JACC-Basic to Translational Science

Article	Citations
PD-1 Checkmate and the 2-Edged Sword of the Immune System	113
New Insights Into the Role of GSK-3 in the Regulation of Human Cardiac Electrophysiology	95
FULL ISSUE PDF	75
A Potential New Therapeutic Direction for Fibrosis in the Injured Heart Orchestrated by Cardiac MSCs	72
Editorial Board	71
Recognizing Early Career Translational Investigators	70
Electroanatomical Navigation to Minimize Contrast Medium or X-Rays During Stenting	64
Mitochondrial DNA in Uremia and New Targets to Treat Myocardial Hypertrophy in the Cardiorenal Syndrome	55
Is Laser Doppler Perfusion Imaging Truly a “Gold Standard” for Preclinical Peripheral Artery Disease Research?	54
Right Heart Failure in Mice Upon Pressure Overload Is Promoted by Mitochondrial Oxidative Stress	47
Low-Grade Inflammation in Long COVID Syndrome Sustains a Persistent Platelet Activation Associated With Lung Impairment	45
Targeting Syntaxin 17 to Improve Mitophagy in Heart Failure	45
Full Issue PDF	43
Is it Time to Abandon the Use of P-Values in Early Phase Translational Trials: Why (Effect) Size Matters	41
CXC-Chemokine-Receptor-Type-5 Expression on Circulating Naive B Cells Predicts Improvement After Cardiac Resynchronization Therapy	41
Reading a Good Transcript Soothes MYZAPed Heart	39
When Off-Target Is the Target	39
Unveiling the PGAM5-ANGPTL3 Axis	38
H2 Inhibits the Formation of Neutrophil Extracellular Traps	37
Validation of a Novel Renal Denervation System With Cryoablation	37
Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome	37
Reducing Plasma Factor XI Concentration With siRNA Technology	37
JACC: Basic to Translational Science 2016-2025	35
Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model Induced by Bilateral Pulmonary Vein Banding	34
1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model	33

Molecular Signature of HFpEF	32
New Drug-Coated Balloons on the Horizon	31
Full Issue PDF	31
6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model	30
Therapeutic Efficacy of a Novel Pharmacologic GRK2 Inhibitor in Multiple Animal Models of Heart Failure	30
Characterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart	29
Is Endogenous Fibrinolysis a Major Player in Occurrence of Atherothrombotic Events Following Acute Myocardial Infarction?	29
Recognizing Early Career Translational Investigators	29
Can We Use Viscoelastic Testing to Evaluate Microvascular Dysfunction in Acute Myocardial Infarction?	28
Addressing the Reproducibility Crisis in Science	27
Cardiomyocyte Alpha-1A Adrenergic Receptors Mitigate Postinfarct Remodeling and Mortality by Constraining Necroptosis	27
Antibody Matrimony in a Duel of Hearts	27
PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction	27
ApoM Activates Autophagy and Suppresses Lyosomal Lethargy to Combat Doxorubicin Cardiomyopathy	27
TCF7L1 Accelerates Smooth Muscle Cell Phenotypic Switching and Aggravates Abdominal Aortic Aneurysms	27
Interferon Interrupted	26
Inflammasome Signaling, Thromboinflammation, and Venous Thromboembolism	26
Exosome-Mediated Angiogenesis Underlies LVAD-Induced Bleeding in Patients With End-Stage Heart Failure	26
SIRT1 Ameliorates Lamin A/C Deficiency-Induced Cardiac Dysfunction by Promoting Mitochondrial Bioenergetics	26
A Novel LncRNA SNHG3 Promotes Osteoblast Differentiation Through BMP2 Upregulation in Aortic Valve Calcification	26
Reply	25
Red Blood Cell-Mediated Cardioprotection Is Impaired in ST-Segment Elevation Myocardial Infarction Patients With Anemia	24
Soluble Programmed Death-1 Predicts Clinical Outcome After STEMI	24
Editorial Board	24
The Farm to Table HFpEF Kitchen	24
Full Issue Pdf	24
Determinants of Endogenous Fibrinolysis in Whole Blood Under High Shear in Patients With Myocardial Infarction	23
Should All Translational Scientists Be Swifties?	23
From Colon to Aortic Aneurysm: Trek of the Treg	23
Epigenetic Regulation of Heart-ECHS	23
A Differentiated Approach Delivering Targeted Thrombectomy for VTE	23
C-Type Natriuretic Peptide in Essential Hypertension	22
When Facts Become Forbidden	22
Glucagon-Like Peptide-1 Receptor Regulates Thromboxane-Induced Human Platelet Activation	22
Inhibiting Serotonin to Treat Pulmonary Arterial Hypertension	21
Phosphoglycerate Mutase 5 Is Important Mediator for Instigating Arterial Lipid Accumulation and Aggravating Atherosclerosis	21
Pulsatile ECMO	21
Shear-Thinning Hydrogel for Delayed Delivery of a Small Molecule Metalloproteinase Inhibitor Attenuates Myocardial Infarction Remodeling	21
Lower Extremity Lymphatic Flow/Drainage Assessment by Indocyanine Green Fluorescent Lymphography in Heart Failure Patients	20
Regions of Highly Recurrent Electrogram Morphology With Low Cycle Length Reflect Substrate for Atrial Fibrillation	20
Editorial Board	20
Large Animal Models for Transcatheter Heart Valve Prosthesis Development	20
TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis	20
ATP-Citrate Lyase in Heart Failure	19
Endocardial Fibrosis Elastosis	19
Nitric Oxide Releasing Nanomaterials for Cardiovascular Applications	19
Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules	18
Reply	18
Fir(e)ing the Rhythm	18
Noninvasive Cardiovascular Imaging in Preclinical Research	17

Full Issue PDF	17
Full Issue Pdf	17
Proteomics of Large Artery Stiffness	17
Full Issue PDF	17
Full Issue PDF	16
Reduced Proteolytic Cleavage of von Willebrand Factor Leads to Aortic Valve Stenosis and Load-Dependent Ventricular Remodeling	16
JACC: Basic to Translational Science Top Reviewers 2022: With Appreciation and Gratitude	16
A Novel Pathway of Platelet Activation in ACS Mediated by LL-37 Immunoglobulin G Autoantibody Immune Complexes	15
Pulsatile Ventricular Assist Platform	15
Full Issue PDF	15
Small Molecule Activators of Mitochondrial Fusion Prevent Congenital Heart Defects Induced by Maternal Diabetes	15
Full Issue PDF	15
Real-Time Revolution	15
Full Issue Pdf	15
The Virtual Patient Simulator	15
Pleiotropic, Cellular Effects of Rivaroxaban on Autophagy Explain Atheroprotective Effects	15
IL-6 Inhibitors and TNF Inhibitors	14
Cardiac Spinal Afferent Denervation Attenuates Renal Dysfunction in Rats With Cardiorenal Syndrome Type 2	14
Ticagrelor Antibiotic Effect	14
Acute Glycogen Synthase Kinase-3 Inhibition Modulates Human Cardiac Conduction	14
Neuregulin-1β Improves Uremic Cardiomyopathy and Renal Dysfunction in Rats	14
The Impact of Semaglutide on Cardiac Mass and Function Requires Further Investigation	14
The Past, Present, and Promising Future of Direct Cardiac Compression Devices	13
Propionate Alleviates Abdominal Aortic Aneurysm by Modulating Colonic Regulatory T-Cell Expansion and Recirculation	13
Reverse Translation of Pericardial Access	13
Reassessing the Mechanisms of PLN-R14del Cardiomyopathy	13
Full Issue PDF	13
When Sensing Goes Wrong	13
Tissue Engineered Vascular Grafts	13
Editorial Board	13
Editorial Board	13
GLP-1 Receptor Agonists, the Holy Grail Preventing Atrial Fibrillation in Patients With T2D?	12
Introducing the 2024 Transcatheter Cardiovascular Therapeutics (TCT) Shark Tank Presentations	12
Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury	12
Autophagy Signaling and Oxidative Stress in Thoracic Aortic Aneurysms	12
Synbiotics and Gut-Heart Axis in Cardiometabolic Disease	12
Where Comity in Science Goes to Die	12
Experimental Models of Hypertrophic Cardiomyopathy	11
Mesenchymal Stromal Cell Delivery Via Cardiopulmonary Bypass Provides Neuroprotection in a Juvenile Porcine Model	11
Editorial Board	11
A Cardiac Amino-Terminal GRK2 Peptide Inhibits Maladaptive Adipocyte Hypertrophy and Insulin Resistance During Diet-Induced Obesity	11
JACC: Basic to Translational Science 2024 Thomas Force Young Investigator Award Winner	11
Partial Heart Transplant Growth and Hemodynamic Function in Piglets	11
Towards Metabolomic-Based Precision Approaches for Classifying and Treating Heart Failure	10
TIMD4hiMHCⅡhi Macrophages Preserve Heart Function Through Retnla	10
Turn(over) the Page	10
Targeting Myocardial Mitochondria-STING-Polyamine Axis Prevents Cardiac Hypertrophy in Chronic Kidney Disease	10
Charting New Real Estate	10
Quality Over Quantity	10
Structural and Functional Adaptations to Exercise Training	10
Autonomic Modulation of Atrial Fibrillation	9
Paradoxical Effect of Caloric Restriction on Overload-Induced Muscle Growth in Diastolic Heart Failure	9
Remembering Ada L. Steininger	9
Full Issue PDF	9
Shielding the Heart	9
FNDC4 Prevents Aging-Related Cardiac Dysfunction	9
Editorial Board	9
Full Issue PDF	9
BAG3 in the Heart	9
Recurrent Adrenergic Stress Provokes Persistent Myocarditis in PD-1–Deficient Mice	9
Intravascular Lithotripsy on Concentric, Eccentric, and Extrastent Calcium	9
With No Lysine Kinase 1 Promotes Metabolic Derangements and RV Dysfunction in Pulmonary Arterial Hypertension	9
Deficiency of GDF-11 Accelerates TAC-Induced Heart Failure by Impairing Cardiac Angiogenesis	9
Differential BMP Signaling Mediates the Interplay Between Genetics and Leaflet Numbers in Aortic Valve Calcification	9
Inhibition of Factor XI Using RBD4059	9
Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension	9
Full Issue PDF	8
Myocardial Infarction Suppresses Protein Synthesis and Causes Decoupling of Transcription and Translation	8
Editorial Board	8
Continuous Monitoring of Blood Pressure and Vascular Hemodynamic Properties With Miniature Extravascular Hall-Based Magnetic Sensor	8
Myocardial Infarction Platelet Gene Expression Signatures in Women	8
Atrial Metabolic Stress	8
Publisher's Note	8
Full Issue PDF	8
Who Should Be Accountable for Scientific Accountability?	8
Tit for TAK1	8
Negative Impact of TET2 Mutations on Long-Term Survival After Transcatheter Aortic Valve Replacement	8
The Cardiac Circadian Clock	8
Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction	8
A (Alpha1-Adrenergic Receptors), B (Blocking Alpha1-Adrenergic Receptors), C (Catecholamines)	8

Left Atrial Glucose Metabolism Evaluation by 18F-FDG-PET in Persistent Atrial Fibrillation and in Sinus Rhythm	8
In Vivo Efficacy of an Adhesive Bioresorbable Patch to Treat Aortic Dissections	8
Parkin Insufficiency Accentuates High-Fat Diet–Induced Cardiac Remodeling and Contractile Dysfunction Through VDAC1-Mediated Mitochondrial Ca2+ Overload	8
Introducing the 2024 THT Shark Tank Edition of JACC: Basic to Translational Science	7
The Quest for an Early Marker of Anthracycline-Induced Cardiotoxicity	7
Low-Grade Inflammation	7
High Maternal Glycine Levels Increase the Risk of Developing Atrial Septal Defect in the Offspring	7
Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction	7
Platelet-Derived Growth Factors	7
Full Issue PDF	7
Translating Imaging Into 3D Printed Cardiovascular Phantoms	7
Erythrocytes Induce Vascular Dysfunction in COVID-19	7
Platelets	7
Intrinsic and Extrinsic Contributors to the Cardiac Benefits of Exercise	7
New Insights in the Pathology of Chronic Thromboembolic Pulmonary Hypertension	7
New Insights Into the Therapy for Lamin-Associated Dilated Cardiomyopathy	7
The Imperative to Enhance Cost-Effectiveness for Cardiovascular Therapeutic Development	7
Cardiac Adrenergic Activation in Heart Failure With Preserved Ejection Fraction	7
Cardiovascular Disease in Duchenne Muscular Dystrophy	7
JACC Journals’ Pathway Forward With AI Tools	7
Are 3 Aorta Pumps Better Than 1 Transaortic to Preserve Von Willebrand Factor?	6
In the Ongoing Conflict Between Ideology and Immunity, Which Side Will Protect the Children From Post-Acute Sequelae of COVID-19?	6
Proteome-Wide Genetic Investigation of Large Artery Stiffness	6
Editorial Board	6
Full Issue PDF	6
PCSK9 Inhibition	6
Heart Failure Solutions	6
Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes	6
Full Issue PDF	6
Editorial Board	6
Editorial Board	6
Will Gene Editing Orphanize Rare Diseases?	6
Controlled Right Ventricular Pressure Overload Can Rescue Left Ventricular Dysfunction by Promoting Biventricular Adaptive Hypertrophy	5
Editorial Board	5
A New Ex Vivo Model to Study Cardiac Fibrosis in Whole Mouse Hearts	5
Mitochondrial Targeted Therapies to Prevent Maternal Diabetes–Induced Congenital Heart Defects	5
Dysregulation of IL-6/MCP-1/STAT3 Axis	5
Deep Image Segmentation for Cardiomyocyte Proliferation	5
Clinical Phenotypes of Heart Failure With Preserved Ejection Fraction to Select Preclinical Animal Models	5
Deleterious Anti-Inflammatory Macrophage Recruitment in Early Post-Infarction Phase	5
Red Blood Cell Transfusion and Cardiac Surgery–Associated Acute Kidney Injury	5
Homophilic Interaction Between Transmembrane-JAM-A and Soluble JAM-A Regulates Thrombo-Inflammation	5
Clonal Hematopoiesis and Transcatheter Aortic Valve Replacement	5
Vagus Nerve Stimulation for Myocardial Ischemia	5
Tie2-Cre–Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury	5
Caloric Restriction Rejuvenates Skeletal Muscle Growth in Heart Failure With Preserved Ejection Fraction	5
The Thomas Force Young Investigator Award	5
Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy	5
Associations of Epigenetic Age Acceleration With CVD Risks Across the Lifespan	5
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy	5
The Antioxidant Vitamin B12 Analogue Cobinamide as a Treatment for Marfan Syndrome	5
A Novel Device for Tricuspid Regurgitation Reduction Featuring 3-Dimensional Leaflet and Atraumatic Anchor	5
The Pathology of Primary Mitral Regurgitation	5
Natriuretic Peptides and Metabolic Hypertension	5
Maintaining Success for Patients With Dilated Cardiomyopathy and Remission of Heart Failure	5
In Memory of Dr Gary D. Lopaschuk, PhD (1955–2025)	5
INKing the Cardiotoxicity Out of Doxorubicin	5
Transvalvular Unloading Mitigates Ventricular Injury Due to Venoarterial Extracorporeal Membrane Oxygenation in Acute Myocardial Infarction	5
Decreased FAM13B Expression Increases Atrial Fibrillation Susceptibility by Regulating Sodium Current and Calcium Handling	5
The Emerging Role of Circular RNAs in Cardio-Oncology	5