OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Molecular Biosciences is 54. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Editorial: Ironome: a still untapped frontier	377
Large-Scale Gastric Cancer Susceptibility Gene Identification Based on Gradient Boosting Decision Tree	269
Preparation of RNAs with non-canonical 5′ ends using novel di- and trinucleotide reagents for co-transcriptional capping	246
A Simple and Sensitive UPLC–UV Method for Simultaneous Determination of Isoniazid, Pyrazinamide, and Rifampicin in Human Plasma and Its Application in Therapeutic Drug Monitoring	190
Structural Basis for Allostery in PLP-dependent Enzymes	150
p53–GSDME Elevation: A Path for CDK7 Inhibition to Suppress Breast Cancer Cell Survival	125
Editorial: Analytical devices based on immobilized macromolecules for structural and activity/affinity studies in drug discovery	119
Deepening insights into cholinergic agents for intraocular pressure reduction: systems genetics, molecular modeling, and in vivo perspectives	115
ER exit in physiology and disease	105
Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells—implications for blood-brain barrier	104
Serum Untargeted Metabolomics Reveal Potential Biomarkers of Progression of Diabetic Retinopathy in Asians	102
Modeling of pneumococcal serogroup 10 capsular polysaccharide molecular conformations provides insight into epitopes and observed cross-reactivity	102
Investigating potential targets of Wulingsan in diabetic nephropathy through network pharmacology and experimental validation	98
N-3 Polyunsaturated Fatty Acid Dehydrogenase Fat-1 Regulates Mitochondrial Energy Metabolism by Altering DNA Methylation in Isolated Cells of Transgenic Cattle	97
Integrative Analyses and Verification of the Expression and Prognostic Significance for RCN1 in Glioblastoma Multiforme	97
Transcriptome Sequencing Reveals Key Genes in Three Early Phases of Osteogenic, Adipogenic, and Chondrogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Rats	92
Corrigendum: RUNX1 Upregulates CENPE to Promote Leukemic Cell Proliferation	91
miR-3587 Inhibitor Attenuates Ferroptosis Following Renal Ischemia-Reperfusion Through HO-1	89
A Conserved Mitochondrial Chaperone-Protease Complex Involved in Protein Homeostasis	88
Autosomal dominant and autosomal recessive polycystic kidney disease: hypertension and secondary cardiovascular effect in children	87
Understanding the impact of in vitro transcription byproducts and contaminants	86
Interaction of gut microbiota with the tumor microenvironment: A new strategy for antitumor treatment and traditional Chinese medicine in colorectal cancer	85
Keeping up with the condensates: The retention, gain, and loss of nuclear membrane-less organelles	83
Moving HER2-low breast cancer predictive and prognostic data from clinical trials into the real world	80
Metabolome combined with gut microbiome revealed the lipid-lowering mechanism of Xuezhiping capsule on hyperlipidemic hamster induced by high fat diet	79

Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis	79
Identification of novel gene signatures and immune cell infiltration in intervertebral disc degeneration using bioinformatics analysis	79
Editorial: Novel approaches aiming to overcome current nanomedicine limitations	78
The Many Faces of G Protein-Coupled Receptor 143, an Atypical Intracellular Receptor	78
ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation	77
Study on the metabolic effects of hexavalent chromium [Cr (VI)] on rat astrocytes using un-targeted metabolomics	73
Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis	71
Drugging Fuzzy Complexes in Transcription	71
Hotspots of single-strand DNA “breakome” are enriched at transcriptional start sites of genes	69
Identification of biomarkers and immune microenvironment associated with pterygium through bioinformatics and machine learning	67
Editorial: In celebration of women in science: RNA networks and biology	66
Crystalline Sponge Method by Three-Dimensional Electron Diffraction	65
The application of exosomes in the treatment of triple-negative breast cancer	64
Corrigendum: Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project	62
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats	61
Regulatory Non-coding RNAs for Death Associated Protein Kinase Family	61
Revealing the pharmacological effect and mechanism of darutoside on gouty arthritis by liquid chromatography/mass spectrometry and metabolomics	61
Application of PCR-based approaches for evaluation of cell-free DNA fragmentation in colorectal cancer	61
ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis	60
A novel pyroptosis-regulated gene signature for predicting prognosis and immunotherapy response in hepatocellular carcinoma	59
Development of Molecular Mechanisms and Their Application on Oncolytic Newcastle Disease Virus in Cancer Therapy	59
Editorial: The Dual-Use Dilemma for Biomimicry	58
Melasolv™: a potential preventive and depigmenting agent for the senescence of melanocytes	57
Editorial: Interactions of nanoparticles with and within living organisms—What can we learn to improve efficacy of nanomedicine?	57
Production and characterization of monoclonal antibodies for the detection of the hepatitis C core antigen	57
Position Specific Alternative Splicing and Gene Expression Profiles Along the Tonotopic Axis of Chick Cochlea	56
Ranolazine Inhibits Pyroptosis via Regulation of miR-135b in the Treatment of Diabetic Cardiac Fibrosis	55
Role of a Modified Urothelium Immune Prognostic Index in Patients With Metastatic Urothelial Carcinoma Treated With Anti–PD-1/PD-L1–Based Therapy	54
Cardiolipin occupancy profiles of YidC paralogs reveal the significance of respective TM2 helix residues in determining paralog-specific phenotypes	54