npj Digital Medicine

Article	Citations
Modelling the impact of environmental and social determinants on mental health using generative agents	492
Transforming diagnosis through artificial intelligence	465
Challenges and recommendations for enhancing digital data protection in Indian Medical Research and Healthcare Sector	435
Association between exposure to particulate matter and heart rate variability in vulnerable and susceptible individuals	404
A systematic review of consumers’ and healthcare professionals’ trust in digital healthcare	340
A new metric to understand the association between heart rate variability and menstrual regularity	318
Machine learning on interictal intracranial EEG predicts surgical outcome in drug resistant epilepsy	272
Red teaming ChatGPT in medicine to yield real-world insights on model behavior	245
Evaluating base and retrieval augmented LLMs with document or online support for evidence based neurology	206
Digital twins in dermatology, current status, and the road ahead	204
Silhouette images enable estimation of body fat distribution and associated cardiometabolic risk	198
Whole slide image based deep learning refines prognosis and therapeutic response evaluation in lung adenocarcinoma	194
3D convolutional deep learning for nonlinear estimation of body composition from whole body morphology	187
Application of multimodal large language models for safety indicator calculation and contraindication prediction in laser vision correction	181
Real world data on digital remote refraction in a healthy population of 14,680 eyes	170
Why we should not mistake accuracy of medical AI for efficiency	151
The evolution of digital health technologies in cardiovascular disease research	150
Predicting deterioration in dengue using a low cost wearable for continuous clinical monitoring	149
Learning from Online Video Education (LOVE) improves confidence in fertility treatments: a randomized controlled trial	148
Learnings from the first AI-enabled skin cancer device for primary care authorized by FDA	140
The triple integration of data, users and policies required for successful climate health solutions	138
Predicting clinical pathways of traumatic brain injuries (TBIs) through process mining	137
Comparing self reported and physiological sleep quality from consumer devices to depression and neurocognitive performance	137
Clinically meaningful interpretability of an AI model for ECG classification	136
Digital twin brain simulator for real-time consciousness monitoring and virtual intervention using primate electrocorticogram data	134

Author Correction: Towards the automatic detection of social biomarkers in autism spectrum disorder: introducing the simulated interaction task (SIT)	127
Defining digital surgery for the future	122
Developing a shared sepsis data infrastructure: a systematic review and concept map to FHIR	122
Addressing racial disparities in surgical care with machine learning	121
Identification of robust deep neural network models of longitudinal clinical measurements	117
Covid-19 vaccination and menstrual cycle length in the Apple Women’s Health Study	116
Short- and long-term effects of an electronic medication management system on paediatric prescribing errors	115
Predictive models in emergency medicine and their missing data strategies: a systematic review	112
A standardized framework for risk-based assessment of treatment effect heterogeneity in observational healthcare databases	110
The Apple Watch spO2 sensor and outliers in healthy users	108
A systematic review of healthcare provider-targeted mobile applications for non-communicable diseases in low- and middle-income countries	102
Author Correction: Prostate cancer therapy personalization via multi-modal deep learning on randomized phase III clinical trials	101
Author Correction: Development and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection	100
Understanding the scalability of personalised monitoring within indoor spaces	100
The IMPACT framework and implementation for accessible in silico clinical phenotyping in the digital era	99
Early-stage COVID-19 pandemic observations on pulmonary embolism using nationwide multi-institutional data harvesting	99
Effectiveness of automated alerting system compared to usual care for the management of sepsis	97
An example of governance for AI in health services from Aotearoa New Zealand	95
Higher sensitivity monitoring of reactions to COVID-19 vaccination using smartwatches	94
A multicenter study on two-stage transfer learning model for duct-dependent CHDs screening in fetal echocardiography	91
Matters Arising: Immortal time bias in the analysis of drug prescription trajectories	90
Associations between adoption of eHealth management module and optimal control of HbA1c in diabetes patients	89
An optimization framework to guide the choice of thresholds for risk-based cancer screening	87
Author Correction: Virtual exam for Parkinson’s disease enables frequent and reliable remote measurements of motor function	86
Examining technology-assisted rehabilitation for older adults’ functional mobility: a network meta-analysis on efficacy and acceptability	85
Mapping digital health ecosystems in Africa in the context of endemic infectious and non-communicable diseases	85
Evaluating reliability in wearable devices for sleep staging	83
The Iterative Mindset Method: a neuroscientific theoretical approach for sustainable behavior change and weight-loss in digital medicine	83
Predictive analytics for cardio-thoracic surgery duration as a stepstone towards data-driven capacity management	82
Unraveling cradle-to-grave disease trajectories from multilayer comorbidity networks	81
Prevalence and course of pregnancy symptoms using self-reported pregnancy app symptom tracker data	81
Digital lifestyle treatment improves long-term metabolic control in type 2 diabetes with different effects in pathophysiological and genetic subgroups	79
Constructing personalized characterizations of structural brain aberrations in patients with dementia using explainable artificial intelligence	79
Development of an effective predictive screening tool for prostate cancer using the ClarityDX machine learning platform	77
Generalized sleep decoding with basal ganglia signals in multiple movement disorders	76
Predicting recurrent chat contact in a psychological intervention for the youth using natural language processing	76
A multi-center study on the adaptability of a shared foundation model for electronic health records	74
Can artificial intelligence improve medicine’s uncomfortable relationship with Maths?	74
Validation and application of computer vision algorithms for video-based tremor analysis	74
Dose–response relationship between computerized cognitive training and cognitive improvement	72
Derivation, external and clinical validation of a deep learning approach for detecting intracranial hypertension	72
Deep learning-based prediction of Clostridioides difficile infection caused by antibiotics using longitudinal electronic health records	72
Author Correction: Self-supervised learning of accelerometer data provides new insights for sleep and its association with mortality	72
Evidence-based health messages increase intention to cope with loneliness in Germany: a randomized controlled online trial	71
How can regulation and reimbursement better accommodate flexible suites of digital health technologies?	67
AI-based analysis of CT images for rapid triage of COVID-19 patients	66
Early adverse physiological event detection using commercial wearables: challenges and opportunities	66
Biometrics of complete human pregnancy recorded by wearable devices	64
Characterization of activity behavior using a digital medicine system and comparison to medication ingestion in patients with serious mental illness	64
Artificial intelligence estimated electrocardiographic age as a recurrence predictor after atrial fibrillation catheter ablation	62

India’s evolving digital health strategy	60
Effect of clinical decision support for severe hypercholesterolemia on low-density lipoprotein cholesterol levels	59
MyThisYourThat for interpretable identification of systematic bias in federated learning for biomedical images	59
Physical activity and sleep changes among children during the COVID-19 pandemic	58
Clinical usefulness of digital twin guided virtual amiodarone test in patients with atrial fibrillation ablation	57
Medical records-based chronic kidney disease phenotype for clinical care and “big data” observational and genetic studies	57
Systematic review to understand users perspectives on AI-enabled decision aids to inform shared decision making	57
Exergaming and cognitive functions in people with mild cognitive impairment and dementia: a meta-analysis	56
Human AI collaboration for unsupervised categorization of live surgical feedback	55
Mobile Health: making the leap to research and clinics	55
Fast and accurate prediction of drug induced proarrhythmic risk with sex specific cardiac emulators	54
Using a Digital Neuro Signature to measure longitudinal individual-level change in Alzheimer’s disease: the Altoida large cohort study	54
Smartphone application improves fertility treatment-related literacy in a large-scale virtual randomized controlled trial in Japan	54
Predicting critical state after COVID-19 diagnosis: model development using a large US electronic health record dataset	54
AI-enhanced reconstruction of the 12-lead electrocardiogram via 3-leads with accurate clinical assessment	53
Predictive structured–unstructured interactions in EHR models: A case study of suicide prediction	52
Empowering clinical research in a decentralized world	51
Author Correction: Games Wide Open to athlete partnership in building artificial intelligence systems	49
Robust automated calcification meshing for personalized cardiovascular biomechanics	49
Author Correction: Reopening businesses and risk of COVID-19 transmission	49
Regulatory considerations for developing remote measurement technologies for Alzheimer’s disease research	49
A prospective comparison of two computer aided detection systems with different false positive rates in colonoscopy	48
Predicting control of cardiovascular disease risk factors in South Asia using machine learning	48
An automated COVID-19 triage pipeline using artificial intelligence based on chest radiographs and clinical data	48
Public evidence on AI products for digital pathology	48
Efficient cellular annotation of histopathology slides with real-time AI augmentation	47
Foundations of a knee joint digital twin from qMRI biomarkers for osteoarthritis and knee replacement	47
Computer-aided interpretation of chest radiography reveals the spectrum of tuberculosis in rural South Africa	47
A novel AI device for real-time optical characterization of colorectal polyps	47
Effectiveness of DialBetesPlus, a self-management support system for diabetic kidney disease: Randomized controlled trial	47
The principles of whole-hospital predictive analytics monitoring for clinical medicine originated in the neonatal ICU	46
Video-based physiologic monitoring: promising applications for the ICU and beyond	45
Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis	45
Watching Parkinson’s disease with wrist-based sensors	44
Better Understanding of the Metamorphosis of Pregnancy (BUMP): protocol for a digital feasibility study in women from preconception to postpartum	44
AI-based skin cancer detection: the balance between access and overutilization	43
Continuous monitoring of surgical bimanual expertise using deep neural networks in virtual reality simulation	43
Algorithmic fairness in pandemic forecasting: lessons from COVID-19	43
Simulated trials: in silico approach adds depth and nuance to the RCT gold-standard	42
Bias recognition and mitigation strategies in artificial intelligence healthcare applications	42
Enhancing diagnostic capability with multi-agents conversational large language models	42
Continuous time and dynamic suicide attempt risk prediction with neural ordinary differential equations	42
A caution against customized AI in healthcare	41
The utility of personal wearable data in long COVID and personalized patient care	41
Emerging sensing and modeling technologies for wearable and cuffless blood pressure monitoring	40
A randomized trial of a mobile health intervention to augment cardiac rehabilitation	40
Time and event-specific deep learning for personalized risk assessment after cardiac perfusion imaging	40
Diagnostic performance of artificial intelligence-assisted PET imaging for Parkinson’s disease: a systematic review and meta-analysis	40
A hybrid machine learning approach for the personalized prognostication of aggressive skin cancers	40
Deep representation learning identifies associations between physical activity and sleep patterns during pregnancy and prematurity	40
DRG-LLaMA : tuning LLaMA model to predict diagnosis-related group for hospitalized patients	40
Digital twin assisted surgery, concept, opportunities, and challenges	40
A unifying force for the realization of medical AI	39
Closing the gap between open source and commercial large language models for medical evidence summarization	39
Promoting racial equity in digital health: applying a cross-disciplinary equity framework	39
Can Apple and Google continue as health app gatekeepers as well as distributors and developers?	39
Integrating Internet multisource big data to predict the occurrence and development of COVID-19 cryptic transmission	39
Computational drug repurposing based on electronic health records: a scoping review	38
The impact of inconsistent human annotations on AI driven clinical decision making	38
Co-evolution of machine learning and digital technologies to improve monitoring of Parkinson’s disease motor symptoms	38
Solving the explainable AI conundrum by bridging clinicians’ needs and developers’ goals	38
International electronic health record-derived post-acute sequelae profiles of COVID-19 patients	38
Health digital twins as tools for precision medicine: Considerations for computation, implementation, and regulation	38
The path forward for large language models in medicine is open	37
Automated video-based assessment of facial bradykinesia in de-novo Parkinson’s disease	37
Recommendations for the use of pediatric data in artificial intelligence and machine learning ACCEPT-AI	37
A systematic umbrella review and meta-meta-analysis of eHealth and mHealth interventions for improving lifestyle behaviours	37
Modeling personalized heart rate response to exercise and environmental factors with wearables data	36
Evaluation of remote digital postoperative wound monitoring in routine surgical practice	36
Machine learning for accurate estimation of fetal gestational age based on ultrasound images	36
Internet- and mobile-based psychological interventions for post-traumatic stress symptoms in youth: a systematic review and meta-analysis	36
Validation of Amazon Halo Movement: a smartphone camera-based assessment of movement health	36
Mining the contribution of intensive care clinical course to outcome after traumatic brain injury	35
A high-generalizability machine learning framework for predicting the progression of Alzheimer’s disease using limited data	35
Digital therapeutics from bench to bedside	35
Mapping each pre-existing condition’s association to short-term and long-term COVID-19 complications	35
40 years of actigraphy in sleep medicine and current state of the art algorithms	34
An artificial intelligence system for predicting the deterioration of COVID-19 patients in the emergency department	34
A randomized controlled trial investigating experiential virtual reality communication on prudent antibiotic use	34
Deep learning based highly accurate transplanted bioengineered corneal equivalent thickness measurement using optical coherence tomography	34

Clinical knowledge extraction via sparse embedding regression (KESER) with multi-center large scale electronic health record data	34
Privacy preserving strategies for electronic health records in the era of large language models	33
An artificial intelligence based app for skin cancer detection evaluated in a population based setting	33
Evidence from ClinicalTrials.gov on the growth of Digital Health Technologies in neurology trials	33
Artificial intelligence to detect malignant eyelid tumors from photographic images	33
Internet- and mobile-based psychological interventions for sexual dysfunctions: a systematic review and meta-analysis	33
Use of automated conversational agents in improving young population mental health: a scoping review	33
Semi automatic quantification of REM sleep without atonia in natural sleep environment	33
U-Sleep’s resilience to AASM guidelines	33
The ethics of ChatGPT in medicine and healthcare: a systematic review on Large Language Models (LLMs)	32
Automated clinical coding: what, why, and where we are?	32
The diagnostic and triage accuracy of digital and online symptom checker tools: a systematic review	32
Digital health for environmentally sustainable cancer screening	32
Comparing scientific abstracts generated by ChatGPT to real abstracts with detectors and blinded human reviewers	32
Prediction across healthcare settings: a case study in predicting emergency department disposition	32
A medical multimodal large language model for future pandemics	31
Internet-based and mobile-based cognitive behavioral therapy for chronic diseases: a systematic review and meta-analysis	31
Yet Another Automated Gleason Grading System (YAAGGS) by weakly supervised deep learning	31
Technology-supported behavior change interventions for reducing sodium intake in adults: a systematic review and meta-analysis	31
Deploying digital health tools within large, complex health systems: key considerations for adoption and implementation	31
An adversarial training framework for mitigating algorithmic biases in clinical machine learning	30
An intriguing vision for transatlantic collaborative health data use and artificial intelligence development	30
Effectiveness of gamified team competition as mHealth intervention for medical interns: a cluster micro-randomized trial	30
Multimodal deep learning of fundus abnormalities and traditional risk factors for cardiovascular risk prediction	29
Digital medicine and the curse of dimensionality	29
Broadening the reach of the FDA Sentinel system: A roadmap for integrating electronic health record data in a causal analysis framework	29
Clinical artificial intelligence quality improvement: towards continual monitoring and updating of AI algorithms in healthcare	29
Privacy-preserving large language models for structured medical information retrieval	28
A large language model for electronic health records	28
A deep learning-based electrocardiogram risk score for long term cardiovascular death and disease	28
AI-assisted prediction of differential response to antidepressant classes using electronic health records	28
Evaluating multimodal AI in medical diagnostics	28
The health digital twin to tackle cardiovascular disease—a review of an emerging interdisciplinary field	28
Zero shot health trajectory prediction using transformer	28
Informing immunotherapy with multi-omics driven machine learning	28
Health app policy: international comparison of nine countries’ approaches	28
Natural language processing system for rapid detection and intervention of mental health crisis chat messages	28
A deep learning system for myopia onset prediction and intervention effectiveness evaluation in children	28
A scoping review of reporting gaps in FDA-approved AI medical devices	27
Predicting patient decompensation from continuous physiologic monitoring in the emergency department	27
Implementing large language models in healthcare while balancing control, collaboration, costs and security	27
Foundation metrics for evaluating effectiveness of healthcare conversations powered by generative AI	27
Identifying and forecasting importation and asymptomatic spreaders of multi-drug resistant organisms in hospital settings	27
AI in Histopathology Explorer for comprehensive analysis of the evolving AI landscape in histopathology	27
Large language model agents can use tools to perform clinical calculations	27
Regulatory considerations for successful implementation of digital endpoints in clinical trials for drug development	27
Unregulated large language models produce medical device-like output	27
Real world evidence for altered communication patterns in individuals with autism spectrum disorder	26
Development and external validation of a pretrained deep learning model for the prediction of non-accidental trauma	26
Games Wide Open to athlete partnership in building artificial intelligence systems	26
Privacy enhancing and generalizable deep learning with synthetic data for mediastinal neoplasm diagnosis	26
The effects of a digital health intervention on patient activation in chronic kidney disease	26
Identification of Parkinson’s disease PACE subtypes and repurposing treatments through integrative analyses of multimodal data	26
Variational Bayes machine learning for risk adjustment of general outcome indicators with examples in urology	26
Results and implications for generative AI in a large introductory biomedical and health informatics course	26
Holistic AI analysis of hybrid cardiac perfusion images for mortality prediction	26
The long but necessary road to responsible use of large language models in healthcare research	26
Development and assessment of a machine learning tool for predicting emergency admission in Scotland	26
Phenotype driven molecular genetic test recommendation for diagnosing pediatric rare disorders	26
Harnessing the power of longitudinal medical imaging for eye disease prognosis using Transformer-based sequence modeling	26
Development features and study characteristics of mobile health apps in the management of chronic conditions: a systematic review of randomised trials	25
Clinical impact and quality of randomized controlled trials involving interventions evaluating artificial intelligence prediction tools: a systematic review	25
Publisher Correction: Development and assessment of a machine learning tool for predicting emergency admission in Scotland	25
A randomized trial testing digital medicine support models for mild-to-moderate alcohol use disorder	25
Artificial intelligence related safety issues associated with FDA medical device reports	25
Author Correction: Low-count whole-body PET with deep learning in a multicenter and externally validated study	25
Wearables as a tool for measuring therapeutic adherence in behavioral health	25
A randomized controlled trial enhancing viral hepatitis testing in primary care via digital crowdsourced intervention	24
Simulating A/B testing versus SMART designs for LLM-driven patient engagement to close preventive care gaps	24
A Novel method for quantifying fluctuations in wearable derived daily cardiovascular parameters across the menstrual cycle	24
Author Correction: Feasibility of anomaly score detected with deep learning in irradiated breast cancer patients with reconstruction	24
An integrated framework for identifying clinical-laboratory indicators for novel pandemics: COVID-19 and MIS-C	24
Economic evaluation and analyses of hospital-based electronic medical records (EMRs): a scoping review of international literature	24
A machine learning framework supporting prospective clinical decisions applied to risk prediction in oncology	24
Enhancing serious illness communication using artificial intelligence	24
A systematic review of engagement reporting in remote measurement studies for health symptom tracking	24
Digital health tools to support parents with parent-infant sleep and mental well-being	23
Preferences and willingness-to-pay for a blood pressure telemonitoring program using a discrete choice experiment	23
Assessment of ownership of smart devices and the acceptability of digital health data sharing	23
The impact of expanded telehealth availability on primary care utilization	23
Digital mental health for postpartum women: perils, pitfalls, and promise	23
Association of accelerometer-derived circadian abnormalities and genetic risk with incidence of atrial fibrillation	23
Robust language-based mental health assessments in time and space through social media	23
How AI can learn from the law: putting humans in the loop only on appeal	23
In-ear infrasonic hemodynography with a digital health device for cardiovascular monitoring using the human audiome	23
Using digital technologies to diagnose in the home: recommendations from a Delphi panel	23
A scoping review of portable sensing for out-of-lab anterior cruciate ligament injury prevention and rehabilitation	23
Do engagement and behavioural mechanisms underpin the effectiveness of the Drink Less app?	22
Regulatory responses and approval status of artificial intelligence medical devices with a focus on China	22
Artificial intelligence-enhanced electrocardiography derived body mass index as a predictor of future cardiometabolic disease	22
The performance of a deep learning system in assisting junior ophthalmologists in diagnosing 13 major fundus diseases: a prospective multi-center clinical trial	22
Blending space and time to talk about cancer in extended reality	22
Wireless facial biosensing system for monitoring facial palsy with flexible microneedle electrode arrays	22
An aligned framework of actively collected and passively monitored clinical outcome assessments (COAs) for measure selection	22
Joint AI-driven event prediction and longitudinal modeling in newly diagnosed and relapsed multiple myeloma	22