Asian Pacific Journal of Tropical Biomedicine

Article	Citations
Coleus forskohlii shows anti-psoriatic activity in imiquimod-induced psoriasis rats	32
Icariin plus curcumol enhances autophagy through the mTOR pathway and promotes cathepsin B-mediated pyroptosis of prostate cancer cells	23
Auranofin amplifies schisandrin A-induced apoptosis through ROS generation and inhibiting the PI3K/Akt pathway in hepatocellular carcinoma	21
Protective effects of naringin against oxidative stress, inflammation, apoptosis, and DNA damage in rats with doxorubicin-induced hepatotoxicity	20
Anti-inflammatory effects of Solanum procumbens on a low dose complete Freund's adjuvant-induced arthritis rat model	18
Metabolomics in drug discovery: Restoring antibiotic pipeline	16
Natural sources, biosynthesis, biological functions, and molecular mechanisms of shikimic acid and its derivatives	15
Epigallocatechin-3-gallate exerts antihypertensive effects and improves endothelial function in spontaneously hypertensive rats	15
Anticancer activity of Δ9-tetrahydrocannabinol and cannabinol in vitro and in human lung cancer xenograft	14
Coumarin and eugenol ameliorate LPS-induced inflammation in RAW 264.7 cells via modulating the NLRP3 inflammasome pathway	14
Antiviral efficacy of Andrographis paniculata and andrographolides: A narrative review	13
L-carvone attenuates myocardial injury and dyslipidemia in rats with isoproterenolinduced cardiac hypertrophy	12
Dehydroabietic acid chemosensitizes drug-resistant acute lymphoblastic leukemia cells by downregulating survivin expression	11
Anticancer drug screening of natural products	11
Phellinus igniarius ameliorates renal aging in a rat model of focal and segmental glomerulosclerosis	11
Zinc oxide nanoparticles synthesized with Berberis vulgaris L. ameliorate cyclophosphamide-induced nephrotoxicity in rats	11
Human Wharton's jelly mesenchymal stem cells inhibit cytokine storm in acute respiratory distress syndrome in a rat model	11
Harpephyllum caffrum stimulates glucose uptake, abates redox imbalance and modulates purinergic and glucogenic enzyme activities in oxidative hepatic injury	10
T6SS-5 and the cGAS-STING pathway in Burkholderia pseudomallei infection and immunity	10
Persea americana attenuates inflammatory response associated with hyperlipidemia in ovariectomized and irradiated rats by regulating MMP-3/TIMP-1 levels	10
Celastrol, a bioactive compound from Tripterygium wilfordii, exerts renoprotective effects by modulating the gut-kidney axis and PPAR signaling in a mouse model of diabetic kidney disease	10
Quercetin modulates ovarian autophagy–related molecules and stereological parameters in a rat model of PCOS	9
Ocimum sanctum extract preserves neuronal echotexture and controls seizure in lithium-pilocarpine induced status epilepticus rats	9
Antidepressant and anti-nociceptive effects of Nigella sativa and its main constituent, thymoquinone	9
Noscapine shows antimalarial activity against Plasmodium falciparum 3D7, its clinical isolate Pf140/SS, and Plasmodium berghei ANKA	9

Immune response to inactivated bacterial vector carrying the recombinant K39 antigen of Leishmania infantum in mice	9
Antiosteoporosis and bone protective effect of alpinumisoflavone in steroid-induced osteoporosis rats via alteration of apoptosis, inflammatory and RANK/RANKL/OPG signaling pathway	9
Biosensors	9
Thrombopoietin ameliorates doxorubicin-induced toxicities in H9c2 myocardiocytes by inhibiting oxidative stress through the SIRT1/p38 MAPK signaling pathway	8
Panax ginseng protects against copper sulfate-induced kidney toxicity in rats	8
Lipid-lowering effect of Oroxylum indicum (L.) Kurz extract in hyperlipidemic mice	8
Cryptotanshinone ameliorates cladribine-induced cognitive impairment in rats	8
Chandipura virus: The 2024 resurgence and Gujarat outbreak	8
Semen podocarpi extract enhances radiosensitivity in nasopharyngeal carcinoma cells via Raf/MEK/ERK signaling pathway	7
Essential oil from Saussurea costus inhibits proliferation and migration of Eca109 cells via mitochondrial apoptosis and STAT3 signaling	7
Anti-metastatic potential of OR3 pigment from Streptomyces coelicolor JUACT03 on MDA-MB-231 breast cancer in vitro and in vivo	7
Hepatorenoprotective effects of Lepidium draba L. extracts against cyclophosphamide-induced oxidative injuries in rats via reducing apoptosis and inflammation	7
Gentiana lutea extract ameliorates scopolamine-induced amnesia in mice via cholinergic modulation and inhibition of Aβ/p-tau protein accumulation	7
Synbiotic mulberry ameliorates kidney injury in dextran sodium sulfate-induced colitis rats	7
Acanthus leucostachyus leaf extracts promote excision wound healing in mice	6
Biological functions and diagnostic implications of microRNAs in Mycobacterium tuberculosis infection	6
Unripe Carica papaya protects skin keratinocytes against UVB-induced cell death via antioxidative and anti-inflammatory mechanisms	6
In-silico and in-vitro evaluation of docetaxel and berberine as potential p53 modulating apoptotic inducers in oral squamous cell carcinoma	6
Scopoletin	6
Characterization of the infectivity of an Indonesian Zika virus strain in mammalian cell lines	6
Anti-obesity effect and UHPLC-QTOF-MS/MS based metabolite profiling of Solanum nigrum leaf extract	6
Grifola frondosa polysaccharides alleviate Alzheimer's disease in rats	6
Immunomodulatory activity of polycaprolactone nanoparticles with calcium phosphate salts against Leishmania infantum infection	6
Naringenin nanoparticles show anti-angiogenic activity in HUVECs and a chick chorioallantoic membrane model and anticancer activity in MCF-7 cells	6
Rhamnus crenata leaf extracts exhibit anti-inflammatory activity via modulating the Nrf2/HO-1 and NF-κB/MAPK signaling pathways	5
Boeravinone B ameliorates allergic nasal inflammation by modulating the GATA-3/T-bet signaling pathway in a mouse model of allergic rhinitis	5
Aqueous extract of freeze-dried Protaetia brevitarsis larvae promotes osteogenesis by activating β-catenin signaling	5
Aqueous extract of Protaetia brevitarsis larvae increases mTOR-mediated growth rate in zebrafish larvae	5
Hypoglycaemic, anti-hyperlipidemic, and anti-inflammatory activities of Asparagus africanus (Asparaceae) extract on high-fat diet/streptozotocin-induced diabetes in Wistar rats	5
Astragalus adscendens extract shows antidiabetic effects through controlling oxidative stress, inflammation and apoptosis in streptozotocin-induced diabetic rats	5
Anti-inflammatory potential of black cumin seed oil and its nanoemulsion formulation against lipopolysaccharide-induced liver injury in mice	5
Ponatinib and gossypol act in synergy to suppress colorectal cancer cells by modulating apoptosis/autophagy crosstalk and inhibiting the FGF19/FGFR4 axis	4
Rhus longipes (Engl.) infusions improve glucose metabolism and mitigate oxidative biomarkers in ferrous sulfate-induced renal injury	4
Acknowledgment to Reviewers, 2022	4
Effect of hydroalcoholic leaf extract of Cassia fistula L. on type II collagen-induced arthritis in rats	4
Plant-derived natural compounds in the treatment of arsenic-induced toxicity	4
Nacre extract improves insulin resistance and cognitive functions in diabetic mice	4
Beta-glucan protects against isoproterenol-induced cardiac remodeling by regulating the ACE-AT1R axis and attenuates cardiac inflammation and apoptosis	4
Antioxidant, antimicrobial, and α-glucosidase inhibitory activities of saponin extracts from walnut (Juglans regia L.) leaves	4
Anthrahydroquinone-2,6-disulfonate alleviates paraquat-induced kidney injury via the apelin-APJ pathway in rats	4
CRX-527 as a candidate adjuvant in a recombinant BCG-based malaria vaccine	4
Foeniculum vulgare (Fennel): A comprehensive review of its anti-diabetic properties	4
Natural polysaccharides for ulcerative colitis	4
Antimicrobial properties of Sonchus species: A review	4
Ursolic acid alleviates isoproterenol-induced kidney injury in mice by suppressing inflammation, apoptosis, and oxidative stress via the PI3K/Akt signaling	4
Anti-arthritic effect of Distemonanthus benthamianus extracts against rheumatoid arthritis in rats	4
Salidroside attenuates oxygen and glucose deprivation-induced neuronal injury by inhibiting ferroptosis	3
Antibacterial and anti-parasitic activities of Terfezia claveryi methanolic extract against some common pathogenic agents of infectious diarrhea	3
Hepato- and reno-protective effects of thymoquinone, crocin, and carvacrol	3
Th17/Treg balance and macrophage polarization ratio in lower extremity arteriosclerosis obliterans	3

Methanolic extract of Ephedra alata inhibits breast cancer cells in vitro and in vivo	3
Antioxidant, antimicrobial, and anticancer effects of Achillea filipendulina L. against colon cancer	3
Therapeutic potential of Zataria multiflora: A narrative review of current evidence	3
Molluscicidal effect of green synthesized silver nanoparticles using Azadirachta indica on Biomphalaria alexandrina snails and Schistosoma mansoni cercariae	3
Aptamer technology in latent tuberculosis diagnosis: A systematic review and meta-analysis	3
Trigonelline exerts its neuroprotective effects in experimental spinal cord injury through modulation of inflammation, apoptosis, and neurotrophic factors	3
Erratum to "Boeravinone B ameliorates allergic nasal inflammation by modulating the GATA-3/T-bet signaling pathway in a mouse model of allergic rhinitis"	3
Manool restores glucose homeostasis by regulating JAK/STAT, mTOR, and antioxidant signaling in a type 2 diabetes rat model	2
Asiaticoside ameliorates type 2 diabetes mellitus in rats by modulating carbohydrate metabolism and regulating insulin signaling	2
Interleukin-33 exerts pleiotropic immunoregulatory effects in response to Plasmodium berghei ANKA (PbA) infection in mice	2
Prodigiosin from Serratia	2
Hesperidin attenuates arsenic trioxide-induced cardiac toxicity in rats	2
Antiviral activity of mangiferin from the rhizome of Anemarrhena asphodeloides against herpes simplex virus type 1	2
Gedunin attenuates streptozotocin-induced diabetic hepatopathy in rats	2
Fucoxanthin suppresses OxLDL-induced inflammation via activation of Nrf2 and inhibition of NF-κB signaling	2
Shikonin shows retinoprotective effects in diabetic rats via modulating the Nrf2/HO-1 and NF-κB signaling pathways	2
Phloretin-induced suppression of oxidative and nitrosative stress attenuates doxorubicin-induced cardiotoxicity in rats	2
Identification of potential biomarkers and pathways related to major depressive disorder by integrated bioinformatic analysis and experimental validation	2
Antimicrobial, antibiofilm, angiogenesis, anti-inflammatory, and wound healing activities of zinc nanoparticles green synthesized using Ferula macrecolea extract	2
Midkine ameliorates LPS-induced apoptosis of airway smooth muscle cells via the Notch2 pathway	2
Molluscicidal activities of green-synthesized Alstonia congensis silver nanoparticles	2
Ardisia gigantifolia ethanolic extract inhibits cell proliferation and targets cancer stem cells in gastric cancer	2
Cardioprotective effects of Pinus eldarica bark extract on adrenaline-induced myocardial infarction in rats	2
Naringin attenuates oxidative stress, inflammation, apoptosis, and oxidative DNA damage in acrylamide-induced nephrotoxicity in rats	2
Therapeutic effects of Coriandrum sativum extracts: A review	2
Pachymic acid exerts antitumor activities by modulating the Wnt/β-catenin signaling pathway via targeting PTP1B	2
Chemical composition and wound healing potential of Lindernia ruellioides (Colsmann) Pennell from Mizoram, India	2
Anti-leishmanial, immunomodulatory and anti-oxidative activity of quercetin against cutaneous leishmaniasis caused by Leishmania major	2
Alantolactone mitigates thioacetamide-induced liver fibrosis in mice by inhibiting TLR4/MyD88/NF-κB axis	2
Hexadecanoic acid-enriched extract of Halymenia durvillei induces apoptotic and autophagic death of human triple-negative breast cancer cells by upregulating ER stress	2
Capsosiphon fulvescens suppresses LPS-stimulated inflammatory responses by suppressing TLR4/NF-κB activation in RAW264.7 murine macrophages	2
Coumarin-loaded chitosan nanoparticles alleviate high-fructose diet-induced diabetes by modulating insulin and eNOS/NO signaling	2
Rosmarinic acid improves tracheal smooth muscle responsiveness and lung pathological changes in ovalbumin-sensitized rats	2
Sinomenine exerts cardioprotective effects in a rat model of myocardial ischemia/reperfusion injury	2
Neuroprotective effect of liraglutide and memantine in a rat model of Alzheimer’s disease	2
Anti-angiogenesis and anti-inflammatory effects of Moringa oleifera leaf extract in the early stages of streptozotocin-induced diabetic nephropathy in rats	1
Lagerstroemia indica methanolic extract alleviates CCl4-induced liver toxicity via modulation of Nrf2 signaling pathway in rats	1
Modulatory effect of D-pinitol on bleomycin-induced pulmonary fibrosis in rats	1
In vitro anti-melanoma effect of polyphenolic compounds	1
Oleuropein alleviates sepsis-induced acute lung injury via the AMPK/Nrf-2/HO-1 signaling	1
Cardioprotective effect of bioassay–guided fractions of Cleome viscosa methanolic extract in streptozotocin–induced diabetic rats	1
Pyronaridine combined with diminazene aceturate inhibits Babesia in vitro and in vivo	1
Melatonin alleviates oxidative stress, inflammation, apoptosis, and DNA damage in acrylamide–induced nephrotoxicity in rats	1
Therapeutic effects of crocin: A review of recent studies	1
Senna petersiana inhibits key digestive enzymes and modulates dysfunctional enzyme activities in oxidative pancreatic injury	1
Antimicrobial activities of Acacia genus	1
Schisandrae Fructus oil-induced elevation in serum triglyceride and lipoprotein concentrations associated with physiologic hepatomegaly in mice	1
Catalpa bignonioides extract improves exercise performance through regulation of growth and metabolism in skeletal muscles	1
Luteolin attenuates diabetic nephropathy via inhibition of metalloenzymes in rats	1
Protein extract of kenaf seed exhibits anticoagulant, antiplatelet and antioxidant activities	1
Flavone improves liver damage in nicotine-exposed rats via the Nrf2/HO-1 pathway	1
Foeniculum vulgare Mill. inhibits lipopolysaccharide-induced microglia activation and ameliorates neuroinflammation-mediated behavioral deficits in mice	1
Verbascum thapsus L. ethanol fraction mitigates CCl4-induced hepatic damage via inhibition of TNFα-NF-κB signaling and oxidative stress in rats	1
Zinc oxide nanoparticles accelerate the healing of methicillin-resistant Staphylococcus aureus (MRSA)-infected wounds in rabbits	1
ClpB chaperone as a promising target for antimicrobial therapy: A narrative review	1
Anti–melanogenic properties of FBCC–EP850 derived from Carex pumila Thunb	1
Analgesic-like activity of perillyl acetate	1
Gum resin extract of Boswellia serrata attenuates lipopolysaccharide-induced inflammation and oxidative damage in hepatic and renal tissues of rats	1
Naringenin suppresses NLRP3 inflammasome activation via the mRNA-208a signaling pathway in isoproterenol-induced myocardial infarction	1
Glinus lotoides ethanolic extract alleviates LPS-induced anxiety and depression-like behavior by modulating antioxidant and inflammatory biomarkers in rats	1
Inhibition mechanisms of secretome proteins from Paenibacillus polymyxa Kp10 and Lactococcus lactis Gh1 against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus	1
Cardiovascular protective properties of gastrodin	1
Myricetin alleviates ovalbumin-induced allergic rhinitis in mice by regulating Th1/Th2 balance	1
Extract of Codiaeum luzonicum Merr. overcomes multidrug resistance in human colon cancer cells by modulating P-glycoprotein	1
Levisticum officinale extract protects against CCl4-induced hepatotoxicity through anti-inflammatory, anti-fibrotic, and antioxidant properties in rats	1
Salacia fruticosa methanol extract pretreatment attenuates scopolamine-induced cognitive decline and Alzheimer's disease-related pathology in zebrafish	1
Anti-tumor effects and cellular mechanisms of Pistacia atlantica methanolic extract against Ehrlich solid tumor in mice	1
Polyphenol-rich extract from Wisteria floribunda (Willd.) DC. flowers promotes osteoblast differentiation and bone formation by modulating the mTOR pathway	1
Hydroxysafflor yellow A protects against thioacetamide-induced liver fibrosis in rats via suppressing proinflammatory/fibrogenic mediators and promoting hepatic stellate cell senescence and apoptosis	1
Syringic acid induces cancer cell death in the presence of Cu (II) ions via pro-oxidant activity	1
Barrientosiimonas humi ethyl acetate extract exerts cytotoxicity against MCF-7 and MDA-MB-231 cells via induction of apoptosis and cell cycle arrest	1
Gracilaria chorda-derived compounds improve lipid metabolism and insulin sensitivity in 3T3-L1 adipocytes and high-fat diet-induced obese zebrafish larvae	1
Calorie restriction potentiates epigallocatechin-3-gallate-mediated Nrf2 activation in hepatocytes of aged rats	1
Hydrangea serrata extract exerts tumor inhibitory activity against hepatocellular carcinoma HepG2 cells via inducing p27/CDK2-mediated cell cycle arrest and apoptosis	1
Salsola imbricata attenuates type 2 diabetes mellitus in rats by regulating oxidative stress and insulin signaling	1
Therapeutic potential of Calotropis gigantea extract against invasive pulmonary aspergillosis	1
Antibacterial, antibiofilm, and wound healing activities of Piper longum root in multidrug-resistant Staphylococcus aureus infected mice	1
Agmatine ameliorates diabetes type 2-induced nephropathy in rats	1
Ligustroside derived from Ligustrum japonicum inhibits melanogenesis via blocking the MAPK and PKA/CREB signaling pathways	1
Humulus japonicus extract alleviates oxidative stress and apoptosis in 6-hydroxydopamine-induced PC12 cells	1

Dieckol isolated from Eisenia bicyclis extract suppresses RANKL-induced osteoclastogenesis in murine RAW 264.7 cells	1
Betulin protects against isoproterenol-induced myocardial injury by inhibiting NF-κB signaling and attenuating cardiac inflammation and oxidative stress in rats	1
Hepatoprotective effect of date palm fruit extract against doxorubicin intoxication in Wistar rats	1