OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells	388
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation	380
Is one lymphocyte’s brake another lymphocyte’s gas?	278
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation	275
Operation Nasal Vaccine—Lightning speed to counter COVID-19	263
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation	217
Clonally expanded CD38 ^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis	204
RORγt-lineage APCs: The Aire apparent	202
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses	200
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection	197
The HLA advantage: Why COVID-19 benched you but not your co-worker	195
CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity	195
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling	190
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5	190
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics	183
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity	178
Intratumoral immunotherapy relies on B and T cell collaboration	158
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression	158
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells	156
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins	153
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens	152
CD103 fate mapping reveals that intestinal CD103⁻tissue-resident memory T cells are the primary responders to secondary infection	142
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24	139
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity	139
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ	123

Pulmonary BCG induces lung-resident macrophage activation and confers long-term protection against tuberculosis	123
Antibody-mediated immunity against lung cancer goes retro	121
ILC2s—Bipartisan politicians in cancer	121
Neither naïve nor anergic, “autoimmune” not allergic	119
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation	117
Epithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation	116
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis	115
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity	114
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination	109
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease	107
DuraBle tolerance to CNS antigens	107
Dynamic STING repression orchestrates immune cell development and function	105
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling	105
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia	101
Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance	101
Erratum for the Research Article “TGF-β specifies T _FH versus T _H 17 cell fates in murine CD4 ⁺	93
BCL6 is required for the thymic development of TCRαβ ⁺ CD8αα ⁺ intraepithelial lymphocyte lineage	92
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing	92
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine	88
Androgen conspires with the CD8 ⁺ T cell exhaustion program and contributes to sex bias in cancer	87
RNA exosome drives early B cell development via noncoding RNA processing mechanisms	87
CD5 deletion enhances the antitumor activity of adoptive T cell therapies	86
Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells	85
Immune determinants of chronic sequelae after respiratory viral infection	84
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge	83
Tissue origin and virus specificity shape human CD8 ⁺ T cell cytotoxicity	83
CD39 ⁺ tissue-resident memory CD8 ⁺ T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer	83
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis	81
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity	80
SLAMF7 engagement superactivates macrophages in acute and chronic inflammation	79
Antigen-specific depletion of CD4 ⁺ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity	79
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis	78
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 ⁺ PD-1 ⁺ CD8 T cells	78
Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors	78
NKG2D-mediated detection of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis	76
Functional differences between rodent and human PD-1 linked to evolutionary divergence	75
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells	75
Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination	73
Effective CD4 T cell priming requires repertoire scanning by CD301b ⁺ migratory cDC2 cells upon lymph node entry	72
Gutsy memory T cells stand their ground against pathogens	71
Androgen effects cause sex-biased impairment of CD8 ⁺ T cell antitumor activity	69
IL-17–dependent fibroblastic reticular cell training boosts tissue protective mucosal immunity through IL-10–producing B cells	69
CAR keys to unlock the intracellular immunopeptidome	67
IgE plasma cells are transcriptionally and functionally distinct from other isotypes	67
Unearthing the Rosetta Stone of public antibody responses	67