OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 69. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection	472
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression	387
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells	375
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation	343
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells	278
The HLA advantage: Why COVID-19 benched you but not your co-worker	272
RORγt-lineage APCs: The Aire apparent	253
Operation Nasal Vaccine—Lightning speed to counter COVID-19	206
CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity	199
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins	198
Is one lymphocyte’s brake another lymphocyte’s gas?	193
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation	192
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses	191
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation	190
Intratumoral immunotherapy relies on B and T cell collaboration	190
Clonally expanded CD38 ^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis	185
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics	175
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity	174
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling	157
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5	154
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity	151
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation	151
Neither naïve nor anergic, “autoimmune” not allergic	149
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens	149
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity	136

Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease	136
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24	135
CD103 fate mapping reveals that intestinal CD103⁻tissue-resident memory T cells are the primary responders to secondary infection	121
ILC2s—Bipartisan politicians in cancer	121
Antibody-mediated immunity against lung cancer goes retro	120
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis	118
Epithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation	115
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ	113
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination	113
Pulmonary BCG induces lung-resident macrophage activation and confers long-term protection against tuberculosis	112
DuraBle tolerance to CNS antigens	109
Immune determinants of chronic sequelae after respiratory viral infection	107
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling	106
Dynamic STING repression orchestrates immune cell development and function	104
Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance	102
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge	102
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine	100
Antigen-specific depletion of CD4 ⁺ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity	99
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia	90
Erratum for the Research Article “TGF-β specifies T _FH versus T _H 17 cell fates in murine CD4 ⁺	88
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing	86
Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells	86
RNA exosome drives early B cell development via noncoding RNA processing mechanisms	85
CD39 ⁺ tissue-resident memory CD8 ⁺ T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer	84
Androgen conspires with the CD8 ⁺ T cell exhaustion program and contributes to sex bias in cancer	83
Single-cell analysis pinpoints distinct populations of cytotoxic CD4 ⁺ T cells and an IL-10 ⁺ CD109 ⁺	83
CD5 deletion enhances the antitumor activity of adoptive T cell therapies	82
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis	81
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis	80
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 ⁺ PD-1 ⁺ CD8 T cells	79
SLAMF7 engagement superactivates macrophages in acute and chronic inflammation	79
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity	78
Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors	78
BCL6 is required for the thymic development of TCRαβ ⁺ CD8αα ⁺ intraepithelial lymphocyte lineage	78
Tissue-specific nonheritable influences drive endometrial immune system variation	76
CAR keys to unlock the intracellular immunopeptidome	76
Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function	76
Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion	75
An aging bone marrow exacerbates lung fibrosis by fueling profibrotic macrophage persistence	74
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis	73
Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice	72
Serine enrichment in tumors promotes regulatory T cell accumulation through sphinganine-mediated regulation of c-Fos	72
Unearthing the Rosetta Stone of public antibody responses	71
Antigen cross-presentation in young tumor-bearing hosts promotes CD8 ⁺ T cell terminal differentiation	70