OOIR: Observatory of International Research

Papers

(The TQCC of International Journal of Pharmaceutics-X is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Oral etoposide and zosuquidar bioavailability in rats: Effect of co-administration and in vitro-in vivo correlation of P-glycoprotein inhibition	89
Tailored ASD destabilization - Balancing shelf life stability and dissolution performance with hydroxypropyl cellulose	40
Phloretin-nanospanlastics for targeting the Akt/PI3K signaling pathways in dimethylhydrazine-induced colon cancer in mice	25
Rationalized landscape on protein-based cancer nanomedicine: Recent progress and challenges	25
Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations	23
Exploiting recent trends for the synthesis and surface functionalization of mesoporous silica nanoparticles towards biomedical applications	21
Exploring high-throughput synchrotron X-Ray powder diffraction for the structural analysis of pharmaceuticals	20
Autoencoder-based inverse design and surrogate-based optimization of an integrated wet granulation manufacturing process	20
Polydopamine-activated celastrol carbon dots for synergistic chemotherapy-photothermal therapy of tumors	16
Enhancing oocyte in vitro maturation and quality by melatonin/bilirubin cationic nanoparticles: A promising strategy for assisted reproduction techniques	16
Everolimus-encapsulation in Pluronic P123 self-assembled micelles as drug delivery systems for drug-coated balloons	14
Erratum regarding missing Conflict of Interest statements in previously published articles	14
Formulating a heat- and shear-labile drug in an amorphous solid dispersion: Balancing drug degradation and crystallinity	13
Continuous direct compression: Development of an empirical predictive model and challenges regarding PAT implementation	13
Development, characterization, and in vitro evaluation of poly(ethylene oxide)-block-poly(ε-caprolactone)-α-tocopheryl succinate micelles as a novel nanocarrier for rapamycin delivery	12
RETRACTED: Corrigendum to “Impact of polymer chemistry on critical quality attributes of selective laser sintering 3D printed solid oral dosage forms” [International Journal of Pharmaceutics:X Volume	12
Impact of process stress on protein stability in highly-loaded solid protein/PEG formulations from small-scale melt extrusion	12
Polycaprolactone – Vitamin E TPGS micelles for delivery of paclitaxel: In vitro and in vivo evaluation	12
At-line porosity sensing for non-destructive disintegration testing in immediate release tablets	12
Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology	11
Corrigendum to “Quantitative comparison of the protein corona of nanoparticles with different matrices” [Int J Pharm X 2022 Oct 21;4: 100136]	11
Editorial Board	11
Spanlastic-laden nanogel as a plausible platform for dermal delivery of bimatoprost with superior cutaneous deposition and hair regrowth efficiency in androgenic alopecia	10
Preparation of chitosan-coated hollow tin dioxide nanoparticles and their application in improving the oral bioavailability of febuxostat	10
A tabletability change classification system in supporting the tablet formulation design via the roll compaction and dry granulation process	10

Predicting pharmaceutical inkjet printing outcomes using machine learning	10
A network of regulatory innovations to improve FDA quality assessments of human drug applications	10
A new engineering process of biodegradable polymeric solid implants for ultra-long-acting drug delivery	9
A model-based optimization strategy to achieve fast and robust freeze-drying cycles	9
Preservative-free electrospun nanofibrous inserts for sustained delivery of ceftazidime; design, characterization and pharmacokinetic investigation in rabbit's eye	9
Formulation of multicomponent inclusion complex of cyclodextrin-amino acid with Chrysin: Physicochemical characterization, cell viability and apoptosis assessment in human primary glioblastoma cell li	9
Formulation, in silico, in vitro characterization, cytotoxicity and cellular uptake of cyclodextrin complexes and ion pairing/salt formation with functional excipients (azelaic acid, tartaric acid, an	9
Box Behnken optimization of cubosomes for enhancing the anticancer activity of metformin: Design, characterization, and in-vitro cell proliferation assay on MDA-MB-231 breast and LOVO colon cancer cel	9
Stability of Dexamethasone during Hot-Melt Extrusion of Filaments based on Eudragit® RS, Ethyl Cellulose and Polyethylene Oxide	9
Fucoidan/Polyvinylpyrrolidone/Hesperitin nanoparticle complex for corneal injury treatment: Synthesis, characterization, and therapeutic efficacy	8
HSPiP and QbD oriented optimized stearylamine-elastic liposomes for topical delivery of ketoconazole to treat deep seated fungal infections: In vitro and ex vivo evaluations	8
Repurposing celecoxib for colorectal cancer targeting via pH-triggered ultra-elastic nanovesicles: Pronounced efficacy through up-regulation of Wnt/β-catenin pathway in DMH-induced tumorigenesis	8
Formulation, optimization and evaluation of ocular gel containing nebivolol Hcl-loaded ultradeformable spanlastics nanovesicles: In vitro and in vivo studies	8
The shelf life of ASDs: 2. Predicting the shelf life at storage conditions	8
Synergistic effect of doxorubicin lauroyl hydrazone derivative delivered by α-tocopherol succinate micelles for the treatment of glioblastoma	8
Multifunctional poloxamer-based thermo-responsive hydrogel loaded with human lactoferricin niosomes: In vitro study on anti-bacterial activity, accelerate wound healing, and anti-inflammation	8
Formulation, optimization, in-vivo biodistribution studies and histopathological safety assessment of duloxetine HCl-loaded ultra-elastic nanovesicles for antidepressant effect after intranasal and tr	8
Nanoparticles design considerations to co-deliver nucleic acids and anti-cancer drugs for chemoresistance reversal	8
The effect of black tea and water temperature on the disintegration of gelatine and HPMC capsules, tested with the paddle device, GastroDuo and in vivo pharmacokinetics: Much ado about little	7
Curcumin and EGCG combined formulation in nanostructured lipid carriers for anti-aging applications	7
RETRACTED: Development of thermosensitive hydrogel of Amphotericin-B and Lactoferrin combination-loaded PLGA-PEG-PEI nanoparticles for potential eradication of ocular fungal infections: In-vitro, ex-v	7
Editorial board	7
Multifunctional Bi2S3-Au nanoclusters for fluorescence/infrared thermal imaging guided photothermal therapy	7
How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up	7
Towards a better understanding of thermally treated polycarbophil matrix tablets for controlled release	7
Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings	7
Ocular mucoadhesive and biodegradable spanlastics loaded cationic spongy insert for enhancing and sustaining the anti-inflammatory effect of prednisolone Na phosphate; Preparation, I-optimal optimizat	7
RP-HPLC-CAD method for the rapid analysis of lipids used in lipid nanoparticles derived from dual centrifugation	6
The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation proce	6
The impact of solvent selection on the characteristics of niosome nanoparticles prepared by microfluidic mixing	6
Nanoscale metal-organic frameworks for the delivery of nucleic acids to cancer cells	6
Retraction notice to “Corrigendum to “Impact of polymer chemistry on critical quality attributes of selective laser sintering 3D printed solid oral dosage forms” [International Journal of Pharmaceutic	6
Oxidation of polysorbates – An underestimated degradation pathway?	6
Atorvastatin-loaded emulsomes foam as a topical antifungal formulation	6
Neutrophils-mediated accelerated blood clearance phenomenon in beagles and rats based on the cross-injection of non-PEGylated and PEGylated nanoemulsions	6
Development and optimization of vildagliptin solid lipid nanoparticles loaded ocuserts for controlled ocular delivery: A promising approach towards treating diabetic retinopathy	6
Reactive oxygen species responsive double-locked liposome collaborative photodynamic therapy for reducing electrical conduction recurrence after radiofrequency catheter ablation	6
Co-assembled Glycyrrhiza nanoparticles embedded supramolecular protein hydrogels to enhance licochalcone A release for acute inflammation management	6
Process intensification of pharmaceutical powder blending at commercial throughputs by utilizing semi-continuous mini-blending	6
Developments in image-based colorimetric analysis methods and applications of CIElab color space in pharmaceutical sciences: A narrative review	5
In vitro synergistic activity of cisplatin and EGFR-targeted nanomedicine of anti-Bcl-xL siRNA in a non-small lung cancer cell line model	5
Functional candesartan loaded lipid nanoparticles for the control of diabetes-associated stroke: In vitro and in vivo studies	5
Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy	5
β-Cyclodextrin metal-organic framework as a green carrier to improve the dissolution, bioavailability, and liver protective effect of luteolin	5
Investigation on the self-assembly of the NFL-TBS.40-63 peptide and its interaction with gold nanoparticles as a delivery agent for glioblastoma	5
Characterization and quantification of the interaction between the NFL-TBS.40‐63 peptide and lipid nanocapsules	5
Modelling intramuscular drug fate in vitro with tissue-relevant biomimetic hydrogels	5
M1 macrophage-membrane-cloaked paclitaxel/β-elemene nanoparticles targeting cervical cancer for enhanced therapy	5
Spanlastic-laden in situ gel as a promising approach for ocular delivery of Levofloxacin: In-vitro characterization, microbiological assessment, corneal permeability and in-vivo study	5
Transfer of a rational formulation and process development approach for 2D inks for pharmaceutical 2D and 3D printing	5

Editorial board	5
WITHDRAWN: The effect of particle size on the sublimation behavior of butylhydroxytoluene as antioxidant in tablets during storage and coating	5
The use of heat to deliver fentanyl via pulmonary drug delivery	5