Genes & Diseases

Article	Citations
Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice	1485
An in-depth analysis of the prognostic significance and potential clinical impact of Leupaxin in the immunotherapeutic treatment of esophageal squamous cell carcinoma	221
Ubiquitination and degradation of SIK2 by DNA-PKcs deficiency promote radiation-induced mitotic catastrophe	181
Phase separation of Snail1 modulates transcription and cancer progression	180
Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination	158
Expanded insights into the mechanisms of RNA-binding protein regulation of circRNA generation and function in cancer biology and therapy	131
Epigenetics: Mechanisms, potential roles, and therapeutic strategies in cancer progression	119
PTEN-induced putative kinase 1 regulates mitochondrial quality control and is essential for the maturation of human induced pluripotent stem cell-derived cardiomyocytes	119
Patient-derived xenograft models: Current status, challenges, and innovations in cancer research	113
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer	105
Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis	103
Mechanism of PARP inhibitor resistance and potential overcoming strategies	103
Autoantigenic peptide landscape of rheumatoid arthritis-associated HLA class II	101
The advancements in organoids: Potential and challenges in researching the esophagus and esophageal squamous cell carcinoma	100
Development of an orally bioavailable selective inhibitor of the menin-MLL	100
Multi-omics analysis to identify CBR3-AS1-hsa-miR-145-5p-MAP3K5 pathway as a ferroptosis-related ceRNA network in benign prostatic hyperplasia	93
The molecular genetics of PI3K/PTEN/AKT/mTOR pathway in the malformations of cortical development	91
Liver-brain axis with alcohol: Role of fibroblast growth factor 21 (FGF21)	90
Clinical management of a rare melanoma case arising from congenital melanocytic nevus	78
DNA damage chemotherapeutic drugs suppress basal-like breast cancer growth by down-regulating the transcription of the FOXO1-KLF5 axis	75
Wnt genes in colonic polyposis predisposition	75
Effects of extracellular vesicle-derived noncoding RNAs on pre-metastatic niche and tumor progression	71
Atm deficient zebrafish model reveals conservation of the tumour suppressor function and a role in fertility	70
Sex hormone-binding globulin impedes hepatocellular carcinoma growth via MERTK regulation	70
CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice	69

Perturbed microbial ecology in pediatric systemic lupus erythematosus: Evidence from the gut microbiome and serum metabolome	68
BET inhibitors enhance the anti-cancer effect of etoposide by suppressing the MRN-ATM axis in the DNA damage response	67
Integrating single-cell transcriptomics and machine learning to reveal prognostic and immune significance of lactylation in breast cancer	66
Inflammasome activation and signalling in the ischemic-reperfused myocardium	66
Optimized Yamanaka factors combined with TERT gene therapy for enhanced anti-aging effects	64
Tryptophan attenuates acute hypoxic stress-induced intestinal injury through the modulation of intestinal barrier integrity and gut microbiota homeostasis	64
The implication of pyroptosis in cancer immunology: Current advances and prospects	60
Exploring the role of FTO in preeclampsia pathogenesis: Insights into m6A modification and decidualization	60
lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology	57
SLC27A5 inhibits cancer stem cells by inducing alternative polyadenylation of METTL14 in hepatocellular carcinoma	56
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells	56
The role of TGF-β in the tumor microenvironment of pancreatic cancer	56
MACF1 deficiency suppresses tooth mineralization through IGF1 mediated crosstalk between odontoblasts and ameloblasts	55
LncRNA KCNQ1OT1: Molecular mechanisms and pathogenic roles in human diseases	53
Disulfidptosis heterogeneity in breast cancer uncovers PTTG1IP as an actionable therapeutic target	51
Sirolimus may improve bile excretion in ABCB11 mutants: A case report of a patient with bile salt export pump deficiency	49
Alternative splicing of immune-related genes identifies breast cancer subtypes with differential immune cell infiltration	49
Hippo-YAP/TAZ signaling in breast cancer: Reciprocal regulation of microRNAs and implications in precision medicine	49
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization	48
The miR-21-5p enriched in the apoptotic bodies of M2 macrophage-derived extracellular vesicles alleviates osteoarthritis by changing macrophage phenotype	47
DNA methylation drives a new path in gastric cancer early detection: Current impact and prospects	46
Heavy mechanical force decelerates orthodontic tooth movement via Piezo1-induced mitochondrial calcium down-regulation	46
Haplotype-resolved assemblies of the MHC region in five widely used tumor cell lines	46
HBV sL13H mutation impairs its surface antigen expression and ability to induce autophagy	45
PD-L1 expression and smoke exposure as biomarkers for optimizing adjuvant therapy for patients with resected limited-stage small-cell lung carcinoma	45
Co-localization of TAZ and H2A.Z up-regulates IL-6 expression in alveolar epithelial cells to polarize M2 cells to alleviate hypoxia-induced lung injury	45
A focused transcriptomic analysis of the TP53-regulated genes identifies the GPI-anchored molecule-like protein (GML) as a favorable prognostic predictor of lung cancer	44
Defective biological networks associated with pseudogene-derived lncRNAs in cancer drug resistance: Promising prospects for their clinical targets in cancer therapy	43
Dynamic human retinal pigment epithelium (RPE) and choroid architecture based on single-cell transcriptomic landscape analysis	42
Single-cell landscape analysis reveals distinct regression trajectories and novel prognostic biomarkers in primary neuroblastoma	42
Screening and validation of key metastasis-associated genes in pancreatic cancer using a multi-omics and machine learning approach	41
The transcriptional regulators of virulence for Pseudomonas aeruginosa: Therapeutic opportunity and preventive potential of its clinical infections	41
FAM151A inhibits hepatitis B virus by modulating cccDNA transcriptional activity	41
Histone modifications in cardiovascular diseases: Mechanisms and therapies	41
AAV6 as an effective gene delivery vector for prolonged transgene expression in intervertebral disc cells in vivo	40
Loss of homeostatic functions in microglia from a murine model of Friedreich's ataxia	39
BET in hematologic tumors: Immunity, pathogenesis, clinical trials and drug combinations	39
Overactivation of histone deacetylases and EZH2 in Wilms tumorigenesis	36
The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer	36
Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma	36
Single-cell analysis reveals the lncRNA-MEG3/miRNA-133a-3p/PRRT2 axis regulates skeletal muscle regeneration and myogenesis	35
Deubiquitinase USP17 negatively regulates 3T3-L1 adipocyte differentiation via HDAC1	35
EBF1 expressed in the dermal papilla regulates hair type and length	35
Tirzepatide, a dual GIP/GLP-1 receptor agonist, alleviates metabolic dysfunction-associated steatotic liver disease by reducing the expression of CD36 and OBP2A	35
Platinum-resistant ovarian cancer: From mechanisms to treatment strategies	34
Oncostatin M drives multifaceted immune pathogenesis in atopic dermatitis-like inflammation via neutrophil-dependent mechanisms	34
Reduction of Atp5b protects mice from diet-induced obesity	34
Development of a multicellular 3D-bioprinted microtissue model of human periodontal ligament-alveolar bone biointerface: Towards a pre-clinical model of periodontal diseases and personalized periodont	34
Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity	33
Integrative high-throughput studies to develop novel targets and drugs for the treatment of advanced prostate cancer	33

3′-UTR of the SARS-CoV-2 genome as a possible source of piRNAs	33
Bmp9 modulates cell proliferation and intercellular junctions in HERS during tooth root development	32
STIM1 promotes acquired resistance to sorafenib by attenuating ferroptosis in hepatocellular carcinoma	32
[18F]florbetapir PET for early detection of amyloidosis in patients with hereditary transthyretin amyloidosis polyneuropathy	32
Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stage I–III lung adenocarcinoma	32
Hsa_circ_0007099 and PIP4K2A coexpressed in diffuse large B-cell lymphoma with clinical significance	32
Publisher’s Note	31
A novel mutation in KDR is associated with retinal venous beading and cerebral cavernous malformation	31
Hypermethylation of the ALOX12 and CBS promoters in osteoporosis: Potential biomarkers for early diagnosis	31
Hypoxia-induced m6A demethylation promotes hepatocellular carcinoma progression by preventing the degradation of Gal-1 mRNA	31
The genomic and epigenomic landscape of iridocorneal endothelial syndrome	31
MPDZ variants associated with epilepsies and/or febrile seizures and the individualized genotype-phenotype correlation	31
The therapeutic effect of nicotinamide riboside chloride on ameliorating alcohol-induced neuronal damage with a focus on mitochondrial unfolded protein response and mitophagy	30
CUDC-907 inhibits glioblastoma and enhances glioblastoma sensitivity to temozolomide by inhibiting DNA damage repair	30
The 21-base pair deletion mutant Calpain3 does not inhibit wild-type Calpain3 activity	30
Two novel murine esophageal cancer cell line models exhibiting distinct sensitivities to immunotherapy	29
MiR-743a-5p regulates differentiation of myoblast by targeting Mob1b in skeletal muscle development and regeneration	29
Identification and functional characterization of a novel nonsense mutation of CASR gene in a familial hypocalciuric hypercalcemia pedigree	28
New insights into the cardio-renal benefits of SGLT2 inhibitors and the coordinated role of miR-30 family	28
Inhibition of VEGFR2 overcomes venetoclax-resistance in diffuse large B-cell lymphoma cells	28
The combination of SLC7A11 inhibitor and oridonin synergistically inhibits cervical cancer cell growth by decreasing the NADPH/NADP+ ratio	28
Development of novel osteoarthritis therapy by targeting AMPK-β-catenin-Runx2 signaling	27
Vault RNAs (vtRNAs): Rediscovered non-coding RNAs with diverse physiological and pathological activities	27
Pseudotyped lentiviral vectors: Ready for translation into targeted cancer gene therapy?	27
SOX4: A potential therapeutic target for liver disease	27
Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance	27
Cerebral furin deficiency causes hydrocephalus in mice	27
GBM-Dx SIGNAL: Blood transcriptomics complementing neuroimaging to differentiate glioblastoma recurrence from treatment effects	27
Emerging role of SETD2 in the development and function of immune cells	26
SPINOPHILIN: A multiplayer tumor suppressor	26
Targeting PD-1/PD-L1 in cancer immunotherapy: An effective strategy for treatment of triple-negative breast cancer (TNBC) patients	26
Restriction of YWHAB-mediated YAP cytoplasmic retention is a novel mechanism underlying stemness maintenance and chemoresistance in ovarian cancer peritoneal metastasis	26
Unraveling the role of the WIPF1/ACTN4 complex in podosome formation of human placental EVTs: Insights into recurrent spontaneous abortion	26
Targeting SAMHD1: To overcome multiple anti-cancer drugs resistance in hematological malignancies	26
Lactate transporter MCT4 regulates the hub genes for lipid metabolism and inflammation to attenuate intracellular lipid accumulation in non-alcoholic fatty liver disease	26
Upregulated Krüppel-like factor 5 promotes hepatocellular carcinoma progression by activating Wnt3a signaling	25
Co-alteration of Myc and RTK-RAS pathways defines a liver-metastatic propensity and immune-cold subgroup of pancreatic adenocarcinoma	25
Unveiling the roles of SPP1+ macrophage and IGFBP2+ fibroblast in lung adenosquamous carcinoma through single-cell analysis	25
Epigenetic regulation of SARS-Cov-2 spike protein modulates cellular viability and nascent RNA transcription in neuronal cells	25
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis	25
Deletion of heterogeneous nuclear ribonucleoprotein K in satellite cells leads to inhibited skeletal muscle regeneration in mice	24
Dlc1 deletion activates the canonical Wnt pathway at an early stage and affects subsequent cardiac differentiation in mouse embryonic stem cells	24
Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 4	24
Circulating fibroblasts present neutrophil-like features in severe COVID-19 cases revealed by single-cell landscape analyses	24
Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy	24
AUTS2 expression within mammalian lineage: A predictor of neural networks involved in autism spectrum disorders	24
The germline genetics of mild-to-moderate penetrance: An intriguing role of PRAME in multiple carcinogenesis	24
Ammonia-induced cell death patterns in glioblastoma: Immune landscape, prognostic signature, and therapeutic target identification	24
Targeting UDP-α-d-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth	24
Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes	23
IRF7-mediated microglia activation exacerbates temporal lobe epilepsy through targeting the neuronal RORB/STIM1 pathway	23
Hydrogen sulfide-induced post-translational modification as a potential drug target	23
Targeting glutamine metabolism enhances responses to platinum-based chemotherapy in triple-negative breast cancers (TNBC)	23
Glutamine homeostasis regulates PD-L1 level through STAT3 in pancreatic cancer	23
Nuclear factor I/A: A novel multifunctional player in bone homeostasis via coordinating osteoclast and osteoblast differentiation	23
Whole exome sequencing identifies KCNH7 variants associated with epilepsy in children	23
Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration	22
The emerging roles of small nucleolar RNAs, piwi-interacting RNAs, tRNA-derived small RNAs, and circular RNAs in the regulation of cardiac hypertrophy, ischemic heart disease, and heart failure	22
Low expression of OXCT1 promote colorectal cancer liver metastasis by upregulating CDK8 and β-catenin via H3 acetylation	22
Necroptosis-related diseases are regulated by the unfolded protein response during endoplasmic reticulum stress	22
Transcriptomic analysis identifies a pan-cancer association of IL27 expression with cancer prognosis and immune microenvironment	22
Purinergic signaling in osteoarthritis: Mechanistic insights into pathogenesis and therapeutic targeting	22
Increased N6-methyladenosine is related to the promotion of the methyltransferase METTL14 in ovarian aging	22
Characterization of the molecular dysfunctions occurring in Aicardi-Goutières syndrome patients with mutations in ADAR1	22
ScMicrobesAtlas: A comprehensive microbial atlas at single-cell resolution in human disease contexts	21
The regulatory role of CASZ1 in keratinocyte differentiation and skin barrier function in atopic dermatitis	21
A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosis	21
HSP90B1 facilitates glioma radiotherapy resistance by regulating RhoC ubiquitin‒proteasome degradation	21
CCDC86-BHLHE40-ATF3 axis promotes aerobic glycolysis and tumor development in glioma	21
Nidogen: A matrix protein with potential roles in musculoskeletal tissue regeneration	21
Regulation mechanism and pathogenic role of lncRNA plasmacytoma variant translocation 1 (PVT1) in human diseases	21
Reduced neutralization of SARS-CoV-2 B.1.617 variant by convalescent and vaccinated sera	20
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosis	20
Specific RNA structures and elements in the 5'-UTR of the SARS-CoV-2 genome and subgenomic RNA are critical for its infection	20
Parkinson's disease: When the gears of time stiffen — The life-and-death game of circadian rhythms, sleep disorders, and neurodegeneration	20
Liver HMGCS2 is critical in the maintenance of liver lipid homeostasis during fasting	20
Ultra-conserved non-coding sequences within the FOXF1 enhancer are critical for human lung development	20
Downregulation of nc886 contributes to prostate cancer cell invasion and TGFβ1-induced EMT	20
Critical roles of phosphorylation in multiple signaling pathways during the progression of osteoarthritis	20
New insights into the suppression of inflammation and lipid accumulation by JAZF1	20

Targeting MYC: Multidimensional regulation and therapeutic strategies in oncology	20
Cardiac regeneration: Pre-existing cardiomyocyte as the hub of novel signaling pathway	20
Genetic and immunologic characteristics of colorectal cancer patients with KRAS mutations and predictive significance of tumor immune microenvironment in adjuvant chemotherapy	20
A lncRNA MEG3 variant enhances telomerase activity by increasing DNA damage repair ability in human liver cancer stem cells	20
The biogenesis and secretion of exosomes and multivesicular bodies (MVBs): Intercellular shuttles and implications in human diseases	20
Nucleolin promotes tumor growth in colorectal cancer by enhancing hnRNPA1-mediated PKM2 alternative splicing	20
The generation and use of animal models of osteosarcoma in cancer research	20
Single-cell spatial transcriptomics in cardiovascular development, disease, and medicine	20
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead	20
Corrigendum to “Pan-cancer analysis of MET mutation and its association with the efficacy of immune checkpoint blockade” [Genes & Dis 12 (2025) 101450]	20
Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment	20
Circulating and non-circulating proteins and nucleic acids as biomarkers and therapeutic molecules in ovarian cancer	20
O-Glycosylation as an energy sensor: Related molecular mechanisms, disease associations, and therapeutic opportunities in type 2 diabetes	20
Elevation of TRIM44 potentiates propagation of gastric cancer stem cells	19
Neurokinin-2 receptor antagonist SR48968 induced necroptosis of myeloid leukemia cells by calcium overload-driven reactive oxygen species accumulation	19
Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression	19
SLC1A3 promotes survival and immune escape of pancreatic adenocarcinoma by regulating the JAK/STAT pathway	19
Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia	19
The LIFR-targeting small molecules EC330/EC359 are potent ferroptosis inducers	19
Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways	19
CALR accelerates the growth of liver cancer cells by enhancing telomere activity via ARAF	19
The role of m6A RNA methylation in autoimmune diseases: Novel therapeutic opportunities	18
Assessment of the transcriptomic consequences and MAU2 protein levels in edited induced pluripotent stem cells with NIPBL pathogenic variants	18
Construction of a novel six-gene signature to predict tumour response to induction chemotherapy and overall survival in locoregionally advanced laryngeal and hypopharyngeal carcinoma	18
Blockage of SUMO E1 enzyme inhibits ocular lens fibrosis by mediating SMAD4 SUMOylation	18
In vivo production of CAR T cell: Opportunities and challenges	18
Nucleolus localization of SpyCas9 affects its stability and interferes with host protein translation in mammalian cells	18
GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus	18
A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy	18
The impact of broad glutamine metabolism inhibition on the tumor microenvironment	18
Highly restricted specificity of aberrant exons in a saturated background of differentially expressed exons	18
Osteoarthritis versus psoriasis arthritis: Physiopathology, cellular signaling, and therapeutic strategies	18
The key mediator of diabetic kidney disease: Potassium channel dysfunction	18
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer	18
Epigenetic regulation mechanisms of DNMT1 in kidney diseases and prospects for targeted therapy	18
Arhgap29 deficiency causes EEC like syndrome in mice	18
The functions of FXYD family members in human health and disease	18
Corrigendum to “Cellular senescence-driven transcriptional reprogramming of the MAFB/NOTCH3 axis activates the PI3K/AKT pathway and promotes osteosarcoma progression” [Genes & Diseases 11 (2024) 9	18
PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma	18
N6-methyladenosine-modified circLPAR3 Drives Docetaxel Resistance in Prostate Cancer by Suppressing Ferroptosis Through the PCBP2/CHAC1 Axis	18
Mutations in GTPBP3 cause aberrant mitochondrial respiration associated with combined oxidative phosphorylation deficiency 23	17
Biallelic inactivation of SDHA results in comorbidity of pediatric recurrent neuroblastoma and gastric stromal tumor	17
Emerging roles for fatty acid oxidation in cancer	17
The role of regulators of RNA m6A methylation in lung cancer	17
Identification of immune cell infiltration pattern in diabetic nephropathy	16
Single-cell RNA sequencing in juvenile idiopathic arthritis	16
MyoAAV-delivered sup-tRNA increases full-length dystrophin expression	16
The landscape of UBE2S in hepatocellular carcinoma: Prognostic significance, immuno-oncology feature and drug response	16
Alterations in expression and localization of POMGNT1 in the APP/PS1 mouse model of Alzheimer's disease	16
Genetic association analysis-based networks and classification of human UCP1 polymorphisms	16
Prognosis prediction and immune microenvironment features of breast cancer indicated by a cuproptosis-associated long non-coding RNA signature	16
Profiling of histone H3 trimethylation and distinct epigenetic pattern of chromosome Y in the transformed bronchial epithelial cells induced by consecutive arsenic treatment	16
Transcriptomic landscapes underlying response and resistance to HDAC inhibitor chidamide in triple-negative breast cancer	16
IL-17 signaling pathway in SPP1+ macrophages drives digestive tract cancer progression	16
COVID-19 therapeutics: Clinical application of repurposed drugs and futuristic strategies for target-based drug discovery	16
X26nt-mediated recruitment of eIF4A2 facilitates CCND1 translation to drive endothelial cell cycle progression	16
A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis	15
Endocrine therapy resistance of breast cancer: Important role of G protein-coupled estrogen receptor (GPER) and new therapeutic strategies	15
Hematological and neurological expressed 1-mediated anoikis resistance promotes anaplastic thyroid cancer metastasis	15
Predictive value of T cell receptor repertoire profiling for immunosuppressive therapy in severe aplastic anemia	15
A novel truncating variant in PRDM16 causes severe familial cardiomyopathy with variable clinical presentations	15
Single-cell RNA sequencing reveals tumor microenvironment characteristics in ovarian malignant Brenner tumor	15
TMEM132E ablation suppresses tumor progression and restores tamoxifen sensitivity by inducing ERα expression in triple-negative breast cancer	15
Identification of TP53 mutation-associated prognostic genes and investigation of the immune cell infiltration in patients with hepatocellular carcinoma	15
Isoleucyl-tRNA synthetase 2 promotes pancreatic ductal adenocarcinoma proliferation and metastasis by stabilizing β-catenin	15
Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance	14
Deregulated miRNA clusters in ovarian cancer: Imperative implications in personalized medicine	14
Clinical and iPSC-based characterization of the HNF1A p.T82M variant	14
Microenvironmental heterogeneity and molecular features associated with lymphovascular invasion in pancreatic ductal adenocarcinoma	14
Breaking paradigms: Long non-coding RNAs forming gene fusions with potential implications in cancer	14
The role of RGS12 in tissue repair and human diseases	14
Comprehensive analysis and experimental verification of the role of mitochondrial dynamics-related genes in liver hepatocellular carcinoma	14
Salt-inducible kinase 1 is a key gene in suppressing EVD68-induced asthma by modulating antiviral immunity	14
MMP-9 deficiency accelerates the progress of periodontitis	14
High glucose promotes macrophage M1 polarization through miR-32/Mef2d/cAMP signaling pathway	14
OTX1 promotes TNBC cell proliferation and tumor growth through the ERK pathway	14
Genetics, epidemiology and management of clubfoot and related disorders	14
lncRNA POU3F3 promotes osteosarcoma progression through GPX4-modulated ferroptosis by interaction with IGF2BP2 to facilitate NRF2 mRNA stability	14
The implication of dendritic cells in lung diseases: Immunological role of toll-like receptor 4	14
PDK1 promotes breast cancer progression by enhancing the stability and transcriptional activity of HIF-1α	14
The TGF-β/SMAD4 signaling pathway promotes the progression of papillary thyroid cancer by regulating IGF2BP2-mediated m6A modification of SPRY1 mRNA	13
Nrf2: A key regulator in chemoradiotherapy resistance of osteosarcoma	13
Targeting hepatic CREBZF protects against atherosclerosis via exosomal miR-210-3p mediated inhibition of endothelial inflammation	13
Cardiovascular diseases as systemic modulators of oncogenesis: Mechanisms and clinical implications	13
EBV-Mir-BART5-5p targets p53 independent pathway in cytoplasm: Potential role in EBV lymphomagenesis	13
Identification of TMEM217 as a novel prognostic biomarker and potential therapeutic target in acute myeloid leukemia	13
Targeting CD47-SIRPα axis for Hodgkin and non-Hodgkin lymphoma immunotherapy	13
Studies on the fat mass and obesity-associated (FTO) gene and its impact on obesity-associated diseases	13
Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes	13
Correspondence (reply): The application conditions of false discovery rate control	13
5-Methylcytidine (m5C)-modified circSMAD2 promotes pancreatic cancer progression via the AKT/mTOR pathway	13
The crosstalk between non-coding RNAs and oxidative stress in cancer progression	13
Friend or foe for obesity: How hepatokines remodel adipose tissues and translational perspective	13
Calcineurin in development and disease	13
ADAM8 inactivation modulates cellular component assembly gene expression in the mouse intervertebral disc	13