OOIR: Observatory of International Research

Papers

(The TQCC of Human Reproduction Open is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Follicle-stimulating hormone stimulates free radical generation without inducing substantial oxidative stress in human granulosa cells	724
Paternal age and neonatal outcomes: a population-based cohort study	159
Birth defects reporting and the use of dydrogesterone: a disproportionality analysis from the World Health Organization pharmacovigilance database (VigiBase)	119
Unmasking the risk: clinical trials versus real-world evidence on dydrogesterone and birth defects	104
Association between maternal MTHFR C677T/A1298C combination polymorphisms and IVF/ICSI outcomes: a retrospective cohort study	99
Finding truth in an ocean of evidence	87
ESHRE guideline: medically assisted reproduction in patients with a viral infection/disease	74
The prevalence of SARS-CoV-2 antibodies in triage-negative patients and staff of a fertility setting from lockdown release throughout 2020	64
A systematic review of outcome reporting and outcome measures in studies investigating uterine-sparing treatment for adenomyosis	61
Outcome reporting across randomized controlled trials evaluating potential treatments for male infertility: a systematic review	53
Conventional outcome reporting per IVF cycle/embryo transfer may systematically underestimate chances of success for women undergoing ART: relevant biases in registries, epidemiological studies, and g	45
Reproductive outcomes following recurrent first-trimester miscarriage: a retrospective cohort study	42
A concise infertility work-up results in fewer pregnancies	39
Pretreatment with oral contraceptive pills in women with PCOS scheduled for IVF: a randomized clinical trial	35
Risk factors associated with monozygotic twinning in offspring conceived by assisted reproductive technology	34
COVID-19 pandemic and the consequential effect on patients with endometriosis	34
Uterine fluid cytokine/chemokine levels of women undergoing ART with and without oral Vitamin D supplementation	33
Endometriosis classification systems: an international survey to map current knowledge and uptake	33
Lab-based semen parameters as predictors of long-term health in men—a systematic review	33
Gamete donation: anti-anonymity does not equate to anti-donation	33
Women’s preferences concerning IVF treatment: a discrete choice experiment with particular focus on embryo transfer policy	33
Infertility and pregnancy outcomes among adults with primary ciliary dyskinesia	33
Predicting serum hormone concentration by estimation of urinary hormones through a home-use device	30
HROpen—open, accessible and now with an impact factor!	20
The lack of evidence behind over-the-counter antioxidant supplements for male fertility patients: a scoping review	19

Reply to: ‘Hiding in plain sight’ and ‘Caution is needed when communicating analyses based on an apple to orange comparison’	18
Extracellular vesicles secreted by human aneuploid embryos present a distinct transcriptomic profile and upregulate MUC1 transcription in decidualised endometrial stromal cells	17
Speaking up for the safety of the children following frozen embryo transfer	17
Reply: Emerging evidence of endometrial compaction in predicting ART outcomes	16
Is retrograde menstruation a universal, recurrent, physiological phenomenon? A systematic review of the evidence in humans and non-human primates	15
Women’s reproductive span: a systematic scoping review	15
Preconception depression reduces fertility: a couple-based prospective preconception cohort	15
Anxiety in couples undergoing IVF: evidence from E-Freeze randomised controlled trial	15
Will a government subsidy increase couples’ further fertility intentions? A real-world study from a large-scale online survey in Eastern China	15
Associations between synthetic phenols, phthalates, and placental growth/function: a longitudinal cohort with exposure assessment in early pregnancy	14
Pronuclear transfer rescues poor embryo development of in vitro-grown secondary mouse follicles	14
Financial costs of assisted reproductive technology for patients in low- and middle-income countries: a systematic review	14
Lifestyle intervention prior to IVF does not improve embryo utilization rate and cumulative live birth rate in women with obesity: a nested cohort study	14
The microbiome in reproductive health: protocol for a systems biology approach using a prospective, observational study design	13
ESGO/ESHRE/ESGE Guidelines for the fertility-sparing treatment of patients with endometrial carcinoma,	13
Endometriosis and oocyte quality: an analysis of 13 614 donor oocyte recipient and autologous IVF cycles	13
Good practice recommendations for information provision for those involved in reproductive donation†	12
Evidence-based guideline: premature ovarian insufficiency,	12
A comparison of perinatal outcomes following fresh blastocyst or cleavage stage embryo transfer in singletons and twins and between singleton siblings	12
Visceral and subcutaneous adipose tissue in children born after assisted reproductive technology with frozen and fresh embryo transfers	11
Infertility prevalence and the methods of estimation from 1990 to 2021: a systematic review and meta-analysis	10
The forgotten group of donor-conceived persons	10
The effect of frozen embryo transfer regimen on the association between serum progesterone and live birth: a multicentre prospective cohort study (ProFET)	9
Blastocyst quality and perinatal outcomes in women undergoing single blastocyst transfer in frozen cycles	9
The needs of subfertile couples continuing to attempt natural conception: in-depth interviews	9
Adolescent attachment to parents and peers in singletons and twins born with assisted and natural conception	9
The risk of Type 1 diabetes in children born after ART: a Nordic cohort study from the CoNARTaS group	9
Situating commercialization of assisted reproduction in its socio-political context: a critical interpretive synthesis	9
Blastocyst telomere length predicts successful implantation after frozen-thawed embryo transfer	8
Birth outcomes in mothers with hypertensive disorders and polycystic ovary syndrome: a population-based cohort study	8
‘There will be blood’† A proof of concept for the role of haemorrhagic corpora lutea in the pathogenesis of endometriosis	8
Toxic elements in follicular fluid adversely influence the likelihood of pregnancy and live birth in women undergoing IVF	8
The long and winding road leading to evidence-based medicine	7
Caution is needed when communicating analyses based on an apple to orange comparison	7
Binucleated embryos at the two-cell stage show higher blastocyst formation rates and higher pregnancy and live birth rates compared to non-multinucleated embryos	7
A comprehensive study of common and rare genetic variants in spermatogenesis-related loci identifies new risk factors for idiopathic severe spermatogenic failure	7
Dysregulation of endometrial stromal serotonin homeostasis leading to abnormal phosphatidylcholine metabolism impairs decidualization in patients with recurrent implantation failure	7
No additional risk of congenital anomalies after first-trimester dydrogesterone use: a systematic review and meta-analysis	7
Characteristics of menstrual cycles with or without intercourse in women with no known subfertility	7
Endometrial compaction to predict pregnancy outcomes in patients undergoing assisted reproductive technologies: a systematic review and meta-analysis	7
The risk of asthma in singletons conceived by ART: a retrospective cohort study	7
Clinical and ethical perspectives of ovarian stimulation and oocyte cryopreservation in adolescents: 6 years experience from a tertiary centre	7
Oocyte activation deficiency and assisted oocyte activation: mechanisms, obstacles and prospects for clinical application	7
In infertile women with subclinical hypothyroidism, with or without thyroid peroxidase antibodies, serum TSH during pregnancy follows preconception values and thyroid hormones remain stable	7
Reply: Inaccurate measures of outcomes in the two-sample Mendelian randomization of vitamin D with miscarriage	7
Human Reproduction Open, a wild mustang in the prairie of science	7
The interplay between mitochondrial DNA genotypes, female infertility, ovarian response, and mutagenesis in oocytes	7