OOIR: Observatory of International Research

Papers

(The H4-Index of eBioMedicine is 79. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
A closer look at esophageal cancer through different lenses	404
Multifaceted autoimmunity: new challenges and new approaches	341
SLE and purine metabolizing ecto-enzymes	315
High level of plasma TILRR protein is associated with faster HIV seroconversion	297
Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupus	296
Corrigendum to “The significance of recurrent de novo amino acid substitutions that emerged during chronic SARS-CoV-2 infection: an observational study” [eBioMedicine, 2024;107:105273]	292
Erratum to “Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis” [EBioMedicine 49 (2019) 172–188]	261
Corrigendum to “PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis” [EBioMedicine 40 (2019) 290-304]	219
Same-day confirmation of infection and antimicrobial susceptibility profiling using flow cytometry	215
In SARS-CoV-2 delta variants, Spike-P681R and D950N promote membrane fusion, Spike-P681R enhances spike cleavage, but neither substitution affects pathogenicity in hamsters	200
Association of body composition with neuroimaging biomarkers and cognitive function; a population-based study of 70-year-olds	195
Corrigendum to “Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity” [eBioMedicine 109(2024) 105421]	194
Somatic hypermutation shapes the viral escape profile of SARS-CoV-2 neutralising antibodies	193
Machine learning detection of heteroresistance in Escherichia coli	190
Hypoxia activated HGF expression in pancreatic stellate cells confers resistance of pancreatic cancer cells to EGFR inhibition	190
Affordable blood culture systems from China: in vitro evaluation for use in resource-limited settings	189
Mechanotransduction as a therapeutic target for brain tumours	188
Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus	186
Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy	185
Forever chemicals: the persistent effects of perfluoroalkyl and polyfluoroalkyl substances on human health	184
T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19	176
Dilated Virchow Robin spaces in multiple sclerosis – a generalised marker of disease?	173
Effect of intra-partum azithromycin on the development of the infant nasopharyngeal microbiota: A post hoc analysis of a double-blind randomized trial	166
IBD metabonomics predicts phenotype, disease course, and treatment response	161
Gut microbiome and atrial fibrillation—results from a large population-based study	161

High serum C-X-C motif chemokine ligand 10 (CXCL10) levels may be associated with new onset interstitial lung disease in patients with systemic sclerosis: evidence from observational, clinical, transc	160
Genetic landscape of a large cohort of Primary Ovarian Insufficiency: New genes and pathways and implications for personalized medicine	157
Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis	154
Precision diagnostic approach to predict 5-year risk for microvascular complications in type 1 diabetes	144
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data	141
A pancreatic cancer risk prediction model (Prism) developed and validated on large-scale US clinical data	136
Elevated hippocampal copper in cases of type 2 diabetes	132
Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, pla	130
Ebola-Detect: A differential serodiagnostic assay for Ebola virus infections and surveillance in the presence of vaccine-induced antibodies	129
Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis	128
Quantitative stiffness assessment of cardiac grafts using ultrasound in a porcine model: A tissue biomarker for heart transplantation	128
Development of a translational inflammation panel for the quantification of cerebrospinal fluid Pterin, Tryptophan-Kynurenine and Nitric oxide pathway metabolites	127
A multiple sclerosis patient-oriented multiomics analysis tells us where to go next: Commentary for: “Alterations of host-gut microbiome interactions in multiple sclerosis”	126
Grandmaternal microchimerism: interesting curiosity or clinically relevant phenomenon?	126
A custom-made mouthguard reduces head acceleration during soccer heading and prevents acute electrophysiological and cognitive changes in amateur male players	125
Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern Europeans	116
Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer	116
Adults with Plasmodium falciparum malaria have higher magnitude and quality of circulating T-follicular helper cells compared to children	115
Daily variation in blood glucose levels during continuous enteral nutrition in patients on the intensive care unit: a retrospective observational study	115
Different oxytocin and corticotropin-releasing hormone system changes in bipolar disorder and major depressive disorder patients	114
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ	112
A computational framework to improve cross-platform implementation of transcriptomics signatures	111
Do interventions for mood improve inflammatory biomarkers in inflammatory bowel disease?: a systematic review and meta-analysis	106
Clinical and genetic characteristics of a large international cohort of individuals with rare NR5A1/SF-1 variants of sex development	106
Super-resolution ultrasound imaging reveals temporal cerebrovascular changes with disease progression in female 5×FAD mouse model of Alzheimer's disease: correlation with pathological impairments	103
NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe	103
Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster	103
Next-gen spinal cord injury clinical trials: lessons learned and opportunities for future success	102
Local fistula injection of allogeneic human amnion epithelial cells is safe and well tolerated in patients with refractory complex perianal Crohn's disease: a phase I open label study with long-term f	102
Resolving immune cells with patrolling behaviour by magnetic resonance time-lapse single cell tracking	97
The gene environment aetiology of freezing and its relationship with internalizing symptoms during adolescence	97
Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer	97
Phase 2a/b randomised placebo-controlled dose-escalation trial of triheptanoin for ataxia-telangiectasia: treating mitochondrial dysfunction with anaplerosis	97
Selective emergence of antibody-secreting cells in the multiple sclerosis brain	94
NR4A3 prevents diabetes induced atrial cardiomyopathy by maintaining mitochondrial energy metabolism and reducing oxidative stress	94
Desulfovibrio desulfuricans and its derived metabolites confer resistance to FOLFOX through METTL3	93
Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells	92
Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge model	90
Trajectories of olfactory identification preceding incident mild cognitive impairment and dementia: a longitudinal study	90
Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia	90
Patient-derived melanoma organoid models facilitate the assessment of immunotherapies	89
Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responses	89
Bi-allelic LAMP3 variants in childhood interstitial lung disease: a surfactant-related disease	89
Neurochemical signs of astrocytic and neuronal injury in acute COVID-19 normalizes during long-term follow-up	88
Can the level of copper in the hippocampus witness type-II diabetes versus Alzheimer's disease?	86
Reduced white matter microstructural integrity in prediabetes: Is early glucose dysmetabolism the culprit?	86
A comprehensive assessment of the association between common drugs and psychiatric disorders using Mendelian randomization and real-world pharmacovigilance database	86
The distinct genetic features of pancreatic cancer in Chinese population	86
Hippocampal overexpression of NOS1AP promotes endophenotypes related to mental disorders	85
Shifting microbiomes: pathobionts hiding in our guts	85

Association between hearing ability and cortical morphology in the elderly: multiparametric mapping, cognitive relevance, and neurobiological underpinnings	83
Widespread selenium deficiency in the brain of cases with Huntington's disease presents a new potential therapeutic target	83
SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum women	82
Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged	81
Predictive models of long COVID	79
Plasma epoxyeicosatrienoic acids and diabetes-related cardiovascular disease: The cardiovascular health study	79
Oral fungal profiling and risk of nasopharyngeal carcinoma: a population-based case-control study	79