OOIR: Observatory of International Research

Papers

(The H4-Index of Cellular and Molecular Gastroenterology and Hepatology is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Contents	183
Ptpn2: A Critical Regulator of Paneth Cell Homeostasis	83
NRF2 Controls the Competitive Fitness of Squamous Epithelial Cells in the Mouse Esophagus	83
Pathophysiological Roles of Ductular Reaction in Liver Inflammation and Hepatic Fibrogenesis	76
Cover	76
Location Matters: Mitochondrial Arginase 2 as a Treatment for Metabolic Disease?	72
Should I Stay or Should I Go – ERK as Control Lever in Hepatocyte Expansion	72
Mucosal-Associated Invariant T Cells in the Digestive System: Defender or Destroyer?	69
Development of Human Gut Organoids With Resident Tissue Macrophages as a Model of Intestinal Immune Responses	68
Gut-innervating TRPV1+ Neurons Drive Chronic Visceral Pain via Microglial P2Y12 Receptor	68
Autophagy Regulates Esophageal Epithelial Renewal	67
Interindividual Variation in Gut Nitrergic Neuron Density Is Regulated By GDNF Levels and ETV1	66
T Cell Repertoire Homogeneity and Blood-Gut Overlap in Patients With Inflammatory Bowel Disease	63
Macrophage Nogo-B Drives Liver Fibrosis	59
In Vivo Genome-Wide CRISPR Activation Screening Identifies Functionally Important Long Noncoding RNAs in Hepatocellular Carcinoma	59
New Immune Role for Axin1 in Colon Cancer Suppression	59
Loss of Brg1 and Pten in Pancreatic Ductal Cells Forms Intraductal Tubulopapillary Neoplasm via the YAP/TAZ Pathway	58
Targeting Ferroptosis Restores the Antiviral Activity of CD8+ T Cells During Chronic Hepatitis B Virus Infection	58
Long-term Temporal Stability of Peripheral Blood DNA Methylation Profiles in Patients With Inflammatory Bowel Disease	57
Contents	57
Role of Nox4 in Mitigating Inflammation and Fibrosis in Dextran Sulfate Sodium–Induced Colitis	54
Geranylgeranyl Pyrophosphate Promotes Hepatic Lipid Accumulation by Prenylation of Perilipin4	53
RBPJ Deficiency Sensitizes Pancreatic Acinar Cells to KRAS-Mediated Pancreatic Intraepithelial Neoplasia Initiation	53
Cover	49
Stratifin Is Necessary for Spasmolytic Polypeptide-Expressing Metaplasia Development After Acute Gastric Injury	48

The Placode Lineage Contributes to the Enteric Nervous System: A Caution for Cell Transplantation Therapy for Hirschsprung Disease	47
Liver-specific Bcl3 Knockout Alleviates Acetaminophen-induced Liver Injury by Activating Nrf2 Pathway in Male Mice	45
Glia Maturation Factor-β Supports Liver Regeneration by Remodeling Actin Network to Enhance STAT3 Proliferative Signals	44
PFKFB3-mediated Pro-glycolytic Shift in Hepatocellular Carcinoma Proliferation	44
HIRA in Hepatitis B Virus Minichromosome Regulation: Another Piece of the Puzzle	44
STIM1 Deficiency In Intestinal Epithelium Attenuates Colonic Inflammation and Tumorigenesis by Reducing ER Stress of Goblet Cells	43
Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model	42
A Dual-Compartment Scaffolding Role for RACK1 in Hepatic Glucagon Signaling and Gluconeogenesis	41
Trypsin-Mediated Sensitization to Ferroptosis Increases the Severity of Pancreatitis in Mice	40
Cover	40
The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation	40
NF-κB Inducing Kinase Attenuates Colorectal Cancer by Regulating Noncanonical NF-κB Mediated Colonic Epithelial Cell Regeneration	40
In vivo CRISPR Activation Screening, a Powerful Tool to Discover Oncogenic Driver Genes in Hepatocellular Carcinoma	39
Interplay of Gut Microbes and Aryl Hydrocarbon Receptor in Alcohol-Associated Liver Disease	38
Contents	38
Editorial Board	38
C-Reactive Protein, a Promising Approach for Acetaminophen Hepatotoxicity	38
Normalization of Cystic Fibrosis Immune System Reverses Intestinal Neutrophilic Inflammation and Significantly Improves the Survival of Cystic Fibrosis Mice	38