OOIR: Observatory of International Research

Papers

(The TQCC of npj Microgravity is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Establishing a method for the cryopreservation of viable peripheral blood mononuclear cells in the International Space Station	79
Corner angle effects on capillary rise along curved interior corners	77
MicroAge mission: experimental design and hardware for a bespoke culture system supporting tissue-engineered skeletal muscle	66
Cooling of a granular gas mixture in microgravity	63
A study on the stability of ritonavir form III processed in orbit and returned to Earth	57
Impacts of radiation exposure, hindlimb unloading, and recovery on murine skeletal muscle cell telomere length	57
Microgravity triggers ferroptosis and accelerates senescence in the MG-63 cell model of osteoblastic cells	48
Implications of sex differences in orthostatic tolerance during exposure to acute artificial gravity	45
Effect of microgravity on mechanical loadings in lumbar spine at various postures: a numerical study	40
Spaceflight exposome/microgravity effects on the psychoimmunoneuroendocrine system	39
The kidney, volume homeostasis and osmoregulation in space: current perspective and knowledge gaps	38
Vection underwater illustrates the limitations of neutral buoyancy as a microgravity analog	36
Enhanced assembly of bacteriophage T7 produced in cell-free reactions under simulated microgravity	36
Optic nerve sheath diameter and spaceflight: defining shortcomings and future directions	35
Dynamic changes in perivascular space morphology predict signs of spaceflight-associated neuro-ocular syndrome in bed rest	35
Abdominal LIPUS ameliorates simulated microgravity induced skeletal muscle atrophy via the gut-muscle axis	33
Weightlessness leads to an increase granulosa cells in the growing follicle	30
In vitro evidence of bubble-induced acoustic softening and Sanal flow choking in cardiovascular decompression	30
Effect of calcium oxalate microcrystals on kidney proximal tubule epithelial cell gene expression in microgravity	29
Microgravity-induced constraints on melanin bioproduction: investigating E. coli metabolic responses aboard the international space station	27
Amyloidogenesis via interfacial shear in a containerless biochemical reactor aboard the International Space Station	27
Paving the way to better understand the effects of prolonged spaceflight on operational performance and its neural bases	26
Virtual reality-based sensory stimulation preferences at Amundsen-Scott South Pole station in Antarctica	25
Management of corneal injuries in spaceflight and recommendations for planetary missions	25
Long-term microgravity experiments reveal a new mechanism for particle aggregation in suspension	25

Illumination optimization and low-power trapping of Limnospira indica PCC 8005 using bulk acoustic waves in microgravity	25
Demonstration of charge-hold-vent (CHV) and no-vent-fill (NVF) in a simulated propellent storage tank during tank-to-tank cryogen transfer in microgravity	25
Passive limitation of surface contamination by perFluoroDecylTrichloroSilane coatings in the ISS during the MATISS experiments	25
PI3K/AKT/mTOR pathway and c-Myc inhibit hepatocyte suspension under simulated microgravity	24
Space habitats for bioengineering and surgical repair: addressing the requirement for reconstructive and research tissues during deep-space missions	23
Brief Communication: Confocal microscopy of oral streptococcal biofilms grown in simulated microgravity using a random positioning machine	23
Effects of whole-body vibration or resistive-vibration exercise on blood clotting and related biomarkers: a systematic review	23
Effects of exercise countermeasures on multisystem function in long duration spaceflight astronauts	22
Comparison of clinostat control strategies to achieve simulated microgravity with uniform gravity vector distribution	22
Publisher Correction: Active matter in space	22
NASA GeneLab derived microarray studies of Mus musculus and Homo sapiens organisms in altered gravitational conditions	22
Substrate metabolism in male astronauts onboard the International Space Station: the ENERGY study	22
Potential regulatory modules to integrate microgravity signals into flowering pathways in Arabidopsis thaliana grown in space	22
Bisphosphonate conjugation enhances the bone-specificity of NELL-1-based systemic therapy for spaceflight-induced bone loss in mice	21
RNA-seq analysis in simulated microgravity unveils down-regulation of the beta-rhizobial siderophore phymabactin	20
Recovery of bone microarchitecture and density four years after spaceflight: two case studies	20
External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial	20
A moonshot for female astronaut health, a win for all astronauts and space exploration	20
Optical observations of thunderstorms from the International Space Station: recent results and perspectives	20
Transcriptomic evidence of erythropoietic adaptation from the International Space Station and from an Earth-based space analog	18
Free surface bubbly flow in an open capillary channel	18
Cryogenic helium subsurface pressurization in terrestrial and low-gravity: experiments and flow visualization	18
Label-free blood cell separation for space health monitoring using a portable blast cell biochip	18
Stem cells in space: microgravity effects on stem cell fate and implications for regenerative medicine	18
Simulated microgravity impairs human NK cell cytotoxic activity against space radiation-relevant leukemic cells	18
Synthetic biology for space exploration	18
Simulated lunar microgravity transiently arrests growth and induces osteocyte-chondrocyte lineage differentiation in human Wharton’s jelly stem cells	17
A biological and ethical assessment of whether humans could or should reproduce in space	17
Daily artificial gravity partially mitigates vestibular processing changes associated with head-down tilt bedrest	17
Enhancing the precision limits of interferometric satellite geodesy missions	17
Endothelial dysfunction markers and immune response indices in cosmonauts’ blood after long-duration space flights	17
The value of a spaceflight clinical decision support system for earth-independent medical operations	17
Effectiveness of caffeine and blue-enriched light on cognitive performance and electroencephalography correlates of alertness in a spaceflight robotics simulation	17
Modelling large scale artery haemodynamics from the heart to the eye in response to simulated microgravity	17
A systematic review of the cerebrovascular adaptations following exposure to spaceflight or ground-based analogs: lessons from human and animal studies	16
Survival strategies of Rhinocladiella similis in perchlorate-rich Mars like environments	16
Uncertainty analysis and performance evaluation of thermophysical property measurement of liquid Au in microgravity	16
Unlocking the potential: analyzing 3D microstructure of small-scale cement samples from space using deep learning	16
Modeling the risk of airborne transmission of respiratory viruses in microgravity	16
GLARE: discovering hidden patterns in spaceflight transcriptome using representation learning	16
Examining the influence of turbulence on viscosity measurements of molten germanium under reduced gravity	16
Hypergravity is more challenging than microgravity for the human sensorimotor system	16
Changes in real-world walking speed following 60-day bed-rest	16
The MyoGravity project to study real microgravity effects on human muscle precursor cells and tissue	15
Effects of caffeine and blue-enriched light on spare visual attention during simulated space teleoperation	15
Explainable machine learning identifies multi-omics signatures of muscle response to spaceflight in mice	15
Inspiration4 data access through the NASA Open Science Data Repository	14
Space-driven ROS in cells: a hidden danger to astronaut health and food safety	14
Mechanism of LEPR-mediated cholesterol metabolism involved in NK cell function suppression under simulated microgravity	14
How advances in low-g plumbing enable space exploration	14

Unraveling dispersion and buoyancy dynamics around radial A + B → C reaction fronts: microgravity experiments and numerical simulations	14
Resilience of otolithic reflex to gravitational changes	14
Microgravity crystallization of perdeuterated tryptophan synthase for neutron diffraction	14
Rare diseases and space health: optimizing synergies from scientific questions to care	14
Long-duration human spaceflight induces atrophy in the left ventricular papillary muscles	14
Scientific perspectives on lunar exploration in Europe	13
Early skeletal deteriorations following short-duration spaceflight	13
Response of cardiac pulse parameters in humans at various inclinations via 360° rotating platform for simulated microgravity perspective	13
Validated space radiation exposure predictions from earth to mars during Artemis-I	13
The effect of space travel on human reproductive health: a systematic review	13
Future space experiment platforms for astrobiology and astrochemistry research	13
Cellular response in three-dimensional spheroids and tissues exposed to real and simulated microgravity: a narrative review	13
Formaldehyde initiates memory and motor impairments under weightlessness condition	12
Electromagnetic levitation containerless processing of metallic materials in microgravity: rapid solidification	12
A demographic comparison of NASA astronauts and commercial spaceflight participants	12
Assessing the scientific and economic impacts of the experiments conducted onboard the International Space Station	12
The rubber hand illusion in microgravity and water immersion	12
Fluidic shaping and in-situ measurement of liquid lenses in microgravity	12
Discoveries from human stem cell research in space that are relevant to advancing cellular therapies on Earth	12
Microgravity studies of solidification patterns in model transparent alloys onboard the International Space Station	12
Terrestrial health applications of visual assessment technology and machine learning in spaceflight associated neuro-ocular syndrome	12
The impact of gravity on perceived object height	12
Reinforcement learned adversarial agent (ReLAA) for active fault detection and prediction in space habitats	11
Calycosin prevents bone loss induced by hindlimb unloading	11
Magnetic phase separation in microgravity	11
Soil conditioning for enhancing plant growth using biochar and hydrochar under microgravity	11
Human skeletal muscle tissue chip autonomous payload reveals changes in fiber type and metabolic gene expression due to spaceflight	11
Influence of the spaceflight environment on macrophage lineages	11
Efficient long-term cryopreservation of Arthrospira platensis NIES-39 and adaptation for the Space Algae-2 spaceflight experiment	11
Simulated deep space exposure on seeds utilizing the MISSE flight facility	11
Development and flight-testing of modular autonomous cultivation systems for biological plastics upcycling aboard the ISS	11
The effect of long-term spaceflight on drug potency and the risk of medication failure	11
Microbial applications for sustainable space exploration beyond low Earth orbit	11
Critical investments in bioregenerative life support systems for bioastronautics and sustainable lunar exploration	11
Nitrogen flow boiling and chilldown experiments in microgravity using pulse flow and low-thermally conductive coatings	11