OOIR: Observatory of International Research

Papers

(The TQCC of Life Sciences in Space Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Anthocyanin can improve the survival of rice seeds from solar light outside the international space station	34
The heavy ion-induced up-regulation of ZIP14 is mediated by the PKC Nrf2 pathway	33
IFC - Editorial Board	31
Physiological safety and Multi-Tissue metabolic adaptation under a novel intermittent prolonged fasting regimen	24
Challenges and innovations in food and water availability for a sustainable Mars colonization	24
Biofilm dynamics in space and their potential for sustainable space exploration – A comprehensive review	21
Organ dose conversion factors for murine galactic cosmic ray irradiation	19
3D culture and cryopreservation/thawing strategy of human induced pluripotent stem cells for spaceflight experiments	18
Organ dose equivalents of albedo protons and neutrons under exposure to large solar particle events during lunar human landing missions	18
From Antarctic regolith to lunar greenhouses: Mechanistic insights into Brassica rapa photosystem II dynamics for sustainable space agriculture	18
Reorganization of the mouse oocyte' cytoskeleton after cultivation under simulated weightlessness	17
A no-fault risk compensation approach for radiation risks incurred in space travel	17
The case for anterior segment optical coherence tomography (AS-OCT) for the international space station and future planetary spaceflight: Clinical relevance and technical implementation	17
Results from the Radiation Assessment Detector on the International Space Station: Part 1, the Charged Particle Detector	16
Residual radiation risk disparities across sex and race or ethnic groups for lifetime never-smokers on lunar missions	16
RadLab: An open science resource for radiation studies relevant to human spaceflight	14
IFC - Editorial Board	13
Domestication of radiation sensitive Caenorhabditis Elegans strains suitable for liquid culture systems in long-term space mission	11
Renal macrostructural and hilar Doppler hemodynamic stability during a 7-day head-down tilt bed rest: an exploratory ultrasound-based study in humans under simulated microgravity	11
Comprehensive omics strategies for space agriculture development	11
Analysis of suitable site candidates for Mars human habitat and life-support technologies based on in situ water resource utilization	10
Radiation environment on TGO Mars orbit during solar particle events in January–October 2024. Corresponding solar eruptions and GOES proton fluxes data	10
Galactic cosmic ray environment predictions for the NASA BioSentinel Mission, part 2:Post-mission validation	9
Study on primary physicochemical characteristics and nutrient adsorption of four plant cultivation substrates	9
Neuroprotective and neuromodulatory role of agmatine in mitigating simulated microgravity-induced cognitive and behavioral deficits in rats	9

Construction of microgravity biological knowledge graph and its applications in anti-osteoporosis drug prediction	9
Behavior of simple closed ecological systems; lower nutrient concentrations allow longer persistence of grazer populations	9
BioKMS-HAG: A hierarchically guided biomedical and space science knowledge fine-grained mining system	9
Optimizing autonomous artificial intelligence diagnostics for neuro-ocular health in space missions	9
Comparative study of methods for detecting extraterrestrial life in exploration mission of Mars and the solar system	9
Disparity in the effect of partial gravity simulated using a new apparatus on different rat hindlimb muscles	9
UHAB-1: Physiological responses to a 48-hour spaceflight analog mission underwater	8
High-throughput screening strategies for space-based radiation countermeasure discovery	8
Digital twin modelling in microgravity: A framework for predictive and personalised space medicine	8
The neurology of space flight; How does space flight effect the human nervous system?	8
Recent progresses on space life science research in China	8
Comprehensive exercise countermeasures for astronauts low back pain in microgravity: A scoping review	8
Infrared spectroscopy reveals ethylene glycol is an anti-crystallizer in water mixed astrochemical ices	7
Simulated microgravity altered the gene expression profiles and inhibited the proliferation of Kupffer cells in the early phase by downregulating LMO2 and EZH2	7
Impact of weightlessness on dynamic deformation and haemodynamic parameters of the heart	7
Pinoresinol diglucoside alleviates hindlimb unloading-induced bone loss in mice	7
Integrated spaceflight transcriptomic analyses and simulated space experiments reveal key molecular features and functional changes driven by space stressors in space-flown C. elegans	7
The COSPAR Planetary Protection Policy for robotic missions to Mars: A review of current scientific knowledge and future perspectives	7
Angiotensin converting enzyme (ACE) inhibitors as radiation countermeasures for long-duration space flights	7
Transfer learning as an AI-based solution to address limited datasets in space medicine	7
Accumulation of high-energy phosphates blocks the expression of mitochondrial biogenesis markers and slow-type myosin in soleus muscle under 24 hours of rat hindlimb suspension	7
The missing discipline in space health operations: Nursing as mission assurance	7
Involvement of KATANIN1, a microtubule-severing enzyme, in hypergravity-induced modification of growth anisotropy in Arabidopsis hypocotyls	7
Tissue-specific dose equivalents of secondary mesons and leptons during galactic cosmic ray exposures for mars exploration	7
A method to predict space radiation biological effectiveness for non-cancer effects following intense Solar Particle Events	7
IFC - Editorial Board	6
Microbes and nutrient shift in a Closed Aquatic Ecosystem (CAES) during four weeks of operation	6
Simulated space environmental factors of weightlessness, noise and low atmospheric pressure differentially affect the diurnal rhythm and the gut microbiome	6
Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading	6
Effects of social isolation and galactic cosmic radiation on fine motor skills and behavioral performance	6
Medical countermeasures for the hematopoietic-subsyndrome of acute radiation syndrome in space	6
Results from the Radiation Assessment Detector on the International Space Station, Part 2: The fast neutron detector	6
IFC - Editorial Board	6
Radiative transfer modeling of the low-mass proto-binary system, IRAS 4A1 and 4A2	6
Musculoskeletal degeneration in space: translational parallels with spaceflight-associated ocular pathology and surgical implications	6
Small tissue chips with big opportunities for space medicine	6
Parabolic flight as a space-flight analogon impacts angiogenesis and lipid metabolism	5
Active radiation measurements over one solar cycle with two DOSTEL instruments in the Columbus laboratory of the International Space Station	5
Solid waste management and resource recovery during the 4-crew 180-day CELSS integrated experiment	5
Reduced gravity effects on gait coordinative structures	5
Impact of gravitational forces on Red Blood Cell dynamics in biofluid suspension	5
Transcriptomics analyses reveal microgravity triggers estrogen synthesis amidst degeneration and aging in human ovarian granulosa cells	5
Sleep deprivation and glymphatic dysfunction: Perspectives on the risk of Spaceflight Associated Neuro-ocular Syndrome (SANS)	5
IFC - Editorial Board	5
Oxidative decarboxylation of L-alanine on hematite: Implications for prebiotic chemistry in planetary environments	5
Simulated microgravity induces a time-dependent shift from autophagy to apoptosis in osteoblasts, validated by TSPO, ATG12, and BNIP3L expression in vivo	5
IFC - Editorial Board	5
Cardiovascular adaptations in microgravity conditions	5
Approaching ocular risks during spaceflight with 3D printing: Technical strategies to protect astronaut vision	5
Parabolic flight as a research platform to investigate ophthalmic changes in microgravity	5

Evolving radiological protection guidelines for exploration-class missions	5
Nutrition-based interventions for mitigating space radiation-induced DNA damage: A systematic review and meta-analysis	5
IFC - Editorial Board	4
Caffeine Consumption Aboard the International Space Station and its Relationship to Sleep and Cognitive Performance	4
Goals and trends in space exploration: An overview of the panel on exploration sessions at the committee on space research general assembly 2024	4
Contemporary review of dermatologic conditions in space flight and future implications for long-duration exploration missions	4
Comparison of the particle flux measured by Liulin-MO dosimeter in ExoMars TGO science orbit with those calculated by models	4
A non-invasive approach to monitor anemia during long-duration spaceflight with retinal fundus images and deep learning	4
Insights into the effect of microgravity on phytopathogens and plant-associated microbes	4
IFC - Editorial Board	4
Space biological and human survival: Investigations into plants, animals, microorganisms and their components and bioregenerative life support systems	4
Bone deconditioning during partial weight-bearing in rodents – A systematic review and meta-analysis	4
Sleep deprivation and glymphatic system dysfunction as a risk factor for SANS during long-duration spaceflight	4
IFC - Editorial Board	4
Lower body negative pressure as a research tool and countermeasure for the physiological effects of spaceflight: A comprehensive review	4
Advancements in health monitoring technologies for astronauts in deep space missions: A Review	4
IFC - Editorial Board	4
Effects of neutron radiation on pharmaceuticals in deep space-like environments - general anesthesia in space	4
The mechanism and protection of microgravity induced cardiac remodeling	4
Synergistic effect of IL-4 and simulated microgravity on osteogenic differentiation of periosteal stem cells	4
How do we transport plant species with desiccation-sensitive germplasm in space?	4
Corrigendum to ‘RadLab: An open science resource for radiation studies relevant to human spaceflight’ Life Sciences in Space Research Volume 43, November 2024, Pages 29-34	4
Effects of clinostat-based microgravity simulation on the growth and differentiation of cerebral organoids using a 3D-clinostat	4
Leveraging lower body negative pressure for enhanced outcomes in orthopedic arthroplasty—Insights from NASA’s bone health research	4
Biomechanics of healthy subjects during exercise on a simulated vibration isolation and stabilization system	4