Genes & Diseases

Article	Citations
Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice	1267
An in-depth analysis of the prognostic significance and potential clinical impact of Leupaxin in the immunotherapeutic treatment of esophageal squamous cell carcinoma	306
Ubiquitination and degradation of SIK2 by DNA-PKcs deficiency promote radiation-induced mitotic catastrophe	278
Expanded insights into the mechanisms of RNA-binding protein regulation of circRNA generation and function in cancer biology and therapy	168
Multi-omics analysis to identify CBR3-AS1-hsa-miR-145-5p-MAP3K5 pathway as a ferroptosis-related ceRNA network in benign prostatic hyperplasia	151
Autoantigenic peptide landscape of rheumatoid arthritis-associated HLA class II	150
Integrative analysis reveals the clinical utility of cancer-associated fibroblast-derived signature, and its implication for young-onset thyroid cancer	144
Development of an orally bioavailable selective inhibitor of the menin-MLL	125
Liver-brain axis with alcohol: Role of fibroblast growth factor 21 (FGF21)	116
Clinical management of a rare melanoma case arising from congenital melanocytic nevus	104
Wnt genes in colonic polyposis predisposition	102
BET inhibitors enhance the anti-cancer effect of etoposide by suppressing the MRN-ATM axis in the DNA damage response	91
DNA damage chemotherapeutic drugs suppress basal-like breast cancer growth by down-regulating the transcription of the FOXO1-KLF5 axis	90
Effects of extracellular vesicle-derived noncoding RNAs on pre-metastatic niche and tumor progression	88
Atm deficient zebrafish model reveals conservation of the tumour suppressor function and a role in fertility	87
Sex hormone-binding globulin impedes hepatocellular carcinoma growth via MERTK regulation	86
PTEN-induced putative kinase 1 regulates mitochondrial quality control and is essential for the maturation of human induced pluripotent stem cell-derived cardiomyocytes	84
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells	83
CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice	78
SLC27A5 inhibits cancer stem cells by inducing alternative polyadenylation of METTL14 in hepatocellular carcinoma	77
Perturbed microbial ecology in pediatric systemic lupus erythematosus: Evidence from the gut microbiome and serum metabolome	77
The molecular genetics of PI3K/PTEN/AKT/mTOR pathway in the malformations of cortical development	72
Exploring the role of FTO in preeclampsia pathogenesis: Insights into m6A modification and decidualization	71
lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology	67
Epigenetics: Mechanisms, potential roles, and therapeutic strategies in cancer progression	66

The implication of pyroptosis in cancer immunology: Current advances and prospects	63
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer	60
UCH-L1 down-regulates HER2 expression and increases lapatinib sensitivity by interacting with HSP90 in HER2-positive breast cancer	60
Intra-tumoral microbiota: Key modulators of tumor immunity and therapeutic potential	58
Up-regulated IL-36 expression promotes a pro-tumorigenic phenotype in pancreatic ductal adenocarcinoma	58
Mechanism of PARP inhibitor resistance and potential overcoming strategies	57
Patient-derived xenograft models: Current status, challenges, and innovations in cancer research	56
The role of TGF-β in the tumor microenvironment of pancreatic cancer	54
Tryptophan attenuates acute hypoxic stress-induced intestinal injury through the modulation of intestinal barrier integrity and gut microbiota homeostasis	54
Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis	53
Loss of homeostatic functions in microglia from a murine model of Friedreich's ataxia	53
Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination	53
LncRNA KCNQ1OT1: Molecular mechanisms and pathogenic roles in human diseases	52
The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer	52
DNA methylation drives a new path in gastric cancer early detection: Current impact and prospects	51
Development of a multicellular 3D-bioprinted microtissue model of human periodontal ligament-alveolar bone biointerface: Towards a pre-clinical model of periodontal diseases and personalized periodont	50
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization	49
Heavy mechanical force decelerates orthodontic tooth movement via Piezo1-induced mitochondrial calcium down-regulation	49
The USP7 protein interaction network and its roles in tumorigenesis	49
Mitochondrial transplantation in lung diseases: From mechanisms to application prospects	46
Hippo-YAP/TAZ signaling in breast cancer: Reciprocal regulation of microRNAs and implications in precision medicine	46
Disulfidptosis heterogeneity in breast cancer uncovers PTTG1IP as an actionable therapeutic target	45
EBF1 expressed in the dermal papilla regulates hair type and length	45
Alternative splicing of immune-related genes identifies breast cancer subtypes with differential immune cell infiltration	44
Sirolimus may improve bile excretion in ABCB11 mutants: A case report of a patient with bile salt export pump deficiency	43
Overactivation of histone deacetylases and EZH2 in Wilms tumorigenesis	43
MACF1 deficiency suppresses tooth mineralization through IGF1 mediated crosstalk between odontoblasts and ameloblasts	43
AAV6 as an effective gene delivery vector for prolonged transgene expression in intervertebral disc cells in vivo	42
HBV sL13H mutation impairs its surface antigen expression and ability to induce autophagy	41
PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells	40
A peptide-based assay discriminates individual antibody response to SARS-CoV-2	40
Haplotype-resolved assemblies of the MHC region in five widely used tumor cell lines	39
Co-localization of TAZ and H2A.Z up-regulates IL-6 expression in alveolar epithelial cells to polarize M2 cells to alleviate hypoxia-induced lung injury	39
PD-L1 expression and smoke exposure as biomarkers for optimizing adjuvant therapy for patients with resected limited-stage small-cell lung carcinoma	39
Deubiquitinase USP17 negatively regulates 3T3-L1 adipocyte differentiation via HDAC1	38
Tirzepatide, a dual GIP/GLP-1 receptor agonist, alleviates metabolic dysfunction-associated steatotic liver disease by reducing the expression of CD36 and OBP2A	38
A heterozygous N-terminal truncation mutation of NFKBIA results in an impaired NF-κB dependent inflammatory response	36
Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma	36
A focused transcriptomic analysis of the TP53-regulated genes identifies the GPI-anchored molecule-like protein (GML) as a favorable prognostic predictor of lung cancer	36
Single-cell analysis reveals the lncRNA-MEG3/miRNA-133a-3p/PRRT2 axis regulates skeletal muscle regeneration and myogenesis	35
BET in hematologic tumors: Immunity, pathogenesis, clinical trials and drug combinations	35
The miR-21-5p enriched in the apoptotic bodies of M2 macrophage-derived extracellular vesicles alleviates osteoarthritis by changing macrophage phenotype	34
Sex-dependent impact of Il6 deficiency in Parkinson's disease mice	34
The transcriptional regulators of virulence for Pseudomonas aeruginosa: Therapeutic opportunity and preventive potential of its clinical infections	34
Single-cell landscape analysis reveals distinct regression trajectories and novel prognostic biomarkers in primary neuroblastoma	34
Dynamic human retinal pigment epithelium (RPE) and choroid architecture based on single-cell transcriptomic landscape analysis	34
Identification and functional characterization of a novel nonsense mutation of CASR gene in a familial hypocalciuric hypercalcemia pedigree	33
Reduction of Atp5b protects mice from diet-induced obesity	33
Vault RNAs (vtRNAs): Rediscovered non-coding RNAs with diverse physiological and pathological activities	33
Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity	33

3′-UTR of the SARS-CoV-2 genome as a possible source of piRNAs	32
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis	31
The genomic and epigenomic landscape of iridocorneal endothelial syndrome	31
SPINOPHILIN: A multiplayer tumor suppressor	31
MPDZ variants associated with epilepsies and/or febrile seizures and the individualized genotype-phenotype correlation	30
Publisher’s Note	30
Bmp9 modulates cell proliferation and intercellular junctions in HERS during tooth root development	30
Targeting SAMHD1: To overcome multiple anti-cancer drugs resistance in hematological malignancies	29
Inhibition of VEGFR2 overcomes venetoclax-resistance in diffuse large B-cell lymphoma cells	29
Hypermethylation of the ALOX12 and CBS promoters in osteoporosis: Potential biomarkers for early diagnosis	29
Hypoxia-induced m6A demethylation promotes hepatocellular carcinoma progression by preventing the degradation of Gal-1 mRNA	29
Cerebral furin deficiency causes hydrocephalus in mice	28
CUDC-907 inhibits glioblastoma and enhances glioblastoma sensitivity to temozolomide by inhibiting DNA damage repair	28
Emerging role of SETD2 in the development and function of immune cells	28
The combination of SLC7A11 inhibitor and oridonin synergistically inhibits cervical cancer cell growth by decreasing the NADPH/NADP+ ratio	28
Unraveling the role of the WIPF1/ACTN4 complex in podosome formation of human placental EVTs: Insights into recurrent spontaneous abortion	28
A novel mutation in KDR is associated with retinal venous beading and cerebral cavernous malformation	28
New insights into the cardio-renal benefits of SGLT2 inhibitors and the coordinated role of miR-30 family	28
Pseudotyped lentiviral vectors: Ready for translation into targeted cancer gene therapy?	27
The therapeutic effect of nicotinamide riboside chloride on ameliorating alcohol-induced neuronal damage with a focus on mitochondrial unfolded protein response and mitophagy	27
The paradoxical functions of long noncoding RNAs in hepatocellular carcinoma: Implications in therapeutic opportunities and precision medicine	27
Immune patterns of the tumor microenvironment in PD-L1+ EGFR+ HNSCC patients received anti-PD-1 and EGFR-based neoadjuvant therapy	27
MAFA-expressing panniculus carnosus regulates skin twitching in mice	27
The 21-base pair deletion mutant Calpain3 does not inhibit wild-type Calpain3 activity	26
MiR-743a-5p regulates differentiation of myoblast by targeting Mob1b in skeletal muscle development and regeneration	26
Development of novel osteoarthritis therapy by targeting AMPK-β-catenin-Runx2 signaling	26
Hsa_circ_0007099 and PIP4K2A coexpressed in diffuse large B-cell lymphoma with clinical significance	26
Alantolactone inhibits proliferation, metastasis and promotes apoptosis of human osteosarcoma cells by suppressing Wnt/β-catenin and MAPKs signaling pathways	25
Restriction of YWHAB-mediated YAP cytoplasmic retention is a novel mechanism underlying stemness maintenance and chemoresistance in ovarian cancer peritoneal metastasis	25
Whole exome sequencing identifies KCNH7 variants associated with epilepsy in children	25
STIM1 promotes acquired resistance to sorafenib by attenuating ferroptosis in hepatocellular carcinoma	25
Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance	25
Lactate transporter MCT4 regulates the hub genes for lipid metabolism and inflammation to attenuate intracellular lipid accumulation in non-alcoholic fatty liver disease	25
Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stage I–III lung adenocarcinoma	25
Targeting PD-1/PD-L1 in cancer immunotherapy: An effective strategy for treatment of triple-negative breast cancer (TNBC) patients	25
Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy	24
Increased N6-methyladenosine is related to the promotion of the methyltransferase METTL14 in ovarian aging	24
HSP90B1 facilitates glioma radiotherapy resistance by regulating RhoC ubiquitin‒proteasome degradation	24
Targeting MYC: Multidimensional regulation and therapeutic strategies in oncology	24
Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 4	24
Dlc1 deletion activates the canonical Wnt pathway at an early stage and affects subsequent cardiac differentiation in mouse embryonic stem cells	24
Single-cell spatial transcriptomics in cardiovascular development, disease, and medicine	23
Unveiling the roles of SPP1+ macrophage and IGFBP2+ fibroblast in lung adenosquamous carcinoma through single-cell analysis	23
Context-dependent actions of STING pathway in colitis and associated colon cancer	23
Characterization of the molecular dysfunctions occurring in Aicardi-Goutières syndrome patients with mutations in ADAR1	23
CCDC86-BHLHE40-ATF3 axis promotes aerobic glycolysis and tumor development in glioma	23
Epigenetic regulation of SARS-Cov-2 spike protein modulates cellular viability and nascent RNA transcription in neuronal cells	22
Circulating fibroblasts present neutrophil-like features in severe COVID-19 cases revealed by single-cell landscape analyses	22
Downregulation of nc886 contributes to prostate cancer cell invasion and TGFβ1-induced EMT	22
Transcriptomic analysis identifies a pan-cancer association of IL27 expression with cancer prognosis and immune microenvironment	22
ScMicrobesAtlas: A comprehensive microbial atlas at single-cell resolution in human disease contexts	22
Reduced neutralization of SARS-CoV-2 B.1.617 variant by convalescent and vaccinated sera	22
Co-alteration of Myc and RTK-RAS pathways defines a liver-metastatic propensity and immune-cold subgroup of pancreatic adenocarcinoma	22
Upregulated Krüppel-like factor 5 promotes hepatocellular carcinoma progression by activating Wnt3a signaling	22
Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes	21
The regulatory role of CASZ1 in keratinocyte differentiation and skin barrier function in atopic dermatitis	21
Hydrogen sulfide-induced post-translational modification as a potential drug target	21
Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration	21
Deletion of heterogeneous nuclear ribonucleoprotein K in satellite cells leads to inhibited skeletal muscle regeneration in mice	21
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosis	21
The generation and use of animal models of osteosarcoma in cancer research	21
The germline genetics of mild-to-moderate penetrance: An intriguing role of PRAME in multiple carcinogenesis	21
AUTS2 expression within mammalian lineage: A predictor of neural networks involved in autism spectrum disorders	21
Nidogen: A matrix protein with potential roles in musculoskeletal tissue regeneration	21
MYH9: Structure, functions, and therapeutic implications in cancer and genetic disorders	21
Nucleolin promotes tumor growth in colorectal cancer by enhancing hnRNPA1-mediated PKM2 alternative splicing	20
A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosis	20
The emerging roles of small nucleolar RNAs, piwi-interacting RNAs, tRNA-derived small RNAs, and circular RNAs in the regulation of cardiac hypertrophy, ischemic heart disease, and heart failure	20
Ammonia-induced cell death patterns in glioblastoma: Immune landscape, prognostic signature, and therapeutic target identification	20
Purinergic signaling in osteoarthritis: Mechanistic insights into pathogenesis and therapeutic targeting	20
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead	20
Targeting UDP-α-d-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth	20
New insights into the suppression of inflammation and lipid accumulation by JAZF1	20
Regulation mechanism and pathogenic role of lncRNA plasmacytoma variant translocation 1 (PVT1) in human diseases	19
A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy	19
Blockage of SUMO E1 enzyme inhibits ocular lens fibrosis by mediating SMAD4 SUMOylation	19
The biogenesis and secretion of exosomes and multivesicular bodies (MVBs): Intercellular shuttles and implications in human diseases	19
GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus	19
Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia	19
Targeting glutamine metabolism enhances responses to platinum-based chemotherapy in triple-negative breast cancers (TNBC)	19

Mutations in GTPBP3 cause aberrant mitochondrial respiration associated with combined oxidative phosphorylation deficiency 23	19
Construction of a novel six-gene signature to predict tumour response to induction chemotherapy and overall survival in locoregionally advanced laryngeal and hypopharyngeal carcinoma	19
Corrigendum to “Pan-cancer analysis of MET mutation and its association with the efficacy of immune checkpoint blockade” [Genes & Dis 12 (2025) 101450]	18
The functions of FXYD family members in human health and disease	18
The key mediator of diabetic kidney disease: Potassium channel dysfunction	18
The LIFR-targeting small molecules EC330/EC359 are potent ferroptosis inducers	18
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer	18
Circulating and non-circulating proteins and nucleic acids as biomarkers and therapeutic molecules in ovarian cancer	18
N6-methyladenosine-modified circLPAR3 Drives Docetaxel Resistance in Prostate Cancer by Suppressing Ferroptosis Through the PCBP2/CHAC1 Axis	18
The impact of broad glutamine metabolism inhibition on the tumor microenvironment	18
CALR accelerates the growth of liver cancer cells by enhancing telomere activity via ARAF	18
Assessment of the transcriptomic consequences and MAU2 protein levels in edited induced pluripotent stem cells with NIPBL pathogenic variants	18
PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma	18
Liver HMGCS2 is critical in the maintenance of liver lipid homeostasis during fasting	18
Arhgap29 deficiency causes EEC like syndrome in mice	18
In vivo production of CAR T cell: Opportunities and challenges	18
Neurokinin-2 receptor antagonist SR48968 induced necroptosis of myeloid leukemia cells by calcium overload-driven reactive oxygen species accumulation	18
Nucleolus localization of SpyCas9 affects its stability and interferes with host protein translation in mammalian cells	18
Corrigendum to “Cellular senescence-driven transcriptional reprogramming of the MAFB/NOTCH3 axis activates the PI3K/AKT pathway and promotes osteosarcoma progression” [Genes & Diseases 11 (2024) 9	18
Identification of Novel Compound Heterozygous Variants of the PNPLA6 Gene in Oliver-McFarlane Syndrome with Concomitant Insulin Resistance	17
Ultra-conserved non-coding sequences within the FOXF1 enhancer are critical for human lung development	17
Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression	17
The role of regulators of RNA m6A methylation in lung cancer	17
Osteoarthritis versus psoriasis arthritis: Physiopathology, cellular signaling, and therapeutic strategies	17
The role of m6A RNA methylation in autoimmune diseases: Novel therapeutic opportunities	17
Genetic and immunologic characteristics of colorectal cancer patients with KRAS mutations and predictive significance of tumor immune microenvironment in adjuvant chemotherapy	17
Elevation of TRIM44 potentiates propagation of gastric cancer stem cells	17
Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment	17
Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways	17
Cardiac regeneration: Pre-existing cardiomyocyte as the hub of novel signaling pathway	17
A lncRNA MEG3 variant enhances telomerase activity by increasing DNA damage repair ability in human liver cancer stem cells	17
RETRACTED: Corrigendum to “Lipopolysaccharide-induced podocyte injury is regulated by calcineurin/NFAT and TLR4/MyD88/NF-κB signaling pathways through Angiopoietin-like protein 4” [Genes Dis DOI: 10.1	17
MMP-9 deficiency accelerates the progress of periodontitis	16
Isoleucyl-tRNA synthetase 2 promotes pancreatic ductal adenocarcinoma proliferation and metastasis by stabilizing β-catenin	16
Identification of immune cell infiltration pattern in diabetic nephropathy	16
Prognosis prediction and immune microenvironment features of breast cancer indicated by a cuproptosis-associated long non-coding RNA signature	16
The crosstalk between non-coding RNAs and oxidative stress in cancer progression	16
Emerging roles for fatty acid oxidation in cancer	16
Alterations in expression and localization of POMGNT1 in the APP/PS1 mouse model of Alzheimer's disease	16
A novel truncating variant in PRDM16 causes severe familial cardiomyopathy with variable clinical presentations	16
Novel virulence-related genes that contribute to clinical infections of Salmonella enteritidis	16
Comprehensive analysis and experimental verification of the role of mitochondrial dynamics-related genes in liver hepatocellular carcinoma	16
Genetics, epidemiology and management of clubfoot and related disorders	16
Biallelic inactivation of SDHA results in comorbidity of pediatric recurrent neuroblastoma and gastric stromal tumor	16
TMEM132E ablation suppresses tumor progression and restores tamoxifen sensitivity by inducing ERα expression in triple-negative breast cancer	16
The role of RGS12 in tissue repair and human diseases	16
Salt-inducible kinase 1 is a key gene in suppressing EVD68-induced asthma by modulating antiviral immunity	16
Nrf2: A key regulator in chemoradiotherapy resistance of osteosarcoma	16
Identification of TMEM217 as a novel prognostic biomarker and potential therapeutic target in acute myeloid leukemia	16
The role and potential therapeutic intervention of cellular senescence in intervertebral disc degeneration	15
Establishment of a mouse model of respiratory mycoplasma challenged intranasally combined intraperitoneally eliciting chronic inflammation and lung consolidation	15
XBP1 splicing contributes to endoplasmic reticulum stress-induced human islet amyloid polypeptide up-regulation	15
Deregulated miRNA clusters in ovarian cancer: Imperative implications in personalized medicine	15
Transcriptomic landscapes underlying response and resistance to HDAC inhibitor chidamide in triple-negative breast cancer	15
X26nt-mediated recruitment of eIF4A2 facilitates CCND1 translation to drive endothelial cell cycle progression	15
Deciphering the impact of SNAI1 gene on renal tubular cell proteome, nucleolar stress, ribosome biogenesis, senescence, DNA damage response, and focal adhesion dynamics	15
IL-17 signaling pathway in SPP1+ macrophages drives digestive tract cancer progression	15
MyoAAV-delivered sup-tRNA increases full-length dystrophin expression	15
OTX1 promotes TNBC cell proliferation and tumor growth through the ERK pathway	15
Breaking paradigms: Long non-coding RNAs forming gene fusions with potential implications in cancer	14
Identification of TP53 mutation-associated prognostic genes and investigation of the immune cell infiltration in patients with hepatocellular carcinoma	14
The implication of dendritic cells in lung diseases: Immunological role of toll-like receptor 4	14
Friend or foe for obesity: How hepatokines remodel adipose tissues and translational perspective	14
lncRNA POU3F3 promotes osteosarcoma progression through GPX4-modulated ferroptosis by interaction with IGF2BP2 to facilitate NRF2 mRNA stability	14
Predictive value of T cell receptor repertoire profiling for immunosuppressive therapy in severe aplastic anemia	14
Immune characteristics analysis reveals two key inflammatory factors correlated to the expressions of SARS-CoV-2 S1-specific antibodies	14
Genetic association analysis-based networks and classification of human UCP1 polymorphisms	14
Targeting CD47-SIRPα axis for Hodgkin and non-Hodgkin lymphoma immunotherapy	14
Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes	14
Profiling of histone H3 trimethylation and distinct epigenetic pattern of chromosome Y in the transformed bronchial epithelial cells induced by consecutive arsenic treatment	14
BET bromodomain inhibitor JQ1 regulates spermatid development by changing chromatin conformation in mouse spermatogenesis	14
Single-cell RNA sequencing in juvenile idiopathic arthritis	14
Endocrine therapy resistance of breast cancer: Important role of G protein-coupled estrogen receptor (GPER) and new therapeutic strategies	14
COVID-19 therapeutics: Clinical application of repurposed drugs and futuristic strategies for target-based drug discovery	14
A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis	14
High glucose promotes macrophage M1 polarization through miR-32/Mef2d/cAMP signaling pathway	13
Post-transcriptional regulation of DEAD-box RNA helicases in hematopoietic malignancies	13
Pan-cancer analysis of MET mutation and its association with the efficacy of immune checkpoint blockade	13
Correspondence (reply): The application conditions of false discovery rate control	13
ADAM8 inactivation modulates cellular component assembly gene expression in the mouse intervertebral disc	13
Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance	13
Studies on the fat mass and obesity-associated (FTO) gene and its impact on obesity-associated diseases	13
Corrigendum to “N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis” [Genes & Diseases 10 (2023) 554–567]	13
Performance analysis of markers for prostate cell typing in single-cell data	13
BAF45D regulates spinal cord neural stem/progenitor cell fate through the SMAD-PAX6 axis	13
The landscape of UBE2S in hepatocellular carcinoma: Prognostic significance, immuno-oncology feature and drug response	13
PDK1 promotes breast cancer progression by enhancing the stability and transcriptional activity of HIF-1α	13
Calcineurin in development and disease	13
EBV-Mir-BART5-5p targets p53 independent pathway in cytoplasm: Potential role in EBV lymphomagenesis	13
Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism	13
CCT2 enhances c-Myc stabilization to drive tumor progression and chemoresistance in head and neck squamous cell carcinoma	12
Epigenetic regulation of mesenchymal stem cell aging through histone modifications	12
Insights into the role of RNA m6A modification in the metabolic process and related diseases	12
The landscape of epigenetic regulation and therapeutic application of N6-methyladenosine modifications in non-coding RNAs	12
Multi-omics integration reveals potential stage-specific druggable targets in T-cell acute lymphoblastic leukemia	12