OOIR: Observatory of International Research

Papers

(The TQCC of npj Microgravity is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars	157
A systematic review and meta-analysis of bone loss in space travelers	104
How does spaceflight affect the acquired immune system?	62
Update on the effects of microgravity on the musculoskeletal system	60
A review of alterations to the brain during spaceflight and the potential relevance to crew in long-duration space exploration	56
High intensity training during spaceflight: results from the NASA Sprint Study	49
Cardiovascular deconditioning during long-term spaceflight through multiscale modeling	46
Terrestrial health applications of visual assessment technology and machine learning in spaceflight associated neuro-ocular syndrome	45
The effects of microgravity on bone structure and function	40
Key points for the development of antioxidant cocktails to prevent cellular stress and damage caused by reactive oxygen species (ROS) during manned space missions	39
The influence of spaceflight and simulated microgravity on bacterial motility and chemotaxis	35
Gravity sensing in plant and animal cells	35
Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration	32
COVID-19—The largest isolation study in history: the value of shared learnings from spaceflight analogs	30
Macrophages in microgravity: the impact of space on immune cells	30
The effects of real and simulated microgravity on cellular mitochondrial function	29
Estimating medical risk in human spaceflight	27
Feasibility, potency, and safety of growing human mesenchymal stem cells in space for clinical application	26
Planetary extravehicular activity (EVA) risk mitigation strategies for long-duration space missions	22
Low-intensity vibration restores nuclear YAP levels and acute YAP nuclear shuttling in mesenchymal stem cells subjected to simulated microgravity	21
Effects of spaceflight aboard the International Space Station on mouse estrous cycle and ovarian gene expression	21
Reviving lower body negative pressure as a countermeasure to prevent pathological vascular and ocular changes in microgravity	20
Critical heat flux enhancement in microgravity conditions coupling microstructured surfaces and electrostatic field	20
Capillary flow of liquids in open microchannels: overview and recent advances	19
Regular exercise counteracts circadian shifts in core body temperature during long-duration bed rest	19

Hindlimb unloading causes regional loading-dependent changes in osteocyte inflammatory cytokines that are modulated by exogenous irisin treatment	18
Sessile volatile drop evaporation under microgravity	18
Quantitative magnetic resonance image assessment of the optic nerve and surrounding sheath after spaceflight	17
Overview of lunar dust toxicity risk	14
Modeled microgravity alters lipopolysaccharide and outer membrane vesicle production of the beneficial symbiont Vibrio fischeri	14
Nanopore sequencing at Mars, Europa, and microgravity conditions	14
Effects of exercise countermeasures on multisystem function in long duration spaceflight astronauts	14
Impact of convection on the damping of an oscillating droplet during viscosity measurement using the ISS-EML facility	14
3D cell culture using a clinostat reproduces microgravity-induced skin changes	14
Interactome of miRNAs and transcriptome of human umbilical cord endothelial cells exposed to short-term simulated microgravity	14
Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome	13
An advance in transfer line chilldown heat transfer of cryogenic propellants in microgravity using microfilm coating for enabling deep space exploration	13
Towards sustainable human space exploration—priorities for radiation research to quantify and mitigate radiation risks	13
Additive effects of simulated microgravity and ionizing radiation in cell death, induction of ROS and expression of RAC2 in human bronchial epithelial cells	13
Opposite response of blood vessels in the retina to 6° head-down tilt and long-duration microgravity	12
Findings from recent studies by the Japan Aerospace Exploration Agency examining musculoskeletal atrophy in space and on Earth	12
A way forward for fundamental physics in space	11
Characterization of amyloid β fibril formation under microgravity conditions	11
Demonstration of the effect of stirring on nucleation from experiments on the International Space Station using the ISS-EML facility	11
Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats	11
The ejection of large non-oscillating droplets from a hydrophobic wedge in microgravity	11
Six degrees head-down tilt bed rest caused low-grade hemolysis: a prospective randomized clinical trial	10
Is contact-line mobility a material parameter?	10
Microbial applications for sustainable space exploration beyond low Earth orbit	10
Robot-assisted surgery in space: pros and cons. A review from the surgeon’s point of view	10
Mitigating sarcoplasmic reticulum stress limits disuse-induced muscle loss in hindlimb unloaded mice	10
Nitrogen flow boiling and chilldown experiments in microgravity using pulse flow and low-thermally conductive coatings	10
How advances in low-g plumbing enable space exploration	10
Analysis of the effects of spaceflight and local administration of thrombopoietin to a femoral defect injury on distal skeletal sites	9
Mechanism for enhancing the growth of mung bean seedlings under simulated microgravity	9
Mechanical loading recovers bone but not muscle lost during unloading	9
Bone health in spacefaring rodents and primates: systematic review and meta-analysis	9
Improved feasibility of astronaut short-radius artificial gravity through a 50-day incremental, personalized, vestibular acclimation protocol	9
Ocular conditions and injuries, detection and management in spaceflight	9
Evaluating the effect of spaceflight on the host–pathogen interaction between human intestinal epithelial cells and Salmonella Typhimurium	9
Impairment of 7F2 osteoblast function by simulated partial gravity in a Random Positioning Machine	9
Mechanical deconditioning of the heart due to long-term bed rest as observed on seismocardiogram morphology	8
Equivalence of sessile droplet dynamics under periodic and steady electric fields	8
Detailed modelling of contact line motion in oscillatory wetting	8
Effects of microgravity exposure and fructo-oligosaccharide ingestion on the proteome of soleus and extensor digitorum longus muscles in developing mice	8
Diffusion in liquid mixtures	8
Human behavior and performance in deep space exploration: next challenges and research gaps	8
Scientific perspectives on lunar exploration in Europe	8
Single-bubble EHD behavior into water two-phase flow under electric-field stress and gravitational acceleration using PFM	7
Histone deacetylase HDA-4-mediated epigenetic regulation in space-flown C. elegans	7
Brain stimulation in zero gravity: transcranial magnetic stimulation (TMS) motor threshold decreases during zero gravity induced by parabolic flight	7
Oscillations of a soft viscoelastic drop	7
The draining of capillary liquids from containers with interior corners aboard the ISS	7