OOIR: Observatory of International Research

Papers

(The median citation count of Current Opinion in Biomedical Engineering is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Toward the use of muscle reinnveration for chronic bidirectional control of prostheses to improve functional outcomes of end users	63
Using biophysical cues and biomaterials to improve genetic models	56
From “high” to “how many”: How quantifying receptor abundance links genotype, environment, and therapeutic response	53
Brainy biomaterials: Latest advances in smart biomaterials to develop the next generation of neural interfaces	53
Smart orthopedic biomaterials and implants	41
Porous microneedles: Transdermal salt bridge for biomedical device engineering	39
AAV-based CRISPR-Cas9 genome editing: Challenges and engineering opportunities	39
Bioresorbable vascular metallic scaffolds: Current status and research trends	37
Outlook in tissue-engineered magnetic systems and biomagnetic control	36
Mining microbial organisms to discover and characterize novel CRISPR-Cas systems	33
Contents	33
Design of biocompatible and self-antibacterial titanium surfaces for biomedical applications	32
Emerging trends of discrete Poly(ethylene glycol) in biomedical applications	31
Contents	30
The prospect of electroceutical intervention and its implementation toward intractable neuromuscular diseases	25
Defining omics-based biomarker signatures of metabolic dysfunction-associated steatotic liver disease (MASLD): In vitro studies	25
Artificial intelligence-powered biomedical imaging: Recent achievements and challenges	24
Beyond the nucleus: Translating engineered protein localization to chromatin modifying enzymes	23
AI models for protein design are driving antibody engineering	23
Biophysical determinants of nuclear shape and mechanics and their implications for genome integrity	22
Aging and the extracellular matrix: A tumor-permissive microenvironment driving cancer progression	21
Immune Cell Responses to Fluid Shear: Overview and Design Considerations for In Vitro Modeling	19
Electrospun biomedical nanofibers and their future as intelligent biomaterials	19
Cellular and molecular aspects of mechanobiology of the extracellular matrix	19
Editorial overview: Scaffold-based and scaffold-free approaches for mechanobiology, in vitro disease modeling and treatment	18

Modular and handheld Raman systems for SERS-based point-of-care diagnostics	18
Contents	17
Contents	17
3M engineering approaches to combat high-shear thrombosis: Integrating modeling, microfluidics, and mechanobiology	17
Size principles governing selective neuromodulation and recruitment order of nerve fibers	17
Intelligent biomaterials for cardiovascular applications	17
Current trends and definitions in high-performance antimicrobial strategies	17
Generalizable and explainable deep learning for medical image computing: An overview	16
Thermogelling materials and their important role in biomedical engineering applications	16
Rigid and soft microelectrodes for electrophysiology measurement	16
Trustworthy AI in medical image analysis: A unified perspective built on robustness and layers of trust	15
Gut-on-chip and liver-on-chip platforms for pathophysiological modeling	15
Editorial overview on Nanobiomaterials advances	15
Imaging the microscale mechanical properties of cancer using optical coherence elastography	14
Contents	14
Bioelectronic therapies for chronic pain	14
Editorial overview: Current perspectives in bioelectronic medicine: Mechanisms, technologies, and clinical frontiers	14
Recent advances in quantifying the mechanobiology of cardiac development via computational modeling	14
A new function for nuclear lamins: Providing surface tension to the nuclear drop	14
Eye tracking in cardiology	14
Recent advancements in in vitro models of traumatic brain injury	13
Nano-biomaterials: Emerging tools in biomedical innovation and therapy	13
Sustainable electrospun materials with enhanced blood compatibility for wound healing applications—A mini review	13
Smart plasmonic hydrogels based on gold and silver nanoparticles for biosensing application	13
Remote magnetic actuation of cell signalling for tissue engineering	13
AI-powered wearable sensors for health monitoring and clinical decision making	13
Surface modified NiTi smart biomaterials: Surface engineering and biological compatibility	12
Leveraging user preference in the design and evaluation of lower-limb exoskeletons and prostheses	12
Neuromodulation for the treatment of sexual dysfunction: An opportunity for the field	12
Beyond static models: Mechanically dynamic matrices reveal new insights into cancer and fibrosis progression	12
Genetically-encoded degraders as versatile modulators of intracellular therapeutic targets	11
Microfluidic platforms for organ-on-a-chip models: Creating dynamic microenvironments for organoid and multi-organ systems	11
Commercial autologous cell therapy: The value of real-time patient and therapy data	11
Advances in electrospinning of aligned nanofiber scaffolds used for wound dressings	10
Transdermal nanomedicine: Emerging horizons, unresolved challenges, and the path forward	10
Editorial Board	9
Editorial Board	9
Advances in strategies for liver regeneration and replacement	9
What lies beyond—Insights into elastic microscaffolds with metamaterial properties for cell studies	9
Nanomechanics at the extracellular matrix-focal adhesion interface	9
Gelatin-based scaffolds: An intuitive support structure for regenerative therapy	9
Contemporary standpoint and future of 3D bioprinting in tissue/organs printing	8
Moving to a new dimension: 3D kidney cultures for kidney regeneration	8
Tissue engineering for cervical function in pregnancy	8
Editorial Board	8
Diversity in a dish: Leveraging organoids to reflect genetic ancestry and sex differences in health and disease	8
Long sequence insertion via CRISPR/Cas gene-editing with transposase, recombinase, and integrase	8
Perspectives on synthetic protein circuits in mammalian cells	8
The unperturbed picture: Label-free real-time optical monitoring of cells and extracellular vesicles for therapy	8
The role of immune cells in therapeutic angiogenesis: Concepts in tissue engineering	8

Antimicrobial polymeric composites for high-touch surfaces in healthcare applications	8
The myokinetic interface: Implanting permanent magnets to restore the sensory-motor control loop in amputees	8
The need for tissue-engineered models to facilitate the study of oligodendrocyte progenitor cells in traumatic brain injury and repair	8
Fueling next-generation genome editing with DNA repair	8
Tissue density in the progression of breast cancer: Bedside to bench and back again	8
Intelligent and smart biomaterials for sustainable 3D printing applications	7
Non-invasive brain imaging to advance the understanding of human balance	7
Editorial Board	7
Contents	7
Finite element modeling of traumatic brain injury: Areas of future interest	7
Engineering Lymphatic Vessels and Lymphoid Microenvironments In Vitro to Investigate Immune Cell Trafficking	7
Contents	7
Microphysiological systems for assessing immunotherapy efficacy: from engineering to clinical prediction	7
Engineering the NET-biomaterial interface to treat disease	7
Editorial overview: Low-cost and portable systems for biomedical imaging and sensing	6
Mechanome-guided strategies in regenerative rehabilitation	6
Future of transdermal nanomedicine	6
Achieving tendon enthesis regeneration across length scales	6
Tuning the matrix: Recent advances in mechanobiology unveiled through polyacrylamide hydrogels	6
Intelligent biomaterials for micro and nanoscale 3D printing	6
Trans-epithelial/endothelial electrical resistance (TEER): Current state of integrated TEER measurements in organ-on-a-chip devices	6
Recent advancements and applications of physics-informed machine learning in biomedical research	6
Current opinion: Underreported cell populations in the aortic valve influence tissue development and homeostasis	6
To cut or not to cut: Next-generation genome editors for precision genome engineering	5
An update on repeated blast traumatic brain injury	5
Wearable sensing for understanding and influencing human movement in ecological contexts	5
Spatiotemporally-patterned biomaterials for organoid culture	5
Intelligent polymeric biomaterials surface driven by plasma processing	5
“Sustainable open-source medical devices manufactured with green biomaterials and accessible resources”	5
Regeneration of interfaces bridging disparate tissues and systems of the human body	5
Mechanobiological modulation of extracellular vesicle function and transport dynamics in cancer progression	5
Rehabilitation of motor and sensory function using spinal cord stimulation: Recent advances	5
Micro-haemodynamics at the maternal–fetal interface: Experimental, theoretical and clinical perspectives	5
Artificial intelligence in neurodegenerative disease diagnosis: Advancing Alzheimer’s and Parkinson’s diseases	5
Anatomics: Co-engineering body and machine in pursuit of synergistic bionic performance	5
Mechanism to translation: Neural prostheses for the lower urinary tract	5
Contents	5
Contents	5
Rewriting the epigenome: CRISPR tools for biological discovery and therapeutics	5
Contents	5
Engineering the organoid niche to build better human models	5
The dynamic tumor extracellular matrix: Biophysical cues, cellular crosstalk, and disease progression	5
Targeting and editing DNA methylation and hydroxymethylation for gene therapy	4
Editorial overview: Biomedical engineering and women's health: Breaking new ground in gender- and sex-specific research	4
Next generation technologies for CRISPR-based epigenome and transcriptional modulation	4
Microfluidic platforms based on SERS imaging and their point-of-care applications	4
Editorial Board	4
Contents	4
Recent mitigation strategies in engineered healthcare materials towards antimicrobial applications	4
Biosensors in biomedical research: Bridging cell and tissue engineering and real-time monitoring	4
Biomedical imaging: Imaging for regenerative medicine and biomanufacturing	4
Engineering cancer's journey: Emerging tools for metastasis modeling	4
Editorial Board	4
Enhancing resilience against adversarial attacks in medical imaging using advanced feature transformation training	4
Clinical translation of epigenome editing technologies	4
Advancements in in vitro models of traumatic brain injury	4
Interface tissues of the mesoderm: Periosteum, ligament, interosseous membrane, & myofascial tissues, an inspiration for next generation medical textiles	4
Recent progress in multifunctional MXene quantum dots for cancer therapy	3
Organoid bioprinting to pattern the matrix microenvironment	3
Cellular mechanoactivation of antigen-presenting cells and T cells for cancer immunotherapy	3
Nanomaterials for controlled drug delivery in wound healing: Recent advances and future directions	3
Application of metal additive manufacturing in oral dentistry	3
Photonic crystal colorimetric sensing in heart-on-a-chip systems	3
Learning about liver regeneration from liver-on-a-chip	3
Generative design of therapeutics that bind and modulate protein states	3
Paradigms for establishing long-term epigenetic states in brain	3
Biomechanics of cardiac development in zebrafish model	3
Single-use biosensors for biomanufacturing: Perspective on the state-of-the-art	3
Mechanosensing pathways in the progression of pulmonary fibrosis	3
Recent advances in hydrogel-based platforms for periodontal tissue regeneration	3
Vascularization of organoid microenvironments: Perfusable networks for organoid growth and maturation	3
Hippocampus-guided engineering of memory prosthesis	3
Exploiting protein domain modularity to enable synthetic control of engineered cells	3
Quantitative 4D imaging of biomechanical regulation of ventricular growth and maturation	3