OOIR: Observatory of International Research

Papers

(The H4-Index of Biomedicines is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Importance of Electrode Selection and Number in Reconstructing Standard Twelve Lead Electrocardiograms	319
The Safety and Efficacy of Dietary Epigallocatechin Gallate Supplementation for the Management of Obesity and Non-Alcoholic Fatty Liver Disease: Recent Updates	269
Nerve Enlargement in Patients with INF2 Variants Causing Peripheral Neuropathy and Focal Segmental Glomerulosclerosis	239
Identifying MTHFD1 and LGALS4 as Potential Therapeutic Targets in Prostate Cancer Through Multi-Omics Mendelian Randomization Analysis	186
Calpain Small Subunit Mediated Secretion of Galectin-3 Regulates Traction Stress	168
Long-Term Efficacy of Carboxymethyl-Chitosan in Advanced Knee Osteoarthritis: A Twelve-Month Follow-Up Study on Non-Responders to Hyaluronic Acid	164
Well-Preserved Urinary Bladder Anatomy in Rats After Minimally Invasive Surgery	156
Neuroanatomical Insights: Convergence and Divergence of Tinnitus with Normal or Mild Hearing Loss	156
Assessment of IL-6 Pathway Inhibition in Gastrointestinal Behçet’s Disease from Immunological and Clinical Perspectives	152
Gut Microbiota as Emerging Players in the Development of Alcohol-Related Liver Disease	150
Modeling of Blood Flow Dynamics in Rat Somatosensory Cortex	148
Advances in Immunotherapy and Targeted Therapy of Malignant Melanoma	146
miRNAs and Hematological Markers in Non-Alcoholic Fatty Liver Disease—A New Diagnostic Path?	143
Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs	139
Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications	133
A Biopsychosocial Overview of Speech Disorders: Neuroanatomical, Genetic, and Environmental Insights	131
Toxicity Associated with Pembrolizumab Monotherapy in Patients with Gastrointestinal Cancers: A Systematic Review of Clinical Trials	129
Palm Tocotrienol Activates the Wnt3a/β-Catenin Signaling Pathway, Protecting MC3T3-E1 Osteoblasts from Cellular Damage Caused by Dexamethasone and Promoting Bone Formation	126
Advancing Hydrogel-Based 3D Cell Culture Systems: Histological Image Analysis and AI-Driven Filament Characterization	123
Functionalized GelMA/CMCS Composite Hydrogel Incorporating Magnesium Phosphate Cement for Bone Regeneration	120
Advancing Atrial Fibrillation Research: The Role of Animal Models, Emerging Technologies and Translational Challenges	115
Sensory Dysfunction in ALS and Other Motor Neuron Diseases: Clinical Relevance, Histopathology, Neurophysiology, and Insights from Neuroimaging	114
Reversing Pathology in an Aggravated Fabry Mouse Model Using Low-Dose Engineered Human Alpha-Galactosidase A AAV Gene Therapy	109
Applying Wearable Sensors and Machine Learning to the Diagnostic Challenge of Distinguishing Parkinson’s Disease from Other Forms of Parkinsonism	104
Acid Sphingomyelinase and Ceramide Signaling Pathway Mediates Nicotine-Induced NLRP3 Inflammasome Activation and Podocyte Injury	100

Urinary Metabolic Profiling During Epileptogenesis in Rat Model of Lithium–Pilocarpine-Induced Temporal Lobe Epilepsy	98
The Dentin Microbiome: A Metatranscriptomic Evaluation of Caries-Associated Bacteria	94
Insights into the Correlation and Immune Crosstalk Between COVID-19 and Sjögren’s Syndrome Keratoconjunctivitis Sicca via Weighted Gene Coexpression Network Analysis and Machine Learning	93
Sonidegib Inhibits the Adhesion of Acute Myeloid Leukemia to the Bone Marrow in Hypoxia: An Optical Tweezer Study	92
Blood Pressure Regulation Evolved from Basic Homeostatic Components	92
Effectiveness of Humidified High Flow Nasal Cannula Versus Continuous Nasal Positive Airway Pressure in Managing Respiratory Failure in Preterm Infants: An Emergency Department Study	91
Personalized Nutrition in Chronic Kidney Disease	91
Structured Cardiac Assessment and Treatment Following Exacerbations of COPD (SCATECOPD): A Pilot Randomised Controlled Trial	89
A2-Astrocyte Activation by Short-Term Hypoxia Rescues α-Synuclein Pre-Formed-Fibril-Induced Neuronal Cell Death	89
White Matter Microstructural Abnormalities in Children with Familial vs. Non-Familial Attention-Deficit/Hyperactivity Disorder (ADHD)	88
Serum Biomarkers in Patent Ductus Arteriosus in Preterm Infants: A Narrative Review	87
Novel Insights into CKMB, Myoglobin, and Troponin I Levels as Predictors of COVID-19 Severity and Hospitalization Outcomes	86
Cortical Origin-Dependent Metabolic and Molecular Heterogeneity in Gliomas: Insights from 18F-FET PET	85
Non-Invasive Assessment of Vascular Damage Through Pulse Wave Velocity and Superb Microvascular Imaging in Pre-Dialysis Patients	84
Three-Dimensional Speckle-Tracking Echocardiography-Derived Left Ventricular Global Longitudinal Strain and Mitral Annular Plane Systolic Excursion Are Associated in Healthy Adults—Insights from the M	82
Effectiveness of Generative Artificial Intelligence-Driven Responses to Patient Concerns in Long-Term Opioid Therapy: Cross-Model Assessment	80
Optimization of Nutrition after Brain Injury: Mechanistic and Therapeutic Considerations	78
Rapid In Vivo Screening of Monoclonal Antibody Cocktails Using Hydrodynamic Delivery of DNA-Encoded Modified Antibodies	78
Magnolol Triggers Caspase-Mediated Apoptotic Cell Death in Human Oral Cancer Cells through JNK1/2 and p38 Pathways	77
Trem2 Enhances Demyelination in the Csf1r+/− Mouse Model of Leukoencephalopathy	77
TGFβ1 Induces Senescence and Attenuated VEGF Production in Retinal Pericytes	76
Infection Risk in Patients with Dermatomyositis Associated with Anti-MDA5 Antibodies: A Historical Cohort Study	76
Real-World Endoscopic and Histologic Outcomes in Ulcerative Colitis Patients: A Retrospective Cohort Study	76
Dental-Pulp Stem Cells as a Therapeutic Strategy for Ischemic Stroke	75
Neuropsychological Assessment in Patients with Traumatic Brain Injury: A Comprehensive Review with Clinical Recommendations	75
Shrimp Lipids Inhibit Migration, Epithelial–Mesenchymal Transition, and Cancer Stem Cells via Akt/mTOR/c-Myc Pathway Suppression	75
Dbf4-Cdc7 (DDK) Inhibitor PHA-767491 Displays Potent Anti-Proliferative Effects via Crosstalk with the CDK2-RB-E2F Pathway	74
miR-195-5p Regulates Tight Junctions Expression via Claudin-2 Downregulation in Ulcerative Colitis	74
Metabolic Fingerprinting for the Diagnosis of Clinically Similar Long COVID and Fibromyalgia Using a Portable FT-MIR Spectroscopic Combined with Chemometrics	73
Comprehensive Analysis of Disulfidptosis-Related LncRNAs in Molecular Classification, Immune Microenvironment Characterization and Prognosis of Gastric Cancer	73
Improved Protocol to Study Osteoblast and Adipocyte Differentiation Balance	73
Asoprisnil as a Novel Ligand Interacting with Stress-Associated Glucocorticoid Receptor	72
Synthesis, In Silico Study, and Anti-Cancer Activity of Thiosemicarbazone Derivatives	72
Is a High HDL-Cholesterol Level Always Beneficial?	72
Biological Activity Evaluation and In Silico Studies of Polyprenylated Benzophenones from Garcinia celebica	71
Genetic Variations of the Vitamin D Metabolic Pathway and COVID-19 Susceptibility and Severity: Current Understanding and Existing Evidence	71
Checkpoint Inhibitor-Induced Colitis: An Update	71
The Identification of Prohibitin in the Rat Heart Mitochondria in Heart Failure	69
Pittsburgh Sleep Quality Index (PSQI) Changes in Virologically Suppressed People Living with HIVSwitching to Long-Acting Cabotegravir and Rilpivirine	69
The Relationship between the Expression of GATA4 and GATA6 with the Clinical Characteristics and Prognosis of Resectable Pancreatic Adenocarcinoma	68
YAP/ACSL4 Pathway-Mediated Ferroptosis Promotes Renal Fibrosis in the Presence of Kidney Stones	67
Post-Bariatric Hypoglycemia Is Associated with Endothelial Dysfunction and Increased Oxidative Stress	67