OOIR: Observatory of International Research

Papers

(The median citation count of Bioimpacts is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Inhibitory effect of miR342 on the progression of triple-negative breast cancer cells in vitro and in the mice model	48
Photoplethysmography based non-invasive blood glucose estimation using systolic-diastolic framing MFCC features and machine learning regression	33
The role of artificial intelligence in enhancing breast cancer screening and diagnosis: A review of current advances	29
A cancer diagnosis transformer model based on medical IoT data for clinical measurements in predictive care systems	27
Smart IoT-driven biosensors for EEG-based driving fatigue detection: A CNN-XGBoost model enhancing healthcare quality	25
Advances in nanomaterials for precision drug delivery: Insights into pharmacokinetics and toxicity	20
Molecular dynamics simulation in tissue engineering	19
Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems	15
Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells	14
Exosomes: Redefining intercellular communication and the future of translational medicine	14
Targeting long non-coding RNAs as new modulators in anti-EGFR resistance mechanisms	13
Investigating the function and targeting of MET protein as an oncogene kinase in pancreatic ductal adenocarcinoma: A microarray data integration	13
Cell-imprinted substrates as biomimetic platforms for osteoarthritis modeling with mesenchymal stem cells	13
Thalidomide augments maturation and T helper 1-inducing capacity of monocyte-derived dendritic cells in vitro	12
Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy	12
Spirulina: A promising opportunity to overcome neuropathic pain challenges in chronic kidney disease patients	11
Autophagy stimulation influenced the angiogenesis and metastasis behavior of human triple-negative breast cancer cells	11
MicroRNA-372-3p impairs fatty acid metabolism in hepatocellular carcinoma cells by targeting CPT1A and ACSL4	10
Potential role of epidermal growth factor receptors (EGFR) signaling in the pathogenesis and management of hepatocellular carcinoma	10
The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach	10
Targeting hypoxia-inducible factor 1 alpha augments synergistic effects of chemo/immunotherapy via modulating tumor microenvironment in a breast cancer mouse model	9
Anti-Alzheimer effects of the newly synthesized cationic compounds as multi-target dual hAChE/hBuChE inhibitor: An in silico, in vitro, and in vivo approach	9
Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells	9
Homozygous mutation in CSF1R causes brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS)	9
Regulation of cell fate by cell imprinting approach in vitro	8

Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach	8
Biosynthesis of sulfur quantum dots and cerium oxide nanoparticles for bioimaging and reactive oxygen species modulation in Y79 retinoblastoma cancer cells	7
The effects of Fe₂O₃ nanoparticles on catalytic function of human acetylcholinesterase: size and concentration role	7
Type 2 diabetes mellitus induced autophagic response within pulmonary tissue in the rat model	7
Biologically inspired laccase-mimicking OVA-Cu complex for degradation of organic dye pollutant: Artificial neural network modeling and optimization	7
Enantioselective analysis of metoprolol in plasma of hypertensive patients undergoing long-term therapy: Insights for personalized medicine	7
Correction: Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers	6
Systemic nitric oxide metabolites and the chance of pre-diabetes regression to normoglycemia: A 9-year cohort study	6
Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers	6
Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds	6
The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration	6
Deciphering the role of classical oestrogen receptor in insulin resistance and type 2 diabetes mellitus: From molecular mechanism to clinical evidence	6
Differentiation of human endometrial stem cells encapsulated in alginate hydrogel into oocyte-like cells	6
Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6)	6
Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models	6
Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance	6
COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis	6
Mode of binding, kinetic and thermodynamic properties of a lipid-like drug (Fingolimod) interacting with Human Serum Albumin	6
Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect	6
The effect of Sertoli cell exosomes on spermatogonia stem cells differentiation	6
Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model	5
Advances in nanocarrier-mediated delivery of chrysin: Enhancing solubility, bioavailability, and anticancer efficacy	5
Growth and invasion inhibition of T47D ductal carcinoma cells by the association of docetaxel with a bioactive agent in neutral nanosuspension	5
Mesenchymal stem cells as a therapeutic strategy to combat oxidative stress-mediated neuropathic pain	5
Nanobody-functionalized liposomal doxorubicin: A novel strategy for angiogenesis suppression via VEGFR2 targeting	5
Preparation and evaluation of a polycaprolactone/chitosan/propolis fibrous nanocomposite scaffold as a tissue engineering skin substitute	5
microRNAs shuttled by mesenchymal stromal cell-derived exosomes in coronary artery disease: A systematic review of preclinical studies	5
Immune-modulatory biomimetic nanoparticles: Advances in design, mechanisms, and nanomedicine applications	5
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective	5
Optimized cutaneous delivery of anti-wrinkle dipeptide KT via molecular modification: Preformulation, permeation, and the importance of conjugate chain length	5
Changing the daily injection of glatiramer acetate to a monthly long acting product through designing polyester-based polymeric microspheres	4
Exosomes in neuron-glia communication: A review on neurodegeneration	4
University rankings: Time to reconsider	4
Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis	4
Recent advancement in polymeric nanoparticles for oral chemotherapy: Transforming cancer treatment	4
Bone marrow mesenchymal stem cells improve cognitive impairments induced by methamphetamine in rats and reduce relapse	4
Stimuli-responsive synthesis of silver nanoparticles applying green and chemical reduction approaches	4
Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer	4
A subspace learning aided matrix factorization for drug repurposing	4
Effect of microRNA-141-3p, E2F3, CDK3, and KAT2B overexpression on histologic tumor grade and metastasis status in untreated breast cancer tissues	4
Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses	4
Cancer treatment comes to age: from one-size-fits-all to next-generation sequencing (NGS) technologies	4
Resolvin D1 alleviates lipopolysaccharide-induced in vitro corneal inflammation by modulating macrophage polarization through upregulation of c-Fos expre	4
CFP10–loaded PLGA nanoparticles as a booster vaccine confer protective immunity against Mycobacterium bovis	4
Designing of multi-epitope vaccine against Varicella zoster virus (VZV) using immunoinformatics and structural analysis: In silico study	4
SBFI-26 enhances apoptosis in docetaxel-treated triple-negative breast cancer cells by increasing ROS levels	4
Retinoic acid-releasing scaffold based on chitosan hydrogel and testis decellular plates	3
Comparative molecular docking and toxicity between carbon-capped metal oxide nanoparticles and standard drugs in cancer and bacterial infections	3
Effect of parenteral L-carnitine in hospitalized patients with moderate to severe COVID-19: A randomized double-blind clinical trial	3
The role of bioinformatics algorithms in modern biopharmaceutical design: Progress, challenges, and future perspectives	3

CAR-T cell therapy as an approach for pediatric hematological malignancies in regenerative therapy: Current status and clinical outcomes	3
DNA methylation as a potential mediator between environmental pollutants and osteoporosis; a current hypothesis	3
A new method for early diagnosis and treatment of meniscus injury of knee joint in student physical fitness tests based on deep learning method	3
IgY-mediated protection against Vibrio cholerae infection: Efficacy of avian antibodies targeting a chimeric recombinant protein	3
A potential mechanism for tau protein modulating in schizophrenia with transcranial direct current stimulation intervention: A randomized controlled trial	3
Oil-in-water nanoemulsions for glaucoma treatment: An insight into the latest trends	3
An efficient hybrid filter-wrapper method based on improved Harris Hawks optimization for feature selection	3
Ambivalent roles of miRNAs in cancer development via modulating tumor-associated innate immune cells	3
Artesunate reduces sepsis-mediated acute lung injury in a SIRT1-dependent manner	3
In-silico based discovery of potential Keap1 inhibitors using the strategies of pharmacophore screening, molecular docking, and MD simulation studies	3
Performance of protein N linear epitopes in serodiagnosis of COVID-19 infection	3
Exaggerating the risks of vaccination is a dangerous health threat	3
New approach to generating of human monoclonal antibodies specific to the proteolytic domain of botulinum neurotoxin A	3
Predicting drug protein interactions based on improved support vector data description in unbalanced data	3
Identification and characterization of antibacterial peptides produced by Lactobacillus plantarum 1407	3
Simultaneous suppression of miR-21 and restoration of miR-145 in gastric cancer cells; a promising strategy for inhibition of cell proliferation and migration	3
Hierarchical classification of anterior cruciate ligament using deep learning for athletes healthcare	3
The role of tumor microenvironment and self-organization in cancer progression: Key insights for therapeutic development	2
Burn wound healing using adipose-derived mesenchymal stem cells and manganese nanoparticles in polycaprolactone/gelatin electrospun nanofibers in rats	2
An update on a technical method of cartilage decellularization: (a physical-based protocol)	2
Targeted therapy for liver cancer: Current status and future directions	2
Celastrol overcomes 5-fluorouracil resistance in osteosarcoma cells through p53-mediated apoptotic pathway modulation and P-glycoprotein inhibition: A comprehensive mechanistic study	2
Fabrication of mesoporous silica nanoparticles for targeted delivery of sunitinib to ovarian cancer cells	2
The emergence of advanced technologies in the pharmacy profession and the need for education: The case of point-of-care sensing systems and 3D printing of pharmaceuticals	2
Artificial intelligence–guided nanoparticle design for advanced targeted drug delivery	2
Functionality of immune cells in COVID-19 infection: development of cell-based therapeutics	2
Stabilization of Hoogsteen H-bonds in G-quartet sheets by coordinated K⁺ ion for enhanced efficiency in guanine-rich DNA nanomotor	2
Static electromagnetic field and recombinant human fibroblasts encoding miR-451 and miR-16 increased cell trans-differentiation to CD⁷¹⁺ and CD^235a+ erythroid like progenitor	2
Bibliometric study of BioImpacts using a technological impact approach	2
Material synthesis and design optimization of biomaterials for biomedical implant applications	2
Silibinin exhibits anti-tumor effects in a breast cancer stem cell model by targeting stemness and induction of differentiation and apoptosis	2
SARS-CoV-2 vaccine-triggered autoimmunity: Molecular mimicry and/or bystander activation of the immune system	2
Organoid-engineered neurovascular units for drug discovery and neurodegeneration research	2
Kopexil vs minoxidil: In vivo comparative study on hair growth, hair growth promoting factors and toxicity	2
The effectiveness of antioxidant agents in delaying progression of diabetic nephropathy: A systematic review of randomized controlled trials	2
Vandetanib alters the tumoricidal capacity of human breast cancer stem cells via inhibiting vasculogenic capacity	2
Safety and efficacy of extracellular vesicles in individuals with cancer; A systematic review	2
Poly (acrylic acid)/tricalcium phosphate nanoparticles scaffold enriched with exosomes for cell-free therapy in bone tissue engineering: An in vivo evaluation	2
Reduced inflammation following human endometrial stromal/stem cell injection into male Wistar rats with cisplatin-induced acute kidney injury	2
Comparison the therapeutic effects of bone marrow CD144⁺ endothelial cells and CD146⁺ mesenchymal stem cells in POF rats	2
Exosomes-derived mesenchymal stem cells in corneal regeneration: Properties and challenges	2
Regulation of ubiquitin-proteasome system and its relative pathways in pancreatic adenocarcinoma	2
Chondrogenic Potential of PMSCs Cultured on Chondroitin Sulfate/Gelatin -Modified DBM Scaffold	2
Hybrid deep learning models for text-based identification of gene-disease associations	2
Uncovering the anticancer effects of Bhallataka Taila in lung cancer: A metabolomic and network pharmacology approach	2
Micro-extraction, pre-concentration, and microfluidic-based separation of organophosphate insecticides followed by the miniaturized electrochemical detection system	2
Unlocking the potential of lumateperone and novel anti-psychotics for schizophrenia	2
Recent innovations in nanomedicine and nano-based techniques for the treatment of breast cancer	2
Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives	2
Chemo-immune cell therapy by intratumoral injection of adoptive NK cells with capecitabine in gastric cancer xenograft model	2
Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer	2
The implications of pharmacogenomics in oncology	2
Promising leads against lung cancer from the plants in Lamiaceae family	2
Allogeneic Treg-derived artificial vesicles: A promising therapeutic modality for multiple sclerosis	2