OOIR: Observatory of International Research

Papers

(The TQCC of JOR Spine is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Vascularization of the human intervertebral disc: A scoping review	60
Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the ORS spine section	50
Paraspinal muscle pathophysiology associated with low back pain and spine degenerative disorders	45
The involvement of immune system in intervertebral disc herniation and degeneration	40
Density and mechanical properties of vertebral trabecular bone—A review	37
Development of a standardized histopathology scoring system using machine learning algorithms for intervertebral disc degeneration in the mouse model—An ORS spine section initiative	34
Cell sources proposed for nucleus pulposus regeneration	33
Spine biomechanical testing methodologies: The controversy of consensus vs scientific evidence	30
Development of a standardized histopathology scoring system for human intervertebral disc degeneration: an Orthopaedic Research Society Spine Section Initiative	27
Electrospinning and 3D bioprinting for intervertebral disc tissue engineering	22
Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha	22
Advanced glycation end products cause RAGE‐dependent annulus fibrosus collagen disruption and loss identified using in situ second harmonic generation imaging in mice intervertebral disk in	21
Using embedded alginate microparticles to tune the properties of in situ forming poly(N‐isopropylacrylamide)‐graft‐chondroitin sulfate bioadhesive hydrogels for replacement and repair of the nu	21
Optimization of a rat lumbar IVD degeneration model for low back pain	21
Adolescent idiopathic scoliosis: The mechanobiology of differential growth	21
A comprehensive tool box for large animal studies of intervertebral disc degeneration	20
Intervertebral disc degeneration and how it leads to low back pain	18
Paraspinal muscle morphology and composition in adolescent idiopathic scoliosis: A histological analysis	17
The effects of 3D culture on the expansion and maintenance of nucleus pulposus progenitor cell multipotency	16
Preclinical models of vertebral osteomyelitis and associated infections: Current models and recommendations for study design	16
Spatial mapping of collagen content and structure in human intervertebral disk degeneration	15
Patient‐specific apparent diffusion maps used to model nutrient availability in degenerated intervertebral discs	14
Structure‐function relationships of the human vertebral endplate	14
Development of a standardized histopathology scoring system for intervertebral disc degeneration and regeneration in rabbit models‐An initiative of the ORSspine section	13
Canine models of spine disorders	13

Intervertebral disc herniation effects on multifidus muscle composition and resident stem cell populations	12
Influence of testing environment and loading rate on intervertebral disc compressive mechanics: An assessment of repeatability at three different laboratories	12
Automatic detection and voxel‐wise mapping of lumbar spine Modic changes with deep learning	11
Effects of suppressing bioavailability of insulin‐like growth factor on age‐associated intervertebral disc degeneration	11
Assessing the use of finite element analysis for mechanical performance evaluation of intervertebral body fusion devices	11
Atomic force microscopy imaging for nanoscale and microscale assessments of extracellular matrix in intervertebral disc and degeneration	11
Multiaxial validation of a finite element model of the intervertebral disc with multigenerational fibers to establish residual strain	11
An update on animal models of intervertebral disc degeneration and low back pain: Exploring the potential of artificial intelligence to improve research analysis and development of prospective therape	10
Consolidating and re‐evaluating the human disc nutrient microenvironment	10
Characterization of bovine and canine animal model cartilage endplates and comparison to human cartilage endplate structure, matrix composition, and cell phenotype	10
An in‐depth analysis of the immunomodulatory mechanisms of intervertebral disc degeneration	10
Generation of an in vitro model of the outer annulus fibrosus‐cartilage interface	10
Effects of systemically administered abaloparatide, an osteoanabolic PTHrP analog, as an adjuvant therapy for spinal fusion in rats	9
A challenging playing field: Identifying the endogenous impediments to annulus fibrosus repair	9
Immunohistochemical analysis of protein expression in formalin fixed paraffin embedded human intervertebral disc tissues	9
TRPV4 mediates cell damage induced by hyperphysiological compression and regulates COX2/PGE2 in intervertebral discs	9
Effect of different cryopreservation media on human nucleus pulposus cells' viability and trilineage potential	9
Injectable decellularized nucleus pulposus tissue exhibits neuroinhibitory properties	9
Clinically relevant finite element technique based protocol to evaluate growing rods for early onset scoliosis correction	9
Preclinical in vivo animal models of intervertebral disc degeneration. Part 1: A systematic review	8
Single‐cell RNA Seq reveals cellular landscape‐specific characteristics and potential etiologies for adolescent idiopathic scoliosis	8
Intradiscal injection for the management of low back pain	8
The degenerative impact of hyperglycemia on the structure and mechanics of developing murine intervertebral discs	8
Investigating the physiological relevance of ex vivo disc organ culture nutrient microenvironments using in silico modeling and experimental validation	8
Rat tail models for the assessment of injectable nucleus pulposus regeneration strategies	7
Quantitative identification and segmentation repeatability of thoracic spinal muscle morphology	7
Verteporfin treatment controls morphology, phenotype, and global gene expression for cells of the human nucleus pulposus	7
Confocal scanning of intervertebral disc cells in 3D: Inside alginate beads and in native microenvironment	7
Axial hypersensitivity is associated with aberrant nerve sprouting in a novel model of disc degeneration in female Sprague Dawley rats	7
Comparison and optimization of sheep in vivo intervertebral disc injury model	7
Validity of flexicurve and motion capture for measurements of thoracic kyphosis vs standing radiographic measurements	7
Mechanical and biological characterization of a composite annulus fibrosus repair strategy in an endplate delamination model	7
Percutaneous lumbar annular puncture: A rat model to study intervertebral disc degeneration and pain‐related behavior	7
An optimized step‐by‐step protocol for isolation of nucleus pulposus, annulus fibrosus, and end plate cells from the mouse intervertebral discs and subsequent preparation of high‐quality intact total	7
Harmonization and standardization of nucleus pulposus cell extraction and culture methods	6
Age‐related molecular changes in the lumbar dorsal root ganglia of mice: Signs of sensitization, and inflammatory response	6
Protocol for parallel proteomic and metabolomic analysis of mouse intervertebral disc tissues	6
COVID‐19: Current and future challenges in spine care and education ‐ a worldwide study	6
N‐acetylcysteine attenuates oxidative stress‐mediated cell viability loss induced by dimethyl sulfoxide in cryopreservation of human nucleus pulposus cells: A potential solution for mass produc	6
Biomedical applications of silk and its role for intervertebral disc repair	6
Single level posterolateral lumbar fusion in a New Zealand White rabbit (Oryctolagus cuniculus) model: Surgical anatomy, operative technique, autograft fusion rates, and perioperativ	6