OOIR: Observatory of International Research

Papers

(The TQCC of CRISPR Journal is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Increasing Genome Editing Efficiency of Cas9 Nucleases by the Simultaneous Use of Transcriptional Activators and Histone Acetyltransferase Activator	47
CRISPR Comparison Toolkit: Rapid Identification, Visualization, and Analysis of CRISPR Array Diversity	37
Hairpin Internal Nuclear Localization Signals in CRISPR-Cas9 Enhance Editing in Primary Human Lymphocytes	36
Adaptation by Type V-A and V-B CRISPR-Cas Systems Demonstrates Conserved Protospacer Selection Mechanisms Between Diverse CRISPR-Cas Types	35
Will Advances in Genetic Medicine Lessen the Need for Germline Modifications?	33
Exploring the Cytoplasmic Retention of CRISPR-Cas9 in Eukaryotic Cells: The Role of Nuclear Localization Signals and Ribosomal Interactions	29
Subtypes of Type I-E CRISPR-Cas Systems Distribution in Human Escherichia coli Isolates from China	29
Gene Editing Corrects In Vitro a G > A GLB1 Transition from a GM1 Gangliosidosis Patient	28
Novel CRISPR-Associated Gene-Editing Systems Discovered in Metagenomic Samples Enable Efficient and Specific Genome Engineering	23
Opposing Human Genetic Engineering	23
The Lexicon of CRISPR: When Is It Too Much?	22
Acknowledgment of Reviewers 2022	20
Curing “GFP-itis” in Bacteria with Base Editors: Development of a Genome Editing Science Program Implemented with High School Biology Students	20
Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas	18
Advances in Cas12a-Based Amplification-Free Nucleic Acid Detection	18
Gene Editing and Rett Syndrome: Does It Make the Cut?	17
Efficient Installation of Heterozygous Mutations in Human Pluripotent Stem Cells Using Prime Editing	16
Early Detection of Wildlife Disease Pathogens Using CRISPR-Cas System Methods	16
CRISPR Crops and Sustainable Agriculture	15
Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing	15
Comprehensive Analysis of CRISPR-Cas9 Editing Outcomes in Yeast Xanthophyllomyces dendrorhous	15
Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors	14
The Roles and Responsibilities of Scientific Journals in Research Governance: Editorial Policymaking at Nature and Springer Nature (1995–2023)	14
CRISPR-Cas9 Single Nucleotide Editing of Tuberous Sclerosis Complex 2 Gene in Mesenchymal Stem Cells	13
Viability-Based Assessment Reveals True Efficiency of CRISPR-Cas9 Transfection Methods in Rabbit Spermatozoa	13

Engineered Antiviral Sensor Targets Infected Mosquitoes	13
Automated Good Manufacturing Practice-Compatible CRISPR-Cas9 Editing of Hematopoietic Stem and Progenitor Cells for Clinical Treatment of β-Hemoglobinopathies	12
Regulatory Support for CRISPR in Ag: A Timely EU-Turn	12
Widespread Impact of Natural Genetic Variations in CRISPR-Cas9 Outcomes	12
Gene Editing in the Chagas Disease Vector Rhodnius prolixus by Cas9-Mediated ReMOT Control	12
Specific High-Sensitivity Enzymatic Reporter UnLOCKing-Mediated Detection of Oncogenic BCR::ABL1 and EGFR	12
A Story of Perseverance: An Interview with Matthew Porteus	12
Institutional Bioethics: From Critical Interdisciplinarity to Cosmopolitanism	12
Fanzors: Mysterious TnpB-Like Bacterial Transposon-Related RNA-Guided DNA Nucleases of Eukaryotes	11
Enhancements of the CRISPR-Cas System in the Silkworm Bombyx mori	11
CRISPR Momentum in the Clinic and the Field	11
Engineering CjCas9 for Efficient Base Editing and Prime Editing	11
A PCR-Induced Mutagenesis-Restriction Fragment Length Polymorphism Method for the Detection of CRISPR-Induced Indels	11
Efficient CRISPR-Cas9-Mediated Genome Editing of the Cane Toad ( Rhinella marina )	11
dCas9 Tells Tales: Probing Gene Function and Transcription Regulation in Cancer	11
A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors	10
Conditional Expression of Cas9 and dCas9 in Lucilia cuprina Reveals dCas9-Associated Lethality	10
Affordable Pricing of CRISPR Treatments is a Pressing Ethical Imperative	10
A Protein-Cutting CRISPR Complex Caught in Action	10
A Multiplexed Cas13-Based Assay with Point-of-Care Attributes for Simultaneous COVID-19 Diagnosis and Variant Surveillance	10
Warrior Spirit: An Interview with Victoria Gray, Sickle Cell Pioneer	9
It's a Knockout for Cat Allergies?	9
The CRISPR Revolution in the Drug Discovery Workflow: An Industry Perspective	9
Cas12a-Capture: A Novel, Low-Cost, and Scalable Method for Targeted Sequencing	9
CRISPR-Cas9-Mediated Correction of TSC2 Pathogenic Variants in iPSCs from Patients with Tuberous Sclerosis Complex Type 2	9
Rapid and Technically Simple Detection of SARS-CoV-2 Variants Using CRISPR Cas12 and Cas13	9
Navigating Viral Space with CRISPR Technologies	8
Acknowledgment of Reviewers 2023	8
Rapid Variant Pathogenicity Analysis by CRISPR Activation of CRB1 Gene Expression in Patient-Derived Fibroblasts	8
Introducing Faith-Based Claims to Ethical Discourse on Scientific Matters	8
The New Old Colonialism	7
Five Years of Progress in CRISPR Clinical Trials (2019–2024)	7
Strategies for Interdisciplinary Human Gene Editing Research: Insights from a Swiss Project	7
Reduction of Pre-Existing Adaptive Immune Responses Against SaCas9 in Humans Using Epitope Mapping and Identification	7
Genome Editing Therapy for the Blood: Ex Vivo Success and In Vivo Prospects	7
Trichostatin A for Efficient CRISPR-Cas9 Gene Editing of Human Pluripotent Stem Cells	7
CRISPR Medicine Needs Infrastructure, Not Just Innovation	7
Genome Editing Headwinds: Can CRISPR Stay on Target?	7