OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Metabolism is 70. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Run to survive—how preoperative exercise could prevent major surgical complications	783
Glycolysis modulates efferocytosis in a noncanonical manner	451
The cell cycle loops UTP around CAD	393
Publisher Correction: Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel–Lindau syndrome	310
Phagocytosis in the retina promotes local insulin production in the eye	299
Acarbose enhances the efficacy of immunotherapy against solid tumours by modulating the gut microbiota	281
Author Correction: Exercise hormone irisin is a critical regulator of cognitive function	269
Regulation of urea cycle by reversible high-stoichiometry lysine succinylation	268
An ATP-sensitive phosphoketolase regulates carbon fixation in cyanobacteria	219
The rs1421085 variant within FTO promotes brown fat thermogenesis	194
Total parenteral nutrition impairs glucose metabolism by modifying the gut microbiome	193
What is the most appropriate covariate in ANCOVA when analysing metabolic rate?	189
Improved polyketide production in C. glutamicum by preventing propionate-induced growth inhibition	185
Allosteric regulation of CAD modulates de novo pyrimidine synthesis during the cell cycle	179
Targeted erasure of DNA methylation by TET3 drives adipogenic reprogramming and differentiation	169
Incretin-based therapeutics for the treatment of neurodegenerative diseases	155
Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis	139
GLP-1 physiology in obesity and development of incretin-based drugs for chronic weight management	138
Recommendations for mitochondria transfer and transplantation nomenclature and characterization	136
Cotadutide promotes glycogenolysis in people with overweight or obesity diagnosed with type 2 diabetes	127
The cyclic metabolic switching theory of intermittent fasting	125
Microbial metabolite delta-valerobetaine is a diet-dependent obesogen	125
A conserved role for PCYT2-regulated lipid biosynthesis in muscle health and ageing	117
A BCAA–haem axis regulates brown fat function	115
Skeletal muscle, not adipose tissue, mediates cold-induced metabolic benefits	113

Hot news about temperature and lifespan	113
Exercise activates AMPK in mouse and human pancreatic islets to decrease senescence	109
Hypermetabolism and energetic constraints in mitochondrial disorders	108
Best practices in collecting and reporting continuous glucose monitoring data in research settings	107
The sphingosine-1-phosphate receptor 1 mediates the atheroprotective effect of eicosapentaenoic acid	106
Hypothalamic GABRA5-positive neurons control obesity via astrocytic GABA	104
Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress	104
TKT deficiency puts Tregs to rest	103
The thyroid gland under Notch control	101
Fuelling the fire: de novo lipogenesis primes thermogenesis	101
Paracrine signalling by pancreatic δ cells determines the glycaemic set point in mice	100
Gut bacteria thwart the blood sugar-lowering effect of acarbose	100
Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice	99
Spatial hepatocyte plasticity of gluconeogenesis during the metabolic transitions between fed, fasted and starvation states	98
Spatial metabolomics: from a niche field towards a driver of innovation	97
Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity	95
Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions	95
GIPR-Ab/GLP-1 peptide–antibody conjugate requires brain GIPR and GLP-1R for additive weight loss in obese mice	93
NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury	90
The antitumour effects of caloric restriction are mediated by the gut microbiome	89
Illuminating the ‘healthy obese’ phenotype	89
Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance	89
5-IP7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis	88
Methionine and H2S alter cancer–immune dialogue	87
Mitochondrial RNA stimulates beige adipocyte development in young mice	87
Proline fuels ILC3s to maintain gut health	87
Pathogenic role of acyl coenzyme A binding protein (ACBP) in Cushing’s syndrome	85
Rapid modulation of gut microbiota composition by hypothalamic circuits in mice	84
Gases define redox signalling: NO, H2S, O2 … and cyanide	84
Astrocytic BDNF signaling within the ventromedial hypothalamus regulates energy homeostasis	83
Umami-induced obesity and metabolic syndrome is mediated by nucleotide degradation and uric acid generation	83
Abnormal exocrine–endocrine cell cross-talk promotes β-cell dysfunction and loss in MODY8	82
Querying stool for dietary information	81
Why a good lab website matters	80
A systematic mutational framework for studying oxidative phosphorylation-related proteins	78
Hypometabolism with the speed of ultrasound	77
A RalA between high-fat diet and mitochondrial shape	76
Beyond Warburg: LDHA activates RAC for tumour growth	76
Intestinal TM6SF2 protects against metabolic dysfunction-associated steatohepatitis through the gut–liver axis	74
From NAFLD to MASLD: implications of the new nomenclature for preclinical and clinical research	73
A century of the Warburg effect	73
HK1 from hepatic stellate cell–derived extracellular vesicles promotes progression of hepatocellular carcinoma	72
Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation	71
A researcher’s guide to preclinical mouse NASH models	71
Neurometabolism in focus	70
Cancer metabolite blunts immunity	70