OOIR: Observatory of International Research

Papers

(The H4-Index of JCI Insight is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Reverse electrical remodeling in rats with heart failure and preserved ejection fraction	152
Human-specific elimination of epithelial Siglec-XII suppresses the risk of inflammation driven colorectal cancers	134
Unique T cell signatures associated with reduced Chlamydia trachomatis reinfection in a highly exposed cohort	130
N-glycosylation in the SERPIN domain of the C1-esterase inhibitor in hereditary angioedema	125
Constitutive deletion of the obscurin-Ig58/59 domains induces atrial remodeling and Ca2+-based arrhythmogenesis	122
Prothrombin prevents fatal T cell–dependent anemia during chronic virus infection of mice	115
The impact of remdesivir on SARS-CoV-2 evolution in vivo	108
T follicular regulatory cells in food allergy promote IgE via IL-4	107
Endothelial deletion of adipose triglyceride lipase protects against heart failure with preserved ejection fraction	102
A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection	101
Hepatic HIF2 is a key determinant of manganese excess and polycythemia in SLC30A10 deficiency	91
IFN-signaling gene expression as a diagnostic biomarker for monogenic interferonopathies	89
Fibrotic lung disease inhibits immune responses to staphylococcal pneumonia via impaired neutrophil and macrophage function	88
SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside	84
Immunopathogenesis of hidradenitis suppurativa and response to anti–TNF-α therapy	83
Myosin folding boosts solubility in cardiac muscle sarcomeres	82
Distinct tumor microenvironment makes anaplastic thyroid cancer more lethal but immunotherapy-sensitive than papillary thyroid cancer	80
Obesity modulates NK cell activity via LDL and DUSP1 signaling for populations with adverse social determinants	78
Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV	75
Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice	73
Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling	73
T cell responses and clinical symptoms among infants with congenital cytomegalovirus infection	72
Dysregulated immunologic landscape of the early host response in melioidosis	72
Molecular subtyping improves breast cancer diagnosis in the Copenhagen Breast Cancer Genomics Study	71
Preclinical spheroid models identify BMX as a therapeutic target for metastatic MYCN nonamplified neuroblastoma	70

Activation of autoreactive lymphocytes in the lung by STING gain-of-function mutation expressing radioresistant cells	69
Diurnal rhythms in varicella vaccine effectiveness	68
Neuronal SLC39A8 deficiency impairs cerebellar development by altering manganese homeostasis	68
Development of a humanized mouse model with functional human materno-fetal interface immunity	68
YY1 regulation by miR-124-3p promotes Th17 cell pathogenicity through interaction with T-bet in rheumatoid arthritis	66
Indoleamine-2,3-dioxygenase inhibition improves immunity and is safe for concurrent use with cART during Mtb/SIV coinfection	66
Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection	66
Norepinephrine induces anoikis resistance in high-grade serous ovarian cancer precursor cells	65
Adaptive immune responses in vaccinated patients with symptomatic SARS-CoV-2 Alpha infection	64
Glucose-dependent insulinotropic polypeptide receptor signaling alleviates gut inflammation in mice	64
Cell differentiation is disrupted by MYO5B loss through Wnt/Notch imbalance	63
Abortion rights are health care rights	62
TAp63, a methotrexate target in CD4+ T cells, suppresses Foxp3 expression and exacerbates autoimmune arthritis	61
miR–9-5p regulates immunometabolic and epigenetic pathways in β-glucan–trained immunity via IDH3α	60
Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency	60
Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis	59
Pivotal roles for cancer cell–intrinsic mPGES-1 and autocrine EP4 signaling in suppressing antitumor immunity	59
Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice	59
Endothelial cell–specific LAT1 ablation normalizes tumor vasculature	59
(Pro)renin receptor signaling in hypothalamic tyrosine hydroxylase neurons is required for obesity-associated glucose metabolic impairment	58
Growth factors with valproic acid restore injury-impaired hearing by promoting neuronal regeneration	58
EZH2 deletion does not affect acinar regeneration but restricts progression to pancreatic cancer in mice	58
Nucleolin promotes angiogenesis and endothelial metabolism along the oncofetal axis in the human brain vasculature	57
Tumor-infiltrating exhausted CD8+ T cells dictate reduced survival in premenopausal estrogen receptor–positive breast cancer	57
Interferon-dependent signaling is critical for viral clearance in airway neutrophils	56
Gaps between college and starting an MD-PhD program are adding years to physician-scientist training time	56
Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation	55
Endothelial TDP-43 controls sprouting angiogenesis and vascular barrier integrity, and its deletion triggers neuroinflammation	53