OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 68. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5	334
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling	310
Hypoxia-induced EGR1 remodels neutrophils to suppress antitumor immunity	273
Characterization of the mammalian prodefinitive angio-hematopoietic lineage	269
The HLA advantage: Why COVID-19 benched you but not your co-worker	237
Is one lymphocyte’s brake another lymphocyte’s gas?	200
The OAS–RNase L pathway: Insights from experiments of nature	195
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells	190
Intratumoral immunotherapy relies on B and T cell collaboration	188
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics	151
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation	150
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity	148
Clonally expanded CD38 ^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis	146
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells	144
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression	143
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation	135
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins	135
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses	133
Structural variation tunes apoptotic responses to drive immune escape in melanoma	129
DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and function	125
Operation Nasal Vaccine—Lightning speed to counter COVID-19	119
CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity	113
RORγt-lineage APCs: The Aire apparent	113
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection	112
Neither naïve nor anergic, “autoimmune” not allergic	110

Antibody-mediated immunity against lung cancer goes retro	109
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ	105
Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins	103
CD103 fate mapping reveals that intestinal CD103⁻tissue-resident memory T cells are the primary responders to secondary infection	102
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis	102
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens	100
The rise of spatial TCR profiling: Emerging technologies and open challenges	99
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity	96
ILC2s—Bipartisan politicians in cancer	96
Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models	93
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity	92
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation	89
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination	89
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia	87
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease	87
Dynamic STING repression orchestrates immune cell development and function	86
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis	84
BCL6 is required for the thymic development of TCRαβ ⁺ CD8αα ⁺ intraepithelial lymphocyte lineage	83
Erratum for the Research Article “TGF-β specifies T _FH versus T _H 17 cell fates in murine CD4	83
RNA exosome drives early B cell development via noncoding RNA processing mechanisms	82
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing	82
Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance	82
Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen	78
Immune determinants of chronic sequelae after respiratory viral infection	78
CD5 deletion enhances the antitumor activity of adoptive T cell therapies	77
Antigen-specific depletion of CD4 ⁺ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity	77
CD39 ⁺ tissue-resident memory CD8 ⁺ T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer	77
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling	77
Maternal allergy and neonatal RSV infection synergize via FcR-mediated allergen uptake to promote the development of asthma in early life	76
Tissue origin and virus specificity shape human CD8 ⁺ T cell cytotoxicity	76
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis	74
Androgen conspires with the CD8 ⁺ T cell exhaustion program and contributes to sex bias in cancer	74
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 ⁺ PD-1 ⁺ CD8 T cells	74
Gutsy memory T cells stand their ground against pathogens	73
Serine enrichment in tumors promotes regulatory T cell accumulation through sphinganine-mediated regulation of c-Fos	71
Androgen effects cause sex-biased impairment of CD8 ⁺ T cell antitumor activity	71
Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors	71
Unearthing the Rosetta Stone of public antibody responses	71
Functional differences between rodent and human PD-1 linked to evolutionary divergence	70
Group 2 innate lymphoid cells regulate nociceptive and gait functions of the peripheral nervous system	69
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells	69
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis	69
Intratumoral T _reg cell ablation elicits NK cell–mediated control of CD8 T cell–resistant tumors	69
IgE plasma cells are transcriptionally and functionally distinct from other isotypes	68
Early human lung immune cell development and its role in epithelial cell fate	68