JACC-Basic to Translational Science

Article	Citations
PD-1 Checkmate and the 2-Edged Sword of the Immune System	113
New Insights Into the Role of GSK-3 in the Regulation of Human Cardiac Electrophysiology	98
FULL ISSUE PDF	79
Editorial Board	72
A Potential New Therapeutic Direction for Fibrosis in the Injured Heart Orchestrated by Cardiac MSCs	72
Recognizing Early Career Translational Investigators	70
Electroanatomical Navigation to Minimize Contrast Medium or X-Rays During Stenting	65
Mitochondrial DNA in Uremia and New Targets to Treat Myocardial Hypertrophy in the Cardiorenal Syndrome	58
Is Laser Doppler Perfusion Imaging Truly a “Gold Standard” for Preclinical Peripheral Artery Disease Research?	54
Targeting Syntaxin 17 to Improve Mitophagy in Heart Failure	48
Full Issue PDF	47
CXC-Chemokine-Receptor-Type-5 Expression on Circulating Naive B Cells Predicts Improvement After Cardiac Resynchronization Therapy	46
Right Heart Failure in Mice Upon Pressure Overload Is Promoted by Mitochondrial Oxidative Stress	46
When Off-Target Is the Target	41
Low-Grade Inflammation in Long COVID Syndrome Sustains a Persistent Platelet Activation Associated With Lung Impairment	41
Reading a Good Transcript Soothes MYZAPed Heart	41
Reducing Plasma Factor XI Concentration With siRNA Technology	39
Unveiling the PGAM5-ANGPTL3 Axis	39
1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model	38
Is it Time to Abandon the Use of P-Values in Early Phase Translational Trials: Why (Effect) Size Matters	38
Validation of a Novel Renal Denervation System With Cryoablation	37
Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model Induced by Bilateral Pulmonary Vein Banding	36
JACC: Basic to Translational Science 2016-2025	35
Full Issue PDF	32
Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome	32

H2 Inhibits the Formation of Neutrophil Extracellular Traps	32
New Drug-Coated Balloons on the Horizon	31
Therapeutic Efficacy of a Novel Pharmacologic GRK2 Inhibitor in Multiple Animal Models of Heart Failure	31
Is Endogenous Fibrinolysis a Major Player in Occurrence of Atherothrombotic Events Following Acute Myocardial Infarction?	30
Recognizing Early Career Translational Investigators	30
Can We Use Viscoelastic Testing to Evaluate Microvascular Dysfunction in Acute Myocardial Infarction?	29
Inflammasome Signaling, Thromboinflammation, and Venous Thromboembolism	29
Characterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart	29
Addressing the Reproducibility Crisis in Science	28
TCF7L1 Accelerates Smooth Muscle Cell Phenotypic Switching and Aggravates Abdominal Aortic Aneurysms	28
SIRT1 Ameliorates Lamin A/C Deficiency-Induced Cardiac Dysfunction by Promoting Mitochondrial Bioenergetics	28
Antibody Matrimony in a Duel of Hearts	28
ApoM Activates Autophagy and Suppresses Lyosomal Lethargy to Combat Doxorubicin Cardiomyopathy	28
6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model	27
Cardiomyocyte Alpha-1A Adrenergic Receptors Mitigate Postinfarct Remodeling and Mortality by Constraining Necroptosis	27
PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction	26
The Reduction of COMP Serves as a Predictor for Warning of Aortic Dissection Progression	26
Full Issue PDF	26
Reply	25
Interferon Interrupted	25
Exosome-Mediated Angiogenesis Underlies LVAD-Induced Bleeding in Patients With End-Stage Heart Failure	25
Full Issue Pdf	25
A Novel LncRNA SNHG3 Promotes Osteoblast Differentiation Through BMP2 Upregulation in Aortic Valve Calcification	25
Editorial Board	24
Determinants of Endogenous Fibrinolysis in Whole Blood Under High Shear in Patients With Myocardial Infarction	24
Soluble Programmed Death-1 Predicts Clinical Outcome After STEMI	24
Epigenetic Regulation of Heart-ECHS	24
The Farm to Table HFpEF Kitchen	24
A Differentiated Approach Delivering Targeted Thrombectomy for VTE	23
When Facts Become Forbidden	23
Reply	23
Should All Translational Scientists Be Swifties?	23
From Colon to Aortic Aneurysm: Trek of the Treg	23
C-Type Natriuretic Peptide in Essential Hypertension	22
Pulsatile ECMO	22
Phosphoglycerate Mutase 5 Is Important Mediator for Instigating Arterial Lipid Accumulation and Aggravating Atherosclerosis	21
Large Animal Models for Transcatheter Heart Valve Prosthesis Development	21
Editorial Board	21
Inhibiting Serotonin to Treat Pulmonary Arterial Hypertension	21
Lower Extremity Lymphatic Flow/Drainage Assessment by Indocyanine Green Fluorescent Lymphography in Heart Failure Patients	20
TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis	20
Fir(e)ing the Rhythm	20
Regions of Highly Recurrent Electrogram Morphology With Low Cycle Length Reflect Substrate for Atrial Fibrillation	20
ATP-Citrate Lyase in Heart Failure	20
Glucagon-Like Peptide-1 Receptor Regulates Thromboxane-Induced Human Platelet Activation	19
Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules	18
Endocardial Fibrosis Elastosis	18
Shear-Thinning Hydrogel for Delayed Delivery of a Small Molecule Metalloproteinase Inhibitor Attenuates Myocardial Infarction Remodeling	18
Nitric Oxide Releasing Nanomaterials for Cardiovascular Applications	17
Full Issue PDF	17

Red Blood Cell-Mediated Cardioprotection Is Impaired in ST-Segment Elevation Myocardial Infarction Patients With Anemia	17
Full Issue PDF	17
Full Issue PDF	16
Noninvasive Cardiovascular Imaging in Preclinical Research	16
Reduced Proteolytic Cleavage of von Willebrand Factor Leads to Aortic Valve Stenosis and Load-Dependent Ventricular Remodeling	16
Full Issue Pdf	16
Proteomics of Large Artery Stiffness	16
JACC: Basic to Translational Science Top Reviewers 2022: With Appreciation and Gratitude	15
Full Issue Pdf	15
Pleiotropic, Cellular Effects of Rivaroxaban on Autophagy Explain Atheroprotective Effects	15
Ticagrelor Antibiotic Effect	15
Full Issue PDF	15
Full Issue PDF	15
The Virtual Patient Simulator	15
Pulsatile Ventricular Assist Platform	15
Real-Time Revolution	15
The Impact of Semaglutide on Cardiac Mass and Function Requires Further Investigation	15
A Novel Pathway of Platelet Activation in ACS Mediated by LL-37 Immunoglobulin G Autoantibody Immune Complexes	15
Cardiac Spinal Afferent Denervation Attenuates Renal Dysfunction in Rats With Cardiorenal Syndrome Type 2	14
Propionate Alleviates Abdominal Aortic Aneurysm by Modulating Colonic Regulatory T-Cell Expansion and Recirculation	14
Acute Glycogen Synthase Kinase-3 Inhibition Modulates Human Cardiac Conduction	14
The Past, Present, and Promising Future of Direct Cardiac Compression Devices	14
Tissue Engineered Vascular Grafts	13
Neuregulin-1β Improves Uremic Cardiomyopathy and Renal Dysfunction in Rats	13
Reassessing the Mechanisms of PLN-R14del Cardiomyopathy	13
Small Molecule Activators of Mitochondrial Fusion Prevent Congenital Heart Defects Induced by Maternal Diabetes	13
IL-6 Inhibitors and TNF Inhibitors	13
Editorial Board	13
Introducing the 2024 Transcatheter Cardiovascular Therapeutics (TCT) Shark Tank Presentations	12
GLP-1 Receptor Agonists, the Holy Grail Preventing Atrial Fibrillation in Patients With T2D?	12
Full Issue PDF	12
Where Comity in Science Goes to Die	12
Reverse Translation of Pericardial Access	12
Synbiotics and Gut-Heart Axis in Cardiometabolic Disease	12
Editorial Board	12
With No Lysine Kinase 1 Promotes Metabolic Derangements and RV Dysfunction in Pulmonary Arterial Hypertension	11
Targeting Myocardial Mitochondria-STING-Polyamine Axis Prevents Cardiac Hypertrophy in Chronic Kidney Disease	11
Autonomic Modulation of Atrial Fibrillation	11
Mesenchymal Stromal Cell Delivery Via Cardiopulmonary Bypass Provides Neuroprotection in a Juvenile Porcine Model	11
A Cardiac Amino-Terminal GRK2 Peptide Inhibits Maladaptive Adipocyte Hypertrophy and Insulin Resistance During Diet-Induced Obesity	11
Autophagy Signaling and Oxidative Stress in Thoracic Aortic Aneurysms	11
Structural and Functional Adaptations to Exercise Training	11
Experimental Models of Hypertrophic Cardiomyopathy	10
FNDC4 Prevents Aging-Related Cardiac Dysfunction	10
Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury	10
JACC: Basic to Translational Science 2024 Thomas Force Young Investigator Award Winner	10
Partial Heart Transplant Growth and Hemodynamic Function in Piglets	10
Charting New Real Estate	10
Turn(over) the Page	10
Editorial Board	10
Quality Over Quantity	10
TIMD4hiMHCⅡhi Macrophages Preserve Heart Function Through Retnla	10
Deficiency of GDF-11 Accelerates TAC-Induced Heart Failure by Impairing Cardiac Angiogenesis	9
Full Issue PDF	9
Atrial Metabolic Stress	9
Recurrent Adrenergic Stress Provokes Persistent Myocarditis in PD-1–Deficient Mice	9
Towards Metabolomic-Based Precision Approaches for Classifying and Treating Heart Failure	9
Intravascular Lithotripsy on Concentric, Eccentric, and Extrastent Calcium	9
Differential BMP Signaling Mediates the Interplay Between Genetics and Leaflet Numbers in Aortic Valve Calcification	9
In Vivo Efficacy of an Adhesive Bioresorbable Patch to Treat Aortic Dissections	9
Shielding the Heart	9
Editorial Board	9
Remembering Ada L. Steininger	9
Paradoxical Effect of Caloric Restriction on Overload-Induced Muscle Growth in Diastolic Heart Failure	9
Tit for TAK1	9
Full Issue PDF	9
Negative Impact of TET2 Mutations on Long-Term Survival After Transcatheter Aortic Valve Replacement	8
Continuous Monitoring of Blood Pressure and Vascular Hemodynamic Properties With Miniature Extravascular Hall-Based Magnetic Sensor	8
BAG3 in the Heart	8
Myocardial Infarction Platelet Gene Expression Signatures in Women	8
A (Alpha1-Adrenergic Receptors), B (Blocking Alpha1-Adrenergic Receptors), C (Catecholamines)	8
Publisher's Note	8
Inhibition of Factor XI Using RBD4059	8
Who Should Be Accountable for Scientific Accountability?	8
Left Atrial Glucose Metabolism Evaluation by 18F-FDG-PET in Persistent Atrial Fibrillation and in Sinus Rhythm	8
Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction	8
Full Issue PDF	8
Parkin Insufficiency Accentuates High-Fat Diet–Induced Cardiac Remodeling and Contractile Dysfunction Through VDAC1-Mediated Mitochondrial Ca2+ Overload	8
Myocardial Infarction Suppresses Protein Synthesis and Causes Decoupling of Transcription and Translation	8
The Cardiac Circadian Clock	8

Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension	8
Editorial Board	8
Full Issue PDF	7
The Imperative to Enhance Cost-Effectiveness for Cardiovascular Therapeutic Development	7
Low-Grade Inflammation	7
Cardiac Adrenergic Activation in Heart Failure With Preserved Ejection Fraction	7
Platelet-Derived Growth Factors	7
Platelets	7
Introducing the 2024 THT Shark Tank Edition of JACC: Basic to Translational Science	7
New Insights Into the Therapy for Lamin-Associated Dilated Cardiomyopathy	7
Translating Imaging Into 3D Printed Cardiovascular Phantoms	7
Editorial Board	7
Full Issue PDF	7
PCSK9 Inhibition	7
JACC Journals’ Pathway Forward With AI Tools	7
Intrinsic and Extrinsic Contributors to the Cardiac Benefits of Exercise	7
The Quest for an Early Marker of Anthracycline-Induced Cardiotoxicity	7
Erythrocytes Induce Vascular Dysfunction in COVID-19	7
High Maternal Glycine Levels Increase the Risk of Developing Atrial Septal Defect in the Offspring	7
In the Ongoing Conflict Between Ideology and Immunity, Which Side Will Protect the Children From Post-Acute Sequelae of COVID-19?	7
New Insights in the Pathology of Chronic Thromboembolic Pulmonary Hypertension	7
Cardiovascular Disease in Duchenne Muscular Dystrophy	7
Are 3 Aorta Pumps Better Than 1 Transaortic to Preserve Von Willebrand Factor?	6
Heart Failure Solutions	6
The Antioxidant Vitamin B12 Analogue Cobinamide as a Treatment for Marfan Syndrome	6
Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy	6
Editorial Board	6
Proteome-Wide Genetic Investigation of Large Artery Stiffness	6
Red Blood Cell Transfusion and Cardiac Surgery–Associated Acute Kidney Injury	6
Editorial Board	6
Will Gene Editing Orphanize Rare Diseases?	6
Full Issue PDF	6
Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes	6
Deleterious Anti-Inflammatory Macrophage Recruitment in Early Post-Infarction Phase	6
Decreased FAM13B Expression Increases Atrial Fibrillation Susceptibility by Regulating Sodium Current and Calcium Handling	5
Vagus Nerve Stimulation for Myocardial Ischemia	5
Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF	5
Tie2-Cre–Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury	5
In Memory of Dr Gary D. Lopaschuk, PhD (1955–2025)	5
Editorial Board	5
Transvalvular Unloading Mitigates Ventricular Injury Due to Venoarterial Extracorporeal Membrane Oxygenation in Acute Myocardial Infarction	5
Homophilic Interaction Between Transmembrane-JAM-A and Soluble JAM-A Regulates Thrombo-Inflammation	5
The Emerging Role of Circular RNAs in Cardio-Oncology	5
Clonal Hematopoiesis and Transcatheter Aortic Valve Replacement	5
Dysregulation of IL-6/MCP-1/STAT3 Axis	5
A New Ex Vivo Model to Study Cardiac Fibrosis in Whole Mouse Hearts	5
Maintaining Success for Patients With Dilated Cardiomyopathy and Remission of Heart Failure	5
Mitochondrial Targeted Therapies to Prevent Maternal Diabetes–Induced Congenital Heart Defects	5
Clinical Phenotypes of Heart Failure With Preserved Ejection Fraction to Select Preclinical Animal Models	5
Controlled Right Ventricular Pressure Overload Can Rescue Left Ventricular Dysfunction by Promoting Biventricular Adaptive Hypertrophy	5
The Pathology of Primary Mitral Regurgitation	5
Associations of Epigenetic Age Acceleration With CVD Risks Across the Lifespan	5
The Thomas Force Young Investigator Award	5
Deep Image Segmentation for Cardiomyocyte Proliferation	5
The Enigmata of Cardioprotection With SGLT2 Inhibition	5
Caloric Restriction Rejuvenates Skeletal Muscle Growth in Heart Failure With Preserved Ejection Fraction	5
INKing the Cardiotoxicity Out of Doxorubicin	5
Natriuretic Peptides and Metabolic Hypertension	5
Mitophagy Regulators as Novel Targets in Sepsis-Induced Myocardial Dysfunction	5
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy	5
A Novel Device for Tricuspid Regurgitation Reduction Featuring 3-Dimensional Leaflet and Atraumatic Anchor	5
Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure	4
Fake It Till You Make It	4
Mitochondrial Calcium Flux—Friend or Foe in Chronic Heart Failure?	4
Liraglutide Lowers Endothelial Vascular Cell Adhesion Molecule-1 in Murine Atherosclerosis Independent of Glucose Levels	4
Small Extracellular Vesicles in the Pericardium Modulate Macrophage Immunophenotype in Coronary Artery Disease	4
Full Issue PDF	4
DCBL2 Deficiency Contributes to Aortic Stenosis via Increased BMP2 Signaling	4
Early Life Cardiovascular Risk Factors and Midlife Epigenetic Aging	4
Cardiac Xenotransplantation	4
Role of Oxidative Stress and Autophagy in Thoracic Aortic Aneurysms	4
Exploring Mechanisms of Pulmonary Artery Banding in a Rat Model of Dilated Cardiomyopathy	4
Editorial Board	4
The Technique of Permanent Pericardial Catheter in Mice	4
Serum Anti-Heart and Antinuclear Autoantibodies Are Independent Predictors of Response to Immunosuppressive Therapy in Autoimmune Biopsy-Proven Inflammatory Cardiomyopathy	4
Cardiac Xenotransplantation	4
How Clonal Hematopoiesis Can Predict Treatment Response in Patients With Dilated Cardiomyopathy	4
Translating Translation	4
Editorial Board	4
Correction	4
Focusing on the Native Matrix Proteins in Calcific Aortic Valve Stenosis	4
Cardiovascular Research in Friedreich Ataxia	4
Abnormal Flow Conditions Promote Endocardial Fibroelastosis Via Endothelial-to-Mesenchymal Transition, Which Is Responsive to Losartan Treatment	4
Highlighting the Unique Challenges Presented by Device Trials in Heart Failure	4
Cardiac Gene Therapy With Relaxin Receptor 1 Overexpression Protects Against Acute Myocardial Infarction	4
Inflammatory Signature of Human Hypertension	4
Therapeutics That Promote Sympathetic Reinnervation Modulate the Inflammatory Response After Myocardial Infarction	4
Revitalizing Innovation	4
Correction	4
Electrogram Morphology Recurrence	4
New Insights in Peripheral Arterial Disease	4
Cardiac TRPM7 Causes Diabetic Heart Failure With Preserved Ejection Fraction	4
Clustering of Cardiac Transcriptome Profiles Reveals Unique	3
Recent Pathophysiological Insights Are Advancing the Treatment of Venous Thromboembolism	3
Transcriptomic Signatures of Calcific Aortic Valve Stenosis Severity in Human Tricuspid and Bicuspid Aortic Valves	3