OOIR: Observatory of International Research

Papers

(The TQCC of APL Bioengineering is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Synergy between photonics and biological approaches—A review of combination therapies for cancer theranostics	109
Black phosphorus-enhanced injectable hydrogel for infected soft tissue healing	91
Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome	48
Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus	41
Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration	39
A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces	37
Aqueous electrolyte-gated solution-processed metal oxide transistors for direct cellular interfaces	37
Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair	37
Enhancing upper limb motor recovery prediction after acute stroke using EEG and subacute data	35
Scheduled dosage regimen by irreversible electroporation of loaded erythrocytes for cancer treatment	35
3D bioprinted human iPSC-derived neural progenitor cells as a novel platform for studying neurogenic niche	32
GelMA micropattern enhances cardiomyocyte organization, maturation, and contraction via contact guidance	31
Computational modeling of the physical features that influence breast cancer invasion into adipose tissue	31
Machine learning-informed predictions of nanoparticle mobility and fate in the mucus barrier	30
Exploring the translational impact of type 1 diabetes on cerebral neurovascular function through ECoG-LSCI	28
Geometrically engineered organoid units and their assembly for pre-construction of organ structures	27
Electrophysiological features of cortical 3D networks are deeply modulated by scaffold properties	27
A novel portable in situ printer for hydrogel multi-structure molding and cell printing	27
Unpleasant odors compared to pleasant ones cause higher cortical activations detectable by fNIRS and observable mostly in females	27
Learning discrete structures for cancer radiomics	26
A fully automated deep learning approach for coronary artery segmentation and comprehensive characterization	26
Fibroblast senescence-associated extracellular matrix promotes heterogeneous lung niche	26
Formononetin suppresses osteosarcoma by targeting MYO1B and remodeling the tumor immune microenvironment	25
Orthopedic meta-implants	24
Model discovery approach enables noninvasive measurement of intra-tumoral fluid transport in dynamic MRI	23

Non-contact radiofrequency stimulation to the olfactory nerve of human subjects	23
Mechanism study on the influences of buffer osmotic pressure on microfluidic chip-based cell electrofusion	23
The role of biomechanical factors in models of intervertebral disc degeneration across multiple length scales	22
Degradation-aware neural imputation: Advancing decoding stability in brain machine interfaces	22
Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges	21
A comprehensive review of graphene-based biosensors: Fabrication, applications, characterization and future perspectives—A review	20
Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes	19
Immunogenic cell death-related cancer-associated fibroblast clusters and prognostic risk model in cervical cancer	19
Advancements in textile techniques for cardiovascular tissue replacement and repair	19
Fluorescence spectroscopy as a novel tool in hematological diagnostics	18
Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels	18
Terahertz in vivo imaging of human skin: Toward detection of abnormal skin pathologies	18
M/EEG source localization for both subcortical and cortical sources using a convolutional neural network with a realistic head conductivity model	18
Tissue regenerative medicine: Clinical advances, challenges, and opportunities	18
Regulation of airway remodeling in asthma: The synergistic effects of nanotechnology and Hippo pathway activation	18
Digital light processing of hydrogel molds to guide cell mechanosensing and the fabrication of meniscal tissue constructs	17
In vivo label-free tissue histology through a microstructured imaging window	17
CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays	17
Injectable photosensitive bone cement enhancing angiogenesis and osteogenic differentiation for the treatment of bone nonunion	17
Research progress in flap temperature monitoring technologies and applications after transplantation	17
Altered blood flow due to larger aortic diameters in patients with transcatheter heart valve thrombosis	16
TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis	16
Multi-omics mapping identifies CYBA-mediated mitochondrial dysfunction driving macrophage polarization and ferroptosis via Nrf2 pathway in atherosclerosis	16
Advanced biomaterial strategies for overcoming age-associated wound healing impairments	16
Investigations on artificially extending the spectral range of natural vision	15
Long-term effect of sodium selenite on the integrity and permeability of on-chip microvasculature	15
Mechanical cues orchestrate monocyte behavior in immune regulation and disease	15
Quercetin targets the Ccl4–Ccr5 axis to relieve neuropathic pain after spinal cord injury	15
Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system	15
The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment	15
Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects	15
A review: Blood pressure monitoring based on PPG and circadian rhythm	15
Publisher's Note: “Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler” [APL Bioeng. 6, 036102 (2022)]	15
Fluid flow to mimic organ function in 3D in vitro models	15
Collagen density regulates tip–stalk cell rearrangement during angiogenesis via cellular bioenergetics	14
Biosensors integrated within wearable devices for monitoring chronic wound status	14
Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells	14
Single-pericyte nanomechanics measured by contraction cytometry	14
Hypoxia-induced drug-resistance bias 3D cancer spheroid drug screens	14
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology	14
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins	14
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing	14
Mechanobiology of the cell nucleus	14
Magnetic self-assembly of 3D multicellular microscaffolds: A biomimetic brain tumor-on-a-chip for drug delivery and selectivity testing	14
Hemodynamics of thrombus formation in intracranial aneurysms: An in silico observational study	14
A high throughput cell stretch device for investigating mechanobiology in vitro	13
High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array	13
PEDOT:PSS-coated platinum electrodes for neural stimulation	12
Photoplethysmography-based HRV analysis and machine learning for real-time stress quantification in mental health applications	12
Engineered matrix microenvironments reveal the heterogeneity of liver sinusoidal endothelial cell phenotypic responses	12

Epigenetic regulation and mechanobiological adaptation in tenocytes during maturation	12
Modeling nitric oxide diffusion and plasticity modulation in cerebellar learning	12
Publisher's Note: “Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility” [APL Bioeng. 7	12
Rapid flowing cells localization enabled by spatiotemporal manipulation of their holographic patterns	12
Engineering approaches for understanding mechanical memory in cancer metastasis	12
Cerebellar contribution to multisensory integration: A computational modeling exploration	12
Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation	12
Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo	12
Surface electromyography using dry polymeric electrodes	12
Burst sine wave electroporation (B-SWE) for expansive blood–brain barrier disruption and controlled non-thermal tissue ablation for neurological disease	12
Imaging of the vascular distribution of the outer ear using optical coherence tomography angiography for highly accurate positioning of a hearable sensor	11
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells	11
Drug/gene delivery and theranostics	11
Fluid shear stress induced-endothelial phenotypic transition contributes to cerebral ischemia–reperfusion injury and repair	11
Stem cell mechanoadaptation. II. Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling	11
The mechanobiology of fibroblast activation in disease	11
Mutual antagonism between CD44 and integrins in glioblastoma cell traction and migration	11
3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells	11
All-in-one properties of an anticancer-covered airway stent for the prevention of malignant central airway obstruction	11
Low-intensity pulsed ultrasound irradiation ameliorates gut inflammation and neuroinflammation in mice with DSS-induced colitis	11
Stiffness-mediated paracrine signaling enhances induction of EMT in oral squamous cell carcinoma	11
Mechanomedicine: Translating mechanical forces into therapeutic strategies	11
Mechanobiological engineering strategies for organoid culture	11
GelMA-glycol chitosan hydrogels for cartilage regeneration: The role of uniaxial mechanical stimulation in enhancing mechanical, adhesive, and biochemical properties	11