JCI Insight

Article	Citations
Allergen induces pulmonary neuroendocrine cell hyperplasia in a model of asthma	187
A hypomorphic Mpi mutation unlocks an in vivo tool for studying global N-glycosylation deficiency	144
Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models	133
Fibrotic lung disease inhibits immune responses to staphylococcal pneumonia via impaired neutrophil and macrophage function	124
Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection	119
Combinatorial transcription factor profiles predict mature and functional human islet α and β cells	113
Recurrent moderate hypoglycemia accelerates the progression of Alzheimer’s disease through impairment of the TRPC6/GLUT3 pathway	108
Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis	96
Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice	95
Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas	95
A dominant pathogenic MEFV mutation causes atypical pyrin-associated periodic syndromes	92
11C-Para-aminobenzoic acid PET imaging of S. aureus and MRSA infection in preclinical models and humans	86
Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection	86
EBAG9 controls CD8+ T cell memory formation responding to tumor challenge in mice	85
AXL inhibition suppresses early allograft monocyte-to-macrophage differentiation and prolongs allograft survival	78
Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV	78
Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses	77
LMAN1 serves as a cargo receptor for thrombopoietin	77
Effects of SIPA1L1 on trabecular meshwork extracellular matrix protein accumulation and cellular phagocytosis in POAG	76
The CLCA1/TMEM16A/Cl– current axis associates with H2S deficiency in diabetic kidney injury	76
Glucose-dependent insulinotropic polypeptide receptor signaling alleviates gut inflammation in mice	73
CNS-dominant human FMRP isoform rescues seizures, fear, and sleep abnormalities in Fmr1-KO mice	73
Bariatric surgery improves postprandial VLDL kinetics and restores insulin-mediated regulation of hepatic VLDL production	72
Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation	70
Interferon-dependent signaling is critical for viral clearance in airway neutrophils	67

Hypoxia-activated prodrug and antiangiogenic therapies cooperatively treat pancreatic cancer but elicit immunosuppressive G-MDSC infiltration	66
Dipeptidase-1–knockout mice develop invasive tumors with features of microsatellite-unstable colorectal cancer	65
Endothelial deletion of adipose triglyceride lipase protects against heart failure with preserved ejection fraction	64
TIAM1 acts as an actin organization regulator to control adipose tissue–derived pericyte cell fate	64
Lipidomic profiling of human adiposomes identifies specific lipid shifts linked to obesity and cardiometabolic risk	63
De novo variant in RING finger protein 213 causes systemic vasculopathy	63
The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention	62
Endothelial-derived FABP4 constitutes the majority of basal circulating hormone and regulates lipolysis-driven insulin secretion	62
UBE3A expression during early postnatal brain development is required for proper dorsomedial striatal maturation	61
Nociceptor neurons promote IgE class switch in B cells	61
Multicomponent parenteral lipid emulsions do not prevent liver injury in neonatal pigs with obstructive cholestasis	60
Coimmunomodulation of tumor and tumor-draining lymph nodes during in situ vaccination promotes antitumor immunity	60
Key patient demographics shape innate immune topography in noncritical hypoxic COVID-19 pneumonia	60
Calcineurin inhibitors stimulate Kir4.1/Kir5.1 of the distal convoluted tubule to increase NaCl cotransporter	59
Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes	59
Development of a humanized mouse model with functional human materno-fetal interface immunity	58
Pharmacological induction of MHC-I expression in tumor cells revitalizes T cell antitumor immunity	58
Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells	56
Dysregulated immunologic landscape of the early host response in melioidosis	55
Irx1 mechanisms for oral epithelial basal stem cell plasticity during reepithelialization after injury	54
CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis	54
Assemblies of JAG1 and JAG2 determine tracheobronchial cell fate in mucosecretory lung disease	54
Autosomal-dominant macular dystrophy linked to a chromosome 17 tandem duplication	54
Longitudinal lipidomic profiles of left ventricular mass and left ventricular hypertrophy in American Indians	54
Lipidomics of infant mesenchymal stem cells associate with the maternal milieu and child adiposity	53
Durability of ChAdOx1 nCoV-19 vaccination in people living with HIV	52
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy	52
Constitutive deletion of the obscurin-Ig58/59 domains induces atrial remodeling and Ca2+-based arrhythmogenesis	52
Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis	51
T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade	50
Epac1–/– and Epac2–/– mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation	50
BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia	50
Myocardial ATP depletion detected noninvasively predicts sudden cardiac death risk in patients with heart failure	49
Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition	49
Allelic heterogeneity of TTNtv dilated cardiomyopathy can be modeled in adult zebrafish	49
Pregnancy dedifferentiates memory CD8+ T cells into hypofunctional cells with exhaustion-enriched programs	49
Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation	49
Type I interferons and TGF-β cooperate to induce liver fibrosis during HIV-1 infection under antiretroviral therapy	49
IL-15 reprogramming compensates for NK cell mitochondrial dysfunction in HIV-1 infection	47
ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression	47
hsa-miRNA-548v controls the viscoelastic properties of human cardiomyocytes and improves their relaxation rates	47
NSD1-916aa encoded by CircNSD1 contributes to AKI-to-CKD transition through inducing ferroptosis in tubular epithelial cells	47
First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival	47
Caspase-4/11 promotes hyperlipidemia and chronic kidney disease-accelerated vascular inflammation by enhancing trained immunity	47
Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models	47
Rapamycin immunomodulation utilizes time-dependent alterations of lymph node architecture, leukocyte trafficking, and gut microbiome	46
Longitudinal associations of insulin resistance with change in bone mineral density in midlife women	46
Prenatal alcohol exposure is associated with altered feto-placental blood flow and sex-specific placental changes	46
Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later life	46
Intragraft memory-like CD127hiCD4+Foxp3+ Tregs maintain transplant tolerance	45

A versatile laser-induced porcine model of outer retinal and choroidal degeneration for preclinical testing	45
Duration of viral shedding and culture positivity with postvaccination SARS-CoV-2 delta variant infections	45
Antisense oligonucleotide treatment rescues UBE3A expression and multiple phenotypes of an Angelman syndrome mouse model	45
A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects	45
Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial	45
Bacterial cancer therapy in autochthonous colorectal cancer affects tumor growth and metabolic landscape	45
Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease	45
Focusing HIV-1 Gag T cell responses to highly conserved regions by DNA vaccination in HVTN 119	44
Obesity and diabetes are major risk factors for epicardial adipose tissue inflammation	44
Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease	44
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease	44
Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting	44
New insights into an old question: can the MD-PhD physician-scientist pipeline be improved?	44
Horizontal transmission of gut microbiota attenuates mortality in lung fibrosis	44
SPOP mutations increase PARP inhibitor sensitivity via CK2/PIAS1/SPOP axis in prostate cancer	43
Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population	43
CAVIN3 deficiency promotes vascular normalization in ocular neovascular disease via ERK/JAG1 signaling pathway	43
Mutational landscape of atherosclerotic plaques reveals large clonal cell populations	43
Intimomedial tears of the aorta heal by smooth muscle cell–mediated fibrosis without atherosclerosis	42
Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep	42
Evidence of a Sjögren’s disease–like phenotype following COVID-19 in mice and humans	42
Islet transplantation into brown adipose tissue can delay immune rejection	42
Profound reduction of HIV-1 reservoir cells over 3 decades of antiretroviral therapy started in early infancy	42
A single-cell atlas of the myometrium in human parturition	42
HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ART	41
Multiantigen pan-sarbecovirus DNA vaccines generate protective T cell immune responses	41
HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury	41
Immunological landscape of human lymphoid explants during measles virus infection	41
Immune and epithelial determinants of age-related risk and alveolar injury in fatal COVID-19	41
Regulation of human and mouse bystander T cell activation responses by PD-1	41
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort	41
Protein kinase G2 activation restores Wnt signaling and bone mass in glucocorticoid-induced osteoporosis in mice	40
Histone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells	40
Atypical response to bacterial coinfection and persistent neutrophilic bronchoalveolar inflammation distinguish critical COVID-19 from influenza	40
Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation	40
FGF receptors mediate cellular senescence in the cystic fibrosis airway epithelium	39
Mitochondria-sequestered Aβ renders synaptic mitochondria vulnerable in the elderly with a risk of Alzheimer disease	39
The hepatokine TSK maintains myofiber integrity and exercise endurance and contributes to muscle regeneration	39
Elevated apolipoprotein C3 augments diabetic kidney disease and associated atherosclerosis in type 2 diabetes	39
Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling	38
Adrenal-permissive HSD3B1 genetic inheritance and risk of estrogen-driven postmenopausal breast cancer	38
Single-cell landscape analysis unravels molecular programming of the human B cell compartment in chronic GVHD	38
A systematic review of geographic indices of disadvantage with implications for older adults	38
SARS-CoV-2–associated ssRNAs activate inflammation and immunity via TLR7/8	38
Inflammation-type dysbiosis of the oral microbiome associates with the duration of COVID-19 symptoms and long COVID	38
Allele-specific silencing of the gain-of-function mutation in Huntington’s disease using CRISPR/Cas9	38
mTOR inhibition overcomes RSK3-mediated resistance to BET inhibitors in small cell lung cancer	37
Responders to low-dose ATG induce CD4+ T cell exhaustion in type 1 diabetes	37
Effects of FGF21, soluble TGFBR2, and environmental temperature on metabolic dysfunction in lipodystrophic mice	37
Transcriptome and microbiome-immune changes across preinvasive and invasive anal cancer lesions	37
Uric acid formation is driven by crosstalk between skeletal muscle and other cell types	36
Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation	36
Predictive value of TCR Vβ-Jβ profile for adjuvant gefitinib in EGFR mutant NSCLC from ADJUVANT-CTONG 1104 trial	36
A dynamic mucin mRNA signature associates with COVID-19 disease presentation and severity	36
Cord blood proteomics identifies biomarkers of early-onset neonatal sepsis	36
Involvement of impaired carnitine-induced fatty acid oxidation in experimental and human diabetic kidney disease	36
DAB2IP loss in luminal a breast cancer leads to NF-κB–associated aggressive oncogenic phenotypes	36
Deciphering the tumor microenvironment cell–infiltrating landscape reveals microenvironment subtypes and therapeutic potentials for nonsquamous NSCLC	36
Endothelial response to blood-brain barrier disruption in the human brain	36
Ebola virus protein VP40 stimulates IL-12– and IL-18–dependent activation of human natural killer cells	36
IFN-λ uniquely promotes CD8 T cell immunity against SARS-CoV-2 relative to type I IFN	36
Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota	36
Circulating extracellular vesicles in human cardiorenal syndrome promote renal injury in a kidney-on-chip system	36
Identification and validation of a T cell receptor targeting KRAS G12V in HLA-A*11:01 pancreatic cancer patients	35
SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways	35
Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer	35
Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells	35
Single-cell RNA-Seq of human esophageal epithelium in homeostasis and allergic inflammation	35
Expansion of the HSV-2–specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine	35
SLC6A19 inhibition facilitates urinary neutral amino acid excretion and lowers plasma phenylalanine	35
β Cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood	34
β-Catenin disruption decreases macrophage exosomal α-SNAP and impedes Treg differentiation in acute liver injury	34
Restoring calcium homeostasis in Purkinje cells arrests neurodegeneration and neuroinflammation in the ARSACS mouse model	34
An immunosuppressed microenvironment distinguishes lateral ventricle–contacting glioblastomas	34
In vivo AAV9-Myo7a gene rescue restores hearing and cholinergic efferent innervation in inner hair cells	34
CD34hi subset of synovial fibroblasts contributes to fibrotic phenotype of human knee osteoarthritis	34
Rapid systemic spread and minimal immune responses following SIVsab intrarectal transmission in African green monkeys	34
Mechanisms underlying age-associated exacerbation of pulmonary veno-occlusive disease	34
SARA suppresses myofibroblast precursor transdifferentiation in fibrogenesis in a mouse model of scleroderma	34
Temporal development of T cell receptor repertoires during childhood in health and disease	34

Piperlongumine overcomes osimertinib resistance via governing ubiquitination-modulated Sp1 turnover	33
The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas	33
Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function	33
Oxygen-carrying nanoemulsions and respiratory hyperoxia eliminate tumor hypoxia–induced immunosuppression	33
Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response	33
Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus	33
Spatiotemporal mapping of immune and stem cell dysregulation after volumetric muscle loss	33
Association of oxidized ApoB and oxidized ApoA-I with high-risk coronary plaque features in cardiovascular disease	33
Modeling skeletal dysplasia in Hurler syndrome using patient-derived bone marrow osteoprogenitor cells	33
Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment	33
NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE	33
S-nitrosylation attenuates pregnane X receptor hyperactivity and acetaminophen-induced liver injury	33
Intergenic sequences harboring potential enhancer elements contribute to Axenfeld-Rieger syndrome by regulating PITX2	33
Cross-species single-cell analysis uncovers the immunopathological mechanisms associated with IgA nephropathy progression	33
The aberrant tonsillar microbiota modulates autoimmune responses in rheumatoid arthritis	32
Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators	32
Hedgehog activation promotes osteogenic fates of growth plate resting zone chondrocytes through transient clonal competency	32
LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3	32
Dichloroacetate improves mitochondrial function, physiology, and morphology in FBXL4 disease models	32
Endothelium-protective, histone-neutralizing properties of the polyanionic agent defibrotide	32
suPAR links a dysregulated immune response to tissue inflammation and sepsis-induced acute kidney injury	32
Single-nucleus RNA-Seq reveals singular gene signatures of human ductal cells during adaptation to insulin resistance	32
Evaluating precision medicine approaches for gene therapy in patient-specific cellular models of Bietti crystalline dystrophy	32
Anoctamin-5 deficiency enhances ATG9A-dependent autophagy, inducing osteogenesis and gnathodiaphyseal dysplasia–like bone formation	32
Functional Pdgfra fibroblast heterogeneity in normal and fibrotic mouse lung	32
Orai1 calcium channel inhibition prevents progression of chronic pancreatitis	31
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma	31
ABT1 modifies SMARD1 pathology via interactions with IGHMBP2 and stimulation of ATPase and helicase activity	31
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART	31
Inhibition of the renin-angiotensin system causes concentric hypertrophy of renal arterioles in mice and humans	31
Ancestry-based differences in the immune phenotype are associated with lupus activity	31
A phase I study of autologous mesenchymal stromal cells for severe steroid-dependent nephrotic syndrome	31
ADAM17-mediated EGFR ligand shedding directs macrophage-promoted cancer cell invasion	31
Chronic pharmacologic manipulation of dopamine transmission ameliorates metabolic disturbance in Trappc9-linked brain developmental syndrome	31
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout mice	31
DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3	31
Preservation of naive-phenotype CD4+ T cells after vaccination contributes to durable immunity	31
Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice	31
PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils	30
Bioactive extracellular vesicles from a subset of endothelial progenitor cells rescue retinal ischemia and neurodegeneration	30
IL-33 activates group 2 innate lymphoid cell expansion and modulates endometriosis	30
The gut microbiome enhances breast cancer immunotherapy following bariatric surgery	30
Endothelial PRMT5 plays a crucial role in angiogenesis after acute ischemic injury	30
4PBA reduces growth deficiency in osteogenesis imperfecta by enhancing transition of hypertrophic chondrocytes to osteoblasts	30
Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells	30
Inhibition of ceramide accumulation in AdipoR1–/– mice increases photoreceptor survival and improves vision	30
KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis	29
Heterogeneity of thymic output in the elderly and its association with sex and smoking	29
Leukocytes mediate disease pathogenesis in the Ndufs4(KO) mouse model of Leigh syndrome	29
HSPA12A maintains aerobic glycolytic homeostasis and Histone3 lactylation in cardiomyocytes to attenuate myocardial ischemia/reperfusion injury	29
Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis	29
Characterization of HMGA2 variants expands the spectrum of Silver-Russell syndrome	29
Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells	29
Human immune phenotyping reveals accelerated aging in type 1 diabetes	29
CCL3 in the bone marrow microenvironment causes bone loss and bone marrow adiposity in aged mice	29
Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time	29
NEXN regulates vascular smooth muscle cell phenotypic switching and neointimal hyperplasia	29
iGATE analysis improves the interpretability of single-cell immune landscape of influenza infection	28
Granzyme B cleaves tenascin-C to release its C-terminal domain in rheumatoid arthritis	28
Chemotherapy delivery time affects treatment outcomes of female patients with diffuse large B cell lymphoma	28
Intravital imaging of peritubular microcirculation impairment in cisplatin-induced acute kidney injury	28
New Pseudomonas infections drive Pf phage transmission in CF airways	28
The administration of exogenous HSP47 as a collagen-specific therapeutic approach	28
Circular RNA Cdr1as inhibits proliferation and delays injury-induced regeneration of the intestinal epithelium	28
CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis	28
The ACTH test fails to diagnose adrenal insufficiency and augments cytokine production in sepsis	28
Combined molnupiravir-nirmatrelvir treatment improves the inhibitory effect on SARS-CoV-2 in macaques	28
Parathyroid hormone 1 receptor signaling mediates breast cancer metastasis to bone in mice	28
A therapeutic HBV vaccine containing a checkpoint modifier enhances CD8+ T cell and antiviral responses	28
SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression	28
A miRNA/CXCR4 signaling axis impairs monopoiesis and angiogenesis in diabetic critical limb ischemia	28
Targeting CDK4 overcomes EMT-mediated tumor heterogeneity and therapeutic resistance in KRAS-mutant lung cancer	28
A Notch/IL-21 signaling axis primes bone marrow T cell progenitor expansion	28
Role of cGAS/STING pathway in aging and sexual dimorphism in diabetic kidney disease	28
ERK hyperactivation in epidermal keratinocytes impairs intercellular adhesion and drives Grover disease pathology	28
Immunosurveillance shapes the emergence of neo-epitope landscapes of sarcomas, revealing prime targets for immunotherapy	28
A peptide blocking the ADORA1-neurabin interaction is anticonvulsant and inhibits epilepsy in an Alzheimer’s model	27
Rapamycin rescues loss of function in blood-brain barrier–interacting Tregs	27
Spheroids as a model for endometriotic lesions	27
Lipid metabolism analysis reveals that DGAT1 regulates Th17 survival by controlling lipid peroxidation in uveitis	27
Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasis	27
Intraperitoneal injection of class A TLR9 agonist enhances anti–PD-1 immunotherapy in colorectal peritoneal metastases	27
Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection	27
Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes	27
Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction	27
AI-assisted discovery of an ethnicity-influenced driver of cell transformation in esophageal and gastroesophageal junction adenocarcinomas	27
Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding	27
Targeting activin receptor–like kinase 7 ameliorates adiposity and associated metabolic disorders	27
Genomic and epigenomic evolution of acquired resistance to combination therapy in esophageal squamous cell carcinoma	27
TNFRSF13B genotypes control immune-mediated pathology by regulating the functions of innate B cells	27
Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model	27
mTORC1 promotes malignant large cell/anaplastic histology and is a targetable vulnerability in SHH-TP53 mutant medulloblastoma	27
Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies against self-antigens	27
Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors	26
ISG15/GRAIL1/CD3 axis influences survival of patients with esophageal adenocarcinoma	26