Birth Defects Research

Article	Citations
	95
Believing in science	30
Protective Role of Vitamin B6 Against Teratogenic Effects Induced by Lead in Chick Embryo	29
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Reply to Correspondence “Beyond Aggregate Risk: Drug‐ and Organ‐Specific Nuances in Counseling on Antidepressant Teratogenicity” (Tsai et al. 2025)	26
Prenatal Exposure to Methamphetamine and Its Association With Birth Outcomes: A Meta‐Analysis	25
How Does Maternal Lipopolysaccharide Exposure Impact Prenatal Testicular Development in Rats, and Could α‐Tocopherol Provide a Protective Effect? A Histological, Immunohistochemical and Biochemical St	25
Community‐Engaged Research and the Use of Open Access ToxVal/ToxRef In Vivo Databases and New Approach Methodologies (NAM) to Address Human Health Risks From Environme	25
Domestic Use of Solvents and Pesticides and the Risk of Hypospadias in Offspring: A Case–Control Study From Brittany, France	24
Maternal cigarette smoking and alcohol consumption and congenital diaphragmatic hernia	22
Society for birth defects research and prevention's multidisciplinary research needs workshop 2022: A call to action	21
Developmental exposure to the flame retardant, triphenyl phosphate, causes long‐lasting neurobehavioral and neurochemical dysfunction	20
A Case Report: Co‐Occurrence of TNRC6B Gene Variant and Xq28 Microdeletion Syndrome With Comprehensive Literature Review	19
Issue Information	18
In vitro fertilization and pregnancy outcomes of women with X chromosome abnormality: A case series	17
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Reversible effects on female rat fertility with abrocitinib, a Janus kinase 1 inhibitor	16
Why Has Gastroschisis Increased Over Time and Why Is It More Common in Infants of Young Mothers?	16
Potential risk factors for hypospadias and negative correlation with DICER1 (rs3742330) A>G variant in Algerian population: A case‐control study	16
Using a health observance event to raise awareness: An assessment of World Birth Defects Day	15
Emerging understanding of the effects of cannabis use during pregnancy	15
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Developmental toxicity induced by brodifacoum in zebrafish (Danio rerio) early life stages	13
Absence of developmental and reproductive toxicity in rats, rabbits, and zebrafish embryos exposed to antimalarial drug cabamiquine	13
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Transmission of behavioral and cognitive impairments across generations in rats subjected to prenatal valproic acid exposure	13
Antifungal medication use during early pregnancy and the risk of congenital heart defects in the National Birth Defects Prevention Study, 1997–2011	12
Developmental safety of nirmatrelvir in zebrafish (Danio rerio) embryos	12
Evaluating the proportion of isolated cases among a spectrum of birth defects in a population‐based registry	12
Otocephaly Diagnosed Prenatally: A Case Study of a Rare Congenital Defect	12
Cannabidiol impairs neural tube closure in mouse whole embryo culture	11
Assessing Environmental Risks Factors in Anorectal Malformations: Case Report and Literature Review	11
Prenatal diagnosis of SLC25A24 Fontaine progeroid syndrome: description of the fetal phenotype, genotype and detection of parental mosaicism	11
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Outcome of children with multicystic dysplastic kidney: Does involved side matter?	11
A narrative review of exercise dose during pregnancy	11
Application of zebrafish in the study of craniomaxillofacial developmental anomalies	11
Prevalence of critical congenital heart defects and selected co‐occurring congenital anomalies, 2014–2018: A U.S. population‐based study	10
Prevalence and Risk Factors of Pediatric Neurosurgical Congenital Anomalies at Mbeya Zonal Referral Hospital, Tanzania	10
A case of Williams syndrome with Wolff–Parkinson–White syndrome	10
Malarial PI4K inhibitor induced diaphragmatic hernias in rat: Potential link with mammalian kinase inhibition	10
Issue Information	10
A comparison of infants' birth defects self‐reported by mothers with data provided by general practitioners: Data from the Dutch Pregnancy Drug Register	10
Identifying possible inaccuracy in reported birth head circumference measurements among infants in the US Zika Pregnancy and Infant Registry	10
Assessing the Readability, Credibility, and Accuracy of Online Vaccine Information for Pregnant and Lactating Individuals: A Cross‐Platform Analysis	10
MotherToBaby and CDC: Partnering to Provide a Rapid and Personalized Response to COVID‐19 Vaccine Inquiries During Pregnancy and Lactation	9
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Publicly funded healthcare costs associated with orofacial clefts for children born in Alberta, Canada between 2002 and 2018	9
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Ezh2‐dependent methylation in oral epithelia promotes secondary palatogenesis	8
Use of vasoactive medications in pregnancy and the risk of stillbirth among birth defect cases	8
Determination and analysis of sex ratios in heme oxygenase 1 gene targeted mouse embryos	8
Issue Information	8
Juvenile toxicity study of PF‐07256472/recifercept, a recombinant human soluble fibroblast growth factor receptor 3, in 2–3‐month‐old cynomolgus monkeys	8
Enhancing the Classification of Congenital Heart Defects for Outcome Association Studies in Birth Defects Registries	8
An assessment of the reliability of 52 enhanced preliminary embryofetal development studies to detect developmental toxicity	8
Translational potential of hiPSCs in predictive modeling of heart development and disease	8
Embryo‐fetal safety evaluation of ondansetron in rats	8
A new 90‐day drinking water study of sodium cyanide in rats to further evaluate National Toxicology Program findings and inform risk assessment	8
Valproic acid induced selective apoptosis of ocular fibrous tunic in mice fetuses	8
Prevalence of congenital anomalies in the Dutch Caribbean islands of Aruba, Bonaire, and Curaçao	7
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Effects of Pre‐Conception Stress and Dracocephalum moldavica Extract on Sperm Parameters and Sex Hormones in Parents and Offspring	7
Issue Information	7
Post‐mortem rapid aneuploidy testing for holoprosencephaly	7
Birth outcomes following in utero co‐exposure to tobacco and marijuana	7
Birth defects surveillance: Working together to advance science	7
Correction to “Comments on “Maternal–fetal safety evaluation of an aqueous extract of Casearia sylvestris [AECS] leaves in rats” (Nagaoka et al., 2023 [DOI: 10.1002/bdr2.2	7
Correction to “Determination and analysis of sex ratios in heme oxygenase 1 gene targeted mouse embryos”	7
Chloroacetonitrile reduces rat prenatal bone length and induces oxidative stress, apoptosis, and DNA damage in rat fetal liver	7
Intake of Trans‐Fat Diet With Prenatal Bisphenol A Exposure Induce Global DNA Methylation in Rats Offspring	7
Racial and ethnic differences in infant survival for hydrocephaly—Texas, 1999–2017	7
Effect of Nigella sativa Consumption During Pregnancy on Fertility, Morphological and Behaviors of Mice Offspring	7
Periconceptional use of vitamin A and the risk of giving birth to a child with nonsyndromic orofacial clefts—A meta‐analysis	6
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2022	6

Survival of Children With Critical Congenital Heart Defects in the National Birth Defects Prevention Study	6
Recommendation to change the peer review process	6
World health assembly resolution for preventing micronutrient deficiencies and associated neural tube defects—A case study of global partnerships for a successful resolution adoption	6
Rodent anogenital distance recommendations	6
Knowledge of periconceptional folic acid supplementation and associated factors among pregnant women attending antenatal care at public health facilities in Hawassa, South Ethiopia	6
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Paternal Valproate Treatment and Risk of Childhood Neurodevelopmental Disorders: Precautionary Regulatory Measures Are Insufficiently Substantiated	6
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Sodium valproate exposure influences the expression of pparg in the zebrafish model	6
Ascertainment of malformations in pregnancy registries: Lessons learned in the North American AED Pregnancy Registry	6
Issue Information	6
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Associations between maternal reports of periconceptional fever from miscellaneous causes and structural birth defects	6
PTBP3 Associated With 9q32 Locus Is a Candidate Gene for Nager Syndrome	6
Sex‐dependent alterations of inflammatory factors, oxidative stress, and histopathology of the brain‐gut axis in a VPA‐induced autistic‐like model of rats	6
Multiple subtypes of coxsackievirus group B can cause congenital heart disease	6
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2020: 30‐Year anniversary of gaining knowledge about folic acid's prevention potential for ne	6
Gestational exposure to continuous light impairs the development of the female reproductive system in adult Wistar rat offspring	6
The outcome and complications of modern staged repair surgery in newborns with classic bladder exstrophy in different genders: A retrospective study	6
Population‐based surveillance for birth defects potentially related to Zika virus infection including 3‐year mortality and developmental outcomes, and Early Intervention Program service use—New York C	6
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Protective effect of Agaricus bisporus mushroom against maternal and fetal damage induced by lead administration during pregnancy in rats	5
Maternal Exposure to Tap Water Disinfection By‐Products and Risk of Selected Congenital Heart Defects	5
Impact of TMPRSS6 Genetic Variants on Maternal Iron Status in Pregnancy: A Systematic Review	5
Issue Information	5
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Prenatal alcohol exposure can be determined from baby teeth: Proof of concept	5
Mycophenolate mofetil exposure on embryonic and fetal ear development in rats during pregnancy	5
Protective effect of quercetin on fetal development and congenital skeletal anomalies against exposure of pregnant Wistar rats to crude oil vapor	5
Risk of birth defects by pregestational type 1 or type 2 diabetes: National Birth Defects Prevention Study, 1997–2011	5
Life Course Considerations in Environmental Health: Developmental Neurotoxicity of Domoic Acid at Doses Below Acute Effect Levels in Adult Humans	5
Comparative anatomy, pre‐ and postnatal changes during the development and maturation of the small intestine: Life‐stage influences on exposure	5
Issue Information	5
Issue Information	5
Association Between Self‐Reported Infections and Seropositivity Among Pregnant Women With Gastroschisis: A Case Control Study, With Emphasis on Chlamydia trachomatis	5
Beyond Aggregate Risk: Drug‐ and Organ‐Specific Nuances in Counseling on Antidepressant Teratogenicity	5
Maternal exposure to heparin products and risk of birth defects in the National Birth Defects Prevention Study	5
A Supra‐Numerary Limb Grafted Onto a Sacrococcygeal Mass in a Child With Spinal Dysraphism: Case Report, Dysmorphogenesis, and Management Review	5
Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring	5
Maternal Separation Exhibits a Sex Dimorphism in Memory Impairments in Adolescent Rats: Acute Methylphenidate Administration as a Treatment	5
Assessment of postnatal femur development in Wistar Han rats	5
A Generalized Machine Learning Model for Identifying Congenital Heart Defects (CHDs) Using ICD Codes	5
Blastocyst Cavity Expansion Promotes Cell Polarization During Early Development of Mouse Embryos	5
Homozygous LOXL2 variant in individuals affected by non‐syndromic occipital encephalocele	5
Temporal Trends of Infant Mortality Secondary to Congenital Heart Disease: National CDC Cohort Analysis (1999–2020)	5
Revisiting the testicular toxicity of cyanide: Assessment of the new and existing literature	5
Issue Information	4
Comparing Folic Acid Interventions and Arsenic Reduction Strategies for Neural Tube Defect Prevention in Bangladesh: A Systematic Review and Decision Analysis	4
Epigenetic regulation of craniofacial development and disease	4
A case‐control study characterizing polydactyly risk factors in Bogotá and Cali, Colombia between 2002 and 2020	4
Gestational exposure to triphenyl phosphate induces epigenetic modifications in C57Bl/6 fetal liver	4
Climate and environmental changes exacerbate health disparities in pregnant people and their offspring. How can we protect women and their babies?	4
Maternal Age‐Related Gender Bias in Trisomy 21 and Trisomy 18	4
The prenatal use of agmatine prevents social behavior deficits in VPA‐exposed mice by activating the ERK/CREB/BDNF signaling pathway	4
Issue Information	4
In‐utero cannabis exposure and long‐term psychiatric and neurodevelopmental outcomes: The limitations of existing literature and recommendations for future research	4
Reproductive and neurobehavioral effects of maternal exposure to dinotefuran in the F1‐generation mice	4
Subdivided Historical Data to Assess Replicability of the Rat Embryo‐Fetal Developmental Toxicity Study	4
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The association of nausea and vomiting of pregnancy, its treatments, and select birth defects: Findings from the National Birth Defect Prevention Study	4
Pregnancy and infant outcomes by trimester of SARS‐CoV ‐2 infection in pregnancy– SET‐NET , 22 jur	4
Review of the state of science and evaluation of currently available in silico prediction models for reproductive and developmental toxicity: A case study on pesticides	4
Factors associated with Medicaid participation among infants born with birth defects in Texas, 2010–2014	4
Issue Information	4
A multi‐program analysis of cleft lip with cleft palate prevalence and mortality using data from 22 International Clearinghouse for Birth Defects Surveillance and Research programs, 1974–2014	4
Analysis of incidence data in developmental toxicity studies: Statistical tests to account for litter effects in fetal defect data	4
Maternal diabetes as a teratogenic factor for congenital heart defects in infants of diabetic mothers	4
Hypothesis: By‐products of vascular disruption carried in the CSF affect prenatal brain development	4
Early pregnancy vitamin D status and risk of select congenital anomalies in the National Birth Defects Prevention Study	4
Hdac1 and Hdac2 positively regulate Notch1 gain‐of‐function pathogenic signaling in committed osteoblasts of male mice	4
Additional evidence for the vascular disruption defect hypothesis in a novel case of brainstem disconnection syndrome	3
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Issue Information	3
Gastroschisis prevalence patterns in 27 surveillance programs from 24 countries, International Clearinghouse for Birth Defects Surveillance and Research, 1980–2017	3
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Observed Prevalence of Congenital Situs Inversus in the United States Before and During the SARS‐CoV‐2 Pandemic, 2017–2022	3
A Case of a Fetus With SETD5 Mutation: Prenatal Phenotype and Literature Review	3
Natural history study of Pseudoachondroplasia: A focus on oral health	3
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Describing characteristics of adults with and without congenital heart defects hospitalized with COVID‐19	3

Bladder augmentation in exstrophy vesicae: Long‐term results of a single experienced center	3
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Investigation of the impact of AXL, TLR3, and STAT2 in congenital Zika syndrome through genetic polymorphisms and protein–protein interaction netw	3
Prophylactic use of cardiac medications for delay of left ventricular dysfunction in Duchenne muscular dystrophy	3
Genitourinary infection and gastroschisis: A systematic review and meta‐analysis	3
Measurement of Androgen‐Sensitive Preweaning Developmental Landmarks in Rodents: Best Practices and Toxicological Significance	3
Conjoined twins and conjoined triplets: At the heart of the matter	3
Risk factors and characteristics of the birth of patients with craniofacial microsomia, a case–control study	3
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Implications of abortion legislation on birth defect surveillance	3
Vitelline vascular remnant causing intestinal obstruction in a patient with TARP syndrome	3
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Factors associated with infant sex and preterm birth status for selected birth defects from the National Birth Defects Prevention Study, 1997–2011	3
Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues	3
Investigating the association between vitamin D dietary intake during pregnancy and incidence of clubfoot in neonates	3
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Risks of Birth Defects Following In Utero Exposures to Unregulated Brominated Haloacetic Acids	3
Docosahexaenoic acid, eicosapentaenoic acid, arachidonic acid, and neural tube defects in Tunisian population	3
Issue Information	3
Prenatal epigenetic factors are predisposing for neurodevelopmental disorders—Considering placenta as a model	3
Is gastroschisis associated with county‐level socio‐environmental quality during pregnancy?	3
Association of MTHFR (C677T, A1298C) and MTRR A66G polymorphisms with fatty acids profile and risk of neural tube defects	3
The timing, duration, and severity of nausea and vomiting of pregnancy and adverse birth outcomes among controls without birth defects in the National Birth Defects Prevention Study	3
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Maternal hereditary hemolytic anemia and birth defects in the National Birth Defects Prevention Study	3
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Neighborhood social deprivation and healthcare utilization, disability, and comorbidities among young adults with congenital heart defects: Congenital heart survey to recognize outcomes, needs, and we	3
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Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries	3
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High glucose impairs osteogenic differentiation of embryonic stem cells via early diversion of beta‐catenin from Forkhead box O to T cell factor interaction	3
The relationship between maternal periconceptional micronutrient supplementation and non‐syndromic cleft lip/palate in offspring	3
A putative adverse outcome network for neonatal mortality and lower birth weight in rodents: Applicability to per‐ and polyfluoroalkyl substances and relevance to human health	3
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Early childhood outcomes of NICU graduates with cytomegalovirus infection in California	3
Regulation of Oct4 in stem cells and neural crest cells	3