OOIR: Observatory of International Research

Papers

(The TQCC of Bioengineering & Translational Medicine is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Non‐contact immunological signaling for highly‐efficient regulation of the transcriptional map of human monocytes	227
The effect of local non‐thermal plasma therapy on the cancer‐immunity cycle in a melanoma mouse model	174
An iRGD‐conjugated photothermal therapy‐responsive gold nanoparticle system carrying siCDK7 induces necroptosis and immunotherapeutic responses in lung adenocarcinoma	170
Virtual differential phase‐contrast and dark‐field imaging of x‐ray absorption images via deep learning	115
Blood vessel remodeling in late stage of vascular network reconstruction is essential for peripheral nerve regeneration	87
Advanced strategies to thwart foreign body response to implantable devices	84
TIMP‐1‐expressing breast tumor spheroids for the evaluation of drug penetration and efficacy	72
Injectable hyaluronic acid hydrogels encapsulating drug nanocrystals for long‐term treatment of inflammatory arthritis	72
Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat‐shock protein family	71
Reactive oxygen species‐responsive dual‐targeted nanosystem promoted immunogenic cell death against breast cancer	68
Galactosylated hydroxyl‐polyamidoamine dendrimer targets hepatocytes and improves therapeutic outcomes in a severe model of acetaminophen poisoning‐induced liver failure	66
Role of human dural fibroblasts in the angiogenic responses of human endothelial cells: An in vitro dural model and the application of lab‐on‐a‐chip for EDAS	65
	58
Synergistic ferroptosis‐starvation therapy for bladder cancer based on hyaluronic acid modified metal–organic frameworks	58
Membrane fusogenic nanoparticle‐based HLA‐peptide‐addressing universal T cell receptor‐engineered T (HAUL TCR‐T) cell therapy in solid tumor	55
Rapid, label‐free enrichment of lymphocytes in a closed system using a flow‐through microfluidic device	55
Plasma‐activated medium triggers immunomodulation and autophagic activity for periodontal regeneration	50
Graphene quantum dots‐based targeted nanoprobes detecting drug delivery, imaging, and enhanced chemotherapy of nasopharyngeal carcinoma	47
Sound conditioning strategy promoting paracellular permeability of the blood‐labyrinth‐barrier benefits inner ear drug delivery	47
“Musical dish” efficiently induces osteogenic differentiation of mesenchymal stem cells through music derived microstretch with variable frequency	47
	43
Vascularized lymph node transplantation successfully reverses lymphedema and maintains immunity in a rat lymphedema model	43
Secure reversal of immune evasion from refractory NSCLC and highly contagious CoV‐2 mutants by using 3D‐engineered multifunctional biologics	42
Branched poly‐l‐lysine for cartilage penetrating carriers	39
Engineering of bioactive nanocomplexes on dental floss for targeted gingival therapy	39

Polymorphic nanobody crystals as long‐acting intravitreal therapy for wet age‐related macular degeneration	36
Circular RNA MAP2K2‐modified immunosuppressive dendritic cells for preventing alloimmune rejection in organ transplantation	32
Issue Information	32
Portable hand‐held bioprinters promote in situ tissue regeneration	32
Multimodal near‐infrared molecular imaging of ex vivo endometrial carcinoma via CD47‐based targeted tracer	32
Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood	31
Transcriptional signature in microglia isolated from an Alzheimer's disease mouse model treated with scanning ultrasound	30
Label‐free atherosclerosis diagnosis through a blood drop of apolipoprotein E knockout mouse model using surface‐enhanced Raman spectroscopy validated by machine learning algorithm	30
Mpox disease, diagnosis, and point of care platforms	30
A bioprinted complex tissue model for myotendinous junction with biochemical and biophysical cues	30
Elucidating the role of carrier proteins in cytokine stabilization within double emulsion‐based polymeric nanoparticles	29
Mesenchymal stem cell extracellular vesicle vascularization bioactivity and production yield are responsive to cell culture substrate stiffness	29
Macrophages overexpressing interleukin‐10 target and prevent atherosclerosis: Regression of plaque formation and reduction in necrotic core	29
The potential of low‐intensity pulsed ultrasound to apply the long‐term ovary protection from injury induced by 4‐vinylcyclohexene diepoxide through inhibiting granulosa cell apoptosis	28
Fe‐containing metal–organic framework with D‐penicillamine for cancer‐specific hydrogen peroxide generation and enhanced chemodynamic therapy	28
Cyclophilin A‐mediated mitigation of coronavirus SARS‐CoV‐2	28
Liver‐tumor mimics as a potential translational framework for planning and testing irreversible electroporation with multiple electrodes	27
Developing a new treatment for superficial fungal infection using antifungal Collagen‐HSAF dressing	26
Ex vivo anchored PD‐L1 functionally prevent in vivo renal allograft rejection	26
Targeted brain delivery of RVG29‐modified rifampicin‐loaded nanoparticles for Alzheimer's disease treatment and diagnosis	25
A bioinspired synthetic soft hydrogel for the treatment of dry eye	24
Engineering hypertrophic cartilage grafts from lipoaspirate for critical‐sized calvarial bone defect reconstruction: An adipose tissue‐based developmental engineering approach	24
Microfluidic chip as a promising evaluation method in assisted reproduction: A systematic review	24
Effect of artificial lung fiber bundle geometric design on micro‐ and macro‐scale clot formation	24
Deep learning in precision medicine and focus on glioma	24
	23
Model acetylcholinesterase‐Fc fusion glycoprotein biotechnology system for the manufacture of an organophosphorus toxicant bioscavenging countermeasure	23
Light‐activatable minimally invasive ethyl cellulose ethanol ablation: Biodistribution and potential applications	23
Endothelial‐mesenchymal transition in skeletal muscle: Opportunities and challenges from 3D microphysiological systems	23
Therapeutic potential and impact of nanoengineered patient‐derived mesenchymal stem cells in a murine resection and recurrence model of human glioblastoma	23
Biomaterials and tissue engineering strategies for posterior lamellar eyelid reconstruction: Replacement or regeneration?	22
Silk fibroin and ceramic scaffolds: Comparative in vitro studies for bone regeneration	22
Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space	22
The combination of resveratrol and Bletilla striata polysaccharide decreases inflammatory markers of early osteoarthritis knee and the preliminary results on LPS‐induced OA	22
Simultaneous detection of sepsis host response biomarkers in whole blood using electrochemical biosensor	22
Low‐intensity pulsed ultrasound alleviates doxorubicin‐induced cardiotoxicity via inhibition of S100a8/a9‐mediated cardiac recruitment of neutrophils	22
Tolerability, acceptability, and reproducibility of topical STAR particles in human subjects	21
Hyperelastic, shape‐memorable, and ultra‐cell‐adhesive degradable polycaprolactone‐polyurethane copolymer for tissue regeneration	21
Wearable and battery‐free wound dressing system for wireless and early sepsis diagnosis	21
Plant‐derived exosomes extracted from Lycium barbarum L. loaded with isoliquiritigenin to promote spinal cord injury repair based on 3D printed bionic scaffold	21
Engineering human skin model innervated with itch sensory neuron‐like cells differentiated from induced pluripotent stem cells	20
miRNA‐encapsulated abiotic materials and biovectors for cutaneous and oral wound healing: Biogenesis, mechanisms, and delivery nanocarriers	19
Sprayable tissue adhesive with biodegradation tuned for prevention of postoperative abdominal adhesions	19
Correction to “Activation of NR1H3 attenuates the severity of septic myocardial injury by inhibiting NLRP3 inflammasome”	19
Turning adversity into opportunity: Small extracellular vesicles as nanocarriers for tumor‐associated macrophages re‐education	18
Advances in bioengineered CAR T/NK cell therapy for glioblastoma: Overcoming immunosuppression and nanotechnology‐based strategies for enhanced CAR T/NK cel	18
Improving disease prevention, diagnosis, and treatment using novel bionic technologies	18
Assessing the impact of airborne particulate pollution on human skin utilizing a novel human skin equivalent containing MUTZ‐3‐derived Langerhans cells	18
Immune‐responsive biodegradable scaffolds for enhancing neutrophil regeneration	18
Correction to “Self‐assembly of PEG–PPS polymers and LL‐37 peptide nanomicelles improves the oxidative microenvironment and promotes angiogenesis to facilitate chronic	18

Issue Information	18
Correction to “Drug cross‐linking electrospun fiber for effective infected wound healing”	17
Synergistic drug combination screening using a nanodroplet processing platform to enhance neuroblastoma treatment in TH‐MYCN transgenic mice	17
Synergy of antioxidant and M2 polarization in polyphenol‐modified konjac glucomannan dressing for remodeling wound healing microenvironment	16
In‐cytoplasm mitochondrial transplantation for mesenchymal stem cells engineering and tissue regeneration	16
Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models	16
Polysaccharide‐based biomaterials in a journey from3Dto4Dprinting	16
An ion‐paired moxifloxacin nanosuspension eye drop provides improved prevention and treatment of ocular infection	16
First magnetic particle imaging to assess pulmonary vascular leakage in vivo in the acutely injured and fibrotic lung	15
Carboxymethyl chitosan prolongs adenovirus‐mediated expression of IL‐10 and ameliorates hepatic fibrosis in a mouse model	15
Key parameters for designing robust 2D and 3D spheroid models for in vitro atherosclerosis research	15
Hydrogel viscoelasticity modulates migration and fusion of mesenchymal stem cell spheroids	14
Gellan gum spongy‐like hydrogel‐based dual antibiotic therapy for infected diabetic wounds	14
Insights into the mechanisms, regulation, and therapeutic implications of extracellular matrix stiffness in cancer	14
Integrated bioactive scaffold with aptamer‐targeted stem cell recruitment and growth factor‐induced pro‐differentiation effects for anisotropic meniscal regeneration	14
Self‐assembly of PEG–PPS polymers and LL‐37 peptide nanomicelles improves the oxidative microenvironment and promotes angiogenesis to facilitate chronic wound healing	14
Recent advances in cellular biosensor technology to investigate tau oligomerization	14
Transplantation of bioengineered Reelin‐loadedPLGA/PEGmicelles can accelerate neural tissue regeneration in photothrombotic stroke model of mouse	14
Micro Trojan horses: Engineering extracellular vesicles crossing biological barriers for drug delivery	14
Engineering T cell receptor fusion proteins using nonviral CRISPR/Cas9 genome editing for cancer immunotherapy	14
Photoresponsive prodrug‐dye nanoassembly for in‐situ monitorable cancer therapy	14
Application of nano‐radiosensitizers in combination cancer therapy	14
Hemostats in the clinic	14
A simple urine test by 3D‐plus‐3D immunoassay guides precise in vitro cancer diagnosis	14
Cancer vaccines in the clinic	14
Evaluation of the efficacy and safety of ionic liquids containing ketoconazole in patients with tinea pedis: A randomized controlled clinical trial	14
Temporal profiling of cytokines in passively expressed sweat for detection of infection using wearable device	13
Facile minocycline deployment in gingiva using a dissolvable microneedle patch for the adjunctive treatment of periodontal disease	13
Electrically conductive carbon‐based (bio)‐nanomaterials for cardiac tissue engineering	13
Advances in high throughput cell culture technologies for therapeutic screening and biological discovery applications	13
Fecal microbiota transplantation for the treatment of intestinal and extra‐intestinal diseases: Mechanism basis, clinical application, and potential prospect	13
Tissue‐engineered tracheal implants: Advancements, challenges, and clinical considerations	13
Engineered microvascular basement membrane mimetic for real‐time neutrophil tracking in the microvascular wall	13
REverSe TRanscrIptase chain termination (RESTRICT) for selective measurement of nucleotide analogs used in HIV care and prevention	13
Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls	13
Personalized additive manufacturing of devices for the management of enteroatmospheric fistulas	12
Fibrotic remodeling and tissue regeneration mechanisms define the therapeutic potential of human muscular progenitors	12
An AI‐assisted integrated, scalable, single‐cell phenomic‐transcriptomic platform to elucidate intratumor heterogeneity against immune response	12
	12
Light controlled self‐escape capability of non‐cationic carbon nitride‐based nanosheets in lysosomes for hepatocellular carcinoma targeting stimulus‐responsive gene delivery	12
Issue Information	12
Novel metal peroxide nanoboxes restrain Clostridioides difficile infection beyond the bactericidal and sporicidal activity	12
Hydrophobic ion pairing and microfluidic nanoprecipitation enable efficient nanoformulation of a small molecule indolamine 2, 3‐dioxygenase inhibitor immunotherapeutic	12
Noninvasive monitoring of vascular alterations in mice with acute lower limb ischemia using multimodal photoacoustic imaging	12
Issue Information	12
Evaluation of native and non‐native biomaterials for engineering human skin tissue	12
Formulation‐based approaches for dermal delivery of vaccines and therapeutic nucleic acids: Recent advances and future perspectives	12
Biomimetic nanotherapeutics for targeted drug delivery to glioblastoma multiforme	12
A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays	12
Introduction to Editorial Board Member: Professor Jennifer L. West	12
Cell loaded hydrogel containing Ag‐doped bioactive glass–ceramic nanoparticles as skin substitute: Antibacterial properties, immune response, and scarless cutaneous wound regeneration	12
Electrostatic potential difference between tumor and paratumor regulates cancer stem cell behavior and prognose tumor spread	12
Flourishing tumor organoids: History, emerging technology, and application	12
Monocytes engineered with iSNAP inhibit human B‐lymphoma progression	11
Implantable device actuated by manual button clicks for noninvasive self‐drug administration	11
An injectable gelatin/sericin hydrogel loaded with human umbilical cord mesenchymal stem cells for the treatment of uterine injury	11
Enhancing viability and angiogenic efficacy of mesenchymal stem cells via HSP90α and HSP27 regulation based on ROS stimulation for wound healing	11
Use of FLOSEAL® as a scaffold and its impact on induced neural stem cell phenotype, persistence, and efficacy	11
A novel injectable fibromodulin‐releasing granular hydrogel for tendon healing and functional recovery	11
Potent neutralization of SARS‐CoV‐2 including variants of concern by vaccines presenting the receptor‐binding domain multivalently from nanoscaffolds	11
Pin1/YAP pathway mediates matrix stiffness‐induced epithelial–mesenchymal transition driving cervical cancer metastasis via a non‐Hippo mechanism	11
	11
Advanced technologies for biomedical applications by emerging researchers in Asia‐Pacific	11
A hand‐targeted auxiliary personal protective equipment for intervention of fomite transmission of viruses	11
Activation of NR1H3 attenuates the severity of septic myocardial injury by inhibiting NLRP3 inflammasome	11
	10
	10
A novel platform using homobifunctional hydrazide for enrichment and isolation of urinary circulating RNAs	10
Utilizing induced neural stem cell‐based delivery of a cytokine cocktail to enhance chimeric antigen receptor‐modified T‐cell therapy for brain cancer	10
Next‐generation agents for fluorescence‐guided glioblastoma surgery	10
Microneedles loaded with glutathione‐scavenging composites for nitric oxide enhanced photodynamic therapy of melanoma	10
An engineered niche delineates metastatic potential of breast cancer	10
Stirred culture of cartilaginous microtissues promotes chondrogenic hypertrophy through exposure to intermittent shear stress	10
Transplantation of patient‐specific bile duct bioengineered with chemically reprogrammed and microtopographically differentiated cells	10
Nanomaterials‐based sensors for the detection of COVID‐19: A review	10
Tracking motion kinematics and tremor with intrinsic oscillatory property of instrumental mechanics	10
The BAM‐GelMA‐ADSCs bilayer patch promotes tissue regeneration and functional recovery after large‐area bladder defects in beagles	10
Peptide‐functionalized double network hydrogel with compressible shape memory effect for intervertebral disc regeneration	10