OOIR: Observatory of International Research

Papers

(The median citation count of Life Sciences in Space Research is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
IFC - Editorial Board	37
Effect of countermeasure bodygear on cardiac-vascular-respiratory coupling during 6-degree head-down tilt: An earth-based microgravity study	34
Biofilm dynamics in space and their potential for sustainable space exploration – A comprehensive review	31
Organ dose equivalents of albedo protons and neutrons under exposure to large solar particle events during lunar human landing missions	28
Anthocyanin can improve the survival of rice seeds from solar light outside the international space station	26
Challenges and innovations in food and water availability for a sustainable Mars colonization	25
IFC - Editorial Board	23
IFC - Editorial Board	22
A no-fault risk compensation approach for radiation risks incurred in space travel	22
Reorganization of the mouse oocyte' cytoskeleton after cultivation under simulated weightlessness	21
Results from the Radiation Assessment Detector on the International Space Station: Part 1, the Charged Particle Detector	20
Residual radiation risk disparities across sex and race or ethnic groups for lifetime never-smokers on lunar missions	20
RadLab: An open science resource for radiation studies relevant to human spaceflight	19
Galactic cosmic ray environment predictions for the NASA BioSentinel Mission, part 2:Post-mission validation	19
Lignocellulose degradation, biogas production and characteristics of the microbial community in solid-state anaerobic digestion of wheat straw waste	19
Comparative study of methods for detecting extraterrestrial life in exploration mission of Mars and the solar system	17
Construction of microgravity biological knowledge graph and its applications in anti-osteoporosis drug prediction	17
Radiation environment on TGO Mars orbit during solar particle events in January–October 2024. Corresponding solar eruptions and GOES proton fluxes data	16
Analysis of suitable site candidates for Mars human habitat and life-support technologies based on in situ water resource utilization	16
Optimizing autonomous artificial intelligence diagnostics for neuro-ocular health in space missions	15
Behavior of simple closed ecological systems; lower nutrient concentrations allow longer persistence of grazer populations	14
Comparison between PHITS and GEANT4 Simulations of the Heavy Ion Beams at the BEVALAC at LBNL and the Booster Accelerator at BNL	14
Disparity in the effect of partial gravity simulated using a new apparatus on different rat hindlimb muscles	14
The neurology of space flight; How does space flight effect the human nervous system?	14
High-throughput screening strategies for space-based radiation countermeasure discovery	13

Infrared spectroscopy reveals ethylene glycol is an anti-crystallizer in water mixed astrochemical ices	13
Recent progresses on space life science research in China	13
The COSPAR Planetary Protection Policy for robotic missions to Mars: A review of current scientific knowledge and future perspectives	11
Study on primary physicochemical characteristics and nutrient adsorption of four plant cultivation substrates	11
Integrated spaceflight transcriptomic analyses and simulated space experiments reveal key molecular features and functional changes driven by space stressors in space-flown C. elegans	10
A method to predict space radiation biological effectiveness for non-cancer effects following intense Solar Particle Events	10
Transfer learning as an AI-based solution to address limited datasets in space medicine	10
Angiotensin converting enzyme (ACE) inhibitors as radiation countermeasures for long-duration space flights	9
Tissue-specific dose equivalents of secondary mesons and leptons during galactic cosmic ray exposures for mars exploration	9
Simulated space environmental factors of weightlessness, noise and low atmospheric pressure differentially affect the diurnal rhythm and the gut microbiome	9
Accumulation of high-energy phosphates blocks the expression of mitochondrial biogenesis markers and slow-type myosin in soleus muscle under 24 hours of rat hindlimb suspension	9
Effects of social isolation and galactic cosmic radiation on fine motor skills and behavioral performance	9
Involvement of KATANIN1, a microtubule-severing enzyme, in hypergravity-induced modification of growth anisotropy in Arabidopsis hypocotyls	9
Simulated microgravity altered the gene expression profiles and inhibited the proliferation of Kupffer cells in the early phase by downregulating LMO2 and EZH2	9
Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading	9
Results from the Radiation Assessment Detector on the International Space Station, Part 2: The fast neutron detector	8
IFC - Editorial Board	8
Medical countermeasures for the hematopoietic-subsyndrome of acute radiation syndrome in space	8
IFC - Editorial Board	8
Small tissue chips with big opportunities for space medicine	8
Microbes and nutrient shift in a Closed Aquatic Ecosystem (CAES) during four weeks of operation	8
Mimic microgravity effect on muscle transcriptome under ionizing radiation	7
Comparison of the particle flux measured by Liulin-MO dosimeter in ExoMars TGO science orbit with those calculated by models	7
Reduced gravity effects on gait coordinative structures	7
Evolving radiological protection guidelines for exploration-class missions	7
IFC - Editorial Board	7
Cardiovascular adaptations in microgravity conditions	7
Comments on “EcAMSat spaceflight measurements of the role of σs in antibiotic resistance of stationary phase Escherichia coli in microgravity”	7
Solid waste management and resource recovery during the 4-crew 180-day CELSS integrated experiment	7
Active radiation measurements over one solar cycle with two DOSTEL instruments in the Columbus laboratory of the International Space Station	7
Lower body negative pressure as a research tool and countermeasure for the physiological effects of spaceflight: A comprehensive review	7
IFC - Editorial Board	7
Spaceflight validation of technology for point-of-care monitoring of peripheral blood WBC and differential in astronauts during space missions	7
Relationship of collagen as the component of the extracellular matrix with the mechanisms of autonomic regulation of the cardiovascular system under simulated conditions of long-term isolation	6
Corrigendum to ‘RadLab: An open science resource for radiation studies relevant to human spaceflight’ Life Sciences in Space Research Volume 43, November 2024, Pages 29-34	6
Perspective: Leveraging Lower Body Negative Pressure for Enhanced Outcomes in Orthopedic Arthroplasty—Insights from NASA’s Bone Health Research	6
Survival of desert algae Chlorella exposed to Mars-like near space environment	6
Biomechanics of healthy subjects during exercise on a simulated vibration isolation and stabilization system	6
Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice	6
Improving astronaut cancer risk assessment from space radiation with an ensemble model framework	6
IFC - Editorial Board	5
IFC - Editorial Board	5
Optimized crop growth area composition for long duration spaceflight	5
Non-targeted effects and space radiation risks for astronauts on multiple International Space Station and lunar missions	5
Comparative analysis of the molecular response characteristics in Platycodon grandiflorus irradiated with heavy ion beams and X-rays	5
How do we transport plant species with desiccation-sensitive germplasm in space?	5
IFC - Editorial Board	5
Bone deconditioning during partial weight-bearing in rodents – A systematic review and meta-analysis	5
Automated pupillometry in space neuroscience	5
Biology and crop production in Space environments: Challenges and opportunities	5

RRx-001 and the “Right stuff”: Protection and treatment in outer space	5
Space biological and human survival: Investigations into plants, animals, microorganisms and their components and bioregenerative life support systems	5
A non-invasive approach to monitor anemia during long-duration spaceflight with retinal fundus images and deep learning	5
Contemporary review of dermatologic conditions in space flight and future implications for long-duration exploration missions	5
High throughput screen of small molecules as potential countermeasures to galactic cosmic radiation induced cellular dysfunction	5
The influence of simulated weightlessness on the composition and function of gut microbiota and bile acid metabolism products	5
Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model	5
Weighing the impact of microgravity on vestibular and visual functions	4
Biophysics of ophthalmic medications during spaceflight: Principles of ocular fluid dynamics and pharmacokinetics in microgravity	4
Combined irradiation by gamma-rays and carbon-12 nuclei caused hyperlocomotion and change in striatal metabolism of rats	4
Space radiation measured during first-ever commercial suborbital mission on Virgin Galactic SpaceShipTwo Unity on 29 June 2023	4
Medial prefrontal cortex and hippocampus in mice differently affected by simulate microgravity and social isolation associated with the alternation of emotional and cognitive functions	4
Increase in steryl glycoside levels and stimulation of lipid raft formation in azuki bean epicotyls under hypergravity conditions	4
Harnessing nucleic acid technologies for human health on earth and in space	4
Observations of neutron radiation environment during Odyssey cruise to Mars	4
Space station and spacecraft environmental conditions and human mental health: Specific recommendations and guidelines	4
The COSPAR planetary protection policy for missions to Icy Worlds: A review of history, current scientific knowledge, and future directions	4
Development of a NASA roadmap for planetary protection to prepare for the first human missions to Mars	4
Molecular and biomechanical changes of the cornea and lens in spaceflight	4
Integrated analysis of miRNAome and transcriptome reveals that microgravity induces the alterations of critical functional gene modules via the regulation of miRNAs in short-term space-flown C. elegan	4
Characteristics of blood plasma proteome changes associated with the hemorrhagic purpura of cosmonauts on the first day after long-term space missions	4
Treatment with a superoxide dismutase mimetic for joint preservation during 35 and 75 days in orbit aboard the international space station, and after 120 days recovery on Earth	4
The lack of mass transfer in bone lacunar-canalicular system may be the decisive factor of osteoporosis under microgravity	4
What can space radiation protection learn from radiation oncology?	4
Food Technologies for Space Missions	4
HERA: A Timepix-based radiation detection system for Exploration-class space missions	4
Protective effect of Gastrodia elata blume ameliorates simulated weightlessness-induced cognitive impairment in mice	3
Nonhuman primate models in the study of spaceflight stressors: Past contributions and future directions	3
Corrigendum to “Characterization of virulence-related phenotypes of Candida parapsilosis and Rhodotorula mucilaginosa isolated from the International Space Station (ISS)” [Life Sciences in Space Resea	3
Crew time in a space greenhouse using data from analog missions and Veggie	3
Compact portable sources of high-LET radiation: Validation and potential application for galactic cosmic radiation countermeasure discovery	3
IFC - Editorial Board	3
Limb position sense and sensorimotor performance under conditions of weightlessness	3
Dynamic visual acuity as a biometric for astronaut performance and safety	3
The COSPAR planetary protection requirements for space missions to Venus	3
Radiation cataract in Heterogeneous Stock mice after γ-ray or HZE ion exposure	3
Galactic cosmic ray simulation at the NASA space radiation laboratory – Progress, challenges and recommendations on mixed-field effects	3
Astrochemistry: The study of chemical processes in space	3
Carbonate precipitation and nitrogen fixation in AMG (Artificial Martian Ground) by cyanobacteria	3
Non-DNA radiosensitive targets that initiate persistent behavioral deficits in rats exposed to space radiation	3
In Memoriam	3
A new type of ground-based simulator of radiation field inside a spacecraft in deep space	3
Considerations for carcinogenesis countermeasure development using mouse models	3
Targeting hippocampal neurogenesis to protect astronauts’ cognition and mood from decline due to space radiation effects	3
3D bioprinting meniscus tissue onboard the International Space Station	3
Effects of hypobaria, hyperoxia, and nitrogen form on the growth and nutritional quality of lettuce	3
Amorphous calcium carbonate enhances osteogenic differentiation and myotube formation of human bone marrow derived mesenchymal stem cells and primary skeletal muscle cells under microgravity condition	3
Cultivation and nutritional characteristics of Chlorella vulgaris cultivated using Martian regolith and synthetic urine	3
Baoyuan jieyu formula ameliorates depression-like behaviour in rats induced by simulated long-term spaceflight composite stress through regulating MAPK and BDNF pathways	2
Reduced set-shifting processing speed in male rats following low dose (10 cGy) proton exposure	2
Applicability of composite materials for space radiation shielding of spacecraft	2
Effects of X-ray irradiation and housing conditions on mitochondria in Peromyscus maniculatus	2
The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats	2
Design and establishment of a large-scale controlled ecological life-support system integrated experimental platform	2
Private Spaceflight: A New Landscape for Dealing with Medical Risk	2
Microglia: Rheostats of space radiation effects in the CNS microenvironment	2
Effects of preexposure to a subthreshold dose of helium particles on the changes in performance produced by exposure to helium particles	2
Characterization of virulence-related phenotypes of Candida parapsilosis and Rhodotorula mucilaginosa isolated from the International Space Station (ISS)	2
Advanced food packaging systems for space exploration missions	2
Plant biology for space exploration – Building on the past, preparing for the future	2
Leaf yield and mineral content of mizuna in response to cut-and-come-again harvest, substrate particle size, and fertilizer formulation in a simulated spaceflight environment	2
The microwave electromagnetic background as measured onboard the International Space Station	2
Corrigendum to ‘Review of research into bioregenerative life support system(s) which can support humans living in space’ [life sciences in space research 31 (2021) 113–120]	2
Neurostimulation as a technology countermeasure for dry eye syndrome in astronauts	2
Gastrodia elata blume ameliorates circadian rhythm disorder-induced mice memory impairment	2
Palmer Station, Antarctica: A ground-based spaceflight analog suitable for validation of biomedical countermeasures for deep space missions	2
Radiation in human space exploration: Detectors and measurements, today and tomorrow	2
Hydroponics for plant cultivation in space – a white paper	2
Application of functional microbial agent in aerobic composting of wheat straw for waste recycling	2
Dose measurements with the Pille-ISS thermoluminescent dosimeter system during extravehicular activities (2004-2022)	2