OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Molecular Biosciences is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Implementation of a combined bioinformatics and experimental approach to address lncRNA mechanism of action: The example of NRIR	196
Machine learning-enhanced insights into sphingolipid-based prognostication: revealing the immunological landscape and predictive proficiency for immunomotherapy and chemotherapy responses in pancreati	189
Editorial: In celebration of women in science: RNA networks and biology	173
Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells—implications for blood-brain barrier	162
Editorial: Analytical devices based on immobilized macromolecules for structural and activity/affinity studies in drug discovery	138
Integrating network analysis with differential expression to uncover therapeutic and prognostic biomarkers in esophageal squamous cell carcinoma	123
ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation	117
Editorial: The Dual-Use Dilemma for Biomimicry	112
Editorial: Interactions of nanoparticles with and within living organisms—What can we learn to improve efficacy of nanomedicine?	110
Melasolv™: a potential preventive and depigmenting agent for the senescence of melanocytes	101
Biochemical and Structural Characterization of Thermostable GH159 Glycoside Hydrolases Exhibiting α-L-Arabinofuranosidase Activity	100
Preparation of RNAs with non-canonical 5′ ends using novel di- and trinucleotide reagents for co-transcriptional capping	96
The endothelial layer formation in the presence of AuNPs/CdSe/TaNPs-loaded PLCL/PVP-based electrospun nanofibers	92
Serum Untargeted Metabolomics Reveal Potential Biomarkers of Progression of Diabetic Retinopathy in Asians	91
Editorial: Novel approaches aiming to overcome current nanomedicine limitations	90
Identification of diagnostic hub genes related to energy metabolism in idiopathic pulmonary fibrosis	86
A role of salt bridges in mediating drug potency: A lesson from the N-myristoyltransferase inhibitors	85
Editorial: Ironome: a still untapped frontier	85
Application of PCR-based approaches for evaluation of cell-free DNA fragmentation in colorectal cancer	82
Detection of mutations: from Ames test to duplex sequencing	80
Identification of biomarkers and immune microenvironment associated with pterygium through bioinformatics and machine learning	79
Comparative analysis of tissue-specific anticancer peptide prediction models: ACP-Boost framework	77
Autosomal dominant and autosomal recessive polycystic kidney disease: hypertension and secondary cardiovascular effect in children	74
From in vitro to in silico: a pipeline for generating virtual tissue simulations from real image data	70
A novel pyroptosis-regulated gene signature for predicting prognosis and immunotherapy response in hepatocellular carcinoma	67

Moving HER2-low breast cancer predictive and prognostic data from clinical trials into the real world	67
Editorial: In honor of Dr. Bruce Ames: innovations in mutagenesis and DNA repair	67
Identification of novel gene signatures and immune cell infiltration in intervertebral disc degeneration using bioinformatics analysis	66
Curcumin-mediated transcriptional regulation of human N-acetylgalactosamine-α2,6-sialyltransferase which synthesizes sialyl-Tn antigen in HCT116 human colon cancer cells	66
Mechanosensory encoding dysfunction emerges from cancer-chemotherapy interaction	64
Cardiolipin occupancy profiles of YidC paralogs reveal the significance of respective TM2 helix residues in determining paralog-specific phenotypes	63
Corrigendum: Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project	62
Opto-APC: Engineering of cells that display phytochrome B on their surface for optogenetic studies of cell-cell interactions	61
Study on the metabolic effects of hexavalent chromium [Cr (VI)] on rat astrocytes using un-targeted metabolomics	61
Untargeted Metabolomics Studies of H9c2 Cardiac Cells Submitted to Oxidative Stress, β-Adrenergic Stimulation and Doxorubicin Treatment: Investigation of Cardiac Biomarkers	61
Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis	60
Keeping up with the condensates: The retention, gain, and loss of nuclear membrane-less organelles	59
Investigating potential targets of Wulingsan in diabetic nephropathy through network pharmacology and experimental validation	58
Development of Molecular Mechanisms and Their Application on Oncolytic Newcastle Disease Virus in Cancer Therapy	56
Modeling of pneumococcal serogroup 10 capsular polysaccharide molecular conformations provides insight into epitopes and observed cross-reactivity	56
Zinc phthalocyanine loaded- antibody functionalized nanoparticles enhance photodynamic therapy in monolayer (2-D) and multicellular tumour spheroid (3-D) cell cultures	56
Bioactive chemical composition and pharmacological insights into Salvia species	55
Enhanced enrichment of extracellular vesicles for laboratory and clinical research from drop-sized blood samples	55
Structural Details of BH3 Motifs and BH3-Mediated Interactions: an Updated Perspective	54
Production and characterization of monoclonal antibodies for the detection of the hepatitis C core antigen	54
Interaction of gut microbiota with the tumor microenvironment: A new strategy for antitumor treatment and traditional Chinese medicine in colorectal cancer	54
ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis	53
Sex-dependent alterations of salivary microbiome in Parkinson’s disease: associations with motor and non-motor clinical phenotypes	53
Creatinine, leucine, and tetrahydrocorticosterone emerge as potential biomarkers for the diagnosis of sarcopenic osteoarthritis in middle-aged and elderly individuals: a cross-sectional exploratory st	52
Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis	52
Deepening insights into cholinergic agents for intraocular pressure reduction: systems genetics, molecular modeling, and in vivo perspectives	52
The chemistry of gut microbiome-derived lipopolysaccharides impacts on the occurrence of food allergy in the pediatric age	52
RNA sequencing-based profiling of differentially expressed microRNAs in endothelial cells from offspring of hypertensive pregnancies: a preliminary study	52