OOIR: Observatory of International Research

Papers

(The H4-Index of npj Precision Oncology is 48. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
KMT2C inactivation leads to PTEN downregulation and tolerance to DNA damage during cell cycle progression	530
Circulating tumor DNA in ALK-positive anaplastic large cell lymphoma: a proof-of-concept study	279
Exosome- transported FER inhibitor suppresses progression of diffuse large B-cell lymphoma via regulating AJUBA/Hippo axis	214
BRAF v600E–mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study	187
AI-enabled single-cell dissection of the palmitoylation landscape identifies a multicellular prognostic program in gastric cancer	175
Author Correction: An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study	163
Therapeutic responses in patients with advanced NSCLC enrolled in early-phase clinical trials at MD Anderson	159
Single nuclei and spatial profiling of sacrococcygeal teratomas reveals cellular composition and X inactivation heterogeneity	145
Benchmarking progression-free survival ratio as primary endpoint in precision oncology clinical trials	142
Deciphering brain metastasis in epithelial ovarian cancer: multimodal analysis and potential biomarkers	116
Evolving landscape of targeted immunotherapeutic interventions and CAR-T therapy for acute myeloid leukemia	116
Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies	110
Development and testing of a polygenic risk score for breast cancer aggressiveness	101
Multi-modal characterization of metabolic and immune gene clusters in adrenocortical carcinoma treatment	92
Robust multicentre detection and classification of colorectal liver metastases on CT: application of foundation models	87
Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning	85
High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer	81
Endoplasmic reticulum stress in brain metastatic cascade	81
Interferon signaling and ferroptosis in tumor immunology and therapy	80
MYSM1 promotes lung adenocarcinoma progression via TRAF2/3-mediated activation of MAPK and non-canonical NF-κB pathways	79
Comprehensive multi-omics analysis identifies cancer subtypes and prognostic signatures of hepatitis B virus-associated hepatocellular carcinoma	78
Inferring translational efficiency from transcriptomes improves noncanonical neoantigen prioritization and cancer patient stratification	75
An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study	73
Sub-regional radiomics combining multichannel 2-dimensional or 3-dimensional deep learning for predicting neoadjuvant chemo-immunotherapy response in esophageal squamous cell carcinoma: a multicenter	73
A protein-encoding CCDC7 circular RNA inhibits the progression of prostate cancer by up-regulating FLRT3	73

Grading of lung adenocarcinomas with simultaneous segmentation by artificial intelligence (GLASS-AI)	72
Development of a translational murine model for antibody-drug conjugate-induced interstitial lung disease	70
Co-targeting KRAS G12C and EGFR reduces both mutant and wild-type RAS-GTP	69
The dynamic immune behavior of primary and metastatic ovarian carcinoma	68
Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers	67
Constitutional mismatch repair deficiency mimicking Lynch syndrome is associated with hypomorphic mismatch repair gene variants	67
Developing survival prediction models in colorectal cancer using epigenome-wide DNA methylation data from whole blood	65
Artificial intelligence-driven prediction of lymph node metastasis in T1 esophageal squamous cell carcinoma using whole slide images	64
Spatial transcriptomics reveals molecular heterogeneity and subtype-specific therapeutic targets in small cell lung cancer	64
Genome-wide analyses reveals an association between invasive urothelial carcinoma in the Shetland sheepdog and NIPAL1	61
Mucin-1: a promising pan-cancer therapeutic target	59
Complement activation in tumor microenvironment after neoadjuvant therapy and its impact on pancreatic cancer outcomes	59
A perspective on life-cycle health technology assessment and real-world evidence for precision oncology in Canada	59
Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates	56
Barriers and opportunities in pancreatic cancer immunotherapy	54
A multi-center study on the consistency of drug sensitivity testing in patients with acute myeloid leukemia	52
Analyses of canine cancer mutations and treatment outcomes using real-world clinico-genomics data of 2119 dogs	51
Prospective implementation of an aqueous humor liquid biopsy platform informs clinical diagnosis and management of retinoblastoma and other intraocular lesions	51
User-centered design approach to visualize PROMs for molecular tumor boards	50
Pan-cancer molecular tumor board experience with biomarker-driven precision immunotherapy	50
AI-driven body composition atlas reveals its association with NSCLC immunotherapy outcome and molecular background: a multicenter study	48
Prolonged response to dual immune checkpoint blockade in patients with advanced solid tumors: a case series	48
Single-cell analysis identifies dysregulated cell type-specific gene programs and intercellular crosstalk underlying colorectal cancer	48