Circulation-Genomic and Precision Medicine

Papers
(The TQCC of Circulation-Genomic and Precision Medicine is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
MYH7 p.Glu903Gln Is a Pathogenic Variant Associated With Hypertrophic Cardiomyopathy154
Multiomic Profiling in Black and White Populations Reveals Novel Candidate Pathways in Left Ventricular Hypertrophy and Incident Heart Failure Specific to Black Adults106
Evaluating the Cardiometabolic Efficacy and Safety of Lipoprotein Lipase Pathway Targets in Combination With Approved Lipid-Lowering Targets: A Drug Target Mendelian Randomization Study90
Compound Heterozygous Truncating Variants in the BAG5 Gene As a Cause of Early-Onset Dilated Cardiomyopathy72
Retraction of: Systematic Evaluation of KCNQ1 variant using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 167
Pregnancy Outcomes in Females With Dilated Cardiomyopathy–Associated Rare Genetic Variants55
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes50
Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT40
Clinical Characteristics of SCN5A p.R965C Carriers: A Common Founder Variant Predisposing to Brugada Syndrome in Thailand33
Genome-Wide De Novo Variants in Congenital Heart Disease Are Not Associated With Maternal Diabetes or Obesity31
How Normal Is Low-Normal Left Ventricular Ejection Fraction in Familial Dilated Cardiomyopathy?30
Polygenic Risk and Coronary Artery Disease Severity27
Reproductive Carrier Screening: Identifying Families at Risk for Familial Hypercholesterolemia in the United States27
Hidden Risk: Arrhythmogenic Genes in the General Population23
Genetically Predicted Pulse Pressure and Risk of Abdominal Aortic Aneurysm: A Mendelian Randomization Analysis23
Mulibrey Nanism and the Real Time Use of Genome and Biobank Engines to Inform Clinical Care in an Ultrarare Disease23
Cardioinformatics Advancements in Healthcare and Biotechnology22
Rare Genetic Variants Associated With Sudden Cardiac Arrest in the Young: A Prospective, Population-Based Study22
Correction to: Coassin et al, Genome-Wide Characterization of a Highly Penetrant Form of Hyperlipoprotein(a)emia Associated With Genetically Elevated Cardiovascular Risk21
Editorial Board21
Prognostic Implications Between hsCRP and CYP2C19 Genotype in Patients From East Asia: Insights From the PTRG-DES Consortium20
Lipoprotein(a) Atherosclerotic Cardiovascular Disease Risk Score Development and Prediction in Primary Prevention From Real-World Data20
Recent Advances on the Genetics of Spontaneous Coronary Artery Dissection20
Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course20
Molecular Management of Multifocal Atrial Tachycardia in Noonan’s Syndrome With MEK1/2 Inhibitor Trametinib19
CHDgene: A Curated Database for Congenital Heart Disease Genes19
Accelerated Epigenetic Aging Is Associated With Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health Substudy18
Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults18
Admixture Mapping of Chronic Kidney Disease and Risk Factors in Hispanic/Latino Individuals From Central America Country of Origin18
Novel SCN5A Variant Shows Multiple Phenotypic Expression in the Same Family18
Development of a Patient-Specific p.D85N-Potassium Voltage-Gated Channel Subfamily E Member 1–Induced Pluripotent Stem Cell–Derived Cardiomyocyte Model for Drug-Induced Long QT Syndrome18
Life-Time Covariation of Major Cardiovascular Diseases18
Plasma Proteomic Profile Predicts Survival in Heart Failure With Reduced Ejection Fraction18
Variant Location Is a Novel Risk Factor for Individuals With Arrhythmogenic Cardiomyopathy Due to a Desmoplakin ( DSP ) Truncating Variant18
Rapidly Progressive Peripheral Artery Disease: Importance of Oligogenic Inheritance and Functional Validation18
Polygenic Scoring for Detection of Ascending Thoracic Aortic Dilation17
Phenotypic Spectrum of Subclinical Sarcomere-Related Hypertrophic Cardiomyopathy and Transition to Overt Disease17
Validation of a Polygenic Score for Beta-Blocker Survival Benefit in Patients With Heart Failure Using the United Kingdom Biobank17
Heritability of Atrial Fibrillation Among Swedish Adoptees16
Enhancing the Prediction Power of Polygenic Risk Scores in Genetically Diverse Coronary Heart Disease16
Long-Term Prevalence of Systolic Dysfunction in MYBPC3 Versus MYH7-Related Hypertrophic Cardiomyopathy15
Dilated Cardiomyopathy With Concomitant Salt-Losing Renal Tubulopathy Caused by Heterozygous RRAGD Gene Variant15
System Genetics Including Causal Inference Identify Immune Targets for Coronary Artery Disease and the Lifespan15
Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Choleste15
Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization15
Meta-Analysis of Genome-Wide Association Studies Reveals Genetic Mechanisms of Supraventricular Arrhythmias14
DNA Damage Response and Repair Genes and Anthracycline-Induced Cardiomyopathy in Childhood Cancer Survivors: A Report From the Children’s Oncology Group and the Childhood Cancer Survivor Study14
Transcription Factors Leave Their Mark on the Heart14
Suppression and Replacement Gene Therapy for KCNH2 -Mediated Arrhythmias14
Clinical Implications of SCN10A Loss-of-Function Variants in 169 610 Exomes Representing the General Population14
Long-term Effects of Mavacamten on Patients Based on Hypertrophic Cardiomyopathy Pathogenic Genetic Variant Status: Insights from VALOR-HCM Trial13
Investigation of Copy Number Variation in South African Patients With Congenital Heart Defects13
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopa13
Current State and Future of Polygenic Risk Scores in Cardiometabolic Disease: A Scoping Review13
Single-Cell Dissection of the Immune Response After Acute Myocardial Infarction13
Is There a Role for Genetic Testing in Patients With Myocarditis?12
Role of TBX20 Truncating Variants in Dilated Cardiomyopathy and Left Ventricular Noncompaction12
Metabolite Signature of Life’s Essential 8 and Risk of Coronary Heart Disease Among Low-Income Black and White Americans12
Long-Read Sequence Confirmed a Large Deletion Including MYH6 and MYH7 in an Infant of Atrial Septal Defect and Atrial Arrhythmias11
Homozygous SPEG Mutation Is Associated With Isolated Dilated Cardiomyopathy11
Genetic Effect on Body Mass Index and Cardiovascular Disease Across Generations11
Novel Insights Into DMD-Associated Dilated Cardiomyopathy11
Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses11
DiscoVari : A Web-Based Precision Medicine Tool for Predicting Variant Pathogenicity in Cardiomyopathy- and Channelopathy-Associated Genes10
Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk Prediction10
Genetic European Ancestry and Incident Diabetes in Black Individuals: Insights From the SPRINT Trial10
Multi-Trait Genetic Analysis Reveals Clinically Interpretable Hypertension Subtypes10
Common SYNE2 Genetic Variant Associated With Atrial Fibrillation Lowers Expression of Nesprin-2α1 With Downstream Effects on Nuclear and Electrophysiological Traits10
Cardiovascular Disease Knowledge Portal: A Community Resource for Cardiovascular Disease Research10
Association of Plasma Branched-Chain Amino Acid With Biomarkers of Inflammation and Lipid Metabolism in Women10
Clinical Outcomes and Genetic Analyses of Restrictive Cardiomyopathy in Children10
Circulating Blood Plasma Profiling Reveals Proteomic Signature and a Causal Role for SVEP1 in Sudden Cardiac Death10
Polygenic Risk in Families With Dilated Cardiomyopathy10
Cardiomyopathy Genes and Idiopathic VF: A Known Unknown?9
Prediction of Coronary Artery Disease and Major Adverse Cardiovascular Events Using Clinical and Genetic Risk Scores for Cardiovascular Risk Factors9
Low-Cost High-Throughput Genotyping for Diagnosing Familial Hypercholesterolemia9
Ultra-Rapid Nanopore Whole Genome Genetic Diagnosis of Dilated Cardiomyopathy in an Adolescent With Cardiogenic Shock9
Communal Coping as a Strategy to Enhance Family Engagement in Dilated Cardiomyopathy9
Calmodulinopathy Associated Long QT Syndrome, Hypertrophic Cardiomyopathy With Excessive Trabeculation in a 14-Year-Old Girl Presenting With Ventricular Fibrillation9
Incremental Value of a Metabolic Risk Score for Heart Failure Mortality: A Population-Based Study9
The Genetic Basis of Primary Cardiomyopathies in Childhood: Implications for Clinical Genetic Testing9
Coronary Artery Disease Polygenic Risk Score Identifies Patients at Higher Risk for Recurrent Cardiovascular Events in the CANTOS Trial9
Early Childhood-Onset Hypertrophic Cardiomyopathy in a Family With an In-Frame MYH7 Deletion9
Genetically Predicted Lipid Traits, Diabetes Liability, and Carotid Intima-Media Thickness in African Ancestry Individuals: A Mendelian Randomization Study9
Causal Relationship Between Average Alcohol Consumption and Risk of Atrial Fibrillation: A Mendelian Randomization Study9
PRDM16 Deletion Is Associated With Sex-dependent Cardiomyopathy and Cardiac Mortality: A Translational, Multi-Institutional Cohort Study9
Splicing Functional Assays Into the Genetic Testing Pipeline9
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