OOIR: Observatory of International Research

Papers

(The TQCC of Bioengineering & Translational Medicine is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Simultaneous detection of sepsis host response biomarkers in whole blood using electrochemical biosensor	231
Polymorphic nanobody crystals as long‐acting intravitreal therapy for wet age‐related macular degeneration	178
Correction to “Self‐assembly of PEG–PPS polymers and LL‐37 peptide nanomicelles improves the oxidative microenvironment and promotes angiogenesis to facilitate chronic	177
Engineering human skin model innervated with itch sensory neuron‐like cells differentiated from induced pluripotent stem cells	117
Liver‐tumor mimics as a potential translational framework for planning and testing irreversible electroporation with multiple electrodes	88
Insights into the mechanisms, regulation, and therapeutic implications of extracellular matrix stiffness in cancer	87
Advanced strategies to thwart foreign body response to implantable devices	81
miRNA‐encapsulated abiotic materials and biovectors for cutaneous and oral wound healing: Biogenesis, mechanisms, and delivery nanocarriers	78
Evaluation of the efficacy and safety of ionic liquids containing ketoconazole in patients with tinea pedis: A randomized controlled clinical trial	74
Fortifying angiogenic efficacy of conditioned media using phototoxic‐free blue light for wound healing	69
Novel metal peroxide nanoboxes restrain Clostridioides difficile infection beyond the bactericidal and sporicidal activity	67
A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays	61
Introduction to Editorial Board Member: Professor Jennifer L. West	60
A soft, bioinspired artificial lymphatic system for interactive ascites transfer	58
4D‐CT deformable image registration using unsupervised recursive cascaded full‐resolution residual networks	57
Stirred culture of cartilaginous microtissues promotes chondrogenic hypertrophy through exposure to intermittent shear stress	52
Light controlled self‐escape capability of non‐cationic carbon nitride‐based nanosheets in lysosomes for hepatocellular carcinoma targeting stimulus‐responsive gene delivery	50
Formulation‐based approaches for dermal delivery of vaccines and therapeutic nucleic acids: Recent advances and future perspectives	47
A polymer‐based systemic hemostat for managing uncontrolled bleeding	47
E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stres	44
Biomimetic nanotherapeutics for targeted drug delivery to glioblastoma multiforme	43
Customized flexible hollow microneedles for psoriasis treatment with reduced‐dose drug	40
Mitomycin C‐immobilized silver nanoparticle‐loaded polycaprolactone membrane for temporary scalp expansion after decompressive craniectomy to prevent wound infection	39
Clathrin light chain‐conjugated drug delivery for cancer	38
Soluble CD80 oral delivery by recombinant Lactococcus suppresses tumor growth by enhancing antitumor immunity	34

Matrix metalloproteinase 2‐responsive dual‐drug‐loaded self‐assembling peptides suppress tumor growth and enhance breast cancer therapy	34
Deep learning‐based multimodal fusion network for segmentation and classification of breast cancers using B‐mode and elastography ultrasound images	33
Tracking metabolic responses based on macronutrient consumption: A comprehensive study to continuously monitor and quantify dual markers (cortisol and glucose) in human sweat using WATCH se	32
Biomedical applications of three‐dimensional bioprinted craniofacial tissue engineering	32
Green/red fluorescent protein disrupting drugs for real‐time permeability tracking in three‐dimensional tumor spheroids	32
BioTM Buzz (Volume 6, Issue 2)	32
Ultrasound‐guided interstitial photothermal therapy generates improved treatment responses in a 9464D model of neuroblastoma	31
An ultralow power wearable vital sign sensor using an electromagnetically reactive near field	31
Fluidic integrated 3D bioprinting system to sustain cell viability towards larynx fabrication	30
Mussel‐inspired biomaterials: From chemistry to clinic	30
Preparation and assessment of an optimized multichannel acellular nerve allograft for peripheral nerve regeneration	30
Feasibility of engineered Bacillus subtilis for use as a microbiome‐based topical drug delivery platform	29
Digital therapeutics in the clinic	29
The emerging role of heart‐on‐a‐chip systems in delineating mechanisms of SARS‐CoV‐2‐induced cardiac dysfunction	29
Issue Information	28
Statistical process monitoring creates a hemodynamic trajectory map after pediatric cardiac surgery: A case study of the arterial switch operation	28
Integrated ATAC‐seq and RNA‐seq analysis identifies key regulatory elements in NK cells activated with feeder cells and IL‐2	28
Biofabricated macrophage and fibroblast membranes synergistically promote skin wound healing	27
Single immunization with an influenza hemagglutinin nanoparticle‐based vaccine elicits durable protective immunity	27
Multimodal nanoparticle‐containing modified suberoylanilide hydroxamic acid polymer conjugates to mitigate immune dysfunction in severe inflammation	27
Correction to “A stretchable, electroconductive tissue adhesive for the treatment of neural injury”	26
Rare earth smart nanomaterials for bone tissue engineering and implantology: Advances, challenges, and prospects	26
Biomembrane‐coated nanosystems as next‐generation delivery systems for the treatment of gastrointestinal cancers	26
Injectable bioactive glass/sodium alginate hydrogel with immunomodulatory and angiogenic properties for enhanced tendon healing	25
Machine learning‐assisted point‐of‐care diagnostics for cardiovascular healthcare	25
Chitosan‐based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy	25
Issue Information	24
Issue Information	24
Macrophage‐based delivery of anti‐fibrotic proteins alleviates bleomycin‐induced pulmonary fibrosis in mice	24
A digital pathology tool for quantification of color features in histologic specimens	24
Pluronic F127 “nanoarmor” for stabilization of Cowpea mosaic virus immunotherapy	24
Dissolved gases from pressure changes in the lungs elicit an immune response in human peripheral blood	23
Leadership transition	23
A stretchable, electroconductive tissue adhesive for the treatment of neural injury	23
Preclinical study of peripheral nerve regeneration using nerve guidance conduits based on polyhydroxyalkanaotes	22
Modulating neuroinflammation through molecular, cellular and biomaterial‐based approaches to treat spinal cord injury	22
Macromolecular nanoparticles to attenuate both reactive oxygen species and inflammatory damage for treating Alzheimer's disease	22
Wearable biosensors for human fatigue diagnosis: A review	22
Pediatric pulmonary valve replacements: Clinical challenges and emerging technologies	21
Synergistic combination therapy delivered via layer‐by‐layer nanoparticles induces solid tumor regression of ovarian cancer	21
Polylysine for skin regeneration: A review of recent advances and future perspectives	21
Cold air plasma improving rheumatoid arthritis via mitochondrial apoptosis pathway	21
Lipid‐based regulators of immunity	21
Long‐acting and extended‐release implant and nanoformulations with a synergistic antiretroviral two‐drug combination controls HIV‐1 infection in a humanized mouse model	21
Issue Information	20
Photobiomodulation improves functional recovery after mild traumatic brain injury	20
Transplantation of neuron‐inducing grafts embedding positively charged gold nanoparticles for the treatment of spinal cord injury	19
Cardiovascular patches applied in congenital cardiac surgery: Current materials and prospects	19
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Combined use of microbubbles of various sizes and single‐transducer dual‐frequency ultrasound for safe and efficient inner ear drug delivery	19

ε‐poly‐L‐lysine‐modified polydopamine nanoparticles for targeted photothermal therapy of drug‐resistant bacterial keratitis	18
Magnetic nanoparticles enhance the cellular immune response of dendritic cell tumor vaccines by realizing the cytoplasmic delivery of tumor antigens	18
Machine learning‐directed electrical impedance tomography to predict metabolically vulnerable plaques	18
Antibody drug conjugates in the clinic	18
Synchronously in vivo real‐time monitoring bacterial load and temperature with evaluating immune response to decipher bacterial infection	18
High‐dose vitamin D metabolite delivery inhibits breast cancer metastasis	17
Three‐dimensional morphological revealing of human placental villi with common obstetric complications via optical coherence tomography	17
Targeting the epigenome with advanced delivery strategies for epigenetic modulators	17
“Guide” of muscone modification enhanced brain‐targeting efficacy and anti‐glioma effect of lactoferrin modified DTX liposomes	17
Deep learning in precision medicine and focus on glioma	17
Sensor‐integrated brain‐on‐a‐chip platforms: Improving the predictive validity in neurodegenerative research	17
Rapid, label‐free enrichment of lymphocytes in a closed system using a flow‐through microfluidic device	17
Developing a new treatment for superficial fungal infection using antifungal Collagen‐HSAF dressing	16
Synergistic drug combination screening using a nanodroplet processing platform to enhance neuroblastoma treatment in TH‐MYCN transgenic mice	16
Macrophages overexpressing interleukin‐10 target and prevent atherosclerosis: Regression of plaque formation and reduction in necrotic core	16
Hyperelastic, shape‐memorable, and ultra‐cell‐adhesive degradable polycaprolactone‐polyurethane copolymer for tissue regeneration	16
The combination of resveratrol and Bletilla striata polysaccharide decreases inflammatory markers of early osteoarthritis knee and the preliminary results on LPS‐induced OA	16
Elucidating the role of carrier proteins in cytokine stabilization within double emulsion‐based polymeric nanoparticles	16
Transplantation of bioengineered Reelin‐loadedPLGA/PEGmicelles can accelerate neural tissue regeneration in photothrombotic stroke model of mouse	16
Issue Information	16
Radiation nanosensitizers in cancer therapy—From preclinical discoveries to the outcomes of early clinical trials	15
Nanoparticle contrast‐enhanced computed tomography and magnetic resonance imaging of vascularization of a subcutaneous niche for islet transplantation	15
Portable hand‐held bioprinters promote in situ tissue regeneration	15
Injectable hyaluronic acid hydrogels encapsulating drug nanocrystals for long‐term treatment of inflammatory arthritis	15
An injectable gelatin/sericin hydrogel loaded with human umbilical cord mesenchymal stem cells for the treatment of uterine injury	15
Utilizing induced neural stem cell‐based delivery of a cytokine cocktail to enhance chimeric antigen receptor‐modified T‐cell therapy for brain cancer	15
Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat‐shock protein family	15
Gellan gum spongy‐like hydrogel‐based dual antibiotic therapy for infected diabetic wounds	15
Advanced technologies for biomedical applications by emerging researchers in Asia‐Pacific	15
Advances in high throughput cell culture technologies for therapeutic screening and biological discovery applications	15
Galactosylated hydroxyl‐polyamidoamine dendrimer targets hepatocytes and improves therapeutic outcomes in a severe model of acetaminophen poisoning‐induced liver failure	15
Needle to needle robot‐assisted manufacture of cell therapy products	14
Fecal microbiota transplantation for the treatment of intestinal and extra‐intestinal diseases: Mechanism basis, clinical application, and potential prospect	14
In vivo immunogenicity assessment of a multiepitope‐displayed phage vaccine against Brucella species infection in BALB/c mice	14
Facile minocycline deployment in gingiva using a dissolvable microneedle patch for the adjunctive treatment of periodontal disease	14
Microneedles loaded with glutathione‐scavenging composites for nitric oxide enhanced photodynamic therapy of melanoma	14
Macrophage‐targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis	14
Bilayer 3D co‐culture platform inducing the differentiation of normal fibroblasts into cancer‐associated fibroblast like cells: New in vitro source to obtain cancer‐associated fibroblasts	14
Thermosensitive hydrogel‐based GPR124 delivery strategy for rebuilding blood‐spinal cord barrier	14
Adipose‐derived stem cells enriched with therapeutic mRNA TGF‐β3 and IL‐10 synergistically promote scar‐less wound healing in preclinical models	14
In vivo evaluation of decellularized skeletal muscle matrices for skeletal muscle repair: A systematic review	13
Enabling next‐generation therapies: A foreword to a special issue on nanotechnology in medicine	13
Diagnosis of pregnancy disorder in the first‐trimester patient plasma with Raman spectroscopy and protein analysis	13
Automated microarray platform for single‐cell sorting and collection of lymphocytes following HIV reactivation	13
Mesenchymal stem cells paracrine proteins from three‐dimensional dynamic culture system promoted wound healing in third‐degree burn models	13
Nanorod/nanodisk‐integrated liquid crystalline systems for starvation, chemodynamic, and photothermal therapy of cancer	13
Eye of the future: Unlocking the potential utilization of hydrogels in intraocular lenses	13
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Nanoporous electroporation needle for localized intracellular delivery in deep tissues	13
SHEAR saliva collection device augments sample properties for improved analytical performance	12
Systemic administration of dendrimer N‐acetyl cysteine improves outcomes and survival following cardiac arrest	12
Corroded iron stent increases fibrin deposition and promotes endothelialization after stenting	12
Anterior substitutional urethroplasty using a biomimetic poly‐l‐lactide nanofiber membrane: Preclinical and clinical outcomes	12
Engineering a conduction‐consistent cardiac patch with graphene oxide modified butterfly wings and human pluripotent stem cell‐derived cardiomyocytes	12
Issue Information	12
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A double‐edged sword: The complex interplay between engineered nanoparticles and platelets	12
Unleashing the potential of mRNA: Overcoming delivery challenges with nanoparticles	12
3D bioprinting of an implantable xeno‐free vascularized human skin graft	12
The novel hyaluronic acid granular hydrogel attenuates osteoarthritis progression by inhibiting the TLR‐2/NF‐κB signaling pathway through suppressing cellular senescence	12
Light‐controlled scaffold‐ and serum‐free hard palatal‐derived mesenchymal stem cell aggregates for bone regeneration	12
Engineering pedicled vascularized bladder tissue for functional bladder defect repair	12
Multifunctional electrospun asymmetric wettable membrane containing black phosphorus/Rg1 for enhancing infected wound healing	12
Fluid mechanical performance of ureteral stents: The role of side hole and lumen size	12
Spinal cord tissue engineering using human primary neural progenitor cells and astrocytes	12
Use of patient‐derived tumor organoid platform to predict the benefit of postoperative adjuvant chemotherapy for poor responders to neoadjuvant chemoradiotherapy in locally advanced rectal cancer	12
Atomic force spectroscopy‐based essay to evaluate oocyte postovulatory aging	12
Assessing the impact of long‐term storage on the quality and integrity of biological specimens in a reproductive biobank	12
Chitosan nanofiber biocomposites for potential wound healing applications: Antioxidant activity with synergic antibacterial effect	11
Issue Information	11
Propionate‐producing engineered probiotics ameliorated murine ulcerative colitis by restoring anti‐inflammatory macrophage via the GPR43/HDAC1/IL‐10 axis	11
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Brain‐targeted exosome‐mimetic cell membrane nanovesicles with therapeutic oligonucleotides elicit anti‐tumor effects in glioblastoma animal models	11
Static magnetic field assisted thawing improves cryopreservation of mouse whole ovaries	11
Rational design of structure‐based vaccines targeting misfolded alpha‐synuclein conformers of Parkinson's disease and related disorders	11
Integrated role of human thymic stromal cells in hematopoietic stem cell extravasation	11
Optimization of ionizable lipids for aerosolizable mRNA lipid nanoparticles	11
Machine learning‐based SERS serum detection platform for high‐sensitive and high‐throughput diagnosis of colorectal precancerous lesions	11
Vascular stiffening in aging females with a hypertension‐induced HIF2A gain‐of‐function mutation	11
Establishing a scalable perfusion strategy for the manufacture of CAR‐T cells in stirred‐tank bioreactors using a quality‐by‐design approach	11