Birth Defects Research

Article	Citations
Believing in science	58
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Developmental exposure to the flame retardant, triphenyl phosphate, causes long‐lasting neurobehavioral and neurochemical dysfunction	25
Society for birth defects research and prevention's multidisciplinary research needs workshop 2022: A call to action	24
Dolutegravir and rat whole embryo culture	22
Periconceptional nonsteroidal anti‐inflammatory drug use, folic acid intake, and the risk of spina bifida	22
Maternal cigarette smoking and alcohol consumption and congenital diaphragmatic hernia	21
Protective Role of Vitamin B6 Against Teratogenic Effects Induced by Lead in Chick Embryo	21
Prenatal Exposure to Methamphetamine and Its Association With Birth Outcomes: A Meta‐Analysis	21
Community‐Engaged Research and the Use of Open Access ToxVal/ToxRef In Vivo Databases and New Approach Methodologies (NAM) to Address Human Health Risks From Environme	20
How Does Maternal Lipopolysaccharide Exposure Impact Prenatal Testicular Development in Rats, and Could α‐Tocopherol Provide a Protective Effect? A Histological, Immunohistochemical and Biochemical St	19
Domestic Use of Solvents and Pesticides and the Risk of Hypospadias in Offspring: A Case–Control Study From Brittany, France	17
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Evaluating the proportion of isolated cases among a spectrum of birth defects in a population‐based registry	16
Application of zebrafish in the study of craniomaxillofacial developmental anomalies	15
Developmental safety of nirmatrelvir in zebrafish (Danio rerio) embryos	14
Cannabidiol impairs neural tube closure in mouse whole embryo culture	14
Using a health observance event to raise awareness: An assessment of World Birth Defects Day	13
Emerging understanding of the effects of cannabis use during pregnancy	13
Developmental toxicity induced by brodifacoum in zebrafish (Danio rerio) early life stages	12
Otocephaly Diagnosed Prenatally: A Case Study of a Rare Congenital Defect	12
Absence of developmental and reproductive toxicity in rats, rabbits, and zebrafish embryos exposed to antimalarial drug cabamiquine	12
In vitro fertilization and pregnancy outcomes of women with X chromosome abnormality: A case series	12
Potential risk factors for hypospadias and negative correlation with DICER1 (rs3742330) A>G variant in Algerian population: A case‐control study	12
A narrative review of exercise dose during pregnancy	12

Antifungal medication use during early pregnancy and the risk of congenital heart defects in the National Birth Defects Prevention Study, 1997–2011	12
Reversible effects on female rat fertility with abrocitinib, a Janus kinase 1 inhibitor	12
Transmission of behavioral and cognitive impairments across generations in rats subjected to prenatal valproic acid exposure	11
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Why Has Gastroschisis Increased Over Time and Why Is It More Common in Infants of Young Mothers?	11
A comparison of infants' birth defects self‐reported by mothers with data provided by general practitioners: Data from the Dutch Pregnancy Drug Register	10
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Prenatal diagnosis of SLC25A24 Fontaine progeroid syndrome: description of the fetal phenotype, genotype and detection of parental mosaicism	10
A case of Williams syndrome with Wolff–Parkinson–White syndrome	10
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Identifying possible inaccuracy in reported birth head circumference measurements among infants in the US Zika Pregnancy and Infant Registry	10
Outcome of children with multicystic dysplastic kidney: Does involved side matter?	10
Malarial PI4K inhibitor induced diaphragmatic hernias in rat: Potential link with mammalian kinase inhibition	10
Issue Information	10
Assessing Environmental Risks Factors in Anorectal Malformations: Case Report and Literature Review	9
Valproic acid induced selective apoptosis of ocular fibrous tunic in mice fetuses	9
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A new 90‐day drinking water study of sodium cyanide in rats to further evaluate National Toxicology Program findings and inform risk assessment	9
Prevalence of critical congenital heart defects and selected co‐occurring congenital anomalies, 2014–2018: A U.S. population‐based study	9
Assessing the Readability, Credibility, and Accuracy of Online Vaccine Information for Pregnant and Lactating Individuals: A Cross‐Platform Analysis	9
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Ezh2‐dependent methylation in oral epithelia promotes secondary palatogenesis	8
Juvenile toxicity study of PF‐07256472/recifercept, a recombinant human soluble fibroblast growth factor receptor 3, in 2–3‐month‐old cynomolgus monkeys	8
Prevalence of congenital anomalies in the Dutch Caribbean islands of Aruba, Bonaire, and Curaçao	8
Birth outcomes following in utero co‐exposure to tobacco and marijuana	8
Determination and analysis of sex ratios in heme oxygenase 1 gene targeted mouse embryos	8
MTHFR promoter methylation might mitigate the effect of smoking at the level of LINE‐1 in cleft lip tissues: A preliminary study	8
Publicly funded healthcare costs associated with orofacial clefts for children born in Alberta, Canada between 2002 and 2018	8
Use of vasoactive medications in pregnancy and the risk of stillbirth among birth defect cases	8
Translational potential of hiPSCs in predictive modeling of heart development and disease	8
An assessment of the reliability of 52 enhanced preliminary embryofetal development studies to detect developmental toxicity	8
Embryo‐fetal safety evaluation of ondansetron in rats	8
MotherToBaby and CDC: Partnering to Provide a Rapid and Personalized Response to COVID‐19 Vaccine Inquiries During Pregnancy and Lactation	8
Post‐mortem rapid aneuploidy testing for holoprosencephaly	7
World health assembly resolution for preventing micronutrient deficiencies and associated neural tube defects—A case study of global partnerships for a successful resolution adoption	7
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Chloroacetonitrile reduces rat prenatal bone length and induces oxidative stress, apoptosis, and DNA damage in rat fetal liver	7
Correction to “Comments on “Maternal–fetal safety evaluation of an aqueous extract of Casearia sylvestris [AECS] leaves in rats” (Nagaoka et al., 2023 [DOI: 10.1002/bdr2.2	7
The accuracy of hospital discharge data in recording major congenital anomalies in Australia	7
Enhancing the Classification of Congenital Heart Defects for Outcome Association Studies in Birth Defects Registries	7
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Intake of Trans‐Fat Diet With Prenatal Bisphenol A Exposure Induce Global DNA Methylation in Rats Offspring	7
Racial and ethnic differences in infant survival for hydrocephaly—Texas, 1999–2017	7
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Correction to “Determination and analysis of sex ratios in heme oxygenase 1 gene targeted mouse embryos”	7
Rodent anogenital distance recommendations	6
Survival of Children With Critical Congenital Heart Defects in the National Birth Defects Prevention Study	6
Sex‐dependent alterations of inflammatory factors, oxidative stress, and histopathology of the brain‐gut axis in a VPA‐induced autistic‐like model of rats	6
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2020: 30‐Year anniversary of gaining knowledge about folic acid's prevention potential for ne	6

Protective effect of Agaricus bisporus mushroom against maternal and fetal damage induced by lead administration during pregnancy in rats	6
Hypothesized pathogenesis of acardius acephalus, acormus, amorphus, anceps, acardiac edema, single umbilical artery, and pump twin risk prediction	6
Birth defects surveillance: Working together to advance science	6
The outcome and complications of modern staged repair surgery in newborns with classic bladder exstrophy in different genders: A retrospective study	6
Associations between maternal reports of periconceptional fever from miscellaneous causes and structural birth defects	6
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Paternal Valproate Treatment and Risk of Childhood Neurodevelopmental Disorders: Precautionary Regulatory Measures Are Insufficiently Substantiated	6
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2022	6
Knowledge of periconceptional folic acid supplementation and associated factors among pregnant women attending antenatal care at public health facilities in Hawassa, South Ethiopia	6
Periconceptional use of vitamin A and the risk of giving birth to a child with nonsyndromic orofacial clefts—A meta‐analysis	6
Ascertainment of malformations in pregnancy registries: Lessons learned in the North American AED Pregnancy Registry	6
A Generalized Machine Learning Model for Identifying Congenital Heart Defects (CHDs) Using ICD Codes	5
Homozygous LOXL2 variant in individuals affected by non‐syndromic occipital encephalocele	5
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Recommendation to change the peer review process	5
Gestational exposure to continuous light impairs the development of the female reproductive system in adult Wistar rat offspring	5
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Maternal Separation Exhibits a Sex Dimorphism in Memory Impairments in Adolescent Rats: Acute Methylphenidate Administration as a Treatment	5
Prenatal alcohol exposure can be determined from baby teeth: Proof of concept	5
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Risk of birth defects by pregestational type 1 or type 2 diabetes: National Birth Defects Prevention Study, 1997–2011	5
Multiple subtypes of coxsackievirus group B can cause congenital heart disease	5
Comparative anatomy, pre‐ and postnatal changes during the development and maturation of the small intestine: Life‐stage influences on exposure	5
Maternal Exposure to Tap Water Disinfection By‐Products and Risk of Selected Congenital Heart Defects	5
Sodium valproate exposure influences the expression of pparg in the zebrafish model	5
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Reproductive and neurobehavioral effects of maternal exposure to dinotefuran in the F1‐generation mice	5
Revisiting the testicular toxicity of cyanide: Assessment of the new and existing literature	5
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Maternal exposure to heparin products and risk of birth defects in the National Birth Defects Prevention Study	5
Population‐based surveillance for birth defects potentially related to Zika virus infection including 3‐year mortality and developmental outcomes, and Early Intervention Program service use—New York C	5
Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring	5
Assessment of postnatal femur development in Wistar Han rats	5
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Life Course Considerations in Environmental Health: Developmental Neurotoxicity of Domoic Acid at Doses Below Acute Effect Levels in Adult Humans	5
Protective effect of quercetin on fetal development and congenital skeletal anomalies against exposure of pregnant Wistar rats to crude oil vapor	4
Maternal diabetes as a teratogenic factor for congenital heart defects in infants of diabetic mothers	4
The association of nausea and vomiting of pregnancy, its treatments, and select birth defects: Findings from the National Birth Defect Prevention Study	4
Epigenetic regulation of craniofacial development and disease	4
Review of the state of science and evaluation of currently available in silico prediction models for reproductive and developmental toxicity: A case study on pesticides	4
Early pregnancy vitamin D status and risk of select congenital anomalies in the National Birth Defects Prevention Study	4
Temporal Trends of Infant Mortality Secondary to Congenital Heart Disease: National CDC Cohort Analysis (1999–2020)	4
Mycophenolate mofetil exposure on embryonic and fetal ear development in rats during pregnancy	4
A case‐control study characterizing polydactyly risk factors in Bogotá and Cali, Colombia between 2002 and 2020	4
In‐utero cannabis exposure and long‐term psychiatric and neurodevelopmental outcomes: The limitations of existing literature and recommendations for future research	4
Analysis of incidence data in developmental toxicity studies: Statistical tests to account for litter effects in fetal defect data	4
Pregnancy and infant outcomes by trimester of SARS‐CoV‐2 infection in pregnancy–SET‐NET, 22 jurisdictions, January 25, 2020–December 31, 2020	4
Issue Information	4
A multi‐program analysis of cleft lip with cleft palate prevalence and mortality using data from 22 International Clearinghouse for Birth Defects Surveillance and Research programs, 1974–2014	4
A Supra‐Numerary Limb Grafted Onto a Sacrococcygeal Mass in a Child With Spinal Dysraphism: Case Report, Dysmorphogenesis, and Management Review	4
Beyond Aggregate Risk: Drug‐ and Organ‐Specific Nuances in Counseling on Antidepressant Teratogenicity	4
Association Between Self‐Reported Infections and Seropositivity Among Pregnant Women With Gastroschisis: A Case Control Study, With Emphasis on Chlamydia trachomatis	4
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Hypothesis: By‐products of vascular disruption carried in the CSF affect prenatal brain development	4
Factors associated with Medicaid participation among infants born with birth defects in Texas, 2010–2014	4
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Blastocyst Cavity Expansion Promotes Cell Polarization During Early Development of Mouse Embryos	4
Comparing Folic Acid Interventions and Arsenic Reduction Strategies for Neural Tube Defect Prevention in Bangladesh: A Systematic Review and Decision Analysis	4
Subdivided Historical Data to Assess Replicability of the Rat Embryo‐Fetal Developmental Toxicity Study	3
A putative adverse outcome network for neonatal mortality and lower birth weight in rodents: Applicability to per‐ and polyfluoroalkyl substances and relevance to human health	3
Conjoined twins and conjoined triplets: At the heart of the matter	3
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Gastroschisis prevalence patterns in 27 surveillance programs from 24 countries, International Clearinghouse for Birth Defects Surveillance and Research, 1980–2017	3
Factors associated with infant sex and preterm birth status for selected birth defects from the National Birth Defects Prevention Study, 1997–2011	3
Prevalence of neural tube defects, maternal HIV status, and antiretroviral therapy from a hospital‐based birth defect surveillance in Kampala, Uganda	3
Describing characteristics of adults with and without congenital heart defects hospitalized with COVID‐19	3
Early childhood outcomes of NICU graduates with cytomegalovirus infection in California	3
Observed Prevalence of Congenital Situs Inversus in the United States Before and During the SARS‐CoV‐2 Pandemic, 2017–2022	3
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Climate and environmental changes exacerbate health disparities in pregnant people and their offspring. How can we protect women and their babies?	3
Prophylactic use of cardiac medications for delay of left ventricular dysfunction in Duchenne muscular dystrophy	3
Gestational exposure to triphenyl phosphate induces epigenetic modifications in C57Bl/6 fetal liver	3
Additional evidence for the vascular disruption defect hypothesis in a novel case of brainstem disconnection syndrome	3
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Investigating the association between vitamin D dietary intake during pregnancy and incidence of clubfoot in neonates	3

Natural history study of Pseudoachondroplasia: A focus on oral health	3
The timing, duration, and severity of nausea and vomiting of pregnancy and adverse birth outcomes among controls without birth defects in the National Birth Defects Prevention Study	3
Regulation of Oct4 in stem cells and neural crest cells	3
Daphne Trasler: In memoriam	3
High glucose impairs osteogenic differentiation of embryonic stem cells via early diversion of beta‐catenin from Forkhead box O to T cell factor interaction	3
Is gastroschisis associated with county‐level socio‐environmental quality during pregnancy?	3
Maternal Age‐Related Gender Bias in Trisomy 21 and Trisomy 18	3
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Hdac1 and Hdac2 positively regulate Notch1 gain‐of‐function pathogenic signaling in committed osteoblasts of male mice	3
Neighborhood social deprivation and healthcare utilization, disability, and comorbidities among young adults with congenital heart defects: Congenital heart survey to recognize outcomes, needs, and we	3
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Measurement of Androgen‐Sensitive Preweaning Developmental Landmarks in Rodents: Best Practices and Toxicological Significance	3
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Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues	3
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries	3
Alobar holoprosencephaly in mining‐related areas of the Eastern region of the Democratic Republic of the Congo: A case series	3
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Vitelline vascular remnant causing intestinal obstruction in a patient with TARP syndrome	3
The prenatal use of agmatine prevents social behavior deficits in VPA‐exposed mice by activating the ERK/CREB/BDNF signaling pathway	3
COVID‐19 Vaccination During Pregnancy and Birth Defects: Results From the CDC COVID‐19 Vaccine Pregnancy Registry, United States 2021–2022	2
Survival of infants and children born with severe microcephaly, Texas, 1999–2015	2
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High glucose‐increased miR‐200c contributes to cellular senescence and DNA damage in neural stem cells	2
Maternal immunization with Group B Streptococcus six‐valent polysaccharide conjugate vaccine supported by lack of toxicity in rat and rabbit fertility and developmental toxicity stud	2
Parietal bone agenesis and athelia in retinoic acid embryopathy: An expansion of the phenotype	2
New classification of the penoscrotal positional anomalies	2
The relationship between maternal periconceptional micronutrient supplementation and non‐syndromic cleft lip/palate in offspring	2
Real‐world prevalence, time of diagnosis, and co‐occurrence patterns of birth defects in live‐born infants, 2014–2020: A health administrative database study in Japan	2
Genitourinary infection and gastroschisis: A systematic review and meta‐analysis	2
Teratogenesis and the epigenetic programming of congenital defects: Why paternal exposures matter	2
Implications of abortion legislation on birth defect surveillance	2
The miR‐17‐92 cluster in cardiac health and disease	2
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Society for Birth Defects Research and Prevention Symposium: Health Disparities Within Communities of Color	2
Correction to Food Fortification Ineffective in Preventing Neural Tube Defects in India due to Regulation Promoting Inadequate Levels of Folic Acid and Vitamin B12	2
Review: Hormone Pregnancy Tests Were Teratogenic by the Same Failed Abortion and Hypoxia‐Related Mechanism as Misoprostol	2
Concomitant genetic defects potentiate the adverse impact of prenatal alcohol exposure on cardiac outflow tract maturation	2
Evaluation of gadolinium‐based contrast agents in pregnant CD‐1 mice and subsequent in utero exposure of the developing offspring, including behavioral evaluations	2
Evaluating endocrine disrupting chemicals: A perspective on the novel assessments in CLARITY‐BPA	2
BDR Reviewer Thank You	2
Integration and application of new approach methodologies in assessing the developmental hazards: Case study with an antimalarial drug	2
An example of parenchymal renal sparing in the context of complex malformations due to a novel mutation in the PBX1 gene	2
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Prevention and awareness of birth defects across the lifespan using examples from congenital heart defects and spina bifida	2
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COL1A1 regulates the apoptosis of embryonic stem cells by mediating the PITX1/TBX4 signaling	2
Risk factors and characteristics of the birth of patients with craniofacial microsomia, a case–control study	2
Reproductive and neurobehavioral effects of dinotefuran in an F1‐generation toxicity study in mice	2
Association of MTHFR (C677T, A1298C) and MTRR A66G polymorphisms with fatty acids profile and risk of neural tube defects	2
Animal evidence considered in determination of cannabis smoke and Δ9‐tetrahydrocannabinol as causing reproductive toxicity (developmental endpoint); Part I. Somatic development	2
Proportion of critical congenital heart defects attributable to unhealthy prepregnancy body mass index among women with live births in Florida, 2005–2016	2
Exome Sequencing to Identify Novel Susceptibility Genes for Nonsyndromic Split‐Hand/Ft Malformation: A Report From the National Birth Defects Prevention Study	2
Maternal hereditary hemolytic anemia and birth defects in the National Birth Defects Prevention Study	2
Prenatal epigenetic factors are predisposing for neurodevelopmental disorders—Considering placenta as a model	2
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Toward better assessments of developmental toxicity using stem cell‐based in vitro embryogenesis models	2
2021 U.S. Virgin Islands Zika health brigade: Providing recommended pediatric health screenings for children born to mothers with laboratory evidence of possible Zika virus infection during pregnancy	2
Cardiovascular function during early development is suppressed by cinnamon flavored, nicotine‐free, electronic cigarette vapor	2
Effect of tramadol hydrochloride on neural tube development in 48‐hr chick embryos: Argyrophilic nucleolar organizing region and genetic analysis study	2
Folate and vitamin B12 status and predicted neural tube defects risk among nonpregnant women of reproductive age from the Malawi National Micronutrient Survey, 2015–20	2
High‐throughput detection of craniofacial defects in fluorescent zebrafish	2
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Elucidating arrhythmogenic right ventricular cardiomyopathy with stem cells	2
A machine learning model for predicting congenital heart defects from administrative data	2
Investigation of the impact of AXL, TLR3, and STAT2 in congenital Zika syndrome through genetic polymorphisms and protein–protein interaction netw	2
Mechanical dissection and culture of mouse cranial neural crest cells	2
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Combined effects of maternal exposure to fungicides on behavioral development in F1‐generation mice: 3. Fixed‐dose study of imazalil	2
Docosahexaenoic acid, eicosapentaenoic acid, arachidonic acid, and neural tube defects in Tunisian population	2
HESI workshop summary: Interpretation of developmental and reproductive toxicity endpoints and the impact on data interpretation of adverse events	2
Co‐occurrence of congenital anomalies by maternal race/ethnicity among infants and fetuses with Down syndrome, 2013–2017: A U.S. population‐based analysis	2
Bladder augmentation in exstrophy vesicae: Long‐term results of a single experienced center	2
Childhood Educational Outcomes of Infants Born With Esophageal Atresia With or Without Tracheoesophageal Fistula	2
Functional Evaluation of Neural Tube Defect‐Related Missense Mutations Using In Silico Methods	2
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From the Editor‐in‐Chief: Birth Defects Research 2023	2
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Embryo‐Fetal Developmental Toxicity and Toxicokinetics Studies of YWS1903, a Novel Potassium‐Competitive Acid Blocker, in Pregnant Rats	1
Tetralogy of Fallot: Hypoxia, the villain of the story?	1
Development of a Thoracoscopic Model for Birth Defect Esophageal Atresia and Tracheoesophageal Fistula Using Fresh Sheep Tissues	1
Adverse Events After COVID‐19 Vaccination Between Pregnant and Nonpregnant Women	1
Biological and environmental factors influencing reproductive performance in ICR mice, Mus musculus	1
Alcohol exposure during pregnancy induces cardiac mitochondrial damage in offspring mice	1
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Climate Change and Congenital Anomalies: A Population‐Based Study of the Effect of Prolonged Extreme Heat Exposure on the Risk of Neural Tube Defects in France	1
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DNA methylation of the Lamin A/C gene is associated with congenital heart disease	1
Melatonin Attenuates PFOS‐Induced Reproductive Toxicity of Pregnant Mice due to Placental Damage Via Antioxidant, Anti‐Aging and Anti‐Inflammatory Pathways	1
Examining the Neurodevelopmental Impact of Sonic Hedgehog Pathway Inhibition in Mice	1
Updated EUROCAT guidelines for classification of cases with congenital anomalies	1