Biomedical Journal

Article	Citations
Living with tics: Nursing care of pediatric Tourette syndrome	180
Antrodia cinnamomea extract alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting the mTOR pathway	139
Roles of lncRNAs in the transcription regulation of HIV-1	132
Polycystic kidney disease increases the stoke incidence in Taiwan: A retrospective population-based cohort study using National Health Insurance Database	68
Hyperammonemia induces microglial NLRP3 inflammasome activation via mitochondrial oxidative stress in hepatic encephalopathy	68
One day at a time	50
Cell polarity regulators, multifunctional organizers of lymphocyte activation and function	44
Autonomic modulation and the risk of dementia in a middle-aged cohort: A 17-year follow-up study	43
The role of hypoxia-induced long noncoding RNAs (lncRNAs) in tumorigenesis and metastasis	42
Editorial Board	39
Aptamer-functionalized liposomes for drug delivery	39
When it doesn't run in the blood(vessels) – events involved in vascular disorders	38
Editorial Board	38
Editorial Board	36
We refuse to die – T cells causing havoc	35
Bilateral lentiform and caudate nucleus lesions in a child with COVID-19: A case report	35
m6A landscape is more pervasive when Trypanosoma brucei exits the cell cycle	34
Comprehensive insight into the alterations in the gut microbiome and the intestinal barrier as a consequence of iron deficiency anaemia	32
The establishment of a molecular diagnostic platform for mitochondrial diseases: From conventional to next-generation sequencing	32
The effects of macronutrients metabolism on cellular and organismal aging	31
Middle cerebral artery velocity is associated with the severity of MRI brain injury in neonates received therapeutic hypothermia	29
Tools to measure membrane potential of neurons	29
High-throughput proteomics-guided biomarker discovery of hepatocellular carcinoma	29
Implementation of fecal microbiota transplantation in a medical center for recurrent or refractory Clostridioides difficile infection and report of preliminary outcome	28
Eligibility for live, interactive otolaryngology telemedicine: 19-Month experience before and during the COVID-19 pandemic in Taiwan	28

Saliva as a diagnostic tool to measure polycyclic aromatic hydrocarbon exposure in dental patients exposed to intimate partner violence (IPV)	28
Lifestyle interventions to delay senescence	27
Influence of acupuncture twisting parameters on analgesic effects mediated by mast cells in AA rat models	25
Discharge status validation of the Chang Gung Research database in Taiwan	25
Glycolytic metabolism and activation of Na+ pumping contribute to extracellular acidification in the central clock of the suprachiasmatic nucleus: Differential glucose sensitivity and utilization betw	25
The binding and specificity of chemokine binding proteins, through the lens of experiment and computation	24
Using time-course as an essential factor to accurately predict sepsis-associated mortality among patients with suspected sepsis	23
Additional insights on SARS-CoV-2 spike protein variants and red blood cells biology	23
Advancements, challenges, and future prospects in clinical hyperpolarized magnetic resonance imaging: A comprehensive review	22
Circadian rhythmicity and human health	22
Grafted bone remodeling following transcrestal sinus floor elevation: A cone-beam computed tomography study	22
A panel of miRNAs in the serum extracellular vesicles serve as novel diagnostic biomarkers for MASLD	21
Automatic and human level Graf's type identification for detecting developmental dysplasia of the hip	20
Purinergic signaling: A new front-line determinant of resistance and susceptibility in leishmaniasis	20
Discrepant Treponemal Test Results: Identification of Associated Risk Factors Through Machine Learning Technology in 18-Year Electronic Medical Records and National Claims Data	20
Inhibition of NLRP3 attenuates sodium dextran sulfate-induced inflammatory bowel disease through gut microbiota regulation	20
Caffeic acid phenethyl ester inhibits the growth of bladder carcinoma cells by upregulating growth differentiation factor 15	19
Effect of three clinical therapies on cytokines modulation in the hip articular cartilage and bone improvement in rat early osteonecrosis of the femoral head	19
Repeated administration of adipose-derived mesenchymal stem cells added on beneficial effects of empagliflozin on protecting renal function in diabetic kidney disease rat	19
Long non-coding RNA HAGLROS facilitates the malignant phenotypes of NSCLC cells via repressing miR-100 and up-regulating SMARCA5	19
“Mpox in MSM: Tackling stigma, minimizing risk factors, exploring pathogenesis, and treatment approaches”	19
Sterile inflammation and the NLRP3 inflammasome in cardiometabolic disease	19
Low energy shock wave therapy attenuates mitochondrial dysfunction and improves bladder function in HCl induced cystitis in rats	18
Circ_0011385 knockdown inhibits cell proliferation, migration and invasion, whereas promotes cell apoptosis by regulating miR-330-3p/MYO6 axis in colorectal cancer	18
Fecal miRNAs as potential biomarkers for early detection of colorectal cancer: An updated review	18
Scaling the tips of the ALPS	18
Nod-like receptors in inflammatory arthritis	18
Angular super-resolution in X-ray projection radiography using deep neural network: Implementation on rotational angiography	17
Germline STAT3 gain-of-function mutations in primary immunodeficiency: Impact on the cellular and clinical phenotype	17
Surgery for metastatic epidural spinal cord compression in thoracic spine, anterior or posterior approach?	17
Comparing transvenous coiling and transarterial embolization with Onyx/NBCA for cavernous sinus dural arteriovenous fistulas: A retrospective study in a single center	17
Intravascular Large B-cell lymphoma: A case series and review of literatures	17
Multifunctional nanozymes for disease diagnosis and therapy	17
Structural, biochemical, and functional properties of the Rap1-Interacting Adaptor Molecule (RIAM)	17
A finger in every pie – The versatility of chemokines	17
Endothelial activation, cell-cell interactions, and inflammatory pathways in postoperative atrial fibrillation following cardiac surgery	17
Significant decrease of a master regulator of genes (REST/NRSF) in high-grade squamous intraepithelial lesion and cervical cancer	17
Hyperthermic intraperitoneal chemotherapy for recurrent epithelial ovarian cancer	16
Current efforts and challenges facing responses to Monkeypox in United Kingdom	16
SARS-CoV-2 variants – Evolution, spike protein, and vaccines	16
The incidence of resistance-associated variants to NS5A in HCV subtypes 1a and 1b in Taiwan	16
Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes	16
Advancing cancer diagnosis and treatment: Integrating molecular biomarkers and emerging technologies	16
Acquired Immune Deficiency Syndrome correlation with SARS-CoV-2 N genotypes	15
Circ_0091579 exerts an oncogenic role in hepatocellular carcinoma via mediating miR-136-5p/TRIM27	15
Clinical validation of a saliva-based matrix metalloproteinase-1 rapid strip test for detection of oral cavity cancer	15
Pharmacological therapy for Tourette syndrome: What medicine can do and cannot do	15
Clinical and functional characteristics of lung surgery-related vocal fold palsy	15
Response to "letter to editor" from Nicolini et al. Regarding "Autonomic modulation and the risk of dementia in a middle-aged cohort: A 17-year follow-up study"	15
Extracellular vesicles in fetal-maternal immune tolerance	15

Strides toward a better understanding of the “Current efforts and challenges facing responses to Monkeypox in United Kingdom”	15
Chronic low-dose REV-ERBs agonist SR9009 mitigates constant light-induced weight gain and insulin resistance via adipogenesis modulation	15
Ancient wisdom and modern innovations: Methods of administering healing	15
CAN008 prolongs overall survival in patients with newly diagnosed GBM characterized by high tumor mutational burden	15
Inherently imperfect, inherently evolving – The pursuit of precision through biomarkers	15
Joint effects of genomic markers and urinary methylation capacity associated with inorganic arsenic metabolism on the occurrence of cancers among residents in arseniasis-endemic areas: A cohort subset	15
The epidemiology of invasive fungal infections in transplant recipients	14
Mitochondrial dysfunction route as a possible biomarker and therapy target for human cancer	14
RASopathies: From germline mutations to somatic and multigenic diseases	14
Mouth opening/breathing is common in sleep apnea and linked to more nocturnal water loss	13
Altered diffusivity of the subarachnoid cisterns in the rat brain following neurological disorders	13
Utilizing nomograms to predict prevalent vertebral fracture risk: An analysis of dysmobility syndrome in a community-dwelling population	13
Clinical significance of incidental common bile duct dilatation in children: A 10-year single medical center experience	13
Targeted dexamethasone nano-prodrug for corneal neovascularization management	13
Editorial Board	13
The best protection is early detection	13
Macrophages of the Heart: Homeostasis and Disease	13
Autophagy-induced osteoblast-derived exosomes maintain bone formation and prevent osteoporosis by remodeling gut microbiota-metabolism	13
Phosphorylated α-synuclein in diluted human serum as a biomarker for Parkinson's disease	13
Author reply to letter to the editor “Imaging abnormalities in pediatric neuro-COVID are more diverse than specified”	13
Editorial Board	12
Comparison of the outcome of emergency endotracheal intubation in the general ward, intensive care unit and emergency department	12
Factors associated with pyloric hypertrophy severity and post-operative feeding and nutritional recovery in infantile hypertrophic pyloric stenosis	12
A comprehensive overview of gastric cancer management from a surgical point of view	12
Phylogenetic characteristics of Non-SARS human coronavirus in southern Taiwan, 2012–2013	12
Typical and atypical enteropathogenic Escherichia coli in children with acute diarrhoea: Changing trend in East Delhi	12
A CD33 frameshift variant is associated with neuromyelitis optica spectrum disorders	12
Glomerular disease classification and lesion identification by machine learning	12
Blood oxygenation state in COVID-19 patients: Unexplored role of 2,3-bisphosphoglycerate	12
Prognosis of chronic kidney disease in patients with non-alcoholic fatty liver disease: a Northeastern Taiwan community medicine research cohort	12
Biological functions of extracellular vesicles from mammalian cells	12
Infection control operations of a large hospital in Taiwan to prevent nosocomial outbreaks during COVID-19 pandemic	12
Editorial Board	11
Immunosenescence, gut dysbiosis, and chronic kidney disease: Interplay and implications for clinical management	11
Editorial Board	11
Complementary effects of Orthosiphon stamineus standardized ethanolic extract and rosmarinic acid in combination with gemcitabine on pancreatic cancer	11
Practical applications of grounding to support health	11
Negative regulatory NLRs mitigate inflammation via NF-κB pathway signaling in inflammatory bowel disease	11
Curcumin suppresses RANKL-induced osteoclast precursor autophagy in osteoclastogenesis by inhibiting RANK signaling and downstream JNK-BCL2-Beclin1 pathway	11
LncRNAs and asymmetric cell division: The epigenetic mechanisms	11
Genomic surveillance of SARS-CoV-2 in Taiwan: A perspective on evolutionary data interpretation and sequencing issues	11
The clockwork macrophage: timing in innate immunity	11
COVID-19 vaccination uptake strongly predicts averted deaths of older people across Europe	11
ShinySC: an R/Shiny-based desktop application for seamless analysis of scRNA-Seq data	11
Editorial Board	10
Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction	10
Antibody induction in mice by liposome-displayed recombinant enterotoxigenic Escherichia coli (ETEC) colonization antigens	10
The 2022 nobel prize in physiology or medicine awarded for the decoding of the complete ancient human genome	10
SLC7A11-HSPB1 Axis: A Novel Mechanism for Hepatocellular Carcinoma Progression and Ferroptosis Regulation	10
A review for cell and particle tracking on microscopy images using algorithms and deep learning technologies	10
The role of endocytic trafficking in antigen T cell receptor activation	10
Kinship analysis of type 2 diabetes mellitus familial aggregation in Taiwan	10
Gut mycobiome in metabolic diseases: Mechanisms and clinical implication	10
Effects of light, electromagnetic fields and water on biological rhythms	10
Real-world effectiveness of intravitreal dexamethasone implants - Comparison between eyes eligible and ineligible for clinical trials and their associated outcomes	9
Interferon-alpha and MxA inhibit BK polyomavirus replication by interaction with polyomavirus large T antigen	9
Small and mighty – microRNAs pulling the strings	9
Clinical studies on coronavirus disease 2019 (COVID-19) in the WHO registry network	9
BrainView: A Cloud-based Deep Learning System for Brain Image Segmentation, Tumor Detection and Visualization	9
Editorial Board	9
The next generation of healthcare ecosystem in the metaverse	9
Dilemmas in managing acute myocardial infarction during Covid-19 pandemic	9
Applications of three-dimensional imaging techniques in craniomaxillofacial surgery: A literature review	9
Genome-wide association study identifies DRAM1 associated with Tourette syndrome in Taiwan	9
Techniques to evaluate surfactant activity for a personalized therapy of RDS neonates	9
Novel approach by natural language processing for COVID-19 knowledge discovery	9
Apremilast ameliorates acute respiratory distress syndrome by inhibiting neutrophil-induced oxidative stress	8
Role of purinoreceptors in the release of extracellular vesicles and consequences on immune response and cancer progression	8
Differential longitudinal effects of frequent sweetened food consumption at different exposure ages on child cognitive, language, and motor development	8
SARS-CoV-2 pandemics: An update of CRISPR in diagnosis and host–virus interaction studies	8
LncRNA OIP5-AS1 reduces renal epithelial cell apoptosis in cisplatin-induced AKI by regulating the miR-144-5p/PKM2 axis	8
An area of greatest vulnerability - Recent advances in kidney injury	8
Modification of brain waves and sleep parameters by Citrus reticulata Blanco. cv. Sai-Nam-Phueng essential oil	8
c-MYC/METTL3/LINC01006 positive feedback loop promotes migration, invasion and proliferation of non-small cell lung cancer	8
MicroRNAs (−146a, −21 and −34a) are diagnostic and prognostic biomarkers for diabetic retinopathy	8
The efficacies of non-bismuth containing quadruple therapies in the treatment of first-line anti-Helicobacter pylori across 4-year time interval with changing antibiotics resistance	8
Serum CA-125 and renal impairment in patients undergoing hyperthermic intraperitoneal chemotherapy	8
Human adenovirus infections in pediatric population - An update on clinico–pathologic correlation	8
Different impacts of common risk factors associated with thrombocytopenia in patients with hepatitis B virus and hepatitis C virus infection	8
Deep learning significantly boosts CRT response prediction using synthetic longitudinal strain data: Training on synthetic data and testing on real patients	8

The International Week of Surfactant Research: Increasing knowledge about surfactant and unexploited opportunities	8
Increased macrophage activation marker soluble CD163 is associated with graft dysfunction and metabolic derangements in renal transplant recipients	8
Afterhyperpolarization potential modulated by local [K+]o in K+ diffusion-restricted extracellular space in the central clock of suprachiasmatic nucleus	7
Percentage genome change and chromosome 7q amplification predict sorafenib response in advanced hepatocellular carcinoma	7
Hepatocyte nuclear factor 4 located in different developmental stages of Schistosoma japonicum and involved in important metabolic pathways	7
Basic implications on three pathways associated with SARS-CoV-2	7
Palatal hybrid surgery for obstructive sleep apnea-state-of-the-art annotation of uvulopalatopharyngoplasty	7
Editorial Board	7
Using A modified quickert procedure combined with prolapsed fat and preseptal orbicularis muscle removal to correct involutional lower eyelid entropion in Asians	7
Impact of fasting & ketogenic interventions on the NLRP3 inflammasome: A narrative review	7
Reading the epitranscriptome of the human malaria parasite	7
Rhythms under tension: Circadian clocks in an Unsynced Society	7
Mitochondrial bioenergetics deficiency in cisd-1 mutants is linked to AMPK-mediated lipid metabolism	7
Disposition of embryos from women who only produced morphologically poor embryos on day three	7
Mutations in circulating tumor DNA detected in the postoperative period predict poor survival in patients with ovarian cancer	7
Comprehensive functional genomic analyses link APC somatic mutation and mRNA-miRNA networks to the clinical outcome of stage-III colorectal cancer patients	7
Effects of Rosa damascena on reproductive improvement, metabolic parameters, liver function and insulin-like growth factor-1 gene expression in estradiol valerate induced polycystic ovarian syndrome i	6
miRNA-mediated regulation of clock gene expression in men and women with colorectal cancer and possible consequences for disease management	6
The role of excess charge mitigation in electromagnetic hygiene: An integrative review	6
Strategies to protect surfactant and enhance its activity	6
Correlation of SALL1 with CEUS Parameters and Immune Escape in Thyroid Carcinoma	6
Editorial Board	6
Cartilage-specific knockout of miRNA-128a expression normalizes the expression of circadian clock genes (CCGs) and mitigates the severity of osteoarthritis	6
COVID-19 fatal outcomes: Role of the endothelial glycocalyx in both cell adhesion and migration	6
Differential bicistronic gene translation mediated by the internal ribosome entry site element of encephalomyocarditis virus	6
Inherited immunodeficiencies associated with proximal and distal defects in T cell receptor signaling and co-signaling	6
Application of Solidago chilensis and laser improved the repair of burns in diabetic rats	6
Evaluation of recurrence risk in patients with papillary thyroid cancer through tumor-node-metastasis staging: A single-center observational study in Taiwan	6
The respiratory impacts of air pollution in children: Global and domestic (Taiwan) situation	6
Emerging mutation in SARS-CoV-2 spike: Widening distribution over time in different geographic areas	6
Prevention and treatment of COVID-19 infection by earthing	6
Reply: Serum CA-125 and renal impairment in patients undergoing hyperthermic intraperitoneal chemotherapy	6
Changing life styles for children with Tourette syndrome	6
TP53 common variants and interaction with PPP1R13L and CD3EAP SNPs and lung cancer risk and smoking behavior in a Chinese population	6
The role of gut fungi in Clostridioides difficile infection	6
Elastase Reduces Background Autofluorescence in ALK Fluorescence In Situ Hybridization Assays for Lung Cancers	6
A recipe for a good clinical pulmonary surfactant	6
Evaluation of clinical relevance and underlying pathology for hemodynamic compromise in acute small subcortical infarction using MRI-based neuroimaging markers	6
Postnatal intestinal mucosa and gut microbial composition develop hand in hand: A mouse study	6
Editorial Board	6
AIFM1, negatively regulated by miR-145-5p, aggravates hypoxia-induced cardiomyocyte injury	6
The effects of bone-substitute augmentation on treatment of osteoporotic intertrochanteric fractures	6
Editorial Board	6
The combination of low level laser therapy and efavirenz drastically reduces HIV infection in TZM-bl cells	6
MicroRNA-based signature for diagnosis and prognosis of colorectal cancer using residuum of fecal immunochemical test	6
Would foot arch development in children characterize a body maturation process? A prospective longitudinal study	6
In-vitro and in-vivo functional observation studies to establish therapeutic potential of alpha-ketoglutarate against methotrexate induced liver injury	6
Chronobioethics: Symphony of biological clocks observed by 7-day/24-h ambulatory blood pressure monitoring and cardiovascular health	6
Charting new territory: The Plasmodium falciparum tRNA modification landscape	6
After me, the deluge	5
He protec but he also attac – Inflammasomes swinging the sword	5
Immunogenicity of second booster-dose COVID-19 mRNA vaccine among older adults in Taiwan	5
High levels estradiol affect blastocyst implantation and post-implantation development directly in mice	5
Modified ELISA for antibody avidity evaluation: The need for standardization	5
Acupressure reduces the severity of restless legs syndrome in hemodialysis patients: A cluster-randomized crossover pilot study	5
High-fat diet-induced increase in glucocorticoids contributes to adipogenesis in obese mice	5
IRE1α-mediated endoplasmic reticulum stress response regulates oxidative damage in CYP4V2 deficient human retinal pigment epithelial cells	5
Personalized medicine: From diagnostic to adaptive	5
Integrating comprehensive genomic profiling in the management of oncology patients: applications and challenges in Taiwan	5
Increased risk of migraine among patients with hidradenitis suppurativa: A US multi-center cohort study	5
Clinical and laboratory predictors for disease progression in patients with COVID-19: A multi-center cohort study	5
The correlation of small fiber neuropathy with pain intensity and age in patients with Fabry's disease: A cross sectional study within a large Taiwanese family	5
Minimal invasive fixation following with radiotherapy for radiosensitive unstable metastatic spine	5
A newly designed Flexible Hydrated-Hardening Bone Graft (FHBG) promotes bone regeneration and in vivo calvarial repair	5
Development and validation of a deep-learning-based pediatric early warning system: A single-center study	5
LAMA5: A new pathogenic gene for non-syndromic cleft lip with or without cleft palate	5
Secreted proteins encoded by super enhancer-driven genes could be promising biomarkers for early detection of esophageal squamous cell carcinoma	5
ECG-surv: A deep learning-based model to predict time to 1-year mortality from 12-lead electrocardiogram	5
Y-chromosome genes associated with sertoli cell-only syndrome identified by array comparative genome hybridization	5
Unveiling the mycobiota: The fungal frontier of human health	5
Dynamic monitoring of kidney injury status over 3 days in the intensive care unit as a sepsis phenotype associated with hospital mortality and hyperinflammation	5
Regenerative medicine for male infertility: A focus on stem cell niche injury models	5
Suppression of MGAT3 expression and the epithelial–mesenchymal transition of lung cancer cells by miR-188-5p	5
Long non-coding RNA TTTY15 sponges miR-520a-3p to exacerbate neural apoptosis induced by cerebral ischemia/reperfusion via targeting IRF9 both in vivo and in vitro	4
Mpox: A narrative review on current knowledge	4
Cytidine deaminase enhances liver cancer invasion by modulating epithelial-mesenchymal transition via NFκB signaling	4
Pediatric care for children with developmental coordination disorder, can we do better?	4
Vomocytosis of Cryptococcus neoformans from Macrophages: from discovery to current understanding	4
Application of extended reality in pediatric neurosurgery: A comprehensive review	4
Altered purinergic P2X7 and A2B receptors signaling limits macrophage-mediated host defense in schistosomiasis	4
The ratio of remaining to expected small bowel length predicts enteral autonomy in pediatric patients with short bowel syndrome	4
Msi2 enhances muscle dysfunction in a myotonic dystrophy type 1 mouse model	4
Combined therapy with dapagliflozin and entresto offers an additional benefit on improving the heart function in rat after ischemia-reperfusion injury	4
The role and mechanism of CARD9 gene polymorphism in diseases	4
Gut microbiota and clinical response to immune checkpoint inhibitor therapy in patients with advanced cancer	4
Influence of electromagnetic fields on the circadian rhythm: Implications for human health and disease	4
Physical attributes of salivary calcium particles and their interaction with gingival epithelium	4
Study of polymethylmethacrylate/tricalcium silicate composite cement for orthopedic application	4
Clinical feature, image findings and outcome of hepatosplenic candidiasis in patients with acute myeloid leukemia	4
Protein network analysis and functional enrichment via computational biotechnology unravel molecular and pathogenic mechanisms of kidney stone disease	4
Long noncoding RNA TUG1 promotes malignant progression of osteosarcoma by enhancing ZBTB7C expression	4
Lipopeptides against COVID-19 RNA-dependent RNA polymerase using molecular docking	4
The synergy of 177Lu-FAPI-46 with tyrosine kinase inhibitor in a sarcoma patient-derived xenograft mouse model	4