JOR Spine

Article	Citations
	104
Injection Volume Is a Better Predictor of Stiffness Restoration Than Injection Force in an In Vitro Study of Nucleus Augmentation of the Intervertebral Disc	95
Exploring the Biopsychosocial Impact of Chronic Low Back Pain in Workers Through Artificial Intelligence‐Driven Phenotyping	56
Feasibility of Physical Exam and Performance‐Based Tests in Individuals With Chronic Low Back Pain: A Descriptive Study	44
Clinical efficacy and biomechanical analysis of a novel hollow pedicle screw combined with kyphoplasty for the treatment of Kümmell disease	43
The effects of extracellular matrix‐degrading enzymes polymorphisms on intervertebral disc degeneration	43
Neoepitope fragments as biomarkers for different phenotypes of intervertebral disc degeneration	39
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Comparison of four in vitro test methods to assess nucleus pulposus replacement device expulsion risk	25
The efficacy and safety of oral antibiotic treatment in patients with chronic low back pain and Modic changes: A systematic review and meta‐analysis	24
Bone morphogenetic proteins, DNA methylation, and gut microbiota interaction in lumbar disc degeneration: A multi‐omics Mendelian randomization study	21
Tracing the disc: The novel qualitative morphometric MRI based disc degeneration classification system	20
M1 macrophage‐derived oncostatin M induces osteogenic differentiation of ligamentum flavum cells through the JAK2/STAT3 pathway	20
Issue Information	19
Can axial loading restore in vivo disc geometry, opening pressure, and T2 relaxation time?	19
Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy	19
Repetitive strikes loading organ culture model to investigate the biological and biomechanical responses of the intervertebral disc	18
Exploring the therapeutic potential of puerarin on intervertebral disc degeneration by regulating apoptosis of nucleus pulposus cells	18
Effect of cigarette smoke exposure and cessation on regional diffusion properties in rat intervertebral discs	18
Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants	17
TNFα Receptor 1 and Not Receptor 2 Affect Annulus Fibrosus and Nucleus Pulposus Response to Cytokine Challenge in a Rat Model	17
Paraspinal muscles in individuals undergoing surgery for lumbar spine pathology lack a myogenic response to an acute bout of resistance exercise	17
Beyond the Curve: The Muscle‐Specific Asymmetries of Adolescent Idiopathic Scoliosis	16
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Analysis of Nicotine Toxicity and Mechanisms of Senescence in Nucleus Pulposus Cells Using Network Toxicology and Molecular Docking Technique	15

Evaluation of instrumentation and pedicle screw design for posterior lumbar fixation: A pre‐clinical in vivo/ex vivo ovine model	15
Recommendations for intervertebral disc notochordal cell investigation: From isolation to characterization	15
Advanced Glycation End Products Induce Caudal Disc Degeneration in Ovariectomized Female Rats	14
Rapamycin mitigates inflammation‐mediated disc matrix homeostatic imbalance by inhibiting mTORC1 and inducing autophagy through Akt activation	13
The proteomic landscape of extracellular vesicles derived from human intervertebral disc cells	13
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Constitutive and conditional gene knockout mice for the study of intervertebral disc degeneration: Current status, decision considerations, and future possibilities	12
Understanding the Physiological Behavior of Disc Cells in an In Vitro Imitation of the Healthy and Degenerated Disc Niche	12
Three‐dimensional ultrasonography could be a potential non‐ionizing tool to evaluate vertebral rotation of subjects with adolescent idiopathic scoliosis	12
Deep learning‐based detection and classification of lumbar disc herniation on magnetic resonance images	12
How to improve the mechanical safety of a novel spinal implant while saving costs and time	11
Static study and numerical simulation of the influence of cement distribution in the upper and lower adjacent vertebrae on sandwich vertebrae in osteoporotic patients: Finite element analysis	11
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Ovine model of congenital chest wall and spine deformity: From birth to 3 months follow‐up	11
Issue Information	11
Issue Information	11
Single‐Cell Analysis Integrated With Machine Learning Elucidates the Mechanisms of Nucleus Pulposus Cells Apoptosis in Intervertebral Disc Degeneration and Therapeutic Interventions	11
Nonviral overexpression of Scleraxis or Mohawk drives reprogramming of degenerate human annulus fibrosus cells from a diseased to a healthy phenotype	10
Biomedical applications of silk and its role for intervertebral disc repair	10
Evaluation of Lumbar Intervertebral Disc and Facet Joint Degeneration Using Histogram Analysis of T2 and T2	9
The Cross‐Sectional Areas and Anterior–Posterior Balance of the Cervical Paraspinal Muscles in Dropped Head Syndrome and Cervical Spondylotic Myelopathy: A Propensity Score‐Matched Analysis	9
Dynamic loading leads to increased metabolic activity and spatial redistribution of viable cell density in nucleus pulposus tissue	9
Lumbopelvic Kinematics During Functional Tasks in a Chronic Low Back Pain Observational Cohort	9
Deep learning‐based structure segmentation and intramuscular fat annotation on lumbar magnetic resonance imaging	9
Macrophage Changes and High‐Throughput Sequencing in Aging Mouse Intervertebral Disks	9
Molecular Subtypes and Immune Microenvironment Characterization of the Annulus Fibrosus in Intervertebral Disc Degeneration: Insights From Translation Factor‐Related Gene Analysis	9
Clinical implications of linking microstructure, spatial biochemical, spatial biomechanical, and radiological features in ligamentum flavum degeneration	9
Correction to “Development and validation of deep learning models for identifying the brand of pedicle screws on plain spine radiographs”	9
Why clinical trials in disc regeneration strive to achieve completion: Insights from publication status and funding sources	9
The Helical Compliance Vector: Utility for Quantifying Spinal Mechanics	8
Phase 1 evaluation of an elastomeric nucleus pulposus device as an option to augment disc at microdiscectomy: Experimental results from biomechanical and biocompatibility testing and first in human	8
FAM172A supervises ER (endoplasmic reticulum) stress‐triggered autophagy in the epidural fibrosis process	8
Preclinical in vivo animal models of intervertebral disc degeneration. Part 1: A systematic review	8
Associations between femoral 3D curvature and sagittal imbalance of spine	8
MRI‐based degeneration grades for lumbar facet joints do not correlate with cartilage mechanics	8
Silibinin promotes healing in spinal cord injury through anti‐ferroptotic mechanisms	8
Ruxolitinib Delays Nucleus Pulposus Cell Senescence in Rat Intervertebral Discs	8
Diurnal Asymmetric Loading Modulates Cell Phenotype in Intervertebral Disc	8
The effect of fatty infiltration, revision surgery, and sex on lumbar multifidus passive mechanical properties	8
Range of Motion and Neutral Zone of All Human Spinal Motion Segments: A Data Collection of 30 Years of In Vitro Experiments Performed Under Standardized Testing Conditions	8
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Biomechanical evaluation of a novel biomimetic artificial intervertebral disc in canine cervical cadaveric spines	7
Physiological and Anthropometric Factors Associated With Spine Loading Estimates From Imaging‐Based Subject‐Specific Musculoskeletal Models	7
Single‐Side Iatrogenic Pedicle Injury May Trigger an Increased Risk of Contralateral Screw Loosening: An In Silico Study	7
Enhancing Clinical Insights: New Radiographic Grading for Lumbar Facet Joint Degeneration, A Reliability Study	7
Finite element modeling to predict the influence of anatomic variation and implant placement on performance of biological intervertebral disc implants	7
Identifying critical modules and biomarkers of intervertebral disc degeneration by using weighted gene co‐expression network	7
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The non‐causative role of abnormal serum uric acid in intervertebral disc degeneration: A Mendelian randomization study	7
Analysis of the value of potential biomarker S100‐A8 protein in the diagnosis and pathogenesis of spinal tuberculosis	7

Axial hypersensitivity is associated with aberrant nerve sprouting in a novel model of disc degeneration in female Sprague Dawley rats	7
Exploring the Causal Relationship Between the Plasma Levels of MMP1 (Matrix Metalloproteinase‐1), MMP3, MMP7, MMP10, and MMP12 and Intervertebral	7
Plasma Pro‐ and Anti‐Inflammatory Cytokines in an Observational Chronic Low Back Pain Cohort	7
Issue Information	6
Transient Receptor Potential Vanilloid 4 Knockdown Decreases Extracellular Matrix Synthesis via Autophagy Suppression in the Rat Intervertebral Disc	6
An in vivo model of ligamentum flavum hypertrophy from early‐stage inflammation to fibrosis	6
Evidence for a Causal Association Between Human Cytomegalovirus Infection and Chronic Back Pain: A One‐Sample Mendelian Randomization Study	6
Focal osteoporosis defect is associated with vertebral compression fracture prevalence in a bone mineral density‐independent manner	6
Enzymatic Behavior of Condoliase in Porcine Nucleus Pulposus: Ex Vivo and In Vitro Assessment	6
Unilateral Lumbo‐Pelvic Fixation for Denis Type I Unilateral Sacral Fracture: A Finite Element Analysis	6
Is There a Positive or Negative Correlation Between Cervical Vertebral Bone Quality and Intervertebral Disc Degeneration by Pfirrmann Grading	6
Evaluating the causal effect of atherosclerosis on the risk of intervertebral disc degeneration	6
Socioeconomic status, mental health, and nutrition are the principal traits for low back pain phenotyping: Data from the osteoarthritis initiative	5
Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration	5
Mechanical crosstalk between the intervertebral disc, facet joints, and vertebral endplate following acute disc injury in a rabbit model	5
Consolidating and re‐evaluating the human disc nutrient microenvironment	5
Differential efficacy of two small molecule PHLPP inhibitors to promote nucleus Pulposus cell health	5
Phosphatidylethanolamine Protects Nucleus Pulposus Cells From Oxidative Stress‐Induced Cellular Senescence and Extracellular Matrix Degradation by Promoting Autophagy	5
A successful PSRS special issue and Spine across the globe	5
Understanding the etiopathogenesis of lumbar intervertebral disc herniation: From clinical evidence to basic scientific research	5
Comparative proteome analysis of the ligamentum flavum of patients with lumbar spinal canal stenosis	5
Pain behavior and phenotype in a modified anterior lumbar disc puncture mouse model	5
Correlation between motor behavior and age‐related intervertebral disc degeneration in cynomolgus monkeys	5
Comprehensive Evaluation of Facet Joints Osteoarthritis Radiological Features on Lumbar CT: A Multitask Deep Learning Approach	5
Epidemiology of Modic changes in dogs: Prevalence, possible risk factors, and association with spinal phenotypes	5
An in‐depth analysis of the immunomodulatory mechanisms of intervertebral disc degeneration	5
Characterization and modulation of the pro‐inflammatory effects of immune cells in the canine intervertebral disk	5
	5
Ex Vivo and In Vitro Proteomic Approach to Elucidate the Relevance of IL‐4 and IL‐10 in Intervertebral Disc Pathophysiology	5
Threats and opportunities of using ChatGPT in scientific writing—The risk of getting spineless	4
Intradiscal administration of autologous platelet‐rich plasma in patients with Modic type 1 associated low back pain: A prospective pilot study	4
Pharmacokinetics of PP353, a formulation of linezolid for intervertebral disc administration, in patients with chronic low back pain and Modic change Type 1: A first‐in‐human, Phase 1b, ope	4
Automatic grading of intervertebral disc degeneration in lumbar dog spines	4
Inactivation of Tnf‐α/Tnfr signaling attenuates progression of intervertebral disc degeneration in mice	4
Short‐Term Dynamic Unloading of Bovine Tail Discs in Culture Partially Mitigates Induced Degeneration After One‐Strike Trigger	4
Another milestone, accomplished!	4
Reduced Shear Modulus and Altered Lamellar Morphology of the Outer Annulus Fibrosus in Painful Intervertebral Disc Degeneration Compared With Tissue From Non‐Surgical Controls	4
Transcriptome Data Combined With Mendelian Randomization Analysis Identifies Key Genes Associated With Mitochondria and Programmed Cell Death in Intervertebral Disc Degeneration	4
Neural network segmentation of disc volume from magnetic resonance images and the effect of degeneration and spinal level	4
Phosphorylated heat shock protein 27 improves the bone formation ability of osteoblasts and bone marrow stem cells from patients with adolescent idiopathic scoliosis	4
Novel 3D printed lattice structure titanium cages evaluated in an ovine model of interbody fusion	4
DeVa (Decay Variance): A Novel Score Calculated via Postprocessing the Changes in Signal Intensity of an Intervertebral Disc in a T2* Multi‐Echo Magnetic Resonance Image Can Quan	4
Facet deflection and strain are dependent on axial compression and distraction in C5–C7 spinal segments under constrained flexion	4
The involvement of immune system in intervertebral disc herniation and degeneration	4
Non‐enzymatic glycation reduces glucose transport in the human cartilage endplate independently of matrix porosity or proteoglycan content	4
Spatial and Diurnal Variations in Sodium Content Within Intervertebral Disc Tissue	4
Demographic and Biomedical Characteristics of an Observational Cohort With Chronic Low Back Pain: A Descriptive Analysis	4
pH: A major player in degenerative intervertebral disks	4
Mechanistic Interactions Driving Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration: A Multi‐Axial Perspective of Mechanical, Immune, and Metabolic Pathways	3
Harmonization and standardization of nucleus pulposus cell extraction and culture methods	3
Welcome to Volume 5!	3
Application and Validation of Semiautomatic Quantification of Immunohistochemically Stained Sections for Low Cellular Tissue Such as Intervertebral Disc Using QuPath	3
Animal Models of Disc Degeneration Using Puncture Injury: A 20 Year Perspective	3
Slow twitch paraspinal muscle dysregulation in adolescent idiopathic scoliosis exhibiting HIF‐2α misexpression	3
A missense GDF5 variant causes brachydactyly type A1 and multiple‐synostoses syndrome 2	3
An additively manufactured model for preclinical testing of cervical devices	3
In Vivo Measurements Reveal Increased Nucleus Pulposus Lactate and Oxygen Concentrations in a Goat Model of Intervertebral Disc Degeneration	3
Bioinformatics‐based discovery of intervertebral disc degeneration biomarkers and immune‐inflammatory infiltrates	3
Chondrodystrophic Dogs as a Preclinical Large Animal Model of Discogenic Back Pain	3
Flexible support material maintains disc height and supports the formation of hydrated tissue engineered intervertebral discs in vivo	3
High‐Resolution 3‐Dimensional Micro‐ CT Imaging of Intervertebral Discs Using a Novel Contrast Agent	3
Biomolecular therapies for chronic discogenic low back pain: A narrative review	3
E74‐like ETS transcription factor 3 expression and regulation in human intervertebral disc	2
Wharton's Jelly mesenchymal stromal cell‐derived extracellular vesicles promote nucleus pulposus cell anabolism in an in vitro 3D alginate‐bead culture model	2
Intervertebral Disc Degeneration Mediates the Causal Effect of Genetically Predicted Diffuse Idiopathic Skeletal Hyperostosis on Spinal Stenosis: Evidence From a Mendelian Randomization Study	2
Development and validation of deep learning models for identifying the brand of pedicle screws on plain spine radiographs	2
In vivo fluid transport in human intervertebral discs varies by spinal level and disc region	2
Correction to ‘Recommendations for intervertebral disc notochordal cell investigation: From isolation to characterization’	2
The association between low virulence organisms in different locations and intervertebral disc structural failure: A meta‐analysis and systematic review	2
Injury Induces More Severe Biomechanical Changes in Middle‐Aged and Geriatric Lumbar Spines in a Mouse Ex Vivo Model	2
Annulus Fibrosus Repair via Interpenetration of a Non‐Woven Scaffold Supports Tissue Integration and Prevents Re‐Herniation	2
Collagen integrity of the annulus fibrosus in degenerative disc disease individuals quantified with collagen hybridizing peptide	2
Development of a mouse model of chronic ventral spinal cord compression: Neurobehavioral, radiological, and pathological changes	2
The degenerative impact of hyperglycemia on the structure and mechanics of developing murine intervertebral discs	2
Variations in ECM Topography, Fiber Alignment, Mechanical Stiffness, and Cellular Composition Between Ventral and Dorsal Ligamentum Flavum Layers: Insights Into Hypertrophy Pathogenesis	2
Issue Information	2
Automated magnetic resonance imaging‐based grading of the lumbar intervertebral disc and facet joints	2
Transcriptomic profiling reveals key early response genes during GDF6‐mediated differentiation of human adipose‐derived stem cells to nucleus pulposus cells	2
The potential effect of romosozumab on perioperative management for instrumentation surgery	2
A pilot study: Nano‐hydroxyapatite‐PEG/PLA containing low dose rhBMP2 stimulates proliferation and osteogenic differentiation of human bone marrow derived mesenchymal stem cells	2

Advancing basic and preclinical spine research: Highlights from the ORS PSRS 6th International Spine Research Symposium	2
The influence of ligament biomechanics on proximal junctional kyphosis and failure in patients with adult spinal deformity	2
Advancing spinal research beyond COVID‐19	2
The influence of intervertebral disc overloading on nociceptor calcium flickering	2
Issue Information	2
Improving how orthopedic journals report research outcomes based on sex and gender	2
Wharton's Jelly Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Attenuate Intervertebral Disc Degeneration Under Inflammatory Stress in an In Vitro 3D Culture System	2
Issue Information	2
Thoracolumbar Biomechanical Analysis of Lenke Type 1 Adolescent Idiopathic Scoliosis Across Roussouly Classifications	2
Ultrafine‐Grained Materials With Antibacterial Properties: A Novel Approach to Reducing Spinal Implant‐Associated Infections	2
A Conceptual Review of Naturally Occurring Toxins and Venoms as Peptide Blockers to Combat Chronic Low Back Pain	2
Developmental morphogens direct human induced pluripotent stem cells toward an annulus fibrosus‐like cell phenotype	2
Controversies in spine research: Organ culture versus in vivo models for studies of the intervertebral disc	2
An exploration of knowledge‐organizing technologies to advance transdisciplinary back pain research	2
Macrophage Subtypes Distinctly Impact Intervertebral Disc Inflammation and Extracellular Matrix Composition	1
Combining adhesive and nonadhesive injectable hydrogels for intervertebral disc repair in an ovine discectomy model	1
Development and Validation of a Machine Learning‐Based Online Prognostic Model for Cervical Spondylosis Patients After Anterior Cervical Discectomy and Fusion: A Multicenter Study	1
Diverse and multifunctional roles for perlecan (HSPG2) in repair of the intervertebral disc	1
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Regenerative Potential of Extracellular Vesicles on Intervertebral Disc Degeneration: What is the EV‐idence ?	1
Development of normalized quantitative measures of lumbar disc degeneration	1
Efficacy of using autologous cells with graft substitutes for spinal fusion surgery: A systematic review and meta‐analysis of clinical outcomes and imaging features	1
Issue Information	1
Issue Information	1
Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning	1
Evaluation of a Force‐Control Experimental Method to Perform Unconstrained Load‐Induced Subsidence Testing of Spinal Interbody Implants	1
Fibrotic and inflammatory characteristics of epidural fat adjacent to the ossification area in patients with ossification of the ligament flavum	1
Range of international surgical strategies for adolescent idiopathic scoliosis: Evaluation of a multi‐center survey	1
Contemporary clinical perspectives on chronic low back pain: The biology, mechanics, etc. underpinning clinical and radiological evaluation	1
Targeted screening of inflammatory mediators in spontaneous degenerative disc disease in dogs reveals an upregulation of the tumor necrosis superfamily	1
Species variation in the cartilaginous endplate of the lumbar intervertebral disc	1
Proteomic analysis of serum in a population‐based cohort did not reveal a biomarker for Modic changes	1
Relationship Between Quantitative MRI and Radiological, Histological, and Biochemical Measures of Intervertebral Disc Health in Client‐Owned, Nonchondrodystrophic‐Breed Dogs	1
Targeting nucleus pulposus cell death in the treatment of intervertebral disc degeneration	1
Revealing the novel metabolism‐related genes in the ossification of the ligamentum flavum based on whole transcriptomic data	1
Investigation into theanti‐inflammatoryproperties of metformin in intervertebral disc cells	1
Therapeutic Approaches for Enhancing Spinal Fusion in Low Back Pain: A Review With a Focus on the Elderly	1
Issue Information	1
PHLPP1 deficiency protects against age‐related intervertebral disc degeneration	1
In Vitro Validation of Pulsed Electromagnetic Field (PEMF) as an Effective Countermeasure Against Inflammatory‐Mediated Intervertebral Disc Degeneration	1
Influence of macrophage polarization in herniated nucleus pulposus tissue on clinical efficacy after lumbar discectomy	1
Integrated DNA methylation analysis reveals a potential role for PTPRN2 in Marfan syndrome scolios	1
Relationship Between Lumbar Multifidus Morphometry and Pain/Disability in Individuals With Chronic Nonspecific Low Back Pain After Considering Demographics, Fear‐Avoidance Beliefs, Insomnia, and Spina	1
Automated Computational Pathology to Assess Degenerative Disc Histology	1
DLX5 regulates the osteogenic differentiation of spinal ligaments cells derived from ossification of the posterior longitudinal ligament patients via NOTCH signaling	1
SSR1andCKAP4as potential biomarkers for intervertebral disc degeneration based on integrated bioinformatics analysis	1
Comparative Finite Element Analysis of Denosumab and Bazedoxifene on Pedicle Screw Stability in Osteoporotic Spines	1
Dynamics of N6‐methyladenosine modification during aging and their potential roles in the degeneration of intervertebral disc	1
Effects of circulating inflammatory proteins on spinal degenerative diseases: Evidence from genetic correlations and Mendelian randomization study	1
Introduction to a Special Issue Describing an Observational Cohort of Adults With Chronic Low Back Pain	1
Complex In Vivo Motion of the Bovine Tail Provides Unique Insights Into Intervertebral Disc Adaptation	1
Causal Relationship Between Gut Microbiota, Blood Metabolites, and Intervertebral Disc Degeneration: A Two‐Step, Two‐Sample Bidirectional Mendelian Randomization Study	1
Intervertebral Disc Proteoglycans: Multifunctional Tissue Stabilizing and Instructional Cell Regulatory Proteins That Control Tissue Homeostasis	1
An update on animal models of intervertebral disc degeneration and low back pain: Exploring the potential of artificial intelligence to improve research analysis and development of prospective therape	1
Lovastatin‐Loaded Nanoparticles in a Thermosensitive Chitosan Hydrogel as a Sustained Release System for Treating Intervertebral Disc Degeneration: In Vitro Cell Culture Study and In Vivo Evaluation U	1
Assessment of Vertebral Bone Marrow Perfusion, Fat/Water Content, and Trabecular Bone Changes Using Multimodal MRI and Micro‐CT in a Rat Model of Chronic Kidney Disease	1
Crosstalk Between Ferroptosis and Cuproptosis in Intervertebral Disc Degeneration: Mechanisms, Therapeutic Targets, and Future Directions	1
Validation of a Coordinate Optimization Approach for Assessment of In Vivo Intervertebral Kinematics in Patients With Adult Spinal Deformity and Healthy Older Adults	1
JOR Spine: Reaping the harvest of a community effort	1
A novel spine tester TO GO	1
The role of the complement system in disc degeneration and Modic changes	1
Mechanism of Intervertebral Disc Degeneration via the β‐Catenin/CCL2 Pathway in Sox9 Conditional Knockout Mice	1
TRPV4 differentially controls inflammatory cytokine networks during static and dynamic compression of the intervertebral disc	1