OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 80. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndrome	771
TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes	770
The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients	724
Comprehensive mapping of immune perturbations associated with severe COVID-19	642
Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19	642
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients	620
Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination	515
Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients	503
SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients	449
Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome	389
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths	337
Natural killer cell immunotypes related to COVID-19 disease severity	324
Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients	322
Inhibition of Bruton tyrosine kinase in patients with severe COVID-19	285
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19	253
Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence	236
Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients	224
SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection	223
Vaccination before or after SARS-CoV-2 infection leads to robust humoral response and antibodies that effectively neutralize variants	220
Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19	184
SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8 ⁺ T cell activation in COVID-19 patients	179
Severely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8 ⁺ T cells	175
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles	170
Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination	170
BNT162b2 vaccination induces durable SARS-CoV-2–specific T cells with a stem cell memory phenotype	165

Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19	158
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection	158
Prolonged evolution of the human B cell response to SARS-CoV-2 infection	152
Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics	146
Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis	145
SARS-CoV-2 infection generates tissue-localized immunological memory in humans	144
Omicron BA.1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes	143
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection	140
Human inborn errors of immunity: An expanding universe	136
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation	136
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8 ⁺ T cell responses	135
Gut microbiota–specific IgA ⁺ B cells traffic to the CNS in active multiple sclerosis	133
MAIT cell activation and dynamics associated with COVID-19 disease severity	131
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses	131
Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19	131
Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2	131
A reservoir of stem-like CD8 ⁺ T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response	128
Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forward	126
TOX is expressed by exhausted and polyfunctional human effector memory CD8 ⁺ T cells	125
Pharmacological activation of STING blocks SARS-CoV-2 infection	125
Clonal expansion and activation of tissue-resident memory-like T _H 17 cells expressing GM-CSF in the lungs of patients with severe COVID-19	124
Early precursors and molecular determinants of tissue-resident memory CD8 ⁺ T lymphocytes revealed by single-cell RNA sequencing	121
The known unknowns of T cell immunity to COVID-19	120
CD8 ⁺ T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19	116
Tissue-resident CD4 ⁺ T helper cells assist the development of protective respiratory B and CD8 ⁺ T cell memory responses	114
SARS-CoV-2 seroprevalence among parturient women in Philadelphia	110
Integrated longitudinal immunophenotypic, transcriptional, and repertoire analyses delineate immune responses in patients with COVID-19	108
Bispecific antibodies targeting mutant RAS neoantigens	106
A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity	105
Polyclonal expansion of TCR Vβ 21.3 ⁺ CD4 ⁺ and CD8 ⁺ T cells is a hallmark of multisystem infl	104
Innate immunological pathways in COVID-19 pathogenesis	104
Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma	102
NLRP3 inflammasome activation triggers gasdermin D–independent inflammation	101
Immune signatures underlying post-acute COVID-19 lung sequelae	101
Human dendritic cells in cancer	100
Multiplexed imaging mass cytometry of the chemokine milieus in melanoma characterizes features of the response to immunotherapy	99
Regulatory T cells in skin injury: At the crossroads of tolerance and tissue repair	98
A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection	98
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination	93
3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope–specific plasma cells and humoral immunity in nonhuman primates	89
Tumor-draining lymph nodes: At the crossroads of metastasis and immunity	89
T cell factor 1: A master regulator of the T cell response in disease	88
IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer	87
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection	87
T cell engagement of cross-presenting microglia protects the brain from a nasal virus infection	87
Understanding T cell responses to COVID-19 is essential for informing public health strategies	86
Microglial autophagy–associated phagocytosis is essential for recovery from neuroinflammation	86
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine	86
Organ-specific isoform selection of fatty acid–binding proteins in tissue-resident lymphocytes	86
Contribution of resident and circulating precursors to tumor-infiltrating CD8 ⁺ T cell populations in lung cancer	85

T resident helper cells promote humoral responses in the lung	83
HiJAKing SARS-CoV-2? The potential role of JAK inhibitors in the management of COVID-19	83
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation	82
COVID-19 vaccine side effects: The positives about feeling bad	81
The expansion of human T-bet ^high CD21 ^low B cells is T cell dependent	81