Science Advances

Article	Citations
Ultrafast tomograms in a flash	2413
Erratum for the Research Article: “Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell”	883
Long noncoding RNA DREAMer bridges the DREAM complex and E2f1 to regulate endoreplication in Drosophila	443
Saturn’s F ring is intermittently shepherded by Prometheus	437
Developmentally programmed histone H3 expression regulates cellular plasticity at the parental-to-early embryo transition	379
Diamond-based microwave quantum amplifier	365
Enhanced Rap1 small GTPase activity in the ventral hippocampus drives stress-induced anxiety	360
Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity	349
HfZrO-based synaptic resistor circuit for a Super-Turing intelligent system	339
Orbital angular momentum–driven multistate photomemory	332
Engineering edgeless human skin with enhanced biomechanical properties	332
Time-resolving state-specific molecular dissociation with XUV broadband absorption spectroscopy	317
Rhombohedral-stacked bilayer transition metal dichalcogenides for high-performance atomically thin CMOS devices	315
Pfs230 domain 12 is a potent malaria transmission–blocking vaccine candidate	312
Optimizing the timing of an end-of-outbreak declaration: Ebola virus disease in the Democratic Republic of the Congo	312
Discovery of an autoinhibited conformation in mesotrypsin reveals a strategy for selective serine protease inhibition	309
Palimpsest memories stored in memristive synapses	306
Spinning and corkscrewing of oceanic macroplankton revealed through in situ imaging	298
Real-space investigation of polarons in hematite Fe 2 O 3	288
A molecular switch controls assembly of bacterial focal adhesions	285
Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility	277
Valence electron concentration as key parameter to control the fracture resistance of refractory high-entropy carbides	274
Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry	271
Broadband photodetection of intense lasers via exciton-enhanced high-order multiphoton-absorption optoelectronics in 2D hybrid perovskite	263
Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ	261

HIV-1 manipulates CD96 on CD4 + T cells to subvert antiviral immunity	260
Multi-stimulus perception and visualization by an intelligent liquid metal-elastomer architecture	259
Non-adapted bacterial infection suppresses plant reproduction	254
Gating of hair cell Ca 2+ channels governs the activity of cochlear neurons	248
Predicting three-component reaction outcomes from ~40,000 miniaturized reactant combinations	247
Repeated climate-driven dispersal and speciation in peripheral populations of Pleistocene mastodons	243
Arp2/3-dependent regulation of ciliogenesis governs adaptive distal tubular epithelial cell states in kidney disease	226
Multicatalysis protocol enables direct and versatile enantioselective reductive transformations of secondary amides	224
Donor HLA-DQ genetic and functional divergence affect the control of BK polyoma virus infection after kidney transplantation	221
Imaging local diffusion in microstructures using NV-based pulsed field gradient NMR	219
Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation	218
Artificial intelligence–enabled “inherited noninvasive intracellular recording” for prolonged monitoring of cardiac action potentials	217
Pathways to concealed gun carrying	216
GPCR-mediated calcium and cAMP signaling determines psychosocial stress susceptibility and resiliency	215
Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions	215
Fluid dynamical pathways of airborne transmission while waiting in a line	214
Signatures of speech and song: “Universal” links despite cultural diversity	213
Cellular stiffness sensing through talin 1 in tissue mechanical homeostasis	212
Identification of the Wnt signal peptide that directs secretion on extracellular vesicles	212
Bound chiral magnonic polariton states for ideal microwave isolation	212
Characterizing many-body dynamics with projected ensembles on a superconducting quantum processor	211
Attosecond spectroscopy reveals spontaneous symmetry breaking in molecular photoionization	204
Complementary corticostriatal circuits orchestrate action repetition and switching	204
Buffering of genetic dominance by allele-specific protein complex assembly	202
Inflammatory responses to acute carbon monoxide poisoning and the role of plasma gelsolin	200
Cold exposure stimulates cross-tissue metabolic rewiring to fuel glucose-dependent thermogenesis in brown adipose tissue	198
Depolarization block in olfactory sensory neurons expands the dimensionality of odor encoding	197
Phylogenetic tracing of midbrain-specific regulatory sequences suggests single origin of eubilaterian brains	196
A poxvirus model reveals general correlates of antigen presentation and immunogenicity for viral CD8 + T cell epitopes	195
Considering intentional stratospheric dehydration for climate benefits	195
Dynamic control of molecular transport MXene transistor membranes	194
A conserved molecular template underlies color pattern diversity in estrildid finches	193
Role of HAUS7 as a DOCK3 binding partner in facilitating axon regeneration	193
Targeting transthyretin by one Cas9 variant with superfidelity and broad compatibility	190
Editor’s note and erratum for the Research Article: “Unemployment and underemployment are causes of suicide”	187
Erratum for the Research Article: “TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma” by Sun et al .	186
Erratum for the Research Article: “Oscillation of type IV pili regulated by the circadian clock in cyanobacterium Synechococcus elongatus PCC7942” by Zha	186
Mismatched ligand density enables ordered assembly of mixed-dimensional, cross-species materials	184
Erratum for the Research Article: “SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8 + T cell cytotoxic funct	184
Low-dose metformin requires brain Rap1 for its antidiabetic action	183
Healing of ischemic injury in the retina	182
Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy	179
Emergence and reconfiguration of modular structure for artificial neural networks during continual familiarity detection	179
Optical control of 4 f orbital state in rare-earth metals	179
Real-time antiproton annihilation vertexing with submicrometer resolution	178
Early IGF-1 receptor inhibition in mice mimics preterm human brain disorders and reveals a therapeutic target	176
Upward propagation of gigantic jets revealed by 3D radio and optical mapping	176
Engineering is pregnant with possibilities	175
A computational mechanism of cue-stimulus integration for pain in the brain	175
Overexpression of the scopoletin biosynthetic pathway enhances lignocellulosic biomass processing	173

Elucidating the characteristics and clonal evolutionary trajectory of influenza neuraminidase broadly reactive B cell	173
Chaperone-mediated heterotypic phase separation regulates liquid-to-solid phase transitions of tau into amyloid fibrils	173
Driving forces of Antarctic krill abundance	171
Correlated x-ray fluorescence and ptychographic nano-tomography on Rembrandt’s The Night Watch reveals unknown lead “layer”	171
Articular fibrocartilage-targeted therapy by microtubule stabilization	170
The Plasmodium falciparum PPCS is a unique heteromeric complex with prokaryote-like activity and is a target of pantothenate analogs	169
Atomic-scale physical unclonable functions in solids	168
Transcriptional regulation of photoprotection in dark-to-light transition—More than just a matter of excess light energy	167
Efficient launching of shear phonons in photostrictive halide perovskites	166
Regulation of PD-L1 through direct binding of cholesterol to CRAC motifs	165
The potassium transporter TaNHX2 interacts with TaGAD1 to promote drought tolerance via modulating stomatal aperture in wheat	165
Rise in broadly cross-reactive adaptive immunity against human β-coronaviruses in MERS-recovered patients during the COVID-19 pandemic	165
Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells	164
Removal of trace gases can both increase and decrease cloud droplet formation	163
Real-space visualization of order-disorder transition in BaTiO 3	161
Enhancer dynamics: Unraveling the mechanism of transcriptional bursting	161
A plant NLR receptor activates auxin signaling through Aux/IAAs-ARF19 and YUC8-TIR1/AFBs to promote callose-mediated antiviral defense	161
Bacterial communities co-develop with respiratory immunity early in life, linking dysbiosis to systemic monocyte signature and wheezing	160
Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer	160
Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with reactivation routes and potential	160
Abiotic molecular oxygen production—Ionic pathway from sulfur dioxide	159
X-ray phase measurements by time-energy correlated photon pairs	159
A closed-loop catalytic nanoreactor system on a transistor	157
The genomic landscape of familial glioma	157
Molybdate uptake interplay with ROS tolerance modulates bacterial pathogenesis	157
Oral iron sulfide prevents acute alcohol intoxication by initiating the endogenous multienzymatic antioxidant defense system	157
Ultrastrong Staphylococcus aureus adhesion to human skin: Calcium as a key regulator of noncovalent interactions	156
Memristive floating-point Fourier neural operator network for efficient scientific modeling	156
Targeting TRPC channels for control of arthritis-induced bone erosion	155
Observation of dynamic nuclear polarization echoes	155
RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS	152
Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5	152
Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions	152
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization	152
Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function	151
Erratum for the Research Article “A multi-agentic framework for real-time, autonomous freeform metasurface design” by R. Lupoiu et al .	151
The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation	149
Investigating charge accumulation mechanisms in organic materials via slow transient emission spectroscopy	149
How genomic insights into the evolutionary history of clouded leopards inform their conservation	148
Hibiscus bullseyes reveal mechanisms controlling petal pattern proportions that influence plant-pollinator interactions	148
Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme	148
Magnetic fields and relativistic electrons fill entire galaxy cluster	148
Cpeb1 remodels cell type–specific translational program to promote fear extinction	147
Dephosphorylation and ion binding in prokaryotic calcium transport	146
Optical and electrical probing of plasmonic metal-molecule interactions	146
Proteome-wide computational analyses reveal links between protein condensate formation and RNA biology	146
Anabolic indices of matrix proteins identify regenerative small RNA intrinsic to human cartilage	144
Small effect of partial melt on electrical anomalies in the asthenosphere	144
Chromobacterium biopesticide overcomes insecticide resistance in malaria vector mosquitoes	144
Designing a DNA synchronizer for compact single-rail DNA logic circuits	143
Oxygen isotopes of anhydrous primary minerals show kinship between asteroid Ryugu and comet 81P/Wild2	143
Monocytic MDSCs exhibit superior immune suppression via adenosine and depletion of adenosine improves efficacy of immunotherapy	143
The molecular mechanism of sialic acid transport mediated by Sialin	142
Laws about bodily damage originate from shared intuitions about the value of body parts	142
Decoding paradoxical BOLD responses to transcranial ultrasound stimulation with concurrent optoacoustic magnetic resonance imaging	141
The extinct shark Otodus megalodon was a transoceanic superpredator: Inferences from 3D modeling	140
Real-time observation of non-equilibrium phonon-electron energy and angular momentum flow in laser-heated nickel	140
Correlated quantum machines beyond the standard second law	140
Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes	139
CysMP reveals metal ion–specific metalloproteomes and copper-regulated PGK1 activity in glycolysis	139
Munc13-1 couples DAG and Ca 2+ signaling to dynamic vesicle priming, synaptic short-term plasticity, and posttetanic potentiation	138
Particle-armored liquid robots	138
Synthesis of defect-rich La 2 O 2 CO 3 supports for enhanced CO 2	136
DNA repair during nonreductional meiosis in the asexual rotifer Adineta vaga	136
Sensory-motor circuit is a therapeutic target for dystonia musculorum mice, a model of hereditary sensory and autonomic neuropathy 6	135
Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration	135
Modularized microrobot with lock-and-detachable modules for targeted cell delivery in bile duct	135
Prebunking and credible source corrections increase election credibility: Evidence from the US and Brazil	135
Locally controllable magnetic soft actuators with reprogrammable contraction-derived motions	135
Uncovering the rapidly evolving orbits of the dynamic TOI-201 system	135
Bone-inspired stress-gaining elastomer enabled by dynamic molecular locking	134
Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments	134
Smart ultra-long-lasting sequentially triggerable and artfully implantable nozzle system for on-demand drug delivery for chronotherapy	134
Diving into the vertical dimension of elasmobranch movement ecology	134
Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury	133
AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology	132
Electrostatic nano-mask patterned 180° domain walls in a ferroelectric film	132
Direct observations of cross-scale wave-particle energy transfer in space plasmas	132
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis	132
RIPK1 inhibition reduces biliary injury and fibrosis in primary sclerosing cholangitis	132

Ordered planar plating/stripping enables deep cycling zinc metal batteries	131
Spatially entangled photon pairs from lithium niobate nonlocal metasurfaces	131
Distributed sensing along fibers for smart clothing	131
Stretchable complementary integrated electronics based on elastic dual-type transistors	131
Seeing through arthropod eyes: An AI-assisted, biomimetic approach for high-resolution, multi-task imaging	130
GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury	130
Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity	130
Ancient genomes reveal Avar-Hungarian transformations in the 9th-10th centuries CE Carpathian Basin	129
Multiplexed CRISPR-Cas9 mutagenesis of rice PSBS1 noncoding sequences for transgene-free overexpression	129
Alcaligenes faecalis corrects aberrant matrix metalloproteinase expression to promote reepithelialization of diabetic wounds	128
Distinct armchair and zigzag charge transport through single polycyclic aromatics	128
Dissecting abstract, modality-specific and experience-dependent coding of affect in the human brain	128
Spatially resolved single-cell atlas of ascidian endostyle provides insight into the origin of vertebrate pharyngeal organs	128
Structure and dynamics determine G protein coupling specificity at a class A GPCR	128
Diurnal urban rainfall anomalies across different landscapes	128
Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies	127
Biological self-protection inspired engineering of nanomaterials to construct a robust bio-nano system for environmental applications	127
Biological export production controls upper ocean calcium carbonate dissolution and CO 2 buffer capacity	127
DNA damage response pathway regulates Nrf2 in response to oxidative stress	127
Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization	127
Shear shock waves mediate haptic holography via focused ultrasound	126
Biodegradable electrospinning superhydrophilic nanofiber membranes for ultrafast oil-water separation	126
Artificial biomarker-based feedback-regulated personalized and precise thrombolysis with lower hemorrhagic risk	126
Autologous human iPSC–derived alveolus-on-chip reveals early pathological events of Mycobacterium tuberculosis infection	125
All eukaryotic SMC proteins induce a twist of −0.6 at each DNA loop extrusion step	125
Allospecific splenic Tr1 cells drive effector T cell exhaustion through up-regulated Areg-EGFR signaling to promote transplant tolerance	124
3D DNA origami pincers that multitask on giant unilamellar vesicles	124
Quantum imaging of the reconfigurable VO 2 synaptic electronics for neuromorphic computing	123
N -Heterocyclic carbene catalytic 1,2-boron migrative acylation accelerated by photocatalysis	123
Neuromuscular embodiment of feedback control elements in Drosophila flight	123
Episodic reef growth in the Last Interglacial driven by competing influence of polar ice sheets to sea level rise	123
Genome wide nucleosome landscape shapes 3D chromatin organization	122
Metabolic reprogramming in Fanconi anemia: Evidence of compromised glucose oxidation, enhanced ketogenesis, and metabolic inflexibility	122
A DNA circuit that records molecular events	122
Ag-doped non–imperfection-enabled uniform memristive neuromorphic device based on van der Waals indium phosphorus sulfide	122
Attentional guidance through object associations in visual cortex	121
Size-dependent temporal decoupling of morphogenesis and transcriptional programs in pseudoembryos	121
Pan-cortical cellular imaging in freely behaving mice using a miniaturized micro-camera array microscope (mini-MCAM)	120
CMOS-compatible electro-optical SRAM cavity device based on negative differential resistance	120
Miniature battery-free epidural cortical stimulators	119
Injectable shear-thinning hydrogels promote oligodendrocyte progenitor cell survival and remyelination in the central nervous system	119
Microsecond dynamics control the HIV-1 Envelope conformation	119
1.63-billion-year-old multicellular eukaryotes from the Chuanlinggou Formation in North China	119
An evolutionary conserved neural mechanism for interpersonal coordination in primates	118
Anthropogenic forcing has increased the risk of longer-traveling and slower-moving large contiguous heatwaves	118
Multiplexed mapping of the interactome of GPCRs with receptor activity–modifying proteins	118
Unpacking the growth of global agricultural greenhouse gas emissions	117
Compressing slippery surface-assembled amphiphiles for tunable haptic energy harvesters	117
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses	117
An annually resolved 5700-year storm archive reveals drivers of Caribbean cyclone frequency	117
Motion Hologram: Jointly optimized hologram generation and motion planning for photorealistic 3D displays via reinforcement learning	116
Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics	116
Anthropogenic warming has ushered in an era of temperature-dominated droughts in the western United States	116
Navigating high-dimensional processing parameters in organic photovoltaics via a multitier machine learning framework	116
2D material exciton-polariton transport on 2D photonic crystals	116
A printed luminescent flier inspired by plant seeds for eco-friendly physical sensing	115
Scalable generalized meta-spanners enabling parallel multitasking optical manipulation	115
A two-stage mantle plume-sagduction origin of Archean continental crust revealed by water and oxygen isotopes of TTGs	115
Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis	114
Cerebrospinal fluid flow extends to peripheral nerves further unifying the nervous system	114
Miniature color camera via flat hybrid meta-optics	114
MiniXL: An open-source, large field-of-view epifluorescence miniscope enabling single-cell resolution and multi-region imaging in mice	114
Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk	114
Comediation of voltage gating and ion charge in MXene membrane for controllable and selective monovalent cation separation	114
Distributed interfacing by nanoscale photodiodes enables single-neuron light activation and sensory enhancement in 3D spinal explants	114
The void formation behaviors in working solid-state Li metal batteries	114
Hierarchical twinning governed by defective twin boundary in metallic materials	114
27-Hydroxycholesterol acts on estrogen receptor α expressed by POMC neurons in the arcuate nucleus to modulate feeding behavior	113
Uncertainties too large to predict tipping times of major Earth system components from historical data	113
6mA-Sniper: Quantifying 6mA sites in eukaryotes at single-nucleotide resolution	113
Low-waste, single-step, sustainable extraction of critical metals from deep-sea polymetallic nodules	113
Inherent tendency of Synechococcus and heterotrophic bacteria for mutualism on long-term coexistence despite environmental interference	112
Modeling mechanical activation of macrophages during pulmonary fibrogenesis for targeted anti-fibrosis therapy	112
Role of hierarchy structure on the mechanical adaptation of self-healing hydrogels under cyclic stretching	112
Diversification of the ruminant skull along an evolutionary line of least resistance	112
Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis	112
Mechanistic insights into the roles of the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control	111
Separation and recycling of hydrofluorocarbon refrigerant mixtures with fluoropolymer-coated hollow fiber membranes	111
Metasurface-based realization of photonic time crystals	111
Atomic Sn–enabled high-utilization, large-capacity, and long-life Na anode	111
Elder fish means more microplastics? Alaska pollock microplastic story in the Bering Sea	111
Hidden white and black feather layers enhance plumage coloration in tanagers and other songbirds	111
The synovial environment steers cartilage deterioration and regeneration	111
Blind identification of the spinal cord output in humans with high-density electrode arrays implanted in muscles	110
Flash annealing–engineered wafer-scale relaxor antiferroelectrics for enhanced energy storage performance	110
Transferring strongly reducing electrons to bidentate-adsorbed CO 2 for efficient and selective formate photosynthesis	110
Pd/Xu-Phos-catalyzed asymmetric elimination of fully substituted enol triflates into axially chiral trisubstituted allenes	110
Targeting PD-1 + T cells with chimeric antigen receptors to reduce the HIV reservoir	110
Phyto-inspired sustainable and high-performance fabric generators via moisture absorption-evaporation cycles	110
LC3-associated endocytosis and the functions of Rubicon and ATG16L1	109
VARP binds SNX27 to promote endosomal supercomplex formation on membranes	109
A monolayer crystalline covalent network of polyoxometalate clusters	109
If you rise, I fall: Equality is prevented by the misperception that it harms advantaged groups	109
Tree-ring stable isotopes from the European Alps reveal long-term summer drying over the Holocene	109
An artificial intelligence enabled chemical synthesis robot for exploration and optimization of nanomaterials	108