iScience

Article	Citations
Emerging collaborations at the forefront of growth in electrochemical synthesis	392
Improved interpretation of 18F-florzolotau PET in progressive supranuclear palsy using a normalization-free deep-learning classifier	342
Cambrian comb jellies from Utah illuminate the early evolution of nervous and sensory systems in ctenophores	185
Integrative metabolomic and proteomic signatures define clinical outcomes in severe COVID-19	184
Longitudinal monitoring of individual infection progression in Drosophila melanogaster	170
All-optical interrogation of brain-wide activity in freely swimming larval zebrafish	166
A network-based computational and experimental framework for repurposing compounds toward the treatment of non-alcoholic fatty liver disease	166
Transcriptome analysis of human hypertrophic cardiomyopathy reveals inhibited cardiac development pathways in children	151
The severity of dry and hot climate extremes and their related impacts on vegetation in Madagascar	141
IL-15 boosts activated HBV core-specific CD8+ progenitor cells via metabolic rebalancing in persistent HBV infection	140
Some dogs can find the payoff-dominant outcome in the Assurance game	139
Experimental prognostic model integrating N6-methyladenosine-related programmed cell death genes in colorectal cancer	134
A fast method to distinguish between fermentative and respiratory metabolisms in single yeast cells	133
Designing clinical trials for patients who are not average	126
Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet	125
Crosstalk between chromatin and Shavenbaby defines transcriptional output along the Drosophila intestinal stem cell lineage	121
Prioritize carbon pricing over fossil-fuel subsidy reform	112
Regulatory network in heat stress response in parasitoid wasp focusing on Xap5 heat stress regulator	110
Two distinct modes of action of molecular glues in the plant hormone co-receptor COI1-JAZ system	110
Intracellular Ca2+ oscillation frequency and amplitude modulation mediate epithelial apical and basolateral membranes crosstalk	107
A mitochondria-targeting dihydroartemisinin derivative as a reactive oxygen species -based immunogenic cell death inducer	103
Optical modulation of cell nucleus penetration and singlet oxygen release of a switchable platinum complex	100
Cooperative breeding alters physiological and behavioral responses to habitat fragmentation	97
MIF modulates p38/ERK phosphorylation via MKP-1 induction in sarcoidosis	96
Deep molecular learning of transcriptional control of a synthetic CRE enhancer and its variants	96

Large area fractional laser treatment of mouse skin increases energy expenditure	96
A rapid isothermal CRISPR-Cas13a diagnostic test for genital herpes simplex virus infection	95
From TgO/GABA-AT, GABA, and T-263 Mutant to Conception of Toxoplasma	95
Hidden features of NAD-RNA epitranscriptome in Drosophila life cycle	94
The emergence of the multisensory brain: From the womb to the first steps	93
Characterizing adjuvants’ effects at murine immunoglobulin repertoire level	92
Illumination by short-wavelength light inside the blind spot decreases light detectability	91
W-Net: A boundary-aware cascade network for robust and accurate optic disc segmentation	91
Lactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia	89
Complex sphingolipid profiling and identification of an inositol-phosphorylceramide synthase in Dictyostelium discoideum	89
HDAC1 and HDAC2 orchestrate Wnt signaling to regulate neural progenitor transition during brain development	89
Post-translational modifications of pyruvate dehydrogenase complex in cardiovascular disease	89
BDNF-dependent nano-organization of Neogenin and the WAVE regulatory complex promotes actin remodeling in dendritic spines	86
Crosstalk between 6-methyladenine and 4-methylcytosine in Geobacter sulfurreducens exposed to extremely low-frequency electromagnetic field	84
Naive primary neutrophils play a dual role in the tumor microenvironment	84
A nested model for AI design and validation	84
GRP94 promotes anoikis resistance and peritoneal metastasis through YAP/TEAD1 pathway in gastric cancer	83
Endocrine gland size is proportional to its target tissue size	82
Blood cell traits and venous thromboembolism in East Asians: Observational and genetic evidence	80
Knockouts of CYP51A1, DHCR24, or SC5D from cholesterol synthesis reveal pathways modulated by sterol intermediates	80
Long-term results of allogenic corneal lenticule of hyperopic SMILE for post-LASIK ectasia	80
Epidemiology of herpes simplex virus type 1 in the United States: Systematic review, meta-analyses, and meta-regressions	80
Spastin regulates ER-mitochondrial contact sites and mitochondrial homeostasis	79
Genome of the most noxious weed water hyacinth (Eichhornia crassipes) provides insights into plant invasiveness and its translational potential	78
Uncovering the impact and mechanisms of air pollution on eye and ear health in China	78
Longitudinal cohort study highlights cancer-preventive benefits of lipid-lowering drugs	78
Pushing the limits of ultrafast diffraction: Imaging quantum coherences in isolated molecules	77
Immunogenicity of a third dose with mRNA-vaccines in the ChAdOx1-S/BNT162b2 vaccination regimen against SARS-CoV-2 variants	76
Lipids from a snail host regulate the multicellular behavior of a predator of parasitic schistosomes	75
Face privacy protection scheme by security-enhanced encryption structure and nonlinear dynamics	75
The mitochondrial stress signaling tunes immunity from a view of systemic tumor microenvironment and ecosystem	75
Computational modeling of mast cell tryptase family informs selective inhibitor development	75
Improving cardiovascular risk stratification through multivariate time-series analysis of cardiopulmonary exercise test data	74
Positional information modulates transient regeneration-activated cell states during vertebrate appendage regeneration	73
A safe method for rapid therapeutic pancreatic cooling	73
Combined climate change and dispersal capacity positively affect Hoplobatrachus chinensis occupancy of agricultural wetlands	73
β-hydroxybutyrate recapitulates the beneficial effects of ketogenic metabolic therapy in polycystic kidney disease	72
A global transcriptional atlas of the effect of acute sleep deprivation in the mouse frontal cortex	72
Diffusion of activated ATM explains γH2AX and MDC1 spread beyond the DNA damage site	71
Chronic disease incidence explained by stepwise models and co-occurrence among them	70
Optically induced quantum transitions in direct probed mesoscopic NbSe2 for prototypical bolometers	69
Stenotrophomonas maltophilia provokes NEU1-mediated release of a flagellin-binding decoy receptor that protects against lethal infection	69
Validation of a PD-1/CD28 chimeric switch receptor to augment CAR-T function in dogs with spontaneous B cell lymphoma	69
The branched receptor-binding complex of Ackermannviridae phages promotes adaptive host recognition	68
Feature matching based on local windows aggregation	68
NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes	67
Unveiling differential gene co-expression networks and its effects on levodopa-induced dyskinesia	67
PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation	67
Crosstalk between butyrate oxidation in colonocyte and butyrate-producing bacteria	67
A TDV attention-based BiGRU network for AIS-based vessel trajectory prediction	66

A generalized non-linear model predicting efficacy of neoadjuvant therapy in HER2+ breast cancer	66
Error monitoring when no errors are possible: Arbitrary free-choice decisions invoke error monitoring processes	66
Information integration for decision-making in desert locusts	66
Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity	66
Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes	65
Ultra-rare complement factor 8 coding variants in families with age-related macular degeneration	65
Endogenous IFITMs boost SARS-coronavirus 1 and 2 replication whereas overexpression inhibits infection by relocalizing ACE2	65
Sound categorization by crocodilians	64
Association of branched-chain amino acids with mortality-the Ludwigshafen Risk and Cardiovascular Health (LURIC) study	64
Thermal conductivity across transition metal dichalcogenide bilayers	64
Premature termination of transcription is shaped by Rho and translated uORFS in Mycobacterium tuberculosis	63
Neurosensory anatomy and function in Dimetrodon, the first terrestrial apex predator	63
Construction of a national natural hazard interaction framework: The case of Sweden	62
Adipocyte-derived chemerin rescues lipid overload-induced cardiac dysfunction	62
Systematic fine-mapping and functional studies of prostate cancer risk variants	62
Semi-supervised analysis of myeloid and T cell behavior in ex vivo ovarian tumor slices reveals changes in cell motility after treatments	61
Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models	61
Poplar coma morphogenesis and miRNA regulatory networks by combining ovary tissue sectioning and deep sequencing	61
Transcriptomic investigation reveals a physiological mechanism for Beauveria bassiana to survive under linoleic acid stress	61
Turing-pattern model of scaffolding proteins that establish spatial asymmetry during the cell cycle of Caulobacter crescentus	61
Reiterated male-to-female violence disrupts hippocampal estrogen receptor β expression, prompting anxiety-like behavior	60
Comprehensive analysis of bZIP transcription factors in passion fruit	60
General anesthetic action profile on the human prefrontal cortex cells through comprehensive single-cell RNA-seq analysis	60
PanKA: Leveraging population pangenome to predict antibiotic resistance	59
Enhancing corrosion resistance of biodegradable magnesium with dicalcium phosphate dihydrate and Chlorella sp. biomass	59
Molecular basis of pigment structural diversity in echinoderms	58
Highly compromised auditory spatial perception in aided congenitally hearing-impaired and rapid improvement with tactile technology	58
HDAC1/2 inhibitor therapy improves multiple organ systems in aged mice	57
Proteasome assembly chaperone translation upon stress requires Ede1 phase separation at the plasma membrane	57
Epigenetic and transcriptional responses in circulating leukocytes are associated with future decompensation during SARS-CoV-2 infection	56
Development and validation of a semi-supervised deep learning model for automatic retinopathy of prematurity staging	56
Overexpression and knockdown of cotton GhdadD gene reveals its drought and salt stress tolerance role	56
Riboproteome remodeling during quiescence exit in Saccharomyces cerevisiae	56
Therapy-induced normal tissue damage promotes breast cancer metastasis	56
Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus	55
The spatiotemporal pattern of glypican coordinates primordial germ cell differentiation with ovary development	55
Targeting abatacept-resistant T-helper-17 cells by aldehyde dehydrogenase inhibition	55
Mechanistic insights into CDCP1 clustering on non-small-cell lung cancer membranes revealed by super-resolution fluorescent imaging	55
Kremen1 regulates the regenerative capacity of support cells and mechanosensory hair cells in the zebrafish lateral line	55
A crack compensation strategy for highly stretchable conductors based on liquid metal inclusions	55
A novel APA-based prognostic signature may predict the prognosis of lung adenocarcinoma in an East Asian population	54
Genetic overlap for ten cardiovascular diseases: A comprehensive gene-centric pleiotropic association analysis and Mendelian randomization study	54
Super-resolution microscopy reveals the nanoscale cluster architecture of the DEK protein cancer biomarker	54
Multi-platform-based characterization of ferroptosis in human colorectal cancer	54
Abundant nitrogenous secondary organic aerosol formation accelerated by cloud processing	53
Shigella OspC3 suppresses murine cytosolic LPS sensing	53
Inaccessible time to visual awareness during attentional blinks in macaques and humans	53
Making solar electricity dispatchable: A technical and economic assessment of the main conversion and storage technologies	53
Beyond radiologist-level liver lesion detection on multi-phase contrast-enhanced CT images by deep learning	53
Ancestral SARS-CoV-2 immune imprinting persists on RBD but not NTD after sequential Omicron infections	52
Magnitude of cancer-associated thrombosis in Africa: A systematic review and meta-analysis	52
Quantum and complex-valued hybrid networks for multi-principal element alloys phase prediction	52
The attraction effect of cleaning air on migrants in China: A comparative analysis with the contribution of wage and house prices	52
Gene expression dynamics in fibroblasts during early-stage murine pancreatic carcinogenesis	52
Transcriptomic and proteomic analysis reveals the mechanism of chicken cecum response to Salmonella enterica serovar Enteritidis inoculation	52
Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism	52
Neonatal infection with Bordetella pertussis promotes autism-like phenotypes in mice	52
Predicting phage-host interaction via hyperbolic Poincaré graph embedding and large-scale protein language technique	51
Dual opposing quadrature-PT symmetry	51
Bioprinting approaches in cardiac tissue engineering to reproduce blood-pumping heart function	51
Profiling signaling mediators for cell-cell interactions and communications with microfluidics-based single-cell analysis tools	51
Abundant repressor binding sites in human enhancers are associated with the fine-tuning of gene regulation	51
Environmental tipping points for global soil nitrogen-fixing microorganisms	51
Microsaccade selectivity as discriminative feature for object decoding	51
Analysis of cellular NO-GC expression in the murine heart and lineage determination in angiotensin II-induced fibrosis	51
Advances in nanoparticle-based radiotherapy for cancer treatment	51
Lysosomal activity in response to the incubation of pristine and functionalized carbon nanodots	50
Penfluridol targets septin7 to suppress endometrial cancer by septin7-Orai/IP3R-Ca2+-PIK3CA pathway	50
A critical review of heat pump adoption in empirical and modeling literature	50
TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination	50
Hyperglycemic milieu impairs Vγ9Vδ2 T cell functions in tuberculosis patients and prolongs M.tb negative conversion time	50
Sensitivity of future regional and global energy markets and macroeconomic activity to a hypothetical global energy market disruption	50
Global functional genomics reveals GRK5 as a cystic fibrosis therapeutic target synergistic with current modulators	49
Episodic rhythmicity is generated by a distributed neural network in the developing mammalian spinal cord	49
Predicting tuberculosis drug efficacy in preclinical and clinical models from in vitro data	49
Robustness of machine learning predictions for Fe-Co-Ni alloys prepared by various synthesis methods	49
Tau and MAP6 establish labile and stable domains on microtubules	49
The superconductivity and electron-doping effect in MgP2H14 hydrides	49
Electrolytic hydrogen production; how green must green be?	48
Release of extracellular DNA by Pseudomonas sp. as a major determinant for biofilm switching and an early indicator for cell population control	48

Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models	48
Chemotaxis of Drosophila border cells is modulated by tissue geometry through dispersion of chemoattractants	48
Enhancing malignant transformation predictions in oral potentially malignant disorders: A novel machine learning framework using real-world data	48
Retraction Notice to: LIN28 and histone H3K4 methylase induce TLR4 to generate tumor-initiating stem-like cells	48
Lasso peptides sviceucin and siamycin I exhibit anti-virulence activity and restore vancomycin effectiveness in vancomycin-resistant pathogens	48
Predictable sequential structure augments auditory sensitivity at threshold	47
TAF7 directly targets SAA1 to enhance triple-negative breast cancer metastasis via phosphorylating E-cadherin and N-cadherin	47
Differences in biomarker levels and proteomic survival prediction across two COVID-19 cohorts with distinct treatments	47
The impact of climatic factors on negative sentiments: An analysis of human expressions from X platform in Germany	47
Would widespread adoption of third-generation nuclear power HPR1000 enhance the mitigation of net greenhouse gas emissions?	47
Central GABAergic neuromodulation of nocifensive behaviors in bumble bees	46
A microfluidic platform for anterior-posterior human endoderm patterning via countervailing morphogen gradients in vitro	46
Gasdermin D-dependent neutrophil extracellular traps exacerbate cytokine storm contributing to pyoderma gangrenosum pathogenesis	46
Compositional variation in eye-infiltrating immune cells distinguishes human uveitis subtypes	46
Forced intracellular degradation of xenoantigens as a modality for cell-based cancer immunotherapy	46
Targeting insulin-like growth factor 1 receptor restricts development and severity of secondary lymphedema in mice	46
Spatiotemporal profiling of protein kinase A activity in spontaneously beating hiPSC-derived cardiac organoids	46
Synthetic liver fibrotic niche extracts achieve in vitro hepatoblasts phenotype enhancement and expansion	45
New directions in mapping the Earth’s surface with citizen science and generative AI	45
Utility disconnection protections and the incidence of energy insecurity in the United States	45
The genus Limnospira contains only two species, both unable to produce microcystins: L. maxima and L. platensis	45
Deep learning enables stochastic optical reconstruction microscopy-like superresolution image reconstruction from conventional microscopy	45
A tetracationic porphyrin with dual anti-prion activity	45
Cell surface heparan sulfate is an attachment receptor for grass carp reovirus	45
Skeletal muscle proteomes reveal downregulation of mitochondrial proteins in transition from prediabetes into type 2 diabetes	45
Patent bibliometric analysis for global trend of organoid technologies in the past decade	44
Near-field radiative heat transfer between topological insulators via surface plasmon polaritons	44
A geometric framework for understanding dynamic information integration in context-dependent computation	44
Oncolytic alphavirus replicons mediated recruitment and activation of T cells	44
Iterative multiscale and multi-physics computations for operando catalyst nanostructure elucidation and kinetic modeling	44
p73-regulated FER1L4 lncRNA sponges the oncogenic potential of miR-1273g-3p and aids in the suppression of colorectal cancer metastasis	44
A machine learning model to investigate factors contributing to the energy transition of utility and independent power producer sectors internationally	44
DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in in vitro and in vivo models of Huntington disease	43
Copper-catalyzed oxidative dehydrogenative dearomatization of indole derivatives: A new strategy to construct spirocyclic indolenines	43
The spatiotemporal extent of the Green Sahara during the last glacial period	43
Prolonged norovirus infections correlate to quasispecies evolution resulting in structural changes of surface-exposed epitopes	43
Loss of miR-29a impairs decidualization of endometrial stromal cells by TET3 mediated demethylation of Col1A1 promoter	43
DNA methylation-based profiling of horse archaeological remains for age-at-death and castration	43
Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development	43
MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism	43
Corticosterone antagonist or TrkB agonist attenuates schizophrenia-like behavior in a mouse model combining Bdnf-e6 deficiency and developmental stress	43
Oxytocin promotes social proximity and decreases vigilance in groups of African lions	43
Rickettsial pathogen inhibits tick cell death through tryptophan metabolite mediated activation of p38 MAP kinase	43
First-principles calculations of hematite (α-Fe2O3) by self-consistent DFT+U+V	43
Combinatorial drug screening on 3D Ewing sarcoma spheroids using droplet-based microfluidics	43
Host ZCCHC3 blocks HIV-1 infection and production through a dual mechanism	43
Introduction of Aedes aegypti mosquitoes carrying wAlbB Wolbachia sharply decreases dengue incidence in disease hotspots	42
Regeneration of interfacial bonding force of waste carbon fibers by light: Process demonstration and atomic level analysis	42
Cancer cell – Fibroblast crosstalk via HB-EGF, EGFR, and MAPK signaling promotes the expression of macrophage chemo-attractants in squamous cell carcinoma	42
Molecular convergence and transgenic evidence suggest a single origin of laryngeal echolocation in bats	42
An epigenetic signature of advanced colorectal cancer metastasis	42
Functional organization of the maternal and paternal human 4D Nucleome	42
Photothermal conversion of Ti2O3 film for tuning terahertz waves	42
Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery	42
Design principles and therapeutic applications of novel synthetic WNT signaling agonists	41
3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects	41
Non-invasive PET imaging of liver fibrogenesis using a RESCA-conjugated Affibody molecule	41
Weighted cue integration for straight-line orientation	41
YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring	41
The secretome of Agaricus bisporus: Temporal dynamics of plant polysaccharides and lignin degradation	40
Synthesis of versatile neuromodulatory molecules by a gut microbial glutamate decarboxylase	40
The Caenorhabditis elegans neuronal GPCR OCTR-1 modulates longevity responses to both warm and cold temperatures	40
SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury	40
Proteomic insights into the environmental adaptation of the subtropical brain coral host Platygyra carnosa	40
Towards a roadmap for space-based observations of the land sector for the UNFCCC global stocktake	40
Genomic evidence of symbiotic adaptations in fungus-associated bacteria	40
Efficient proximal tubule-on-chip model from hiPSC-derived kidney organoids for functional analysis of renal transporters	40
Evolution of zygomycete secretomes and the origins of terrestrial fungal ecologies	39
Multimodal imaging of the dynamic brain tumor microenvironment during glioblastoma progression and in response to treatment	39
WITHDRAWN: Fibromodulin alleviates matrix stiffness-induced degeneration of the nucleus pulposus by regulating cytoskeleton and autophagy	39
Retraction Notice to: Application of Inorganic Nanocomposite Hydrogels in Bone Tissue Engineering	39
Topographic representation of visually evoked emotional experiences in the human cerebral cortex	39
From pseudo to real-time dynamics of T cell thymic differentiation	39
Spi1 R235C point mutation confers hypersensitivity to radiation-induced acute myeloid leukemia in mice	39
Mitigating climate change to alleviate economic inequality under the Paris Agreement	39
GwAAP: A genome-wide amino acid coding-decoding quantitative proteomics system	39
Atherosclerotic plaque vulnerability quantification system for clinical and biological interpretability	39
Involvement of neuronal tachykinin-like receptor at 86C in Drosophila disc repair via regulation of kynurenine metabolism	39
MIF-like domain containing protein orchestrates cellular differentiation and virulence in the fungal pathogen Magnaporthe oryzae	38
PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity	38
A facile spray-pressing synthesis approach for reusable photothermal masks	38
DHHC2 regulates fear memory formation, LTP, and AKAP150 signaling in the hippocampus	38
Unraveling the regulation of sugar beet pulp utilization in the industrially relevant fungus Aspergillus niger	38
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes	38
In vivo spontaneous activity and coital-evoked inhibition of mouse accessory olfactory bulb output neurons	38
Leishmania mexicana centrin knockout parasites promote M1-polarizing metabolic changes	38
Dynamics of base pairs with low stability in RNA by solid-state nuclear magnetic resonance exchange spectroscopy	38
Anhydrobiotic chironomid larval motion-based multi-sensing microdevice for the exploration of survivable locations	37
Free-standing conductive nickel metal-organic framework nanowires as bifunctional electrodes for wearable pressure sensors and Ni-Zn batteries	37
Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases	37
Clathrin-mediated endocytosis cooperates with bulk endocytosis to generate vesicles	37
Murine double minute 2 aggravates adipose tissue dysfunction through ubiquitin-mediated six-transmembrane epithelial antigen of prostate 4 degradation	37
Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model	37
The attitudinal space framework: Embracing the multidimensionality of attitudinal diversity	37
Controlling neural territory patterning from pluripotency using a systems developmental biology approach	37