OOIR: Observatory of International Research

Papers

(The TQCC of Open Chemistry is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Cynarin inhibits PDGF-BB-induced proliferation and activation in hepatic stellate cells through PPARγ	57
Impact of benzimidazole functional groups on the n-doping properties of benzimidazole derivatives	57
Treatment of gestational diabetes by Acroptilon repens leaf aqueous extract green-formulated iron nanoparticles in rats	54
Molecular docking analysis of subtilisin-like alkaline serine protease (SLASP) and laccase with natural biopolymers	52
Cytotoxic ketosteroids from the Red Sea soft coral Dendronephthya sp.	45
Analysis of bioactive compounds present in Boerhavia elegans seeds by GC-MS	37
Phytochemical study, antioxidant activity, and dermoprotective activity of Chenopodium ambrosioides (L.)	37
Biosynthesis of Ag/Cu nanocomposite mediated by Curcuma longa: Evaluation of its antibacterial properties against oral pathogens	36
Phytochemical profiling and bioactivity evaluation of CBD- and THC-enriched Cannabis sativa extracts: In vitro and in silico investigation of antioxidant and anti-inflammatory eff	33
Cold-acclimation effect on cadmium absorption and biosynthesis of polyphenolics, and free proline and photosynthetic pigments in Spirogyra aequinoctialis	28
Thymbra spicataleaf extract driven biogenic synthesis of Au/Fe₃O₄nanocomposite and its bio-application in the treatment of different types of leukemia	26
Anti-OTC antibody-conjugated fluorescent magnetic/silica and fluorescent hybrid silica nanoparticles for oxytetracycline detection	25
Screening and optimization of extracellular pectinase produced by Bacillus thuringiensis SH7	22
Does Erodium trifolium (Cav.) Guitt exhibit medicinal properties? Response elements from phytochemical profiling, enzyme-inhibiting, and antioxidant and antimicrobial activities	21
Ultrasonic-induced reversible blood–brain barrier opening: Safety evaluation into the cellular level	20
Structural, physical, and mechanical properties of the TiO₂ added hydroxyapatite composites	20
Treatment of rat brain ischemia model by NSCs-polymer scaffold transplantation	19
Optimization of polyphenol extraction, phenolic profile by LC-ESI-MS/MS, antioxidant, anti-enzymatic, and cytotoxic activities of Physalis acutifolia	19
Photocatalytic degradation of Rhodamine B in aqueous phase by bimetallic metal-organic framework M/Fe-MOF (M = Co, Cu, and Mg)	18
Iron indices and hemogram in renal anemia and the improvement with Tribulus terrestris green-formulated silver nanoparticles applied on rat model	17
Coagulation activity of liquid extraction of Leucaena leucocephala and Sesbania grandiflora on the removal of turbidity	17
Synthesis and characterization of antioxidant-enriched Moringa oil-based edible oleogel	16
Model predictive control for precision irrigation of a Quinoa crop	16
Cannabis sativa L. essential oil: Chemical composition, anti-oxidant, anti-microbial properties, and acute toxicity: In vitro, in vivo, and in silico study	16
Protective effects of asperuloside against cyclophosphamide-induced urotoxicity and hematotoxicity in rats	14

Efficiency analysis of photovoltaic systems installed in different geographical locations	14
Mechanical property evaluation of tellurite–germanate glasses and comparison of their radiation-shielding characteristics using EPICS2017 to other glass systems	14
Inductively coupled plasma mass spectrometry assessment of essential and toxic trace elements in traditional spices consumed by the population of the Middle Eastern region in their recipes	13
Effects of nanoparticles on the activity and resistance genes of anaerobic digestion enzymes in livestock and poultry manure containing the antibiotic tetracycline	13
Effect of pumpkin enriched with calcium lactate on iron status in an animal model of postmenopausal osteoporosis	13
Effect of copper nanoparticles green-synthesized using Ocimum basilicum against Pseudomonas aeruginosa in mice lung infection model	13
Determination of polyphenols in Chinese jujube using ultra-performance liquid chromatography–mass spectrometry	12
Exploring the phytochemical profile and antioxidant evaluation: Molecular docking and ADMET analysis of main compounds from three Solanum species in Saudi Arabia	12
Theoretical investigations on the excited-state intramolecular proton transfer in the solvated 2-hydroxy-1-naphthaldehyde carbohydrazone	11
Study on the influence of physical interlayers on the remaining oil production under different development modes	11
Cytotoxic activity of guaiane-type sesquiterpene lactone (deoxycynaropicrin) isolated from the leaves of Centaurothamnus maximus	11
Mechanical and gamma-ray shielding examinations of Bi₂O₃–PbO–CdO–B₂O₃ glass system	11
A case study on the influence of soil amendment on ginger oil’s physicochemical properties, mineral contents, microbial load, and HPLC determination of its vitamin level	10
Characterization and ecological risk assessment of toxic metals in mangrove sediments near Langen Village in Tieshan Bay of Beibu Gulf, China	10
Physicochemical components, antioxidant activity, and predictive models for quality of soursop tea (Annona muricata L.) during heat pump drying	10
Mechanism study of Cordyceps sinensis alleviates renal ischemia–reperfusion injury	10
Comparative analysis of fruit quality parameters and volatile compounds in commercially grown citrus cultivars	10
Performance analyses of detonation engine cogeneration cycles	10
Surfactant evaluation for enhanced oil recovery: Phase behavior and interfacial tension	10
Antioxidant, sensory, and functional properties of low-alcoholic IPA beer with Pinus sylvestris L. shoots addition fermented using unconventional yeast	10
A comparative study of the antifungal efficacy and phytochemical composition of date palm leaflet extracts	10
Chemical compositions of Litsea umbellata and inhibition activities	9
Rapeseed oil-based hippurate amide nanocomposite coating material for anticorrosive and antibacterial applications	9
The impact of chemical modifications on gamma-ray attenuation properties of some WO₃-reinforced tellurite glasses	9
Unveiling the molecular composition and biological properties of essential oil derived from the leaves of wild Mentha aquatica L.: A comprehensive in vitro and in silico explorati	9
Deformation behavior and formability of friction stir processed DP600 steel	9
Assessment of potentially toxic elements and health risks of agricultural soil in Southwest Riyadh, Saudi Arabia	9
Two triazole-based coordination polymers: Synthesis and crystal structure characterization	9
In vitro exploration of Hypsizygus ulmarius (Bull.) mushroom fruiting bodies: Potential antidiabetic and anti-inflammatory agent	9
In vivo protective effects of vitamin C against cyto-genotoxicity induced by Dysphania ambrosioides aqueous extract	9
Computational study of ADME-Tox prediction of selected phytochemicals from Punica granatum peels	8
Heavy metals in road dust from typical old industrial areas of Wuhan: Seasonal distribution and bioaccessibility-based health risk assessment	8
X-ray shielding properties of bismuth-borate glass doped with rare earth ions	8
(1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl 4-amino-3-phenylbutanoate hydrochloride: Synthesis and anticonvulsant activity	8
Bioactive triterpenoids from Indonesian medicinal plant Syzygium aqueum	8
Integrated geophysical techniques applied for petroleum basins structural characterization in the central part of the Western Desert, Egypt	8
Phytochemical analysis of Ziziphus jujube leaf at different foliar ages based on widely targeted metabolomics	8
New plant resistance inducers based on polyamines	8
A detailed investigation on highly dense CuZr bulk metallic glasses for shielding purposes	8
Investigating the adsorption mechanism of zinc chloride-modified porous carbon for sulfadiazine removal from water	8
Antihyperglycemic, antiglycation, anti-hypercholesteremic, and toxicity evaluation with gas chromatography mass spectrometry profiling for Aloe armatissima leaves	8
Investigation of improved optical and conductivity properties of poly(methyl methacrylate)–MXenes (PMMA–MXenes) nanocomposite thin films for optoelectronic applications	7
The comparison of gold extraction methods from the rock using thiourea and thiosulfate	7
Curcumin conjugated zinc nanoparticles for the treatment of myocardial infarction	7
Aconitum coreanum Rapaics: Botany, traditional uses, phytochemistry, pharmacology, and toxicology	7
Evaluation of second trimester plasma lipoxin A4, VEGFR-1, IL-6, and TNF-α levels in pregnant women with gestational diabetes mellitus	7
Extraction and characterization of type I collagen from scales of Mexican Biajaiba fish	7
Larvicidal properties of essential oils of three Artemisia species against the chemically insecticide-resistant Nile fever vector Culex pipiens (L.) (Diptera: Culicidae): In vitro	7
Structural, physical, and radiation absorption properties of a significant nuclear power plant component: A comparison between REX-734 and 316L SS austenitic stainless steels	7
A study to investigate the anticancer potential of carvacrol via targeting Notch signaling in breast cancer	7

The role of passage numbers of donor cells in the development of Arabian Oryx – Cow interspecific somatic cell nuclear transfer embryos	7
Black mulberry (Morus nigra L.) fruits: As a medicinal plant rich in human health-promoting compounds	7
Integrated track of nano-informatics coupling with the enrichment concept in developing a novel nanoparticle targeting ERK protein in Naegleria fowleri	7
Porous silicon nanostructures: Synthesis, characterization, and their antifungal activity	7
Physicochemical and biological properties of carvacrol	7
Antimicrobial activity, induction of ROS generation in HepG2 liver cancer cells, and chemical composition of Pterospermum heterophyllum	7
Effect of gamma rays irradiation in the structure, optical, and electrical properties of samarium doped bismuth titanate ceramics	7
The abrogative effect of propolis on acrylamide-induced toxicity in male albino rats: Histological study	7
Treatment of gastric cancer by green mediated silver nanoparticles using Pistacia atlantica bark aqueous extract	7
Antioxidant and antidiabetic potentials of methoxy-substituted Schiff bases using in vitro, in vivo, and molecular simulation approaches	6
Experimental study on photocatalytic CO₂ reduction performance of ZnS/CdS-TiO₂ nanotube array thin films	6
Anti-parasitic activity and computational studies on a novel labdane diterpene from the roots of Vachellia nilotica	6
Essential oils from Brazilian plants: A literature analysis of anti-inflammatory and antimalarial properties and in silico validation	6
Integrative in silico evaluation of the antiviral potential of terpenoids and its metal complexes derived from Homalomena aromatica based on main protease of SARS-CoV-2	6
Estimating molecular properties, drug-likeness, cardiotoxic risk, liability profile, and molecular docking study to characterize binding process of key phyto-compounds against serotonin 5-HT2A recepto	6
Corrigendum to “Aroma components of tobacco powder from different producing areas based on gas chromatography ion mobility spectrometry”	6
Evaluation of the impact of music on antioxidant mechanisms and survival in salt-stressed goldfish	6
Green synthesis of ZIF-8 for selective adsorption of dyes in water purification	6
NaCl regulates goldfish growth and survival at three food supply levels under hypoxia	6
Energy consumption, mechanical and metallographic properties of cryogenically treated tool steels	6
Investigating the impact of CO₂emissions on the COVID-19 pandemic by generalized linear mixed model approach with inverse Gaussian and gamma distributions	6
Phytochemical and pharmacological profiling ofTrewia nudifloraLinn. leaf extract deciphers therapeutic potentials against thrombosis, arthritis, helminths, and insects	6
Flexural strength and thermal properties of carbon black nanoparticle reinforced epoxy composites obtained from waste tires	6
Investigating the effect of resveratrol on apoptosis and regulation of gene expression of Caco-2 cells: Unravelling potential implications for colorectal cancer treatment	6
Clay-based bricks’ rich illite mineral for gamma-ray shielding applications: An experimental evaluation of the effect of pressure rates on gamma-ray attenuation parameters	6
Metformin inhibits knee osteoarthritis induced by type 2 diabetes mellitus in rats: S100A8/9 and S100A12 as players and therapeutic targets	6
Synthesis of new analogs of N-substituted(benzoylamino)-1,2,3,6-tetrahydropyridines	6
Effects of green decorated AgNPs on lignin-modified magnetic nanoparticles mediated by Cydonia on cecal ligation and puncture-induced sepsis	6
Antifungal–antiproliferative norcycloartane-type triterpenes from the Red Sea green alga Tydemania expeditionis	6
An alternative approach for the excess lifetime cancer risk and prediction of radiological parameters	6
Retraction of “Two mixed-ligand coordination polymers based on 2,5-thiophenedicarboxylic acid and flexible N-donor ligands: The protective effect on periodontitis via reducing the release of IL-1β and	6
Phytochemical constituents, in vitro antibacterial activity, and computational studies of Sudanese Musa acuminate Colla fruit peel hydro-ethanol extract	6
Electrochemical dissolution of titanium under alternating current polarization to obtain its dioxide	6
Specialized compounds of four Cameroonian spices: Isolation, characterization, and in silico evaluation as prospective SARS-CoV-2 inhibitors	6
Role and mechanism of fruit waste polyphenols in diabetes management	6
Cyclic connectivity index of bipolar fuzzy incidence graph	5
Computational design and in vitro assay of lantadene-based novel inhibitors of NS3 protease of dengue virus	5
Simulation of a reactor considering the Stamicarbon, Snamprogetti, and Toyo patents for obtaining urea	5
An automated reading of semi-quantitative hemagglutination results in microplates: Micro-assay for plant lectins	5
Evaluating polyphenol and ascorbic acid contents, tannin removal ability, and physical properties during hydrolysis and convective hot-air drying of cashew apple powder	5
Biosurfactants in biocorrosion and corrosion mitigation of metals: An overview	5
Evaluation and chemical characterization of bioactive secondary metabolites from endophytic fungi associated with the ethnomedicinal plantBergenia ciliata	5
Influence of the addition of WO₃ on TeO₂–Na₂O glass systems in view of the feature of mechanical, optical, and photon attenuation	5
Bioactivity of a polyhydroxy gorgostane steroid from Xenia umbellata	5
Integrating network pharmacology and molecular docking to explore the potential mechanism of Xinguan No. 3 in the treatment of COVID-19	5
Anthocyanin extract from black rice attenuates chronic inflammation in DSS-induced colitis mouse model by modulating the gut microbiota	5
Valorization of Juglans regia L. (Walnut) green husk from Jordan: Analysis of fatty acids, phenolics, antioxidant, and cytotoxic activities	5
Twofold interpenetrated 3D Cd(ii) complex: Crystal structure and luminescent property	5
Bordeaux mixture accelerates ripening, delays senescence, and promotes metabolite accumulation in jujube fruit	5
Studies on the chemical composition of plants used in traditional medicine in Congo	5
BiCAM-based automated scoring system for digital logic circuit diagrams	5
Synthesis of multi-template molecularly imprinted polymers (MT-MIPs) for isolating ethyl para-methoxycinnamate and ethyl cinnamate from Kaempferia galanga L., extract with methacrylic acid as f	5
Environmental impact assesment regulation applications and their analysis in Turkey	5
Investigation of mechanical activation effect on high-volume natural pozzolanic cements	5
Green synthesis, characterization of silver nanoparticles using Rhynchosia capitata leaf extract and their biological activities	5
Gamma-ray shielding properties of Nd₂O₃-added iron–boron–phosphate-based composites	5
Microwave and Cs⁺-assisted chemo selective reaction protocol for synthesizing 2-styryl quinoline biorelevant molecules	5
Exploring anticancer activity of the Indonesian guava leaf (Psidium guajavaL.) fraction on various human cancer cell lines in anin vitrocell-based approach	5
Green synthesis of silver nanoparticles from Olea europaea L. extracted polysaccharides, characterization, and its assessment as an antimicrobial agent against multiple pathogenic microbes	5
Nitrogen and boron co-doped carbon dots probe for selectively detecting Hg²⁺ in water samples and the detection mechanism	5
Quality control analyses of selected honey samples from Serbia based on their mineral and flavonoid profiles, and the invertase activity	5
The impact of drying and extraction methods on total lipid, fatty acid profile, and cytotoxicity of Tenebrio molitor larvae	5