OOIR: Observatory of International Research

Papers

(The TQCC of Annals of Laboratory Medicine is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Reducing Microbial Contamination in Hematopoietic Stem Cell Products and Quality Improvement Strategy: Retrospective Analysis of 1996-2021 Data	121
Challenges of Carbapenem-resistant Pseudomonas aeruginosa in Infection Control and Antibiotic Management	74
Expanding the Non-Invasive Diagnosis of Acute Rejection in Kidney Transplants Through Detection of Donor-Derived DNA in Urine: Proof-of-Concept Study	46
Validation of High-sensitivity Flow Cytometry for Reliable Immune Cell Analysis in Real-world Laboratory Settings	40
Optimization of a Protocol for Isolating Cell-free DNA From Cerebrospinal Fluid	40
Comparison of SARS-CoV-2 Antibody Responses and Seroconversion in COVID-19 Patients Using Twelve Commercial Immunoassays	39
Rapid Targeted Sequencing Using Dried Blood Spot Samples for Patients With Suspected Actionable Genetic Diseases	38
A New Strategy for Evaluating the Quality of Laboratory Results for Big Data Research: Using External Quality Assessment Survey Data (2010–2020)	38
A Novel Fibrinogen Assay Using Recombinant Batroxobin and Carboxymethyl Chitosan: Carboxymethyl Chitosan Stimulates the Enzymatic Activity of Recombinant Batroxobin	36
A Case of Bidirectional ABO- and RhD-Incompatible Liver Transplantation in a Mongolian Patient With Asian-Type DEL	35
Prediction of Mid-term Platelet Transfusion in Stable Trauma Patients Using Rotational Thromboelastometry	33
Performance Evaluation of the i-SmartCare 10 Analyzer and Method Comparison of Six Point-of-Care Blood Gas Analyzers	30
Update of Guidelines for Laboratory Diagnosis of COVID-19 in Korea	29
Clinical Practice Guideline for Blood-based Circulating Tumor DNA Assays	28
Complement Activation and Hemolysis in Non-human Primates Following Transfusion of Genetically Modified Pig Red Blood Cells	28
Effect of Variability on Interferon-Gamma Release Assay Performance: A Quantitative Analysis	27
Cost-effective BRCA Testing in Advanced Ovarian Cancer	26
Rapid Targeted Genomic Testing: A Powerful Tool for Diagnostic Evaluation of Critically Ill Neonates and Infants With Suspected Genetic Diseases	25
Granulocytic and Monocytic Myeloid-Derived Suppressor Cells are Functionally and Prognostically Different in Patients with Chronic Myeloid Leukemia	24
Current Status of Serum Insulin and C-Peptide Measurement in Clinical Laboratories: Experience from 94 Laboratories in China	24
RNA Sequencing for Elucidating an Intronic Variant of Uncertain Significance (SDHD c.314+3A>T) in Splicing Site Consensus Sequences	23
In-vitro Activities of Zoliflodacin and Solithromycin Against Neisseria gonorrhoeae Isolates from Korea	22
Association Between Low Anti-spike Antibody Levels After the Third Dose of SARS-CoV-2 Vaccination and Hospitalization due to Symptomatic Breakthrough Infection in Kidney Transplant Recipients	21
Clinical Differences in Patients Infected withFusobacteriumand Antimicrobial Susceptibility ofFusobacteriumIsolates Recovered at a Tertiary-Care Hospital in Korea	19
Development and Performance Validation of a Comprehensive Liquid Biopsy Genotyping Panel for Pan-cancer Analysis	18

Establishment of Reference Values for Non-HLA Antibodies in Patients With End-stage Renal Disease	17
Periodic Comparability Verification and Within-Laboratory Harmonization of Clinical Chemistry Laboratory Results at a Large Healthcare Center With Multiple Instruments	17
Reply to the Letter “The Stability of Blood Gas Parameters Depends on Leukocyte Count”	16
Sex-Specific U-Shaped Relationships Between High-Density Lipoprotein Cholesterol Levels and 10-year Major Adverse Cardiovascular Events: A Nationwide Cohort Study of 5.7 Million South Koreans	16
Investigation of the Neutralizing Antibody Response of Healthcare Workers at a Korean University Hospital Six Months After the Introduction of the COVID-19 Vaccine	16
Deciphering Epigenetic Backgrounds in a Korean Cohort with Beckwith–Wiedemann Syndrome	15
Collaborative Study to Establish National Reference Standards for Anti-HIV-1 Antibody	15
European Committee on Antimicrobial Susceptibility Testing-Recommended Rapid Antimicrobial Susceptibility Testing of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus	15
Proposed Model for Evaluating Real-world Laboratory Results for Big Data Research	15
The Issue With Osmotic Shock Hemolysate Preparation Procedure	15
Virulence-associated Genome Sequences of Pasteurella canis and Unique Toxin Gene Prevalence of P. canis and Pasteurella multocida Isolated from Humans and Companion Animals	15
The Use of Bone-Turnover Markers in Asia-Pacific Populations	14
Erratum: Serological Evidence of Coxiella burnetii and SARS-CoV-2 Co-Infection: A Case Report	14
Effect of Outlier Elimination on the 99th Percentile Upper Reference Limits of High-Sensitivity Cardiac Troponin I Assays Based on a Strictly Selected Healthy Reference Population	14
Clinical Sensitivity of the (1–3)-β-D-glucan Test for Predicting Candidemia	14
Effects of Various Concentrations of Pronase on Flow Cytometric Crossmatching Patients Treated With Rituximab and Donor HLA-Specific Antibodies	13
Analytical Interference of Exemestane With Androstenedione Immunoassays	13
Assessing the Relevance of Non-molecular Prognostic Systems for Myelodysplastic Syndrome in the Era of Next-Generation Sequencing	13
Endogenous Thrombin Potential Level Helps Predict High Blood Loss in Patients Undergoing Cardiac Surgery	13
Optimizing the Hospital Blood Bank Stock in Korea: A Comparative Analysis of the Uniform 5-Day Stock Index and a Novel Blood Stock Index	13
Investigation of Discrepant ABO Blood Grouping Results from an Autoanalyzer	12
The Stability of Blood Gas Parameters Depends on Leukocyte Counts	12
Cost-Effectiveness Analysis of Three Diagnostic Strategies for the Detection of EGFR Mutation in Advanced Non-Small Cell Lung Cancer	12
Predictive Performance of Neutrophil Gelatinase Associated Lipocalin, Liver Type Fatty Acid Binding Protein, and Cystatin C for Acute Kidney Injury and Mortality in Severely Ill Patients	12
Erratum : Comparing Genomic Characteristics of Streptococcus pyogenes Associated with Invasiveness over a 20-year Period in Korea	11
Fretibacterium Species to Fusobacterium periodonticum Ratio as a Potential Biomarker of Periodontitis Based on Salivary Microbiome Profiling	11
Evaluating the Commutability of Reference Materials for α-Fetoprotein: Accurate Value Assignment With Multiple Systems and Trueness Verification	11
Clinical Performance of the Standard Q COVID-19 Rapid Antigen Test and Simulation of its Real-World Application in Korea	11
Immunohistochemical Staining to Identify Concomitant Systemic Mastocytosis in Acute Myeloid Leukemia with RUNX1::RUNX1T1	10
Intuitive Modification of the Friedewald Formula for Calculation of LDL-Cholesterol	10
The First Case of Acute Myeloid Leukemia With t(10;11)(p13;q21);PICALM-MLLT10 Rearrangement Presenting With Extensive Skin Involvement	10
Association Between the Red Blood Cell Distribution Width and 30-Day Mortality in Intensive Care Patients Undergoing Cardiac Surgery: A Retrospective Observational Study Based on the Medical Informati	10
Clinical Evaluation of the Rapid STANDARD Q COVID-19 Ag Test for the Screening of Severe Acute Respiratory Syndrome Coronavirus 2	10
Clinical Application of Optical Genome Mapping for Molecular Diagnosis of Facioscapulohumeral Muscular Dystrophy	9
Risk Factors for Extended-Spectrum-β-Lactamase-Producing Escherichia coli in Community-Onset Bloodstream Infection: Impact on Long-Term Care Hospitals in Korea	9
Multiple Primary Cancers With Hematologic Malignancies and Germline Predisposition: A Case Series	9
Improvement of Anti-CD36 Antibody Detection via Monoclonal Antibody Immobilization of Platelet Antigens Assay by Using Selected Monoclonal Antibodies	9
Laboratory Preparation for Digital Medicine in Healthcare 4.0: An Investigation Into the Awareness and Applications of Big Data and Artificial Intelligence	9
Diagnostic Accuracy of Plasma Renin Concentration and Renin Activity in Predicting Mortality and Kidney Outcomes in Patients With Septic Shock and Hypoperfusion or Hypotension: A Multicenter, Prospect	9
High-resolution Chromosomal Microarray with Diagnostic Potential for Detecting Exon-level Copy Number Variations Using Targeted and Non-targeted Approaches	9
Optimization of Natural Killer Cell Expansion with K562-mbIL-18/-21 Feeder Cells and Assurance of Feeder Cell-free Products	9
Carrier Frequency and Incidence of MUTYH-Associated Polyposis Based on Database Analysis in East Asians and Koreans	8
Concurrent Pleural and Pericardial Involvement in a Patient With De Novo Pure Erythroid Leukemia	8
Prevalence of a Single-Nucleotide Variant of SARS-CoV-2 in Korea and Its Impact on the Diagnostic Sensitivity of the Xpert Xpress SARS-CoV-2 Assay	8
Comparison of Two Quinupristin–dalfopristin Susceptibility Testing Methods and Two Interpretive Criteria for Enterococcus faecium Bloodstream Isolates from Korean Hospitals	8
Platelet and Monocyte Microvesicles as Potential Biomarkers of COVID-19 Severity: A Cross-Sectional Analysis	8
Rapid Emergence of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 in Korea	8
Rare Non-Cryptic NUP98 Rearrangements Associated With Myeloid Neoplasms and Their Poor Prognostic Impact	8
The First Case of Pulmonary Mucormycosis Caused by Lichtheimia ornata	8
Platelet Satellitism: Just a Laboratory Curiosity? A Case Report of Platelet Satellitism with Multilineage Involvement	8

Choice of ABO Group for Blood Component Transfusion in ABO-Incompatible Solid Organ Transplantation: A Questionnaire Survey in Korea and Guideline Proposal	8
Laboratory Data Quality Evaluation in the Big Data Era	8
Performance Evaluation of the Roche Cobas 5800 HBV and HCV Tests: Comparison of the 200 and 500 μL Protocols	8
Performance Evaluation of the Aptima Assays in Comparison with the cobas 6800 Assays for the Detection of HIV-1, HBV, and HCV in Clinical Samples	8
Aberrant Splicing in PKD2 in a Family of Korean Patients With Autosomal Dominant Polycystic Kidney Disease	7
Natural Killer Cell Expansion and Cytotoxicity Differ Depending on the Culture Medium Used	7
New Issues With Neutrophil Gelatinase-associated Lipocalin in Acute Kidney Injury	7
Comprehensive Laboratory Data Analysis to Predict the Clinical Severity of Coronavirus Disease 2019 in 1,952 Patients in Daegu, Korea	7
Clinical Usefulness of a Cell-based Assay for Detecting Myelin Oligodendrocyte Glycoprotein Antibodies in Central Nervous System Inflammatory Disorders	7
Performance Evaluation of the DxC 700 AU Chemistry Analyzer in Hemoglobin A1c Measurement	7
Validation of Pathogenicity of Gene Variants in Fanconi Anemia Using Patient-derived Dermal Fibroblasts	7
An Unexpected Encounter During a Screening Colonoscopy in a Medical Tourist: A Diagnosis of Hymenolepis nana Infection	6
Comment on “Ionized Magnesium Correlates With Total Blood Magnesium in Pediatric Patients Following Kidney Transplant”	6
Disk Diffusion Susceptibility Testing for the Rapid Detection of Fluconazole Resistance in Candida Isolates	6
Neutralization Testing–based Immunogenicity Analysis of Recent Prevalent Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Sublineages	6
Clinical Utility of Methylation-Specific Multiplex Ligation-Dependent Probe Amplification for the Diagnosis of Prader–Willi Syndrome and Angelman Syndrome	6
Guidelines for the Laboratory Diagnosis of Monkeypox in Korea	6
Skeletal Muscle Mass Measurement via Bioelectrical Impedance Analysis as an Aid to Screen for Chronic Kidney Disease in Routine Health Checkups	6
Revolutionizing Laboratory Practices: Pioneering Trends in Total Laboratory Automation	6
A Machine Learning Approach to Reference Interval Estimation for Red Cell Parameters in a South and East Asian Population	6
Usefulness of Component-Resolved Diagnosis of Pollen-Food Allergy Syndrome	6
Comparison of Target- and IgG-Enrichment Strategies to Measure Adalimumab Concentrations in Human Plasma Using an Immunocapture-Liquid Chromatography-High-Resolution Mass Spectrometry Platform	6
The First Korean Case of Griscelli Syndrome Type 2 With Hemophagocytic Lymphohistiocytosis and Partial Albinism	6
SnackNTM: An Open-Source Software for Sanger Sequencing-based Identification of Nontuberculous Mycobacterial Species	6
Development of a Single-nucleotide Polymorphism Genotyping Assay for the Rapid Detection of Vancomycin-intermediate Resistance in Staphylococcus aureus Epidemic Lineage ST5	6
Manufacturing Cell and Gene Therapies: Challenges in Clinical Translation	5
Concurrent Nanopore Next-Generation Sequencing of Hepatitis B and Delta Virus Genomes Directly From Patient Plasma	5
Laboratory Aspects of Donor Screening for Fecal Microbiota Transplantation at a Korean Fecal Microbiota Bank	5
Reliability of the DI-60 Digital Image Analyzer for Detecting Platelet Clumping and Obtaining Accurate Platelet Counts	5
Integration of an MC-80 Digital Image Analyzer With an Automated BC-6800Plus Hematology Analyzer Enables Accurate Platelet Counting in Samples With EDTA-Induced Pseudothrombocytopenia	5
Accuracy of the New Creatinine-based Equations for Estimating Glomerular Filtration Rate in Koreans	5
RHDDNT* (RHD38*) Showing D-Positive Reactivity on Rhesus D Typing and Forming Anti-D Antibody	5
Suitability of EDTA-anticoagulated Blood for Natural Killer Cell Activity Testing Using Flow Cytometry	5
ABO Antibody Titer Testing Harmonization in Korea: A 5-Year Analysis of External Quality Control Data	5
Elevated Pleural Adenosine Deaminase Levels in IgG4-related Disease With Pleural Effusion: A Case Series	5
Hormone Immunoassay Interference: A 2021 Update	5
Impact of Low-level Donor-specific Antibody Determined With a Positive Luminex and Negative Flow Cytometric Crossmatch on Kidney Transplantation Outcomes	5
Diagnostic Performance of Eight Blood-based Biomarkers in a Well-characterized Korean Cohort of Preclinical Alzheimer’s Disease	5
Serotype Distribution and Antimicrobial Resistance of Streptococcus pneumoniae Causing Invasive Pneumococcal Disease in Korea Between 2017 and 2019 After Introduction of the 13-Valent Pneumococ	5
Educational Outcomes and Perception Changes in Medical Students After Visiting a Blood Donation Center	5
Evaluation of Cellular Responses to ChAdOx1-nCoV-19 and BNT162b2 Vaccinations	5
The First Case of Prosthesis-related Infection Caused by Quambalaria cyanescens in Korea	5
Predictors of Red Blood Cell Transfusion in Elderly COVID-19 Patients in Korea	5
Comparing Genomic Characteristics of Streptococcus pyogenes Associated with Invasiveness over a 20-year Period in Korea	5
Coexistence of Acute Promyelocytic Leukemia and Primary Plasma Cell Leukemia: Careful Consideration in Diagnosis	5
The First Korean Case of VEXAS Syndrome Caused by a UBA1 Somatic Variant	5
Increased Trend of Adenovirus Activity After the COVID-19 Pandemic in South Korea: Analysis of National Surveillance Data	5
Effect of Blood Collection Tubes on Vitamin D Immunoassay Results	5
Metformin Suppresses Both PD-L1 Expression in Cancer Cells and Cancer-Induced PD-1 Expression in Immune Cells to Promote Antitumor Immunity	5
Comparison of Measurable Residual Disease in Pediatric B-Lymphoblastic Leukemia Using Multiparametric Flow Cytometry and Next-Generation Sequencing	5
Interpretation of Folate Results in Hemolytic Plasma Samples: A Practical Approach	5
Genetic Counseling and Long-Term Surveillance Using a Multidisciplinary Approach in von Hippel–Lindau Disease	5
MYD88 L265P Variant Detection with Droplet Digital PCR in Waldenström Macroglobulinemia: Clinical Implications as a Tumor Burden and Prognostic Marker	5
Digital Morphology Analyzer Sysmex DI-60 vs. Manual Counting for White Blood Cell Differentials in Leukopenic Samples: A Comparative Assessment of Risk and Turnaround Time	5
Unreliable Automated Complete Blood Count Results: Causes, Recognition, and Resolution	5
Questionnaire Survey on Current Red Blood Cell Transport and Storage in Korea for Reducing Wastage	5
Concomitant Diagnosis of Primary Bone Marrow B-Cell Non-Hodgkin Lymphoma and Essential Thrombocythemia: A Case Report	5