OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Pharmaceutics-X is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Multifunctional Bi2S3-Au nanoclusters for fluorescence/infrared thermal imaging guided photothermal therapy	56
Study on the preparation of stabilizer-free silymarin nanocrystals and its oral absorption mechanisms	24
Development of cancer-associated fibroblasts-targeting polymeric nanoparticles loaded with 8-O-methylfusarubin for breast cancer treatment	17
Investigating the effect of whey and casein proteins on drug solubility from a paediatric drug absorption perspective	16
Exploiting recent trends for the synthesis and surface functionalization of mesoporous silica nanoparticles towards biomedical applications	14
Preparation of atorvastatin calcium-loaded liposomes using thin-film hydration and coaxial micromixing methods: A comparative study	14
Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings	11
Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel	11
Editorial Board	10
Efficient ocular delivery of siRNA via pH-sensitive vehicles for corneal neovascularization inhibition	10
Towards a better understanding of thermally treated polycarbophil matrix tablets for controlled release	10
Tailored ASD destabilization - Balancing shelf life stability and dissolution performance with hydroxypropyl cellulose	9
Exploring high-throughput synchrotron X-Ray powder diffraction for the structural analysis of pharmaceuticals	9
Effect of treatment with original or biosimilar adalimumab on SARS-CoV2 vaccination antibody titers	9
Releasing fast and slow: Non-destructive prediction of density and drug release from SLS 3D printed tablets using NIR spectroscopy	8
Drug crystal growth in ternary amorphous solid dispersions: Effect of surfactants and polymeric matrix-carriers	8
Oral etoposide and zosuquidar bioavailability in rats: Effect of co-administration and in vitro-in vivo correlation of P-glycoprotein inhibition	7
Design and validation of a custom-made system to measure transepithelial electrical impedance in human corneas preserved in active storage machine	7
The use of X-ray microtomography to investigate the microstructure of pharmaceutical tablets: Potentials and comparison to common physical methods	7
Rationalized landscape on protein-based cancer nanomedicine: Recent progress and challenges	7
Feed factor profile prediction model for two-component mixed powder in the twin-screw feeder	7
Impact of mucus modulation by N-acetylcysteine on nanoparticle toxicity	6
Editorial board	6
Drop-on-powder 3D printing of amorphous high dose oral dosage forms: Process development, opportunities and printing limitations	6
The interplay of poorly soluble drugs in dissolution from amorphous solid dispersions	6

Accelerating 3D printing of pharmaceutical products using machine learning	6
Stimuli-sensitive biomimetic nanoparticles for the inhibition of breast cancer recurrence and pulmonary metastasis	6
Identification of novel cyanoacrylate monomers for use in nanoparticle drug delivery systems prepared by miniemulsion polymerisation – A multistep screening approach	6
From design to 3D printing: A proof-of-concept study for multiple unit particle systems (MUPS) printed by dual extrusion fused filament fabrication	5
Additive manufacturing technologies with emphasis on stereolithography 3D printing in pharmaceutical and medical applications: A review	5
Fabrication and application of targeted ciprofloxacin nanocarriers for the treatment of chronic bacterial prostatitis	5
Design of an innovative nanovehicle to enhance brain permeability of a novel 5-HT6 receptor antagonist	5
Long term behavior of dexamethasone-loaded cochlear implants: In vitro & in vivo	5
Everolimus-encapsulation in Pluronic P123 self-assembled micelles as drug delivery systems for drug-coated balloons	5
Evaluating a targeted Palbociclib-Trastuzumab loaded smart niosome platform for treating HER2 positive breast cancer cells	5
Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations	5
Colon targeting in rats, dogs and IBD patients with species-independent film coatings	5
RETRACTED: Development of thermosensitive hydrogel of Amphotericin-B and Lactoferrin combination-loaded PLGA-PEG-PEI nanoparticles for potential eradication of ocular fungal infections: In-vitro, ex-v	4
Ultrasound-targeted sirolimus-loaded microbubbles improves acute rejection of heart transplantation in rats by inhibiting TGF-β1-Smad signaling pathway, promoting autophagy and reducing inflammation	4
Aptamer-based nanotrains and nanoflowers as quinine delivery systems	4
Investigation on the use of fused deposition modeling for the production of IR dosage forms containing Timapiprant	4
Prodigiosin hydrogel to promote healing of trauma-infected multidrug-resistant Staphylococcus aureus mice wounds	4
A simple nanoplatform of thermo-sensitive liposomes and gold nanorods to treat bone metastasis through improved chemotherapy combined with photothermal therapy	4
Phase homogeneity in ternary amorphous solid dispersions and its impact on solubility, dissolution and supersaturation – Influence of processing and hydroxypropyl cellulose grade	4
Erratum regarding missing Conflict of Interest statements in previously published articles	4
Enhancing oocyte in vitro maturation and quality by melatonin/bilirubin cationic nanoparticles: A promising strategy for assisted reproduction techniques	4
A drug repurposing approach of Atorvastatin calcium for its antiproliferative activity for effective treatment of breast cancer: In vitro and in vivo assessment	4
Characterization of radicals in polysorbate 80 using electron paramagnetic resonance (EPR) spectroscopy and spin trapping	4
Polydopamine-activated celastrol carbon dots for synergistic chemotherapy-photothermal therapy of tumors	3
The effect of excipient particle size on the reduction of compactibility after roller compaction	3
Editorial board	3
Experimental determination of the velocity distribution in USP Apparatus 1 (basket apparatus) using Particle Image Velocimetry (PIV)	3
Nanostructured N/S doped carbon dots/mesoporous silica nanoparticles and PVA composite hydrogel fabrication for anti-microbial and anti-biofilm application	3
Influence of high pressure compaction on solubility and intrinsic dissolution of ibuprofen binary mixtures employing standard excipients	3
Formulating a heat- and shear-labile drug in an amorphous solid dispersion: Balancing drug degradation and crystallinity	3
Anti-inflammatory effects of acacia and guar gum in 5-amino salicylic acid formulations in experimental colitis	3
Classification of scanning electron microscope images of pharmaceutical excipients using deep convolutional neural networks with transfer learning	3
Dexamethasone-loaded cochlear implants: How to provide a desired “burst release”	3
Tailored hyaluronic acid-based nanogels as theranostic boron delivery systems for boron neutron cancer therapy	3
Quantitative comparison of the protein corona of nanoparticles with different matrices	3
Atorvastatin-loaded emulsomes foam as a topical antifungal formulation	3
In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel	3
Polymeric nanocomposite hydrogel scaffold for jawbone regeneration: The role of rosuvastatin calcium-loaded silica nanoparticles	3
Autoencoder-based inverse design and surrogate-based optimization of an integrated wet granulation manufacturing process	3
The effect of exhalation before the inhalation of dry powder aerosol drugs on the breathing parameters, emitted doses and aerosol size distributions	3
3D printed infliximab suppositories for rectal biologic delivery	3
Polymorphic transitions in flufenamic acid-trehalose composites	3
Functionalized surface of PLGA nanoparticles in thermosensitive gel to enhance the efficacy of antibiotics against antibiotic resistant infections in endodontics: A randomized clinical trial	3
RP-HPLC-CAD method for the rapid analysis of lipids used in lipid nanoparticles derived from dual centrifugation	3
Oxidation of polysorbates – An underestimated degradation pathway?	3
Small-volume in vitro lipid digestion measurements for assessing drug dissolution in lipid-based formulations using SAXS	3
Non-invasive caffeinated-nanovesicles as adipocytes-targeted therapy for cellulite and localized fats	3
Biological activity of gold nanoparticles combined with the NFL-TBS.40-63 peptide, or with other cell penetrating peptides, on rat glioblastoma cells	3
End-point determination of heterogeneous formulations using inline torque measurements for a high-shear wet granulation process	3
Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration	3

In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole	3
3D printing of amorphous solid dispersions: A comparison of fused deposition modeling and drop-on-powder printing	3
Continuous direct compression: Development of an empirical predictive model and challenges regarding PAT implementation	3
Polycarboxybetaine in advanced drug delivery systems: From structure-function relationship to therapeutic applications	2
Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness, variability, film homogeneity and roughness	2
Pectin nanoparticles loaded with nitric oxide donor drug: A potential approach for tissue regeneration	2
Polycaprolactone – Vitamin E TPGS micelles for delivery of paclitaxel: In vitro and in vivo evaluation	2
Processability of mesoporous materials in fused deposition modeling for drug delivery of a model thermolabile drug	2
Off-the-shelf medication transformed: Custom-dosed metoprolol tartrate tablets via semisolid extrusion additive manufacturing and the perception of this technique in a hospital context	2
The characteristics and biological activity enhancements of melatonin encapsulations for skin care product applications	2
How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up	2
Terahertz time-domain spectroscopy for powder compact porosity and pore shape measurements: An error analysis of the anisotropic bruggeman model	2
An examination of process models and model risk frameworks for pharmaceutical manufacturing	2
Starch nanoparticles improve curcumin-induced production of anti-inflammatory cytokines in intestinal epithelial cells	2
Development and optimization of vildagliptin solid lipid nanoparticles loaded ocuserts for controlled ocular delivery: A promising approach towards treating diabetic retinopathy	2
Sustained release of therapeutic gene by injectable hydrogel for hepatocellular carcinoma	2
Corrigendum to “Impact of polymer chemistry on critical quality attributes of selective laser sintering 3D printed solid oral dosage forms” [International Journal of Pharmaceutics:X Volume 6 (2023) 10	2
Ethoxy acetalated dextran nanoparticles for drug delivery: A comparative study of formulation methods	2
Ocular mucoadhesive and biodegradable spanlastics loaded cationic spongy insert for enhancing and sustaining the anti-inflammatory effect of prednisolone Na phosphate; Preparation, I-optimal optimizat	2
Poly(pseudo)rotaxanes formed by mixed micelles and α-cyclodextrin enhance terbinafine nail permeation to deeper layers	2
Impact of process stress on protein stability in highly-loaded solid protein/PEG formulations from small-scale melt extrusion	2
Investigating the role of excipients on the physical stability of directly compressed tablets	2
Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology	2
Trends in amorphous solid dispersion drug products approved by the U.S. Food and Drug Administration between 2012 and 2023	2
At-line porosity sensing for non-destructive disintegration testing in immediate release tablets	2
Novel nasal niosomes loaded with lacosamide and coated with chitosan: A possible pathway to target the brain to control partial-onset seizures	2
Research on the loading and release kinetics of the vincristine sulfate liposomes and its anti-breast cancer activity	2
Integrating pressure sensor control into semi-solid extrusion 3D printing to optimize medicine manufacturing	2
Mechanistic insights of desmopressin loaded elastic liposomes for transdermal delivery: HSPiP predictive parameters and instrumental based evidences	2
Batch versus continuous blending of binary and ternary pharmaceutical powder mixtures	2
Advanced applications of smart electrospun nanofibers in cancer therapy: With insight into material capabilities and electrospinning parameters	1
Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions	1
Process intensification of pharmaceutical powder blending at commercial throughputs by utilizing semi-continuous mini-blending	1
Spanlastic-laden nanogel as a plausible platform for dermal delivery of bimatoprost with superior cutaneous deposition and hair regrowth efficiency in androgenic alopecia	1
Development and optimization of the Glabridin-loaded dissolving microneedle for enhanced treatment of keloid	1
Editorial Board	1
Development of 3D-printed vaginal devices containing metronidazole for alternative bacterial vaginosis treatment	1
The impact of solvent selection on the characteristics of niosome nanoparticles prepared by microfluidic mixing	1
Digitalization in pharmaceutical industry: What to focus on under the digital implementation process?	1
Efficacy optimization of low frequency microbubble-mediated sonoporation as a drug delivery platform to cancer cells	1
A model-based optimization strategy to achieve fast and robust freeze-drying cycles	1
Nanomedicine-based disulfiram and metal ion co-delivery strategies for cancer treatment	1
Effect of wound dressing porosity and exudate viscosity on the exudate absorption: In vitro and in silico tests with 3D printed hydrogels	1
Resveratrol liposomes reverse sorafenib resistance in renal cell carcinoma models by modulating PI3K-AKT-mTOR and VHL-HIF signaling pathways	1
Influence of probiotic bacteria on gut microbiota composition and gut wall function in an in-vitro model in patients with Parkinson's disease	1
Reactive oxygen species responsive double-locked liposome collaborative photodynamic therapy for reducing electrical conduction recurrence after radiofrequency catheter ablation	1
Corrigendum to “Quantitative comparison of the protein corona of nanoparticles with different matrices” [Int J Pharm X 2022 Oct 21;4: 100136]	1
Development of a novel intramuscular liposomal injection for advanced meloxicam delivery: Preparation, characterization, in vivo pharmacokinetics, pharmacodynamics, and pain assessment in an orthopedi	1
Highly protein-loaded melt extrudates produced by small-scale ram and twin-screw extrusion - evaluation of extrusion process design on protein stability by experimental and numerical approaches	1
Dual-responsive chondroitin sulfate self-assembling nanoparticles for combination therapy in metastatic cancer cells	1
On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients	1
The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation proce	1
Trastuzumab-functionalized SK-BR-3 cell membrane-wrapped mesoporous silica nanoparticles loaded with pyrotinib for the targeted therapy of HER-2-positive breast cancer	1
Comprehensive analysis of lipid nanoparticle formulation and preparation for RNA delivery	1
QbD-guided phospholipid-tagged nanonized boswellic acid naturosomal delivery for effective rheumatoid arthritis treatment	1
From lab to industrial development of lipid nanocarriers using quality by design approach	1
The effect of mAb and excipient cryoconcentration on long-term frozen storage stability – Part 1: Higher molecular weight species and subvisible particle formation	1
Augmented glycerosomes as a promising approach against fungal ear infection: Optimization and microbiological, ex vivo and in vivo assessments	1
Nanoscale metal-organic frameworks for the delivery of nucleic acids to cancer cells	1
EVA implants for controlled drug delivery to the inner ear	1
Chicken embryo model for in vivo acute toxicological and antitumor efficacy evaluation of lipid nanocarrier containing doxorubicin	1
Protein photodegradation in the visible range? Insights into protein photooxidation with respect to protein concentration	1
Halofuginone-guided nano-local therapy: Nano-thermosensitive hydrogels for postoperative metastatic canine mammary carcinoma with scar removal	1
Evaluation of gender differences in the pharmacokinetics of oral zileuton nanocrystalline formulation using a rat model	1
Predicting pharmaceutical inkjet printing outcomes using machine learning	1
Heparin interferes with the uptake of liposomes in glioma	1
β-Cyclodextrin metal-organic framework as a green carrier to improve the dissolution, bioavailability, and liver protective effect of luteolin	1
Exploring the landscape of Lipid Nanoparticles (LNPs): A comprehensive review of LNPs types and biological sources of lipids	1