APL Bioengineering

Article	Citations
Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair	78
Synergy between photonics and biological approaches—A review of combination therapies for cancer theranostics	75
Scheduled dosage regimen by irreversible electroporation of loaded erythrocytes for cancer treatment	71
Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway	65
The yellow brick road to nuclear membrane mechanotransduction	43
Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome	39
Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus	37
Aqueous electrolyte-gated solution-processed metal oxide transistors for direct cellular interfaces	35
Engineering CAR T cells for enhanced efficacy and safety	31
A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces	31
Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration	31
Black phosphorus-enhanced injectable hydrogel for infected soft tissue healing	30
Electrophysiological features of cortical 3D networks are deeply modulated by scaffold properties	27
Evaluation of chromatin mesoscale organization	26
3D bioprinted human iPSC-derived neural progenitor cells as a novel platform for studying neurogenic niche	25
Geometrically engineered organoid units and their assembly for pre-construction of organ structures	25
Exploring the translational impact of type 1 diabetes on cerebral neurovascular function through ECoG-LSCI	24
Unpleasant odors compared to pleasant ones cause higher cortical activations detectable by fNIRS and observable mostly in females	23
Computational modeling of the physical features that influence breast cancer invasion into adipose tissue	23
The mechanobiology of nuclear phase separation	22
GelMA micropattern enhances cardiomyocyte organization, maturation, and contraction via contact guidance	22
Machine learning-informed predictions of nanoparticle mobility and fate in the mucus barrier	21
A fully automated deep learning approach for coronary artery segmentation and comprehensive characterization	21
Model discovery approach enables noninvasive measurement of intra-tumoral fluid transport in dynamic MRI	20
Fibroblast senescence-associated extracellular matrix promotes heterogeneous lung niche	20

A novel portable in situ printer for hydrogel multi-structure molding and cell printing	20
Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges	19
Learning discrete structures for cancer radiomics	19
A comprehensive review of graphene-based biosensors: Fabrication, applications, characterization and future perspectives—A review	18
Degradation-aware neural imputation: Advancing decoding stability in brain machine interfaces	18
The role of biomechanical factors in models of intervertebral disc degeneration across multiple length scales	18
Non-contact radiofrequency stimulation to the olfactory nerve of human subjects	18
Orthopedic meta-implants	17
Mechanism study on the influences of buffer osmotic pressure on microfluidic chip-based cell electrofusion	17
M/EEG source localization for both subcortical and cortical sources using a convolutional neural network with a realistic head conductivity model	17
Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes	17
Immunogenic cell death-related cancer-associated fibroblast clusters and prognostic risk model in cervical cancer	17
Advancements in textile techniques for cardiovascular tissue replacement and repair	17
Fluorescence spectroscopy as a novel tool in hematological diagnostics	16
TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis	15
Differential effects of vascular endothelial growth factor on glycocalyx of endothelial and tumor cells and potential targets for tumor metastasis	15
Terahertz in vivo imaging of human skin: Toward detection of abnormal skin pathologies	15
Advanced biomaterial strategies for overcoming age-associated wound healing impairments	15
A review: Blood pressure monitoring based on PPG and circadian rhythm	15
Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels	14
Regulation of airway remodeling in asthma: The synergistic effects of nanotechnology and Hippo pathway activation	14
CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays	14
Injectable photosensitive bone cement enhancing angiogenesis and osteogenic differentiation for the treatment of bone nonunion	14
Mechanical cues orchestrate monocyte behavior in immune regulation and disease	13
Altered blood flow due to larger aortic diameters in patients with transcatheter heart valve thrombosis	13
Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects	13
Long-term effect of sodium selenite on the integrity and permeability of on-chip microvasculature	13
In vivo label-free tissue histology through a microstructured imaging window	13
Bioengineering of the liver	12
Quercetin targets the Ccl4–Ccr5 axis to relieve neuropathic pain after spinal cord injury	12
Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system	12
The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment	12
Investigations on artificially extending the spectral range of natural vision	12
Publisher's Note: “Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler” [APL Bioeng. 6, 036102 (2022)]	12
Fluid flow to mimic organ function in 3D in vitro models	12
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology	11
Collagen density regulates tip–stalk cell rearrangement during angiogenesis via cellular bioenergetics	11
Single-pericyte nanomechanics measured by contraction cytometry	11
Mechanobiology of the cell nucleus	11
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing	11
Biosensors integrated within wearable devices for monitoring chronic wound status	11
Photoplethysmography-based HRV analysis and machine learning for real-time stress quantification in mental health applications	10
Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells	10
Modeling nitric oxide diffusion and plasticity modulation in cerebellar learning	10
Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo	10
Hemodynamics of thrombus formation in intracranial aneurysms: An in silico observational study	10
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins	10
A high throughput cell stretch device for investigating mechanobiology in vitro	10
High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array	10
Magnetic self-assembly of 3D multicellular microscaffolds: A biomimetic brain tumor-on-a-chip for drug delivery and selectivity testing	10

PEDOT:PSS-coated platinum electrodes for neural stimulation	9
Engineering approaches for understanding mechanical memory in cancer metastasis	9
Epigenetic regulation and mechanobiological adaptation in tenocytes during maturation	9
Surface electromyography using dry polymeric electrodes	9
Rapid flowing cells localization enabled by spatiotemporal manipulation of their holographic patterns	9
Engineered matrix microenvironments reveal the heterogeneity of liver sinusoidal endothelial cell phenotypic responses	9
Cerebellar contribution to multisensory integration: A computational modeling exploration	9
Stem cell mechanoadaptation. II. Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling	9
Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation	9
Publisher's Note: “Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility” [APL Bioeng. 7, 036113 (2023)]	9
Burst sine wave electroporation (B-SWE) for expansive blood–brain barrier disruption and controlled non-thermal tissue ablation for neurological disease	9
Imaging of the vascular distribution of the outer ear using optical coherence tomography angiography for highly accurate positioning of a hearable sensor	9
3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells	8
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells	8
Mutual antagonism between CD44 and integrins in glioblastoma cell traction and migration	8
The mechanobiology of fibroblast activation in disease	8
Low-intensity pulsed ultrasound irradiation ameliorates gut inflammation and neuroinflammation in mice with DSS-induced colitis	8
All-in-one properties of an anticancer-covered airway stent for the prevention of malignant central airway obstruction	8
Drug/gene delivery and theranostics	8
Fluid shear stress induced-endothelial phenotypic transition contributes to cerebral ischemia–reperfusion injury and repair	8
GelMA-glycol chitosan hydrogels for cartilage regeneration: The role of uniaxial mechanical stimulation in enhancing mechanical, adhesive, and biochemical properties	8
Mechanobiological engineering strategies for organoid culture	8
Wearable devices for continuous monitoring of biosignals: Challenges and opportunities	8
Silk fibroin promotes H3K9me3 expression and chromatin reorganization to regulate endothelial cell proliferation	8
Generation of direct current electrical fields as regenerative therapy for spinal cord injury: A review	8
Mechanoimmunology: Are inflammatory epigenetic states of macrophages tuned by biophysical factors?	7
Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids	7
Application of instant assembly of collagen to bioprint cardiac tissues	7
A multi-scale numerical approach to study monoclonal antibodies in solution	7
Studying the roles of salt ions in the pore initiation and closure stages in the biomembrane electroporation	7
Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design	7
Investigating cartilage-related diseases by polarization-resolved second harmonic generation (P-SHG) imaging	7
Structure–function relationships for squid skin-inspired wearable thermoregulatory materials	7
Guest Editorial: Structure and mechanics of biofluids, biomaterials, and biologics	7
Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow	7
Optimization frameworks for bespoke sensory encoding in neuroprosthetics	7
Human gut epithelium features recapitulated in MINERVA 2.0 millifluidic organ-on-a-chip device	7
Metronomic photodynamic therapy for deep organ cancer by implantable wireless OLEDs	7
Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model	7
Publisher's Note: “Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design” [APL Bioeng. 7, 046109 (2023)]	7
IgG and IgM differentiation in a particle-based agglutination assay by control over antigen surface density	7
Long-term day-by-day tracking of microvascular networks sprouting in fibrin gels: From detailed morphological analyses to general growth rules	6
A modular and reconfigurable microfluidic device for culturing spheroids under continuous perfusion	6
Publisher's Note: “Magnetic force-based cell manipulation for in vitro tissue engineering” [APL Bioeng. 7, 031504 (2023)]	6
Editorial Series conclusion and journal outlook	6
Apoptosis-associated genetic mechanisms in the transition from rheumatoid arthritis to osteoporosis: A bioinformatics and functional analysis approach	6
3D confinement alters smooth muscle cell responses to chemical and mechanical cues	6
Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility	6
Highly stretchable and sensitive silicone composites with positive piezoconductivity using nickel powder and ionic liquid	6
Investigating the reliability of the evoked response in human iPSCs-derived neuronal networks coupled to micro-electrode arrays	6
Skin-on-chip: Quo vadis?	6
Evaluation of screw pull-out from plate fixation of en bloc distal radius resection with ulnar reconstruction: Finite element analysis and comparison with experiments on Thiel cadavers	6
Multifunctional scaffolds for biomedical applications: Crafting versatile solutions with polycaprolactone enriched by graphene oxide	6
User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium	6
On the nuclear pore complex and its emerging role in cellular mechanotransduction	6
Gold nanorods with iron oxide dual-modal bioprobes in SERS-MRI enable accurate programmed cell death ligand-1 expression detection in triple-negative breast cancer	6
Hydrodynamic efficient cell capture and pairing method on microfluidic cell electrofusion chip	6
Post-stroke spontaneous motor recovery in mice can be predicted from acute-phase local field potential using machine learning	5
AI-aided holographic flow cytometry for label-free identification of ovarian cancer cells in the presence of unbalanced datasets	5
A fully implantable sensorized artificial urinary bladder to restore continence and fullness monitoring	5
Functional analysis of human brain endothelium using a microfluidic device integrating a cell culture insert	5
Elastocapillary effects determine early matrix deformation by glioblastoma cell spheroids	5
Applying physical principles to cancer research	5
Peptide coacervates as intracellular delivery vehicles for synergistic cancer photothermal- and chemo-therapies	5
The effect of chronic kidney disease on tissue formation of in situ tissue-engineered vascular grafts	5
Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts	5
Electrical aspects of skin as a pathway to engineering skin devices	5
Enhanced non-viral gene delivery via calcium phosphate/DNA co-precipitates with low-voltage pulse electroporation in NK-92 cells for immunocellular therapy	5
Long-acting acid-sensitive ketal-linked dexamethasone microcrystals for treating experimental autoimmune uveitis	5
Decoding force-transmission linkages for therapeutic targeting and engineering	5
Recent advancements in polymer science for retinal diseases: New frontiers in drug delivery systems	5
Programmed wound healing in aged skin may be enhanced by mesenchymal cell loaded gene-activated scaffolds	4
Parallel on-chip micropipettes enabling quantitative multiplexed characterization of vesicle mechanics and cell aggregates rheology	4
Survivin modulates stiffness-induced vascular smooth muscle cell motility	4
4D Light-sheet imaging and interactive analysis of cardiac contractility in zebrafish larvae	4
Asymmetrical positioning of cell organelles reflects the cell chirality of mouse myoblast cells	4
Oscillatory shear stress-induced downregulation of TET1s injures vascular endothelial planar cell polarity by suppression of actin polymerization	4
Possibilities in bioelectronics: Super humans or science fiction?	4
Use of mesoporous polydopamine nanoparticles as a stable drug-release system alleviates inflammation in knee osteoarthritis	4
Recent progress in electrospun nanomaterials for wearables	4

Finger joint angle and gesture estimation under natural conditions with a soft printed electrode array	4
Multicompartment duct platform to study epithelial–endothelial crosstalk associated with lung adenocarcinoma	4
Subject-specific multivariate modeling for regenerative rehabilitation of bone healing	4
Different contractility modes control cell escape from multicellular spheroids and tumor explants	4
Mechanotransduction for therapeutic approaches: Cellular aging and rejuvenation	4
Osteogenically committed hUCMSCs-derived exosomes promote the recovery of critical-sized bone defects with enhanced osteogenic properties	4
Review of robotic systems for thoracoabdominal puncture interventional surgery	4
Polarized macrophages modulate cardiac structure and contractility under hypoxia in novel immuno-heart on a chip	4
In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein	4
Heterojunction semiconductor nanocatalysts as cancer theranostics	3
Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder	3
Memory in repetitive protein–protein interaction series	3
Assessing human scalp and brain blood flow sensitivities via superficial temporal artery occlusion using speckle contrast optical spectroscopy	3
Engineered tissue geometry and Plakophilin-2 regulate electrophysiology of human iPSC-derived cardiomyocytes	3
Retraction: “Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow” [APL Bioeng. 6, 046104 (2022)]	3
Testing mixing rules for structural and dynamical quantities in multi-component crowded protein solutions	3
Gut-on-a-chip models for dissecting the gut microbiology and physiology	3
Biophysical and biochemical aspects of immune cell–tumor microenvironment interactions	3
Electrodynamic interaction between tumor treating fields and microtubule electrophysiological activities	3
Magnetic force-based cell manipulation for in vitro tissue engineering	3
Insights into the mechanobiology of cancer metastasis via microfluidic technologies	3
Frequency and duration of sensory flicker control transcriptional profiles in 5xFAD mice	3
Photothermal therapy using graphene quantum dots	3
Interstitial fluid flow in an engineered human lymph node stroma model modulates T cell egress and stromal change	3
Epigenetic dynamics in meniscus cell migration and its zonal dependency in response to inflammatory conditions	3
High cell throughput, programmable fixation reveals the RNA and protein co-regulation with spatially resolved NFκB pseudo-signaling	3
Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler	3
Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis	3
Biophysical perspectives to understanding cancer-associated fibroblasts	3
Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing	3
Functional biomaterials	3
Advancing hyperspectral imaging and machine learning tools toward clinical adoption in tissue diagnostics: A comprehensive review	3
Multi-actuator light-controlled biological robots	3
Nuclear lamins: Structure and function in mechanobiology	3
Engineering interfacial tissues: The myotendinous junction	3
Skin wound healing improvement in diabetic mice through FTIR microspectroscopy after implanting pluripotent stem cells	3
Glutathione-sensitive nanoparticles enhance the combined therapeutic effect of checkpoint kinase 1 inhibitor and cisplatin in prostate cancer	3