OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Molecular Biosciences is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Implementation of a combined bioinformatics and experimental approach to address lncRNA mechanism of action: The example of NRIR	203
Machine learning-enhanced insights into sphingolipid-based prognostication: revealing the immunological landscape and predictive proficiency for immunomotherapy and chemotherapy responses in pancreati	197
Editorial: In celebration of women in science: RNA networks and biology	180
Editorial: Analytical devices based on immobilized macromolecules for structural and activity/affinity studies in drug discovery	168
Editorial: Interactions of nanoparticles with and within living organisms—What can we learn to improve efficacy of nanomedicine?	142
Melasolv™: a potential preventive and depigmenting agent for the senescence of melanocytes	134
Biochemical and Structural Characterization of Thermostable GH159 Glycoside Hydrolases Exhibiting α-L-Arabinofuranosidase Activity	118
Preparation of RNAs with non-canonical 5′ ends using novel di- and trinucleotide reagents for co-transcriptional capping	115
The endothelial layer formation in the presence of AuNPs/CdSe/TaNPs-loaded PLCL/PVP-based electrospun nanofibers	110
Editorial: Novel approaches aiming to overcome current nanomedicine limitations	102
Editorial: Ironome: a still untapped frontier	98
Application of PCR-based approaches for evaluation of cell-free DNA fragmentation in colorectal cancer	96
Detection of mutations: from Ames test to duplex sequencing	95
Identification of biomarkers and immune microenvironment associated with pterygium through bioinformatics and machine learning	94
Comparative analysis of tissue-specific anticancer peptide prediction models: ACP-Boost framework	93
Editorial: In honor of Dr. Bruce Ames: innovations in mutagenesis and DNA repair	90
Moving HER2-low breast cancer predictive and prognostic data from clinical trials into the real world	89
A novel pyroptosis-regulated gene signature for predicting prognosis and immunotherapy response in hepatocellular carcinoma	86
Mechanosensory encoding dysfunction emerges from cancer-chemotherapy interaction	82
Cardiolipin occupancy profiles of YidC paralogs reveal the significance of respective TM2 helix residues in determining paralog-specific phenotypes	78
Corrigendum: Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project	78
Untargeted Metabolomics Studies of H9c2 Cardiac Cells Submitted to Oxidative Stress, β-Adrenergic Stimulation and Doxorubicin Treatment: Investigation of Cardiac Biomarkers	72
Opto-APC: Engineering of cells that display phytochrome B on their surface for optogenetic studies of cell-cell interactions	71
Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis	69
Zinc phthalocyanine loaded- antibody functionalized nanoparticles enhance photodynamic therapy in monolayer (2-D) and multicellular tumour spheroid (3-D) cell cultures	68

Modeling of pneumococcal serogroup 10 capsular polysaccharide molecular conformations provides insight into epitopes and observed cross-reactivity	68
Keeping up with the condensates: The retention, gain, and loss of nuclear membrane-less organelles	68
Hotspots of single-strand DNA “breakome” are enriched at transcriptional start sites of genes	67
Untargeted metabolomics reveals immune-metabolic signatures in established cases of rheumatoid arthritis	66
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats	66
Type-2 diabetes epigenetic biomarkers: present status and future directions for global and Indigenous health	64
ER exit in physiology and disease	62
A systematic review reveals conflicting evidence for the prevalence of antibodies against the sialic acid ‘xenoautoantigen’ Neu5Gc in humans and the need for a standardised approach to quantification	62
Shared pathobiology identifies AMPK as a therapeutic target for obesity and autosomal dominant polycystic kidney disease	62
Enhanced enrichment of extracellular vesicles for laboratory and clinical research from drop-sized blood samples	61
Interaction of gut microbiota with the tumor microenvironment: A new strategy for antitumor treatment and traditional Chinese medicine in colorectal cancer	60
Production and characterization of monoclonal antibodies for the detection of the hepatitis C core antigen	59
Sex-dependent alterations of salivary microbiome in Parkinson’s disease: associations with motor and non-motor clinical phenotypes	58
RNA sequencing-based profiling of differentially expressed microRNAs in endothelial cells from offspring of hypertensive pregnancies: a preliminary study	57
Creatinine, leucine, and tetrahydrocorticosterone emerge as potential biomarkers for the diagnosis of sarcopenic osteoarthritis in middle-aged and elderly individuals: a cross-sectional exploratory st	57
ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis	57
Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis	57
Deepening insights into cholinergic agents for intraocular pressure reduction: systems genetics, molecular modeling, and in vivo perspectives	57
Metabolome combined with gut microbiome revealed the lipid-lowering mechanism of Xuezhiping capsule on hyperlipidemic hamster induced by high fat diet	56
Revealing the pharmacological effect and mechanism of darutoside on gouty arthritis by liquid chromatography/mass spectrometry and metabolomics	55
The application of exosomes in the treatment of triple-negative breast cancer	54
The chemistry of gut microbiome-derived lipopolysaccharides impacts on the occurrence of food allergy in the pediatric age	54
Study on the metabolic effects of hexavalent chromium [Cr (VI)] on rat astrocytes using un-targeted metabolomics	54
Serum bile acid metabolic profiles in polycystic ovary syndrome: insights from targeted metabolomics and correlation with embryonic parameters	53
Current research on fungi in chronic wounds	53
Serum Untargeted Metabolomics Reveal Potential Biomarkers of Progression of Diabetic Retinopathy in Asians	53
A potential allosteric inhibitor of SARS-CoV-2 main protease (Mpro) identified through metastable state analysis	52
FABP4 in obesity-associated carcinogenesis: Novel insights into mechanisms and therapeutic implications	52
Integrating network analysis with differential expression to uncover therapeutic and prognostic biomarkers in esophageal squamous cell carcinoma	52
Identification of novel gene signatures and immune cell infiltration in intervertebral disc degeneration using bioinformatics analysis	52