Genes & Diseases

Article	Citations
A patient with glycogen storage disease type IA combined with hepatic adenoma: A case report	648
Transcriptomic characterization of posterior capsule, anterior capsule, and femoral condylar tissue highlights tissue-specific microenvironments in knee osteoarthritis	335
Synergistic anti-tumor activity of ciclopirox olamine and metformin in triple-negative breast cancer	214
The same genomic variants in the first three exons of KANSL1 can be either benign or causative of Koolen-de Vries syndrome: Definition of a validation procedure	193
Elucidating the maternal and fetal metabolic and immune landscapes of gestational diabetes mellitus with a pan-organ transcriptomic atlas	98
Identifying functional subtypes and common mechanisms of rheumatoid arthritis and systemic lupus erythematosus	97
Patient-derived xenograft models: Current status, challenges, and innovations in cancer research	96
Fibroblast growth factor 8: Multifaceted Role in Development and Developmental Disorder	82
Targeting STARD4/EGFR axis inhibits growth and overcomes lenvatinib resistance in hepatocellular carcinoma	78
SIRT5 promotes the osteo-inductive potential of BMP9 by stabilizing the HIF-1α protein in mouse embryonic fibroblasts	74
Exogenous pyruvate is therapeutic against colitis by targeting cytosolic phospholipase A2	74
Aquaporin-3 promotes proliferation and inflammation in hepatocellular carcinoma	71
Monogenic deficiency in murine intestinal Cdc42 leads to mucosal inflammation that induces crypt dysplasia	71
CD36 promotes tubular ferroptosis by regulating the ubiquitination of FSP1 in acute kidney injury	71
Identification of cross-reactive CD8+ T cell receptors with high functional avidity to a SARS-CoV-2 immunodominant epitope and its natural mutant variants	69
DNA damage chemotherapeutic drugs suppress basal-like breast cancer growth by down-regulating the transcription of the FOXO1-KLF5 axis	64
Structure, function, and pathology of Neurexin-3	63
Development of an orally bioavailable selective inhibitor of the menin-MLL	61
PTEN-induced putative kinase 1 regulates mitochondrial quality control and is essential for the maturation of human induced pluripotent stem cell-derived cardiomyocytes	59
A novel structural variant of RET causes familial Hirschsprung's disease via nonsense-mediated mRNA decay	59
Etiological roles of core promoter variation in triple-negative breast cancer	56
lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology	55
MAL2 DNA methylation serves as a biomarker for the diagnosis and prognosis of glioma	55
Interplays of liver fibrosis-associated microRNAs: Molecular mechanisms and implications in diagnosis and therapy	53
Liver-brain axis with alcohol: Role of fibroblast growth factor 21 (FGF21)	53

PLSCR1 promotes apoptosis and clearance of retinal ganglion cells in glaucoma pathogenesis	48
EBV-Mir-BART5-5p targets p53 independent pathway in cytoplasm: Potential role in EBV lymphomagenesis	46
Transcriptomic analysis reveals the promotion of lymph node metastasis by Helicobacter pylori infection via upregulating chemokine (C-X-C motif) receptor 2 expression in gastric carcinoma	45
Wnt genes in colonic polyposis predisposition	45
Cancer exploits a late premetazoan gene module conserved in the human genome	45
BET inhibitors enhance the anti-cancer effect of etoposide by suppressing the MRN-ATM axis in the DNA damage response	43
Deletion of G protein-coupled receptor 116 enhances neutrophil function and aggravates lung injury in mice	43
Herpesviral interplay with peroxisome: An underexplored viral niche	43
Prevention and treatment of gerbil hepatitis E using the programmable CRISPR-Cas13d system	42
LncRNA HOTTIP facilitated tumor growth via stimulating the hnRNPA2B1/DKK1/Wnt/β-catenin regulatory axis in hepatocellular carcinoma	42
Resident to exhausted CD4+ T cell ratio is associated with the prognosis of gastric cancer	40
Transcriptomic and machine learning analyses identify hub genes of metabolism and host immune response that are associated with the progression of breast capsular contracture	39
Epigenetics: Mechanisms, potential roles, and therapeutic strategies in cancer progression	39
Insights into the role of RNA m6A modification in the metabolic process and related diseases	37
Integrative analysis of the transcriptome and metabolome reveals the importance of hepatokine FGF21 in liver aging	37
CYP3A5 unexpectedly regulates glucose metabolism through the AKT–TXNIP–GLUT1 axis in pancreatic cancer	36
The landscape of epigenetic regulation and therapeutic application of N6-methyladenosine modifications in non-coding RNAs	36
Multi-omics analysis to identify CBR3-AS1-hsa-miR-145-5p-MAP3K5 pathway as a ferroptosis-related ceRNA network in benign prostatic hyperplasia	36
Clinical management of a rare melanoma case arising from congenital melanocytic nevus	34
Role of lncRNA MALAT1 in UVA-induced corneal endothelial senescence	34
Post-transcriptional regulation of DEAD-box RNA helicases in hematopoietic malignancies	34
Low CXCR6 expression drives extracellular matrix remodeling and enhances cell proliferation in OSCC	34
Integrative analysis of the metabolomes and transcriptomes of Ebola virus-infected cells: Uncovering pathways related to hepatic apoptosis	33
Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis	33
MAFB-mediated CEBPA regulated human urothelium growth through Wnt/β-catenin signaling pathway	33
PinX1 suppresses cancer progression by inhibiting telomerase activity in cervical squamous cell carcinoma and endocervical adenocarcinoma	32
In situ transcriptomic analysis of spermatocytes in non-obstructive azoospermia reveals senescence-like states in arrested spermatocytes	31
Mitochondrial DNA editing: Key to the treatment of neurodegenerative diseases	31
Fact or fiction — Exploring resident mesenchymal stem cells in abdominal aortic aneurysm from multiple perspectives	31
Fibrous scaffolds loaded with BMSC-derived apoptotic vesicles promote wound healing by inducing macrophage polarization	31
CDK9 inhibitor elicits APC through a synthetic lethal effect in colorectal cancer cells	30
Analysis of mutations in Chinese patients with polycystic kidney disease by targeted exome sequencing	29
Functional impact of the head domain variants of DES (Desmin) on filament assembly	29
Iron promotes both ferroptosis and necroptosis in the early stage of reperfusion in ischemic stroke	29
Advances in single-cell sequencing technology in microbiome research	29
Simultaneous detection of methylation and genetic variations of BCR-ABL1 gene by nanopore Cas9-targeted sequencing	27
Peritoneal adipose stem cell-derived extracellular vesicles mediate the regulation of ovarian cancer cell proliferation and migration through EGFR-NF-κB signaling	27
FAM20C: A key protein kinase in multiple diseases	27
The MTMR11 variants identified in a short stature cohort compromise the dephosphorylation ability of MTM1 on SMAD5 to up-regulate BMP signaling	27
The mucolipidosis III-causing mutation in GNPTAB, c.1760G>C, disrupts the development of somites in rats	27
Pdgfrα+ stromal cells, a key regulator for tissue homeostasis and dysfunction in distinct organs	26
Coupled single-cell and bulk RNA-seq analysis reveals the engulfment role of endothelial cells in atherosclerosis	26
CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice	26
Roles of Setbp1 in developmental hematopoiesis and acute myeloid leukemia	26
Genetic feature diversity of KRAS-mutated colorectal cancer and the negative association of DNA mismatch repair deficiency relevant mutational signatures with prognosis	26
Corrigendum to “N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis” [Genes & Diseases 10 (2023) 554–567]	26
Pan-cancer analysis of MET mutation and its association with the efficacy of immune checkpoint blockade	25
PTPN18 promotes colorectal cancer progression by regulating the c-MYC-CDK4 axis	25
Endothelial DLC1 is dispensable for liver and kidney function in mice	25
TFE3-mediated neuroprotection: Clearance of aggregated α-synuclein and accumulated mitochondria in the AAV-α-synuclein model of Parkinson's disease	25

Phenotypic characterization of patients with activated PI3Kδ syndrome 1 presenting with features of systemic lupus erythematosus	25
Pancreatic stromal Gremlin 1 expression during pancreatic tumorigenesis	25
Identification of differently expressed mRNAs by peripheral blood mononuclear cells in Vogt-Koyanagi-Harada disease	24
Identification of rare PTCH1 nonsense variant causing orofacial cleft in a Chinese family and an up-to-date genotype-phenotype analysis	24
Sex hormone-binding globulin impedes hepatocellular carcinoma growth via MERTK regulation	24
The transcriptome of circulating cells indicates potential biomarkers and therapeutic targets in the course of hypertension-related myocardial infarction	24
Circ-Smad5 retards the G1/S transition of cell cycle via inhibiting the activity of wnt/lef/cyclind1 signaling in JB6 cells	23
Comparison of hepatic gene expression profiles between three mouse models of Nonalcoholic Fatty Liver Disease	23
Beclin-1/LC3-II dependent macroautophagy was uninfluenced in ischemia-challenged vascular endothelial cells	22
Ubiquitin ligase DTX3 empowers mutant p53 to promote ovarian cancer development	22
OXCT1 regulates NF-κB signaling pathway through β-hydroxybutyrate-mediated ketone body homeostasis in lung cancer	22
KRAB-ZFPs and cancer stem cells identity	22
Does burning fat make tumor immune hot? Discovery of CD47 overexpression by radiation induced fatty acid oxidation	21
MyD88 in macrophages protects against colitis via inhibiting the activation of NLRP3 inflammasome in epithelial cells	21
C-terminal tensin-like (CTEN) knockin alleviates cystic kidney defects in Tensin-1 knockout mice	21
Ubiquitination and degradation of SIK2 by DNA-PKcs deficiency promote radiation-induced mitotic catastrophe	21
Coactivator-associated arginine methyltransferase 1: A versatile player in cell differentiation and development	21
The inflammatory microenvironment and the urinary microbiome in the initiation and progression of bladder cancer	21
Akt3 promotes cancer stemness in triple-negative breast cancer through YB1-Snail/Slug signaling axis	21
Emerging roles of circular RNAs in stem cells	20
Loss of the emei tumor suppressor promotes tumorigenesis via the JNK and Hippo pathway	20
Curcumin modulates oxidative stress to inhibit pyroptosis and improve the inflammatory microenvironment to treat endometriosis	20
Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination	20
Steroid receptor coactivator-1: The central intermediator linking multiple signals and functions in the brain and spinal cord	20
MicroRNAs in adipose tissue fibrosis: Mechanisms and therapeutic potential	20
Inhibition of ALDH2 by disulfiram leads to synthetic lethality via ROS strikes twice in ARID1A-deficient cholangiocarcinoma	20
β-Arrestin 2 suppresses the activation of YAP by promoting LATS kinase activity	20
Pathogenic roles of long noncoding RNAs in melanoma: Implications in diagnosis and therapies	20
Atm deficient zebrafish model reveals conservation of the tumour suppressor function and a role in fertility	20
Dehydrozaluzanin C, a novel type of anti-bacterial agent which targets transporting proteins, Opp and OpuC	19
Anaplastic thyroid cancer: Genetic roles, targeted therapy, and immunotherapy	19
Profiling the m6A-regulated RNA expression patterns and alternative splicing features in esophageal carcinoma	19
X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl) phthalate-induced testis toxicity	19
Mutant rs189037 in ataxia-telangiectasia mutated gene had a negative association with metabolic syndrome but not cognitive decline in centenarians	19
CRISPR/Cas9 system and its applications in nervous system diseases	19
Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice	18
Correspondence (reply): The application conditions of false discovery rate control	18
Mesenchymal stromal cell-derived small extracellular vesicles modulate macrophage polarization and enhance angio-osteogenesis to promote bone healing	18
The key piece of the airway remodeling puzzle revealed—LIGHT signaling in the lung	18
Circulating miR-548c-3p possesses good diagnostic potential for metabolic syndrome	18
Myelin protein zero (P0)- and Wnt1-Cre marked muscle resident neural crest-derived mesenchymal progenitor cells give rise to heterotopic ossification in mouse models	18
Uncovering the prominent role of satellite cells in paravertebral muscle development and aging by single-nucleus RNA sequencing	18
The potential development of drug resistance in rheumatoid arthritis patients identified with p53 mutations	18
False discovery rate control in cancer biomarker selection	18
BAF45D regulates spinal cord neural stem/progenitor cell fate through the SMAD-PAX6 axis	18
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer	18
Mitophagy deficiency activates stimulator of interferon genes activation and aggravates pathogenetic cardiac remodeling	17
Cancer-associated fibroblasts derived fibronectin extra domain A promotes sorafenib resistance in hepatocellular carcinoma cells by activating SHMT1	17
Performance analysis of markers for prostate cell typing in single-cell data	17
Update on R-loops in genomic integrity: Formation, functions, and implications for human diseases	17
KCNMA1 promotes obesity-related hypertension: Integrated analysis based on genome-wide association studies	17
Elevated meteorin-like protein from high-intensity interval training improves heart function via AMPK/HDAC4 pathway	17
Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction	16
Expanded insights into the mechanisms of RNA-binding protein regulation of circRNA generation and function in cancer biology and therapy	16
Impact of the COVID-19 pandemic on lung cancer treatment and research	16
Mutational single nucleotide polymorphism rs198389 and demethylation promoted natriuretic peptide B gene transcription in heart failure caused by dilated cardiomyopathy	16
Inhibition of ITGA2 suppresses cervical tumorigenesis and metastasis by targeting the AKT/mTOR signaling pathway	16
Critical involvement of circular RNAs in virus-associated cancers	16
mTOR pathway: A key player in diabetic nephropathy progression and therapeutic targets	16
The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer	16
Decoding the impact of gut microbiota on heart failure	15
SLC27A5 inhibits cancer stem cells by inducing alternative polyadenylation of METTL14 in hepatocellular carcinoma	15
Concurrent PIEZO1 activation and ATP2B4 blockade effectively reduce the risk of cerebral malaria and inhibit in vitro Plasmodium falciparum multiplication in red blood cells	15
Cyclin G2, a novel target of sulindac to inhibit cell cycle progression in colorectal cancer	15
Genome-wide DNA methylome analysis reveals a critical role of methylation-dysregulated lncRNAs in autophagy regulation in glioblastoma	15
Effects of extracellular vesicle-derived noncoding RNAs on pre-metastatic niche and tumor progression	15
miR-106b as an emerging therapeutic target in cancer	15
Clinical heterogeneity of NLRP12-associated autoinflammatory diseases	15
Signaling pathways governing the behaviors of leukemia stem cells	15
Ferroptosis: An emerging therapeutic opportunity for cancer	15
Electrophysiological and histological study reveals hidden subclinical haploinsufficiency of Otof	15
Autophagy-related lncRNAs in tumor progression and drug resistance: A double-edged sword	15
Chlorpyrifos induces spermatogenic dysfunction via ferroptosis in Sertoli cells	15
Multi-omics integration reveals potential stage-specific druggable targets in T-cell acute lymphoblastic leukemia	15
Phase I trial of human umbilical cord-derived mesenchymal stem cells for treatment of severe bronchopulmonary dysplasia	15
Exploring biomarkers of MAPK pathway co-expression in lung adenocarcinoma and their functions based on machine learning algorithms and single-cell analysis	14
The regulatory role and mechanism of energy metabolism and immune response in head and neck cancer	14
Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism	14
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells	14
Research progress and the prospect of using single-cell sequencing technology to explore the characteristics of the tumor microenvironment	14

Oridonin and its derivatives for cancer treatment and overcoming therapeutic resistance	14
Novel discovery of PDPN-positive CAFs contributing to tumor-associated lymphangiogenesis through mesenchymal to lymphatic endothelial transition in intrahepatic cholangiocarcinoma	14
Mitochondrial diseases and mtDNA editing	14
Unique anti-angiogenic effects, pharmacological targets and therapeutic mechanisms of Chinese herbal medicines for endometriosis	14
Heterogeneity of anoikis in triple-negative breast cancer subtyping and therapeutic implications	14
The SUMO E3 ligase CBX4 is identified as a poor prognostic marker of gastric cancer through multipronged OMIC analyses	14
PDCD2 as a prognostic biomarker in glioma correlates with malignant phenotype	14
DEAD-box RNA helicases with special reference to p68: Unwinding their biology, versatility, and therapeutic opportunity in cancer	14
SFRP5 inhibits melanin synthesis of melanocytes in vitiligo by suppressing the Wnt/β-catenin signaling	13
Long noncoding RNA (lncRNA) HOTAIR: Pathogenic roles and therapeutic opportunities in gastric cancer	13
Mechanism of PARP inhibitor resistance and potential overcoming strategies	13
LOX upregulates FAK phosphorylation to promote metastasis in osteosarcoma	13
The role of TGF-β in the tumor microenvironment of pancreatic cancer	13
Targeting LIF/LIFR signaling in cancer	13
Endometrial stem/progenitor cells: Properties, origins, and functions	13
Genetic profiles of familial late-onset Alzheimer's disease in China: The Shanghai FLOAD study	13
Is there a potential of circulating miRNAs as biomarkers in rheumatic diseases?	13
CRISPR/CasRx-mediated RNA knockdown targeting β-catenin and Ihh signaling alleviates osteoarthritis	13
The implication of pyroptosis in cancer immunology: Current advances and prospects	13
Epigenetic regulation of mesenchymal stem cell aging through histone modifications	13
Crotonylation of PRKACA enhances PKA activity and promotes colorectal cancer development via the PKA-FAK-AKT pathway	13
Inflammation and cancer: paradoxical roles in tumorigenesis and implications in immunotherapies	13
Liver-specific Mettl3 ablation delays liver regeneration in mice	13
Advances of CRISPR-Cas13 system in COVID-19 diagnosis and treatment	13
Clinical applications of the CRISPR/Cas9 genome-editing system: Delivery options and challenges in precision medicine	13
Dynamic human retinal pigment epithelium (RPE) and choroid architecture based on single-cell transcriptomic landscape analysis	12
Transcriptomic analysis identifies the neuropeptide cortistatin (CORT) as an inhibitor of temozolomide (TMZ) resistance by suppressing the NF-κB-MGMT signaling axis in human glioma	12
Exploration of the common gene and potential molecular mechanisms between Herpes simplex virus 1 infection and Alzheimer's disease	12
Integrative transcriptome analysis identifies MYBL2 as a poor prognosis marker for osteosarcoma and a pan-cancer marker of immune infiltration	12
Molecular basis of fluoride toxicities: Beyond benefits and implications in human disorders	12
A cohort study on the A8G6 neutralizing antibody intranasal spray for preventing SARS-CoV-2 infection in healthcare workers	12
A novel in vitro prognostic model of bladder cancer based on urine-derived living tumor cells	12
Juvenile cardiomyopathy with dystrophin deficiency	12
The combination of methylenehydrofolate reductase C677T polymorphism screening and gastrointestinal tumor markers detection may be an early screening method for gastrointestinal cancer related to heli	12
Drugging IGF-1R in cancer: New insights and emerging opportunities	12
Tsc2 mutation induces renal tubular cell nonautonomous disease	12
Targeting RAS–RAF–MEK–ERK signaling pathway in human cancer: Current status in clinical trials	12
Durability of Hepatitis B surface antigen seroclearance in patients experienced nucleoside analogs or interferon monotherapy: A real-world data from Electronic Health Record	12
Bcl6 controls the stability and suppressive function of regulatory T cells in head and neck squamous cell carcinoma	12
Development of novel 5-FU modified siRNA against BCL-2 with enhanced efficacy and vehicle-free cellular uptake	12
Overactivation of histone deacetylases and EZH2 in Wilms tumorigenesis	12
Cell cycle dysregulation with overexpression of KIF2C/MCAK is a critical event in nasopharyngeal carcinoma	12
The molecular genetics of PI3K/PTEN/AKT/mTOR pathway in the malformations of cortical development	12
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics	12
Liquiritigenin promotes osteogenic differentiation and prevents bone loss via inducing auto-lysosomal degradation and inhibiting apoptosis	11
A novel acquired EGFR-SEPT14 fusion confers differential drug resistance to EGFR inhibitors in lung adenocarcinoma	11
DLX3 (Q178R) mutation delays osteogenic differentiation via H19/miR-29c-3p/KDM5B axis in TDO-iPSCs-derived MSCs	11
The role of glutathione S-transferases in human disease pathogenesis and their current inhibitors	11
ZRANB1 is an NBS1 deubiquitinase and a potential target to overcome radioresistance and PARP inhibitor resistance in triple-negative breast cancer	11
Bilirubin inhibits lung carcinogenesis by up-regulating cystatin A expression in tumor-infiltrating macrophages	11
Haplotype-resolved assemblies of the MHC region in five widely used tumor cell lines	11
Disulfidptosis heterogeneity in breast cancer uncovers PTTG1IP as an actionable therapeutic target	11
Bortezomib depended on PRDM1 and TP53 to exert therapeutic effect in activated B-cell-like diffuse large B-cell lymphoma	11
Otof gene transfer in DFNB9 mice carrying human founder non-truncating alleles	11
Novel function of biguanides in inhibition of phospholipase D1 expression via a translational mechanism in cancer cells	11
Integrated genomic analysis of EDNRB common and rare variants in Hirschsprung disease	11
Whole exome sequencing identifies new susceptibility candidates underlying community-acquired pneumonia	11
Targeting hypoxia-induced CBS expression inhibits breast cancer stem cells through the induction of ferroptosis	11
Menin facilitates the cell proliferation of bladder cancer via modulating the TFAP2C/β-catenin axis	10
Biallelic mutations in UGDH cause congenital microcephaly	10
The bidirectional effects of APPswe on the osteogenic differentiation of MSCs in bone homeostasis by regulating Notch signaling	10
Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses	10
The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer	10
Welander distal myopathy-associated TIA1 mutation exacerbates P-body and stress granule dynamics concomitant with nucleolar stress under oxidative stress	10
A prognostic model of patients with pancreatic cancer based on four N6-methyladenosine-related lncRNAs and analysis of related immune infiltration	10
TMEM249-mediated sperm hyperactivation is required for mouse fertility	10
Identification of POLQ as a chromosomal instability-associated biomarker for hepatocellular carcinoma	10
Genetically predicted blood metabolites mediate the association between immune cell characteristics and urolithiasis: A Mendelian randomization study and mediation analysis	10
An integrated genome-wide analysis identifies HUR/ELAVL1 as a positive regulator of osteogenesis through enhancing the β-catenin signaling activity	10
Transfer RNA-derived small RNAs (tsRNAs): A rising star in liquid biopsy	10
Comprehensive genomic analysis of early and late-onset hepatocellular carcinoma	10
Sirolimus may improve bile excretion in ABCB11 mutants:A case report of a patient with bile salt export pump deficiency	10
Establishment and characterization of an induced pluripotent stem cell line from a Japanese cystic fibrosis patient with homozygous 1540del10 CFTR mutation	9
Comprehensive identification and potential application of genetic alteration-driven enhancer RNAs for eRNA-targeted therapy in breast cancer	9
PTGS2 identified as a biomarker of glucocorticoid-induced osteonecrosis of the femoral head and an enhancer of osteogenesis	9
HER3: Unmasking a twist in the tale of a previously unsuccessful therapeutic pursuit targeting a key cancer survival pathway	9
Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs)	9
WITHDRAWN: ActRIIB small molecule inhibitor 2-67 ameliorates muscle atrophy in cancer cachexia by inhibiting the myostatin/Smad pathway	9
Argonaute (AGO) proteins play an essential role in mediating BMP9-induced osteogenic signaling in mesenchymal stem cells (MSCs)	9
M6A modification in cardiovascular disease: With a focus on programmed cell death	9
Activation of Wnt/β-catenin signaling in abdominal aortic aneurysm: A potential therapeutic opportunity?	9
Defective EMC1 drives abnormal retinal angiogenesis via Wnt/β-catenin signaling and may be associated with the pathogenesis of familial exudative vitreoretinopathy	9
Cardiac troponin I R193H mutant interacts with HDAC1 to repress phosphodiesterase 4D expression in cardiomyocytes	9
A heterozygous N-terminal truncation mutation of NFKBIA results in an impaired NF-κB dependent inflammatory response	9
A novel STK11 gene mutation (c.388dupG, p.Glu130Glyfs∗33) in a Peutz-Jeghers family and evidence of higher gastric cancer susceptibility associated with alterations in STK11 region aa 107-170	9
Integrated bioinformatics identifies the dysregulation induced by aberrant gene methylation in colorectal carcinoma	9
Promising prognostic value of ATP binding cassette transporters and their correlation with tumor-infiltrating immune cells in lung adenocarcinoma	9
Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma	9
Proteomic analysis of urinary exosomes reveals ferroptosis-associated proteins are involved in diabetic nephropathy	9
Targeting m6A modification inhibits herpes virus 1 infection	9
Autophagy in pulmonary fibrosis: friend or foe?	9
Single-cell analysis reveals the lncRNA-MEG3/miRNA-133a-3p/PRRT2 axis regulates skeletal muscle regeneration and myogenesis	9
Hypercalciuria switches Ca2+ signaling in proximal tubular cells, induces oxidative damage to promote calcium nephrolithiasis	8
LncRNA MIR31HG controls the proliferation and metastasis of gastric cancer by c-CBL-mediated degradation of β-catenin	8
Development of a multicellular 3D-bioprinted microtissue model of human periodontal ligament-alveolar bone biointerface: Towards a pre-clinical model of periodontal diseases and personalized periodont	8