APL Bioengineering

Article	Citations
Synergy between photonics and biological approaches—A review of combination therapies for cancer theranostics	104
Black phosphorus-enhanced injectable hydrogel for infected soft tissue healing	87
Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome	47
Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration	39
Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus	38
Scheduled dosage regimen by irreversible electroporation of loaded erythrocytes for cancer treatment	36
Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair	35
Aqueous electrolyte-gated solution-processed metal oxide transistors for direct cellular interfaces	35
A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces	34
Unpleasant odors compared to pleasant ones cause higher cortical activations detectable by fNIRS and observable mostly in females	33
Computational modeling of the physical features that influence breast cancer invasion into adipose tissue	30
Fibroblast senescence-associated extracellular matrix promotes heterogeneous lung niche	30
A novel portable in situ printer for hydrogel multi-structure molding and cell printing	29
Exploring the translational impact of type 1 diabetes on cerebral neurovascular function through ECoG-LSCI	29
Enhancing upper limb motor recovery prediction after acute stroke using EEG and subacute data	27
3D bioprinted human iPSC-derived neural progenitor cells as a novel platform for studying neurogenic niche	27
Electrophysiological features of cortical 3D networks are deeply modulated by scaffold properties	27
A fully automated deep learning approach for coronary artery segmentation and comprehensive characterization	26
Geometrically engineered organoid units and their assembly for pre-construction of organ structures	26
Machine learning-informed predictions of nanoparticle mobility and fate in the mucus barrier	25
GelMA micropattern enhances cardiomyocyte organization, maturation, and contraction via contact guidance	25
The role of biomechanical factors in models of intervertebral disc degeneration across multiple length scales	24
Learning discrete structures for cancer radiomics	24
Non-contact radiofrequency stimulation to the olfactory nerve of human subjects	23
Degradation-aware neural imputation: Advancing decoding stability in brain machine interfaces	23

Formononetin suppresses osteosarcoma by targeting MYO1B and remodeling the tumor immune microenvironment	22
Mechanism study on the influences of buffer osmotic pressure on microfluidic chip-based cell electrofusion	21
Orthopedic meta-implants	21
Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges	20
A comprehensive review of graphene-based biosensors: Fabrication, applications, characterization and future perspectives—A review	19
Model discovery approach enables noninvasive measurement of intra-tumoral fluid transport in dynamic MRI	19
Immunogenic cell death-related cancer-associated fibroblast clusters and prognostic risk model in cervical cancer	19
Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes	18
Fluorescence spectroscopy as a novel tool in hematological diagnostics	18
Advancements in textile techniques for cardiovascular tissue replacement and repair	18
Tissue regenerative medicine: Clinical advances, challenges, and opportunities	18
M/EEG source localization for both subcortical and cortical sources using a convolutional neural network with a realistic head conductivity model	18
Multi-omics mapping identifies CYBA-mediated mitochondrial dysfunction driving macrophage polarization and ferroptosis via Nrf2 pathway in atherosclerosis	17
Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels	17
Regulation of airway remodeling in asthma: The synergistic effects of nanotechnology and Hippo pathway activation	17
Advanced biomaterial strategies for overcoming age-associated wound healing impairments	17
Terahertz in vivo imaging of human skin: Toward detection of abnormal skin pathologies	17
In vivo label-free tissue histology through a microstructured imaging window	16
Injectable photosensitive bone cement enhancing angiogenesis and osteogenic differentiation for the treatment of bone nonunion	16
Digital light processing of hydrogel molds to guide cell mechanosensing and the fabrication of meniscal tissue constructs	15
Altered blood flow due to larger aortic diameters in patients with transcatheter heart valve thrombosis	15
Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects	15
The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment	15
CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays	15
TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis	15
Publisher's Note: “Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler” [APL Bioeng. 6, 036102 (2022)]	15
Long-term effect of sodium selenite on the integrity and permeability of on-chip microvasculature	15
Research progress in flap temperature monitoring technologies and applications after transplantation	15
A review: Blood pressure monitoring based on PPG and circadian rhythm	15
Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system	15
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing	14
Fluid flow to mimic organ function in 3D in vitro models	14
Single-pericyte nanomechanics measured by contraction cytometry	14
Investigations on artificially extending the spectral range of natural vision	14
Mechanical cues orchestrate monocyte behavior in immune regulation and disease	14
Quercetin targets the Ccl4–Ccr5 axis to relieve neuropathic pain after spinal cord injury	14
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology	13
Biosensors integrated within wearable devices for monitoring chronic wound status	13
High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array	13
Mechanobiology of the cell nucleus	13
Hypoxia-induced drug-resistance bias 3D cancer spheroid drug screens	13
Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo	13
Collagen density regulates tip–stalk cell rearrangement during angiogenesis via cellular bioenergetics	13
Hemodynamics of thrombus formation in intracranial aneurysms: An in silico observational study	13
Magnetic self-assembly of 3D multicellular microscaffolds: A biomimetic brain tumor-on-a-chip for drug delivery and selectivity testing	12
Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells	12
A high throughput cell stretch device for investigating mechanobiology in vitro	12
PEDOT:PSS-coated platinum electrodes for neural stimulation	12
Epigenetic regulation and mechanobiological adaptation in tenocytes during maturation	12
Modeling nitric oxide diffusion and plasticity modulation in cerebellar learning	12

Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins	12
Photoplethysmography-based HRV analysis and machine learning for real-time stress quantification in mental health applications	12
Rapid flowing cells localization enabled by spatiotemporal manipulation of their holographic patterns	11
All-in-one properties of an anticancer-covered airway stent for the prevention of malignant central airway obstruction	11
Mutual antagonism between CD44 and integrins in glioblastoma cell traction and migration	11
Stem cell mechanoadaptation. II. Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling	11
Publisher's Note: “Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility” [APL Bioeng. 7	11
Engineered matrix microenvironments reveal the heterogeneity of liver sinusoidal endothelial cell phenotypic responses	11
Engineering approaches for understanding mechanical memory in cancer metastasis	11
Low-intensity pulsed ultrasound irradiation ameliorates gut inflammation and neuroinflammation in mice with DSS-induced colitis	11
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells	11
Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation	11
Surface electromyography using dry polymeric electrodes	11
Mechanomedicine: Translating mechanical forces into therapeutic strategies	11
Imaging of the vascular distribution of the outer ear using optical coherence tomography angiography for highly accurate positioning of a hearable sensor	11
3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells	11
Burst sine wave electroporation (B-SWE) for expansive blood–brain barrier disruption and controlled non-thermal tissue ablation for neurological disease	11
Cerebellar contribution to multisensory integration: A computational modeling exploration	11
Metronomic photodynamic therapy for deep organ cancer by implantable wireless OLEDs	10
Investigating cartilage-related diseases by polarization-resolved second harmonic generation (P-SHG) imaging	10
Fluid shear stress induced-endothelial phenotypic transition contributes to cerebral ischemia–reperfusion injury and repair	10
Drug/gene delivery and theranostics	10
Stiffness-mediated paracrine signaling enhances induction of EMT in oral squamous cell carcinoma	10
The mechanobiology of fibroblast activation in disease	10
GelMA-glycol chitosan hydrogels for cartilage regeneration: The role of uniaxial mechanical stimulation in enhancing mechanical, adhesive, and biochemical properties	10
Silk fibroin promotes H3K9me3 expression and chromatin reorganization to regulate endothelial cell proliferation	10
Generation of direct current electrical fields as regenerative therapy for spinal cord injury: A review	10
Mapping the miRNA landscape of primitive macrophage extracellular vesicles highlights their pro-vasculogenic effects in engineered human cardiac tissue	9
Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow	9
A multi-scale numerical approach to study monoclonal antibodies in solution	9
Application of instant assembly of collagen to bioprint cardiac tissues	9
Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model	9
Human gut epithelium features recapitulated in MINERVA 2.0 millifluidic organ-on-a-chip device	9
Guest Editorial: Structure and mechanics of biofluids, biomaterials, and biologics	9
Publisher's Note: “Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design” [APL Bioeng. 7	9
Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids	9
Mechanobiological engineering strategies for organoid culture	9
Structure–function relationships for squid skin-inspired wearable thermoregulatory materials	9
Region-dependent mechanical parameters in simulating cerebral atrophy	8
Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design	8
Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility	8
Long-term day-by-day tracking of microvascular networks sprouting in fibrin gels: From detailed morphological analyses to general growth rules	8
Studying the roles of salt ions in the pore initiation and closure stages in the biomembrane electroporation	8
Multifunctional scaffolds for biomedical applications: Crafting versatile solutions with polycaprolactone enriched by graphene oxide	8
Optimization frameworks for bespoke sensory encoding in neuroprosthetics	8
IgG and IgM differentiation in a particle-based agglutination assay by control over antigen surface density	8
Mechanoimmunology: Are inflammatory epigenetic states of macrophages tuned by biophysical factors?	8
A modular and reconfigurable microfluidic device for culturing spheroids under continuous perfusion	7
Editorial Series conclusion and journal outlook	7
User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium	7
Cardiac mechanotransduction from development to disease	7
A fully implantable sensorized artificial urinary bladder to restore continence and fullness monitoring	7
Skin-on-chip: Quo vadis?	7
Publisher's Note: “Magnetic force-based cell manipulation for in vitro tissue engineering” [APL Bioeng. 7 , 031504 (2023)]	7
Erratum: “Credibility assessment of patient-specific modeling in transcatheter aortic valve implantation. I. A population-based validation of patient-specific modeling” [APL Bioeng.	7
Apoptosis-associated genetic mechanisms in the transition from rheumatoid arthritis to osteoporosis: A bioinformatics and functional analysis approach	7
Investigating the reliability of the evoked response in human iPSCs-derived neuronal networks coupled to micro-electrode arrays	7
Mesenchymal stem cell membrane-coated kaempferol biomimetic nanoformulation for the treatment of atherosclerosis	7
3D confinement alters smooth muscle cell responses to chemical and mechanical cues	7
Gold nanorods with iron oxide dual-modal bioprobes in SERS-MRI enable accurate programmed cell death ligand-1 expression detection in triple-negative breast cancer	7
Highly stretchable and sensitive silicone composites with positive piezoconductivity using nickel powder and ionic liquid	7
Biobased adhesive hydrogels for wound management and tissue repair: From materials to advanced applications	7
Applying physical principles to cancer research	6
Hydrodynamic efficient cell capture and pairing method on microfluidic cell electrofusion chip	6
Long-acting acid-sensitive ketal-linked dexamethasone microcrystals for treating experimental autoimmune uveitis	6
Force-sensing mobile microrobotic grippers for gentle and precise bioassembly of cell spheroids	6
The effect of chronic kidney disease on tissue formation of in situ tissue-engineered vascular grafts	6
Evaluation of screw pull-out from plate fixation of en bloc distal radius resection with ulnar reconstruction: Finite element analysis and comparison with experiments on Thiel cadavers	6
Decoding force-transmission linkages for therapeutic targeting and engineering	6
Recent advancements in polymer science for retinal diseases: New frontiers in drug delivery systems	6
Parallel on-chip micropipettes enabling quantitative multiplexed characterization of vesicle mechanics and cell aggregates rheology	6
Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts	6
AI-aided holographic flow cytometry for label-free identification of ovarian cancer cells in the presence of unbalanced datasets	6
Peptide coacervates as intracellular delivery vehicles for synergistic cancer photothermal- and chemo-therapies	6
Enhanced non-viral gene delivery via calcium phosphate/DNA co-precipitates with low-voltage pulse electroporation in NK-92 cells for immunocellular therapy	5
Recent progress in electrospun nanomaterials for wearables	5
Review of robotic systems for thoracoabdominal puncture interventional surgery	5
In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein	5
Retraction: “Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow” [APL Bioeng. 6, 046104 (2022)]	5
Programmed wound healing in aged skin may be enhanced by mesenchymal cell loaded gene-activated scaffolds	5

Osteogenically committed hUCMSCs-derived exosomes promote the recovery of critical-sized bone defects with enhanced osteogenic properties	5
Elastocapillary effects determine early matrix deformation by glioblastoma cell spheroids	5
Survivin modulates stiffness-induced vascular smooth muscle cell motility	5
Different contractility modes control cell escape from multicellular spheroids and tumor explants	5
ChatGPT in precision medicine	5
Polarized macrophages modulate cardiac structure and contractility under hypoxia in novel immuno-heart on a chip	5
Prediction of chronic obstructive pulmonary disease based on multimodal data and deep learning	5
Post-stroke spontaneous motor recovery in mice can be predicted from acute-phase local field potential using machine learning	5
Mechanotransduction for therapeutic approaches: Cellular aging and rejuvenation	5
Finger joint angle and gesture estimation under natural conditions with a soft printed electrode array	5
Asymmetrical positioning of cell organelles reflects the cell chirality of mouse myoblast cells	5
Multicompartment duct platform to study epithelial–endothelial crosstalk associated with lung adenocarcinoma	5
Magnetic force-based cell manipulation for in vitro tissue engineering	4
High cell throughput, programmable fixation reveals the RNA and protein co-regulation with spatially resolved NFκB pseudo-signaling	4
Memory in repetitive protein–protein interaction series	4
Insights into the mechanobiology of cancer metastasis via microfluidic technologies	4
Machine learning-enabled detection of electrophysiological signatures in iPSC-derived models of schizophrenia and bipolar disorder	4
Frequency and duration of sensory flicker control transcriptional profiles in 5xFAD mice	4
Assessing human scalp and brain blood flow sensitivities via superficial temporal artery occlusion using speckle contrast optical spectroscopy	4
Testing mixing rules for structural and dynamical quantities in multi-component crowded protein solutions	4
Engineering interfacial tissues: The myotendinous junction	4
Heterojunction semiconductor nanocatalysts as cancer theranostics	4
The viscoelasticity of high concentration monoclonal antibodies using particle tracking microrheology	4
Gut-on-a-chip models for dissecting the gut microbiology and physiology	4
Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis	4
Biophysical perspectives to understanding cancer-associated fibroblasts	4
Interstitial fluid flow in an engineered human lymph node stroma model modulates T cell egress and stromal change	4
Subject-specific multivariate modeling for regenerative rehabilitation of bone healing	4
4D Light-sheet imaging and interactive analysis of cardiac contractility in zebrafish larvae	4
Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler	4
Multi-actuator light-controlled biological robots	4
Mechanomemory after short episodes of intermittent stresses induces YAP translocation via increasing F-actin	4
Skin wound healing improvement in diabetic mice through FTIR microspectroscopy after implanting pluripotent stem cells	4
On-chip fabrication of tailored 3D hydrogel scaffolds to model cancer cell invasion and interaction with endothelial cells	4
Biophysical and biochemical aspects of immune cell–tumor microenvironment interactions	4
Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing	4
Engineered tissue geometry and Plakophilin-2 regulate electrophysiology of human iPSC-derived cardiomyocytes	4
Electrodynamic interaction between tumor treating fields and microtubule electrophysiological activities	4
Photothermal therapy using graphene quantum dots	4
Oscillatory shear stress-induced downregulation of TET1s injures vascular endothelial planar cell polarity by suppression of actin polymerization	4
Advancing hyperspectral imaging and machine learning tools toward clinical adoption in tissue diagnostics: A comprehensive review	4
Epigenetic dynamics in meniscus cell migration and its zonal dependency in response to inflammatory conditions	4
Glutathione-sensitive nanoparticles enhance the combined therapeutic effect of checkpoint kinase 1 inhibitor and cisplatin in prostate cancer	4
Low-intensity pulsed ultrasound alleviates periodontitis in mice with T2DM through Nrf2 pathway	4