Frontiers in Bioengineering and Biotechnology

Papers
(The median citation count of Frontiers in Bioengineering and Biotechnology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
An evaluation of the performance of medical helmets used in healthcare for the protection of vulnerable patients567
Editorial: Advances in biosulfidogenic processes386
Changes in volumetric bone mineral density after ACL reconstruction with single-bundle and double-bundle: a 1-year follow-up study using peripheral quantitative computed tomography368
Identification of a lumped-parameter model of the intervertebral joint from experimental data329
Seeing through cells: Rapid measurement of intracellular target proteins318
A convolutional neural network to characterize mouse hindlimb foot strikes during voluntary wheel running314
Incorporate delivery, warming and washing methods into efficient cryopreservation285
Recent developments on the application of molecular probes in multiple myeloma: Beyond [18F]FDG224
Agricultural biotechnology in the courts: judicial opinions and commentary223
Statistical genetics concepts in biomass-based materials engineering199
A non-hypothesis-driven practical laboratory activity on functional metagenomics: “fishing” protein-coding DNA sequences from microbiomes195
Advanced neuroprosthetic electrode design optimized by electromagnetic finite element simulation: innovations and applications176
Estimating within-stride metabolic cost from stride-average data using autoencoders and expander networks174
Cyclic RGD functionalized PLGA nanoparticles loaded with noncovalent complex of indocyanine green with urokinase for synergistic thrombolysis172
Viable cell sorting by fluidized bed centrifugation enables novel cultivation strategies162
Editorial: Multipotent stromal cells and microenvironment of the tissue healing159
Modulation of sirtuins during monolayer chondrocyte culture influences cartilage regeneration upon transfer to a 3D culture environment158
Editorial: Biofabricated materials for tissue engineering152
Short-term digital ocular massage may weaken corneal biomechanics150
Shoe choice may affect fencing lunge attack performance141
Biomechanical responses of peripheral nerves in human, pig and rat: a comparative study136
ELSAH (electronic smart patch system for wireless monitoring of molecular biomarkers for healthcare and wellbeing): definition of possible use cases133
Terahertz spectra of proteinuria and non-proteinuria131
In vivo prediction of intervertebral disc strains and segmental kinematics from clinical MRI during lumbar extension124
The efficacy of vancomycin-loaded biphasic calcium phosphate bone substitute in the promotion of new bone growth and the prevention of postoperative infection120
Calcium hydroxide coating for orthopedic implants: evaluation of osseointegrative and antibacterial properties in vivo118
Quantifying the effects of five rehabilitation training methods on the ability of elderly men to control bowel movements: a finite element analysis study116
Biphasic bone substitutes coated with PLGA incorporating therapeutic ions Sr2+ and Mg2+: cytotoxicity cascade and in vivo response of immune and bone regeneration106
Mesenchymal stem cell therapy for pulmonary hypertension: an update106
Nanomaterials reshape the pulmonary mechanical microenvironment: novel therapeutic strategies for respiratory diseases106
Magnetic drug-loaded microbubbles for treating lower limb venous thrombosis under controllable rotating magnetic field105
A novel “off-on” fluorescent probe for the detection of nickel ions and its clinical application103
Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission102
Improved catalytic performance and molecular insight for lipoxygenase from Enterovibrio norvegicus via directed evolution101
Multiple plant growth-promoting bacteria enhance rice growth in non-grain-converted lands100
Hydrogel co-loading SO2 prodrug and FeGA nanoparticles for enhancing chemodynamic therapy by photothermal-triggered SO2 gas therapy100
Biodegradable and injectable curcumin-loaded hydrogel for the prevention of postoperative intrauterine adhesion99
Zirconia/dental pulp stem cell composite scaffolds repair osteogenic defect via regulating macrophages99
A smart nanoplatform for enhanced photo-ferrotherapy of hepatocellular carcinoma98
Bioreactor as the root cause of the “manganese effect” during Aspergillus niger citric acid fermentations98
Prediction of stroke patients’ bedroom-stay duration: machine-learning approach using wearable sensor data96
Corrigendum: Determination of aortic characteristic impedance and total arterial compliance from regional pulse wave velocities using machine learning: an in silico study95
A noninvasive strategy for multi-disease diagnosis via multi-sensor platform: integrative analysis of five years of exhaled breath–based diagnostics for seven diseases91
Research on motion control of a novel stroke rehabilitation robot based on the dual parallel washout algorithm91
From detection to remediation: the potential of phosphomelanin in sustainable environmental solutions90
Quantifying the morphology of eyeballs with posterior staphyloma with Zernike polynomials89
Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions89
Smart nanoplatforms for early detection and immune modulation in lung cancer88
Editorial: Smart Stimuli-responsive Biomaterials for Programmed Drug Delivery86
Global research trends in extracellular vesicles based on stem cells from 1991 to 2021: A bibliometric and visualized study86
In vitro experiment and computational fluid dynamics simulation study on blood pump for total cavopulmonary connection circulation86
Variability of intervertebral joint stiffness between specimens and spine levels86
Altered activation patterns of the sensory-motor cortex in patients with knee osteoarthritis during knee isokinetic movement at different speeds85
A scalable corneal xenograft platform: simultaneous opportunities for tissue engineering and circular economic sustainability by repurposing slaughterhouse waste85
DDS-type near-infrared light absorber enables deeper lesion treatment in laser photothermal therapy while avoiding damage to surrounding organs84
Hybrid and adaptive control of functional electrical stimulation to correct hemiplegic gait for patients after stroke83
SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy82
Mussel-inspired HA@TA-CS/SA biomimetic 3D printed scaffolds with antibacterial activity for bone repair81
Decoding the exosomal secretome: stem cell-elicted microenvironmental reprogramming for anterior cruciate ligament regenerative medicine81
VP-net: an end-to-end deep learning network for elastic wave velocity prediction in human skin in vivo using optical coherence elastography80
Preparation, modification, and clinical application of porous tantalum scaffolds80
Viscoelastic damage evaluation of the axon79
The microbial production of kynurenic acid using Yarrowia lipolytica yeast growing on crude glycerol and soybean molasses79
Self-assembled microtissues loaded with osteogenic MSCs for in vivo bone regeneration78
Detection of calcitonin gene-related peptide based on increased antigen-driven interaction with antibody variable regions78
Current applications of nanomaterials in urinary system tumors78
320 mm InterTan nail optimizes biomechanics in AO/OTA 31A2.3 fractures: superior stress distribution, micromotion, and strain for enhanced healing78
Editorial: Advanced green polymers for medical purpose – trends and challenges in the circular economy77
Radiomics analysis using magnetic resonance imaging of bone marrow edema for diagnosing knee osteoarthritis76
Editorial: Metabolic engineering for bioresources and bioenergies production from microalgae75
Bio-inspired special wettability in oral antibacterial applications75
Functional data analysis of lower-limb joint kinematics during badminton lunges under fatigue75
Editorial: Bioengineering of biomimetic microenvironments for cardiac tissue engineering74
Editorial: Biomechanics, aging, exercise and other interventions74
Vibration stimulation enhances robustness in teleoperation robot system with EEG and eye-tracking hybrid control74
Cholesteric liquid crystal biosensor platform with image analysis for rapid detection of COVID-1974
Interaction between microorganisms and flavour products during cigar fermentation promoted by citrus Reticulata-“Chenpi” derived Enterobacter G5Z-2: based on multi-omics studies and microbial profiles73
Craniocaudal cyclic load improves risk assessment of lumbar pedicle screw loosening: finite element analysis based on computer tomography73
Intensification of 2′-Fucosyllactose biosynthesis pathway by using a novel fucosyltransferase from Bacillus cereus73
Strength of a cement-based dental material: Early age testing and first micromechanical modeling at mature age73
Influence of surface texturing and coatings on mechanical properties and integration with bone tissue: an in silico study73
Genome editing between wonder and rejection72
Design feature combinations effects of running shoe on plantar pressure during heel landing: A finite element analysis with Taguchi optimization approach72
Editorial: Nanotechnology-based devices and systems for enhanced sensitivity and efficiency in biomedical applications72
The outcome of digital technology in microvascular free flap reconstruction for ORNJ: a retrospective study71
An automated system for polymer wear debris analysis in total disc arthroplasty using convolution neural network70
FieldNA: a 3D printed vertical microfluidic device for portable nucleic acid isolation from olive oil samples70
Biomechanical study of different internal fixation devices for femoral neck fractures: finite element analysis based on different reduction qualities70
SiO2 nanosphere coated tough catheter with superhydrophobic surface for improving the antibacteria and hemocompatibility69
A method for generating dynamic compression shear coupled stress loading on living cells68
Mechanical stability of the interaction between a lower-limb rehabilitation exoskeleton and the user’s body during functional tasks68
Clinically feasible biomechanical assessment of lower limb strength and postural stability in adults aged 50–75 years with moderate knee osteoarthritis: implications for technology-enabled healthy agi67
BRET-based biosensors for SARS-CoV-2 oligonucleotide detection67
Cross-domain prediction approach of human lower limb voluntary movement intention for exoskeleton robot based on EEG signals67
Acoustic-propelled micro/nanomotors and nanoparticles for biomedical research, diagnosis, and therapeutic applications67
Microneedle-mediated drug delivery for cutaneous diseases67
Antibacterial and antioxidant phlorizin-loaded nanofiber film effectively promotes the healing of burn wounds66
Extrusion-based 3D printing of osteoinductive scaffolds with a spongiosa-inspired structure66
Development of a one-pot RPA-cas12a/13a assay for simultaneous detection of HPV16 and HPV1865
Hemostatic efficacy of a novel Ca/P/S-based bone graft material and its preliminary clinical evidence in sternum closure procedures64
Harnessing accurate mitochondrial DNA base editing mediated by DdCBEs in a predictable manner64
Research progress on biodegradable polymer-based drug delivery systems for the treatment of knee osteoarthritis63
Selective and mild oxidation of α-hydroxyl groups in lignin by 2-iodoxybenzoic acid63
Enabling 3D bioprinting of cell-laden pure collagen scaffolds via tannic acid supporting bath63
A small-diameter vascular graft immobilized peptides for capturing endothelial colony-forming cells63
Exploring the relationship between bearing extrusion and postoperative persistent pain in Oxford unicompartmental knee arthroplasty: A trajectory measurement study62
Role of microbial laccases in valorization of lignocellulosic biomass to bioethanol62
Dynamic segmental kinematics of the lumbar spine during diagnostic movements62
Application of MXene in the diagnosis and treatment of breast cancer: A critical overview62
The associations between lumbar proprioception and postural control during and after calf vibration in people with and without chronic low back pain61
Clinical evaluation and finite element analysis of bone cement-augmented anterolateral screw fixation versus percutaneous bilateral pedicle screw fixation co-applied with oblique lumbar interbody fusi61
Stability of internal fixation systems based on different subtypes of Schatzker II fracture of the tibial plateau: A finite element analysis60
Enabling the complete valorization of hybrid Pennisetum: Directly using alkaline black liquor for preparing UV-shielding biodegradable films60
Recent perspectives on the synergy of mesenchymal stem cells with micro/nano strategies in peripheral nerve regeneration-a review60
Stimuli-responsive hydrogels: smart state of-the-art platforms for cardiac tissue engineering60
Eldecalcitol effectively prevents alveolar bone loss by partially improving Th17/Treg cell balance in diabetes-associated periodontitis59
The effects of different carbon-fiber plate shapes in shoes on lower limb biomechanics following running-induced fatigue59
Pickering emulsion loaded with total flavonoids from Dracocephalum moldavica L. potentially promotes angiogenesis in the ischemic penumbra after cerebral ischemia reperfusion59
Substrate-inducible and antibiotic-free high-level 4-hydroxyvaleric acid production in engineered Escherichia coli58
Enabling and improving trans-nerolidol production by Corynebacterium glutamicum: combining metabolic engineering and trace elements medium refinement58
Transcriptomics of Lactobacillus paracasei: metabolism patterns and cellular responses under high-density culture conditions58
Evolution of pre- and post-operative balance characteristics in patients undergoing anterior cruciate ligament reconstruction: implications for rehabilitation58
Release of natural extracts from PVA and PVA-CMC hydrogel wound dressings: a power law swelling/delivery58
Personalized compression therapeutic textiles: digital design, development, and biomechanical evaluation58
Urine-derived stem cells: a sustainable resource for advancing personalized medicine and dental regeneration58
Mechanistic insights into the biological activity of S-Sulfocysteine in CHO cells using a multi-omics approach58
Wnt signaling directs human pluripotent stem cells into vascularized cardiac organoids with chamber-like structures58
Automated diagnosis and grading of lumbar intervertebral disc degeneration based on a modified YOLO framework57
Finite element analysis of optimized novel additively manufactured non-articulating prostheses for cervical total disc replacement57
Notch signaling pathway and heart development, congenital heart disease, and myocardial regeneration57
Editorial: Tissue engineering and regenerative medicine: advances, controversies, and future directions57
Synergistic antibacterial mechanism of silver-copper bimetallic nanoparticles57
Regulatory challenges and global trade implications of genome editing in agriculture57
Research trends in vascular chips from 2012 to 2022: a bibliometrix and visualized analysis57
Targeted drug delivery of engineered mesenchymal stem/stromal-cell-derived exosomes in cardiovascular disease: recent trends and future perspectives57
Therapeutic applications of synthetic gene/genetic circuits: a patent review56
Microbial composition play the leading role in volatile fatty acid production in the fermentation of different scale of corn stover with rumen fluid55
Biomechanical evaluation of a novel individualized zero-profile cage for anterior cervical discectomy and fusion: a finite element analysis55
Accurate classification of benign and malignant breast tumors in ultrasound imaging with an enhanced deep learning model55
Biomimetic hydrogel scaffolds for stimulating fibrotic responses: development of an in-vitro assay for implant material testing54
Electrospun aligned poly(ε-caprolactone) nanofiber yarns guiding 3D organization of tendon stem/progenitor cells in tenogenic differentiation and tendon repair54
Rapid molecular detection of Senecavirus A based on reverse transcription loop-mediated isothermal amplification (RT-LAMP) and CRISPR/Cas12a54
Engineering the glyoxylate cycle for chemical bioproduction54
An 8-step procedure-specific risk framework enables reproducible biosafety level assignment beyond agent-based classification53
Methane biohydroxylation into methanol by Methylosinus trichosporium OB3b: possible limitations and formate use during reaction53
The treatment efficacy of bone tissue engineering strategy for repairing segmental bone defects under diabetic condition53
Effects of non-invasive cervical spinal cord neuromodulation by trans-spinal electrical stimulation on cortico-muscular descending patterns in upper extremity of chronic stroke53
Investigations into the effects of scaffold microstructure on slow-release system with bioactive factors for bone repair53
Hydration monitoring and rehydration guidance system for athletes based on urine color’s L*a*b* parameters53
Rotation of the hammer and performance in hammer throwing53
Biomimetic superhydrophobic metal/nonmetal surface manufactured by etching methods: A mini review52
Enhanced photodynamic therapy through multienzyme-like MOF for cancer treatment52
Dehydrated silk fibroin matrices as versatile delivery systems for extracellular vesicles52
Optimization of guanosine-based hydrogels with boric acid derivatives for enhanced long-term stability and cell survival52
Application of bioreactor technology for cell culture-based viral vaccine production: Present status and future prospects52
Rethinking governance of synthetic cells51
Genetically engineered CD80–pMHC-harboring extracellular vesicles for antigen-specific CD4+ T-cell engagement51
Comparative analysis of porcine-uterine decellularization for bioactive-molecule preservation and DNA removal50
Cooperation between myofibril growth and costamere maturation in human cardiomyocytes50
Tumor-on-a-chip: Perfusable vascular incorporation brings new approach to tumor metastasis research and drug development50
Editorial: Advanced biomaterials for hard tissue repair and regeneration50
The impact of serum-free culture on HEK293 cells: From the establishment of suspension and adherent serum-free adaptation cultures to the investigation of growth and metabolic profiles50
Hemodynamic study: impact of anastomosis floor arterial stenosis on neointimal hyperplasia in hemodialysis arteriovenous fistulas50
Developing a standard definition for sequences of concern50
Biomechanical effects of orthodontic tooth movement on edentulous alveolar bone: a finite element analysis49
Quantitative evaluation of fracture healing progression in rat femurs with modal damping factor and conventional methods49
α-Hemihydrate calcium sulfate/n-hydroxyapatite combined with metformin promotes osteogenesis in vitro and in vivo49
The application of corneal biomechanical interocular asymmetry for the diagnosis of keratoconus and subclinical keratoconus49
Enhancing lycopene production in Bacillus subtilis by overcoming a critical enzymatic bottleneck49
Effective fractionation of lignocellulose components and lignin valorization by combination of deep eutectic solvent with ethanol49
CervSpineNet: a hybrid deep learning-based approach for the segmentation of cervical spinous processes49
An approach to the diagnosis of lumbar disc herniation using deep learning models49
Improved longevity and in vivo performance of neurotransmitter detection using 30 µm cone-shaped carbon fiber microelectrode49
Deciphering the microbial community structures and functions of wastewater treatment at high-altitude area49
Versatile electrical stimulator for cardiac tissue engineering—Investigation of charge-balanced monophasic and biphasic electrical stimulations48
Effects of a 12-week gait retraining program combined with foot core exercise on morphology, muscle strength, and kinematics of the arch: A randomized controlled trial48
11β hydroxysteroid dehydrogenase type 1 transgenic mesenchymal stem cells attenuate inflammation in models of sepsis48
Data-driven approach to integrating genomic and behavioral preclinical traumatic brain injury research48
Artificial intelligence to detect the femoral intertrochanteric fracture: The arrival of the intelligent-medicine era48
Strontium-doped apatitic bone cements with tunable antibacterial and antibiofilm ability48
Editorial: Bioactive materials for disease diagnosis and therapy48
Integrative modeling of hemodynamic changes and perfusion impairment in coronary microvascular disease48
In silico testing of a multimaterial scaffold for mandibular reconstruction48
Identification of the adhesive domain of AtaA from Acinetobacter sp. Tol 5 and its application in immobilizing Escherichia coli48
Editorial: Micro/nano optical devices for biosensing and cellular analysis48
Unlocking the therapeutic potential of Saussurea costus: purification and functional characterization of α-amylase inhibitors48
Editorial: Advances in theranostics: Novel nanotools for the treatment and diagnosis of tumors48
Excessive addition split peak formed by the non-templated nucleotide addition property of Taq DNA polymerase after PCR amplification47
Biosynthesis of aliphatic plastic monomers with amino residues in Yarrowia lipolytica47
Editorial: Advances in protein-based biomaterials for tissue engineering47
A proteomics analysis of neointima formation on decellularized vascular grafts reveals regenerative alterations in protein signature running head: Proteomics analysis of neointima formation47
Editorial: Bioengineered gene and cell therapy for treating cardiovascular diseases47
Editorial: Recent advances in application of synthetic biology for production of bioactive compounds, volume II47
A nanobody-based molecular toolkit for ubiquitin–proteasome system explores the main role of survivin subcellular localization47
Editorial: Enzyme design methodologies to enhance enzymatic yield47
Engineering bioactive mineralized tumor cells for tumor immunotherapy46
Using deep networks for knee range of motion monitoring in total knee arthroplasty rehabilitation46
Editorial: Advances in nanomedicine: revolutionizing healthcare with nanoscale innovations46
Accelerating wound healing by biomineralizing crystallization formed from ZIF-8/PLA nanofibers with enhanced revascularization and inflammation reduction46
A novel fluorescein sodium-based screening platform for the identification of sphingoid base-producing Wickerhamomyces ciferrii mutants46
Deep learning on brain metastasis for predicting EGFR genotype and EGFR-TKI therapy response in metastatic NSCLC: a multicenter study46
Design and application of artificial rare L-lysine codons in Corynebacterium glutamicum45
Biohybrids: Textile fibres provide scaffolds and highways for microbial translocation45
Analysis of digital vernier caliper versus digital thickness gauge consistency and user experience in measuring arterial wall thickness: implications for biomechanical assessment45
Animal models, treatment options, and biomaterials for female stress urinary incontinence45
Editorial: Design and synthesis of nanocarriers for enhancement of antigen immunogenicity45
Biomechanical analysis of spinal cord injury during scoliosis correction surgery45
Substitution of manure for mineral P fertilizers increases P availability by enhancing microbial potential for organic P mineralization in greenhouse soil45
Performance evaluation of biological safety cabinets: a real-world analysis45
Editorial: Additive manufacturing and biomaterials in regenerative dentistry45
Editorial: Mechanobiology at multiple scales45
Biomechanical effects of sex and bat size on head-directed blunt strikes45
Selective synthesis of rebaudioside M2 through structure-guided engineering of glycosyltransferase UGT94D145
Machine learning analysis with the comprehensive index of corneal tomographic and biomechanical parameters in detecting pediatric subclinical keratoconus44
A customizable cost-effective design for printed circuit board-based nanolayered gold screen-printed electrode: From fabrication to bioapplications44
Nucleic acid amplification strategies for volume-amplified magnetic nanoparticle detection assay44
A versatile, bioengineered skin reconstruction device designed for use in austere environments44
The role of nanotechnology-based approaches for clinical infectious diseases and public health44
Finite element and in vitro biomechanical analysis of a novel magnesium degradation-induced variable fixation plate44
A 3D-printed patient-specific modular implants for pelvic reconstruction of bone tumors involving the sacroiliac joint44
Effects of different reduction patterns on stress distribution in patients with intertrochanteric fractures with intramedullary nail fixation: a finite element analysis44
Degradation kinetics of medium chain length Polyhydroxyalkanoate degrading enzyme: a quartz crystal microbalance study44
Evaluation of polyetheretherketone composites modified by calcium silicate and carbon nanotubes for bone regeneration: mechanical properties, biomineralization and induction of osteoblasts44
A wearable functional electrical stimulation device with a movable electrode for motor point tracking43
Evaluation of the hemostatic efficacy and safety of an absorbable hemostatic powder based on a porcine intracranial hemorrhage model43
Procedure to categorize wheelchair cushion performance using compliant buttock models43
Microbial (E)-4-hydroxy-3-methylbut-2-enyl pyrophosphate reductase (IspH) and its biotechnological potential: A mini review43
Niobium carbide–mediated photothermal therapy for infected wound treatment43
Corrigendum: Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions43
Effect of myopia and astigmatism deepening on the corneal biomechanical parameter stress-strain index in individuals of Chinese ethnicity43
Robust slice-level stroke classification in non-contrast head CT via structural consistency regularization and counterfactual suppression42
Editorial: Application of innovative techniques in genetic and cellular therapies42
Opportunities and challenges of natural killer cell-derived extracellular vesicles42
Multi-mode adaptive control strategy for a lower limb rehabilitation robot42
Rebuilding vascular access: from the viewpoint of mechanics and materials42
Computational study of the balloon dilation steps on transcatheter aortic valve replacement42
Focused ultrasound in modern medicine: bioengineering interfaces, molecular effects, and clinical breakthroughs42
Evaluation of four machine learning methods in predicting orthodontic extraction decision from clinical examination data and analysis of feature contribution42
Development of a fibroblast activation protein-targeted PET/NIR dual-modality probe and its application in head and neck cancer42
DNA microarrays to identify etiological agents, as sensors of environmental wellbeing42
Cerium oxide nanoparticles protect against chondrocytes and cartilage explants from oxidative stress via Nrf2/HO-1 pathway in temporomandibular joint osteoarthritis42
Definition, measurement, and function of pore structure dimensions of bioengineered porous bone tissue materials based on additive manufacturing: A review42
Radiofrequency ablation with sine and square electrical waveforms to enhance ablation range41
Microbially derived surfactants: an ecofriendly, innovative, and effective approach for managing environmental contaminants41
Biomechanical comparison of intramedullary nail and plate osteosynthesis for extra-articular proximal tibial fractures with segmental bone defect41
Editorial: Non-viral vectors for gene therapy/nucleic acid delivery41
Analysis of the geometrical influence of ring-opening samples on arterial circumferential residual stress reconstruction41
Release kinetics of growth factors loaded into β-TCP ceramics in an in vitro model41
Improved understanding of biorisk for research involving microbial modification using annotated sequences of concern41
Accuracy of tomographic and biomechanical parameters in detecting unilateral post-LASIK keratoectasia and fellow eyes40
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