OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Orthopaedic Translation is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Special Issue: Metabolic diseases and injuries of skeletal muscles: Current diagnosis, treatment and prevention	219
We miss you, we are all FFF--Mourns from the Chinese orthopaedic sports medicine community	99
Commentary: “Evolutionary course of the femoral head osteonecrosis: Histopathological - radiologic characteristics and clinical staging systems”	72
Mediation of mechanically adapted TiCu/TiCuN/CFR-PEEK implants in vascular regeneration to promote bone repair in vitro and in vivo	63
Exogenous Indian hedgehog antagonist damages intervertebral discs homeostasis in adult mice	63
Accumulation of advanced oxidation protein products aggravates bone-fat imbalance during skeletal aging	50
Hyperbaric oxygen potentiates platelet-rich plasma composition and accelerates bone healing	46
Role of YAP/TAZ in bone diseases: A transductor from mechanics to biology	42
High-speed centrifugation reduces immune rejection by removing bone marrow elements from fresh osteochondral allografts	40
Vibration therapy as an intervention for trochanteric hip fractures – A randomized double-blinded, placebo-controlled trial	39
Piezoelectric biomaterials for providing electrical stimulation in bone tissue engineering: Barium titanate	37
The effect and mechanism of QufengZhitong capsule for the treatment of osteoarthritis in a rat model	35
Krüppel like factor 10 prevents intervertebral disc degeneration via TGF-β signaling pathway both in vitro and in vivo	35
Osseointegrated prostheses for the rehabilitation of patients with transfemoral amputations: A prospective ten-year cohort study of patient-reported outcomes and complications	35
A static magnetic field enhances the repair of osteoarthritic cartilage by promoting the migration of stem cells and chondrogenesis	35
A novel therapy for fracture healing by increasing lymphatic drainage	35
OGT mediated HDAC5 O-GlcNAcylation promotes osteogenesis by regulating the homeostasis of epigenetic modifications and proteolysis	35
The effect of topical administration of simvastatin on entochondrostosis and intramembranous ossification: An animal experiment	35
Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice	31
Endocytosis-associated patterns in nerve regeneration after peripheral nerve injury	30
Correlations between paraspinal extensor muscle endurance and clinical outcomes in preoperative LSS patients and clinical value of an endurance classification	29
Inhibition of PI3K/AKT signaling pathway prevents blood-induced heterotopic ossification of the injured tendon	29
Three-dimensional distribution of subchondral fracture lines in osteonecrosis of the femoral head	29
Regulation of mitochondrial dynamic equilibrium by physical exercise in sarcopenia: A systematic review	28
Schnurri-3 controls osteogenic fate of Adipoq-lineage progenitors in bone marrow	28

A systematic investigation of the effects of TGF-β3 and mechanical stimulation on tenogenic differentiation of mesenchymal stromal cells in a poly(ethylene glycol)/gelatin-based hydrogel	28
Metformin prevents mandibular bone loss in a mouse model of accelerated aging by correcting dysregulated AMPK-mTOR signaling and osteoclast differentiation	28
Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study	28
3-D microarchitectural properties and rod- and plate-like trabecular morphometric properties of femur head cancellous bones in patients with rheumatoid arthritis, osteoarthritis, and osteoporosis	28
Biomimicking design of artificial periosteum for promoting bone healing	27
Corrigendum to ‘Prevalence, risk factors, microbiological results and clinical outcome in unexpected positive intraoperative cultures in unclear and presumed aseptic hip and knee revision arthroplasti	25
Clinical and omics biomarkers in osteoarthritis diagnosis and treatment	25
Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35/NFκB p65 pathway	25
Single-cell transcriptomics identifies the common perturbations of monocyte/macrophage lineage cells in inflammaging of bone marrow	24
Accelerated fracture healing accompanied with traumatic brain injury: A review of clinical studies, animal models and potential mechanisms	24
A novel application perspective of the clinical-used drug verapamil on osteoporosis via targeting Txnip	24
Paeonol inhibits ACSL4 to protect chondrocytes from ferroptosis and ameliorates osteoarthritis progression	23
Targeting Piezo1 channel to alleviate intervertebral disc degeneration	23
Importance to understand medical device regulations for accelerating clinical translation	23
Ischemic preconditioning upregulates Mitofusin2 and preserves muscle strength in tourniquet-induced ischemia/reperfusion	23
Internal fixation with biodegradable high purity magnesium screws in the treatment of ankle fracture	23
Treatment of tibial plateau fractures: A comparison of two different operation strategies with medium-term follow up	22
Several concerns on grading lumbar disc degeneration on MR image with Pfirrmann criteria	21
Treatment effects, adverse outcomes and cardiovascular safety of romosozumab – Existing worldwide data: A systematic review and meta-analysis	21
Cyasterone accelerates fracture healing by promoting MSCs migration and osteogenesis	21
Neural and immune roles in osteoarthritis pain: Mechanisms and intervention strategies	21
Advances in electroactive biomaterials: Through the lens of electrical stimulation promoting bone regeneration strategy	21
Exploring molecular and cellular signaling pathways: Unraveling the pathogenesis of tendinopathy	21
From polarity to pathology: Decoding the role of cell orientation in osteoarthritis	20
FOXO1-mTOR pathway in vascular pericyte regulates the formation of type H vessels to control bone metabolism	20
CD73 alleviates osteoarthritis by maintaining anabolism and suppressing catabolism of chondrocytes extracellular matrix	20
Effect of tibial cortex transverse transport in patients with recalcitrant diabetic foot ulcers: A prospective multicenter cohort study	20
Lateral-anterior lumbar interbody fusion (LaLIF) for lumbar degenerative disease: Technical notes, surgical system, and mid-term outcomes	19
Capability of auxetic femoral stems to reduce stress shielding after total hip arthroplasty	19
l-arginine promotes angio-osteogenesis to enhance oxidative stress-inhibited bone formation by ameliorating mitophagy	19
Appreciable biosafety, biocompatibility and osteogenic capability of 3D printed nonstoichiometric wollastonite scaffolds favorable for clinical translation	19
Biodegradable magnesium implant enhances angiogenesis and alleviates medication-related osteonecrosis of the jaw in rats	19
Implants coating strategies for antibacterial treatment in fracture and defect models: A systematic review of animal studies	19
Automatic phantom-less QCT system with high precision of BMD measurement for osteoporosis screening: Technique optimisation and clinical validation	18
Therapeutics for enhancement of spinal fusion: A mini review	18
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration	18
Forkhead box O3 attenuates osteoarthritis by suppressing ferroptosis through inactivation of NF-κB/MAPK signaling	18
Pyroptosis-related crosstalk in osteoarthritis: Macrophages, fibroblast-like synoviocytes and chondrocytes	18
USP7 promotes the osteoclast differentiation of CD14+ human peripheral blood monocytes in osteoporosis via HMGB1 deubiquitination	18
The IRF1/GBP5 axis promotes osteoarthritis progression by activating chondrocyte pyroptosis	18
Platelet-derived extracellular vesicles formulated with hyaluronic acid gels for application at the bone-implant interface: An animal study	17
The catabolic-to-anabolic shift seen in the canine osteoarthritic cartilage treated with knee joint distraction occurs after the distraction period	17
Risk-stratified lifetime risk and incidence of hip fracture and falls in middle-aged and elderly Chinese population: The China health and retirement longitudinal study	16
Bridging basic science and clinical practice in orthopaedic translational research	16
Harnessing the potential of hyaluronic acid methacrylate (HAMA) hydrogel for clinical applications in orthopaedic diseases	16
A perspective on reoperations after surgical treatments of degenerative lumbar diseases	16
Mechanical loading on osteocytes regulates thermogenesis homeostasis of brown adipose tissue by influencing osteocyte-derived exosomes	16
Magnetic field therapy enhances muscle mitochondrial bioenergetics and attenuates systemic ceramide levels following ACL reconstruction: Southeast Asian randomized-controlled pilot trial	15
Addressing musculoskeletal diseases by exploring the potentials of stem cells and plant-derived chemicals	15
COPB1 deficiency triggers osteoporosis with elevated iron stores by inducing osteoblast ferroptosis	15

RPL35 downregulated by mechanical overloading promotes chondrocyte senescence and osteoarthritis development via Hedgehog-Gli1 signaling	15
Looking forward to a better 2023 and beyond	15
A template to develop humanized technologies that meet true clinical needs	15
Does the regulation of skeletal muscle influence cognitive function? A scoping review of pre-clinical evidence	15
Smoking and osteoimmunology: Understanding the interplay between bone metabolism and immune homeostasis	15
“Innovation and translation of biological and biomaterial treatment for challenging musculoskeletal disorders”	15
2023 January issue Journal of Orthopaedic Translation	15
Continued improvement of translational medicine – A cohesive approach	15
AMPK activator decelerates osteoarthritis development by inhibition of β-catenin signaling in chondrocytes	15
Choosing the right animal model for osteomyelitis research: Considerations and challenges	14
Four-year comparative analysis of return to sport and psychological recovery following ACL revision: Artificial ligament vs. anterior tibial tendon allograft	14
Loss of Bcl-3 delays bone fracture healing through activating NF-κB signaling in mesenchymal stem cells	14
3D ultrasound imaging provides reliable angle measurement with validity comparable to X-ray in patients with adolescent idiopathic scoliosis	14
Translational therapy from preclinical animal models for muscle degeneration after rotator cuff injury	14
Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-κB pathway	14
TBK1 pharmacological inhibition mitigates osteoarthritis through attenuating inflammation and cellular senescence in chondrocytes	14
Bone tissue engineering scaffolds with HUVECs/hBMSCs cocultured on 3D-printed composite bioactive ceramic scaffolds promoted osteogenesis/angiogenesis	14
Hemodynamic stress shapes subchondral bone in osteoarthritis: An emerging hypothesis	13
Unveiling the role of CXCL8/CXCR2 in intervertebral disc degeneration: A path to promising therapeutic strategies	13
New developments in osteoporosis, osteoarthritis and soft tissue repair	13
Comparative proteomic analysis identifies differentially expressed proteins and reveals potential mechanisms of traumatic heterotopic ossification progression	13
Sustained notch signaling inhibition with a gamma-secretase inhibitor prevents traumatic heterotopic ossification	13
Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice	13
Triptolide attenuates inhibition of ankylosing spondylitis-derived mesenchymal stem cells on the osteoclastogenesis through modulating exosomal transfer of circ-0110634	13
Diagnosis and treatment of anterior cruciate ligament injuries: Consensus of Chinese experts part II: Graft selection and clinical outcome evaluation	13
Specific microRNAs are associated with fracture healing phases, patient age and multi-trauma	13
Does concomitant meniscus repair and meniscectomy show different efficacy in anterior cruciate ligament reconstruction? A systematic review and meta-analysis	13
Recent developments in Achilles tendon risk-analyzing rupture factors for enhanced injury prevention and clinical guidance: Current implications of regenerative medicine	12
Advances in osteoarthritis research in 2021 and beyond	12
Biomechanics of a novel artificial cervical vertebra from an in vivo caprine cervical spine non-fusion model	12
Preclinical model for lumbar interbody fusion in small ruminants: Rationale and guideline	12
YAP maintains cartilage stem/progenitor cell homeostasis in osteoarthritis	12
Comparison of Kindlin-2 deficiency-stimulated osteoarthritis-like lesions induced by Prg4 versus Aggrecan transgene in mice	12
Oral versus intravenous tranexamic acid in elderly patients with intertrochanteric fracture undergoing proximal femur intramedullary nailing: A prospective cohort study	12
Autologous osteoperiosteal transplantation achieves comparable repair effect and superior interface integration to autologous osteochondral transplantation in porcine osteochondral defects	12
T cell related osteoimmunology in fracture healing: Potential targets for augmenting bone regeneration	12
The construction of a novel xenograft bovine bone scaffold, (DSS)6-liposome/CKIP-1 siRNA/calcine bone and its osteogenesis evaluation on skull defect in rats	12