Science Advances

Papers
(The TQCC of Science Advances is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
A bistable and reconfigurable molecular system with encodable bonds1066
Layer-resolved release of epitaxial layers in III-V heterostructure via a buffer-free mechanical separation technique1056
Glutamine antagonists may KEAP lung cancer in check747
Desensitization and belatacept-based maintenance therapy in pregnancy-sensitized monkeys receiving a kidney transplant526
The cohesin stabilizer Sororin drives G 2 -M transition and spindle assembly in mammalian oocytes410
Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals406
The energetics and ion coupling of cholesterol transport through Patched1364
A nanonewton force sensor using a U-shape tapered microfiber interferometer352
A molecular switch controls assembly of bacterial focal adhesions338
Experimental signatures of the transition from acoustic plasmon to electronic sound in graphene320
Time-independent harmonics dispersion relation for time-evolving nonlinear waves294
Treatment of epilepsy using a targeted p38γ kinase gene therapy291
Separation and recycling of hydrofluorocarbon refrigerant mixtures with fluoropolymer-coated hollow fiber membranes282
Oral iron sulfide prevents acute alcohol intoxication by initiating the endogenous multienzymatic antioxidant defense system264
Artificial biomarker-based feedback-regulated personalized and precise thrombolysis with lower hemorrhagic risk249
Genome-wide and phenome-wide studies provided insights into brain glymphatic system function and its clinical associations248
Diverse and highly differentiated lava suite in Jezero crater, Mars: Constraints on intracrustal magmatism revealed by Mars 2020 PIXL247
Functional traits mediate the effect of land use on drivers of community stability within and across trophic levels247
Distributed representations of temporally accumulated reward prediction errors in the mouse cortex241
Elucidating assembly and function of VirB8 cell wall subunits refines the DNA translocation model in Gram-positive T4SSs240
Rescue-like behavior in a bystander mouse toward anesthetized conspecifics promotes arousal via a tongue-brain connection240
Tunable polarization entangled photon-pair source in rhombohedral boron nitride238
Leptin receptor neurons in the dorsomedial hypothalamus input to the circadian feeding network237
Highly sensitive single-molecule detection of macromolecule ion beams235
Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli234
Cathodoluminescence excitation spectroscopy: Nanoscale imaging of excitation pathways234
GPCR-mediated calcium and cAMP signaling determines psychosocial stress susceptibility and resiliency233
Continued permafrost ecosystem carbon loss under net-zero and negative emissions231
Tgfβ signaling stimulates glycolysis to promote the genesis of synovial joint interzone in developing mouse embryonic limbs230
VARP binds SNX27 to promote endosomal supercomplex formation on membranes227
Quantifying CO 2 forcing effects on lightning, wildfires, and climate interactions223
Fully analog iteration for solving matrix equations with in-memory computing223
Phase separation of the poplar microtubule-associated protein PagPCaP1a aids microtubule depolymerization in response to high salt222
Human camouflage and expression via soft mask from reprogrammable chemical fluid skin220
RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells219
Optically controlling the competition between spin flips and intersite spin transfer in a Heusler half-metal on sub–100-fs time scales214
Pachytene piRNAs control discrete meiotic events during spermatogenesis and restrict gene expression in space and time206
Technical comment on “Reexamination of 2.5-Ga ‘whiff’ of oxygen interval points to anoxic ocean before GOE”203
TDP-43 safeguards the embryo genome from L1 retrotransposition203
Pd/Xu-Phos-catalyzed asymmetric elimination of fully substituted enol triflates into axially chiral trisubstituted allenes203
Osmotrophy of dissolved organic compounds by coccolithophore populations: Fixation into particulate organic and inorganic carbon202
Mechanistic insights into the roles of the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control201
Innovation and elaboration on the avian tree of life199
Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions198
UFMylation of MRE11 is essential for telomere length maintenance and hematopoietic stem cell survival197
Efficient nonreciprocal mode transitions in spatiotemporally modulated acoustic metamaterials196
Systematic inference identifies a major source of heterogeneity in cell signaling dynamics: The rate-limiting step number194
Three-dimensional sensing of surfaces by projection of invisible electroluminescence from organic light-emitting diodes192
Causal inference from text: A commentary192
Temperature sensitivity of the mineral permafrost feedback at the continental scale190
The massive 2016 marine heatwave in the Southwest Pacific: An “El Niño–Madden-Julian Oscillation” compound event190
Chromatic acclimation shapes phytoplankton biogeography189
Shortcuts to adiabatic non-Abelian braiding on silicon photonic chips187
Accelerated internal tides in a warming climate185
Finding independent sets in large-scale graphs with a coherent Ising machine185
Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration184
Sequential multidimensional heteroepitaxy of chalcogen-sharing 3D ZnSe and 2D MoSe 2 with quasi van der Waals interface engineering182
Nonreciprocal chirality conversion in spatiotemporal evolutions of nematic colloidal entanglement181
Ag-doped non–imperfection-enabled uniform memristive neuromorphic device based on van der Waals indium phosphorus sulfide180
A bacterial tungsten-containing aldehyde oxidoreductase forms an enzymatic decorated protein nanowire180
Decreasing Wapl dosage partially corrects embryonic growth and brain transcriptome phenotypes in Nipbl +/− 180
Ocean-induced melt volume directly paces ice loss from Pine Island Glacier179
Smaug regulates germ plasm assembly and primordial germ cell number in Drosophila embryos178
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms177
Historical insights at scale: A corpus-wide machine learning analysis of early modern astronomic tables174
Cotranscriptionally encoded RNA strand displacement circuits173
Sunlight-driven dissolution is a major fate of oil at sea172
H3K4me3 recognition by the COMPASS complex facilitates the restoration of this histone mark following DNA replication172
Targeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases172
3D DNA origami pincers that multitask on giant unilamellar vesicles171
Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses171
Optimizing the timing of an end-of-outbreak declaration: Ebola virus disease in the Democratic Republic of the Congo171
Demonstration of electric micropropulsion multimodality170
Recognitions of colored fabrics/laser-patterned metals based on photothermoelectric effects170
How does salinity shape ocean circulation and ice geometry on Enceladus and other icy satellites?169
Leaftronics: Natural lignocellulose scaffolds for sustainable electronics168
LC3-associated endocytosis and the functions of Rubicon and ATG16L1168
Iron regulatory protein (IRP)–mediated iron homeostasis is critical for neutrophil development and differentiation in the bone marrow167
Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity165
Ultrasonic tweezer for multifunctional droplet manipulation164
Millimeter-scale soft capsules for sampling liquids in fluid-filled confined spaces163
It happened again: Convergent evolution of acylglucose specialized metabolism in black nightshade and wild tomato162
“Omics” data unveil early molecular response underlying limb regeneration in the Chinese mitten crab, Eriocheir sinensis162
The emergence of spontaneous coordinated epithelial rotation on cylindrical curved surfaces161
Myeloid-derived growth factor inhibits inflammation and alleviates endothelial injury and atherosclerosis in mice159
IFN-λ derived from nonsusceptible enterocytes acts on tuft cells to limit persistent norovirus159
Membrane potential stimulates ADP import and ATP export by the mitochondrial ADP/ATP carrier due to its positively charged binding site156
Two horizontally acquired bacterial genes steer the exceptionally efficient and flexible nitrogenous waste cycling in whiteflies155
Creating chromaticity palettes and identifying white light emitters through nanocrystal megalibraries155
Maximizing efficiency of dipolar recoupling in solid-state NMR using optimal control sequences153
Plasma iron controls neutrophil production and function153
Cerebrospinal fluid flow extends to peripheral nerves further unifying the nervous system152
Imaging the coherent propagation of collective modes in the excitonic insulator Ta 2 NiSe 5 at room temperature152
Effector memory–type regulatory T cells display phenotypic and functional instability152
Oxygen isotopes of anhydrous primary minerals show kinship between asteroid Ryugu and comet 81P/Wild2152
Delocalized quinolinium-macrocyclic peptides, an atypical chemotype for CNS penetration151
Progressive alterations in amino acid and lipid metabolism correlate with peripheral neuropathy in Polg D257A mice151
The boundary for quantum advantage in Gaussian boson sampling151
In vivo correction of cystic fibrosis mediated by PNA nanoparticles150
Evidence for enormous iodide anion migration in lanthanum oxyiodide–based solid149
Negative reflection of nanoscale-confined polaritons in a low-loss natural medium149
Re-identification of individuals in genomic datasets using public face images149
ATM deficiency confers specific therapeutic vulnerabilities in bladder cancer146
Earth’s carbon deficit caused by early loss through irreversible sublimation146
Discovery of primitive CO 2 -bearing fluid in an aqueously altered carbonaceous chondrite145
SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression145
Discovering a uniform functional trade-off of the CBC-type 2,3-oxidosqualene cyclases and deciphering its chemical logic145
Mesostriatal dopamine is sensitive to changes in specific cue-reward contingencies145
Metal-organic frameworks with fine-tuned interlayer spacing for microwave absorption144
A versatile jellyfish-like robotic platform for effective underwater propulsion and manipulation144
Buffering of genetic dominance by allele-specific protein complex assembly143
Physics-based generative model of curvature sensing peptides; distinguishing sensors from binders143
No evidence of supracrustal recycling in Si-O isotopes of Earth’s oldest rocks 4 Ga ago143
Temporal disparity of action potentials triggered in axon initial segments and distal axons in the neocortex142
The molecular mechanism of sialic acid transport mediated by Sialin141
Emergence and inversion of chirality in hierarchical assemblies of CdS nanocrystal fibers141
Assessing cancer therapeutic efficacy in vivo using [ 2 H 7 ]glucose deuterium metabolic imaging140
Local and long-range input balance: A framework for investigating frontal cognitive circuit maturation in health and disease140
Submicroscopic magnetite may be ubiquitous in the lunar regolith of the high-Ti region140
Chiral electroluminescence from thin-film perovskite metacavities139
Theory cracks old data: Rovibrational energy levels of ortho H 2 –CO derived from experiment139
Proteogenomic discovery of RB1 -defective phenocopy in cancer predicts disease outcome, response to treatment, and therapeutic targets138
Imaging with a twist: Three-dimensional insights of the chiral nematic phase of cellulose nanocrystals via SHG microscopy138
Observing separate spin and charge Fermi seas in a strongly correlated one-dimensional conductor137
Macrophage-targeted Mms6 mRNA-lipid nanoparticles promote locomotor functional recovery after traumatic spinal cord injury in mice137
Primary specification of blastocyst trophectoderm by scRNA-seq: New insights into embryo implantation136
Proteasome-associated ubiquitin ligase relays target plant hormone-specific transcriptional activators136
Rationalized design of hyperbranched trans-scale graphene arrays for enduring high-energy lithium metal batteries136
Human-level few-shot concept induction through minimax entropy learning135
Disproportionation chemistry in K 2 PtCl 4 visualized at atomic resolution using scanning transmission electron microscopy135
Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs133
Pri peptides temporally coordinate transcriptional programs during epidermal differentiation133
Tensor networks enable the calculation of turbulence probability distributions132
Compressing slippery surface-assembled amphiphiles for tunable haptic energy harvesters132
Brownian lithographic polymers of steric lock-and-key colloidal linkages132
Motion Hologram: Jointly optimized hologram generation and motion planning for photorealistic 3D displays via reinforcement learning131
One-dimensional nanosonosensitizer boosted multiple branches of immune responses against MHC-deficient immune-evasive urologic tumor130
Dispersive heterodyne cavity ring-down spectroscopy exploiting eigenmode frequencies for high-fidelity measurements130
A multi-analytical study of the Montelirio beaded attires: Marine resources, sumptuary crafts, and female power in copper age Iberia130
Temporal dynamics of the interstitial fluid proteome in human skeletal muscle following exhaustive exercise129
Soft multifunctional bistable fabric mechanism for electronics-free autonomous robots129
Optical control of 4 f orbital state in rare-earth metals128
Mitochondrial energy state controls AMPK-mediated foraging behavior in C. elegans127
Unlocking iron metal as a cathode for sustainable Li-ion batteries by an anion solid solution126
Drought- and heat-induced mortality of conifer trees is explained by leaf and growth legacies125
XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes125
Toward perturbation theory methods on a quantum computer125
Dissecting the evolutionary role of the Hox gene proboscipedia in Drosophila mouthpart diversification by f125
Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization124
Ambivalent attitudes promote support for extreme political actions124
Experimental and computational understanding of pulsatile release mechanism from biodegradable core-shell microparticles124
Ultrarapid lytic granule release from CTLs activates Ca 2+ -dependent synaptic resistance pathways in melanoma cells124
Origin of photoinduced DC current and two-level population dynamics in a single molecule123
Twilight length alters growth and flowering time in Arabidopsis via LHY / CCA1123
Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization122
TOP CAR with TMIGD2 as a safe and effective costimulatory domain in CAR cells treating human solid tumors122
Layer by layer, spin by spin122
Megathrust locking encoded in subduction landscapes121
Observation of others’ painful heat stimulation involves responses in the spinal cord120
Structure of TFIIK for phosphorylation of CTD of RNA polymerase II120
Cost-effective implementation of the Paris Agreement using flexible greenhouse gas metrics120
Genetically determined thymic function affects strength and duration of immune response in COVID patients with pneumonia120
ERK signaling mediates resistance to immunomodulatory drugs in the bone marrow microenvironment119
Retromer stabilizes transient membrane insertion of L2 capsid protein during retrograde entry of human papillomavirus118
αβ/γδ T cell lineage outcome is regulated by intrathymic cell localization and environmental signals118
Large-scale, robust mushroom-shaped nanochannel array membrane for ultrahigh osmotic energy conversion118
Sparse ab initio x-ray transmission spectrotomography for nanoscopic compositional analysis of functional materials118
The coherence of light is fundamentally tied to the quantum coherence of the emitting particle118
Multiple integrated metabolic strategies allow foraminiferan protists to thrive in anoxic marine sediments118
Bioinspired electrospun dECM scaffolds guide cell growth and control the formation of myotubes118
PHF8-promoted TOPBP1 demethylation drives ATR activation and preserves genome stability118
A malaria parasite phospholipid flippase safeguards midgut traversal of ookinetes for mosquito transmission118
Ultrafast electron cycloids driven by the transverse spin of a surface acoustic wave117
Looping-in complexation and ion partitioning in nonstoichiometric polyelectrolyte mixtures117
Dichotomous dopaminergic and noradrenergic neural states mediate distinct aspects of exploitative behavioral states117
X-ray free-electron laser studies reveal correlated motion during isopenicillin N synthase catalysis116
Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ116
Sex or cannibalism: Polyphenism and kin recognition control social action strategies in nematodes116
Molecular mechanism for kinesin-1 direct membrane recognition116
New mechanism and exact theory of superconductivity from strong repulsive interaction116
Role of warm subduction in the seismological properties of the forearc mantle: An example from southwest Japan116
Root-knot nematode chemotaxis is positively regulated by l -galactose sidechains of mucilage carbohydrate rhamnogalacturonan-I116
Identification and architecture of a putative secretion tube across mycobacterial outer envelope115
Spatial concepts of number, size, and time in an indigenous culture115
The Trojan-horse mechanism: How networks reduce gender segregation114
Rampant prophage movement among transient competitors drives rapid adaptation during infection114
Budding yeast relies on G 1 cyclin specificity to couple cell cycle progression with morphogenetic development114
The major mechanism of melanoma mutations is based on deamination of cytosine in pyrimidine dimers as determined by circle damage sequencing114
Diversification dynamics of total-, stem-, and crown-groups are compatible with molecular clock estimates of divergence times114
Combining generative artificial intelligence and on-chip synthesis for de novo drug design114
A variable-gain stochastic pooling motif mediates information transfer from receptor assemblies into NF-κB114
Molecular growth of PANH via intermolecular Coulombic decay113
Neutral quasispecies evolution and the maximal entropy random walk113
Low-energy room-temperature optical switching in mixed-dimensionality nanoscale perovskite heterojunctions113
Miniature battery-free epidural cortical stimulators113
Synchronized and asynchronous modulation of seismicity by hydrological loading: A case study in Taiwan113
Belief propagation for networks with loops113
Basal nucleation and the prevalence of ascending swarms in Long Valley caldera113
Probing surface Earth reactive silica cycling using stable Si isotopes: Mass balance, fluxes, and deep time implications113
Charge transport physics of a unique class of rigid-rod conjugated polymers with fused-ring conjugated units linked by double carbon-carbon bonds113
Cork-in-bottle mechanism of inhibitor binding to mammalian complex I112
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling112
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice112
Photoactivated voltage imaging in tissue with an archaerhodopsin-derived reporter112
Rolling spinners on the water surface112
Single-molecule measurements reveal that PARP1 condenses DNA by loop stabilization111
Charge order lock-in by electron-phonon coupling in La 1.675 Eu 0.2 Sr 0.125 CuO 111
Differential recognition of oligomannose isomers by glycan-binding proteins involved in innate and adaptive immunity111
Posttranslational regulation of FOXA1 by Polycomb and BUB3/USP7 deubiquitin complex in prostate cancer111
Experimental quantum conference key agreement111
Experimental observation of the elastic range scaling in turbulent flow with polymer additives110
Switchable positioning of plate-like inclusions in lipid membranes: Elastically mediated interactions of planar colloids in 2D fluids110
Population genomic evidence of Plasmodium vivax Southeast Asian origin110
Semibrittle seismic deformation in high-temperature mantle mylonite shear zone along the Romanche transform fault110
Upward propagation of gigantic jets revealed by 3D radio and optical mapping109
Imaging local diffusion in microstructures using NV-based pulsed field gradient NMR109
Uncertainties too large to predict tipping times of major Earth system components from historical data108
Disruption of proteome by an oncogenic fusion kinase alters metabolism in fibrolamellar hepatocellular carcinoma108
Controlling and visualizing Dirac physics in topological semimetal heterostructures108
In situ imaging of the three-dimensional shape of soft responsive particles at fluid interfaces by atomic force microscopy108
Plasmid hypermutation using a targeted artificial DNA replisome108
Optical imaging reveals chemotherapy-induced metabolic reprogramming of residual disease and recurrence108
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses108
First measurements of low-energy cosmic rays on the surface of the lunar farside from Chang’E-4 mission108
Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy107
The extinct shark Otodus megalodon was a transoceanic superpredator: Inferences from 3D modeling107
Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans107
Stat5 induces androgen receptor ( AR ) gene transcription in prostate cancer and offers a druggable pathway to target AR signaling107
A general pattern of trade-offs between ecosystem resistance and resilience to tropical cyclones107
Modulating environmental signals to reveal mechanisms and vulnerabilities of cancer persisters107
Structures of artificially designed discrete RNA nanoarchitectures at near-atomic resolution107
Structure and function of GluN1-3A NMDA receptor excitatory glycine receptor channel107
Subsecond fluctuations in extracellular dopamine encode reward and punishment prediction errors in humans107
Mutation-induced DNMT1 cleavage drives neurodegenerative disease107
GPR15L is an epithelial inflammation-derived pruritogen107
Curving expectations: The minimal impact of structural curvature in biological puncture mechanics106
Secular change of true polar wander over the past billion years106
Water isotope ratios reflect convection intensity rather than rain type proportions in the pantropics106
N -Heterocyclic carbene catalytic 1,2-boron migrative acylation accelerated by photocatalysis105
Ultrashort 15-nm flexible radio frequency ITO transistors enduring mechanical and temperature stress105
Carbon capture in polymer-based electrolytes105
Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry104
Mismatched ligand density enables ordered assembly of mixed-dimensional, cross-species materials104
Risk scores, label bias, and everything but the kitchen sink104
Diamond-based microwave quantum amplifier104
Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages103
Real-time observation of non-equilibrium phonon-electron energy and angular momentum flow in laser-heated nickel103
Human population dynamics in Upper Paleolithic Europe inferred from fossil dental phenotypes103
Miniature color camera via flat hybrid meta-optics103
Mechanism of stress-induced attacks in an episodic neurologic disorder103
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