OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Chemical Biology is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
CBLs downregulation foretells T cell ubiquitination leading to autoimmunity	129
A versatile residue numbering scheme for Nav and Cav channels	127
Voices: Challenges and opportunities in regulating the immune system	96
A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer	96
RENBP inhibition amplifies metabolic glycan labeling efficiency of antigen-presenting cells in vitro and in vivo	89
ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas	87
A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection	81
Acute pharmacological degradation of ERK5 does not inhibit cellular immune response or proliferation	79
Antisense-mediated senseful regulation of orchestrated metabolic response	77
Meet the Authors: Christopher R. Mansfield and Emily R. Derbyshire	77
New sheriff in town: Cyclic peptide inhibitors of a DUB module	75
Therapeutic potential of inhibiting the PI3Kγ complex for leukemia	75
Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1	74
Heterologous characterization of mechercharmycin A biosynthesis reveals alternative insights into post-translational modifications for RiPPs	71
2′-OH as a universal handle for studying intracellular RNAs	71
Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine	71
Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development	69
Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites	68
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance	65
Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples	64
Next steps for targeted protein degradation	64
Advances in spatial proteomics: Mapping proteome architecture from protein complexes to subcellular localizations	62
An interactive resource mapping the proteome and reactive cysteine landscape across the NCI-60 reveals cell and tissue-specific profiles	57
FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication	56
Meet the Authors: Harkamal S. Jhajj and Peter M. Tessier	55

Valence and avidity determine the agonistic activity of anti-TNFR2 nanobody fusion proteins	53
PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ	51
Catalytic spike antibodies: A new paradigm in neutralization	51
Beyond antibiotic resistance: The whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria	50
A complex puzzle: Regulation of SLFN12 RNase activity by phosphorylation	50
Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells	49
Meet the Cell Chemical Biology author and newest advisory board member: Marcus Conrad	49
Real-time non-invasive fluorescence imaging of gut commensal bacteria to detect dynamic changes in the microbiome of live mice	48
Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy	48
A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation	46
Target deconvolution with matrix-augmented pooling strategy reveals cell-specific drug-protein interactions	45
Mechanisms by which microbiome-derived metabolites exert their impacts on neurodegeneration	44
Metabolic tug-of-war: Microbial metabolism shapes colonization resistance against enteric pathogens	44
N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis	44
A double whammy for KEAP1	43
BLOC-1 and BORC: Complex regulators of endolysosomal dynamics	43
Visualizing Staphylococcus aureus pathogenic membrane modification within the host infection environment by multimodal imaging mass spectrometry	42
Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET	42