OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cancer is 75. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Untangling the threads of immunotherapy research	589
Outcompeting neighbors for intestinal cancer initiation	388
Gut decisions in CAR T cell therapy	381
Alzheimer’s drug turns macrophages against cancer	349
PARP11 interfer(on)es with CAR T cell efficacy	346
Enhancing childhood cancer targetability	314
Shooting for multiplexed pathology with Orion	295
Author Correction: Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling	293
Author Correction: Breaking the performance ceiling for neoantigen immunogenicity prediction	289
A macrophage-activated abscopal effect	257
Breaking frontiers with multidisciplinary cancer research	232
MALAT1 protects dormant tumor cells from immune elimination	222
An oncolytic circular RNA therapy	199
Single-cell transcriptomic landscape deciphers olfactory neuroblastoma subtypes and intra-tumoral heterogeneity	199
A single-cell map of dynamic chromatin landscapes of immune cells in renal cell carcinoma	193
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC	187
A low-coverage liquid biopsy for lung cancer	183
Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms	181
Author Correction: IL-17A-secreting γδ T cells promote resistance to CDK4/CDK6 inhibitors in HR+HER2− breast cancer via CX3CR1+ macrophages	177
Breast cancer cells survive chemotherapy by activating targetable immune-modulatory programs characterized by PD-L1 or CD80	174
ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung	159
Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer	148
The cGAS–STING pathway and cancer	144
Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial	139
Considering molecular alterations as pan-cancer tissue-agnostic targets	129

Expanding the options for KRAS inhibition	126
The importance of being generous	125
Reflecting on the golden age of cancer research	119
DePICting T cell–APC crosstalk in cancer	116
Beating cancer one carbon at a time	115
Adoptively transferred tumor-specific IL-9-producing cytotoxic CD8+ T cells activate host CD4+ T cells to control tumors with antigen loss	113
Stress granules shape metabolic reprogramming and drug resistance	113
Bone marrow progenitor-like cells against leukemia cure	112
Palmitate oxidation drives a pro-metastatic post-translational modification	111
Advancing therapeutics in small-cell lung cancer	108
Determinants of resistance and response to melanoma therapy	106
Shaping the microenvironment in peritoneal metastases	106
Impact of context-dependent autophagy states on tumor progression	106
A targetable type III immune response with increase of IL-17A expressing CD4+ T cells is associated with immunotherapy-induced toxicity in melanoma	106
Reply to: Ricolinostat is not a highly selective HDAC6 inhibitor	100
crossNN is an explainable framework for cross-platform DNA methylation-based classification of tumors	97
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia	97
Targeting PRMT9-mediated arginine methylation suppresses cancer stem cell maintenance and elicits cGAS-mediated anticancer immunity	94
A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy	94
Engineering-enhanced CAR T cells for improved cancer therapy	93
The labors of referees	92
LAG-3 and PD-1 blockade raises the bar for melanoma	91
Integrative single-cell analysis of human colorectal cancer reveals patient stratification with distinct immune evasion mechanisms	90
Thriving in diverse ecosystems	90
Cycling back to folate metabolism in cancer	90
A quick guide for clinical oncology	86
Inflammation meets translation in AML	84
Antibody avidity meets multiple myeloma	83
Sarcoma ecotypes determine immunotherapy benefit	83
A comeback for checkpoint inhibition in multiple myeloma	83
Sex-specific gut microbiota and neutrophil senescence in bladder cancer	81
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer	81
Author Correction: Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma	81
Clinical implementation of artificial-intelligence-assisted detection of breast cancer metastases in sentinel lymph nodes: the CONFIDENT-B single-center, non-randomized clinical trial	80
Circadian regulation of cancer stem cells and the tumor microenvironment during metastasis	80
Innate immunity drives epithelial cell plasticity during prostate tumor formation	80
A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia	80
Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers	79
Loss of the receptors ER, PR and HER2 promotes USP15-dependent stabilization of PARP1 in triple-negative breast cancer	79
Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling	78
Proteogenomic landscape of human pancreatic ductal adenocarcinoma in an Asian population reveals tumor cell-enriched and immune-rich subtypes	78
INPP5A phosphatase is a synthetic lethal target in GNAQ and GNA11-mutant melanomas	77
Radioligand cancer therapy comes to the fore	76
Immunosuppressive dura-derived macrophages in leptomeningeal metastasis	76
Regulatory T cells play a crucial part in radio-immunotherapy resistance of brain tumors	76
Radiation sparks a dark side in neutrophils	75
MCL1 inhibitor BRD-810 kills cancer cells while minimizing risk of cardiotoxicity	75
How AI agents will change cancer research and oncology	75
Building a translational cancer dependency map for The Cancer Genome Atlas	75
Bispecific antibodies seek out colon cancer stem cells	75