OOIR: Observatory of International Research

Papers

(The median citation count of BMC Molecular and Cell Biology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Development of an in vitro human alveolar epithelial air-liquid interface model using a small molecule inhibitor cocktail	47
lncRNA ACTA2-AS1 predicts malignancy and poor prognosis of triple-negative breast cancer and regulates tumor progression via modulating miR-532-5p	30
Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact	27
Method for determining of cytotoxicity based on the release of fluorescent proteins	22
Intracellular targeting of Cisd2/Miner1 to the endoplasmic reticulum	19
Overexpressed cold inducible RNA-binding protein improves cell viability and EGF expression in glial cells	18
D-galactose-induced mitochondrial oxidative damage and apoptosis in the cochlear stria vascularis of mice	16
Upregulated dual oxidase 1-induced oxidative stress and caspase-1-dependent pyroptosis reflect the etiologies of heart failure	15
An alternative D. melanogaster 7SK snRNP	15
The role of the TGF-β/LIF signaling pathway mediated by SMADs during the cyst formation of Echinococcus in young children	12
SCAT8/miR-125b-5p axis triggers malignant progression of nasopharyngeal carcinoma through SCARB1	12
High levels of follicular fluid testosterone could impair oocyte developmental competency via affecting aryl hydrocarbon receptor pathway in PCOS patients	12
High miRNA-378 expression has high diagnostic values for pulmonary tuberculosis and predicts adverse outcomes	12
CTC together with Shh and Nrf2 are prospective diagnostic markers for HNSCC	11
Chromatin structure in cancer	11
Disruption of Drosophila larval muscle structure and function by UNC45 knockdown	11
Genotype-determined EGFR-RTK heterodimerization and its effects on drug resistance in lung Cancer treatment revealed by molecular dynamics simulations	11
The Glypican proteoglycans show intrinsic interactions with Wnt-3a in human prostate cancer cells that are not always associated with cascade activation	11
Evolutionary relevance of single nucleotide variants within the forebrain exclusive human accelerated enhancer regions	11
From network analysis to experimental validation: identification of regulators of non-muscle myosin II contractility using the folded-gastrulation signaling pathway	10
Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma	10
Simple, low-cost, and well-performing method, the outgrowth technique, for the isolation of cells from nasal polyps	10
LEP O-GlcNAcylation inactivates NF-κB pathway by suppressing LEP protein level and thus mediates cellular senescence and osteogenic differentiation in mouse mesenchymal stem cells	10
Glycyrrhizin inhibits LPS-induced inflammatory responses in goat ruminal epithelial cells in vitro	10
Long non-coding RNA SOX2OT in tamoxifen-resistant breast cancer	10

Mutant Fam20c knock-in mice recapitulate both lethal and non-lethal human Raine Syndrome	9
Optimization of fuzzy c-means (FCM) clustering in cytology image segmentation using the gray wolf algorithm	9
Impact of uORFs in mediating regulation of translation in stress conditions	9
The role of proteoglycan form of DMP1 in cranial repair	9
CREB1 regulates KPNA2 by inhibiting mir-495-3p transcription to control melanoma progression	9
Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs	9
Hik28-dependent and Hik28-independent ABC transporters were revealed by proteome-wide analysis of ΔHik28 under combined stress	8
Systematic study of single-cell isolation from musculoskeletal tissues for single-sell sequencing	8
Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells	8
N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin α5/β1/PI3K/AKT signaling	8
Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor	7
Hyperoxia exposure upregulates Dvl-1 and activates Wnt/β-catenin signaling pathway in newborn rat lung	7
Lncap-AI prostate cancer cell line establishment by Flutamide and androgen-free environment to promote cell adherent	7
Evaluation of antibacterial and anticancer properties of secondary metabolites isolated from soil Bacillus spp focusing on two strains of Bacillus licheniformis and Bacillus siamensis	7
Association between plasma L-carnitine levels and mitochondrial DNA copy number	7
Urine-derived mesenchymal stem cells-derived exosomes enhances survival and proliferation of aging retinal ganglion cells	7
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells	7
Janus Kinase 3 phosphorylation and the JAK/STAT pathway are positively modulated by follicle-stimulating hormone (FSH) in bovine granulosa cells	6
Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer	6
Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance	6
Extracellular matrix alterations in the skin of patients affected by psoriasis	6
Single-cell RNA sequencing identifies the expression of hemoglobin in chondrocyte cell subpopulations in osteoarthritis	6
IDPsBind: a repository of binding sites for intrinsically disordered proteins complexes with known 3D structures	6
NanoBRET in C. elegans illuminates functional receptor interactions in real time	6
Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function	6
BRAF regulates circPSD3/miR-526b/RAP2A axis to hinder papillary thyroid carcinoma progression	5
Comparative transcriptomic analysis reveals gene regulation mediated by caspase activity in a chordate organism	5
Differential methylation patterns in paternally imprinted gene promoter regions in sperm from hepatitis B virus infected individuals	5
Transient activation of YAP/TAZ confers resistance to morusin-induced apoptosis	5
Association of Sonic Hedgehog with the extracellular matrix requires its zinc-coordination center	5
Exportin Crm1 is important for Swi6 nuclear shuttling and MBF transcription activation in Saccharomyces cerevisiae	5
Acetaminophen changes the RNA m6A levels and m6A-related proteins expression in IL-1β-treated chondrocyte cells	5
Downregulation of miR-451 in cholangiocarcinoma help the diagnsosi and promotes tumor progression	5
High D-glucose levels induce ACE2 expression via GLUT1 in human airway epithelial cell line Calu-3	4
CLCA2 overexpression suppresses epithelial-to-mesenchymal transition in cervical cancer cells through inactivation of ERK/JNK/p38-MAPK signaling pathways	4
A computational peptide model induces cancer cells’ apoptosis by docking Kringle 5 to GRP78	4
CARD9 contributes to ovarian cancer cell proliferation, cycle arrest, and cisplatin sensitivity	4
Mesenchymal stem cells- derived exosomes inhibit the expression of Aquaporin-5 and EGFR in HCT-116 human colorectal carcinoma cell line	4
SH3BGRL3 binds to myosin 1c in a calcium dependent manner and modulates migration in the MDA-MB-231 cell line	4
Mechanical stretch leads to increased caveolin-1 content and mineralization potential in extracellular vesicles from vascular smooth muscle cells	4
Exogenous 8-hydroxydeoxyguanosine attenuates doxorubicin-induced cardiotoxicity by decreasing pyroptosis in H9c2 cardiomyocytes	4
The proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs)	4
Systemic administration of c-Kit+ cells diminished pulmonary and vascular inflammation in rat model of chronic asthma	4
The dual role of Nrf2 in melanoma: a systematic review	4
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway	4
Induction of iPSC-derived Prg4-positive cells with characteristics of superficial zone chondrocytes and fibroblast-like synovial cells	4
ARNTL2 upregulation of ACOT7 promotes NSCLC cell proliferation through inhibition of apoptosis and ferroptosis	4
Effect of Voacamine upon inhibition of hypoxia induced fatty acid synthesis in a rat model of methyln-nitrosourea induced mammary gland carcinoma	3
Correction: The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts	3
MDMX is essential for the regulation of p53 protein levels in the absence of a functional MDM2 C-terminal tail	3

KDM6A mutations promote acute cytoplasmic DNA release, DNA damage response and mitosis defects	3
Optimisation of cryopreservation conditions, including storage duration and revival methods, for the viability of human primary cells	3
Pre-treatment with IL-6 potentiates β-cell death induced by pro-inflammatory cytokines	3
Correction to: A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation	3
Nucleolar localization of the ErbB3 receptor as a new target in glioblastoma	3
Cyr61 promotes Schwann cell proliferation and migration via αvβ3 integrin	3
A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation	3
Correction: Glycogen Synthase Kinase-3 regulates IGFBP-1 gene transcription through the Thymine-rich Insulin Response Element	3
Spinoculation and retronectin highly enhance the gene transduction efficiency of Mucin-1-specific chimeric antigen receptor (CAR) in human primary T cells	3
Comprehensive brain tissue metabolomics and biological network technology to decipher the mechanism of hydrogen-rich water on Radiation-induced cognitive impairment in rats	3
SEM and TEM for identification of capsular fibrosis and cellular behavior around breast implants – a descriptive analysis	3
Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway	2
The DNA demethylation-regulated SFRP2 dictates the progression of endometriosis via activation of the Wnt/β-catenin signaling pathway	2
MAPKAPK5-AS1 drives the progression of hepatocellular carcinoma via regulating miR-429/ZEB1 axis	2
Construction and characterization of EGFP reporter plasmid harboring putative human RAX promoter for in vitro monitoring of retinal progenitor cells identity	2
Activated TRPA1 plays a therapeutic role in TMZ resistance in glioblastoma by altering mitochondrial dynamics	2
Comparing chemical transfection, electroporation, and lentiviral vector transduction to achieve optimal transfection conditions in the Vero cell line	2
Transcriptome and DNA methylation profiling during the NSN to SN transition in mouse oocytes	2
The absence of the autoimmune regulator gene (AIRE) impairs the three-dimensional structure of medullary thymic epithelial cell spheroids	2
TonEBP/NFAT5 expression is associated with cisplatin resistance and migration in macrophage-induced A549 cells	2
Normal seminal plasma could preserve human spermatozoa against cryopreservation damages in Oligozoospermic patients	2
sFLT01 modulates invasion and metastasis in prostate cancer DU145 cells by inhibition of VEGF/GRP78/MMP2&9 axis	2
High-fat diet enhances cell proliferation and compromises intestinal permeability in a translational canine intestinal organoid model	2
The 3D nuclear conformation of the major histocompatibility complex changes upon cell activation both in porcine and human macrophages	2
Uncarboxylated osteocalcin alleviates the inhibitory effect of high glucose on osteogenic differentiation of mouse bone marrow–derived mesenchymal stem cells by regulating TP63	2
Functional significance of some common oxytocin receptor SNPs involved in complex human traits	2
Effect of Emi1 gene silencing on the proliferation and invasion of human breast cancer cells	2
Melatonin reduces lung injury in type 1 diabetic mice by the modulation of autophagy	2
Protein kinase C regulates organic anion transporter 1 through phosphorylating ubiquitin ligase Nedd4–2	2
In silico prediction, characterization, docking studies and molecular dynamics simulation of human p97 in complex with p37 cofactor	2
Lack of Nck1 protein and Nck-CD3 interaction caused the increment of lipid content in Jurkat T cells	2
Prioritization of Trypanosoma brucei editosome protein interactions interfaces at residue resolution through proteome-scale network analysis	2
A computational model of mutual antagonism in the mechano-signaling network of RhoA and nitric oxide	2
Convergent evolution of type I antifreeze proteins from four different progenitors in response to global cooling	2
Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress	2