OOIR: Observatory of International Research

Papers

(The median citation count of Bioimpacts is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Overview of dendritic cells subsets and their involvement in immune-related pathological disease	32
Mesenchymal stem cells as a therapeutic strategy to combat oxidative stress-mediated neuropathic pain	25
The active lung microbiota landscape of COVID-19 patients through the metatranscriptome data analysis	17
Advances in nanomaterials for precision drug delivery: Insights into pharmacokinetics and toxicity	17
Retinoic acid-releasing scaffold based on chitosan hydrogel and testis decellular plates	16
Epithelial cells/progenitor cells in developing human lower respiratory tract: Characterization and transplantation to rat model of pulmonary injury	16
Advances in nanocarrier-mediated delivery of chrysin: Enhancing solubility, bioavailability, and anticancer efficacy	15
A potential mechanism for tau protein modulating in schizophrenia with transcranial direct current stimulation intervention: A randomized controlled trial	12
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective	12
Role of nanostructured lipid carriers in the expression alterations of ATP-binding cassette transporter genes in fluconazole-resistant Candida glabrata	10
Effect of α-pinene and thymoquinone on the differentiation of bone marrow mesenchymal stem cells into neuroprogenitor cells	10
Inhibitory effect of miR342 on the progression of triple-negative breast cancer cells in vitro and in the mice model	9
Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6)	9
A novel imidazo[1,2-a]pyridine derivative and its co-administration with curcumin exert anti-inflammatory effects by modulating the STAT3/NF-κB/iNOS/COX-2 signaling pathway in breast and ovarian cance	8
Smart IoT-driven biosensors for EEG-based driving fatigue detection: A CNN-XGBoost model enhancing healthcare quality	8
Growth and invasion inhibition of T47D ductal carcinoma cells by the association of docetaxel with a bioactive agent in neutral nanosuspension	8
A comprehensive review on alpha-lipoic acid delivery by nanoparticles	7
Essential role of CD38 in platelet aggregation through the PKC- mediated internalization and activation	7
Protective effects of limb remote ischemic per-conditioning on the heart injury induced by renal ischemic-reperfusion through the interaction of the apelin with the RAS/iNOS pathway	6
The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration	6
Molecular dynamics simulation in tissue engineering	6
Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect	6
Recent advances in electrochemical strategies for bacteria detection	6
Thiazolo-pyridopyrimidines: An in silico evaluation as a lead for CDK4/6 inhibition, synthesis and cytotoxicity screening against breast cancer cell lines	6
Enhanced reno-protective effects of CHIR99021 modified mesenchymal stem cells against rat acute kidney injury model	6

Recent advancements in cell-based models for auditory disorders	5
A promising breakthrough in pancreatic cancer research: The potential of spheroids as 3D models	5
Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds	5
Cloth-based microfluidic devices integrated onto the patch as wearable colorimetric sensors for simultaneous sweat analysis	4
The oncolytic activity of Clostridium novyi nontoxic spores in breast cancer	4
Synergism of d-limonene and temozolomide on migratory and apoptotic behaviors of human glioblastoma cell lines	4
A cancer diagnosis transformer model based on medical IoT data for clinical measurements in predictive care systems	4
Evaluation of specific lncRNAs, miRNAs, and mRNAs in different groups of prostate cancer	4
Exosomes as versatile nanoscaled biocompartments in cancer therapy and/or resistance	4
Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models	4
Preparation and evaluation of a polycaprolactone/chitosan/propolis fibrous nanocomposite scaffold as a tissue engineering skin substitute	4
Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems	4
CRISPR-Cas9 in basic and translational aspects of cancer therapy	3
The diagnostic and prognostic value of C1orf174 in colorectal cancer	3
Enhanced growth and differentiation of neural stem cells on alginate/collagen/reduced graphene oxide composite hydrogel incorporated with lithium chloride	3
Promising leads against lung cancer from the plants in Lamiaceae family	3
Multi spectroscopic and molecular simulation studies of propyl acridone binding to calf thymus DNA in the presence of electromagnetic force	3
Comparative modeling of the mitral valve in normal and prolapse conditions	3
STAT signaling pathways in immune cells and their associated mechanisms in cancer pathogenesis	3
Bibliometric study of BioImpacts using a technological impact approach	3
Design and implementation of a lab-on-a-chip for assisted reproductive technologies	3
Effect of Honokiol on culture time and survival of Alzheimer’s disease iPSC-derived neurons	3
Enhanced control of bioactivity of tissue plasminogen activator (tPA) through domain-directed enzymatic oxidation of terminal galactose	3
Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells	3
Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model	3
To detect potential pathways and target genes in infantile Pompe patients using computational analysis	3
Bone marrow mesenchymal stem cells improve cognitive impairments induced by methamphetamine in rats and reduce relapse	2
Homozygous mutation in CSF1R causes brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS)	2
Role of Toll-like receptors in exosome biogenesis and angiogenesis capacity	2
Mesenchymal stromal cells therapy alone does not lead to the complete restoration of the skin parameters in diabetic foot patients within a 3-year follow-up period	2
Repairing rat calvarial defects by adipose mesenchymal stem cells and novel freeze-dried three-dimensional nanofibrous scaffolds	2
Hollow pollen grains as scaffolding building blocks in bone tissue engineering	2
Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like receptor ligands	2
Platinum(IV) compounds as potential drugs: a quantitative structure-activity relationship study	2
Simulation and fabrication of an integrating well-aligned silicon nanowires substrate for trapping circulating tumor cells labeled with Fe₃O₄ nanoparticles in a microfluidic devi	2
Drug self-delivery systems: A comprehensive review on small molecule nanodrugs	2
Optimized cutaneous delivery of anti-wrinkle dipeptide KT via molecular modification: Preformulation, permeation, and the importance of conjugate chain length	2
Opioid overdose, interventions, and challenges	2
COVID-19: Artificial sputum, respiratory obstruction method and screening of pyolitic and antihypoxic drugs	2
Evaluation of poly (lactic-co-glycolic acid) nanoparticles to improve the therapeutic efficacy of paclitaxel in breast cancer	2
Changing the daily injection of glatiramer acetate to a monthly long acting product through designing polyester-based polymeric microspheres	2
Vandetanib alters the tumoricidal capacity of human breast cancer stem cells via inhibiting vasculogenic capacity	2
Evaluating the presence of deregulated tumoral onco-microRNAs in serum-derived exosomes of gastric cancer patients as noninvasive diagnostic biomarkers	2
Regulation of ubiquitin-proteasome system and its relative pathways in pancreatic adenocarcinoma	2
CRISPRi-mediated knock-down of PRDM1/BLIMP1 programs central memory differentiation in ex vivo-expanded human T cells	2
Autophagy induced macrophages by α-alumina(α-AL2O3) conjugated cysteine peptidase, enhances the cytotoxic activity of CD8+ T lymphocytes against Leishmania major	2
A procedure for DNA methylation assessment in osteoporosis-related gene promoters of umbilical cord blood: A study on the Prospective Epidemiological Research Studies in Iran (PERSIAN) birth cohort	2
Fabrication of mesoporous silica nanoparticles for targeted delivery of sunitinib to ovarian cancer cells	2
Osteoblastic cell response to Al₂O₃-Ti composites as bone implant materials	2
Comparison the therapeutic effects of bone marrow CD144⁺ endothelial cells and CD146⁺ mesenchymal stem cells in POF rats	1

Targeting hypoxia-inducible factor 1 alpha augments synergistic effects of chemo/immunotherapy via modulating tumor microenvironment in a breast cancer mouse model	1
Chitosan nanoparticle-mediated effect of antimiRNA-324-5p on decreasing the ovarian cancer cell proliferation by regulation of GLI1 expression	1
Podocyte-specific proteins in urinary extracellular vesicles of patients with IgA nephropathy: Vasorin and ceruloplasmin	1
Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer	1
Identification and characterization of antibacterial peptides produced by Lactobacillus plantarum 1407	1
Bioscaffolds of graphene based-polymeric hybrid materials for myocardial tissue engineering	1
Injectable thermosensitive chitosan/gelatin hydrogel for dental pulp stem cells proliferation and differentiation	1
Synthesis, characterization, and evaluation of pH-sensitive doxorubicin-loaded functionalized graphene oxide in osteosarcoma cells	1
Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy	1
Benchmarking different docking protocols for predicting the binding poses of ligands complexed with cyclooxygenase enzymes and screening chemical libraries	1
Lactiplantibacillus plantarum exerts anticancer effects and increase the chemosensitivity of 5-fluorouracil against oral cancer cells in vitro	1
Static electromagnetic field and recombinant human fibroblasts encoding miR-451 and miR-16 increased cell trans-differentiation to CD⁷¹⁺ and CD^235a+ erythroid like progenitor	1
The implications of pharmacogenomics in oncology	1
Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers	1
Protective effects of sumatriptan against optic nerve injury in rats via modulation of kynurenine pathway, oxidative stress and apoptosis	1
CFP10–loaded PLGA nanoparticles as a booster vaccine confer protective immunity against Mycobacterium bovis	1
Automatic classification of Giardia infection from stool microscopic images using deep neural networks	1
Efficient conjugation of anti-HBsAg antibody to modified core-shell magnetic nanoparticles (Fe₃O₄@SiO₂/NH₂)	1
CRISPR-based gene editing in plants: Focus on reagents and their delivery tools	1
miR-1290 contributes to oncogenesis and angiogenesis via targeting of THBS1, DKK3 and, SCAI	1
The synergistic impact of sleep duration and obesity on metabolic syndrome risk: exploring the role of microRNAs	1
Assessment of the biocompatibility and biodistribution of fluorescent oleic acid capped ZnSe/CdS/ core shell quantum dots after intravenous injection in Balb/c mice	1
The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach	1
Enhanced characterization of beta cell mass in a Tg(Pdx1-GFP) mouse model	1
Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells	1
Design and computational analysis of an effective multi-epitope vaccine candidate using subunit B of cholera toxin as a build-in adjuvant against urinary tract infections	1
Exosomes in neuron-glia communication: A review on neurodegeneration	1
Towards modeling of phonation and its recovery in unilateral vocal fold paralysis by fluid-structure interaction	1
Targeting long non-coding RNAs as new modulators in anti-EGFR resistance mechanisms	1
Synthesis, characterization and hepatoprotective effect of silymarin phytosome nanoparticles on ethanol-induced hepatotoxicity in rats	1
Expression of functional eGFP-fused antigen-binding fragment of ranibizumab in Pichia pastoris	1
Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses	1
Poly (acrylic acid)/tricalcium phosphate nanoparticles scaffold enriched with exosomes for cell-free therapy in bone tissue engineering: An in vivo evaluation	1
Targeted gene delivery to the brain using CDX-modified chitosan nanoparticles	1
Cancer treatment comes to age: from one-size-fits-all to next-generation sequencing (NGS) technologies	1
Abuse potential of fentanyl and fentanyl analogues	1
Effectiveness of dolutegravir in moderate severity COVID-19 patients: A single-center, randomized, double-blind, placebo-controlled trial	1
Thalidomide augments maturation and T helper 1-inducing capacity of monocyte-derived dendritic cells in vitro	1
Unlocking the potential of lumateperone and novel anti-psychotics for schizophrenia	1
Investigating the function and targeting of MET protein as an oncogene kinase in pancreatic ductal adenocarcinoma: A microarray data integration	1
Reduced inflammation following human endometrial stromal/stem cell injection into male Wistar rats with cisplatin-induced acute kidney injury	1
A human acellular dermal matrix coated with zinc oxide nanoparticles accelerates tendon repair in patients with hand flexor tendon injuries in zone 5 of the hand	1
Sustained release microneedle patch for pronounced systemic delivery of doxazosin mesylate	1