OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 68. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
RORγt-lineage APCs: The Aire apparent	412
Characterization of the mammalian prodefinitive angio-hematopoietic lineage	392
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection	304
Is one lymphocyte’s brake another lymphocyte’s gas?	285
The HLA advantage: Why COVID-19 benched you but not your co-worker	249
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells	225
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells	210
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation	208
Intratumoral immunotherapy relies on B and T cell collaboration	207
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation	206
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins	194
Operation Nasal Vaccine—Lightning speed to counter COVID-19	190
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression	181
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity	166
CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity	165
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling	160
Clonally expanded CD38 ^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis	157
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses	153
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5	139
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics	127
ILC2s—Bipartisan politicians in cancer	126
Neither naïve nor anergic, “autoimmune” not allergic	126
Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins	125
Antibody-mediated immunity against lung cancer goes retro	125
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity	123

Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models	122
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation	119
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease	117
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens	117
CD103 fate mapping reveals that intestinal CD103⁻tissue-resident memory T cells are the primary responders to secondary infection	113
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity	111
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ	109
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis	109
Epithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation	107
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24	100
Tissue origin and virus specificity shape human CD8 ⁺ T cell cytotoxicity	98
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination	98
Erratum for the Research Article “TGF-β specifies T _FH versus T _H 17 cell fates in murine CD4 ⁺	95
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia	95
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing	94
Maternal allergy and neonatal RSV infection synergize via FcR-mediated allergen uptake to promote the development of asthma in early life	93
RNA exosome drives early B cell development via noncoding RNA processing mechanisms	93
Antigen-specific depletion of CD4 ⁺ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity	92
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis	89
Androgen conspires with the CD8 ⁺ T cell exhaustion program and contributes to sex bias in cancer	89
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge	88
BCL6 is required for the thymic development of TCRαβ ⁺ CD8αα ⁺ intraepithelial lymphocyte lineage	87
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling	85
Dynamic STING repression orchestrates immune cell development and function	83
SLAMF7 engagement superactivates macrophages in acute and chronic inflammation	83
Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance	83
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 ⁺ PD-1 ⁺ CD8 T cells	82
CD39 ⁺ tissue-resident memory CD8 ⁺ T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer	82
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity	81
Immune determinants of chronic sequelae after respiratory viral infection	81
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine	80
CD5 deletion enhances the antitumor activity of adoptive T cell therapies	79
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis	76
Gutsy memory T cells stand their ground against pathogens	74
CAR keys to unlock the intracellular immunopeptidome	72
Neutrophils and macrophages drive TNF-induced lethality via TRIF/CD14-mediated responses	72
Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice	71
Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function	71
Early human lung immune cell development and its role in epithelial cell fate	71
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells	70
An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence	69
Serine enrichment in tumors promotes regulatory T cell accumulation through sphinganine-mediated regulation of c-Fos	69
Tissue-specific nonheritable influences drive endometrial immune system variation	68
Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination	68