OOIR: Observatory of International Research

Papers

(The H4-Index of Bioactive Materials is 76. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Neonatal Fc receptor-targeted lignin-encapsulated porous silicon nanoparticles for enhanced cellular interactions and insulin permeation across the intestinal epithelium	346
Outside Front Cover	323
Microfluidic intestinal organoid-on-a-chip uncovers therapeutic targets by recapitulating oxygen dynamics of intestinal IR injury	293
Outside Front Cover	288
Thermodynamically stable ionic liquid microemulsions pioneer pathways for topical delivery and peptide application	222
Bioresponsive and immunotherapeutic nanomaterials to remodel tumor microenvironment for enhanced immune checkpoint blockade	217
Outside Front Cover	204
Degradation behavior of ZE21C magnesium alloy suture anchors and their effect on ligament-bone junction repair	194
Tellurium-driven maple leaf-shaped manganese nanotherapeutics reshape tumor microenvironment via chemical transition in situ to achieve highly efficient radioimmunotherapy of triple negative breast ca	194
A self-fused hydrogel for the treatment of glottic insufficiency through outstanding durability, extracellular matrix-inducing bioactivity and function preservation	191
Outside Front Cover	189
Nanomaterial-assisted theranosis of bone diseases	185
Outside Front Cover	156
A novel gatifloxacin-loaded intraocular lens for prophylaxis of postoperative endophthalmitis	155
Outside Front Cover	154
Sprayable nanomicelle hydrogels and inflammatory bowel disease patient cell chips for development of intestinal lesion-specific therapy	150
Decoupling the role of chemistry and microstructure in hMSCs response to an osteoinductive calcium phosphate ceramic	149
A deformable SIS/HA composite hydrogel coaxial scaffold promotes alveolar bone regeneration after tooth extraction	147
Enhancing bone regeneration through 3D printed biphasic calcium phosphate scaffolds featuring graded pore sizes	144
Establishing a cryopreserved biobank of living tumor tissues for drug sensitivity testing	144
NIR-II photo-accelerated polymer nanoparticles boost tumor immunotherapy via PD-L1 silencing and immunogenic cell death	139
A hydrogel spinal dural patch with potential anti-inflammatory, pain relieving and antibacterial effects	138
CXCR4-guided liposomes regulating hypoxic and immunosuppressive microenvironment for sorafenib-resistant tumor treatment	137
Dual stimuli-responsive polyurethane-based hydrogels as smart drug delivery carriers for the advanced treatment of chronic skin wounds	131
Design principles in mechanically adaptable biomaterials for repairing annulus fibrosus rupture: A review	126

A low dose cell therapy system for treating osteoarthritis: In vivo study and in vitro mechanistic investigations	125
“Slow walk” mimetic tensile loading maintains human meniscus tissue resident progenitor cells homeostasis in photocrosslinked gelatin hydrogel	123
Matrix from urine stem cells boosts tissue-specific stem cell mediated functional cartilage reconstruction	119
Tissue adhesive hemostatic microneedle arrays for rapid hemorrhage treatment	119
Platinum-crosslinking polymeric nanoparticle for synergetic chemoradiotherapy of nasopharyngeal carcinoma	114
Reprogramming macrophages via immune cell mobilized hydrogel microspheres for osteoarthritis treatments	114
Robust reactive oxygen species modulator hitchhiking yeast microcapsules for colitis alleviation by trilogically intestinal microenvironment renovation	114
CD301b+ macrophages mediate angiogenesis of calcium phosphate bioceramics by CaN/NFATc1/VEGF axis	113
Engineering the next generation of theranostic biomaterials with synthetic biology	112
Recent advances in engineering iron oxide nanoparticles for effective magnetic resonance imaging	111
Nanomotor-based H2S donor with mitochondrial targeting function for treatment of Parkinson's disease	110
Sialic acid-engineered mesoporous polydopamine nanoparticles loaded with SPIO and Fe3+ as a novel theranostic agent for T1/T2 dual-mode MRI-guided combined chemo-photothermal treatment of hepatic canc	108
Zwitterionic betaines over HEPES as the new generation biocompatible pH buffers for cell culture	107
Artificial cilia for soft and stable surface covalent immobilization of bone morphogenetic protein-2	104
Peroxidase-mimicking evodiamine/indocyanine green nanoliposomes for multimodal imaging-guided theranostics for oral squamous cell carcinoma	102
Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration	101
A multifunctional scaffold that promotes the scaffold-tissue interface integration and rescues the ROS microenvironment for repair of annulus fibrosus defects	98
A two-pronged approach to inhibit ferroptosis of MSCs caused by the iron overload in postmenopausal osteoporosis and promote osseointegration of titanium implant	98
Topical treatment of tyrosine kinase 2 inhibitor through borneol-embedded hydrogel: Evaluation for preventive, therapeutic, and Recurrent management of psoriasis	97
Encapsulation of lyophilized platelet-rich fibrin in alginate-hyaluronic acid hydrogel as a novel vascularized substitution for myocardial infarction	97
Covalent functionalization of decellularized tissues accelerates endothelialization	97
Unleashing the potential of extracellular vesicles for ulcerative colitis and Crohn's disease therapy	94
Upconversion nanoparticles regulated drug & gas dual-effective nanoplatform for the targeting cooperated therapy of thrombus and anticoagulation	94
Bioinspired supramolecular nanofiber hydrogel through self-assembly of biphenyl-tripeptide for tissue engineering	93
Wet tissue adhesive polymeric powder hydrogels for skeletal muscle regeneration	91
NIR-enhanced Pt single atom/g-C3N4 nanozymes as SOD/CAT mimics to rescue ATP energy crisis by regulating oxidative phosphorylation pathway for delaying osteoarthritis progression	91
Three-dimensional-engineered bioprinted in vitro human neural stem cell self-assembling culture model constructs of Alzheimer's disease	87
Modeling human hypertrophic scars with 3D preformed cellular aggregates bioprinting	86
In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles	85
Surface structure change properties: Auto-soft bionic fibrous membrane in reducing postoperative adhesion	85
MoS2-based nanocomposites for cancer diagnosis and therapy	85
Promoting chondrogenesis by targeted delivery to the degenerating cartilage in early treatment of osteoarthritis	84
A DNA tetrahedron-based nanosuit for efficient delivery of amifostine and multi-organ radioprotection	84
Amelioration of ligamentum flavum hypertrophy using umbilical cord mesenchymal stromal cell-derived extracellular vesicles	83
Liver tissue engineering using decellularized scaffolds: Current progress, challenges, and opportunities	83
In situ engineered magnesium alloy implant for preventing postsurgical tumor recurrence	83
Minimally invasive bioprinting for in situ liver regeneration	82
Collagen membrane functionalized with magnesium oxide via room-temperature atomic layer deposition promotes osteopromotive and antimicrobial properties	81
Simvastatin-hydroxyapatite coatings prevent biofilm formation and improve bone formation in implant-associated infections	81
Surface charge adaptive nitric oxide nanogenerator for enhanced photothermal eradication of drug-resistant biofilm infections	81
Outside Front Cover	81
Tailoring the multiscale mechanics of tunable decellularized extracellular matrix (dECM) for wound healing through immunomodulation	80
Piezoelectric hydrogel for treatment of periodontitis through bioenergetic activation	80
Alkaline activation of endogenous latent TGFβ1 by an injectable hydrogel directs cell homing for in situ complex tissue regeneration	80
Sutureless vascular anastomotic approaches and their potential impacts	79
Cubic multi-ions-doped Na2TiO3 nanorod-like coatings: Structure-stable, highly efficient platform for ions-exchanged release to immunomodulatory promotion on vascularized bone apposition	79
Robust genome and RNA editing via CRISPR nucleases in PiggyBac systems	78
Nanostructured polyvinylpyrrolidone-curcumin conjugates allowed for kidney-targeted treatment of cisplatin induced acute kidney injury	77
Scalable fabrication, compartmentalization and applications of living microtissues	77
Biocompatibility and degradation comparisons of four biodegradable copolymeric osteosynthesis systems used in maxillofacial surgery: A goat model with four years follow-up	76

Polymersome-mediated cytosolic delivery of cyclic dinucleotide STING agonist enhances tumor immunotherapy