Journal of Orthopaedic Translation

Papers
(The median citation count of Journal of Orthopaedic Translation is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Treatment of tibial plateau fractures: A comparison of two different operation strategies with medium-term follow up167
Epidemiological profiles and intervention strategies of limb deformities in China: A nationwide study based on the largest orthopedic database in China143
From polarity to pathology: Decoding the role of cell orientation in osteoarthritis88
Biomimicking design of artificial periosteum for promoting bone healing73
Near-infrared smart responsive orthopedic implants with synergistic antimicrobial and bone integration-promoting properties68
Revisiting osteoarthritis pathogenesis through the lens of cGAS-STING: Mitochondrial damage, pyroptosis, and inflammatory cascades64
Forkhead box O3 attenuates osteoarthritis by suppressing ferroptosis through inactivation of NF-κB/MAPK signaling64
Internal fixation with biodegradable high purity magnesium screws in the treatment of ankle fracture60
CEST MRI: Translational prospects for intervertebral disc degeneration – from basic research to clinical applications59
Histone modifications: Unveiling the epigenetic enigma of degenerative skeletal diseases54
Capability of auxetic femoral stems to reduce stress shielding after total hip arthroplasty52
Protective effects of irisin in sarcopenia: a promising treatment48
Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study48
Txnip regulates glycolysis and tricarboxylic acid cycle balance to maintain bone homeostasis46
Metformin prevents mandibular bone loss in a mouse model of accelerated aging by correcting dysregulated AMPK-mTOR signaling and osteoclast differentiation45
Targeting Piezo1 channel to alleviate intervertebral disc degeneration42
2023 January issue Journal of Orthopaedic Translation41
Clinical and omics biomarkers in osteoarthritis diagnosis and treatment41
A perspective on reoperations after surgical treatments of degenerative lumbar diseases39
TRIM59 alleviates neuronal ferroptosis and promotes functional recovery after spinal cord injury by mediating ubiquitination and degradation of ANXA239
Addressing musculoskeletal diseases by exploring the potentials of stem cells and plant-derived chemicals39
Foot and ankle biomaterials: a comprehensive review of current applications, challenges, and future directions39
Does the regulation of skeletal muscle influence cognitive function? A scoping review of pre-clinical evidence36
Targeting MAT2A synergistically induces DNA damage in osteosarcoma cells through EZH2-mediated H3K27me3 modification35
Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice35
Comparison of Kindlin-2 deficiency-stimulated osteoarthritis-like lesions induced by Prg4 versus Aggrecan transgene in mice35
Organoids and organs-on-chips for accelerating R&D and clinical translation in Orthopaedics: Emerging opportunities and regulatory pathways34
Triptolide attenuates inhibition of ankylosing spondylitis-derived mesenchymal stem cells on the osteoclastogenesis through modulating exosomal transfer of circ-011063434
RO5126766 attenuates osteoarthritis by inhibiting osteoclastogenesis and protecting chondrocytes through mediating the ERK pathway33
Targeting synovial inflammation in knee osteoarthritis: translational insights for diagnosis and therapy33
Exosomes from umbilical cord mesenchymal stem cells ameliorate intervertebral disc degeneration via repairing mitochondrial dysfunction31
Advances in experimental models of osteonecrosis of the femoral head31
Specific microRNAs are associated with fracture healing phases, patient age and multi-trauma31
Multifunctional ultrafast hydrogel for arthroscopic surgery: An enzymatically cross-linked, nanosilicate-reinforced system promotes dual cartilage and subchondral bone regeneration30
Spatially resolved single-cell-based histocytomorphometry for growth plate analysis across multiple species30
The Revolution of exosomes: From biological functions to therapeutic applications in skeletal muscle diseases30
Artificial ligaments in anterior cruciate ligament reconstruction: Coating strategies for PET-based materials30
From scientific discovery to orthopaedic clinical innovation30
Stress stimulation maintaining by genipin crosslinked hydrogel promotes annulus fibrosus healing29
Corrigendum to ‘Guideline for adolescent scoliosis screening in China (Public Version 2024)’ [J Orthop Translation, Volume 50, January 2025, Pages 364-372]29
Corrigendum to ‘JD-312 – A novel small molecule that facilitates cartilage repair and alleviates osteoarthritis progression’[Journal of Orthopaedic Translation 44 (2024) 60–71]29
The novel magnesium–titanium hybrid cannulated screws for the treatment of vertical femoral neck fractures: Biomechanical evaluation28
Epigenetic reprogramming via EZH2 inhibition rescues fibroadipose pathogenesis in secondary lymphedema through activating PPARγ signaling28
Evaluation of biological performance of 3D printed trabecular porous tantalum spine fusion cage in large animal models28
Stem cell-based therapeutic strategies for rotator cuff tendinopathy28
RETRACTED: Regulating inflammation microenvironment and tenogenic differentiation as sequential therapy promotes tendon healing in diabetic rats28
Insights into predicting residual plate bending in vivo using sensor-informed finite element models28
Development of a standardized and reproducible murine femoral distraction osteogenesis model28
Porous metal materials for applications in orthopedic field: A review on mechanisms in bone healing28
Gut-bone axis perturbation: Mechanisms and interventions via gut microbiota as a primary driver of osteoporosis27
Establishment and characterization of an inflammatory cartilaginous organoids model for organoid transplantation study26
An innovative self-stabilised 3D-printed artificial vertebral body designed for clinical application and comparison with the conventional implants26
Salivary nitrate prevents osteoporosis via regulating bone marrow mesenchymal stem cells proliferation and differentiation26
Letter to the editor regarding “Promotion of bone-tendon healing after ACL reconstruction using scaffold-free constructs comprising ADSCs produced by a bio-3D printer in rabbit models”26
Scoliosis assessment tools to reduce follow-up X-rays26
Daily low-intensity pulsed ultrasound stimulation mitigates joint degradation and pain in a post-traumatic osteoarthritis rat model26
Regenerative strategies for intervertebral disc degeneration25
Vitamin D deficiency and disease conditions relevant to: Orthopaedic translation25
GPX4 activator enhances neuroprotection and functional recovery in spinal cord injury25
RhoA deficiency in chondrocyte inhibits cartilage fibrosis and ameliorates osteoarthritis progression via SOX4/MMP2 axis25
Bone microarchitecture assessed by 3D high-resolution peripheral quantitative computed tomography (HR-pQCT) as predictor of fracture risk in patients with glucocorticoid-induced osteoporosis25
Cerebrospinal fluid-derived extracellular vesicles after spinal cord injury promote vascular regeneration via PI3K/AKT signaling pathway25
Eurycomanone stimulates bone mineralization in zebrafish larvae and promotes osteogenic differentiation of mesenchymal stem cells by upregulating AKT/GSK-3β/β-catenin signaling25
Moderate static magnetic field regulates iron metabolism and salvage bone loss caused by iron accumulation24
Modular de- and re-construction of vascularized osteochondral tissues in an Organ-on-Chip dual-compartment platform24
COVID-19 hip fracture outcomes: The role of Ct values and D-dimer levels?24
Narirutin mitigates inflammatory arthritis and osteoporosis through modulating macrophage phenotype and osteoclastogenesis24
Strontium zinc silicate simultaneously alleviates osteoporosis and sarcopenia in tail-suspended rats via Piezo1-mediated Ca2+ signaling24
Romosozumab increases bone mineral density in postmenopausal Chinese women with osteoporosis: A randomised phase three study24
A novel precision micro-drilling technique for treating osteochondral lesions of the talus with superior cartilage regeneration and early rehabilitation compared with microfracture: a randomized contr23
Establishment of a clinically relevant beagle model for periprosthetic joint infection with 3D-printed prostheses and multimodal evaluation23
Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicity in vitro and pro-inflammatory cytokines in vivo23
Ubiquitination and deubiquitination: Implications for the pathogenesis and treatment of osteoarthritis23
Epigenetic transcriptional regulation of skeletal aging: The emerging role of m6A methylation23
PINK1-mediated mitophagy contributes to glucocorticoid-induced cathepsin K production in osteocytes23
Sustained BMP-2 delivery via alginate microbeads and polydopamine-coated 3D-Printed PCL/β-TCP scaffold enhances bone regeneration in long bone segmental defects23
Gli1 depletion induces oxidative stress and apoptosis of nucleus pulposus cells via Fos in intervertebral disc degeneration22
Cell-based therapies for intervertebral disc degeneration: Navigating the path from promise to clinical reality22
Tibial cortex transverse transport regulates Orai1/STIM1-mediated NO release and improve the migration and proliferation of vessels via increasing osteopontin expression22
The neuro–skeletal crosstalk: Mechanisms, clinical implications, and smart material interventions22
Mitochondrial Transplantation/Transfer: Promising Therapeutic Strategies for Spinal Cord Injury21
Melatonin suppresses bone marrow adiposity in ovariectomized rats by rescuing the imbalance between osteogenesis and adipogenesis through SIRT1 activation21
Dynamic finite element analyses to compare the influences of customised total talar replacement and total ankle arthroplasty on foot biomechanics during gait21
Relieving oxidative stress microenvironment and promoting vascularized bone formation to treat femoral head necrosis using 3D-printed scaffold with ultralong-term multienzyme-like activity21
Optimising bionic pore designs in a spiral blade implant to enhance bone ingrowth and stability: A combined CFD and large-animal study21
From cartilage–sensory nerve crosstalk to clinically actionable pain phenotyping in osteoarthritis21
Author's reply to the Letters regarding “A micro-drilling technique for treating osteochondral lesions of talus with superior early rehabilitation compared with microfracture”20
Randomized control trial of mesenchymal stem cells versus hyaluronic acid in patients with knee osteoarthritis – A Hong Kong pilot study20
From “academic success” to “commercial success” —The model of medical device translation driven by SCI articles20
Addressing musculoskeletal disorders through new treatment strategies20
Bone marrow-derived myeloid cells drive neuroinflammation in Alzheimer's disease: Insights from the FAD4T mouse model20
Zhuangyao Jianshen Wan ameliorates senile osteoporosis in SAMP6 mice through Modulation of the GCN5L1-mediated PI3K/Akt/wnt signaling pathway20
Activation of α2-adrenergic receptors as a therapeutic strategy for immune rejection in post-surgery osteosarcoma recurrence treatment20
Electric currents in disc health: The role of ion channels in intervertebral disc pathophysiology20
The role of Piezo1 in bone marrow stem cells in response to elevated intraosseous pressure on regulating osteogenesis and angiogenesis of steroid-induced osteonecrosis of the femoral head19
Fibrocartilage hyalinization: A potential therapeutic strategy for articular fibrocartilage19
Antibiotic-free antimicrobial functionalization of PEEK via UV-induced self-initiation and N-halamine grafting19
Role of oxidative stress in mitochondrial dysfunction and their implications in intervertebral disc degeneration: Mechanisms and therapeutic strategies19
Three-dimensional distribution of subchondral fracture lines in osteonecrosis of the femoral head18
Brain–bone axis dysregulation: Biological code underlying the bidirectional association between depression and musculoskeletal disorders18
The brain–gut–joint axis in arthritis: crosstalk, treatment, and future perspectives18
Targeting ANT1 to regulate PINK1/Parkin-mediated mitophagy is an effective treatment of trauma-induced tendon heterotopic ossification18
A static magnetic field enhances the repair of osteoarthritic cartilage by promoting the migration of stem cells and chondrogenesis17
Naringin inhibits the osteoblast-osteoclast pyroptosis cascade reaction mediated by accumulated bone marrow adipose tissue in the treatment of postmenopausal osteoporosis17
Engineering multifunctional microspheres for sequential regulation of osteoimmune microenvironment and bone remodeling balance to promote regeneration of osteoporotic bone defects17
Autologous osteoperiosteal transplantation achieves comparable repair effect and superior interface integration to autologous osteochondral transplantation in porcine osteochondral defects16
Inhibition of ERK1/2 mediated activation of Drp1 alleviates intervertebral disc degeneration via suppressing pyroptosis and apoptosis in nucleus pulposus cells16
Implants coating strategies for antibacterial treatment in fracture and defect models: A systematic review of animal studies16
Gut microbiota and bone aging: Focusing on the gut-X axis modes16
AMPK activator decelerates osteoarthritis development by inhibition of β-catenin signaling in chondrocytes16
Evaluation of testosterone and alendronate coated membranes in osteoporotic fracture and defect model in rats and goats16
Author's reply to the Letters regarding ‘Selecting between UKA and HTO in the grey zone’16
Bridging basic science and clinical practice in orthopaedic translational research16
Corrigendum to “JP4-039 protects chondrocytes from ferroptosis to attenuate osteoarthritis progression by promoting Pink1/Parkin-dependent mitophagy” [J Orthop Transl 51 (2025) 132–144 / doi: 10.1016/16
Pyroptosis-related crosstalk in osteoarthritis: Macrophages, fibroblast-like synoviocytes and chondrocytes16
Ferroptosis-mediated immune responses in osteoporosis16
Design of internal fixation implants for fracture: A review16
Four-year comparative analysis of return to sport and psychological recovery following ACL revision: Artificial ligament vs. anterior tibial tendon allograft16
Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-κB pathway16
Comment on: “Failure analysis and design improvement of retrieved plates from revision surgery”16
Deer antler polypeptides promote osteogenesis for fracture healing via activating neurosensory PGE2/EP4/p-CREB axis16
Dihydroartemisinin ameliorates hemarthrosis-induced cartilage degeneration by suppressing chondrocyte senescence via activation of Keap1-Nrf2 signaling pathway16
Role of collagen VI and IX in mechanotransduction in the cartilage microenvironments: A multiscale in silico examination16
Harnessing the potential of hyaluronic acid methacrylate (HAMA) hydrogel for clinical applications in orthopaedic diseases15
Augmenting osteoporotic osseointegration through a temporal release nanocoating-based reversing dysregulated osteogenic microenvironment15
Evaluation of interbody fusion efficacy and biocompatibility of a polyetheretherketone/calcium silicate/porous tantalum cage in a goat model15
SPARCL1 promotes chondrocytes extracellular matrix degradation and inflammation in osteoarthritis via TNF/NF-κB pathway15
Targeting the glial-fibrotic scar microenvironment after spinal cord injury: From integrated protection to systematic regulation of regenerative balance15
Sargassum polysaccharide attenuates osteoarthritis in rats and is associated with the up-regulation of the ITGβ1-PI3K-AKT signaling pathway15
Redefining orthopaedic translation: Harnessing multi-omics, smart biomaterials, and regenerative immunomodulation15
Mechanistic insights into cartilage-sensory nerve crosstalk in osteoarthritis progression15
Risk-stratified lifetime risk and incidence of hip fracture and falls in middle-aged and elderly Chinese population: The China health and retirement longitudinal study15
Tristetraprolin protects against osteoarthritis by restraining chondrocyte mitochondrial DNA release through post-transcriptional regulation15
T cell related osteoimmunology in fracture healing: Potential targets for augmenting bone regeneration15
The involvement of signaling pathways in the pathogenesis of osteoarthritis: An update15
Corrigendum to ‘N6-methyladenosine and intervertebral disc degeneration: Advances in detection and pathological insights’ [J Orthop Translat 53 (2025) 38–51/JOT 941]14
Advancing medical device regulatory reforms for innovation, translation and industry development in China14
Comparative biomechanical analyses of lower cervical spine post anterior fusion versus intervertebral disc arthroplasty: A geometrically patient-specific poroelastic finite element investigation14
Promotion of bone-tendon healing after ACL reconstruction using scaffold-free constructs comprising ADSCs produced by a bio-3D printer in rabbit models14
1–2 ​T static magnetic field combined with Ferumoxytol prevent unloading-induced bone loss by regulating iron metabolism in osteoclastogenesis14
Myotendinous Junction development and repair14
The effect of local sympatholysis on bone-tendon interface healing in a murine rotator cuff repair model14
Cycloastragenol prevents bone loss via inhibiting osteoclast activity in glucocorticoid-induced osteonecrosis of the femoral head: An in vivo study14
Letter to the Editor regarding “A novel precision micro-drilling technique for treating osteochondral lesions of the talus with superior cartilage regeneration and early rehabilitation compared with m14
Gallic acid mediates tumor-suppressive effects on osteosarcoma through the H19-Wnt/β-catenin regulatory axis14
Irisin reduces bone fracture by facilitating osteogenesis and antagonizing TGF-β/Smad signaling in a growing mouse model of osteogenesis imperfecta14
Immunoporosis: The hidden link between aging immune cells and bone fragility14
Chronic pain after spine surgery: Insights into pathogenesis, new treatment, and preventive therapy14
Response to the letter to editor regarding “finite element analysis of subtalar joint arthroereisis on adult acquired flexible flatfoot deformity using customized sinus tarsi implant”13
Current progress and trends in musculoskeletal research: Highlights of NSFC-CUHK academic symposium on bone and joint degeneration and regeneration13
Asymmetrical paravertebral muscles fibrosis causes progression of adolescent idiopathic scoliosis via myostatin signalling in fibro-adipogenic progenitors13
Silence of HOTAIR promotes osteogenic differentiation and accelerates distraction osteogenesis by mediating FTO ubiquitination13
Radiomics signature of osteoarthritis: Current status and perspective13
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate muscle atrophy via the miR-132-3p/FoxO3 axis13
A scaffold-free cartilage construct fabricated using a bio 3D printer accelerates critical-size bone defect regeneration13
Targeted knockdown of Piezo1 in synovial macrophages attenuates osteoarthritis development13
Repair of the femoral head osteochondral defect in a swine model using autologous costal cartilage graft transplantation13
LRP1 mitigates intervertebral disc degeneration by inhibiting endoplasmic reticulum stress through stabilizing the PPARγ13
Hydrogel adhesives with a hydrodynamically induced liquid–solid transition for annular fissure sealing and inflammation modulation following microdiscectomy13
Augmentation of functional recovery via ROCK/PI3K/AKT pathway by Fasudil Hydrochloride in a rat sciatic nerve transection model13
Phillygenin inhibits neuroinflammation and promotes functional recovery after spinal cord injury via TLR4 inhibition of the NF-κB signaling pathway13
Hip joint-preserving strategies for treating osteonecrosis of the femoral head: From nonoperative to operative procedures13
Corrigendum to “Chk2 deletion rescues bone loss and cellular senescence induced by Bmi1 deficiency via regulation of Cyp1a1” [J Orthop Translat, 52 (2025) 360–375 /doi.org/10.1016/j.jot.2025.04.014]12
IHH–GLI-1–HIF-2α signalling influences hypertrophic chondrocytes to exacerbate osteoarthritis progression12
Re-innervation of neuromuscular junctions by a conductive polypyrrole/silk fibroin/GelMA hydrogel facilitated functional skeletal muscle regeneration following volumetric muscle loss12
Therapeutic effect of edaravone on osteoarthritis: targeting NRF2 signaling and mitochondrial function12
Tendon stem/progenitor cells in heterotopic ossification: functional regulation, molecular mechanisms and targeted therapeutic strategies12
Intradiscal injection of human recombinant BMP-4 does not reverse intervertebral disc degeneration induced by nuclectomy in sheep12
Proteomic biomarkers in rotator cuff disease: Current evidence and translational implications from a systematic review and network analysis12
Single-cell RNA sequencing reveals resident progenitor and vascularization-associated cell subpopulations in rat annulus fibrosus12
Ubiquitination in intervertebral disc degeneration: from mechanisms to potential therapeutic strategies11
Single-cell transcriptomics identifies the common perturbations of monocyte/macrophage lineage cells in inflammaging of bone marrow11
Plasma-derived exosomes from obese knee osteoarthritis aggravate synovitis by promoting cellular senescence of synovial fibroblasts11
Innovative strategies for bone organoid: Synergistic application and exploration of advanced technologies11
Exploring molecular and cellular signaling pathways: Unraveling the pathogenesis of tendinopathy11
Inhibition of PI3K/AKT signaling pathway prevents blood-induced heterotopic ossification of the injured tendon11
Magnetic resonance imaging techniques for the quantitative analysis of skeletal muscle: State of the art11
Exogenous Indian hedgehog antagonist damages intervertebral discs homeostasis in adult mice11
Solute transport from synovial fluid to articular cartilage and subchondral bone at different stages of osteoarthritis in a live mouse model11
Upregulation of ACSL1 in synovial macrophages promotes lipid peroxidation via the IκB/NF-κB pathway to accelerate osteoarthritis11
l-arginine promotes angio-osteogenesis to enhance oxidative stress-inhibited bone formation by ameliorating mitophagy11
USP39 inhibits MLKL phosphorylation and deubiquitination to suppress necroptosis of nucleus pulposus cells and attenuate intervertebral disc degeneration11
Looking forward to a better 2023 and beyond11
Schnurri-3 controls osteogenic fate of Adipoq-lineage progenitors in bone marrow11
Gut-bone axis crosstalk: Microbiota-driven immune-metabolic-neural networks in bone disorders and precision interventions11
How to choose treatment for patients who are eligible for both unicompartmental knee arthroplasty and high tibial osteotomy?11
SHP2-mediated ROS activation induces chondrocyte paraptosis in osteoarthritis and is attenuated by low-intensity pulsed ultrasound11
A template to develop humanized technologies that meet true clinical needs11
LOXL2 alleviates post-traumatic knee osteoarthritis and pain11
Construction of biomimetic cell-sheet-engineered periosteum with a double cell sheet to repair calvarial defects of rats10
Aging and musculoskeletal health10
RPL35 downregulated by mechanical overloading promotes chondrocyte senescence and osteoarthritis development via Hedgehog-Gli1 signaling10
Corrigendum to “Gallic acid mediates tumor-suppressive effects on osteosarcoma through the H19-Wnt/β-catenin regulatory axis” [J. Orthop. Translat. 39 (2023) 34–42].10
Chinese expert consensus on failure and revision after anterior cruciate ligament reconstruction10
CMTM6 promotes synovial proliferation and macrophage polarization by preventing ubiquitination of TAK1 in rheumatoid arthritis10
Silencing SFRP1 in bone mesenchymal stem cells alleviates pediatric B-ALL-driven bone loss by activating Wnt/β-catenin signaling10
Unveiling MiR-3085-3p as a modulator of cartilage degeneration in facet joint osteoarthritis: A novel therapeutic target10
Corrigendum to ‘YAP maintains cartilage stem/progenitor cell homeostasis in osteoarthritis’[Journal of Orthopaedic Translation 46 (2024) 79–90]10
Activation of LAMP1-mediated lipophagy by sulforaphane inhibits cellular senescence and intervertebral disc degeneration10
Macrophage iron overload promotes osteoporosis via Cxcl3- and Cxcl7-mediated paracrine signaling in ovariectomized mice10
Basic research is the foundation and driving force for clinical translation10
Corrigendum to ‘Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice’ [J. Orthop. Transl.] 38 (2023) 241–255]10
Anti-inflammatory and pro-anabolic effects of 5-aminosalicylic acid on human inflammatory osteoarthritis models9
Advancing the continuum of orthopaedic translation: Mechanistic insight, regenerative innovation, and converging technologies9
Cuproptosis in osteoarthritis: Exploring chondrocyte cuproptosis and therapeutic avenues9
Efficacy and safety of unilateral tibial cortex transverse transport on bilateral diabetic foot ulcers: A propensity score matching study9
Osteoarthritis pathogenesis Unveiled: DMT1 drives autophagy-dependent ferroptosis through a mir-17-5p/NEDD4 regulatory axis9
ChatGPT for scientific writing — The coexistence of opportunities and challenges9
Construction of organoids using bioprinting technology: a frontier exploration of cartilage repair9
An aptamer specifically targeting mCRP ameliorates experimental arthritis9
Intermittent fasting promotes repair of rotator cuff injury in the early postoperative period by regulating the gut microbiota9
Kartogenin-enhanced dynamic hydrogel ameliorates intervertebral disc degeneration via restoration of local redox homeostasis9
Bioabsorbable magnesium-based bulk metallic glass composite (BMGC) for improved medial opening wedge high tibial osteotomy in knee osteoarthritis9
Preclinical validation of finite element models for predicting in vivo residual plate bending using continuous implant sensor data8
Moldable self-setting and bioactive bone wax for bone hemostasis and defect repair8
Sipeimine ameliorates osteoarthritis progression by suppression of NLRP3 inflammasome-mediated pyroptosis through inhibition of PI3K/AKT/NF-κB pathway: An in vitro and in vivo study8
G protein-coupled receptor 30 activation inhibits ferroptosis and protects chondrocytes against osteoarthritis8
Innovative development of robot reduction system in geriatric pelvic fractures: A single-center case series in Beijing, China8
A novel image-based machine learning model with superior accuracy and predictability for knee arthroplasty loosening detection and clinical decision making8
Animal model for tendinopathy8
JP4-039 protects chondrocytes from ferroptosis to attenuate osteoarthritis progression by promoting Pink1/Parkin-dependent mitophagy8
Single-cell transcriptomic analysis reveals AP-1 downregulation remodels bone marrow environment and contributes to osteopenia in ovariectomized mice8
Advances of piezoelectric biomaterials in bone defect repair: The role of direct and inverse piezoelectric effect8
Classification and pathoanatomy of posterior malleolus fracture based on posterior malleolus-associated ligaments and ankle stability8
MLK3 silence suppressed osteogenic differentiation and delayed bone formation via influencing the bone metabolism and disturbing MAPK signaling8
Synovial organoids: From fundamental construction to groundbreaking applications in arthritic disorders8
Sclerostin inhibition in rare bone diseases: Molecular understanding and therapeutic perspectives8
A 3D-printed scaffold composed of Alg/HA/SIS for the treatment of diabetic bone defects8
Corrigendum to ‘Author's reply to the letter regarding “CMTM6 promotes synovial proliferation and macrophage polarization by preventing ubiquitination of TAK1 in rheumatoid arthritis”’ [J Orthop Trans8
Effects of early photobiomodulation therapy on motor recovery in patients with incomplete acute cervical spinal cord injury: A multicenter randomized controlled trial8
Fibroblast growth factor receptor 3 mutation promotes HSPB6-mediated cuproptosis in hypochondroplasia by impairing chondrocyte autophagy7
Clinical guideline on the third generation minimally invasive surgery for hallux valgus7
Current advances in animal model of meniscal injury: From meniscal injury to osteoarthritis7
Innovation and Translation of Biological and Biomaterial Treatment for Challenging Musculoskeletal Disorders7
Modulating macrophage polarization for the enhancement of fracture healing, a systematic review7
Time trends in the burden of low back pain and its associated risk factors in China from 1990 to 20197
Extracellular matrix in skeletal muscle injury and atrophy: mechanisms and therapeutic implications7
Engineering a functional ACL reconstruction graft containing a triphasic enthesis-like structure in bone tunnel for the enhancement of graft-to-bone integration7
Targeted activation on Bnip3 enhances mitophagy to prevent the progression of osteoarthritis7
Therapeutic potential of a prominent dihydroxyflavanone pinocembrin for osteolytic bone disease: In vitro and in vivo evidence7
A biodegradable magnesium phosphate cement incorporating chitosan and rhBMP-2 designed for bone defect repair7
Denosumab biosimilar (LY06006) in Chinese postmenopausal osteoporotic women: A randomized, double-blind, placebo-controlled, multicenter phase III study7
The mitochondrial protectant SS31 optimized decellularized Wharton's jelly scaffold improves allogeneic chondrocyte implantation-mediated articular cartilage repair7
Prevalence, risk factors, microbiological results and clinical outcome in unexpected positive intraoperative cultures in unclear and presumed aseptic hip and knee revision arthroplasties – A ten-year 7
Graphene oxide-modified PEEK composites: Properties and applications in orthopaedic repair — A review7
The effect of drug holiday on preventing medication-related osteonecrosis of the jaw in osteoporotic rat model7
Pip5k1c expression in osteocytes regulates bone remodeling in mice7
High-dose romosozumab promoted bone regeneration of critical-size ulnar defect filled with demineralized bone matrix in nonhuman primates7
Modulating design parameters to drive cell invasion into hydrogels for osteochondral tissue formation7
Semaglutide alleviates osteoarthritis independent of weight loss via GLP-1R–mediated activation of autophagy through AKT/mTOR inhibition7
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