Birth Defects Research

Article	Citations
	79
Believing in science	32
Maternal cigarette smoking and alcohol consumption and congenital diaphragmatic hernia	29
Dolutegravir and rat whole embryo culture	27
Reply to Correspondence “Beyond Aggregate Risk: Drug‐ and Organ‐Specific Nuances in Counseling on Antidepressant Teratogenicity” (Tsai et al. 2025)	24
Protective Role of Vitamin B6 Against Teratogenic Effects Induced by Lead in Chick Embryo	24
Prenatal Exposure to Methamphetamine and Its Association With Birth Outcomes: A Meta‐Analysis	23
Developmental exposure to the flame retardant, triphenyl phosphate, causes long‐lasting neurobehavioral and neurochemical dysfunction	23
Community‐Engaged Research and the Use of Open Access ToxVal/ToxRef In Vivo Databases and New Approach Methodologies (NAM) to Address Human Health Risks From Environme	22
How Does Maternal Lipopolysaccharide Exposure Impact Prenatal Testicular Development in Rats, and Could α‐Tocopherol Provide a Protective Effect? A Histological, Immunohistochemical and Biochemical St	21
Domestic Use of Solvents and Pesticides and the Risk of Hypospadias in Offspring: A Case–Control Study From Brittany, France	21
Issue Information	19
Society for birth defects research and prevention's multidisciplinary research needs workshop 2022: A call to action	19
A Case Report: Co‐Occurrence of TNRC6B Gene Variant and Xq28 Microdeletion Syndrome With Comprehensive Literature Review	17
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Potential risk factors for hypospadias and negative correlation with DICER1 (rs3742330) A>G variant in Algerian population: A case‐control study	15
Reversible effects on female rat fertility with abrocitinib, a Janus kinase 1 inhibitor	15
Cannabidiol impairs neural tube closure in mouse whole embryo culture	15
In vitro fertilization and pregnancy outcomes of women with X chromosome abnormality: A case series	15
Why Has Gastroschisis Increased Over Time and Why Is It More Common in Infants of Young Mothers?	15
Emerging understanding of the effects of cannabis use during pregnancy	14
Using a health observance event to raise awareness: An assessment of World Birth Defects Day	14
Absence of developmental and reproductive toxicity in rats, rabbits, and zebrafish embryos exposed to antimalarial drug cabamiquine	13
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Transmission of behavioral and cognitive impairments across generations in rats subjected to prenatal valproic acid exposure	12
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Developmental toxicity induced by brodifacoum in zebrafish (Danio rerio) early life stages	12
A narrative review of exercise dose during pregnancy	12
Application of zebrafish in the study of craniomaxillofacial developmental anomalies	11
Developmental safety of nirmatrelvir in zebrafish (Danio rerio) embryos	11
Otocephaly Diagnosed Prenatally: A Case Study of a Rare Congenital Defect	11
Antifungal medication use during early pregnancy and the risk of congenital heart defects in the National Birth Defects Prevention Study, 1997–2011	11
Outcome of children with multicystic dysplastic kidney: Does involved side matter?	10
Issue Information	10
Prevalence of critical congenital heart defects and selected co‐occurring congenital anomalies, 2014–2018: A U.S. population‐based study	10
Prenatal diagnosis of SLC25A24 Fontaine progeroid syndrome: description of the fetal phenotype, genotype and detection of parental mosaicism	10
Assessing Environmental Risks Factors in Anorectal Malformations: Case Report and Literature Review	10
Identifying possible inaccuracy in reported birth head circumference measurements among infants in the US Zika Pregnancy and Infant Registry	10
A case of Williams syndrome with Wolff–Parkinson–White syndrome	10
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Evaluating the proportion of isolated cases among a spectrum of birth defects in a population‐based registry	10
A comparison of infants' birth defects self‐reported by mothers with data provided by general practitioners: Data from the Dutch Pregnancy Drug Register	10
Assessing the Readability, Credibility, and Accuracy of Online Vaccine Information for Pregnant and Lactating Individuals: A Cross‐Platform Analysis	10
Prevalence and Risk Factors of Pediatric Neurosurgical Congenital Anomalies at Mbeya Zonal Referral Hospital, Tanzania	9
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Malarial PI4K inhibitor induced diaphragmatic hernias in rat: Potential link with mammalian kinase inhibition	9
Publicly funded healthcare costs associated with orofacial clefts for children born in Alberta, Canada between 2002 and 2018	8
Ezh2‐dependent methylation in oral epithelia promotes secondary palatogenesis	8
Embryo‐fetal safety evaluation of ondansetron in rats	8
Juvenile toxicity study of PF‐07256472/recifercept, a recombinant human soluble fibroblast growth factor receptor 3, in 2–3‐month‐old cynomolgus monkeys	8
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MotherToBaby and CDC: Partnering to Provide a Rapid and Personalized Response to COVID‐19 Vaccine Inquiries During Pregnancy and Lactation	8
Translational potential of hiPSCs in predictive modeling of heart development and disease	8
Enhancing the Classification of Congenital Heart Defects for Outcome Association Studies in Birth Defects Registries	8
Valproic acid induced selective apoptosis of ocular fibrous tunic in mice fetuses	8
Issue Information	8
Use of vasoactive medications in pregnancy and the risk of stillbirth among birth defect cases	8
Prevalence of congenital anomalies in the Dutch Caribbean islands of Aruba, Bonaire, and Curaçao	8
An assessment of the reliability of 52 enhanced preliminary embryofetal development studies to detect developmental toxicity	7
Chloroacetonitrile reduces rat prenatal bone length and induces oxidative stress, apoptosis, and DNA damage in rat fetal liver	7
Birth defects surveillance: Working together to advance science	7
Correction to “Comments on “Maternal–fetal safety evaluation of an aqueous extract of Casearia sylvestris [AECS] leaves in rats” (Nagaoka et al., 2023 [DOI: 10.1002/bdr2.2	7
Correction to “Determination and analysis of sex ratios in heme oxygenase 1 gene targeted mouse embryos”	7
Determination and analysis of sex ratios in heme oxygenase 1 gene targeted mouse embryos	7
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Birth outcomes following in utero co‐exposure to tobacco and marijuana	7
Racial and ethnic differences in infant survival for hydrocephaly—Texas, 1999–2017	7
Effect of Nigella sativa Consumption During Pregnancy on Fertility, Morphological and Behaviors of Mice Offspring	7
A new 90‐day drinking water study of sodium cyanide in rats to further evaluate National Toxicology Program findings and inform risk assessment	7
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Post‐mortem rapid aneuploidy testing for holoprosencephaly	7
Issue Information	7
Intake of Trans‐Fat Diet With Prenatal Bisphenol A Exposure Induce Global DNA Methylation in Rats Offspring	7
The outcome and complications of modern staged repair surgery in newborns with classic bladder exstrophy in different genders: A retrospective study	6

Periconceptional use of vitamin A and the risk of giving birth to a child with nonsyndromic orofacial clefts—A meta‐analysis	6
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2022	6
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Hypothesized pathogenesis of acardius acephalus, acormus, amorphus, anceps, acardiac edema, single umbilical artery, and pump twin risk prediction	6
Survival of Children With Critical Congenital Heart Defects in the National Birth Defects Prevention Study	6
Knowledge of periconceptional folic acid supplementation and associated factors among pregnant women attending antenatal care at public health facilities in Hawassa, South Ethiopia	6
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2020: 30‐Year anniversary of gaining knowledge about folic acid's prevention potential for ne	6
Paternal Valproate Treatment and Risk of Childhood Neurodevelopmental Disorders: Precautionary Regulatory Measures Are Insufficiently Substantiated	6
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World health assembly resolution for preventing micronutrient deficiencies and associated neural tube defects—A case study of global partnerships for a successful resolution adoption	6
Rodent anogenital distance recommendations	6
Associations between maternal reports of periconceptional fever from miscellaneous causes and structural birth defects	6
Sex‐dependent alterations of inflammatory factors, oxidative stress, and histopathology of the brain‐gut axis in a VPA‐induced autistic‐like model of rats	6
Protective effect of Agaricus bisporus mushroom against maternal and fetal damage induced by lead administration during pregnancy in rats	6
PTBP3 Associated With 9q32 Locus Is a Candidate Gene for Nager Syndrome	6
Ascertainment of malformations in pregnancy registries: Lessons learned in the North American AED Pregnancy Registry	6
Comparative anatomy, pre‐ and postnatal changes during the development and maturation of the small intestine: Life‐stage influences on exposure	5
Maternal Exposure to Tap Water Disinfection By‐Products and Risk of Selected Congenital Heart Defects	5
Prenatal alcohol exposure can be determined from baby teeth: Proof of concept	5
Blastocyst Cavity Expansion Promotes Cell Polarization During Early Development of Mouse Embryos	5
Homozygous LOXL2 variant in individuals affected by non‐syndromic occipital encephalocele	5
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Risk of birth defects by pregestational type 1 or type 2 diabetes: National Birth Defects Prevention Study, 1997–2011	5
Recommendation to change the peer review process	5
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A Generalized Machine Learning Model for Identifying Congenital Heart Defects (CHDs) Using ICD Codes	5
Assessment of postnatal femur development in Wistar Han rats	5
Maternal exposure to heparin products and risk of birth defects in the National Birth Defects Prevention Study	5
Temporal Trends of Infant Mortality Secondary to Congenital Heart Disease: National CDC Cohort Analysis (1999–2020)	5
Revisiting the testicular toxicity of cyanide: Assessment of the new and existing literature	5
Issue Information	5
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Gestational exposure to continuous light impairs the development of the female reproductive system in adult Wistar rat offspring	5
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Life Course Considerations in Environmental Health: Developmental Neurotoxicity of Domoic Acid at Doses Below Acute Effect Levels in Adult Humans	5
Impact of TMPRSS6 Genetic Variants on Maternal Iron Status in Pregnancy: A Systematic Review	5
Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring	5
Comparing Folic Acid Interventions and Arsenic Reduction Strategies for Neural Tube Defect Prevention in Bangladesh: A Systematic Review and Decision Analysis	5
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Sodium valproate exposure influences the expression of pparg in the zebrafish model	5
Multiple subtypes of coxsackievirus group B can cause congenital heart disease	5
Population‐based surveillance for birth defects potentially related to Zika virus infection including 3‐year mortality and developmental outcomes, and Early Intervention Program service use—New York C	5
Maternal Separation Exhibits a Sex Dimorphism in Memory Impairments in Adolescent Rats: Acute Methylphenidate Administration as a Treatment	5
Beyond Aggregate Risk: Drug‐ and Organ‐Specific Nuances in Counseling on Antidepressant Teratogenicity	4
Mycophenolate mofetil exposure on embryonic and fetal ear development in rats during pregnancy	4
Issue Information	4
The association of nausea and vomiting of pregnancy, its treatments, and select birth defects: Findings from the National Birth Defect Prevention Study	4
Early pregnancy vitamin D status and risk of select congenital anomalies in the National Birth Defects Prevention Study	4
Climate and environmental changes exacerbate health disparities in pregnant people and their offspring. How can we protect women and their babies?	4
Factors associated with Medicaid participation among infants born with birth defects in Texas, 2010–2014	4
Reproductive and neurobehavioral effects of maternal exposure to dinotefuran in the F1‐generation mice	4
Association Between Self‐Reported Infections and Seropositivity Among Pregnant Women With Gastroschisis: A Case Control Study, With Emphasis on Chlamydia trachomatis	4
Epigenetic regulation of craniofacial development and disease	4
Issue Information	4
Maternal diabetes as a teratogenic factor for congenital heart defects in infants of diabetic mothers	4
Review of the state of science and evaluation of currently available in silico prediction models for reproductive and developmental toxicity: A case study on pesticides	4
Hdac1 and Hdac2 positively regulate Notch1 gain‐of‐function pathogenic signaling in committed osteoblasts of male mice	4
Gestational exposure to triphenyl phosphate induces epigenetic modifications in C57Bl/6 fetal liver	4
Subdivided Historical Data to Assess Replicability of the Rat Embryo‐Fetal Developmental Toxicity Study	4
A multi‐program analysis of cleft lip with cleft palate prevalence and mortality using data from 22 International Clearinghouse for Birth Defects Surveillance and Research programs, 1974–2014	4
A case‐control study characterizing polydactyly risk factors in Bogotá and Cali, Colombia between 2002 and 2020	4
A Supra‐Numerary Limb Grafted Onto a Sacrococcygeal Mass in a Child With Spinal Dysraphism: Case Report, Dysmorphogenesis, and Management Review	4
Protective effect of quercetin on fetal development and congenital skeletal anomalies against exposure of pregnant Wistar rats to crude oil vapor	4
Hypothesis: By‐products of vascular disruption carried in the CSF affect prenatal brain development	4
Maternal Age‐Related Gender Bias in Trisomy 21 and Trisomy 18	4
The prenatal use of agmatine prevents social behavior deficits in VPA‐exposed mice by activating the ERK/CREB/BDNF signaling pathway	4
Analysis of incidence data in developmental toxicity studies: Statistical tests to account for litter effects in fetal defect data	4
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In‐utero cannabis exposure and long‐term psychiatric and neurodevelopmental outcomes: The limitations of existing literature and recommendations for future research	4
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The relationship between maternal periconceptional micronutrient supplementation and non‐syndromic cleft lip/palate in offspring	3
Implications of abortion legislation on birth defect surveillance	3
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries	3
Docosahexaenoic acid, eicosapentaenoic acid, arachidonic acid, and neural tube defects in Tunisian population	3
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Association of MTHFR (C677T, A1298C) and MTRR A66G polymorphisms with fatty acids profile and risk of neural tube defects	3
A putative adverse outcome network for neonatal mortality and lower birth weight in rodents: Applicability to per‐ and polyfluoroalkyl substances and relevance to human health	3
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Daphne Trasler: In memoriam	3
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Maternal hereditary hemolytic anemia and birth defects in the National Birth Defects Prevention Study	3
Vitelline vascular remnant causing intestinal obstruction in a patient with TARP syndrome	3
Measurement of Androgen‐Sensitive Preweaning Developmental Landmarks in Rodents: Best Practices and Toxicological Significance	3
Prophylactic use of cardiac medications for delay of left ventricular dysfunction in Duchenne muscular dystrophy	3
Investigating the association between vitamin D dietary intake during pregnancy and incidence of clubfoot in neonates	3
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Factors associated with infant sex and preterm birth status for selected birth defects from the National Birth Defects Prevention Study, 1997–2011	3
Conjoined twins and conjoined triplets: At the heart of the matter	3
Observed Prevalence of Congenital Situs Inversus in the United States Before and During the SARS‐CoV‐2 Pandemic, 2017–2022	3
Additional evidence for the vascular disruption defect hypothesis in a novel case of brainstem disconnection syndrome	3
Issue Information	3
Bladder augmentation in exstrophy vesicae: Long‐term results of a single experienced center	3
The timing, duration, and severity of nausea and vomiting of pregnancy and adverse birth outcomes among controls without birth defects in the National Birth Defects Prevention Study	3
Issue Information	3
Is gastroschisis associated with county‐level socio‐environmental quality during pregnancy?	3
Risks of Birth Defects Following In Utero Exposures to Unregulated Brominated Haloacetic Acids	3
Describing characteristics of adults with and without congenital heart defects hospitalized with COVID‐19	3
Prevalence of neural tube defects, maternal HIV status, and antiretroviral therapy from a hospital‐based birth defect surveillance in Kampala, Uganda	3
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Natural history study of Pseudoachondroplasia: A focus on oral health	3
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Genitourinary infection and gastroschisis: A systematic review and meta‐analysis	3
Gastroschisis prevalence patterns in 27 surveillance programs from 24 countries, International Clearinghouse for Birth Defects Surveillance and Research, 1980–2017	3
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High glucose impairs osteogenic differentiation of embryonic stem cells via early diversion of beta‐catenin from Forkhead box O to T cell factor interaction	3
Risk factors and characteristics of the birth of patients with craniofacial microsomia, a case–control study	3
Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues	3
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Neighborhood social deprivation and healthcare utilization, disability, and comorbidities among young adults with congenital heart defects: Congenital heart survey to recognize outcomes, needs, and we	3
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Early childhood outcomes of NICU graduates with cytomegalovirus infection in California	3
Regulation of Oct4 in stem cells and neural crest cells	3
Pregnancy and infant outcomes by trimester of SARS‐CoV‐2 infection in pregnancy–SET‐NET, 22 jurisdictions, January 25, 2020–December 31, 2020	3