npj Digital Medicine

Article	Citations
AI-based skin cancer detection: the balance between access and overutilization	687
A hybrid machine learning approach for the personalized prognostication of aggressive skin cancers	634
Addressing racial disparities in surgical care with machine learning	457
Seasonal timing and interindividual differences in shiftwork adaptation	449
Negative control-calibrated difference-in-difference analyses: addressing unmeasured confounding in RWD with application to racial/ethnic differences	394
Watching Parkinson’s disease with wrist-based sensors	382
Continuous monitoring of surgical bimanual expertise using deep neural networks in virtual reality simulation	360
TIMER: temporal instruction modeling and evaluation for longitudinal clinical records	355
Predicting 1-year successful clinical use of an arteriovenous access for hemodialysis using machine learning	336
Metabolomic characterization of frailty identifies subtype-specific management strategies	303
Computational strategic recruitment for representation and coverage studied in the All of Us Research Program	300
Author Correction: Self-supervised learning of accelerometer data provides new insights for sleep and its association with mortality	279
Promoting racial equity in digital health: applying a cross-disciplinary equity framework	273
Interpretable Multiomics Models for Predicting Surgical Interventions and Blood Transfusion Requirements in Traumatic Brain Injury	261
Large language models-enabled digital twins for precision medicine in rare gynecological tumors	257
Generalized multi task learning framework for glucose forecasting and hypoglycemia detection using simulation to reality	254
Machine learning-based forecasting of daily acute ischemic stroke admissions using weather data	251
Evaluating human-in-the-loop strategies for artificial intelligence-enabled translation of patient discharge instructions: a multidisciplinary analysis	246
A comparison of self-reported COVID-19 symptoms between android and iOS CoronaCheck app users	240
Reasoning red teaming in healthcare not all paths to a desired outcome are desirable	239
A randomized trial of a mobile health intervention to augment cardiac rehabilitation	225
An automated COVID-19 triage pipeline using artificial intelligence based on chest radiographs and clinical data	217
Machine learning model for differentiating xanthogranulomatous cholecystitis and gallbladder cancer in multicenter largescale study	210
Multimodal analysis of whole slide images in colorectal cancer	210
Breaking geographic and language barriers in neuropsychology: online administration of MoCA in diverse populations	194

Patient agency and large language models in worldwide encoding of equity	191
AI-driven virtual cell models in preclinical research: technical pathways, validation mechanisms, and clinical translation potential	189
Validation of Amazon Halo Movement: a smartphone camera-based assessment of movement health	186
A Representation Fusion Framework for Decoupling Diagnostic Information in Multimodal Learning	182
India’s evolving digital health strategy	177
Systematic review to understand users perspectives on AI-enabled decision aids to inform shared decision making	171
Prognostic model and U-shaped SBP-risk correlation in unstable pelvic fractures with TBI	170
Incorporating large language models as clinical decision support in oncology: the Woollie model	165
Challenges and recommendations for enhancing digital data protection in Indian Medical Research and Healthcare Sector	158
Establishing organizational AI governance in healthcare: a case study in Canada	154
Defining digital surgery for the future	149
Unobtrusive inference of diurnal rhythms from smartphone data	149
Policy brief: ambient AI scribes and the coding arms race	138
Situating governance and regulatory concerns for generative artificial intelligence and large language models in medical education	136
Clinically meaningful interpretability of an AI model for ECG classification	135
Whole slide image based deep learning refines prognosis and therapeutic response evaluation in lung adenocarcinoma	133
Clinical usefulness of digital twin guided virtual amiodarone test in patients with atrial fibrillation ablation	128
Will AI become our Co-PI?	127
Why we should not mistake accuracy of medical AI for efficiency	124
Effectiveness of automated alerting system compared to usual care for the management of sepsis	123
Dose–response relationship between computerized cognitive training and cognitive improvement	121
Early adverse physiological event detection using commercial wearables: challenges and opportunities	116
An adversarial training framework for mitigating algorithmic biases in clinical machine learning	116
Next-generation AI framework for comprehensive oral leukoplakia evaluation and management	110
Effectiveness of gamified team competition as mHealth intervention for medical interns: a cluster micro-randomized trial	108
Deploying digital health tools within large, complex health systems: key considerations for adoption and implementation	106
Machine learning on interictal intracranial EEG predicts surgical outcome in drug resistant epilepsy	105
Scoping review of deep learning research illuminates artificial intelligence chasm in otolaryngology-head and neck surgery	103
Computational network models for forecasting and control of mental health trajectories in digital applications	99
Small language models learn enhanced reasoning skills from medical textbooks	97
Prevalence and course of pregnancy symptoms using self-reported pregnancy app symptom tracker data	95
The impact of inconsistent human annotations on AI driven clinical decision making	94
A scoping review of reporting gaps in FDA-approved AI medical devices	92
Impact of missing electronic fetal monitoring signals on perinatal asphyxia: a multicohort analysis	91
Evaluating evidence-based health information from generative AI using a cross-sectional study with laypeople seeking screening information	91
Predicting outcomes following endovascular aortoiliac revascularization using machine learning	86
Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy	86
Using digital technologies to diagnose in the home: recommendations from a Delphi panel	85
High-dimensional item response theory analysis of patient-reported outcomes in total knee arthroplasty	85
Publisher Correction: Development and assessment of a machine learning tool for predicting emergency admission in Scotland	85
The relation between passively collected data and PTSD: a systematic review and meta-analysis	85
A Novel method for quantifying fluctuations in wearable derived daily cardiovascular parameters across the menstrual cycle	84
Demographic bias in public remote photoplethysmography datasets	83
A multimodal uncertainty-aware AI system optimizes ovarian cancer risk assessment workflow	80
Joint AI-driven event prediction and longitudinal modeling in newly diagnosed and relapsed multiple myeloma	79
Variational Bayes machine learning for risk adjustment of general outcome indicators with examples in urology	79
A Bayesian-driven approach to identify racial inequities in longitudinal care delivery	79
Matters arising: Utilizing foundation models for developing clinical tools	79
Circadian rhythm biomarker from wearable device data is related to concurrent antidepressant treatment response	79
AI-driven smartphone screening for acute COPD exacerbations: enhancing health equity in developing regions	77

Fibricheck detection capabilities for atrial fibrillation (FDA–AF): a multicenter validation study	77
Non-invasive chronic kidney disease risk stratification tool derived from retina-based deep learning and clinical factors	77
Intelligent quality control for first trimester ultrasound scans in Liaoning Province of China	76
Implementation report on pioneering federated data access for the German National Emergency Department Data Registry	76
Exploring the potential of digital biomarkers as a measure of brain health ‘capital’	75
A typology of physician input approaches to using AI chatbots for clinical decision-making	75
Anatomically-guided Masked Autoencoder with Domain-Adaptive Prompting (AMAP) for multimodal cerebral aneurysm detection and segmentation	75
Skin Tone Analysis for Representation in Educational Materials (STAR-ED) using machine learning	75
PAM: a propagation-based model for segmenting any 3D objects across multi-modal medical images	74
A Global meta-analysis of digital divide in psychiatric population from 2004 to 2023	74
Transdiagnostic-focused apps for depression and anxiety: a meta-analysis	74
AI in Histopathology Explorer for comprehensive analysis of the evolving AI landscape in histopathology	73
Large language model agents can use tools to perform clinical calculations	73
Exploiting large language models for diagnosing autism associated language disorders and identifying distinct features	73
The impact of expanded telehealth availability on primary care utilization	72
The performance of a deep learning system in assisting junior ophthalmologists in diagnosing 13 major fundus diseases: a prospective multi-center clinical trial	71
Improving medical machine learning models with generative balancing for equity and excellence	71
Disparities in cannabis use and documentation in electronic health records among children and young adults	71
When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior	70
Telehealth virtual reality intervention reduces chronic pain in a randomized crossover study	70
Do engagement and behavioural mechanisms underpin the effectiveness of the Drink Less app?	70
Physics-informed neural networks for modeling physiological time series for cuffless blood pressure estimation	69
In-ear infrasonic hemodynography with a digital health device for cardiovascular monitoring using the human audiome	69
An active inference strategy for prompting reliable responses from large language models in medical practice	68
Meta-analysis of randomized controlled trials of electronic health interventions to reduce medication errors	68
Real world evidence for altered communication patterns in individuals with autism spectrum disorder	68
ScarElastic: continuous elasticity field modeling for myocardial scar delineation in LGE-CMR	67
Integrating personalized shape prediction, biomechanical modeling, and wearables for bone stress prediction in runners	67
Artificial intelligence-based personalized treatment strategies for unresectable hepatocellular carcinoma: integrating HSP90α for prognosis and survival prediction	67
Applying machine learning to consumer wearable data for the early detection of complications after pediatric appendectomy	66
Association of accelerometer-derived circadian abnormalities and genetic risk with incidence of atrial fibrillation	66
Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer’s disease with real-world clinical validation	65
Integrating digital gait data with metabolomics and clinical data to predict outcomes in Parkinson’s disease	65
Effectiveness of telehealth versus in-person care during the COVID-19 pandemic: a systematic review	65
Crossing the chasm from model performance to clinical impact: the need to improve implementation and evaluation of AI	64
A scoping review of ethical aspects of public-private partnerships in digital health	63
From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling	63
Combined telemonitoring and telecoaching for heart failure improves outcome	63
Making machine learning matter to clinicians: model actionability in medical decision-making	62
Author Correction: Enhancing attention in children using an integrated cognitive-physical videogame: A pilot study	61
Predicting appropriateness of antibiotic treatment among ICU patients with hospital-acquired infection	61
Multimodal machine learning for risk-stratified bundled payments in spinal surgery	61
Classification of intracranial pressure epochs using a novel machine learning framework	61
Real-time near infrared artificial intelligence using scalable non-expert crowdsourcing in colorectal surgery	60
Feasibility of anomaly score detected with deep learning in irradiated breast cancer patients with reconstruction	60
A mobile health application that supports a patient centered approach to cardiovascular risk management	60
Benchmarking large language models for personalized, biomarker-based health intervention recommendations	60
Diagnosing pathologic myopia by identifying morphologic patterns using ultra widefield images with deep learning	59
Artificial intelligence tools in supporting healthcare professionals for tailored patient care	59
Deep learning-based mobile application for efficient eyelid tumor recognition in clinical images	59
Closing the gap: addressing telehealth disparities across specialties in the sustained pandemic era	59
Predicting recovery after stressors using step count data derived from activity monitors	59
Blood glucose variance measured by continuous glucose monitors across the menstrual cycle	59
Self-supervised identification and elimination of harmful datasets in distributed machine learning for medical image analysis	59
Systematic review and meta-analysis of artificial intelligence in classifying HER2 status in breast cancer immunohistochemistry	58
Optical coherence tomography choroidal enhancement using generative deep learning	58
Dynamic associations between glucose and ecological momentary cognition in Type 1 Diabetes	57
Economic evaluation for medical artificial intelligence: accuracy vs. cost-effectiveness in a diabetic retinopathy screening case	57
Examining human-AI interaction in real-world healthcare beyond the laboratory	57
Peer perceptions of clinicians using generative AI in medical decision-making	57
AI technology to support adaptive functioning in neurodevelopmental conditions in everyday environments: a systematic review	56
Prospective clinical evaluation of deep learning for ultrasonographic screening of abdominal aortic aneurysms	56
Artificial intelligence-derived retinal age gap as a marker for reproductive aging in women	56
SpeechCARE: dynamic multimodal modeling for cognitive screening in diverse linguistic and speech task contexts	55
Deep learning-enabled multiphoton microscopy predicts colorectal cancer recurrence from routine FFPE specimens	55
A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer	55
Development and validation of an interpretable risk prediction model for the early classification of thalassemia	54
Diagnostic accuracy of telemedicine for detection of surgical site infection: a systematic review and meta-analysis	54
Inter-individual variation in objective measure of reactogenicity following COVID-19 vaccination via smartwatches and fitness bands	54
Improving prognostic accuracy in lung transplantation using unique features of isolated human lung radiographs	53
The three-year evolution of Germany’s Digital Therapeutics reimbursement program and its path forward	53
Responsible development of clinical speech AI: Bridging the gap between clinical research and technology	53
Evaluating commercial multimodal AI for diabetic eye screening and implications for an alternative regulatory pathway	52
Engaging a national-scale cohort of smart thermometer users in participatory surveillance	52
Health data justice: building new norms for health data governance	52
Implementing quality management systems to close the AI translation gap and facilitate safe, ethical, and effective health AI solutions	52
The hospital at home in the USA: current status and future prospects	51
Interpretable multimodal transformer for prediction of molecular subtypes and grades in adult-type diffuse gliomas	51
Machine learning for technical skill assessment in surgery: a systematic review	51
The case for inclusive co-creation in digital health innovation	51

Shortcut learning in medical AI hinders generalization: method for estimating AI model generalization without external data	51
African digital health strategic plans analysis: key weaknesses in contextualization, intervention focus, and technological foresight	50
A framework for digital health equity	50
Comparative analysis of natural language processing methodologies for classifying computed tomography enterography reports in Crohn’s disease patients	50
Accuracy of dental implant placement using different dynamic navigation and robotic systems: an in vitro study	50
A simulation based digital twin approach to assessing the organization of response to emergency calls	50
Reimbursement in the age of generalist radiology artificial intelligence	49
Knockoff-ML: a knockoff machine learning framework for controlled variable selection and risk stratification in electronic health record data	49
Machine learning based CAGIB score predicts in-hospital mortality of cirrhotic patients with acute gastrointestinal bleeding	48
Digital twin models for predicting venetoclax and azacitidine-induced neutropenia in patients with acute myeloid leukemia	47
Pandemic-proof recruitment and engagement in a fully decentralized trial in atrial fibrillation patients (DeTAP)	47
Streamlined machine learning model for early sepsis risk prediction in burn patients	47
Leveraging large language models to extract smoking history from clinical notes for lung cancer surveillance	47
Virtual fitness buddy ecosystem: a mixed reality precision health physical activity intervention for children	47
Expanding care coordination in an integrated health system through causal machine learning	47
Therapeutic outcomes of different treatment approaches for T1a-M3/T1b esophageal cancer and development of a prognostic prediction model	47
Cross sectional pilot study on clinical review generation using large language models	47
Could transparent model cards with layered accessible information drive trust and safety in health AI?	46
Continuous and componentized facial palsy measurement alignment and clinical interpretable model	46
Generative artificial intelligence: the ‘more knowledgeable other’ in a social constructivist framework of medical education	46
Federated target trial emulation using distributed observational data for treatment effect estimation	46
Shedding light on the dynamic interplay of positive and negative symptoms of psychosis with Behavioral Tractography	46
The industry impact of the American Medical Association’s Digital Medicine Payment Advisory Group (DMPAG)	45
Digital twins for the era of personalized surgery	45
Prostate cancer therapy personalization via multi-modal deep learning on randomized phase III clinical trials	45
Predicting non-muscle invasive bladder cancer outcomes using artificial intelligence: a systematic review using APPRAISE-AI	45
Artificial intelligence for surgical scene understanding: a systematic review and reporting quality meta-analysis	45
Estimation of minimal data sets sizes for machine learning predictions in digital mental health interventions	44
Guidance for unbiased predictive information for healthcare decision-making and equity (GUIDE): considerations when race may be a prognostic factor	44
Rating analysis and BERTopic modeling of consumer versus regulated mHealth app reviews in Germany	44
A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis	44
Towards precision medicine based on a continuous deep learning optimization and ensemble approach	44
Explainable medical imaging AI needs human-centered design: guidelines and evidence from a systematic review	43
Multimodal deep learning for cancer prognosis prediction with clinical information prompts integration	43
Machine learning-enabled spatial multi-omics uncovers lactate-driven targets and tumor microenvironmental reprogramming in cancer	43
Medical foundation large language models for comprehensive text analysis and beyond	43
Regular snoring is associated with uncontrolled hypertension	43
Systematic review and meta-analysis of performance of wearable artificial intelligence in detecting and predicting depression	43
Digital biomarkers for non-motor symptoms in Parkinson’s disease: the state of the art	43
Assessing and alleviating state anxiety in large language models	42
Explainable artificial intelligence for mental health through transparency and interpretability for understandability	42
Digital health application integrating wearable data and behavioral patterns improves metabolic health	42
A strategy for cost-effective large language model use at health system-scale	42
Prediction of atrial fibrillation from at-home single-lead ECG signals without arrhythmias	42
Digital humanistic program to manage premature frailty in young breast cancer survivors with gender perspective	42
A critical assessment of using ChatGPT for extracting structured data from clinical notes	42
How predictive medicine leads to solidarity gaps in health	42
Capturing relationships between suturing sub-skills to improve automatic suturing assessment	41
Has increased telehealth access during COVID-19 led to over-utilization of primary care?	41
Mobile application leads to psychological improvement and correlated neuroimmune function change in subjective cognitive decline	41
Interpretable machine learning model for digital lung cancer prescreening in Chinese populations with missing data	41
From ageing clocks to human digital twins in personalising healthcare through biological age analysis	40
Natural language processing in mixed-methods evaluation of a digital sleep-alcohol intervention for young adults	40
Economic analysis of an AI-enabled ECG alert system: impact on mortality outcomes from a pragmatic randomized trial	39
High-resolution lifestyle profiling and metabolic subphenotypes of type 2 diabetes	39
Machine learning-based quantitative prediction of drug exposure in drug-drug interactions using drug label information	39
Assessment of priorities, quality, and inclusivity of digital therapeutics trials in China	39
AI-driven preclinical disease risk assessment using imaging in UK biobank	39
A systematic review of digital and face-to-face cognitive behavioral therapy for depression	39
A systems approach towards remote health-monitoring in older adults: Introducing a zero-interaction digital exhaust	38
Culture-free detection of bacteria from blood for rapid sepsis diagnosis	38
Legal implications of AI standard of care integration on patients’ informed consent: lessons from surgery	38
Preventing mental illness in children that experienced maltreatment the efficacy of REThink online therapeutic game	38
Multimodal AI for risk stratification in autism spectrum disorder: integrating voice and screening tools	37
Implementation of cloud computing in the German healthcare system	37
Smartphone keyboard dynamics predict affect in suicidal ideation	37
Whole-heart electromechanical simulations using Latent Neural Ordinary Differential Equations	37
Accurately predicting mood episodes in mood disorder patients using wearable sleep and circadian rhythm features	37
Towards trustworthy seizure onset detection using workflow notes	37
Clinical entity augmented retrieval for clinical information extraction	36
Establishing the longitudinal hemodynamic mapping framework for wearable-driven coronary digital twins	36
Predicting radiocephalic arteriovenous fistula success with machine learning	36
Unsupervised machine learning to investigate trajectory patterns of COVID-19 symptoms and physical activity measured via the MyHeart Counts App and smart devices	36
Indigenous data governance approaches applied in research using routinely collected health data: a scoping review	36
Predictive modeling of hemodynamics during viscerosensory neurostimulation via neural computation mechanism in the brainstem	36
The clinician-AI interface: intended use and explainability in FDA-cleared AI devices for medical image interpretation	36
Considerations for addressing bias in artificial intelligence for health equity	35
Collection of the digital data from the neurological examination	35
A framework for human evaluation of large language models in healthcare derived from literature review	35
Identifying major impact factors affecting the continuance intention of mHealth: a systematic review and multi-subgroup meta-analysis	35
Computer vision in surgery: from potential to clinical value	35
Author Correction: Developing a Canadian artificial intelligence medical curriculum using a Delphi study	34
Author Correction: Small language models learn enhanced reasoning skills from medical textbooks	34
Author Correction: A computational framework for discovering digital biomarkers of glycemic control	34
Deep learning to quantify care manipulation activities in neonatal intensive care units	34
Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer	34
Identifying vulnerable populations in the electronic Framingham Heart Study to improve digital device adherence	34
Overcoming biases of individual level shopping history data in health research	33
Considerations for integrating wearables into the everyday healthcare practice	33
Interpretable arrhythmia detection in ECG scans using deep learning ensembles: a genetic programming approach	33
Survey, taxonomy, and emerging paradigms of societal digital twins for public health preparedness	33
Probing the limits and capabilities of diffusion models for the anatomic editing of digital twins	33
Computational drug repurposing in the age of COVID-19: mixing antiviral cocktails in silico	33
Medical domain knowledge in domain-agnostic generative AI	33
Clinical trials informed framework for real world clinical implementation and deployment of artificial intelligence applications	32