Science Advances

Papers
(The H4-Index of Science Advances is 133. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Discovery of an autoinhibited conformation in mesotrypsin reveals a strategy for selective serine protease inhibition1470
Anabolic indices of matrix proteins identify regenerative small RNA intrinsic to human cartilage546
Global health risks lurking in livestock resistome427
DNA damage response pathway regulates Nrf2 in response to oxidative stress421
Role of HAUS7 as a DOCK3 binding partner in facilitating axon regeneration375
Hidden white and black feather layers enhance plumage coloration in tanagers and other songbirds349
Bone-inspired stress-gaining elastomer enabled by dynamic molecular locking296
Diving into the vertical dimension of elasmobranch movement ecology289
Artificial biomarker-based feedback-regulated personalized and precise thrombolysis with lower hemorrhagic risk278
Upward propagation of gigantic jets revealed by 3D radio and optical mapping266
DNA repair during nonreductional meiosis in the asexual rotifer Adineta vaga262
Focusing of in-plane hyperbolic polaritons in van der Waals crystals with tailored infrared nanoantennas260
2D material exciton-polariton transport on 2D photonic crystals259
Distinct armchair and zigzag charge transport through single polycyclic aromatics257
Real-time antiproton annihilation vertexing with submicrometer resolution257
Sensing spin wave excitations by spin defects in few-layer-thick hexagonal boron nitride250
Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function246
Particle-armored liquid robots245
Cold exposure stimulates cross-tissue metabolic rewiring to fuel glucose-dependent thermogenesis in brown adipose tissue239
Multiplexed mapping of the interactome of GPCRs with receptor activity–modifying proteins239
Uncertainties too large to predict tipping times of major Earth system components from historical data237
Mismatched ligand density enables ordered assembly of mixed-dimensional, cross-species materials234
Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ231
Deep and dynamic metabolic and structural imaging in living tissues230
Chaperone-mediated heterotypic phase separation regulates liquid-to-solid phase transitions of tau into amyloid fibrils229
A printed luminescent flier inspired by plant seeds for eco-friendly physical sensing229
Spatially resolved single-cell atlas of ascidian endostyle provides insight into the origin of vertebrate pharyngeal organs227
GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury222
Bound chiral magnonic polariton states for ideal microwave isolation222
Laws about bodily damage originate from shared intuitions about the value of body parts219
Abiotic molecular oxygen production—Ionic pathway from sulfur dioxide217
Oxygen isotopes of anhydrous primary minerals show kinship between asteroid Ryugu and comet 81P/Wild2213
Enhancer dynamics: Unraveling the mechanism of transcriptional bursting211
High coherence and low cross-talk in a tileable 3D integrated superconducting circuit architecture211
Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy211
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress210
6mA-Sniper: Quantifying 6mA sites in eukaryotes at single-nucleotide resolution210
GPCR-mediated calcium and cAMP signaling determines psychosocial stress susceptibility and resiliency209
Predicting three-component reaction outcomes from ~40,000 miniaturized reactant combinations206
Diamond-based microwave quantum amplifier205
Complementary corticostriatal circuits orchestrate action repetition and switching204
Signatures of speech and song: “Universal” links despite cultural diversity204
Enhanced Rap1 small GTPase activity in the ventral hippocampus drives stress-induced anxiety203
Structure and dynamics determine G protein coupling specificity at a class A GPCR201
In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI200
Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes200
Blind identification of the spinal cord output in humans with high-density electrode arrays implanted in muscles199
A radio pulsar phase from SGR J1935+2154 provides clues to the magnetar FRB mechanism199
The molecular mechanism of sialic acid transport mediated by Sialin196
Fungal-fungal cocultivation leads to widespread secondary metabolite alteration requiring the partial loss-of-function VeA1 protein195
If you rise, I fall: Equality is prevented by the misperception that it harms advantaged groups195
Optical control of 4 f orbital state in rare-earth metals192
Attentional guidance through object associations in visual cortex186
Oral iron sulfide prevents acute alcohol intoxication by initiating the endogenous multienzymatic antioxidant defense system186
Biological export production controls upper ocean calcium carbonate dissolution and CO 2 buffer capacity184
Editor’s note and erratum for the Research Article: “Unemployment and underemployment are causes of suicide”183
The extinct shark Otodus megalodon was a transoceanic superpredator: Inferences from 3D modeling182
N -Heterocyclic carbene catalytic 1,2-boron migrative acylation accelerated by photocatalysis182
Fast cortical dynamics encode tactile grating orientation during active touch182
Quantifying structural relationships of metal-binding sites suggests origins of biological electron transfer182
Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses181
Truncated jarid2 and kdm6b transcripts are associated with temperature-induced sex reversal during development in a dragon lizard181
Palimpsest memories stored in memristive synapses179
Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis178
Saturn’s F ring is intermittently shepherded by Prometheus177
Gating of hair cell Ca 2+ channels governs the activity of cochlear neurons176
Modularized microrobot with lock-and-detachable modules for targeted cell delivery in bile duct175
Chromobacterium biopesticide overcomes insecticide resistance in malaria vector mosquitoes175
Engineering is pregnant with possibilities174
Hibiscus bullseyes reveal mechanisms controlling petal pattern proportions that influence plant-pollinator interactions174
The genomic landscape of familial glioma173
Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5170
Miniature battery-free epidural cortical stimulators169
Metasurface-based realization of photonic time crystals169
Erratum for the Research Article: “SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8 + T cell cytotoxic function” by X. Liu 166
Smart ultra-long-lasting sequentially triggerable and artfully implantable nozzle system for on-demand drug delivery for chronotherapy166
Developmentally programmed histone H3 expression regulates cellular plasticity at the parental-to-early embryo transition166
Separation and recycling of hydrofluorocarbon refrigerant mixtures with fluoropolymer-coated hollow fiber membranes166
Molybdate uptake interplay with ROS tolerance modulates bacterial pathogenesis164
Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration164
Predicting master transcription factors from pan-cancer expression data161
Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase161
CMOS-compatible electro-optical SRAM cavity device based on negative differential resistance160
Memristive floating-point Fourier neural operator network for efficient scientific modeling160
Targeting TRPC channels for control of arthritis-induced bone erosion160
MiniXL: An open-source, large field-of-view epifluorescence miniscope enabling single-cell resolution and multi-region imaging in mice159
An annually resolved 5700-year storm archive reveals drivers of Caribbean cyclone frequency157
The synovial environment steers cartilage deterioration and regeneration156
Pd/Xu-Phos-catalyzed asymmetric elimination of fully substituted enol triflates into axially chiral trisubstituted allenes156
Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility155
RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS154
Dephosphorylation and ion binding in prokaryotic calcium transport154
Ocean-induced melt volume directly paces ice loss from Pine Island Glacier153
Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies153
Dynamic phase transitions dictate the size effect and activity of supported gold catalysts152
Tree-ring stable isotopes from the European Alps reveal long-term summer drying over the Holocene151
A biopolymer hydrogel electrostatically reinforced by amino-functionalized bioactive glass for accelerated bone regeneration148
Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting148
Ag-doped non–imperfection-enabled uniform memristive neuromorphic device based on van der Waals indium phosphorus sulfide147
Pathways to concealed gun carrying146
Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation144
Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity144
Long noncoding RNA DREAMer bridges the DREAM complex and E2f1 to regulate endoreplication in Drosophila143
Neuromuscular embodiment of feedback control elements in Drosophila flight143
Increasing co-occurrence of fine particulate matter and ground-level ozone extremes in the western United States142
Optimizing the timing of an end-of-outbreak declaration: Ebola virus disease in the Democratic Republic of the Congo142
Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions141
Cpeb1 remodels cell type–specific translational program to promote fear extinction141
Erratum for the Research Article: “Oscillation of type IV pili regulated by the circadian clock in cyanobacterium Synechococcus elongatus PCC7942” by Zhang <141
Inflammatory responses to acute carbon monoxide poisoning and the role of plasma gelsolin141
Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme141
A closed-loop catalytic nanoreactor system on a transistor140
Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization140
Microsecond dynamics control the HIV-1 Envelope conformation140
Real-space investigation of polarons in hematite Fe 2 O 3140
Motion Hologram: Jointly optimized hologram generation and motion planning for photorealistic 3D displays via reinforcement learning139
Depolarization block in olfactory sensory neurons expands the dimensionality of odor encoding138
Erratum for the Research Article: “TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma” by Sun et al .138
Liquid palladium for high-turnover carbon-carbon bond formation137
Considering intentional stratospheric dehydration for climate benefits137
Convergent consequences of parthenogenesis on stick insect genomes136
Broadband photodetection of intense lasers via exciton-enhanced high-order multiphoton-absorption optoelectronics in 2D hybrid perovskite136
Elder fish means more microplastics? Alaska pollock microplastic story in the Bering Sea135
Quantized critical supercurrent in SrTiO 3 -based quantum point contacts135
Maternal chemosignals enhance infant-adult brain-to-brain synchrony135
Diversification of the ruminant skull along an evolutionary line of least resistance135
Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics135
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization134
Symmetry disruption commits vault particles to disassembly134
Direct observation of multiband transport in magnonic Penrose quasicrystals via broadband and phase-resolved spectroscopy134
Significant loophole-free test of Kochen-Specker contextuality using two species of atomic ions133
Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition133
Multi-stimulus perception and visualization by an intelligent liquid metal-elastomer architecture133
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