JACC-Basic to Translational Science

Article	Citations
Recognizing Early Career Translational Investigators	120
Editorial Board	103
A Potential New Therapeutic Direction for Fibrosis in the Injured Heart Orchestrated by Cardiac MSCs	83
Electroanatomical Navigation to Minimize Contrast Medium or X-Rays During Stenting	74
PD-1 Checkmate and the 2-Edged Sword of the Immune System	73
New Insights Into the Role of GSK-3 in the Regulation of Human Cardiac Electrophysiology	71
FULL ISSUE PDF	65
Is Laser Doppler Perfusion Imaging Truly a “Gold Standard” for Preclinical Peripheral Artery Disease Research?	64
Mitochondrial DNA in Uremia and New Targets to Treat Myocardial Hypertrophy in the Cardiorenal Syndrome	56
Reducing Plasma Factor XI Concentration With siRNA Technology	53
Validation of a Novel Renal Denervation System With Cryoablation	49
Right Heart Failure in Mice Upon Pressure Overload Is Promoted by Mitochondrial Oxidative Stress	48
CXC-Chemokine-Receptor-Type-5 Expression on Circulating Naive B Cells Predicts Improvement After Cardiac Resynchronization Therapy	47
Targeting Syntaxin 17 to Improve Mitophagy in Heart Failure	46
Is it Time to Abandon the Use of P-Values in Early Phase Translational Trials: Why (Effect) Size Matters	46
When Off-Target Is the Target	44
Reading a Good Transcript Soothes MYZAPed Heart	42
Full Issue PDF	40
Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model Induced by Bilateral Pulmonary Vein Banding	39
JACC: Basic to Translational Science 2016-2025	39
Low-Grade Inflammation in Long COVID Syndrome Sustains a Persistent Platelet Activation Associated With Lung Impairment	37
Unveiling the PGAM5-ANGPTL3 Axis	37
1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model	36
H2 Inhibits the Formation of Neutrophil Extracellular Traps	35
Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome	35

Addressing the Reproducibility Crisis in Science	34
New Drug-Coated Balloons on the Horizon	34
Full Issue PDF	34
Antibody Matrimony in a Duel of Hearts	32
ApoM Activates Autophagy and Suppresses Lyosomal Lethargy to Combat Doxorubicin Cardiomyopathy	32
Is Endogenous Fibrinolysis a Major Player in Occurrence of Atherothrombotic Events Following Acute Myocardial Infarction?	31
Recognizing Early Career Translational Investigators	31
The Reduction of COMP Serves as a Predictor for Warning of Aortic Dissection Progression	31
6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model	30
Therapeutic Efficacy of a Novel Pharmacologic GRK2 Inhibitor in Multiple Animal Models of Heart Failure	30
SIRT1 Ameliorates Lamin A/C Deficiency-Induced Cardiac Dysfunction by Promoting Mitochondrial Bioenergetics	30
Cardiomyocyte Alpha-1A Adrenergic Receptors Mitigate Postinfarct Remodeling and Mortality by Constraining Necroptosis	30
Full Issue PDF	30
Characterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart	30
PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction	30
TCF7L1 Accelerates Smooth Muscle Cell Phenotypic Switching and Aggravates Abdominal Aortic Aneurysms	29
Inflammasome Signaling, Thromboinflammation, and Venous Thromboembolism	29
Full Issue Pdf	28
Reply	28
Editorial Board	28
Interferon Interrupted	27
Exosome-Mediated Angiogenesis Underlies LVAD-Induced Bleeding in Patients With End-Stage Heart Failure	26
The Farm to Table HFpEF Kitchen	26
Reply	26
Soluble Programmed Death-1 Predicts Clinical Outcome After STEMI	26
Determinants of Endogenous Fibrinolysis in Whole Blood Under High Shear in Patients With Myocardial Infarction	25
Epigenetic Regulation of Heart-ECHS	25
Red Blood Cell-Mediated Cardioprotection Is Impaired in ST-Segment Elevation Myocardial Infarction Patients With Anemia	24
From Colon to Aortic Aneurysm: Trek of the Treg	24
C-Type Natriuretic Peptide in Essential Hypertension	24
Phosphoglycerate Mutase 5 Is Important Mediator for Instigating Arterial Lipid Accumulation and Aggravating Atherosclerosis	24
Nitric Oxide Releasing Nanomaterials for Cardiovascular Applications	24
Shear-Thinning Hydrogel for Delayed Delivery of a Small Molecule Metalloproteinase Inhibitor Attenuates Myocardial Infarction Remodeling	24
Lower Extremity Lymphatic Flow/Drainage Assessment by Indocyanine Green Fluorescent Lymphography in Heart Failure Patients	23
Editorial Board	23
Endocardial Fibrosis Elastosis	23
Pulsatile ECMO	22
ATP-Citrate Lyase in Heart Failure	21
A Differentiated Approach Delivering Targeted Thrombectomy for VTE	21
Large Animal Models for Transcatheter Heart Valve Prosthesis Development	21
Regions of Highly Recurrent Electrogram Morphology With Low Cycle Length Reflect Substrate for Atrial Fibrillation	21
Should All Translational Scientists Be Swifties?	21
Inhibiting Serotonin to Treat Pulmonary Arterial Hypertension	21
When Facts Become Forbidden	21
A Novel LncRNA SNHG3 Promotes Osteoblast Differentiation Through BMP2 Upregulation in Aortic Valve Calcification	21
From Risk to Remedy?	20
Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules	20
Glucagon-Like Peptide-1 Receptor Regulates Thromboxane-Induced Human Platelet Activation	19
Fir(e)ing the Rhythm	19
TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis	19

Full Issue Pdf	18
Proteomics of Large Artery Stiffness	18
Full Issue PDF	18
Noninvasive Cardiovascular Imaging in Preclinical Research	18
Full Issue PDF	18
Full Issue Pdf	17
Full Issue PDF	17
Reduced Proteolytic Cleavage of von Willebrand Factor Leads to Aortic Valve Stenosis and Load-Dependent Ventricular Remodeling	17
Full Issue PDF	17
JACC: Basic to Translational Science Top Reviewers 2022: With Appreciation and Gratitude	17
Full Issue PDF	16
Pleiotropic, Cellular Effects of Rivaroxaban on Autophagy Explain Atheroprotective Effects	16
The Impact of Semaglutide on Cardiac Mass and Function Requires Further Investigation	16
The Virtual Patient Simulator	16
Pulsatile Ventricular Assist Platform	16
A Novel Pathway of Platelet Activation in ACS Mediated by LL-37 Immunoglobulin G Autoantibody Immune Complexes	15
Acute Glycogen Synthase Kinase-3 Inhibition Modulates Human Cardiac Conduction	15
The Past, Present, and Promising Future of Direct Cardiac Compression Devices	15
Real-Time Revolution	15
Tissue Engineered Vascular Grafts	15
Ticagrelor Antibiotic Effect	15
Propionate Alleviates Abdominal Aortic Aneurysm by Modulating Colonic Regulatory T-Cell Expansion and Recirculation	14
CD14 Blockade Modulates Macrophage-Mediated Immunological Injury in a Translational Model of Reperfused ST-Segment Elevation Myocardial Infarction	14
Reassessing the Mechanisms of PLN-R14del Cardiomyopathy	14
Cardiac Spinal Afferent Denervation Attenuates Renal Dysfunction in Rats With Cardiorenal Syndrome Type 2	14
Neuregulin-1β Improves Uremic Cardiomyopathy and Renal Dysfunction in Rats	14
IL-6 Inhibitors and TNF Inhibitors	14
Full Issue PDF	13
Where Comity in Science Goes to Die	13
Reverse Translation of Pericardial Access	13
Editorial Board	13
Editorial Board	13
Introducing the 2024 Transcatheter Cardiovascular Therapeutics (TCT) Shark Tank Presentations	13
Small Molecule Activators of Mitochondrial Fusion Prevent Congenital Heart Defects Induced by Maternal Diabetes	13
Synbiotics and Gut-Heart Axis in Cardiometabolic Disease	12
Towards Metabolomic-Based Precision Approaches for Classifying and Treating Heart Failure	12
Quality Over Quantity	12
TIMD4hiMHCⅡhi Macrophages Preserve Heart Function Through Retnla	12
Partial Heart Transplant Growth and Hemodynamic Function in Piglets	12
Structural and Functional Adaptations to Exercise Training	12
Targeting Myocardial Mitochondria-STING-Polyamine Axis Prevents Cardiac Hypertrophy in Chronic Kidney Disease	12
FNDC4 Prevents Aging-Related Cardiac Dysfunction	12
Autonomic Modulation of Atrial Fibrillation	11
Mesenchymal Stromal Cell Delivery Via Cardiopulmonary Bypass Provides Neuroprotection in a Juvenile Porcine Model	11
With No Lysine Kinase 1 Promotes Metabolic Derangements and RV Dysfunction in Pulmonary Arterial Hypertension	11
Editorial Board	11
Editorial Board	11
Experimental Models of Hypertrophic Cardiomyopathy	11
GLP-1 Receptor Agonists, the Holy Grail Preventing Atrial Fibrillation in Patients With T2D?	11
Full Issue PDF	11
Turn(over) the Page	11
JACC: Basic to Translational Science 2024 Thomas Force Young Investigator Award Winner	11
Charting New Real Estate	11
Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury	11
A Cardiac Amino-Terminal GRK2 Peptide Inhibits Maladaptive Adipocyte Hypertrophy and Insulin Resistance During Diet-Induced Obesity	11
Paradoxical Effect of Caloric Restriction on Overload-Induced Muscle Growth in Diastolic Heart Failure	10
Atrial Metabolic Stress	10
Left Atrial Glucose Metabolism Evaluation by 18F-FDG-PET in Persistent Atrial Fibrillation and in Sinus Rhythm	10
Who Should Be Accountable for Scientific Accountability?	10
Recognizing Early Career Translational Investigators	10
Remembering Ada L. Steininger	10
Shielding the Heart	10
Tit for TAK1	10
Recurrent Adrenergic Stress Provokes Persistent Myocarditis in PD-1–Deficient Mice	10
Myocardial Infarction Suppresses Protein Synthesis and Causes Decoupling of Transcription and Translation	10
Publisher's Note	10
Full Issue PDF	10
In Vivo Efficacy of an Adhesive Bioresorbable Patch to Treat Aortic Dissections	10
Inhibition of Factor XI Using RBD4059	10
Continuous Monitoring of Blood Pressure and Vascular Hemodynamic Properties With Miniature Extravascular Hall-Based Magnetic Sensor	10
BAG3 in the Heart	9
The Cardiac Circadian Clock	9
Deficiency of GDF-11 Accelerates TAC-Induced Heart Failure by Impairing Cardiac Angiogenesis	9
Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction	9
Effect of Semaglutide on Epicardial Adipogenesis and hiPSC-Atrial Cardiomyocytes New Hope in Targeting Epicardial Adipose Tissue	9
Negative Impact of TET2 Mutations on Long-Term Survival After Transcatheter Aortic Valve Replacement	9
Differential BMP Signaling Mediates the Interplay Between Genetics and Leaflet Numbers in Aortic Valve Calcification	9
Intravascular Lithotripsy on Concentric, Eccentric, and Extrastent Calcium	9
Minimally Invasive Aortic Regurgitation Surgery	9
New Insights in the Pathology of Chronic Thromboembolic Pulmonary Hypertension	8

The Imperative to Enhance Cost-Effectiveness for Cardiovascular Therapeutic Development	8
High Maternal Glycine Levels Increase the Risk of Developing Atrial Septal Defect in the Offspring	8
Editorial Board	8
Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension	8
Full Issue PDF	8
New Insights Into the Therapy for Lamin-Associated Dilated Cardiomyopathy	8
Erythrocytes Induce Vascular Dysfunction in COVID-19	8
Full Issue PDF	8
Introducing the 2024 THT Shark Tank Edition of JACC: Basic to Translational Science	8
Cardiac Adrenergic Activation in Heart Failure With Preserved Ejection Fraction	8
Cardiovascular Disease in Duchenne Muscular Dystrophy	8
Platelets	8
A (Alpha1-Adrenergic Receptors), B (Blocking Alpha1-Adrenergic Receptors), C (Catecholamines)	8
Myocardial Infarction Platelet Gene Expression Signatures in Women	8
Parkin Insufficiency Accentuates High-Fat Diet–Induced Cardiac Remodeling and Contractile Dysfunction Through VDAC1-Mediated Mitochondrial Ca2+ Overload	8
Will Gene Editing Orphanize Rare Diseases?	7
Are 3 Aorta Pumps Better Than 1 Transaortic to Preserve Von Willebrand Factor?	7
Platelet-Derived Growth Factors	7
The Antioxidant Vitamin B12 Analogue Cobinamide as a Treatment for Marfan Syndrome	7
Full Issue PDF	7
The Quest for an Early Marker of Anthracycline-Induced Cardiotoxicity	7
Full Issue PDF	7
Proteome-Wide Genetic Investigation of Large Artery Stiffness	7
Editorial Board	7
JACC Journals’ Pathway Forward With AI Tools	7
Editorial Board	7
Translating Imaging Into 3D Printed Cardiovascular Phantoms	7
Low-Grade Inflammation	7
Intrinsic and Extrinsic Contributors to the Cardiac Benefits of Exercise	7
Mitophagy Regulators as Novel Targets in Sepsis-Induced Myocardial Dysfunction	7
PCSK9 Inhibition	7
Controlled Right Ventricular Pressure Overload Can Rescue Left Ventricular Dysfunction by Promoting Biventricular Adaptive Hypertrophy	7
Editorial Board	7
Heart Failure Solutions	7
Recognizing Early Career Translational Investigators	7
Red Blood Cell Transfusion and Cardiac Surgery–Associated Acute Kidney Injury	6
A Novel Device for Tricuspid Regurgitation Reduction Featuring 3-Dimensional Leaflet and Atraumatic Anchor	6
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy	6
Estrogen Influences Human Microvascular Endothelial Function Via Sex-Specific Regulation of Sphingolipids	6
Editorial Board	6
Transvalvular Unloading Mitigates Ventricular Injury Due to Venoarterial Extracorporeal Membrane Oxygenation in Acute Myocardial Infarction	6
The Emerging Role of Circular RNAs in Cardio-Oncology	6
Associations of Epigenetic Age Acceleration With CVD Risks Across the Lifespan	6
Clinical Phenotypes of Heart Failure With Preserved Ejection Fraction to Select Preclinical Animal Models	6
Deep Image Segmentation for Cardiomyocyte Proliferation	6
Deleterious Anti-Inflammatory Macrophage Recruitment in Early Post-Infarction Phase	6
Decreased FAM13B Expression Increases Atrial Fibrillation Susceptibility by Regulating Sodium Current and Calcium Handling	6
Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy	6
Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes	6
The Pathology of Primary Mitral Regurgitation	6
Homophilic Interaction Between Transmembrane-JAM-A and Soluble JAM-A Regulates Thrombo-Inflammation	6
Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF	5
Cardiac Xenotransplantation	5
Editorial Board	5
Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure	5
Caloric Restriction Rejuvenates Skeletal Muscle Growth in Heart Failure With Preserved Ejection Fraction	5
The Thomas Force Young Investigator Award	5
The Enigmata of Cardioprotection With SGLT2 Inhibition	5
Maintaining Success for Patients With Dilated Cardiomyopathy and Remission of Heart Failure	5
Correction	5
Highlighting the Unique Challenges Presented by Device Trials in Heart Failure	5
Tie2-Cre–Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury	5
Mitochondrial Calcium Flux—Friend or Foe in Chronic Heart Failure?	5
Cardiovascular Research in Friedreich Ataxia	5
A New Ex Vivo Model to Study Cardiac Fibrosis in Whole Mouse Hearts	5
INKing the Cardiotoxicity Out of Doxorubicin	5
Vagus Nerve Stimulation for Myocardial Ischemia	5
Dysregulation of IL-6/MCP-1/STAT3 Axis	5
Mitochondrial Targeted Therapies to Prevent Maternal Diabetes–Induced Congenital Heart Defects	5
Correction	5
New Insights in Peripheral Arterial Disease	5
Exploring Mechanisms of Pulmonary Artery Banding in a Rat Model of Dilated Cardiomyopathy	5
Natriuretic Peptides and Metabolic Hypertension	5
Abnormal Flow Conditions Promote Endocardial Fibroelastosis Via Endothelial-to-Mesenchymal Transition, Which Is Responsive to Losartan Treatment	5
In Memory of Dr Gary D. Lopaschuk, PhD (1955–2025)	5
Focusing on the Native Matrix Proteins in Calcific Aortic Valve Stenosis	5
Clonal Hematopoiesis and Transcatheter Aortic Valve Replacement	5
Cardiac TRPM7 Causes Diabetic Heart Failure With Preserved Ejection Fraction	5
Editorial Board	5
Electrogram Morphology Recurrence	5
Full Issue PDF	4
Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload	4
Precision Medicine	4
The Technique of Permanent Pericardial Catheter in Mice	4
“Circulating Inflammation” and the Plasma Proteome in Heart Failure With Preserved Ejection Fraction	4
Making Science Fun Again	4
JACC: Basic to Translational Science 2022 Thomas Force Young Investigator Award Winner	4
Full Issue PDF	4
Cardiac Xenotransplantation	4
Small Extracellular Vesicles in the Pericardium Modulate Macrophage Immunophenotype in Coronary Artery Disease	4
Recognizing Early Career Translational Investigators	4
Empowering the Future: The Importance of Recognizing Early Career Scientists in JACC: Basic to Translational Science	4
PCSK9, A Promising Novel Target for Age-Related Cardiovascular Dysfunction	4
Full Issue PDF	4
Parkin Controls Cardiac Function in Obesity by Regulating Mitochondrial Calcium Uptake	4