Frontiers in Molecular Biosciences

Article	Citations
Editorial: Ironome: a still untapped frontier	377
Large-Scale Gastric Cancer Susceptibility Gene Identification Based on Gradient Boosting Decision Tree	269
Preparation of RNAs with non-canonical 5′ ends using novel di- and trinucleotide reagents for co-transcriptional capping	246
A Simple and Sensitive UPLC–UV Method for Simultaneous Determination of Isoniazid, Pyrazinamide, and Rifampicin in Human Plasma and Its Application in Therapeutic Drug Monitoring	190
Structural Basis for Allostery in PLP-dependent Enzymes	150
p53–GSDME Elevation: A Path for CDK7 Inhibition to Suppress Breast Cancer Cell Survival	125
Editorial: Analytical devices based on immobilized macromolecules for structural and activity/affinity studies in drug discovery	119
Deepening insights into cholinergic agents for intraocular pressure reduction: systems genetics, molecular modeling, and in vivo perspectives	115
ER exit in physiology and disease	105
Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells—implications for blood-brain barrier	104
Modeling of pneumococcal serogroup 10 capsular polysaccharide molecular conformations provides insight into epitopes and observed cross-reactivity	102
Serum Untargeted Metabolomics Reveal Potential Biomarkers of Progression of Diabetic Retinopathy in Asians	102
Investigating potential targets of Wulingsan in diabetic nephropathy through network pharmacology and experimental validation	98
Integrative Analyses and Verification of the Expression and Prognostic Significance for RCN1 in Glioblastoma Multiforme	97
N-3 Polyunsaturated Fatty Acid Dehydrogenase Fat-1 Regulates Mitochondrial Energy Metabolism by Altering DNA Methylation in Isolated Cells of Transgenic Cattle	97
Transcriptome Sequencing Reveals Key Genes in Three Early Phases of Osteogenic, Adipogenic, and Chondrogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Rats	92
Corrigendum: RUNX1 Upregulates CENPE to Promote Leukemic Cell Proliferation	91
miR-3587 Inhibitor Attenuates Ferroptosis Following Renal Ischemia-Reperfusion Through HO-1	89
A Conserved Mitochondrial Chaperone-Protease Complex Involved in Protein Homeostasis	88
Autosomal dominant and autosomal recessive polycystic kidney disease: hypertension and secondary cardiovascular effect in children	87
Understanding the impact of in vitro transcription byproducts and contaminants	86
Interaction of gut microbiota with the tumor microenvironment: A new strategy for antitumor treatment and traditional Chinese medicine in colorectal cancer	85
Keeping up with the condensates: The retention, gain, and loss of nuclear membrane-less organelles	83
Moving HER2-low breast cancer predictive and prognostic data from clinical trials into the real world	80
Identification of novel gene signatures and immune cell infiltration in intervertebral disc degeneration using bioinformatics analysis	79

Metabolome combined with gut microbiome revealed the lipid-lowering mechanism of Xuezhiping capsule on hyperlipidemic hamster induced by high fat diet	79
Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis	79
The Many Faces of G Protein-Coupled Receptor 143, an Atypical Intracellular Receptor	78
Editorial: Novel approaches aiming to overcome current nanomedicine limitations	78
ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation	77
Study on the metabolic effects of hexavalent chromium [Cr (VI)] on rat astrocytes using un-targeted metabolomics	73
Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis	71
Drugging Fuzzy Complexes in Transcription	71
Hotspots of single-strand DNA “breakome” are enriched at transcriptional start sites of genes	69
Identification of biomarkers and immune microenvironment associated with pterygium through bioinformatics and machine learning	67
Editorial: In celebration of women in science: RNA networks and biology	66
Crystalline Sponge Method by Three-Dimensional Electron Diffraction	65
The application of exosomes in the treatment of triple-negative breast cancer	64
Corrigendum: Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project	62
Regulatory Non-coding RNAs for Death Associated Protein Kinase Family	61
Revealing the pharmacological effect and mechanism of darutoside on gouty arthritis by liquid chromatography/mass spectrometry and metabolomics	61
Application of PCR-based approaches for evaluation of cell-free DNA fragmentation in colorectal cancer	61
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats	61
ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis	60
A novel pyroptosis-regulated gene signature for predicting prognosis and immunotherapy response in hepatocellular carcinoma	59
Development of Molecular Mechanisms and Their Application on Oncolytic Newcastle Disease Virus in Cancer Therapy	59
Editorial: The Dual-Use Dilemma for Biomimicry	58
Editorial: Interactions of nanoparticles with and within living organisms—What can we learn to improve efficacy of nanomedicine?	57
Production and characterization of monoclonal antibodies for the detection of the hepatitis C core antigen	57
Melasolv™: a potential preventive and depigmenting agent for the senescence of melanocytes	57
Position Specific Alternative Splicing and Gene Expression Profiles Along the Tonotopic Axis of Chick Cochlea	56
Ranolazine Inhibits Pyroptosis via Regulation of miR-135b in the Treatment of Diabetic Cardiac Fibrosis	55
Cardiolipin occupancy profiles of YidC paralogs reveal the significance of respective TM2 helix residues in determining paralog-specific phenotypes	54
Role of a Modified Urothelium Immune Prognostic Index in Patients With Metastatic Urothelial Carcinoma Treated With Anti–PD-1/PD-L1–Based Therapy	54
Current research on fungi in chronic wounds	53
Shared pathobiology identifies AMPK as a therapeutic target for obesity and autosomal dominant polycystic kidney disease	53
Two-Metal-Ion Catalysis: Inhibition of DNA Polymerase Activity by a Third Divalent Metal Ion	51
The chemistry of gut microbiome-derived lipopolysaccharides impacts on the occurrence of food allergy in the pediatric age	51
Characterization of METTL7B to Evaluate TME and Predict Prognosis by Integrative Analysis of Multi-Omics Data in Glioma	51
Zinc phthalocyanine loaded- antibody functionalized nanoparticles enhance photodynamic therapy in monolayer (2-D) and multicellular tumour spheroid (3-D) cell cultures	51
Pan-Cancer Analysis and Validation Reveals that D-Dimer-Related Genes are Prognostic and Downregulate CD8+ T Cells via TGF-Beta Signaling in Gastric Cancer	50
Identification of Crucial Hub Genes and Differential T Cell Infiltration in Idiopathic Pulmonary Arterial Hypertension Using Bioinformatics Strategies	50
Bioinformatics-Guided Analysis Uncovers AOX1 as an Osteogenic Differentiation-Relevant Gene of Human Mesenchymal Stem Cells	50
Technical Validation and Clinical Utility of an NGS Targeted Panel to Improve Molecular Characterization of Pediatric Acute Leukemia	50
Implementation of a combined bioinformatics and experimental approach to address lncRNA mechanism of action: The example of NRIR	49
Enhanced enrichment of extracellular vesicles for laboratory and clinical research from drop-sized blood samples	49
Opto-APC: Engineering of cells that display phytochrome B on their surface for optogenetic studies of cell-cell interactions	48
Development and Application of RAA Nucleic Acid Test Strip Assay and Double RAA Gel Electrophoresis Detection Methods for ASFV and CSFV	47
Missense Mutations Modify the Conformational Ensemble of the α-Synuclein Monomer Which Exhibits a Two-Phase Characteristic	47
Structural Details of BH3 Motifs and BH3-Mediated Interactions: an Updated Perspective	47
From in vitro to in silico: a pipeline for generating virtual tissue simulations from real image data	46
A potential allosteric inhibitor of SARS-CoV-2 main protease (Mpro) identified through metastable state analysis	46
Machine learning-enhanced insights into sphingolipid-based prognostication: revealing the immunological landscape and predictive proficiency for immunomotherapy and chemotherapy responses in pancreati	45
Integrating network analysis with differential expression to uncover therapeutic and prognostic biomarkers in esophageal squamous cell carcinoma	45
Biochemical and Structural Characterization of Thermostable GH159 Glycoside Hydrolases Exhibiting α-L-Arabinofuranosidase Activity	45

Computational Insights Into the Effects of the R190K and N121Q Mutations on the SARS-CoV-2 Spike Complex With Biliverdin	45
Identification of diagnostic hub genes related to energy metabolism in idiopathic pulmonary fibrosis	45
A systematic review reveals conflicting evidence for the prevalence of antibodies against the sialic acid ‘xenoautoantigen’ Neu5Gc in humans and the need for a standardised approach to quantification	45
Untargeted Metabolomics Studies of H9c2 Cardiac Cells Submitted to Oxidative Stress, β-Adrenergic Stimulation and Doxorubicin Treatment: Investigation of Cardiac Biomarkers	43
Potential Molecular Targets of Tenofovir Disoproxil Fumarate for Alleviating Chronic Liver Diseases via a Non-Antiviral Effect in a Normal Mouse Model	43
Type-2 diabetes epigenetic biomarkers: present status and future directions for global and Indigenous health	43
High CTC-TRPC5 Expression Significantly Associated With Poor Prognosis in Radical Resected Colorectal Cancer Patients	43
Mechanosensory encoding dysfunction emerges from cancer-chemotherapy interaction	43
Curcumin-mediated transcriptional regulation of human N-acetylgalactosamine-α2,6-sialyltransferase which synthesizes sialyl-Tn antigen in HCT116 human colon cancer cells	42
The Role of the Thioredoxin Detoxification System in Cancer Progression and Resistance	42
Carbon Dioxide and the Carbamate Post-Translational Modification	42
A role of salt bridges in mediating drug potency: A lesson from the N-myristoyltransferase inhibitors	41
FABP4 in obesity-associated carcinogenesis: Novel insights into mechanisms and therapeutic implications	41
Personalized nutrition, microbiota, and metabolism: A triad for eudaimonia	40
Tumor-Derived Extracellular Vesicles Regulate Cancer Progression in the Tumor Microenvironment	40
Gene expression profiling of human umbilical vein endothelial cells overexpressing CELF2 as diagnostic targets in diabetes-induced erectile dysfunction	40
SMARCC1 Enters the Nucleus via KPNA2 and Plays an Oncogenic Role in Bladder Cancer	40
The Multi-Functional Roles of CCR7 in Human Immunology and as a Promising Therapeutic Target for Cancer Therapeutics	39
Redox Switches in Noise-Induced Cardiovascular and Neuronal Dysregulation	39
Lapatinib-induced enhancement of mitochondrial respiration in HER2-positive SK-BR-3 cells: mechanism revealed by analysis of proteomic but not transcriptomic data	39
Diagnostic Potential of Plasma Extracellular Vesicle miR-483-3p and Let-7d-3p for Sepsis	39
Optimal Detection of Fusion Pore Dynamics Using Polarized Total Internal Reflection Fluorescence Microscopy	39
Molecular Big Data in Sports Sciences: State-of-Art and Future Prospects of OMICS-Based Sports Sciences	38
Novel Brain-Stiffness-Mimicking Matrix Gel Enables Comprehensive Invasion Analysis of 3D Cultured GBM Cells	38
Development of a top-down MS assay for specific identification of human periostin isoforms	38
The Role of Long Non-Coding RNAs in Epithelial-Mesenchymal Transition-Related Signaling Pathways in Prostate Cancer	38
The Value of H2BC12 for Predicting Poor Survival Outcomes in Patients With WHO Grade II and III Gliomas	38
Membrane Protein Activity Induces Specific Molecular Changes in Nanodiscs Monitored by FTIR Difference Spectroscopy	38
The Ubiquitin Ligase RNF34 Participates in the Peripheral Quality Control of CFTR (RNF34 Role in CFTR PeriQC)	38
Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development	38
Identifying Topics and Evolutionary Trends of Literature on Brain Metastases Using Latent Dirichlet Allocation	38
Development and Verification of a Hypoxic Gene Signature for Predicting Prognosis, Immune Microenvironment, and Chemosensitivity for Osteosarcoma	38
MicroRNA-125b-5p Correlates With Prognosis and Lung Adenocarcinoma Progression	37
Prospects of liquid biopsy in the prognosis and clinical management of gastrointestinal cancers	37
Virus sequencing performance during the SARS-CoV-2 pandemic: a retrospective analysis of data from multiple rounds of external quality assessment in Austria	37
Identification of IQGAP1 as a SLC26A4 (Pendrin)-Binding Protein in the Kidney	37
Mechanistic Insight Into Cadmium- and Zinc-Induced Inactivation of the Candida albicans Pif1 Helicase	37
Lipids and α-Synuclein: adding further variables to the equation	37
P53-Related Anticancer Activities of Drimia calcarata Bulb Extracts Against Lung Cancer	36
DEER Data Analysis Software: A Comparative Guide	36
Regulation mechanism of ferroptosis and its research progress in tumor immunotherapy	36
Engineering principles for rationally design therapeutic strategies against hepatocellular carcinoma	35
Focusing on Mechanoregulation Axis in Fibrosis: Sensing, Transduction and Effecting	35
Computational study of nitro-benzylidene phenazine as dengue virus-2 NS2B-NS3 protease inhibitor	35
Evolution of Indian Influenza A (H1N1) Hemagglutinin Strains: A Comparative Analysis of the Pandemic Californian HA Strain	35
The structural properties of full-length annexin A11	35
Characterizing cellular membrane partitioning of DMSO using low-temperature Raman spectroscopy	35
Mutations of CX46/CX50 and Cataract Development	35
Identification of a neuron-specific ferroptosis in the neurodegenerative mucopolysaccharidosis III model	34
FSCC: Few-Shot Learning for Macromolecule Classification Based on Contrastive Learning and Distribution Calibration in Cryo-Electron Tomography	34
Involvement of shedding induced by ADAM17 on the nitric oxide pathway in hypertension	34
Modeling interaction networks between host, diet, and bacteria predicts obesogenesis in a mouse model	34
Potential of Natural Alkaloids From Jadwar (Delphinium denudatum) as Inhibitors Against Main Protease of COVID-19: A Molecular Modeling Approach	34
Editorial: Molecular Insights Into Ligand-Receptor Interactions on the Cell Surface	34
Linking oxidative stress biomarkers to disease progression and antioxidant therapy in hypertension and diabetes mellitus	34
The structural and functional roles of the flavin cofactor FAD in mammalian cryptochromes	33
Bacterial extracellular vesicles: towards realistic models for bacterial membranes in molecular interaction studies by surface plasmon resonance	33
A perspective on Drosophila genetics and its insight into human neurodegenerative disease	33
Ssu72: a versatile protein with functions in transcription and beyond	33
Chromatin: the old and young of it	33
Editorial: Machine learning in computer-aided drug design	33
A dual-reporter LDLR system integrating fluorescence and luminescence for understanding LDLR regulation and facilitating drug discovery	33
Corrigendum: Systematic analysis of MCM3 in pediatric medulloblastoma via multi-omics analysis	32
Regulatory mechanisms triggered by enzyme interactions with lipid membrane surfaces	32
Implications of trimethylamine N-oxide (TMAO) and Betaine in Human Health: Beyond Being Osmoprotective Compounds	32
Genome-Wide Enhancer Analysis Reveals the Role of AP-1 Transcription Factor in Head and Neck Squamous Cell Carcinoma	32
Reference Standards for Newborn Screening of Metabolic Disorders by Tandem Mass Spectrometry: A Nationwide Study on Millions of Chinese Neonatal Populations	32
Editorial: Allosteric functions and inhibitions: structural insights	32
Editorial: Tumorigenesis regulated by miRNAs, Volume II	32
Carbonic anhydrase versatility: from pH regulation to CO2 sensing and metabolism	32
Proteomic and Metabolomic Analyses of Right Ventricular Failure due to Pulmonary Arterial Hypertension	32
CIGB-300-Regulated Proteome Reveals Common and Tailored Response Patterns of AML Cells to CK2 Inhibition	31
A ferroptosis-related gene signature and immune infiltration patterns predict the overall survival in acute myeloid leukemia patients	31
Differential Expression of Serum TUG1, LINC00657, miR-9, and miR-106a in Diabetic Patients With and Without Ischemic Stroke	31
Mass Spectrometry-Based Targeted Serum Monomethylated Ribonucleosides Profiling for Early Detection of Breast Cancer	31
An Unbound Proline-Rich Signaling Peptide Frequently Samples Cis Conformations in Gaussian Accelerated Molecular Dynamics Simulations	31
Inteins as Drug Targets and Therapeutic Tools	31
Conformational Dynamics of DNA Polymerases Revealed at the Single-Molecule Level	31
Recent insights of obesity-induced gut and adipose tissue dysbiosis in type 2 diabetes	31
The underlying mechanism and targeted therapy strategy of miRNAs cross-regulating EMT process through multiple signaling pathways in hepatocellular carcinoma	31

Improved computational epitope profiling using structural models identifies a broader diversity of antibodies that bind to the same epitope	30
Comprehensive proteomics of monocytes indicates oxidative imbalance functionally related to inflammatory response in chronic kidney disease-related atherosclerosis	30
The role of cell membrane-coated nanoparticles as a novel treatment approach in glioblastoma	30
A randomized placebo−controlled clinical trial of oral green tea epigallocatechin 3−gallate on erythropoiesis and oxidative stress in transfusion−dependent β−thalassemia patients	30
Covalent fragment inhibits intramembrane proteolysis	30
Size of the protein-protein energy funnel in crowded environment	30
Mitochondria-Associated Membrane Scaffolding with Endoplasmic Reticulum: A Dynamic Pathway of Developmental Disease	30
Endotrophin as a risk marker of mortality and kidney complications in a type 1 diabetes cohort	30
Comprehensive analysis of juvenile idiopathic arthritis patients’ immune characteristics based on bulk and single-cell sequencing data	30
Circulating miR-206, miR-181b, and miR-21 as promising biomarkers in hypothyroidism and their relationship to related hyperlipidemia and hepatic steatosis	30
A Conserved Structural Role for the Walker-A Lysine in P-Loop Containing Kinases	29
The future of cancer treatment: combining radiotherapy with immunotherapy	29
Mechanisms of ferroptosis in chronic kidney disease	29
Characterization of cellular senescence patterns predicts the prognosis and therapeutic response of hepatocellular carcinoma	29
Heterologous investigation of metabotropic and ionotropic odorant receptors in ab3A neurons of Drosophila melanogaster	29
Development of anti-cancer drugs for tumor-associated macrophages: a comprehensive review and mechanistic insights	29
Mathematical Modeling of Proliferative Immune Response Initiated by Interactions Between Classical Antigen-Presenting Cells Under Joint Antagonistic IL-2 and IL-4 Signaling	29
Simulations of pH and thermal effects on SARS-CoV-2 spike glycoprotein	29
Prognostic Value of Oral Epstein–Barr Virus DNA Load in Locoregionally Advanced Nasopharyngeal Carcinoma	29
Cytotopic (Cyto-) IL-15 as a New Immunotherapy for Prostate Cancer: Recombinant Production in Escherichia coli and Purification	29
A comprehensive review of diagnostic approaches for hepatitis D	29
Development of a Polymerase Spiral Reaction-Based Isothermal Assay for Rapid Identification of Thrips palmi	28
Long-Term Cognitive Dysfunction in Cancer Survivors	28
Immunoglobulin A carries sulfated and O-acetylated N-glycans primarily at the tailpiece site – strategies for site-specific N-glycan identification	28
Emerging role of miRNAs in the regulation of ferroptosis	28
Predictive value analysis of the interaction network of Tks4 scaffold protein in colon cancer	28
The Functions of BET Proteins in Gene Transcription of Biology and Diseases	27
Combination of structure-based virtual screening, molecular docking and molecular dynamics approaches for the discovery of anti-prion fibril flavonoids	27
Evaluation of the OsTIR1 and AtAFB2 AID Systems for Genome Architectural Protein Degradation in Mammalian Cells	27
KODAMA exploratory analysis in metabolic phenotyping	27
Quantitative comparison of protein-protein interaction interface using physicochemical feature-based descriptors of surface patches	27
Identification of a polyamine-related signature and six novel prognostic biomarkers in oral squamous cell carcinoma	27
Cell-Target-Specific Anti-Inflammatory Effect of Empagliflozin: In Vitro Evidence in Human Cardiomyocytes	27
The cytosolic N-terminal domain of V-ATPase a-subunits is a regulatory hub targeted by multiple signals	27
Enhanced-Sampling Simulations for the Estimation of Ligand Binding Kinetics: Current Status and Perspective	27
Reduced platelet mitochondrial respiration and oxidative phosphorylation in patients with post COVID-19 syndrome are regenerated after spa rehabilitation and targeted ubiquinol therapy	27
Integrative Analysis of MALT1 as a Potential Therapeutic Target for Prostate Cancer and its Immunological Role in Pan-Cancer	27
Value of the 14-gene molecular assay in efficacy assessment of neoadjuvant chemoimmunotherapy for non-small cell lung cancer	27
Ubiquitylation Extends to Lipid Substrate for Restricting Bacterial Infection	27
In silico analysis of the HSP90 chaperone system from the African trypanosome, Trypanosoma brucei	26
Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling	26
Editorial: AI in Biological and Biomedical Imaging	26
Plasma enzymatic activity, proteomics and peptidomics in COVID-19-induced sepsis: A novel approach for the analysis of hemostasis	26
The permeation of potassium ions through the lipid scrambling path of the membrane protein nhTMEM16	26
Comprehensive analysis of hypoxia-related genes in diagnosis and immune infiltration in acute myocardial infarction: based on bulk and single-cell RNA sequencing data	26
Exploring Kv1.2 Channel Inactivation Through MD Simulations and Network Analysis	26
Recent progress of methods for cuproptosis detection	26
Phosphorylation Induced Conformational Transitions in DNA Polymerase β	26
A Novel Gene Signature Associated With “E2F Target” Pathway for Predicting the Prognosis of Prostate Cancer	26
Bioinformatic Analyses and Experimental Verification Reveal that High FSTL3 Expression Promotes EMT via Fibronectin-1/α5β1 Interaction in Colorectal Cancer	26
Proteomic Analysis of Cardiac Adaptation to Exercise by High Resolution Mass Spectrometry	26
Editorial: Dysregulated Protein Homeostasis in the Aging Organism	26
A Radiomics Signature-Based Nomogram to Predict the Progression-Free Survival of Patients With Hepatocellular Carcinoma After Transcatheter Arterial Chemoembolization Plus Radiofrequency Ablation	26
Deciphering the evolving niche interactome of human hematopoietic stem cells from ontogeny to aging	26
The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer	26
Mobile genetic element-encoded putative DNA primases composed of A-family polymerase—SSB pairs	26
Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysm	25
Editorial: Metalloproteins as sensors of gaseous small molecules—From bench to bed and beyond	25
Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus	25
CUX1 Facilitates the Development of Oncogenic Properties Via Activating Wnt/β-Catenin Signaling Pathway in Glioma	25
Discrete Biochemical Systems Theory	25
Metabolomic analysis of fatal hypothermia using ultra-high-performance liquid chromatography‒mass spectrometry	25
Editorial: Biomimetic and bioinspired membranes to reconstruct the properties of natural systems	25
Susceptibility of cervical cancer to dihydroartemisinin-induced ferritinophagy-dependent ferroptosis	25
Synergistic effects of mutation and glycosylation on disease progression	25
Noncovalent hyaluronan crosslinking by TSG-6: Modulation by heparin, heparan sulfate, and PRG4	25
Interventions in Nicotinamide Adenine Dinucleotide Metabolism, the Intestinal Microbiota and Microcin Peptide Antimicrobials	25
Editorial: Heterogeneity and plasticity of prostate cancer	25
Statistical Analysis of Protein-Ligand Interaction Patterns in Nuclear Receptor RORγ	25
Soluble guanylyl cyclase: Molecular basis for ligand selectivity and action in vitro and in vivo	25
Chinmedomics strategy for elucidating the effects and effective constituents of Danggui Buxue Decoction in treating blood deficiency syndrome	24
The Prognostic Value of Lysine Acetylation Regulators in Hepatocellular Carcinoma	24
Association between oral microbiome and seven types of cancers in East Asian population: a two-sample Mendelian randomization analysis	24
Identifying well-folded de novo proteins in the new era of accurate structure prediction	24
Acute changes in free and extracellular vesicle-associated circulating miRNAs and myokine profile in professional sky-runners during the Gran Sasso d’Italia vertical run	24
Free Energy Profiles Relating With Conformational Transition of the Switch Domains Induced by G12 Mutations in GTP-Bound KRAS	24
Upregulation of circ_0008812 and circ_0001583 predicts poor prognosis and promotes breast cancer proliferation	24
Misfolding of fukutin-related protein (FKRP) variants in congenital and limb girdle muscular dystrophies	24
Gender effect of glucose, insulin/glucagon ratio, lipids, and nitrogen-metabolites on serum HGF and EGF levels in patients with diabetes type 2	24
Advances and challenges in gene therapy strategies for pediatric cancer: a comprehensive update	24
Irisin reshapes bone metabolic homeostasis to delay age-related osteoporosis by regulating the multipotent differentiation of BMSCs via Wnt pathway	24
Microsecond melting and revitrification of cryo samples with a correlative light-electron microscopy approach	24
Refinement of SARS-CoV-2 envelope protein structure in a native-like environment by molecular dynamics simulations	24
Targeting Triple Negative Breast Cancer With Oncolytic Adenoviruses	24
Regulation of the HBV Entry Receptor NTCP and its Potential in Hepatitis B Treatment	24
Multi-omics characterization of the microbial populations and chemical space composition of a water kefir fermentation	24
5-methylcytosine turnover: Mechanisms and therapeutic implications in cancer	24
Carnitine O-octanoyltransferase (CROT) deficiency in mice leads to an increase of omega-3 fatty acids	24
Understanding blood development and leukemia using sequencing-based technologies and human cell systems	24
Risk factors of colorectal cancer in middle-aged and elder adults in China: findings from the China health and retirement longitudinal study	24
α-Synuclein in the Synaptic Vesicle Liquid Phase: Active Player or Passive Bystander?	24
Elevated expression of ANTXR1 gene in tumors is a poor prognostic biomarker for patients with bladder cancer	24
p53 and Zinc: A Malleable Relationship	23
Effect of sera from elite athletes on cytokine secretion and insulin signaling in preadipocytes and skeletal muscle cells	23
Editorial: Machine learning, epistasis, and protein engineering: From sequence-structure-function relationships to regulation of metabolic pathways	23