OOIR: Observatory of International Research

Papers

(The H4-Index of Science Advances is 134. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Discovery of an autoinhibited conformation in mesotrypsin reveals a strategy for selective serine protease inhibition	1563
Anabolic indices of matrix proteins identify regenerative small RNA intrinsic to human cartilage	576
Bone-inspired stress-gaining elastomer enabled by dynamic molecular locking	444
Artificial biomarker-based feedback-regulated personalized and precise thrombolysis with lower hemorrhagic risk	401
Upward propagation of gigantic jets revealed by 3D radio and optical mapping	357
2D material exciton-polariton transport on 2D photonic crystals	307
Real-time antiproton annihilation vertexing with submicrometer resolution	298
Distinct armchair and zigzag charge transport through single polycyclic aromatics	297
Particle-armored liquid robots	269
Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function	269
Cold exposure stimulates cross-tissue metabolic rewiring to fuel glucose-dependent thermogenesis in brown adipose tissue	267
Multiplexed mapping of the interactome of GPCRs with receptor activity–modifying proteins	263
Mismatched ligand density enables ordered assembly of mixed-dimensional, cross-species materials	262
Chaperone-mediated heterotypic phase separation regulates liquid-to-solid phase transitions of tau into amyloid fibrils	258
Spatially resolved single-cell atlas of ascidian endostyle provides insight into the origin of vertebrate pharyngeal organs	255
Enhancer dynamics: Unraveling the mechanism of transcriptional bursting	253
Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy	251
6mA-Sniper: Quantifying 6mA sites in eukaryotes at single-nucleotide resolution	244
GPCR-mediated calcium and cAMP signaling determines psychosocial stress susceptibility and resiliency	243
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress	243
Predicting three-component reaction outcomes from ~40,000 miniaturized reactant combinations	241
Signatures of speech and song: “Universal” links despite cultural diversity	240
Complementary corticostriatal circuits orchestrate action repetition and switching	239
Enhanced Rap1 small GTPase activity in the ventral hippocampus drives stress-induced anxiety	235
Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes	233

Blind identification of the spinal cord output in humans with high-density electrode arrays implanted in muscles	231
The molecular mechanism of sialic acid transport mediated by Sialin	228
Oral iron sulfide prevents acute alcohol intoxication by initiating the endogenous multienzymatic antioxidant defense system	227
Biological export production controls upper ocean calcium carbonate dissolution and CO ₂ buffer capacity	224
Editor’s note and erratum for the Research Article: “Unemployment and underemployment are causes of suicide”	224
Fast cortical dynamics encode tactile grating orientation during active touch	223
Palimpsest memories stored in memristive synapses	219
Gating of hair cell Ca ²⁺ channels governs the activity of cochlear neurons	218
Saturn’s F ring is intermittently shepherded by Prometheus	218
Chromobacterium biopesticide overcomes insecticide resistance in malaria vector mosquitoes	217
Erratum for the Research Article: “SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8 ⁺ T cell cytotoxic function” by X. Liu	216
Developmentally programmed histone H3 expression regulates cellular plasticity at the parental-to-early embryo transition	212
CMOS-compatible electro-optical SRAM cavity device based on negative differential resistance	212
Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration	212
Targeting TRPC channels for control of arthritis-induced bone erosion	211
MiniXL: An open-source, large field-of-view epifluorescence miniscope enabling single-cell resolution and multi-region imaging in mice	209
An annually resolved 5700-year storm archive reveals drivers of Caribbean cyclone frequency	208
Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility	207
RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS	205
Dephosphorylation and ion binding in prokaryotic calcium transport	205
Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies	203
Ag-doped non–imperfection-enabled uniform memristive neuromorphic device based on van der Waals indium phosphorus sulfide	202
Tree-ring stable isotopes from the European Alps reveal long-term summer drying over the Holocene	202
Pathways to concealed gun carrying	199
Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity	192
Long noncoding RNA DREAMer bridges the DREAM complex and E2f1 to regulate endoreplication in Drosophila	191
Optimizing the timing of an end-of-outbreak declaration: Ebola virus disease in the Democratic Republic of the Congo	190
Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions	189
Inflammatory responses to acute carbon monoxide poisoning and the role of plasma gelsolin	189
Cpeb1 remodels cell type–specific translational program to promote fear extinction	189
Microsecond dynamics control the HIV-1 Envelope conformation	188
Erratum for the Research Article: “Oscillation of type IV pili regulated by the circadian clock in cyanobacterium Synechococcus elongatus PCC7942” by Zhang <	188
Depolarization block in olfactory sensory neurons expands the dimensionality of odor encoding	186
Considering intentional stratospheric dehydration for climate benefits	183
Erratum for the Research Article: “TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma” by Sun et al .	183
Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics	180
Diversification of the ruminant skull along an evolutionary line of least resistance	180
Quantized critical supercurrent in SrTiO ₃ -based quantum point contacts	180
Broadband photodetection of intense lasers via exciton-enhanced high-order multiphoton-absorption optoelectronics in 2D hybrid perovskite	180
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization	178
Real-time observation of non-equilibrium phonon-electron energy and angular momentum flow in laser-heated nickel	177
Electrostatic nano-mask patterned 180° domain walls in a ferroelectric film	176
A molecular switch controls assembly of bacterial focal adhesions	175
The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation	174
The super elongation complex drives transcriptional addiction in MYCN -amplified neuroblastoma	174
Driving forces of Antarctic krill abundance	173
The cohesin stabilizer Sororin drives G ₂ -M transition and spindle assembly in mammalian oocytes	172
Small effect of partial melt on electrical anomalies in the asthenosphere	172
Rise in broadly cross-reactive adaptive immunity against human β-coronaviruses in MERS-recovered patients during the COVID-19 pandemic	171
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex	170

Observation of dynamic nuclear polarization echoes	170
Compressing slippery surface-assembled amphiphiles for tunable haptic energy harvesters	170
Overexpression of the scopoletin biosynthetic pathway enhances lignocellulosic biomass processing	170
Erratum for the Research Article: “Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell”	167
Buffering of genetic dominance by allele-specific protein complex assembly	167
Genome wide nucleosome landscape shapes 3D chromatin organization	166
How genomic insights into the evolutionary history of clouded leopards inform their conservation	164
Episodic reef growth in the Last Interglacial driven by competing influence of polar ice sheets to sea level rise	161
A two-stage mantle plume-sagduction origin of Archean continental crust revealed by water and oxygen isotopes of TTGs	160
Ancient genomes reveal Avar-Hungarian transformations in the 9th-10th centuries CE Carpathian Basin	160
A conserved molecular template underlies color pattern diversity in estrildid finches	159
A computational mechanism of cue-stimulus integration for pain in the brain	159
Analysis of sloppiness in model simulations: Unveiling parameter uncertainty when mathematical models are fitted to data	159
Distributed interfacing by nanoscale photodiodes enables single-neuron light activation and sensory enhancement in 3D spinal explants	157
Cellular stiffness sensing through talin 1 in tissue mechanical homeostasis	157
Inherent tendency of Synechococcus and heterotrophic bacteria for mutualism on long-term coexistence despite environmental interference	156
VARP binds SNX27 to promote endosomal supercomplex formation on membranes	156
Elucidating the characteristics and clonal evolutionary trajectory of influenza neuraminidase broadly reactive B cell	156
Tailoring sub-3.3 Å ultramicropores in advanced carbon molecular sieve membranes for blue hydrogen production	153
Emergence and reconfiguration of modular structure for artificial neural networks during continual familiarity detection	153
Sensory-motor circuit is a therapeutic target for dystonia musculorum mice, a model of hereditary sensory and autonomic neuropathy 6	151
Structures of neurokinin 1 receptor in complex with G _q and G _s proteins reveal substance P binding mode and unique activation fea	150
Non-adapted bacterial infection suppresses plant reproduction	149
A radio pulsar phase from SGR J1935+2154 provides clues to the magnetar FRB mechanism	148
The synovial environment steers cartilage deterioration and regeneration	148
Engineering edgeless human skin with enhanced biomechanical properties	148
Phylogenetic tracing of midbrain-specific regulatory sequences suggests single origin of eubilaterian brains	147
Time-resolving state-specific molecular dissociation with XUV broadband absorption spectroscopy	146
The extinct shark Otodus megalodon was a transoceanic superpredator: Inferences from 3D modeling	146
Convergent consequences of parthenogenesis on stick insect genomes	145
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 ⁺ T cell responses	145
Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions	145
Diamond-based microwave quantum amplifier	144
Abiotic molecular oxygen production—Ionic pathway from sulfur dioxide	144
Motion Hologram: Jointly optimized hologram generation and motion planning for photorealistic 3D displays via reinforcement learning	143
Sensing spin wave excitations by spin defects in few-layer-thick hexagonal boron nitride	142
In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI	142
Hidden white and black feather layers enhance plumage coloration in tanagers and other songbirds	141
Donor HLA-DQ genetic and functional divergence affect the control of BK polyoma virus infection after kidney transplantation	141
Low-dose metformin requires brain Rap1 for its antidiabetic action	141
Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization	140
27-Hydroxycholesterol acts on estrogen receptor α expressed by POMC neurons in the arcuate nucleus to modulate feeding behavior	140
DNA repair during nonreductional meiosis in the asexual rotifer Adineta vaga	140
DNA damage response pathway regulates Nrf2 in response to oxidative stress	140
Global health risks lurking in livestock resistome	140
Role of HAUS7 as a DOCK3 binding partner in facilitating axon regeneration	140
Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk	139
Multiplexed CRISPR-Cas9 mutagenesis of rice PSBS1 noncoding sequences for transgene-free overexpression	139
Quantifying structural relationships of metal-binding sites suggests origins of biological electron transfer	139
Deep and dynamic metabolic and structural imaging in living tissues	139
Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells	137
Shear shock waves mediate haptic holography via focused ultrasound	136
Ultrafast tomograms in a flash	136
Underwater metamaterial absorber with impedance-matched composite	136
Identification of the Wnt signal peptide that directs secretion on extracellular vesicles	136
Fluid dynamical pathways of airborne transmission while waiting in a line	136
Diurnal urban rainfall anomalies across different landscapes	136
Smart ultra-long-lasting sequentially triggerable and artfully implantable nozzle system for on-demand drug delivery for chronotherapy	135
Miniature color camera via flat hybrid meta-optics	135
Comediation of voltage gating and ion charge in MXene membrane for controllable and selective monovalent cation separation	134
Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis	134
Fungal-fungal cocultivation leads to widespread secondary metabolite alteration requiring the partial loss-of-function VeA1 protein	134
Cerebrospinal fluid flow extends to peripheral nerves further unifying the nervous system	134
Direct observations of cross-scale wave-particle energy transfer in space plasmas	134
An artificial sodium-selective subnanochannel	134