OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation	406
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics	392
Operation Nasal Vaccine—Lightning speed to counter COVID-19	297
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins	282
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling	240
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection	217
Is one lymphocyte’s brake another lymphocyte’s gas?	205
CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity	203
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity	202
RORγt-lineage APCs: The Aire apparent	202
The HLA advantage: Why COVID-19 benched you but not your co-worker	202
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells	193
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses	188
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation	175
Clonally expanded CD38 ^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis	162
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression	161
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5	155
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells	153
Intratumoral immunotherapy relies on B and T cell collaboration	149
Neither naïve nor anergic, “autoimmune” not allergic	148
ILC2s—Bipartisan politicians in cancer	132
Antibody-mediated immunity against lung cancer goes retro	126
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation	125
Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins	124
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24	124

Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models	123
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease	122
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity	121
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis	115
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens	112
CD103 fate mapping reveals that intestinal CD103⁻tissue-resident memory T cells are the primary responders to secondary infection	108
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ	107
Epithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation	107
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity	107
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination	107
DuraBle tolerance to CNS antigens	104
Tissue origin and virus specificity shape human CD8 ⁺ T cell cytotoxicity	98
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia	96
Erratum for the Research Article “TGF-β specifies T _FH versus T _H 17 cell fates in murine CD4 ⁺	95
RNA exosome drives early B cell development via noncoding RNA processing mechanisms	94
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing	94
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis	93
BCL6 is required for the thymic development of TCRαβ ⁺ CD8αα ⁺ intraepithelial lymphocyte lineage	93
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling	91
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 ⁺ PD-1 ⁺ CD8 T cells	89
Immune determinants of chronic sequelae after respiratory viral infection	88
Antigen-specific depletion of CD4 ⁺ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity	87
CD39 ⁺ tissue-resident memory CD8 ⁺ T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer	86
Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells	85
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge	84
Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance	83
Dynamic STING repression orchestrates immune cell development and function	82
Androgen conspires with the CD8 ⁺ T cell exhaustion program and contributes to sex bias in cancer	81
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine	81
CD5 deletion enhances the antitumor activity of adoptive T cell therapies	81
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity	80
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis	79
SLAMF7 engagement superactivates macrophages in acute and chronic inflammation	76
Microbial uptake in oral mucosa–draining lymph nodes leads to rapid release of cytotoxic CD8 ⁺ T cells lacking a gut-homing phenotype	75
Gutsy memory T cells stand their ground against pathogens	74
CAR keys to unlock the intracellular immunopeptidome	73
Androgen effects cause sex-biased impairment of CD8 ⁺ T cell antitumor activity	73
Tissue-specific nonheritable influences drive endometrial immune system variation	73
Unearthing the Rosetta Stone of public antibody responses	70
Antigen cross-presentation in young tumor-bearing hosts promotes CD8 ⁺ T cell terminal differentiation	68
Early human lung immune cell development and its role in epithelial cell fate	68
Group 2 innate lymphoid cells regulate nociceptive and gait functions of the peripheral nervous system	67
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis	67