Science Immunology

Papers
(The H4-Index of Science Immunology is 69. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)
ArticleCitations
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics393
Operation Nasal Vaccine—Lightning speed to counter COVID-19391
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation289
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells281
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection276
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses232
Is one lymphocyte’s brake another lymphocyte’s gas?213
CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity209
The HLA advantage: Why COVID-19 benched you but not your co-worker202
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells200
RORγt-lineage APCs: The Aire apparent199
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression196
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins193
Clonally expanded CD38 hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis191
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling183
Intratumoral immunotherapy relies on B and T cell collaboration168
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation159
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation159
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5158
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity153
Neither naïve nor anergic, “autoimmune” not allergic148
ILC2s—Bipartisan politicians in cancer147
Antibody-mediated immunity against lung cancer goes retro144
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation128
Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins126
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis124
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination123
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity122
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ121
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24120
Epithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation119
CD103 fate mapping reveals that intestinal CD103tissue-resident memory T cells are the primary responders to secondary infection118
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity113
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease110
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens107
DuraBle tolerance to CNS antigens106
Dynamic STING repression orchestrates immune cell development and function106
Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance106
Tissue origin and virus specificity shape human CD8 + T cell cytotoxicity102
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing99
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia95
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge95
Erratum for the Research Article “TGF-β specifies T FH versus T H 17 cell fates in murine CD4 + 95
Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells94
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling92
Androgen conspires with the CD8 + T cell exhaustion program and contributes to sex bias in cancer91
CD39 + tissue-resident memory CD8 + T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer91
RNA exosome drives early B cell development via noncoding RNA processing mechanisms90
Immune determinants of chronic sequelae after respiratory viral infection90
Antigen-specific depletion of CD4 + T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity86
CD5 deletion enhances the antitumor activity of adoptive T cell therapies85
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity84
BCL6 is required for the thymic development of TCRαβ + CD8αα + intraepithelial lymphocyte lineage84
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis84
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine83
SLAMF7 engagement superactivates macrophages in acute and chronic inflammation81
Neutrophils and macrophages drive TNF-induced lethality via TRIF/CD14-mediated responses80
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 + PD-1 + CD8 T cells80
Microbial uptake in oral mucosa–draining lymph nodes leads to rapid release of cytotoxic CD8 + T cells lacking a gut-homing phenotype80
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis80
Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors79
Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion78
Serine enrichment in tumors promotes regulatory T cell accumulation through sphinganine-mediated regulation of c-Fos76
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis73
Gutsy memory T cells stand their ground against pathogens72
CAR keys to unlock the intracellular immunopeptidome70
IL-17–dependent fibroblastic reticular cell training boosts tissue protective mucosal immunity through IL-10–producing B cells70
Early cross-coronavirus reactive signatures of humoral immunity against COVID-1969
Immune signatures underlying post-acute COVID-19 lung sequelae69
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