OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Chemical Biology is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Antisense-mediated senseful regulation of orchestrated metabolic response	121
New sheriff in town: Cyclic peptide inhibitors of a DUB module	116
CBLs downregulation foretells T cell ubiquitination leading to autoimmunity	87
Therapeutic potential of inhibiting the PI3Kγ complex for leukemia	80
Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1	79
A versatile residue numbering scheme for Nav and Cav channels	77
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance	76
Advances in spatial proteomics: Mapping proteome architecture from protein complexes to subcellular localizations	72
Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples	71
Heterologous characterization of mechercharmycin A biosynthesis reveals alternative insights into post-translational modifications for RiPPs	70
A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer	70
Meet the Authors: Christopher R. Mansfield and Emily R. Derbyshire	69
Voices: Challenges and opportunities in regulating the immune system	69
Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites	66
Next steps for targeted protein degradation	66
RENBP inhibition amplifies metabolic glycan labeling efficiency of antigen-presenting cells in vitro and in vivo	66
A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection	65
Acute pharmacological degradation of ERK5 does not inhibit cellular immune response or proliferation	64
2′-OH as a universal handle for studying intracellular RNAs	62
Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development	60
Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine	59
ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas	58
FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication	56
Target deconvolution with matrix-augmented pooling strategy reveals cell-specific drug-protein interactions	55
Meet the Authors: Harkamal S. Jhajj and Peter M. Tessier	54

Meet the Cell Chemical Biology author and newest advisory board member: Marcus Conrad	53
A complex puzzle: Regulation of SLFN12 RNase activity by phosphorylation	50
Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells	50
Real-time non-invasive fluorescence imaging of gut commensal bacteria to detect dynamic changes in the microbiome of live mice	49
Catalytic spike antibodies: A new paradigm in neutralization	49
Valence and avidity determine the agonistic activity of anti-TNFR2 nanobody fusion proteins	48
Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy	47
PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ	46
Mechanisms by which microbiome-derived metabolites exert their impacts on neurodegeneration	44
A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux	44
A fine-tuned azobenzene for enhanced photopharmacology in vivo	42
Beyond antibiotic resistance: The whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria	41
N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis	41
Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET	41
A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation	41
A double whammy for KEAP1	40
Pharmacological management of disease by overcoming structural adversity	40
Metabolic tug-of-war: Microbial metabolism shapes colonization resistance against enteric pathogens	40
BLOC-1 and BORC: Complex regulators of endolysosomal dynamics	40