute transport from synovial fluid to articular cartilage and subchondral bone at different stages of osteoarthritis in a live mouse model11
A new attempt to build damaged cartilage11
Repair of the femoral head osteochondral defect in a swine model using autologous costal cartilage graft transplantation11
Therapeutic effect of edaravone on osteoarthritis: targeting NRF2 signaling and mitochondrial function11
IHH–GLI-1–HIF-2α signalling influences hypertrophic chondrocytes to exacerbate osteoarthritis progression11
Intradiscal injection of human recombinant BMP-4 does not reverse intervertebral disc degeneration induced by nuclectomy in sheep11
Augmentation of functional recovery via ROCK/PI3K/AKT pathway by Fasudil Hydrochloride in a rat sciatic nerve transection model11
Corrigendum to “Chk2 deletion rescues bone loss and cellular senescence induced by Bmi1 deficiency via regulation of Cyp1a1” [J Orthop Translat, 52 (2025) 360–375 /doi.org/10.1016/j.jot.2025.04.014]11
Single-cell RNA sequencing reveals resident progenitor and vascularization-associated cell subpopulations in rat annulus fibrosus11
SHP2-mediated ROS activation induces chondrocyte paraptosis in osteoarthritis and is attenuated by low-intensity pulsed ultrasound11
LOXL2 alleviates post-traumatic knee osteoarthritis and pain10
Inhibition of PI3K/AKT signaling pathway prevents blood-induced heterotopic ossification of the injured tendon10
Schnurri-3 controls osteogenic fate of Adipoq-lineage progenitors in bone marrow10
Innovative strategies for bone organoid: Synergistic application and exploration of advanced technologies10
Construction of biomimetic cell-sheet-engineered periosteum with a double cell sheet to repair calvarial defects of rats10
Ischemic preconditioning upregulates Mitofusin2 and preserves muscle strength in tourniquet-induced ischemia/reperfusion10
Exploring molecular and cellular signaling pathways: Unraveling the pathogenesis of tendinopathy10
Single-cell transcriptomics identifies the common perturbations of monocyte/macrophage lineage cells in inflammaging of bone marrow10
Biodegradable magnesium implant enhances angiogenesis and alleviates medication-related osteonecrosis of the jaw in rats10
Aging and musculoskeletal health10
Automatic phantom-less QCT system with high precision of BMD measurement for osteoporosis screening: Technique optimisation and clinical validation10
l-arginine promotes angio-osteogenesis to enhance oxidative stress-inhibited bone formation by ameliorating mitophagy10
Upregulation of ACSL1 in synovial macrophages promotes lipid peroxidation via the IκB/NF-κB pathway to accelerate osteoarthritis10
Exogenous Indian hedgehog antagonist damages intervertebral discs homeostasis in adult mice10
Activation of LAMP1-mediated lipophagy by sulforaphane inhibits cellular senescence and intervertebral disc degeneration10
Looking forward to a better 2023 and beyond10
Construction of organoids using bioprinting technology: a frontier exploration of cartilage repair9
RPL35 downregulated by mechanical overloading promotes chondrocyte senescence and osteoarthritis development via Hedgehog-Gli1 signaling9
Cuproptosis in osteoarthritis: Exploring chondrocyte cuproptosis and therapeutic avenues9
Sclerostin inhibition in rare bone diseases: Molecular understanding and therapeutic perspectives9
Anti-inflammatory and pro-anabolic effects of 5-aminosalicylic acid on human inflammatory osteoarthritis models9
Basic research is the foundation and driving force for clinical translation9
A template to develop humanized technologies that meet true clinical needs9
Single-cell transcriptomic analysis reveals AP-1 downregulation remodels bone marrow environment and contributes to osteopenia in ovariectomized mice9
Innovative development of robot reduction system in geriatric pelvic fractures: A single-center case series in Beijing, China9
Unveiling MiR-3085-3p as a modulator of cartilage degeneration in facet joint osteoarthritis: A novel therapeutic target9
Efficacy and safety of unilateral tibial cortex transverse transport on bilateral diabetic foot ulcers: A propensity score matching study9
ChatGPT for scientific writing — The coexistence of opportunities and challenges9
Magnetic resonance imaging techniques for the quantitative analysis of skeletal muscle: State of the art9
Corrigendum to ‘YAP maintains cartilage stem/progenitor cell homeostasis in osteoarthritis’[Journal of Orthopaedic Translation 46 (2024) 79–90]9
Chinese expert consensus on failure and revision after anterior cruciate ligament reconstruction9
MFG-E8 promotes tendon-bone healing by regualting macrophage efferocytosis and M2 polarization after anterior cruciate ligament reconstruction9
Sipeimine ameliorates osteoarthritis progression by suppression of NLRP3 inflammasome-mediated pyroptosis through inhibition of PI3K/AKT/NF-κB pathway: An in vitro and in vivo study9
Corrigendum to ‘Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice’ [J. Orthop. Transl.] 38 (2023) 241–255]9
An aptamer specifically targeting mCRP ameliorates experimental arthritis9
Moldable self-setting and bioactive bone wax for bone hemostasis and defect repair8
Fibroblast growth factor receptor 3 mutation promotes HSPB6-mediated cuproptosis in hypochondroplasia by impairing chondrocyte autophagy8
Animal model for tendinopathy8
A 3D-printed scaffold composed of Alg/HA/SIS for the treatment of diabetic bone defects8
Synovial organoids: From fundamental construction to groundbreaking applications in arthritic disorders8
Corrigendum to “Gallic acid mediates tumor-suppressive effects on osteosarcoma through the H19-Wnt/β-catenin regulatory axis” [J. Orthop. Translat. 39 (2023) 34–42].8
Classification and pathoanatomy of posterior malleolus fracture based on posterior malleolus-associated ligaments and ankle stability8
Prevalence, risk factors, microbiological results and clinical outcome in unexpected positive intraoperative cultures in unclear and presumed aseptic hip and knee revision arthroplasties – A ten-year 8
Current advances in animal model of meniscal injury: From meniscal injury to osteoarthritis8
Transient activation of notch signaling enhances endogenous stromal cell expansion and subsequent bone defect repair8
JP4-039 protects chondrocytes from ferroptosis to attenuate osteoarthritis progression by promoting Pink1/Parkin-dependent mitophagy8
Intermittent fasting promotes repair of rotator cuff injury in the early postoperative period by regulating the gut microbiota8
Bioabsorbable magnesium-based bulk metallic glass composite (BMGC) for improved medial opening wedge high tibial osteotomy in knee osteoarthritis8
G protein-coupled receptor 30 activation inhibits ferroptosis and protects chondrocytes against osteoarthritis8
Targeted activation on Bnip3 enhances mitophagy to prevent the progression of osteoarthritis8
MLK3 silence suppressed osteogenic differentiation and delayed bone formation via influencing the bone metabolism and disturbing MAPK signaling8
Injectable adipose-derived stem cells-embedded alginate-gelatin microspheres prepared by electrospray for cartilage tissue regeneration8
Preclinical validation of finite element models for predicting in vivo residual plate bending using continuous implant sensor data8
Kartogenin-enhanced dynamic hydrogel ameliorates intervertebral disc degeneration via restoration of local redox homeostasis8
Letter to the editor regarding “Finite element analysis of subtalar joint arthroereisis on adult-acquired flexible flatfoot deformity using customised sinus tarsi implant”8
A novel image-based machine learning model with superior accuracy and predictability for knee arthroplasty loosening detection and clinical decision making8
Neuropeptide Y1 receptor antagonist alleviated osteoarthritis by restoring chondrocyte autophagy through PI3K/AKT/mTOR signaling pathway7
Trends, inequalities and time-series based prediction of knee osteoarthritis attributed to high body-mass-index: findings from global burden of disease 20217
Clinical guideline on the third generation minimally invasive surgery for hallux valgus7
Engineering a functional ACL reconstruction graft containing a triphasic enthesis-like structure in bone tunnel for the enhancement of graft-to-bone integration7
High-dose romosozumab promoted bone regeneration of critical-size ulnar defect filled with demineralized bone matrix in nonhuman primates7
Epidemiological trends and characteristics of osteoarthritis in China during 1990–20217
Comparative effect of skeletal stem cells versus bone marrow mesenchymal stem cells on rotator cuff tendon-bone healing7
Modulating macrophage polarization for the enhancement of fracture healing, a systematic review7
Modulating design parameters to drive cell invasion into hydrogels for osteochondral tissue formation7
Time trends in the burden of low back pain and its associated risk factors in China from 1990 to 20197
Computational screening of biomarkers and potential drugs for arthrofibrosis based on combination of sequencing and large nature language model7
The mitochondrial protectant SS31 optimized decellularized Wharton's jelly scaffold improves allogeneic chondrocyte implantation-mediated articular cartilage repair7
Extracellular matrix in skeletal muscle injury and atrophy: mechanisms and therapeutic implications7
Pip5k1c expression in osteocytes regulates bone remodeling in mice7
Oncostatin-M functionalized cryogel microspheres for promoting diabetic bone defects regeneration7
Distinctive roles of tumor necrosis factor receptor type 1 and type 2 in a mouse disc degeneration model6
Therapeutic potential of a prominent dihydroxyflavanone pinocembrin for osteolytic bone disease: In vitro and in vivo evidence6
Memantine attenuates the development of osteoarthritis by blocking NMDA receptor mediated calcium overload and chondrocyte senescence6
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function6
Macropinocytosis fuels osteoclast differentiation in bone-related diseases6
Immunoregulatory orchestrations in osteoarthritis and mesenchymal stromal cells for therapy6
The effect of drug holiday on preventing medication-related osteonecrosis of the jaw in osteoporotic rat model6
The role of metabolites in the progression of osteoarthritis: Mechanisms and advances in therapy6
A novel application perspective of the clinical-used drug verapamil on osteoporosis via targeting Txnip6
A biodegradable magnesium phosphate cement incorporating chitosan and rhBMP-2 designed for bone defect repair6
Therapeutic effect of human umbilical cord mesenchymal stem cells in early traumatic osteonecrosis of the femoral head6
Upregulation of FABP4 induced inflammation in the pathogenesis of chronic tendinopathy6
Denosumab biosimilar (LY06006) in Chinese postmenopausal osteoporotic women: A randomized, double-blind, placebo-controlled, multicenter phase III study6
Identification of the miRNAome in human fracture callus and nonunion tissues6
Innovation and Translation of Biological and Biomaterial Treatment for Challenging Musculoskeletal Disorders6
Comprehensive analysis of N6-methyladenosine (m6A) modification during the degeneration of lumbar intervertebral disc in mice6
Shock wave assisted intracellular delivery of antibiotics against bone infection with Staphylococcus aureus via P2X7 receptors6
Exosomes secreted by hypoxia-stimulated bone-marrow mesenchymal stem cells promote grafted tendon-bone tunnel healing in rat anterior cruciate ligament reconstruction model6
Application of biphasic mineralized collagen/polycaprolactone scaffolds in the repair of large load-bearing bone defects: A study in a sheep model6
Chk2 deletion rescues bone loss and cellular senescence induced by Bmi1 deficiency via regulation of Cyp1a16
The role of multi-omics in biomarker discovery, diagnosis, prognosis, and therapeutic monitoring of tissue repair and regeneration processes6
Role of YAP/TAZ in bone diseases: A transductor from mechanics to biology6
Mediation of mechanically adapted TiCu/TiCuN/CFR-PEEK implants in vascular regeneration to promote bone repair in vitro and in vivo5
New developments in osteoporosis, osteoarthritis and soft tissue repair5
Platelet-derived extracellular vesicles formulated with hyaluronic acid gels for application at the bone-implant interface: An animal study5
Diagnosis and treatment of anterior cruciate ligament injuries: Consensus of Chinese experts part II: Graft selection and clinical outcome evaluation5
Metformin attenuates diabetes-induced osteopenia in rats is associated with down-regulation of the RAGE-JAK2-STAT1 signal axis5
Loss of Bcl-3 delays bone fracture healing through activating NF-κB signaling in mesenchymal stem cells5
Appreciable biosafety, biocompatibility and osteogenic capability of 3D printed nonstoichiometric wollastonite scaffolds favorable for clinical translation5
YAP maintains cartilage stem/progenitor cell homeostasis in osteoarthritis5
MACF1 overexpression in BMSCs alleviates senile osteoporosis in mice through TCF4/miR-335–5p signaling pathway5
The IRF1/GBP5 axis promotes osteoarthritis progression by activating chondrocyte pyroptosis5
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