JACC-Basic to Translational Science

Papers
(The TQCC of JACC-Basic to Translational Science is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
HIF-1α Cardioprotection in COVID-19 Patients124
Mutations of Splicing Regulator RBM20 in Atrial Fibrillation89
Anemia, Increased Shear Stress, and the Progression of Aortic Stenosis84
Comprehensive RV Hemodynamic Assessment With Pressure-Volume Analysis During Impella Support83
Cardiac Lymphatic Insufficiency Leads to Diastolic Dysfunction Via Myocardial Morphologic Change69
Cardiac GRK2 and the Communicative Axis Between Heart and Fat69
Renal Dysfunction in Heart Failure65
Editorial Board61
Cardioprotection Achieved Through Overexpression of Relaxin Receptors60
Full Issue Pdf55
A Potential New Therapeutic Direction for Fibrosis in the Injured Heart Orchestrated by Cardiac MSCs54
CXC-Chemokine-Receptor-Type-5 Expression on Circulating Naive B Cells Predicts Improvement After Cardiac Resynchronization Therapy54
Full Issue PDF54
Stability of Ready-to-Use Solutions of Acetylcholine for Intracoronary Provocative Testing50
Cold-Inducible RNA-Binding Protein in Cardiac Arrest and Renal Ischemia-Reperfusion Injury44
It’s Time to Put the Term “Pulmonary Vasodilators” to Rest38
Recognizing Early Career Translational Investigators38
Full Issue PDF38
Translational Insights in Coronary Microvascular Disease36
Device-Based Ventricular Reverse Remodeling36
Fueling the Failing Heart35
A (Alpha1-Adrenergic Receptors), B (Blocking Alpha1-Adrenergic Receptors), C (Catecholamines)35
New Insights in the Pathology of Chronic Thromboembolic Pulmonary Hypertension34
FULL ISSUE PDF33
Can Paclitaxel Coated Balloons Have a Deep Impact on Critical Limb Ischemia?33
Remembering Jeff Robbins31
New Insights Into the Role of GSK-3 in the Regulation of Human Cardiac Electrophysiology30
Immune Cells, Superheroes or Villains?29
Tissue Rings PLOD Out a Second Hit in Becker Muscular Dystrophy29
Editorial Board29
Full Issue PDF28
Full Issue PDF28
Editorial Board27
Introducing the 2024 THT Shark Tank Edition of JACC: Basic to Translational Science26
Editorial Board26
Validation of a Novel Renal Denervation System With Cryoablation25
A Subcutaneous Multiparameter Sensor With Integrated Interstitial Fluid Pressure Measurement for Remote Heart Failure Monitoring25
Translating Imaging Into 3D Printed Cardiovascular Phantoms24
Cardiac Transcriptome Remodeling and Impaired Bioenergetics in Single-Ventricle Congenital Heart Disease24
Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF23
Emerging Pathways of Action of Eicosapentaenoic Acid (EPA)23
Semaglutide in Heart Failure With Preserved Ejection Fraction22
Have Your Sodium-Glucose Cotransporter 2 Inhibitor–Derived Ketones and Eat Them Too22
Editorial Board21
Intrinsic and Extrinsic Contributors to the Cardiac Benefits of Exercise21
New Insights Into the Therapy for Lamin-Associated Dilated Cardiomyopathy21
Low-Grade Inflammation21
Mitochondrial DNA in Uremia and New Targets to Treat Myocardial Hypertrophy in the Cardiorenal Syndrome21
Obesity-Induced Coronary Microvascular Disease Is Prevented by iNOS Deletion and Reversed by iNOS Inhibition21
Editorial Board21
JACC: Basic to Translational Science Top Reviewers 2023: With Appreciation and Gratitude21
Is it Time to Abandon the Use of P-Values in Early Phase Translational Trials: Why (Effect) Size Matters21
Reading a Good Transcript Soothes MYZAPed Heart21
Autophagy in the LVAD-Supported Heart20
Clinical Implication of Transvalvular Unloading With Venoarterial Extracorporeal Membrane Oxygenation Support in Acute Myocardial Infarction20
Circadian-Regulated Cardiac Metabolism Involves Transcription Factor E4BP420
Targeting Syntaxin 17 to Improve Mitophagy in Heart Failure20
Is Laser Doppler Perfusion Imaging Truly a “Gold Standard” for Preclinical Peripheral Artery Disease Research?19
Full Issue PDF19
Full Issue PDF19
Clonal Expansion in Cardiovascular Pathology18
Structure-Based Probe Reveals the Presence of Large Transthyretin Aggregates in Plasma of ATTR Amyloidosis Patients18
Dynamic Multiscale Regulation of Perfusion Recovery in Experimental Peripheral Arterial Disease18
Targeting the Gut-Heart Axis Improves Cardiac Remodeling in a Clinical Scale Model of Cardiometabolic Syndrome18
JACC: Basic to Translational Science 2023 Thomas Force Young Investigator Award Winner18
miR-590-3p Overexpression Improves the Efficacy of hiPSC-CMs for Myocardial Repair18
Electroanatomical Navigation to Minimize Contrast Medium or X-Rays During Stenting17
Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome17
Beneficial Effects of Low-Intensity Pulsed Ultrasound Therapy on Right Ventricular Dysfunction in Animal Models17
Low-Grade Inflammation in Long COVID Syndrome Sustains a Persistent Platelet Activation Associated With Lung Impairment17
Genetic Catalytic Inactivation of GRK5 Impairs Cardiac Function in Mice Via Dysregulated P53 Levels17
Injectable Myocardial Matrix Hydrogel Mitigates Negative Left Ventricular Remodeling in a Chronic Myocardial Infarction Model16
Primate Model Carrying LMNA Mutation Develops Dilated Cardiomyopathy16
RBM15 Protects From Myocardial Infarction by Stabilizing NAE116
Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction16
Viewing Pulmonary Arterial Hypertension Pathogenesis and Opportunities for Disease-Modifying Therapy Through the Lens of Biomass16
Myocardial Matrix Hydrogels Mitigate Negative Remodeling and Improve Function in Right Heart Failure Model15
The Imperative to Enhance Cost-Effectiveness for Cardiovascular Therapeutic Development15
Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction15
Murine Ischemia Reperfusion Without Endotracheal Intubation or Ventilation15
Shear-Sensitive circRNA-LONP2 Promotes Endothelial Inflammation and Atherosclerosis by Targeting NRF2/HO1 Signaling15
Percutaneous LAAO and Pulsed-Field Isolation in a Canine Model15
Direct Interstitial Decongestion in an Animal Model of Acute-on-Chronic Ischemic Heart Failure15
Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-1914
Genetic Testing in Familial Hypercholesterolemia14
PD-1 Checkmate and the 2-Edged Sword of the Immune System14
The Quest for an Early Marker of Anthracycline-Induced Cardiotoxicity14
High-Throughput Microscopy Characterization of Rare LDLR Variants14
Pericardial Fluid of Patients With Coronary Artery Disease Can Drive Fibrosis Via TGF-Beta Pathway13
Correction13
Linking Physiology and Biology in Plaque Erosion13
Erythrocytes Induce Vascular Dysfunction in COVID-1913
When Off-Target Is the Target13
Targeting Mitochondria Dysfunction in LMNA Cardiomyopathy13
H2 Inhibits the Formation of Neutrophil Extracellular Traps13
Non-Cell-Autonomous Cardiomyocyte Regulation Complicates Gene Supplementation Therapy for Lmna-Associated Cardiac Defects in Mice12
Endothelial Overexpression of TGF-β-Induced Protein Impairs Venous Thrombus Resolution12
Endothelial Shear Stress Metrics Associate With Proinflammatory Pathways at the Culprit Site of Coronary Erosion12
The Efficacy of Risk Factor Modification Compared to NAD+ Repletion in Diastolic Heart Failure11
1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model11
Association Between Thrombogenicity Indices and Coronary Microvascular Dysfunction in Patients With Acute Myocardial Infarction11
Deubiquitinase USP25 Alleviates Obesity-Induced Cardiac Remodeling and Dysfunction by Downregulating TAK1 and Reducing TAK1-Mediated Inflammation11
Cardiovascular Disease in Duchenne Muscular Dystrophy11
Right Heart Failure in Mice Upon Pressure Overload Is Promoted by Mitochondrial Oxidative Stress11
Preclinical Evaluation of a Novel Cryo Renal Denervation System11
Junctional Ectopic Tachycardia Caused by Junctophilin-2 Expression Silencing Is Selectively Sensitive to Ryanodine Receptor Blockade11
Novel GSK-3β Inhibitor Neopetroside A Protects Against Murine Myocardial Ischemia/Reperfusion Injury10
Cardiac Adrenergic Activation in Heart Failure With Preserved Ejection Fraction10
The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury10
Platelets10
Sex-Dependent Effect of Platelet Nitric Oxide10
Mechanisms of the “No-Reflow” Phenomenon After Acute Myocardial Infarction10
Myopathic Cardiac Genotypes Increase Risk for Myocarditis10
Wharton’s Jelly–Mesenchymal Stem Cell–Engineered Conduit for Pulmonary Artery Reconstruction in Growing Piglets10
Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes9
The Emerging Role of Circular RNAs in Cardio-Oncology9
Full Issue PDF9
Full Issue PDF9
Inflammatory Effects of Triglycerides9
Sailing the Uncharted Waters of Familial Hypercholesterolemia LDL Receptor Genetic-Related Variants9
Safety, Feasibility of Controllable Decrease of Vena Cava Pressure by Doraya Catheter in Heart Failure9
Platelet-Derived Growth Factors9
Instructions for Authors9
Mind the Gap9
Vent to Prevent?8
ApoM Activates Autophagy and Suppresses Lyosomal Lethargy to Combat Doxorubicin Cardiomyopathy8
The Antioxidant Vitamin B12 Analogue Cobinamide as a Treatment for Marfan Syndrome8
Full Issue PDF8
Detecting and Targeting Inflammation in Genetic Cardiomyopathies8
Shark Attack8
Are 3 Aorta Pumps Better Than 1 Transaortic to Preserve Von Willebrand Factor?8
Plasminogen Activator Inhibitor-1–Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype8
Molecular Signature of HFpEF8
Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model7
Oral Nitrate and Platelet Reactivity7
Full Issue PDF7
Reply7
Transcatheter Pulmonary Artery Banding for HFrEF7
JACC Journals’ Pathway Forward With AI Tools7
6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model7
Full Issue PDF7
Heart Failure Solutions7
Editorial Board7
State-of-the-Art Cardiovascular Technology7
Can We Use Viscoelastic Testing to Evaluate Microvascular Dysfunction in Acute Myocardial Infarction?7
Homophilic Interaction Between Transmembrane-JAM-A and Soluble JAM-A Regulates Thrombo-Inflammation7
Spatial Distribution of Calcium Sparks Determines Their Ability to Induce Afterdepolarizations in Human Atrial Myocytes7
Proteomic Analyses Unveil Actionable Disease Pathways in COVID-197
Synergizing Light and Machine Learning to Comprehensively Reveal Coronary Plaque Composition6
Reply6
The Pursuit of a Perfect Conduit6
PCSK9-Inhibition to Quench Vascular Injury in Chronic Limb Threatening Ischemia6
Editorial Board6
In the Ongoing Conflict Between Ideology and Immunity, Which Side Will Protect the Children From Post-Acute Sequelae of COVID-19?6
Red Blood Cell Transfusion and Cardiac Surgery–Associated Acute Kidney Injury6
Is Endogenous Fibrinolysis a Major Player in Occurrence of Atherothrombotic Events Following Acute Myocardial Infarction?6
Will Gene Editing Orphanize Rare Diseases?6
Recognizing Early Career Translational Investigators6
Decreased FAM13B Expression Increases Atrial Fibrillation Susceptibility by Regulating Sodium Current and Calcium Handling6
Pleiotropic Effects of Pyruvate Kinase M2 in Right Ventricular Failure and Pulmonary Arterial Hypertension6
Full Issue PDF6
BNP and Precision Medicine6
Promising But Not Yet the Promised Land6
Editorial Board6
Endothelial JCAD Worsens Acute Ischemic Stroke Outcomes by Enhancing Inflammation in Response to Ischemia/Reperfusion5
Addressing the Reproducibility Crisis in Science5
Editorial Board5
New Drug-Coated Balloons on the Horizon5
Characterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart5
A Novel Device for Tricuspid Regurgitation Reduction Featuring 3-Dimensional Leaflet and Atraumatic Anchor5
Therapeutic Efficacy of a Novel Pharmacologic GRK2 Inhibitor in Multiple Animal Models of Heart Failure5
Editorial Board5
Full Issue PDF5
Articulating the JACC Journals' Direction in Times of Global Change5
TCF7L1 Exacerbates Abdominal Aortic Aneurysm Prevalence and Severity5
Full Issue PDF5
β-Hydroxybutyrate Facilitates Homeostasis of Hypoxic Endothelial Cells After Myocardial Infarction via Histone Lysine β-Hydroxybutyrylation of CPT1A5
Editorial Board5
PCSK9 Inhibition5
Inflammasome Signaling, Thromboinflammation, and Venous Thromboembolism5
Reducing Abdominal Aortic Aneurysm Progression by Blocking Neutrophil Extracellular Traps Depends on Thrombus Formation5
Metabolomic Signatures of Myocardial Glucose Uptake on Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography4
Loss of Cardiac Splicing Regulator RBM20 Is Associated With Early-Onset Atrial Fibrillation4
Targeting Soluble TGF-β Factors4
Integration of Biomarker Polygenic Risk Score Improves Prediction of Coronary Heart Disease4
Noninvasive Stereotactic Radiotherapy for PADN in an Acute Canine Model of Pulmonary Arterial Hypertension4
PECUU-ECM Patches4
The Uses and Misuses of Mendelian Randomization in Clinical and Translational Science4
Deleterious Anti-Inflammatory Macrophage Recruitment in Early Post-Infarction Phase4
Erratum4
Clinical Phenotypes of Heart Failure With Preserved Ejection Fraction to Select Preclinical Animal Models4
Off-Label Use vs Off-Label Marketing of Drugs4
Proteome-Wide Genetic Investigation of Large Artery Stiffness4
TCF7L1 Accelerates Smooth Muscle Cell Phenotypic Switching and Aggravates Abdominal Aortic Aneurysms4
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy4
Apolipoprotein A-I for Cardiac Recovery Post–Myocardial Infarction4
Dysbiosis and Intestinal Barrier Dysfunction in Pediatric Congenital Heart Disease Is Exacerbated Following Cardiopulmonary Bypass4
Proarrhythmic Remodeling of Atrial Myocyte Ca2+ Handling in Atrial Fibrillation4
Can a Biohybrid Patch Salvage Ventricular Function at a Late Time Point in the Post-Infarction Remodeling Process?4
Novel Tryptophan Hydroxylase Inhibitor TPT-001 Reverses PAH, Vascular Remodeling, and Proliferative-Proinflammatory Gene Expression4
Full Issue PDF4
Synchronized Diaphragmatic Stimulation for the Treatment of Symptomatic Heart Failure4
Semaglutide Reduces Cardiomyocyte Size and Cardiac Mass in Lean and Obese Mice4
SIRT1 Ameliorates Lamin A/C Deficiency-Induced Cardiac Dysfunction by Promoting Mitochondrial Bioenergetics4
Do Not Lose Your Nerves4
Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology4
Editorial Board4
CCM Function in the Heart4
Crizanlizumab4
Associations of Epigenetic Age Acceleration With CVD Risks Across the Lifespan4
Rivaroxaban, a Direct Oral Factor Xa Inhibitor, Attenuates Atherosclerosis by Alleviating Factor Xa–PAR2-Mediated Autophagy Suppression4
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