ACS Infectious Diseases

Article	Citations
Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease	220
Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients	187
Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin	123
Anti-SARS-CoV-2 Potential of Artemisinins In Vitro	116
Recent Innovations in Bacterial Infection Detection and Treatment	113
Current and Perspective Diagnostic Techniques for COVID-19	112
Are Quaternary Ammonium Compounds, the Workhorse Disinfectants, Effective against Severe Acute Respiratory Syndrome-Coronavirus-2?	93
Comparative Analysis of Primer–Probe Sets for RT-qPCR of COVID-19 Causative Virus (SARS-CoV-2)	90
Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies	78
Small-Molecule Inhibitors of the Coronavirus Spike: ACE2 Protein–Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2	74
Synthetic Antimicrobial Polymers in Combination Therapy: Tackling Antibiotic Resistance	72
Electrochemical Diagnostics for Bacterial Infectious Diseases	72
Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-19	70
Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses	69
Human Cathelicidin Inhibits SARS-CoV-2 Infection: Killing Two Birds with One Stone	64
Prospecting Human Milk Oligosaccharides as a Defense Against Viral Infections	60
Effects of Antibiotic Treatment on Gut Microbiota and How to Overcome Its Negative Impacts on Human Health	58
The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules	57
Clinical and Laboratory Diagnosis of SARS-CoV-2, the Virus Causing COVID-19	56
The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors	55
Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease	54
Exogenous Nitric Oxide Improves Antibiotic Susceptibility in Resistant Bacteria	53
Emerging Vaccine-Breakthrough SARS-CoV-2 Variants	48
Reproducible Breath Metabolite Changes in Children with SARS-CoV-2 Infection	47
Two Years into the COVID-19 Pandemic: Lessons Learned	47

The Antibacterial Research and Development Pipeline Needs Urgent Solutions	46
Current Perspective of Antiviral Strategies against COVID-19	45
Codelivery of Sustainable Antimicrobial Agents and Platelet-Derived Growth Factor via Biodegradable Nanofibers for Repair of Diabetic Infectious Wounds	43
Prioritization of Molecular Targets for Antimalarial Drug Discovery	42
Structure–Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae	41
Mucin-Degrading Microbes Release Monosaccharides That Chemoattract Clostridioides difficile and Facilitate Colonization of the Human Intestinal Mucus Layer	41
Old Drugs for a New Virus: Repurposed Approaches for Combating COVID-19	40
Plasmodium Kinases as Potential Drug Targets for Malaria: Challenges and Opportunities	39
Therapeutic Potential of Nitazoxanide: An Appropriate Choice for Repurposing versus SARS-CoV-2?	38
Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens	38
Kanamycin Uptake into Escherichia coli Is Facilitated by OmpF and OmpC Porin Channels Located in the Outer Membrane	38
Immunogenicity and Protective Efficacy of a Highly Thermotolerant, Trimeric SARS-CoV-2 Receptor Binding Domain Derivative	36
COVID-19: Living through Another Pandemic	36
Synergistic Effects of Phage–Antibiotic Combinations against Citrobacter amalonaticus	35
Synergy by Perturbing the Gram-Negative Outer Membrane: Opening the Door for Gram-Positive Specific Antibiotics	35
HBsAg, Subviral Particles, and Their Clearance in Establishing a Functional Cure of Chronic Hepatitis B Virus Infection	34
Detection, Mapping, and Proteotyping of SARS-CoV-2 Coronavirus with High Resolution Mass Spectrometry	34
A Glance at Antimicrobial Strategies to Prevent Catheter-Associated Medical Infections	34
From Antibacterial to Antibiofilm Targeting: An Emerging Paradigm Shift in the Development of Quaternary Ammonium Compounds (QACs)	34
Structure and Mutations of SARS-CoV-2 Spike Protein: A Focused Overview	34
JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo	33
Gut Microbiota and Gynecological Cancers: A Summary of Pathogenetic Mechanisms and Future Directions	33
Heterologous Protein Expression Favors the Formation of Protein Aggregates in Persister and Viable but Nonculturable Bacteria	32
Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum	32
Nanomaterials: The New Antimicrobial Magic Bullet	32
Alternatives to Praziquantel for the Prevention and Control of Schistosomiasis	31
ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Produc	31
An Updated View of the Trypanosoma cruzi Life Cycle: Intervention Points for an Effective Treatment	31
Inhibitors of L-Type Calcium Channels Show Therapeutic Potential for Treating SARS-CoV-2 Infections by Preventing Virus Entry and Spread	30
Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain	30
Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium falciparum Infected Red Blood Cells	29
Quinoline and Quinazoline Derivatives Inhibit Viral RNA Synthesis by SARS-CoV-2 RdRp	29
Gallium(III)–Salophen as a Dual Inhibitor of Pseudomonas aeruginosa Heme Sensing and Iron Acquisition	29
High-Throughput Screening of an FDA-Approved Drug Library Identifies Inhibitors against Arenaviruses and SARS-CoV-2	28
Targeting Crucial Host Factors of SARS-CoV-2	28
Vancomycin C-Terminus Guanidine Modifications and Further Insights into an Added Mechanism of Action Imparted by a Peripheral Structural Modification	27
To Push or To Pull? In a Post-COVID World, Supporting and Incentivizing Antimicrobial Drug Development Must Become a Governmental Priority	27
Antibiotics Special Issue: Challenges and Opportunities in Antibiotic Discovery and Development	26
Periplasmic Targets for the Development of Effective Antimicrobials against Gram-Negative Bacteria	26
Compound Uptake into E. coli Can Be Facilitated by N-Alkyl Guanidiniums and Pyridiniums	26
Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin	26
Photodynamic Inactivation of ESKAPE Group Bacterial Pathogens in Planktonic and Biofilm Cultures Using Metallated Porphyrin-Doped Conjugated Polymer Nanoparticles	26
Recent Advances in the Development of Semisynthetic Glycopeptide Antibiotics: 2014–2022	26
Local and Sustained Delivery of Rifampicin from a Bioactive Ceramic Carrier Treats Bone Infection in Rat Tibia	26
Synthesis and Biological Activities of Oxazolidinone Pleuromutilin Derivatives as a Potent Anti-MRSA Agent	25
Helicity Modulation Improves the Selectivity of Antimicrobial Peptoids	25
Antibiotic Potentiation in Multidrug-Resistant Gram-Negative Pathogenic Bacteria by a Synthetic Peptidomimetic	25
Short and Robust Anti-Infective Lipopeptides Engineered Based on the Minimal Antimicrobial Peptide KR12 of Human LL-37	25
Dilipid Ultrashort Tetrabasic Peptidomimetics Potentiate Novobiocin and Rifampicin Against Multidrug-Resistant Gram-Negative Bacteria	25
Gallium Porphyrin and Gallium Nitrate Synergistically Inhibit Mycobacterial Species by Targeting Different Aspects of Iron/Heme Metabolism	24

Targeting Polyamines Inhibits Coronavirus Infection by Reducing Cellular Attachment and Entry	24
Discovery, Synthesis, and Biological Evaluation of Dunnianol-Based Mannich Bases against Methicillin-Resistant Staphylococcus aureus (MRSA)	24
Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa	23
Recent Insights into Emerging Coronavirus: SARS-CoV-2	23
A Microbe-Derived Efflux Pump Inhibitor of the Resistance-Nodulation-Cell Division Protein Restores Antibiotic Susceptibility in Escherichia coli and Pseudomonas aeruginosa	23
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria	23
Emerging Roles of Glycopeptide Antibiotics: Moving beyond Gram-Positive Bacteria	23
Pseudomonas aeruginosa Biofilm Eradication via Nitric Oxide-Releasing Cyclodextrins	23
Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses	22
Modeling Enteropathy or Diarrhea with the Top Bacterial and Protozoal Pathogens: Differential Determinants of Outcomes	22
A Highly Potent SARS-CoV-2 Blocking Lectin Protein	22
Membrane-Permeable Antibacterial Enzyme against Multidrug-Resistant Acinetobacter baumannii	22
Ultradeformable Lipid Vesicles Localize Amphotericin B in the Dermis for the Treatment of Infectious Skin Diseases	22
Diclazuril Inhibits Biofilm Formation and Hemolysis of Staphylococcus aureus	21
Polyethylenimine: An Intranasal Adjuvant for Liposomal Peptide-Based Subunit Vaccine against Group A Streptococcus	21
Screening an Established Natural Product Library Identifies Secondary Metabolites That Potentiate Conventional Antibiotics	21
Chagas Disease: Current View of an Ancient and Global Chemotherapy Challenge	21
Development of Advanced Chimeric Endolysin to Control Multidrug-Resistant Staphylococcus aureus through Domain Shuffling	21
Structure–Activity Relationship Exploration of 3′-Deoxy-7-deazapurine Nucleoside Analogues as Anti-Trypanosoma brucei Agents	21
Cationic Antimicrobial Peptides Are Leading the Way to Combat Oropathogenic Infections	21
Antibiotic Therapy and the Gut Microbiome: Investigating the Effect of Delivery Route on Gut Pathogens	21
Ceftazidime–Avibactam Resistance Mutations V240G, D179Y, and D179Y/T243M in KPC-3 β-Lactamase Do Not Alter Cefpodoxime–ETX1317 Susceptibility	21
Clinically Relevant Bacterial Outer Membrane Models for Antibiotic Screening Applications	21
Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2	21
Altered Gut Microbiome under Antiretroviral Therapy: Impact of Efavirenz and Zidovudine	20
A Marine Antibiotic Kills Multidrug-Resistant Bacteria without Detectable High-Level Resistance	20
How to Stimulate and Facilitate Early Stage Antibiotic Discovery	20
Synthesis of Fusidic Acid Derivatives Yields a Potent Antibiotic with an Improved Resistance Profile	20
Inhibition of Human Coronaviruses by Antimalarial Peroxides	20
Expanding Bromodomain Targeting into Neglected Parasitic Diseases	20
Imaging of Actively Proliferating Bacterial Infections by Targeting the Bacterial Metabolic Footprint with d-[5-11C]-Glutamine	20
Effective Strategy Targeting Polymyxin-Resistant Gram-Negative Pathogens: Polymyxin B in Combination with the Selective Serotonin Reuptake Inhibitor Sertraline	20
Overcoming Planktonic and Intracellular Staphylococcus aureus-Associated Infection with a Cell-Penetrating Peptide-Conjugated Antimicrobial Peptide	20
The SARS-CoV-2 SSHHPS Recognized by the Papain-like Protease	19
SaccuFlow: A High-Throughput Analysis Platform to Investigate Bacterial Cell Wall Interactions	19
Small Molecule Inhibitors of the Bacterioferritin (BfrB)–Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells	19
Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic Pathogen Klebsiella oxytoca	19
A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules	19
Protective Liquid Crystal Nanoparticles for Targeted Delivery of PslG: A Biofilm Dispersing Enzyme	19
Quaternary Phosphonium Compounds: An Examination of Non-Nitrogenous Cationic Amphiphiles That Evade Disinfectant Resistance	18
Mechanistic Duality of Bacterial Efflux Substrates and Inhibitors: Example of Simple Substituted Cinnamoyl and Naphthyl Amides	18
Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy	18
The Global Antibiotic Research and Development Partnership (GARDP) Not-for-Profit Model of Antibiotic Development	18
Structural Basis of Metallo-β-lactamase Inhibition byN-Sulfamoylpyrrole-2-carboxylates	18
Benzimidazole Derivatives Are Potent against Multiple Life Cycle Stages of Plasmodium falciparum Malaria Parasites	18
Structure–Interaction Relationship of Polymyxins with the Membrane of Human Kidney Proximal Tubular Cells	18
Investigating β-Lactam Drug Targets in Mycobacterium tuberculosis Using Chemical Probes	18
Exploitation of a Klebsiella Bacteriophage Receptor-Binding Protein as a Superior Biorecognition Molecule	18
Outer Membranes of Polymyxin-Resistant Acinetobacter baumannii with Phosphoethanolamine-Modified Lipid A and Lipopolysaccharide Loss Display Different Atomic-Scale Interactions with Polymyxins	18
A Salmochelin S4-Inspired Ciprofloxacin Trojan Horse Conjugate	18
Mechanistic Basis of OXA-48-like β-Lactamases’ Hydrolysis of Carbapenems	18
Alterations of the Treatment-Naive Gut Microbiome in Newly Diagnosed Hepatitis C Virus Infection	18
Recombinant Human Secretory IgA Induces Salmonella Typhimurium Agglutination and Limits Bacterial Invasion into Gut-Associated Lymphoid Tissues	18
Pharmacological Characterization of the Mechanism of Action of R523062, a Promising Antiviral for Enterovirus D68	18
Small Molecule Sensors Targeting the Bacterial Cell Wall	18
Overcoming Acquired and Native Macrolide Resistance with Bicarbonate	18
A Clerodane Diterpene from Callicarpa americana Resensitizes Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics	17
Combining Colistin and Fluconazole Synergistically Increases Fungal Membrane Permeability and Antifungal Cidality	17
Therapeutic and Prophylactic Effect of the Experimental Bacteriophage Treatment to Control Diarrhea Caused by E. coli in Newborn Calves	17
Analysis of Antimicrobial and Antibiofilm Activity of Human Milk Lactoferrin Compared to Bovine Lactoferrin against Multidrug Resistant and Susceptible Acinetobacter baumannii Clinical Isolates	17
Ag@ZnO Nanoparticles Induce Antimicrobial Peptides and Promote Migration and Antibacterial Activity of Keratinocytes	17
Inhibition of Influenza Virus Polymerase by Interfering with Its Protein–Protein Interactions	17
Conjugation to Enterobactin and Salmochelin S4 Enhances the Antimicrobial Activity and Selectivity of β-Lactam Antibiotics against Nontyphoidal Salmonella	17
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni	17
Selective Permeabilization of Gram-Negative Bacterial Membranes Using Multivalent Peptide Constructs for Antibiotic Sensitization	17
Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern	17
Metabolic Glycan Labeling-Based Screen to Identify Bacterial Glycosylation Genes	17
Early Returns on Small Molecule Therapeutics for SARS-CoV-2	16
Discovery of Amphamide, a Drug Candidate for the Second Generation of Polyene Antibiotics	16
Synthesis, Structure–Activity Relationship, and Mechanistic Studies of Aminoquinazolinones Displaying Antimycobacterial Activity	16
Spatially Targeted Proteomics of the Host–Pathogen Interface during Staphylococcal Abscess Formation	16
Aptamers for Viral Detection and Inhibition	16
2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode	16
An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization	16
Impact of Glycan Linkage to Staphylococcus aureus Wall Teichoic Acid on Langerin Recognition and Langerhans Cell Activation	16
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum	16
MicroRNA-18b-5p Downregulation Favors Mycobacterium tuberculosis Clearance in Macrophages via HIF-1α by Promoting an Inflammatory Response	16
Feleucin-K3 Analogue with an α-(4-Pentenyl)-Ala Substitution at the Key Site Has More Potent Antimicrobial and Antibiofilm Activities in Vitro and in Vivo	16
Pyochelin Biosynthetic Metabolites Bind Iron and Promote Growth in Pseudomonads Demonstrating Siderophore-like Activity	16
Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase	16

Vancomyxins: Vancomycin-Polymyxin Nonapeptide Conjugates That Retain Anti-Gram-Positive Activity with Enhanced Potency against Gram-Negative Strains	16
Induction of Endogenous Antibody Recruitment to the Surface of the Pathogen Enterococcus faecium	16
Cowpea Mosaic Virus Nanoparticle Vaccine Candidates Displaying Peptide Epitopes Can Neutralize the Severe Acute Respiratory Syndrome Coronavirus	16
Post-translational Succinylation of Mycobacterium tuberculosis Enoyl-CoA Hydratase EchA19 Slows Catalytic Hydration of Cholesterol Catabolite 3-Oxo-chol-4,22-diene-24-oyl-CoA	16
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease Outbreaks	15
Repurposing Nonantifungal Approved Drugs for Synergistic Targeting of Fungal Pathogens	15
Plasmodium falciparum Acetyl-CoA Synthetase Is Essential for Parasite Intraerythrocytic Development and Chromatin Modification	15
Exotoxin-Targeted Drug Modalities as Antibiotic Alternatives	15
Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions	15
Design Guidelines for Cationic Pillar[n]arenes that Prevent Biofilm Formation by Gram-Positive Pathogens	15
Type II Antitoxin HigA Is a Key Virulence Regulator in Pseudomonas aeruginosa	15
Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors	15
PEP27-2, a Potent Antimicrobial Cell-Penetrating Peptide, Reduces Skin Abscess Formation during Staphylococcus aureus Infections in Mouse When Used in Combination with Antibiotics	15
Development of Antibiotics That Dysregulate the Neisserial ClpP Protease	15
Synthetic Mimics of Native Siderophores Disrupt Iron Trafficking in Acinetobacter baumannii	15
Hyper-Synergistic Antifungal Activity of Rapamycin and Peptide-Like Compounds against Candida albicans Orthogonally via Tor1 Kinase	15
Virulence and Adhesion of the Treponema pallidum Nichols Strain Simultaneously Decrease in a Continuous-Infection New Zealand White Rabbit Model	15
Positron Emission Tomography Imaging of Staphylococcus aureus Infection Using a Nitro-Prodrug Analogue of 2-[18F]F-p-Aminobenzoic Acid	15
Toward a Stable and Potent Coenzyme A-Targeting Antiplasmodial Agent: Structure–Activity Relationship Studies of N-Phenethyl-α-methyl-pantothenamide	15
A Semisynthetic Kanglemycin Shows In Vivo Efficacy against High-Burden Rifampicin Resistant Pathogens	15
Progress toward the Development of Glycan-Based Vaccines against Campylobacteriosis	15
Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma cruzi	15
Virion-Associated Polyamines Transmit with Bunyaviruses to Maintain Infectivity and Promote Entry	14
Preclinical Development of Pentamidine Analogs Identifies a Potent and Nontoxic Antibiotic Adjuvant	14
Discovery of Prenyltransferase Inhibitors with In Vitro and In Vivo Antibacterial Activity	14
Development in the Concept of Bacterial Polysaccharide Repeating Unit-Based Antibacterial Conjugate Vaccines	14
Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology	14
Targeting a Potential G-Quadruplex Forming Sequence Found in the West Nile Virus Genome by Complementary Gamma-Peptide Nucleic Acid Oligomers	14
Sustained Release of a Streptococcus pneumoniae Endolysin from Liposomes for Potential Otitis Media Treatment	14
Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis	14
Investigational Studies on a Hit Compound Cyclopropane–Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant	14
Polysaccharide Succinylation Enhances the Intracellular Survival of Mycobacterium abscessus	14
Structural Basis for the Regulation of Biofilm Formation and Iron Uptake in A. baumannii by the Blue-Light-Using Photoreceptor, BlsA	14
Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase	14
Pyronaridine Protects against SARS-CoV-2 Infection in Mouse	14
No-Observed-Effect Level of Silver Phosphate in Carbonate Apatite Artificial Bone on Initial Bone Regeneration	14
Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease	14
Structural Basis for Inhibitor Potency and Selectivity of Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors	14
Salicylanilides Reduce SARS-CoV-2 Replication and Suppress Induction of Inflammatory Cytokines in a Rodent Model	14
Mycobacterium Lipids Modulate Host Cell Membrane Mechanics, Lipid Diffusivity, and Cytoskeleton in a Virulence-Selective Manner	14
Real-Time Single-Cell Imaging Reveals Accelerating Lipid Peroxyl Radical Formation in Escherichia coli Triggered by a Fluoroquinolone Antibiotic	14
Antimicrobial Susceptibility Testing of Antimicrobial Peptides Requires New and Standardized Testing Structures	14
Synthetic Oligomers Mimicking Capsular Polysaccharide Diheteroglycan are Potential Vaccine Candidates against Encapsulated Enterococcal Infections	14
Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition	14
Antibacterial Photodynamic Therapy in the Near-Infrared Region with a Targeting Antimicrobial Peptide Connected to a π-Extended Porphyrin	14
Resveratrol Attenuates Meningitic Escherichia coli-Mediated Blood–Brain Barrier Disruption	14
Pharmacokinetic/Pharmacodynamic Determination and Preclinical Pharmacokinetics of the β-Lactamase Inhibitor ETX1317 and Its Orally Available Prodrug ETX0282	14
Synergy of the Polymyxin-Chloramphenicol Combination against New Delhi Metallo-β-Lactamase-Producing Klebsiella pneumoniae Is Predominately Driven by Chloramphenicol	14
O-Methylation of the Glycopeptidolipid Acyl Chain Defines Surface Hydrophobicity of Mycobacterium abscessus and Macrophage Invasion	13
From Magic Bullet to Magic Bomb: Reductive Bioactivation of Antiparasitic Agents	13
Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and In Vivo Studies	13
Structure, In Vivo Detection, and Antibacterial Activity of Metabolites of SQ109, an Anti-Infective Drug Candidate	13
Antibiofilm Activity of Human Milk Oligosaccharides against Multidrug Resistant and Susceptible Isolates of Acinetobacter baumannii	13
Combining Cell Envelope Stress Reporter Assays in a Screening Approach to Identify BAM Complex Inhibitors	13
Modular Synthetic Routes to Fluorine-Containing Halogenated Phenazine and Acridine Agents That Induce Rapid Iron Starvation in Methicillin-Resistant Staphylococcus aureus Biofilms	13
Intrinsic Antimicrobial Peptide Facilitates a New Broad-Spectrum Lysin LysP53 to Kill Acinetobacter baumannii In Vitro and in a Mouse Burn Infection Model	13
Comprehensive Lipidomic and Metabolomic Analysis for Studying Metabolic Changes in Lung Tissue Induced by a Vaccine against Respiratory Syncytial Virus	13
Influence of Lipophilicity on the Antibacterial Activity of Polymyxin Derivatives and on Their Ability to Act as Potentiators of Rifampicin	13
Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in Mycobacterium tuberculosis	13
Herbicides That Target Acetohydroxyacid Synthase Are Potent Inhibitors of the Growth of Drug-Resistant Candida auris	13
Antisense Peptide Nucleic Acid–Diaminobutanoic Acid Dendron Conjugates with SbmA-Independent Antimicrobial Activity against Gram-Negative Bacteria	13
Group B Streptococcus cpsE Is Required for Serotype V Capsule Production and Aids in Biofilm Formation and Ascending Infection of the Reproductive Tract during Pregnancy	13
Cell Surface Remodeling of Mycobacterium abscessus under Cystic Fibrosis Airway Growth Conditions	13
Design, Synthesis, and Biological Evaluation of Light-Activated Antibiotics	13
Evaluation of Peptide-Based Probes toward In Vivo Diagnostic Imaging of Bacterial Biofilm-Associated Infections	13
Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity	13
HIV-1 Integrase Inhibitors with Modifications That Affect Their Potencies against Drug Resistant Integrase Mutants	13
Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors	13
Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus	13
Virus-like Particle Display of Vibrio cholerae O-Specific Polysaccharide as a Potential Vaccine against Cholera	13
1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of β-Lactamase Inhibitors against Acinetobacter baumannii Cephalosporinase	13
Drug-Repurposing Screening Identified Tropifexor as a SARS-CoV-2 Papain-like Protease Inhibitor	13
Discovery of Piperidol Derivatives for Combinational Treatment of Azole-Resistant Candidiasis	13
Design of a Sea Snake Antimicrobial Peptide Derivative with Therapeutic Potential against Drug-Resistant Bacterial Infection	13
Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections In Vivo	13
Antifungal Susceptibility Testing of Aspergillus niger on Silicon Microwells by Intensity-Based Reflectometric Interference Spectroscopy	12
Vitamin D and Streptococci: The Interface of Nutrition, Host Immune Response, and Antimicrobial Activity in Response to Infection	12
Intrinsically Disordered Proteins: Perspective on COVID-19 Infection and Drug Discovery	12
Peptide Methionine Sulfoxide Reductase from Haemophilus influenzae Is Required for Protection against HOCl and Affects the Host Response to Infection	12
High-Throughput Immunochemical Method to Assess the 2-Heptyl-4-quinolone Quorum Sensing Molecule as a Potential Biomarker of Pseudomonas aeruginosa Infections	12
Using a Fragment-Based Approach to Identify Alternative Chemical Scaffolds Targeting Dihydrofolate Reductase from Mycobacterium tuberculosis	12
Conjugation of Aztreonam, a Synthetic Monocyclic β-Lactam Antibiotic, to a Siderophore Mimetic Significantly Expands Activity Against Gram-Negative Bacteria	12
Gallium Porphyrin and Gallium Nitrate Reduce the High Vancomycin Tolerance of MRSA Biofilms by Promoting Extracellular DNA-Dependent Biofilm Dispersion	12
A Noncytotoxic Temporin L Analogue with In Vivo Antibacterial and Antiendotoxin Activities and a Nonmembrane-Lytic Mode of Action	12
Uptake Mechanisms and Regulatory Responses to MECAM- and DOTAM-Based Artificial Siderophores and Their Antibiotic Conjugates in Pseudomonas aeruginosa	12
Structure–Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs	12
Development of Antimicrobial Peptide–Antibiotic Conjugates to Improve the Outer Membrane Permeability of Antibiotics Against Gram-Negative Bacteria	12
Polymyxin Stereochemistry and Its Role in Antibacterial Activity and Outer Membrane Disruption	12
Pyridinium Modified Anthracenes and Their Endoperoxides Provide a Tunable Scaffold with Activity against Gram-Positive and Gram-Negative Bacteria	12
Spiro-β-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium	12
Random Peptide Mixtures as Safe and Effective Antimicrobials against Pseudomonas aeruginosa and MRSA in Mouse Models of Bacteremia and Pneumonia	12
The Acinetobacter baumannii Autotransporter Adhesin Ata Recognizes Host Glycans as High-Affinity Receptors	12
Expanding the Activity Profile of Pyrido[1,2-a]benzimidazoles: Synthesis and Evaluation of Novel N1-1-Phenylethanamine Derivatives against Schistosoma mansoni	12
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis	12
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors	12