iScience

Article	Citations
Nuclear transfer improves the developmental potential of embryos derived from cytoplasmic deficient oocytes	418
Matter-wave gap solitons and vortices in three-dimensional parity-time-symmetric optical lattices	221
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps	219
Functional genomic analysis of Candida albicans protein kinases reveals modulators of morphogenesis in diverse environments	194
Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism	189
Risk of cerebrovascular disease after cancer diagnosis in the United States	172
Visual deprivation induces a stronger dive response in a harbor porpoise	166
MIF-like domain containing protein orchestrates cellular differentiation and virulence in the fungal pathogen Magnaporthe oryzae	139
MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myeloma	138
MAP3K19 regulatory variation in populations with African ancestry may increase COVID-19 severity	128
The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress	124
The Prc and CtpA proteases modulate cell-surface signaling activity and virulence in Pseudomonas aeruginosa	123
Murine double minute 2 aggravates adipose tissue dysfunction through ubiquitin-mediated six-transmembrane epithelial antigen of prostate 4 degradation	115
Longitudinal cohort study highlights cancer-preventive benefits of lipid-lowering drugs	112
Lifespan associations of resting-state brain functional networks with ADHD symptoms	111
Activity-based protein profiling of human and plasmodium serine hydrolases and interrogation of potential antimalarial targets	110
Overexpression and knockdown of cotton GhdadD gene reveals its drought and salt stress tolerance role	109
Transforming the CRISPR/dCas9-based gene regulation technique into a forward screening tool in Plasmodium falciparum	108
Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction	108
Cooperative RNA degradation stabilizes intermediate epithelial-mesenchymal states and supports a phenotypic continuum	105
A host lipase prevents lipopolysaccharide-induced foam cell formation	105
WITHDRAWN: Fibromodulin alleviates matrix stiffness-induced degeneration of the nucleus pulposus by regulating cytoskeleton and autophagy	103
Ecological firewalls for synthetic biology	103
Cytomegalovirus-specific neutralizing antibodies effectively prevent uncontrolled infection after allogeneic hematopoietic stem cell transplantation	101
Genome-wide analyses identify SCN5A as a susceptibility locus for premature atrial contraction frequency	98

Retraction Notice to: Modulation of TNFa Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration	95
A regulatory linkage between scytonemin production and hormogonia differentiation in Nostoc punctiforme	94
Selective modulator of nuclear receptor PPARγ with reduced adipogenic potential ameliorates experimental nephrotic syndrome	91
Development of a loop-mediated isothermal amplification (LAMP)-based electrochemical test for rapid detection of SARS-CoV-2	90
Electro-, thermo-, and photocatalysis of versatile nanocomposites toward tandem process	90
Ion adsorption promotes Frank-van der Merwe growth of 2D transition metal tellurides	89
Serum proteome profiling reveals heparanase as a candidate biomarker for chronic thromboembolic pulmonary hypertension	87
Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters	87
Touching with the eyes: Oculomotor self-touch induces illusory body ownership	87
A pilot study on a patient with refractory headache: Personalized deep brain stimulation through stereoelectroencephalography	87
Exploring the roles of intestinal flora in enhanced recovery after surgery	85
Integrative metabolomic and proteomic signatures define clinical outcomes in severe COVID-19	85
CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signaling pathway	84
IL-27 mediates immune response of pneumococcal vaccine SPY1 through Th17 and memory CD4+T cells	84
Perovskite-based photodetector for real-time and quantitative monitoring of sports motion	82
Insights into the hydrogen generation and catalytic mechanism on Co-based nanocomposites derived from pyrolysis of organic metal precursor	82
Tickle contagion in the rat somatosensory cortex	81
Sex peptide regulates female receptivity through serotoninergic neurons in Drosophila	80
Microhabitat-specific diurnal metabolomic responses of the intertidal limpet Cellana toreuma to winter low temperature	80
Attenuated humoral responses in HIV after SARS-CoV-2 vaccination linked to B cell defects and altered immune profiles	80
Mitochondrial translation is the primary determinant of secondary mitochondrial complex I deficiencies	80
Activity modulation of the Escherichia coli F1FO ATP synthase by a designed antimicrobial peptide via cardiolipin sequestering	79
Coexistence of large mammals and humans is possible in Europe's anthropogenic landscapes	78
Longitudinal monitoring of individual infection progression in Drosophila melanogaster	78
Understanding menstrual blood-derived stromal/stem cells: Definition and properties. Are we rushing into their therapeutic applications?	77
Unveiling the role of inorganic nanoparticles in Earth’s biochemical evolution through electron transfer dynamics	77
Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34+ progenitor cell-derived NK cells	76
Modulation of social investigation by anterior hypothalamic nucleus rhythmic neural activity	76
Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2	75
Detecting tandem repeat variants in coding regions using code-adVNTR	74
Pressure dependent thermoreflectance spectroscopy induced by interband transitions in metallic nano-film	72
DeepASmRNA: Reference-free prediction of alternative splicing events with a scalable and interpretable deep learning model	71
Derived myeloid lineage induced pluripotent stem as a platform to study human C-C chemokine receptor type 5Δ32 homozygotes	70
Prognostic significance of inflammation in patients with coronary artery disease at low residual inflammatory risk	69
Crosstalk between 6-methyladenine and 4-methylcytosine in Geobacter sulfurreducens exposed to extremely low-frequency electromagnetic field	69
Enhancing corrosion resistance of biodegradable magnesium with dicalcium phosphate dihydrate and Chlorella sp. biomass	69
Social rank-dependent effects of testosterone on huddling strategies in mice	69
The ATP-exporting channel Pannexin 1 promotes CD8+ T cell effector and memory responses	68
Multi-omic profiling of pathogen-stimulated primary immune cells	68
Panera: An innovative framework for surmounting uncertainty in microbial community modeling using pan-genera metabolic models	68
Chronic disease incidence explained by stepwise models and co-occurrence among them	68
Low intensity transcranial ultrasound stimulation induces hemodynamic responses through neurovascular coupling	67
Diminished representation of vitamin-B12-producing bacteria in constipated elders with frailty	67
Regulation of interstitial fluid flow in adventitia along vasculature by heartbeat and respiration	67
Stenotrophomonas maltophilia provokes NEU1-mediated release of a flagellin-binding decoy receptor that protects against lethal infection	66
Optically induced quantum transitions in direct probed mesoscopic NbSe2 for prototypical bolometers	66
Sample multiplexing for retinal single-cell RNA sequencing	66
A resource of high-quality and versatile nanobodies for drug delivery	66
Impact of myocardial reperfusion on human plasma lipidome	66
Advancements in coupled processes numerical models: Upscaling aperture fields using spatial continuity	66

Reverse subsidy dilemma caused by the transformation from individual heating to central heating	66
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life	64
Exploring the substrate stereoselectivity and catalytic mechanism of nonribosomal peptide macrocyclization in surugamides biosynthesis	64
Identification of mitochondria-related gene biomarkers associated with immune infiltration in acute myocardial infarction	64
Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis	64
The mitochondrial stress signaling tunes immunity from a view of systemic tumor microenvironment and ecosystem	64
A mathematical model of neuroimmune interactions in epileptogenesis for discovering treatment strategies	63
Neuron-glia interaction at the receptor level affects olfactory perception in adult Drosophila	63
Traffic noise inhibits inhibitory control in wild-caught songbirds	62
Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in patients with severe COVID-19	62
Tumor cell malignancy: A complex trait built through reciprocal interactions between tumors and tissue-body system	62
Temperature and livestock grazing trigger transcriptome responses in bumblebees along an elevational gradient	62
Release of extracellular DNA by Pseudomonas sp. as a major determinant for biofilm switching and an early indicator for cell population control	61
Protein-constrained models pinpoints the role of underground metabolism in robustness of metabolic phenotypes	61
Predictable sequential structure augments auditory sensitivity at threshold	61
Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models	60
Impact of ATF6 deletion on the embryonic brain development	59
Cell-based sialoglycan arrays for directly comparing influenza A virus receptor requirements for binding and infection	59
Predicting stroke and myocardial infarction risk in Takayasu arteritis with automated machine learning models	59
Cell surface heparan sulfate is an attachment receptor for grass carp reovirus	59
Predicting phage-host interaction via hyperbolic Poincaré graph embedding and large-scale protein language technique	58
A two-component cocktail of engineered DIII nanoparticles elicits broadly neutralizing antibody responses against dengue virus in mice	58
Sex differences in left-ventricular strain in a murine model of coxsackievirus B3 myocarditis	58
Eco-evolutionary feedbacks under artificial light at night	58
Abundant repressor binding sites in human enhancers are associated with the fine-tuning of gene regulation	58
Robustness of machine learning predictions for Fe-Co-Ni alloys prepared by various synthesis methods	58
TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination	58
Acute dietary methionine restriction triggers cell cycle arrest and reversible growth defects in the neocortex	57
NKG2D-CAR-targeted iPSC-derived MSCs efficiently target solid tumors expressing NKG2D ligand	57
Biophysical characterization of the recording of unmyelinated and myelinated fiber activity with peripheral interfaces	57
Bitter taste receptor T2R14-Gαi coupling mediates innate immune responses to microbial quorum sensing molecules in cystic fibrosis	56
Interdisciplinarity at the nexus of biomedical science training: The R3 Center for Innovation in Science Education	56
Oleuropein activates autophagy to circumvent anti-plasmodial defense	56
Single-cell immune profiling reveals broad anti-inflammation response in bipolar disorder patients with quetiapine and valproate treatment	56
Standardized two-step testing of antibody activity in COVID-19 convalescent plasma	55
Microbiome depletion prior to repeat mild TBI differentially alters social deficits and prefrontal cortex plasticity in adolescent and adult rats	55
Group 3 innate lymphocytes make a distinct contribution to type 17 immunity in bladder defence	55
Evidence of self-care tooling and phylogenetic modeling reveal parrot tool use is not rare	55
Terahertz waves regulate the mechanical unfolding of tau pre-mRNA hairpins	55
Multilingual multi-aspect explainability analyses on machine reading comprehension models	55
PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective	55
The attitudinal space framework: Embracing the multidimensionality of attitudinal diversity	55
Genomic analyses reveal three phylogenetic species and their evolutionary histories in the big-headed turtle	55
Cellular plasticity and immune microenvironment of malignant pleural effusion are associated with EGFR-TKI resistance in non–small-cell lung carcinoma	54
Idealized analysis of relative values of bidirectional versus unidirectional electric vehicle charging in deeply decarbonized electricity systems	54
Exploring drought-responsive crucial genes in Sorghum	54
Bacterial lipopolysaccharides can initiate regeneration of the Xenopus tadpole tail	54
Dynamics of base pairs with low stability in RNA by solid-state nuclear magnetic resonance exchange spectroscopy	54
Network characterization linc1393 in the maintenance of pluripotency provides the principles for lncRNA targets prediction	53
Integrated edge information and pathway topology for drug-disease associations	53
Neuronal-enriched small extracellular vesicles trigger a PD-L1-mediated broad suppression of T cells in Parkinson’s disease	53
Salivary gland cancer organoids are valid for preclinical genotype-oriented medical precision trials	52
Prefrontal cortex encodes value pop-out in visual search	52
A limitation map of performance for porous electrodes in lithium-ion batteries	52
Mapping structural variations in Haemaphysalis longicornis and Rhipicephalus microplus reveals vector-pathogen adaptation	51
Adsorption and desorption behavior of Zn2+ in a flow-through electrosorption reactor	51
Cellular resistance to an oncolytic virus is driven by chronic activation of innate immunity	51
T cells with increased responsiveness cause obesity in mice without diet intervention	50
Iterative multiscale and multi-physics computations for operando catalyst nanostructure elucidation and kinetic modeling	50
The role of chirality and plastic crystallinity in the optical and mechanical properties of chlorosomes	50
Low levels of CIITA and high levels of SOCS1 predict COVID-19 disease severity in children and adults	50
Diverse bacteriophages for biocontrol of ESBL- and AmpC-β-lactamase-producing E. coli	50
Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling	49
Trash-to-fuel: Converting municipal waste into transportation fuels by pyrolysis	49
Spi1 R235C point mutation confers hypersensitivity to radiation-induced acute myeloid leukemia in mice	49
Sediment provenance of Late Carboniferous-Early Triassic in the Puyang area, Eastern North China Craton	49
Antithrombogenic polysaccharide coatings to improve hemocompatibility, protein-repellence, and endothelial cell response	49
Zinc finger protein 593 promotes breast cancer development by ensuring DNA damage repair and cell-cycle progression	48
Unsupervised attribute reduction based on variable precision weighted neighborhood dependency	48
Combinatorial drug screening on 3D Ewing sarcoma spheroids using droplet-based microfluidics	48
Genomic evidence of symbiotic adaptations in fungus-associated bacteria	48
Preparation of WSi@SiOx/Ti3C2 from photovoltaic silicon waste as high-performance anode materials for lithium-ion batteries	48
Machine learning unveils immune-related signature in multicenter glioma studies	48
Amitriptyline revitalizes ICB response via dually inhibiting Kyn/Indole and 5-HT pathways of tryptophan metabolism in ovarian cancer	48
Condensation of water vapor from humid air inside vertical channels formed by flat plates	48
LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis	48
Inspired by struggle: A personal journey to global precision brain health	47
How many markers are needed to robustly determine a cell's type?	47
MOCSS: Multi-omics data clustering and cancer subtyping via shared and specific representation learning	47
Oxytocin promotes social proximity and decreases vigilance in groups of African lions	47

Global burden of head and neck cancers from 1990 to 2019	47
CD168+ macrophages promote hepatocellular carcinoma tumor stemness and progression through TOP2A/β-catenin/YAP1 axis	47
Inflammation conditional genome editing mediated by the CRISPR-Cas9 system	47
SENP2-based N-terminal truncation of α-synuclein in Lewy pathology propagation	46
Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA mimicry and histone chaperone efficiency	46
ENTPD8 overexpression enhances anti-PD-L1 therapy in hepatocellular carcinoma via miR-214-5p inhibition	46
Clathrin-mediated endocytosis cooperates with bulk endocytosis to generate vesicles	45
Nanozyme-based wearable biosensors for application in healthcare	45
An SI-traceable reference material for virus-like particles	45
Some dogs can find the payoff-dominant outcome in the Assurance game	45
Audition controls the flow of visual time during multisensory perception	45
Nuclear talin-1 provides a bridge between cell adhesion and gene expression	45
Differences in biomarker levels and proteomic survival prediction across two COVID-19 cohorts with distinct treatments	45
Molecular simulations reveal intricate coupling between agonist-bound β-adrenergic receptors and G protein	45
WIPF1 promotes gastric cancer progression by regulating PI3K/Akt signaling in a myocardin-dependent manner	45
Classification of polyphenol oxidases shows ancient gene duplication leading to two distinct enzyme types	45
Native T1 mapping-based radiomics diagnosis of kidney function and renal fibrosis in chronic kidney disease	44
Vimentin is an important ACE2 co-receptor for SARS-CoV-2 in epithelial cells	44
Genome editing is induced in a binary manner in single human cells	44
Temporal dynamics of the soil bacterial community following Bacillus invasion	44
Dose-dependent association between physical activity and mental health, and mitigation effects on risk behaviors	44
Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes	44
Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response	44
Heterostructured CoO/MoB MBene composites for high performance lithium-ion batteries anode	43
A network-based approach reveals the dysregulated transcriptional regulation in non-alcoholic fatty liver disease	43
Architecture inspired structure engineering toward carbon nanotube hybrid for microwave absorption promotion	43
A fast method to distinguish between fermentative and respiratory metabolisms in single yeast cells	43
Decline in stability of forest productivity in the tropics as determined by canopy water content	43
Hydroxyapatite catalyzed hydrothermal liquefaction transforms food waste from an environmental liability to renewable fuel	43
YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia	43
Understanding COVID-19 progression with longitudinal peripheral blood mononuclear cell proteomics: Changes in the cellular proteome over time	42
Origin, heterogeneity, and interconversion of noncanonical bistable switches from the positive feedback loops under dual signaling	42
Design and validation of depth camera-based static posture assessment system	42
Chemical inhibition of phosphatidylcholine biogenesis reveals its role in mitochondrial division	42
Transchromosomic bovine-derived anti-SARS-CoV-2 polyclonal human antibodies protects hACE2 transgenic hamsters against multiple variants	42
Metabolic stratification of human breast tumors reveal subtypes of clinical and therapeutic relevance	42
CRISPRe: An innate transcriptional enhancer for endogenous genes in CRISPR-Cas immunity	42
Semen promotes oocyte development in Sebastes schlegelii elucidating ovarian development dynamics in live-bearing fish	42
Distance-weighted Sinkhorn loss for Alzheimer’s disease classification	42
Inhibitory temporo-parietal effective connectivity is associated with explicit memory performance in older adults	42
Short-term auditory priming in freely-moving mice	42
Thermal acclimation uncovers a simple genetic basis of adaptation to high temperature in a cosmopolitan pest	42
Gradient phase and amplitude errors in atomic magnetic gradiometers for biomagnetic imaging systems	42
Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus	42
Merits of dietary patterns for China’s future food security satisfying socioeconomic development and climate change adaptation	41
The roles of lncMALAT1 in coronary artery disease regulation and therapeutic perspective: A systematic review	41
Evolution of zygomycete secretomes and the origins of terrestrial fungal ecologies	41
Large-scale and cost-efficient agrivoltaics system by spectral separation	41
Replication fork blocking deficiency leads to a reduction of rDNA copy number in budding yeast	41
The transcription factor IRF4 regulates the homeostasis and function of intestinal ILC3s	41
Comparative tissue proteomics reveals unique action mechanisms of vaccine adjuvants	41
Atherosclerotic plaque vulnerability quantification system for clinical and biological interpretability	41
Histatin 1-modified SIS hydrogels enhance the sealing of peri-implant mucosa to prevent peri-implantitis	41
Changing the spin disorder of two-dimensional magnetic Cr2TiC2Tx to long-range order through noble metal adhesion	41
Do not compromise: Nurse honeybees practice strict protein-lipid regulation	41
Processing visual ambiguity in fractal patterns: Pareidolia as a sign of creativity	41
The implication of integrative multiple RNA modification-based subtypes in gastric cancer immunotherapy and prognosis	41
Thermal conductivity across transition metal dichalcogenide bilayers	41
β-hydroxybutyrate recapitulates the beneficial effects of ketogenic metabolic therapy in polycystic kidney disease	40
Seasonal Shifts in Pan-Arctic Ocean Downward Radiation and Key Drivers	40
Sverdrup-Henson crater: A candidate location for the first lunar South Pole settlement	40
Microbial diversity in mountain-dwelling amphibians: The combined effects of host and climatic factors	40
Smiling underwater: Exploring playful signals and rapid mimicry in bottlenose dolphins	40
Red blood cell flickering activity locally controlled by holographic optical tweezers	40
Antimicrobial peptide LL37 and regulatory T cell associated with late-onset sepsis in very preterm infants	40
Lasso peptides sviceucin and siamycin I exhibit anti-virulence activity and restore vancomycin effectiveness in vancomycin-resistant pathogens	40
Uncovering the impact and mechanisms of air pollution on eye and ear health in China	40
DUSP6 deletion protects mice and reduces disease severity in autoimmune arthritis	40
DDX56 promotes EMT and cancer stemness via MELK-FOXM1 axis in hepatocellular carcinoma	40
Microglia-containing cerebral organoids derived from induced pluripotent stem cells for the study of neurological diseases	40
TMS-EEG and resting-state EEG applied to altered states of consciousness: oscillations, complexity, and phenomenology	40
Integrative analysis of multimodal patient data identifies personalized predictors of tuberculosis treatment prognosis	40
High-throughput screening identifies broad-spectrum Coronavirus entry inhibitors	40
IRP1 mediated ferroptosis reverses temozolomide resistance in glioblastoma via affecting LCN2/FPN1 signaling axis depended on NFKB2	40
RNA editing in host lncRNAs as potential modulator in SARS-CoV-2 variants-host immune response dynamics	40
Identification of optimal conditions for human placental explant culture and extracellular vesicle release	39
An NLP-based technique to extract meaningful features from drug SMILES	39
Postnatal hyperglycemia alters amino acid profile in retinas (model of Phase I ROP)	39
Type I interferon regulation by USP18 is a key vulnerability in cancer	39
Profiling ovarian cancer tumor and microenvironment during disease progression for cell-based immunotherapy design	39
Tendon-inspired anti-freezing tough gels	39
Glucose promotes regulatory T cell differentiation to maintain intestinal homeostasis	39
RNA modification-related genes illuminate prognostic signature and mechanism in esophageal squamous cell carcinoma	39
RAD21 deficiency drives corneal to scleral differentiation fate switching via upregulating WNT9B	39
Quantitative analysis of asynchronous transcription-translation and transcription processivity in Bacillus subtilis under various growth conditions	39
Long non-coding RNA MIAT is involved in the regulation of pyroptosis in diabetic cardiomyopathy via targeting miR-214-3p	39
Florigen and antiflorigen gene expression correlates with reproductive state in a marine angiosperm, Zostera marina	38
MUC1-C integrates aerobic glycolysis with suppression of oxidative phosphorylation in triple-negative breast cancer stem cells	38
Sound effects on body perception vary with the social support network of individuals	38
Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis	38
HDAC1/2 inhibitor therapy improves multiple organ systems in aged mice	38
Interferon-α and thymosin-α1 plus tislelizumab enhance CD8+ T cell cytotoxicity toward pancreatic ductal adenocarcinoma	38
Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia	38
Schwann cells contribute to demyelinating diabetic neuropathy and nerve terminal structures in white adipose tissue	37
Genome-wide mRNA profiling in urinary extracellular vesicles reveals stress gene signature for diabetic kidney disease	37